CN101167879B - Preparation for increasing erection rigidity and prolonging intercourse endurance and condom containing the same - Google Patents
Preparation for increasing erection rigidity and prolonging intercourse endurance and condom containing the same Download PDFInfo
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- CN101167879B CN101167879B CN2007101580042A CN200710158004A CN101167879B CN 101167879 B CN101167879 B CN 101167879B CN 2007101580042 A CN2007101580042 A CN 2007101580042A CN 200710158004 A CN200710158004 A CN 200710158004A CN 101167879 B CN101167879 B CN 101167879B
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Abstract
The invention relates to a medicament for increasing erectile hardness and prolonging coital persistency, and a condom which contains the medicament. Raw material combination is that 5 to 10g diclothane, 5 to 10g dicaine, 0.04 to 0.1g prostaglandin E1, 5 to 20g laurocapram, 10 to 20g phentolamine mesylate, 10 to 20g secretio bufonis, 25 to 50g cardoverine, 10 to 30g quebrachine, and eight crude medicine such as panax ginseng crude drug, barren wort crude drug, Sichuan aconite root crude drug, and strychnos nux-vomica crude drug and the like. Matrix is silicone oil or carbomer, the eight crudedrugs such as, the panax ginseng crude drug, the barren wort crude drug, the Sichuan aconite root crude drug, and the strychnos nux-vomica crude drug and the like are made into clear paste. The clearpaste is dissolved into the secretio bufonis, the cardoverine, and the quebrachine, and then the clear paste is uniformly stirred with the diclothane, the dicaine, the prostaglandin E1, the phentolamine mesylate, and the laurocapram. Miscible liquids are slowly added into water to make medicament. The medicament is instilled into condoms to make condoms. The invention has 90 percent effective rate to impotence, which has 99 percent effective rate to premature ejaculation patients and to prolong coital time.
Description
Technical field: the present invention relates to a kind of function preparation, especially add several draft and western medicine composition, can increase erection hardness, prolong the preparation of sexual intercourse endurance and contain the condom of said preparation.
Background technology: at present, the condom of countries in the world, single from contraception, prevent that sexually transmitted disease (STD), infectious disease aspect say that its technological layer is safe and reliable.But condom itself uses when being used for man and wife and men and women's sexual intercourse, is a kind of typical hommization product.But conventional security is enclosed within the hommization demand side exists critical defect, that is: common condom does not possess the function that increases erection hardness and prolong sexual intercourse endurance.Man, women's doubles side can reach good erection hardness, and can prolong sex time as far as possible in sexual life, and can make man, women's doubles side can both reach own desired orgasm and voluptus, and this is the demand of human nature.But common condom does not possess this function.
Summary of the invention: in order to remedy above-mentioned defective, the invention provides a kind ofly can increase erection hardness, prolongs the preparation of sexual intercourse endurance and allow adult male when cover safe in utilization, be improved and increase erection hardness, effectively prolong the condom of the effect of sexual intercourse endurance.
Concrete technical scheme is as follows: increase erection hardness, prolong sexual intercourse endurance preparation, in 500 gram substrate, contain following raw material compatibility by weight, be processed into the preparation finished product after extract:
Dyclonine 5~10 gram tetracaine 5~10 grams
Prostaglandin E
10.04~0.1 gram azone 5~10 grams
Phentolamine mesylate 10~20 gram Venenum Bufoniss 10~20 grams
Papaverine 25~50 gram Yohimbines 20~30 grams
Radix Ginseng crude drug 400~500 gram Herba Epimedii crude drugs 400~500 grams
Radix Aconiti crude drug 400~500 KEMA Semen Strychni crude drugs 400~500 grams
Magnificent Herba Asari crude drug 200~300 grams of Rhizoma Corydalis crude drug 400~500 grams
Radix Stephaniae Tetrandrae crude drug 200~300 gram Flos Daturae crude drugs 100~200 grams
Wherein, substrate is silicone oil, or the carbomer of 1~2 gram is dissolved in the water of 500ml, regulates pH to 6~7 with Borax;
Increase erection hardness, to prolong sexual intercourse endurance formulation preparation method as follows:
1) with above-mentioned Radix Ginseng crude drug, the Herba Epimedii crude drug, Radix Aconiti crude drug, Semen Strychni crude drug, Rhizoma Corydalis crude drug, magnificent Herba Asari crude drug, Radix Stephaniae Tetrandrae crude drug and Flos Daturae crude drug mix, extracting in water 2 times, the first time, 8~10 times of water extraction were 2 hours, the second time, 6~8 times of water extraction were 1.5 hours, merge extracted twice liquid, under 60 ℃ of temperature, be evaporated to the clear paste of relative density 1.2-1.25, add the ethanol of 3 times of amounts 95% of clear paste again, precipitate with ethanol 24 hours, decompression recycling ethanol under 60 ℃ of conditions, is concentrated into relative density 1.15-1.20;
2) Venenum Bufonis, papaverine and Yohimbine are mixed, add 2~4 times water for injection dissolving, with the clear paste mix homogeneously of said extracted concentrated solution, standby;
3) get dyclonine, tetracaine, PGE1, phentolamine mesylate and add the azone stirring and dissolving after, the mixed solution that makes with the 2nd step stirs, mix homogeneously is standby;
4) with the 3rd go on foot mixed liquor slowly join in the substrate of 500g, stir.
Increase erection hardness, prolongation sexual intercourse endurance preparation with said method makes under gnotobasis, add in the condom, and every adds 0.5~1 gram, packs, and can obtain condom of the present invention.
The present invention is through 82 routine anthroposcopy experiment confirms, and this invention possesses the described effect of patent of invention.Concrete experimental technique is as follows:
A. test one
1. select erection disturbance patient 82 examples (the average ill history 2-3 of sexual impotence) between age 45-65 year, providing for earlier every volunteer contrasts with condom (latex company provides by the world, Shenyang), and then play pornofilm for above-mentioned 82 patients, and allow all experimenter's masturbations, observed 15 minutes continuously, above-mentioned 82 philtrums have only 4 people that slight erection is arranged, and other 78 people does not all have erectile response.In addition, there are 6 people to begin ejaculation (the premature ejaculation symptom is arranged) within 3 minutes in masturbation; All the other 76 people all are ejaculations successively after 10 minutes.
2.3 after it, select same above-mentioned 82 volunteers, and issue the condom that adds preparation of the present invention for every experimenter.Under similarity condition, see same pornofilm, the result has 66 people to begin to erect in 2-3 divides; Erect fully in 4-6 minute.Other has 14 people, and 6 minutes begin later on to erect, and erectile condition recovers normal after 10 minutes, and last 2 experimenters fail to erect.Among above-mentioned 82 experimenters, first is to begin ejaculation after 13 minutes in masturbation, and last position is to begin ejaculation after 36 minutes in masturbation, and all the other are to finish the ejaculation action within 20-30 minute per capita.(seeing Table 1)
Table 1 uses the new invention condom front and back erectile condition and the endurance result of variations of consoling oneself
The experimental result prompting: new invention safety is with improves erection hardness, prolongs the effect of sexual intercourse endurance.
B. test two
After three weeks, issue the reference substance condom for equally above-mentioned 82 volunteers, allow itself and sexual's sexual intercourse and selftest erection hardness and sex time.From the record that 82 experimenters return, wherein there are 6 people to exempt from strong erection, but have only 2 people to insert wife's side vagina reluctantly, all the other 76 people all do not have erectile response.
After three days, everyone provides a condom that patent of the present invention is housed to experimental group to above-mentioned 82 experimenters, and allows experimenter oneself record erectile condition and sexual intercourse persistent period.Statistical result shows: among above-mentioned 82 experimenters, 63 safety erections in 2-4 minute are arranged, have 16 people to recover to erect after 5 minutes, above-mentioned 79 people successfully insert vagina with penis.Have only 3 people only to feel that there is the flatulence of heat type sense in penis portion, but fail safe erection.Above-mentioned 79 erection winners, its time of ejaculation the earliest is 17 minutes, the ejaculator is 33 minutes at the latest.The average ejaculation time is about 20-25 minute.(seeing Table 2)
Table 2 uses new invention condom front and back erectile condition and sexual intercourse endurance result of variations
The experimental result prompting: the new type of safe of this invention is with the good erection hardness that improves, and effectively prolongs the effect of sexual intercourse endurance.
The invention has the beneficial effects as follows: human experimentation confirms: this invention is about 88-90% to various sexual impotence (ED) total effective rate, effective percentage to premature ejaculation patient and prolongation sex time reaches about 98-99%, and because of medicine for external use dosage few, the topical transdermal good absorbing effect is so reduced to minimum to the side effect of human body.
The specific embodiment:
Embodiment 1
Increase erection hardness, prolong sexual intercourse endurance preparation,, contain following raw material compatibility by weight, be processed into the preparation finished product after extract in 500 gram substrate:
Dyclonine 5 gram tetracaine 5 grams
PGE1 0.04 gram azone 5 grams
Phentolamine mesylate 10 gram Venenum Bufoniss 10 grams
Papaverine 25 gram Yohimbines 20 grams
Radix Ginseng crude drug 400 gram Herba Epimedii crude drugs 400 grams
Radix Aconiti crude drug 400 KEMA Semen Strychni crude drugs 400 grams
Magnificent Herba Asari crude drug 200 grams of Rhizoma Corydalis crude drug 400 grams
Radix Stephaniae Tetrandrae crude drug 200 gram Flos Daturae crude drugs 100 grams
Wherein, substrate is silicone oil;
Increase erection hardness, to prolong sexual intercourse endurance formulation preparation method as follows:
1) with above-mentioned Radix Ginseng crude drug, the Herba Epimedii crude drug, Radix Aconiti crude drug, Semen Strychni crude drug, Rhizoma Corydalis crude drug, magnificent Herba Asari crude drug, Radix Stephaniae Tetrandrae crude drug and Flos Daturae crude drug mix, extracting in water 2 times, the first time, 8 times of water extraction were 2 hours, the second time, 6 times of water extraction were 1.5 hours, merge extracted twice liquid, under 60 ℃ of temperature, be evaporated to the clear paste of relative density 1.2-1.25, add the ethanol of 3 times of amounts 95% of clear paste again, precipitate with ethanol 24 hours, decompression recycling ethanol under 60 ℃ of conditions, is concentrated into relative density 1.15-1.20;
2) Venenum Bufonis, papaverine and Yohimbine are mixed, add 2 times water for injection dissolving, with the clear paste mix homogeneously of said extracted concentrated solution, standby;
3) get dyclonine, tetracaine, PGE1, phentolamine mesylate and add the azone stirring and dissolving after, the mixed solution that makes with the 2nd step stirs, mix homogeneously is standby;
4) with the 3rd go on foot mixed liquor slowly join in the substrate of 500g, stir.
Embodiment 2
Increase erection hardness, prolong sexual intercourse endurance preparation,, contain following raw material compatibility by weight, be processed into the preparation finished product after extract in 500 gram substrate:
Dyclonine 8 gram tetracaine 8 grams
Prostaglandin E
10.08 gram azone 8 grams
Phentolamine mesylate 15 gram Venenum Bufoniss 15 grams
Papaverine 35 gram Yohimbines 25 grams
Radix Ginseng crude drug 450 gram Herba Epimedii crude drugs 450 grams
Radix Aconiti crude drug 450 KEMA Semen Strychni crude drugs 450 grams
Magnificent Herba Asari crude drug 250 grams of Rhizoma Corydalis crude drug 450 grams
Radix Stephaniae Tetrandrae crude drug 250 gram Flos Daturae crude drugs 150 grams
Wherein, substrate is that 1 carbomer that restrains is dissolved in the water of 500ml, regulates pH to 6.5 with Borax;
Increase erection hardness, to prolong sexual intercourse endurance formulation preparation method as follows:
1) with above-mentioned Radix Ginseng crude drug, the Herba Epimedii crude drug, Radix Aconiti crude drug, Semen Strychni crude drug, Rhizoma Corydalis crude drug, magnificent Herba Asari crude drug, Radix Stephaniae Tetrandrae crude drug and Flos Daturae crude drug mix, extracting in water 2 times, the first time, 9 times of water extraction were 2 hours, the second time, 7 times of water extraction were 1.5 hours, merge extracted twice liquid, under 60 ℃ of temperature, be evaporated to the clear paste of relative density 1.2-1.25, add the ethanol of 3 times of amounts 95% of clear paste again, precipitate with ethanol 24 hours, decompression recycling ethanol under 60 ℃ of conditions, is concentrated into relative density 1.15-1.20;
2) Venenum Bufonis, papaverine and Yohimbine are mixed, add 3 times water for injection dissolving, with the clear paste mix homogeneously of said extracted concentrated solution, standby;
3) get dyclonine, tetracaine, PGE1, phentolamine mesylate and add the azone stirring and dissolving after, the mixed solution that makes with the 2nd step stirs, mix homogeneously is standby;
4) with the 3rd go on foot mixed liquor slowly join in the substrate of 500g, stir.
Embodiment 3
Increase erection hardness, prolong sexual intercourse endurance preparation, it is characterized in that containing following raw material compatibility by weight, be processed into the preparation finished product after extract in 500 gram substrate:
Dyclonine 10 gram tetracaine 10 grams
Prostaglandin E
10.1 gram azone 10 grams
Phentolamine mesylate 20 gram Venenum Bufoniss 20 grams
Papaverine 50 gram Yohimbines 30 grams
Radix Ginseng crude drug 500 gram Herba Epimedii crude drugs 500 grams
Radix Aconiti crude drug 500 KEMA Semen Strychni crude drugs 500 grams
Magnificent Herba Asari crude drug 300 grams of Rhizoma Corydalis crude drug 500 grams
Radix Stephaniae Tetrandrae crude drug 300 gram Flos Daturae crude drugs 200 grams
Wherein, substrate is that 2 carbomers that restrain are dissolved in the water of 500ml, regulates pH to 7 with Borax;
Increase erection hardness, to prolong sexual intercourse endurance formulation preparation method as follows:
1) with above-mentioned Radix Ginseng crude drug, the Herba Epimedii crude drug, Radix Aconiti crude drug, Semen Strychni crude drug Rhizoma Corydalis crude drug, magnificent Herba Asari crude drug, Radix Stephaniae Tetrandrae crude drug and Flos Daturae crude drug mix, extracting in water 2 times, the first time, 10 times of water extraction were 2 hours, the second time, 8 times of water extraction were 1.5 hours, merge extracted twice liquid, under 60 ℃ of temperature, be evaporated to the clear paste of relative density 1.2-1.25, add the ethanol of 3 times of amounts 95% of clear paste again, precipitate with ethanol 24 hours, decompression recycling ethanol under 60 ℃ of conditions, is concentrated into relative density 1.15-1.20;
2) Venenum Bufonis, papaverine and Yohimbine are mixed, add 4 times water for injection dissolving, with the clear paste mix homogeneously of said extracted concentrated solution, standby;
3) get dyclonine, tetracaine, PGE1, phentolamine mesylate and add the azone stirring and dissolving after, the mixed solution that makes with the 2nd step stirs, mix homogeneously is standby;
4) with the 3rd go on foot mixed liquor slowly join in the substrate of 500g, stir.
Embodiment 4
The increase erection hardness that embodiment 1, embodiment 2 or embodiment 3 are obtained, prolong sexual intercourse endurance preparation, in gnotobasis, pharmaceutical preparation is dripped in the condom, make respectively and only contain preparation 0.5g/, 0.8g/ only, 1.0g/ only, pack, promptly get condom of the present invention.
Claims (2)
1. increase erection hardness, prolong sexual intercourse endurance preparation, it is characterized in that,, be processed into the preparation finished product after extract by following raw material compatibility by weight in 500 gram substrate:
Dyclonine 5~10 gram tetracaine 5~10 grams
Prostaglandin E
10.04~0.1 gram azone 5~10 grams
Phentolamine mesylate 10~20 gram Venenum Bufoniss 10~20 grams
Papaverine 25~50 gram Yohimbines 20~30 grams
Radix Ginseng crude drug 400~500 gram Herba Epimedii crude drugs 400~500 grams
Radix Aconiti crude drug 400~500 KEMA Semen Strychni crude drugs 400~500 grams
Magnificent Herba Asari crude drug 200~300 grams of Rhizoma Corydalis crude drug 400~500 grams
Radix Stephaniae Tetrandrae crude drug 200~300 gram Flos Daturae crude drugs 100~200 grams
Wherein, substrate is silicone oil, or the carbomer of 1~2 gram is dissolved in the water of 500ml, regulates pH to 6~7 with Borax;
Increase erection hardness, to prolong sexual intercourse endurance formulation preparation method as follows:
1) with above-mentioned Radix Ginseng crude drug, the Herba Epimedii crude drug, Radix Aconiti crude drug, Semen Strychni crude drug, Rhizoma Corydalis crude drug, magnificent Herba Asari crude drug, Radix Stephaniae Tetrandrae crude drug and Flos Daturae crude drug mix, extracting in water 2 times, the first time, 8~10 times of water extraction were 2 hours, the second time, 6~8 times of water extraction were 1.5 hours, merge extracted twice liquid, under 60 ℃ of temperature, be evaporated to the clear paste of relative density 1.2-1.25, add the ethanol of 3 times of amounts 95% of clear paste again, precipitate with ethanol 24 hours, decompression recycling ethanol under 60 ℃ of conditions, is concentrated into relative density 1.15-1.20;
2) Venenum Bufonis, papaverine and Yohimbine are mixed, add 2~4 times water for injection dissolving, with the clear paste mix homogeneously of said extracted concentrated solution, standby;
3) get dyclonine, tetracaine, PGE1, phentolamine mesylate and add the azone stirring and dissolving after, the mixed solution that makes with the 2nd step stirs, mix homogeneously is standby;
4) with the 3rd go on foot mixed liquor slowly join in the substrate of 500g, stir.
2. a condom is characterized in that the described increase erection hardness of claim 1, prolongs sexual intercourse endurance preparation, under gnotobasis, adds in the condom, and every adds 0.5~1 gram.
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CN2007101580042A CN101167879B (en) | 2007-11-08 | 2007-11-08 | Preparation for increasing erection rigidity and prolonging intercourse endurance and condom containing the same |
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CN2007101580042A CN101167879B (en) | 2007-11-08 | 2007-11-08 | Preparation for increasing erection rigidity and prolonging intercourse endurance and condom containing the same |
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CN101167879A CN101167879A (en) | 2008-04-30 |
CN101167879B true CN101167879B (en) | 2010-10-13 |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108938176A (en) * | 2018-08-03 | 2018-12-07 | 孙廷柱 | A kind of soluble condom and its production method promoting sexual function |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
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CN101422570B (en) * | 2008-12-08 | 2011-09-28 | 济南老来寿生物股份有限公司 | Functional food capable of increasing male sexual function |
CN103479463A (en) * | 2013-09-25 | 2014-01-01 | 桂林恒保健康用品有限公司 | Condom for treating impotence and premature ejaculation |
CN112999156B (en) * | 2021-03-03 | 2023-09-08 | 宁波御坊堂生物科技有限公司 | Erection-assisting time-delay essential oil spray with synergistic yohimbine hydrochloride and preparation method thereof |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1113757A (en) * | 1994-06-24 | 1995-12-27 | 王儒新 | Sexual function improving agent and its preparing method |
CN1326748A (en) * | 2001-06-02 | 2001-12-19 | 辛耀禄 | Tincture for curing male's sexual function disturbance and its preparing process |
CN1559502A (en) * | 2004-02-18 | 2005-01-05 | 王秋如 | Chinese medicinal composition for treating sexual dysfunction |
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2007
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Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1113757A (en) * | 1994-06-24 | 1995-12-27 | 王儒新 | Sexual function improving agent and its preparing method |
CN1326748A (en) * | 2001-06-02 | 2001-12-19 | 辛耀禄 | Tincture for curing male's sexual function disturbance and its preparing process |
CN1559502A (en) * | 2004-02-18 | 2005-01-05 | 王秋如 | Chinese medicinal composition for treating sexual dysfunction |
Non-Patent Citations (1)
Title |
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CN 1559502 A,全文. |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108938176A (en) * | 2018-08-03 | 2018-12-07 | 孙廷柱 | A kind of soluble condom and its production method promoting sexual function |
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