CN1568184A - 烟碱乙酰胆碱受体激动剂在治疗多动腿综合征中的用途 - Google Patents
烟碱乙酰胆碱受体激动剂在治疗多动腿综合征中的用途 Download PDFInfo
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- CN1568184A CN1568184A CNA028200292A CN02820029A CN1568184A CN 1568184 A CN1568184 A CN 1568184A CN A028200292 A CNA028200292 A CN A028200292A CN 02820029 A CN02820029 A CN 02820029A CN 1568184 A CN1568184 A CN 1568184A
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- Prior art keywords
- ring
- alkyl
- azepine
- triolefin
- tridecane
- Prior art date
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- 239000008107 starch Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 238000010254 subcutaneous injection Methods 0.000 description 1
- 239000007929 subcutaneous injection Substances 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 238000009923 sugaring Methods 0.000 description 1
- 239000006228 supernatant Substances 0.000 description 1
- 239000000829 suppository Substances 0.000 description 1
- 239000000375 suspending agent Substances 0.000 description 1
- 239000006188 syrup Substances 0.000 description 1
- 235000020357 syrup Nutrition 0.000 description 1
- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- VRGVVJHPLVPFRR-UHFFFAOYSA-N thiomorpholine Chemical group C1CSCCN1.C1CSCCN1 VRGVVJHPLVPFRR-UHFFFAOYSA-N 0.000 description 1
- JOXIMZWYDAKGHI-UHFFFAOYSA-N toluene-4-sulfonic acid Chemical compound CC1=CC=C(S(O)(=O)=O)C=C1 JOXIMZWYDAKGHI-UHFFFAOYSA-N 0.000 description 1
- 229960004380 tramadol Drugs 0.000 description 1
- TVYLLZQTGLZFBW-GOEBONIOSA-N tramadol Natural products COC1=CC=CC([C@@]2(O)[C@@H](CCCC2)CN(C)C)=C1 TVYLLZQTGLZFBW-GOEBONIOSA-N 0.000 description 1
- 229940125725 tranquilizer Drugs 0.000 description 1
- 239000003204 tranquilizing agent Substances 0.000 description 1
- 230000002936 tranquilizing effect Effects 0.000 description 1
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 1
- LLPOLZWFYMWNKH-UHFFFAOYSA-N trans-dihydrocodeinone Natural products C1C(N(CCC234)C)C2CCC(=O)C3OC2=C4C1=CC=C2OC LLPOLZWFYMWNKH-UHFFFAOYSA-N 0.000 description 1
- OVCXRBARSPBVMC-UHFFFAOYSA-N triazolopyridine Chemical compound C=1N2C(C(C)C)=NN=C2C=CC=1C=1OC=NC=1C1=CC=C(F)C=C1 OVCXRBARSPBVMC-UHFFFAOYSA-N 0.000 description 1
- ITMCEJHCFYSIIV-UHFFFAOYSA-M triflate Chemical compound [O-]S(=O)(=O)C(F)(F)F ITMCEJHCFYSIIV-UHFFFAOYSA-M 0.000 description 1
- 229940054370 ultram Drugs 0.000 description 1
- 229940000146 vicodin Drugs 0.000 description 1
- 230000021542 voluntary musculoskeletal movement Effects 0.000 description 1
- 239000003643 water by type Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33481001P | 2001-10-31 | 2001-10-31 | |
| US60/334,810 | 2001-10-31 | ||
| US33585801P | 2001-11-26 | 2001-11-26 | |
| US60/335,858 | 2001-11-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1568184A true CN1568184A (zh) | 2005-01-19 |
Family
ID=26989404
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA028200292A Pending CN1568184A (zh) | 2001-10-31 | 2002-10-21 | 烟碱乙酰胆碱受体激动剂在治疗多动腿综合征中的用途 |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP1439836A1 (fr) |
| JP (1) | JP2005507411A (fr) |
| KR (1) | KR20050038583A (fr) |
| CN (1) | CN1568184A (fr) |
| BR (1) | BR0213696A (fr) |
| CA (1) | CA2460118A1 (fr) |
| CZ (1) | CZ2004524A3 (fr) |
| HU (1) | HUP0401967A2 (fr) |
| IL (1) | IL160967A0 (fr) |
| MX (1) | MXPA04002539A (fr) |
| PL (1) | PL370549A1 (fr) |
| SK (1) | SK1912004A3 (fr) |
| TW (1) | TW200300139A (fr) |
| WO (1) | WO2003037329A1 (fr) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1633358A1 (fr) * | 2003-05-20 | 2006-03-15 | Pfizer Products Inc. | Compositions pharmaceutiques a base de varenicline |
| NZ545989A (en) | 2003-09-17 | 2009-10-30 | Xenoport Inc | Treating or preventing restless legs syndrome using prodrugs of gaba analogs |
| BRPI0617165B1 (pt) | 2005-10-07 | 2023-10-03 | Exelixis Inc | Compostos inibidores mek, composições farmacêuticas que os contem e métodos de uso dos mesmos |
| CN111643496A (zh) | 2006-12-14 | 2020-09-11 | 埃克塞利希斯股份有限公司 | 使用mek抑制剂的方法 |
| ES2700473T3 (es) * | 2012-07-27 | 2019-02-18 | Neurodyn Life Sciences Inc | Biodisponibilidad cerebral mejorada de galantamina mediante formulaciones seleccionadas y administración transmucosa de profármacos lipofílicos |
| ES2880399T3 (es) | 2012-07-27 | 2021-11-24 | Neurodyn Life Sciences Inc | Biodisponibilidad cerebral mejorada de galantamina mediante formulaciones seleccionadas y administración transmucosa de profármacos lipofílicos |
| CN104837826B (zh) | 2012-10-12 | 2018-07-27 | 埃克塞里艾克西斯公司 | 制备用于治疗癌症的化合物的新型方法 |
| US10568852B2 (en) * | 2015-05-22 | 2020-02-25 | Helmholtz Zentrum Munchen - Deutsches Forschungszentrum Fur Gesundheit Und Umwelt (Gmbh) | Combination compositions and their use in methods for treating obesity and obesity-related disorders |
| WO2018236957A1 (fr) * | 2017-06-20 | 2018-12-27 | Nexien Biopharma, Inc. | Procédé et compositions permettant de traiter le syndrome des jambes sans repos |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6020335A (en) * | 1997-02-06 | 2000-02-01 | Pfizer Inc | (N-(pyridinylmethyl)-heterocyclic)ylideneamine compounds as nicotinic acetylcholine receptor binding agents |
| US5977131A (en) * | 1997-04-09 | 1999-11-02 | Pfizer Inc. | Azaindole-ethylamine derivatives as nicotinic acetylcholine receptor binding agents |
| US6605610B1 (en) * | 1997-12-31 | 2003-08-12 | Pfizer Inc | Aryl fused azapolycyclic compounds |
| EP0955301A3 (fr) * | 1998-04-27 | 2001-04-18 | Pfizer Products Inc. | Dérivés de 7-aza-bicyclo[2.2.1]-heptane, leur préparation et utilisation sur la base d'affinité pour les recepteurs de l'acetylcholine nicotinique neuronaux |
| PT1076650E (pt) * | 1998-04-29 | 2004-05-31 | Pfizer Prod Inc | Compostos azapoliciclicos fundidos com arilo |
-
2002
- 2002-10-21 PL PL02370549A patent/PL370549A1/xx not_active Application Discontinuation
- 2002-10-21 EP EP02802239A patent/EP1439836A1/fr not_active Withdrawn
- 2002-10-21 MX MXPA04002539A patent/MXPA04002539A/es unknown
- 2002-10-21 CZ CZ2004524A patent/CZ2004524A3/cs unknown
- 2002-10-21 KR KR1020047006544A patent/KR20050038583A/ko not_active Application Discontinuation
- 2002-10-21 JP JP2003539673A patent/JP2005507411A/ja active Pending
- 2002-10-21 SK SK191-2004A patent/SK1912004A3/sk not_active Application Discontinuation
- 2002-10-21 BR BR0213696-1A patent/BR0213696A/pt not_active IP Right Cessation
- 2002-10-21 CA CA002460118A patent/CA2460118A1/fr not_active Abandoned
- 2002-10-21 CN CNA028200292A patent/CN1568184A/zh active Pending
- 2002-10-21 WO PCT/IB2002/004379 patent/WO2003037329A1/fr not_active Application Discontinuation
- 2002-10-21 IL IL16096702A patent/IL160967A0/xx unknown
- 2002-10-21 HU HU0401967A patent/HUP0401967A2/hu unknown
- 2002-10-30 TW TW091132199A patent/TW200300139A/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CZ2004524A3 (cs) | 2004-07-14 |
| PL370549A1 (en) | 2005-05-30 |
| KR20050038583A (ko) | 2005-04-27 |
| IL160967A0 (en) | 2004-08-31 |
| BR0213696A (pt) | 2004-10-26 |
| JP2005507411A (ja) | 2005-03-17 |
| CA2460118A1 (fr) | 2003-05-08 |
| MXPA04002539A (es) | 2004-05-31 |
| WO2003037329A1 (fr) | 2003-05-08 |
| HUP0401967A2 (hu) | 2005-01-28 |
| EP1439836A1 (fr) | 2004-07-28 |
| TW200300139A (en) | 2003-05-16 |
| SK1912004A3 (en) | 2004-09-08 |
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