CN1557454A - Medicinal composition for treating psoriasis and preparation method thereof - Google Patents
Medicinal composition for treating psoriasis and preparation method thereof Download PDFInfo
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- CN1557454A CN1557454A CNA2004100391073A CN200410039107A CN1557454A CN 1557454 A CN1557454 A CN 1557454A CN A2004100391073 A CNA2004100391073 A CN A2004100391073A CN 200410039107 A CN200410039107 A CN 200410039107A CN 1557454 A CN1557454 A CN 1557454A
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Abstract
The medicine composition for treating psoriasis is prepared with roasted black tail snake, scorpion, buffalo horn, smilax glabra rhizome, rhubarb and other Chinese medicinal materials. The preparation process includes grinding partial Chinese medicinal materials into coarse powder, decocting the other Chinese medicinal materials, precipitating the medicine decoction to obtain the supernatant, concentrating the supernatant into ointment, mixing the coarse powder and the ointment, drying the mixture, grinding the mixture into fine powder and capsulizing. The medicine is clinically safe, and has high curative rate, no toxic side effect and low recurrence rate.
Description
Technical field
The present invention relates to a kind of pharmaceutical composition, particularly relate to the psoriatic Chinese medicine composition and method of making the same of a kind of treatment.
Background technology
The psoriasis traditional Chinese medical science claims psoriasis, and old young men and women all can be ill, but is many with the male adults patient.And certain genetic predisposition is arranged, and morbidity has obvious seasonal, and many winters, spring increase the weight of, and alleviate summer or spontaneous recovery.This disease etiology and pathology is comparatively complicated, many and heat in blood, blood be dry have closely related.The phase of carrying out: how because of feelings will internal injury, obstruction of QI, strongly fragrant heat-transformation of a specified duration and send out; Hyperactivity of heart-fire, scorchingly hot lying prostrate in nutrient blood sent out; Intemperance of taking food, the pungent wine of surfeit is wet, the product of fish raw meat stimulating food, wind symptom, and taste are become estranged, functional activity of QI being not smooth, strongly fragrant heat-transformation of a specified duration is accumulate and is amassed that to feel wind heat poison again in skin evil and send out, and it shows as the skin lesion development soon, pruritus, color is red, and patient's red tongue with thin and yellow fur constantly appears in new rash, dry mouth and tougue, susceptible to lose temper due to restlessness, dry stool yellow urine, wiry and frequent pulse or sliding number are waited the dryness-transformation of intenseness of heat impairment of YIN outside one heat in blood, so card is seen white scales, dry stool, yellow urine.Resting stage: disease is outbreak repeatedly for a long time, and cloudy blood is consumed, and is qi-blood disharmony, living wind of dryness-transformation or passages through which vital energy circulates retardance, and QI and blood is lost fortune, and skin loses to moisten foster and arrives, and waits outside one blood-deficiency and wind-dry.Patient table has xerosis cutis now, and the erythra color is light, desquamation, Tianjin anemia void can not on hold then xerostomia dry pharynx, dizziness and blurred vision, complexion is turned white, the few tongue of light red tongue, soft and thready pulse.
Technology contents
The object of the present invention is to provide a kind of pharmaceutical composition that the treatment psoriasis is had remarkable result.
Another object of the present invention is to provide a kind of treatment psoriatic preparation of drug combination method.
The present invention is achieved through the following technical solutions:
Choose crude drug:
Process Zaocys 10-50 weight portion Scorpio 10-50 weight parts water Cornu Bovis seu Bubali 50-100 weight portion
Rhizoma Smilacis Glabrae 30-150 weight portion Radix Et Rhizoma Rhei 6-20 weight portion Flos Sophorae Immaturus 15-60 weight portion
Radix Clerodenri Cyrtophylli 30-60 weight portion Radix Angelicae Sinensis 15-50 weight portion Radix Glycyrrhizae 6-15 weight portion
Caulis Spatholobi 30-60 weight portion
Optimum ratio of the present invention is:
Process Zaocys 30 weight portion Scorpios 30 weight parts water Cornu Boviss seu Bubali 75 weight portions
The Rhizoma Smilacis Glabrae 90 weight portion Radix Et Rhizoma Rhei 13 weight portion Flos Sophorae Immaturus 40 weight portions
Radix Clerodenri Cyrtophylli 45 weight portion Radix Angelicae Sinensis 30 weight portion Radix Glycyrrhizaes 10 weight portions
Caulis Spatholobi 45 weight portions
The present composition adds pharmaceutically acceptable conventional adjuvant and makes clinical acceptable forms, as capsule, tablet, granule, oral liquid, drop pill, pill, powder, injection etc.
Preparation method of the present invention for will process Zaocys, Scorpio, Radix Et Rhizoma Rhei, the Flos Sophorae Immaturus, Radix Angelicae Sinensis, Radix Glycyrrhizae altogether powder become coarse powder standby; Again Rhizoma Smilacis Glabrae, Caulis Spatholobi, Cornu Bubali, Radix Clerodenri Cyrtophylli decocting are extracted 2-4 time, the taking liquid precipitation was collected clear liquor after 2-6 hour, was condensed into cream, add and to process Zaocys, Scorpio, Radix Et Rhizoma Rhei, the Flos Sophorae Immaturus, Radix Angelicae Sinensis, Radix Glycyrrhizae coarse powder and mix thoroughly, dry back powder is that fine powder is made capsule.
Following experimental example is used to further specify the present invention.
Clinical data: the present composition is divided into the phases of carrying out 259 example from general property psoriasis 726 examples of treatment in nineteen ninety-five-2002 end of the year by simplifying typing, resting stages 467 example; Man's 528 examples, women 198 examples, maximum 62 years old age, minimum 17 years old, wherein 20-40 year 589 examples.The course of disease 1 year accounts for more than 22.2%, one year with interior person's 161 examples and accounted for that person's 157 examples account for 21.6% more than 56.2%, six year in 6 years with interior person's 408 examples.
Side's medicine preparation and application: process Zaocys 30g, Scorpio 30g, Cornu Bubali 75g, Radix Et Rhizoma Rhei 13g, Flos Sophorae Immaturus 40g, Caulis Spatholobi 45g, Rhizoma Smilacis Glabrae 90g, Radix Clerodenri Cyrtophylli 45g, Radix Angelicae Sinensis 30g, Radix Glycyrrhizae 10g powder and fine powder altogether, dress No. zero (0.5 gram/grain) capsule.3 of each clothes, every day 3 times, every month is a course of treatment.
Curative effect judging standard:
Cure: the whole body skin lesion not recidivist of all disappearing more than a year.
Produce effects: the whole body skin lesion all disappears, and drug withdrawal had the recidivist in 1 year.
Effectively: the 1-3 skin lesion course of treatment of taking medicine has minimizing in various degree, and 4-5 still can not disappear the course of treatment fully.
Invalid: as to obey 3 skin lesion course of treatment alleviators not.
Therapeutic outcome: see the following form
Conclusion: present composition treatment psoriasis 726 examples, treatment rate is 86%, total effective rate 98%, its great advantage is not aviod certain food, not medicine for external use.Take medicine the shortest two courses of treatment the longest five courses of treatment.Through clinical practice safely, have no side effect, cure rate height, relapse rate are low.
Model case: Xu so-and-so, man 34 years old, peasant, general psoriasis (psoriasis) 8 years.Have a medical check-up as seen: back such as map shape, extremity are the patch shape, and skin lesion place basilar part is light red, and scrape off squama and be sieve shape oozing of blood point, be many with anterior hair line between sending out, little itching, stringy and rolling pulse, red tongue with thin fur is white, and stool does sometimes.Diagnosis; Psoriasis (resting stage).Clothes present composition capsule, each 3, every day 3 times, taking medicine after meal.The obvious attenuation of skin lesion squama after the course of treatment, the squama major part disappears after two courses of treatment, and it is light that erythema is changeed, only surplus duplex, back, the meagre squama of anterior hair line fraction after three courses of treatment, the skin full recovery is normal after four courses of treatment.Due to illness the people is very satisfied, requires to consolidate two months again, and following up a case by regular visits in 6 years so far after the drug withdrawal does not have recurrence.
Embodiment 1:
Process Zaocys 30 gram Scorpios 30 gram Cornu Bubalis 75 grams
The Rhizoma Smilacis Glabrae 90 gram Radix Et Rhizoma Rhei 13 gram Flos Sophorae Immaturus 40 grams
Radix Clerodenri Cyrtophylli 45 gram Radix Angelicae Sinensis 30 gram Radix Glycyrrhizaes 10 grams
Caulis Spatholobi 45 grams
To process Zaocys, Scorpio, Radix Et Rhizoma Rhei, the Flos Sophorae Immaturus, Radix Angelicae Sinensis, Radix Glycyrrhizae altogether powder become coarse powder standby; Rhizoma Smilacis Glabrae, Caulis Spatholobi, Cornu Bubali, Radix Clerodenri Cyrtophylli decocting are extracted 3 times, the taking liquid precipitation was collected clear liquor after 4 hours, was condensed into cream again, added to process Zaocys, Scorpio, Radix Et Rhizoma Rhei, the Flos Sophorae Immaturus, Radix Angelicae Sinensis, Radix Glycyrrhizae coarse powder and mix thoroughly, and dry back powder is a fine powder dress zero capsule.Every 0.5 gram, 100 every bottle.Every day 3 times, obey 3 at every turn, be a course of treatment January.
Embodiment 2:
Process Zaocys 10 gram Scorpios 10 gram Cornu Bubalis 50 grams
The Rhizoma Smilacis Glabrae 30 gram Radix Et Rhizoma Rhei 6 gram Flos Sophorae Immaturus 15 grams
Radix Clerodenri Cyrtophylli 30 gram Radix Angelicae Sinensis 15 gram Radix Glycyrrhizaes 6 grams
Caulis Spatholobi 30 grams
Said medicine technology is routinely made tablet.
Embodiment 3:
Process Zaocys 50 gram Scorpios 50 gram Cornu Bubalis 100 grams
The Rhizoma Smilacis Glabrae 150 gram Radix Et Rhizoma Rhei 20 gram Flos Sophorae Immaturus 60 grams
Radix Clerodenri Cyrtophylli 60 gram Radix Angelicae Sinensis 50 gram Radix Glycyrrhizaes 15 grams
Caulis Spatholobi 60 grams
Said medicine technology is routinely made a material agent.
Claims (4)
1, the psoriatic pharmaceutical composition of a kind of treatment is characterized in that said composition mainly made by following crude drug:
Process Zaocys 10-50 weight portion Scorpio 10-50 weight parts water Cornu Bovis seu Bubali 50-100 weight portion
Rhizoma Smilacis Glabrae 30-150 weight portion Radix Et Rhizoma Rhei 6-20 weight portion Flos Sophorae Immaturus 15-60 weight portion
Radix Clerodenri Cyrtophylli 30-60 weight portion Radix Angelicae Sinensis 15-50 weight portion Radix Glycyrrhizae 6-15 weight portion
Caulis Spatholobi 30-60 weight portion.
2, pharmaceutical composition according to claim 1 is characterized in that said composition mainly made by following crude drug:
Process Zaocys 30 weight portion Scorpios 30 weight parts water Cornu Boviss seu Bubali 75 weight portions
The Rhizoma Smilacis Glabrae 90 weight portion Radix Et Rhizoma Rhei 13 weight portion Flos Sophorae Immaturus 40 weight portions
Radix Clerodenri Cyrtophylli 45 weight portion Radix Angelicae Sinensis 30 weight portion Radix Glycyrrhizaes 10 weight portions
Caulis Spatholobi 45 weight portions.
3, pharmaceutical composition according to claim 1 and 2 is characterized in that said composition adds acceptable accessories and makes acceptable forms clinically, as capsule, tablet, granule, oral liquid, drop pill, pill, powder, injection.
4, pharmaceutical composition according to claim 1 and 2 is characterized in that the preparation method of said composition is: will process Zaocys, Scorpio, Radix Et Rhizoma Rhei, the Flos Sophorae Immaturus, Radix Angelicae Sinensis, Radix Glycyrrhizae altogether powder become coarse powder standby; Again Rhizoma Smilacis Glabrae, Caulis Spatholobi, Cornu Bubali, Radix Clerodenri Cyrtophylli decocting are extracted 2-4 time, the taking liquid precipitation was collected clear liquor after 2-6 hour, was condensed into cream, add and to process Zaocys, Scorpio, Radix Et Rhizoma Rhei, the Flos Sophorae Immaturus, Radix Angelicae Sinensis, Radix Glycyrrhizae coarse powder and mix thoroughly, dry back powder is that fine powder is made capsule.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2004100391073A CN1289122C (en) | 2004-02-06 | 2004-02-06 | Medicinal composition for treating psoriasis and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2004100391073A CN1289122C (en) | 2004-02-06 | 2004-02-06 | Medicinal composition for treating psoriasis and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1557454A true CN1557454A (en) | 2004-12-29 |
| CN1289122C CN1289122C (en) | 2006-12-13 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB2004100391073A Expired - Fee Related CN1289122C (en) | 2004-02-06 | 2004-02-06 | Medicinal composition for treating psoriasis and preparation method thereof |
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| CN (1) | CN1289122C (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107095989A (en) * | 2017-05-31 | 2017-08-29 | 王滋东 | One kind treats psoriasic Chinese medicine and preparation method thereof |
-
2004
- 2004-02-06 CN CNB2004100391073A patent/CN1289122C/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107095989A (en) * | 2017-05-31 | 2017-08-29 | 王滋东 | One kind treats psoriasic Chinese medicine and preparation method thereof |
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| Publication number | Publication date |
|---|---|
| CN1289122C (en) | 2006-12-13 |
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