CN1559502A - Chinese medicinal composition for treating sexual dysfunction - Google Patents

Chinese medicinal composition for treating sexual dysfunction Download PDF

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CN1559502A
CN1559502A CNA2004100127530A CN200410012753A CN1559502A CN 1559502 A CN1559502 A CN 1559502A CN A2004100127530 A CNA2004100127530 A CN A2004100127530A CN 200410012753 A CN200410012753 A CN 200410012753A CN 1559502 A CN1559502 A CN 1559502A
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chinese medicine
radix
scolopendra
medicine composition
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CN1275618C (en
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王秋如
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Abstract

A Chinese medicine for treating sexual disfunction is prepared from 8-14 Chinese-medicinal materials including centipede, Chinese angelica root, fleece flower root, cloves, etc through proportional dispensing.

Description

The handicapped Chinese medicine composition of a kind of therapeutic
Technical field
The present invention relates to the handicapped Chinese medicine composition of a kind of therapeutic, belong to the field of Chinese medicines.
Background technology
Sexual dysfunction such as functional impotence, premature ejaculation, necrospermia etc. are the common class diseases of adult male reproduction, mostly occur person between twenty and fifty at 30~50 years old, clinically mainly show as: sore waist and aching in the waist and the back, dizzy ear toot, fear of cold is afraid of cold, spiritlessness and weakness, shortness of breath and palpitation spontaneous perspiration, soft, the premature ejaculation of sexual life flaccidity, causes sexual dysfunctions such as few essence, necrospermia.Usually adopt: property treatment, physiotherapy, Drug therapy, surgical operation therapy etc., the traditional Chinese medical science belongs to kidney yang loss, deficiency of kidney yin etc. to the understanding of functional impotence more.At present Chinese medicine, Western medicine, Chinese medicine and western medicine mix preparation emerge in an endless stream, as " viagra " the Sexual health promotion medicine of etc.ing, divide take orally, two kinds of externals.A large amount of prior aries is also arranged at this problem in the traditional Chinese medicine technology, for example: application number: 00115791, denomination of invention: " a kind of medicine for the treatment of impotence ", it comprises following each component: Gecko, Rhizoma Corydalis, Herba Epimedii, Herba Cistanches, Fructus Tribuli, Fructus Cnidii, Fructus Corni, the Radix Astragali, Cortex Phellodendri.Two kinds of flavour of a drug components of Rhizoma Corydalis and Fructus Tribuli have been used in this medicine in a large number, both also use with transferring liver to invigorate blood circulation with kidney invigorating and YANG supporting, supporing yang road, be full of liver blood, regulation of mental activities chamber, make that kidney yang must be filled, essence and blood must be mended, qi tonifying and blood circulation promoting, have the advantage of " power is imitated fast by force ", can fundamentally treat diseases such as the slow sexual impotence of male effectively. And for example: application number: 01131796, denomination of invention: " handicapped Chinese medicine of therapeutic and preparation method thereof ", the present invention hides Chinese crude drugs by Folium Allii tuberosi seed, Gecko, Scolopendra, Concha Ostreae, Fructus Ligustri Lucidi etc. 17 and forms, and it is made powdery, mixes wine, steaming and decocting forms.The present invention starts with from conditioning human physiological functions, nourishing the brain and tranquilizing the mind, strengthening the tendons and bones, by stimulating endocrine, promotes Marjoram Extract, the YIN nourishing invigorating YANG, and the warming the meridian QI invigorating improves immunity.More than the effect that all can get sexual function improving, the physiological function of human body is recovered of two kinds of medicines.However, still do not have specific medicament for the therapeutic dysfunction, the curative effect of medicine of the prior art still can not be satisfactory.
Summary of the invention
Therefore, still there is the relatively little Chinese medicine preparation of the vast market demand, particularly toxicity, side effect in people for the medicaments for treating sexual disorder preparation of better efficacy.Up to the present, still find no the data of any destruction novelty of the present invention, present inventor people is through studying intensively for many years, by clinical practice and checking repeatedly, a large amount of clinical observation materials have been collected, obtain the Chinese medicine composition that the therapeutic dysfunction is had better curative effect, thereby finished the present invention.
Purpose of the present invention is exactly to provide a kind of therapeutic with better curative effect handicapped Chinese medicine composition.
The present invention is achieved in that it mainly is to be made by following bulk drugs: Scolopendra, Nidus Vespae, Radix Angelicae Sinensis, Radix Polygoni Multiflori, Flos Caryophylli, Cortex Cinnamomi, Fructus Piperis, Air Bladder pseudosciaenae seu Acipenser; In order to reach better therapeutic, crude drug of the present invention also can make up with the Radix Aucklandiae, Semen Ziziphi Spinosae; In order to reach better curative effect, also can on the basis of said medicine, add Herba Epimedii, Semen Allii Tuberosi, Semen Cuscutae, Gecko.
The various medicine property of medicine of the present invention: " Chinese medicine voluminous dictionary " ISBN7-5323-0842-1 of Shanghai science tech publishing house, ISBN7-5323-0843-X: Scolopendra (P2473): function cures mainly: dispel the wind arresting convulsion, merit poison, eliminating stagnation; Semen Ziziphi Spinosae (P2534) function cures mainly: nourishing the liver, and mind calming is calmed the nerves, arresting sweating; Radix Polygoni Multiflori (P1135): function cures mainly: tonifying liver, and kidney tonifying nourishes blood, and dispels the wind; The Radix Aucklandiae (P353): function cures mainly: promoting the circulation of QI to relieve pain, warming middle-JIAO for easing the stomach; Fructus Piperis (P1539): function cures mainly: warming middle-JIAO, the therapeutic method to keep the adverse QI flowing downwards, expectorant, detoxifcation; Herba Epimedii (P2250) function cures mainly: kidney invigorating and YANG supporting, expelling wind and removing dampness; Semen Allii Tuberosi (P1646): function cures mainly: invigorating the liver and kidney, warm waist knee joint, tonifying YANG controlling nocturnal emission with astringent drugs; Nidus Vespae (P2736): function cures mainly: dispel the wind merit poison, parasite killing; Radix Angelicae Sinensis (P876): function cures mainly: benefiting blood and regulating blood circulation, and menstruction regulating and pain relieving is moisturized laxation; Flos Caryophylli (P13): function cures mainly: warming middle-JIAO, warming the kidney, sending down the abnormal ascending QI; Cortex Cinnamomi (P890): function cures mainly: complement sun, warming the spleen and stomach, removing accumulated cold, promoting blood circulation; Air Bladder pseudosciaenae seu Acipenser (P1436): function cures mainly: the kidney invigorating and essence nourishing, nourish the muscle arteries and veins, hemostasis, dissipating blood stasis, detumescence; Gecko (P2376): function cures mainly: invigorating the lung and the kidney, Dingchuan antitussive; Semen Cuscutae (P2006): function cures mainly: invigorating the liver and kidney, beneficial marrow makes eye bright.
Drug component consumption of the present invention is that the following weight parts scope all has better curative effect:
0.5~2 part of Scolopendra, 5~20 parts of Nidus Vespaes, 5~20 parts of Radix Angelicae Sinensis, 5~20 parts of Radix Polygoni Multiflori, 2~10 parts of Flos Caryophyllis, 2~10 parts of Cortex Cinnamomis, 1~5 part in Fructus Piperis, 2~10 parts in Air Bladder pseudosciaenae seu Acipenser.
Be preferably: 1 part of Scolopendra, 7.5 parts of Nidus Vespaes, 10 parts of Radix Angelicae Sinensis, 10 parts of Radix Polygoni Multiflori, 5 parts of Flos Caryophyllis, 5 parts of Cortex Cinnamomis, 2.5 parts in Fructus Piperis, 5 parts in Air Bladder pseudosciaenae seu Acipenser.
Each amounts of components of crude drug of the present invention can also be: 0.5~2 part of Scolopendra, 5~20 parts of Nidus Vespaes, 5~20 parts of Radix Angelicae Sinensis, 5~20 parts of Radix Polygoni Multiflori, 2~10 parts of Flos Caryophyllis, 2~10 parts of Cortex Cinnamomis, 1~5 part in Fructus Piperis, 2~10 parts in Air Bladder pseudosciaenae seu Acipenser, 2~10 parts of the Radix Aucklandiae, 5~20 parts of Semen Ziziphi Spinosaes.
Be preferably: 1 part of Scolopendra, 7.5 parts of Nidus Vespaes, 10 parts of Radix Angelicae Sinensis, 10 parts of Radix Polygoni Multiflori, 5 parts of Flos Caryophyllis, 5 parts of Cortex Cinnamomis, 2.5 parts in Fructus Piperis, 5 parts in Air Bladder pseudosciaenae seu Acipenser, 5 parts of the Radix Aucklandiae, 10 parts of Semen Ziziphi Spinosaes.
Each amounts of components of crude drug of the present invention can also be: 0.5~2 part of Scolopendra, 5~20 parts of Nidus Vespaes, 5~20 parts of Radix Angelicae Sinensis, 5~20 parts of Radix Polygoni Multiflori, 2~10 parts of Flos Caryophyllis, 2~10 parts of Cortex Cinnamomis, 1~5 part in Fructus Piperis, 2~10 parts in Air Bladder pseudosciaenae seu Acipenser, 2~10 parts of the Radix Aucklandiae, 5~20 parts of Semen Ziziphi Spinosaes, 10~30 parts of Herba Epimedii, 5~20 parts of Semen Allii Tuberosi, 5~20 parts of Semen Cuscutae, 30~80 parts of Geckos.
Be preferably: 1 part of Scolopendra, 7.5 parts of Nidus Vespaes, 10 parts of Radix Angelicae Sinensis, 10 parts of Radix Polygoni Multiflori, 5 parts of Flos Caryophyllis, 5 parts of Cortex Cinnamomis, 2.5 parts in Fructus Piperis, 5 parts in Air Bladder pseudosciaenae seu Acipenser, 5 parts of the Radix Aucklandiae, 10 parts of Semen Ziziphi Spinosaes, 15 parts of Herba Epimedii, 10 parts of Semen Allii Tuberosi, 10 parts of Semen Cuscutae, 50 parts of Geckos.
Preparation technology uses " specification requirement of new Chinese medicine Study on Preparation " in principle, the effective constituent that mainly contains that uses modern preparation new technique to extract medicine is used as medicine, add some accessory substances,, can be made into capsule, granule, tablet, oral liquid as water, sugar, starch etc.
The Chinese medicine composition dosage form is as capsule, every day three times, each 5~6 (look the state of an illness, follow the doctor's advice), ten days is a course of treatment, reach rehabilitation effect 1~2 course of treatment substantially, again 1~2 course of treatment of after treatment, can reach the clinical cure effect.
Medicine of the present invention is made capsule and is conveniently taken, and sexual function improving makes erection strong fast, improves the energy of sperm, improves the survival rate of Necrospermia, reaches sexual function improving, makes the physiological function of human body be resumed treatment purpose comprehensively.
The specific embodiment
The present invention is described further by clinical observation test and embodiment.
Test example 1, clinical observation on the therapeutic effect data
1, clinical physical data:
Receive smelting patient 298 examples altogether, wherein the age: 42 examples below 30 years old, 30~35 years old 45 example, 35~40 years old 58 example, 40~45 years old 63 example, 90 examples more than 45 years old; The oldest 53 years old, minimum 20 years old of age; Newly-married 50 examples, 1~2 year marriageable age, 39 examples, 2~3 years marriageable ages, 60 examples, marriageable age is 149 examples more than 3 years, before the treatment course of disease 3 months with interior 68 examples, 3~9 months 75 examples, 9~18 months 46 examples, 109 examples more than 18 months.
2, diagnostic criteria:
The traditional Chinese medical science belongs to kidney yang loss, deficiency of kidney yin etc. to the understanding of primary disease more.Kidney yang is only represented function, and kidney yin is only material base, can not only notice presentation, and ignored the essence of disease, gold dollar four everybody one of Zhu Danxi (traditional Chinese medical science has the saying of " miscellaneous diseases ancestor Dan Xi "), even the judgement of " YANG often being in excess; YIN often being in shortage " is proposed, being not difficult to find out that by above many-side the hepatic and renal YIN deficiency not only meets clinical also realistic, is the basic of functional impotence treatment.
3, Therapeutic Method:
According to the etiology and pathogenesis of sexual dysfunction, it is capsule that treatment becomes the dosage form of compositions with main medication preparation; " the handicapped Chinese medicine composition of a kind of therapeutic " with inventor comrade Wang Qiuru is base side, each crude drug is mainly by Scolopendra, Nidus Vespae, Semen Ziziphi Spinosae, Radix Angelicae Sinensis, Radix Polygoni Multiflori, Flos Caryophylli, the Radix Aucklandiae, Cortex Cinnamomi, Fructus Piperis, Air Bladder pseudosciaenae seu Acipenser is formed, its each composition weight portion is: 0.5~2 part of Scolopendra, 5~20 parts of Nidus Vespaes, 5~20 parts of Semen Ziziphi Spinosaes, 5~20 parts of Radix Angelicae Sinensis, 5~20 parts of Radix Polygoni Multiflori, 2~10 parts of Flos Caryophyllis, 2~10 parts of the Radix Aucklandiae, 2~10 parts of Cortex Cinnamomis, 1~5 part in Fructus Piperis, 2~10 parts in Air Bladder pseudosciaenae seu Acipenser, crude drug also can add 10~30 parts of Herba Epimedii, 5~20 parts of Semen Allii Tuberosi, 5~20 parts of Semen Cuscutae, 30~80 parts of Geckos are adopted preferred side during use.
The Chinese medicine composition dosage form is as capsule, usage every day three times, each 5~6 (look the state of an illness, follow the doctor's advice), ten days is a course of treatment, reach rehabilitation effect 1~2 course of treatment substantially, again 1~2 course of treatment of after treatment, can reach the clinical cure effect.
4, efficacy assessment standard:
Recovery from illness: clinical symptom disappearance, sexual life, vital essence recover normal, and sperm existence and survival rate are normal.
Produce effects: clinical symptoms alleviates substantially or obviously, and sexual life, vital essence significantly strengthen, and sperm survival rate increases.
Take a turn for the better: subjective symptoms disappears or significantly alleviates, and spirit, vital essence are clearly better.
Invalid: 2 of medications are more than the course of treatment, and symptom does not have obvious improvement; Each index does not have obvious change.
5, therapeutic outcome:
By the conventional therapy of 1~2 course of treatment, can improve clinical symptoms rapidly: recovery from illness: 132 examples, account for 44.3%, produce effects 61 examples, account for 20.5%, 35 examples that take a turn for the better, account for 11.7%, invalid 70 examples, account for 23.5%; Total effective rate 76.5%.
Through 1~2 after treatment course of treatment, clinical symptoms rapidly disappears, body constitution recovers normal again; Recovery from illness: 168 examples, account for 56.4%, produce effects 72 examples, account for 24.2%, 42 examples that take a turn for the better, account for 14.1%, invalid 16 examples, account for 5.3%; Total effective rate 94.7%.
Embodiment 1: the preparation of capsule formulation of the present invention
Getting each composition bulk drugs is: 1 part of Scolopendra, 7.5 parts of Nidus Vespaes, 10 parts of Radix Angelicae Sinensis, 10 parts of Radix Polygoni Multiflori, 5 parts of Flos Caryophyllis, 5 parts of Cortex Cinnamomis, 2.5 parts in Fructus Piperis, 5 parts in Air Bladder pseudosciaenae seu Acipenser.
Embodiment 2: add 5 parts of the Radix Aucklandiae, 10 parts of Semen Ziziphi Spinosaes on the basis of embodiment 1.
Embodiment 3: add 15 parts of Herba Epimedii, 10 parts of Semen Allii Tuberosi, 10 parts of Semen Cuscutae, 50 parts of Geckos on the basis of embodiment 2.
Preparation technology meets " specification requirement of new Chinese medicine Study on Preparation " in principle, uses modern preparation new technique, said medicine is dried be crushed to more than 100 orders, incapsulates in the clothing, makes capsule.
Embodiment 4: the preparation of granule dosage form of the present invention
Getting each composition bulk drugs is: 1 part of Scolopendra, 7.5 parts of Nidus Vespaes, 10 parts of Radix Angelicae Sinensis, 10 parts of Radix Polygoni Multiflori, 5 parts of Flos Caryophyllis, 5 parts of Cortex Cinnamomis, 2.5 parts in Fructus Piperis, 5 parts in Air Bladder pseudosciaenae seu Acipenser.
Embodiment 5: add 5 parts of the Radix Aucklandiae, 10 parts of Semen Ziziphi Spinosaes on the basis of embodiment 4.
Embodiment 6: add 15 parts of Herba Epimedii, 10 parts of Semen Allii Tuberosi, 10 parts of Semen Cuscutae, 50 parts of Geckos on the basis of embodiment 5.
Preparation technology meets " specification requirement of new Chinese medicine Study on Preparation " in principle, uses modern preparation new technique, said medicine is dried be crushed to more than 100 orders, adds some accessory substances, the preparation granule.

Claims (6)

1, the handicapped Chinese medicine composition of a kind of therapeutic is characterized in that it mainly is to be made by following bulk drugs: 0.5~2 part of Scolopendra, 5~20 parts of Nidus Vespaes, 5~20 parts of Radix Angelicae Sinensis, 5~20 parts of Radix Polygoni Multiflori, 2~10 parts of Flos Caryophyllis, 2~10 parts of Cortex Cinnamomis, 1~5 part in Fructus Piperis, 2~10 parts in Air Bladder pseudosciaenae seu Acipenser.
2, the handicapped Chinese medicine composition of a kind of therapeutic according to claim 1 is characterized in that wherein the consumption of crude drug is: 1 part of Scolopendra, 7.5 parts of Nidus Vespaes, 10 parts of Radix Angelicae Sinensis, 10 parts of Radix Polygoni Multiflori, 5 parts of Flos Caryophyllis, 5 parts of Cortex Cinnamomis, 2.5 parts in Fructus Piperis, 5 parts in Air Bladder pseudosciaenae seu Acipenser.
3, the handicapped Chinese medicine composition of a kind of therapeutic according to claim 1 is characterized in that wherein crude drug also has: 2~10 parts of the Radix Aucklandiae, 5~20 parts of Semen Ziziphi Spinosaes.
4, the handicapped Chinese medicine composition of a kind of therapeutic according to claim 3, it is characterized in that wherein the consumption of each component is: 1 part of Scolopendra, 7.5 parts of Nidus Vespaes, 10 parts of Radix Angelicae Sinensis, 10 parts of Radix Polygoni Multiflori, 5 parts of Flos Caryophyllis, 5 parts of Cortex Cinnamomis, 2.5 parts in Fructus Piperis, 5 parts in Air Bladder pseudosciaenae seu Acipenser, 5 parts of the Radix Aucklandiae, 10 parts of Semen Ziziphi Spinosaes.
5, the handicapped Chinese medicine composition of a kind of therapeutic according to claim 3 is characterized in that wherein crude drug also has: 10~30 parts of Herba Epimedii, 5~20 parts of Semen Allii Tuberosi, 5~20 parts of Semen Cuscutae, 30~80 parts of Geckos.
6, the handicapped Chinese medicine composition of a kind of therapeutic according to claim 5, it is characterized in that wherein the consumption of each component is: 1 part of Scolopendra, 7.5 parts of Nidus Vespaes, 10 parts of Radix Angelicae Sinensis, 10 parts of Radix Polygoni Multiflori, 5 parts of Flos Caryophyllis, 5 parts of Cortex Cinnamomis, 2.5 parts in Fructus Piperis, 5 parts in Air Bladder pseudosciaenae seu Acipenser, 5 parts of the Radix Aucklandiae, 10 parts of Semen Ziziphi Spinosaes, 15 parts of Herba Epimedii, 10 parts of Semen Allii Tuberosi, 10 parts of Semen Cuscutae, 50 parts of Geckos.
CN 200410012753 2004-02-18 2004-02-18 Chinese medicinal composition for treating sexual dysfunction Expired - Fee Related CN1275618C (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101167879B (en) * 2007-11-08 2010-10-13 金城 Preparation for increasing erection rigidity and prolonging intercourse endurance and condom containing the same
CN106177254A (en) * 2016-08-30 2016-12-07 商共朝 A kind of pharmaceutical composition treating sexual impotence
US10383910B2 (en) 2016-04-27 2019-08-20 King Abdulaziz University Methods of increasing fertility of a male subject with costus speciosus extract

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101167879B (en) * 2007-11-08 2010-10-13 金城 Preparation for increasing erection rigidity and prolonging intercourse endurance and condom containing the same
US10383910B2 (en) 2016-04-27 2019-08-20 King Abdulaziz University Methods of increasing fertility of a male subject with costus speciosus extract
CN106177254A (en) * 2016-08-30 2016-12-07 商共朝 A kind of pharmaceutical composition treating sexual impotence

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