CN1539439A

CN1539439A - Medicine for intenerating blood vessel

Info

Publication number: CN1539439A
Application number: CNA031183026A
Authority: CN
Inventors: 黄益新
Original assignee: Individual
Current assignee: Individual
Priority date: 2003-04-22
Filing date: 2003-04-22
Publication date: 2004-10-27
Anticipated expiration: 2023-04-22
Also published as: CN1317011C

Abstract

A Chinese medicine in the form of decoction, incture, powder, capsule, or pill for softening blood vessel, coronary heart disease, cerebral arteriosclerosis and cerebral thrombosis is prepared from 5-10 Chinese-medicinal materials including haw, red sage root, fleece flower root, safflower, etc.

Description

A kind of arteriosclerosis medicine

Technical field

The present invention relates to a kind of arteriosclerosis medicine, belong to the Chinese medicine class.

Background technology

The means that the conventional at present treatment heart, cerebrovascular disease adopt are heart tonifying and blood vessel dilating, use the medicine symptomatic treatment.This Therapeutic Method pros and cons coherent of suiting the remedy to the case, and more harm than good.Sharp aspect be in time regulated the blood oxygen supply of heart, alleviated cardiopalmus, angina pectoris, weak clinical manifestation, removed patient's misery rapidly.1. the aspect of fraud shows uses the excited heart of cardiac tonic repeatedly, makes " energy " of cardiac muscle consume increasing, and the long-term passive over loading motion of heart will cause the further depletion of cardiac function; The expansion of blood vessel increases the attachment surface of blood vessel wall, further adheres to the condition created on the contrary metabolite on blood vessel wall.Here it is, and people often see, the heart patient must treat in secular medication repeatedly, and the reason place that dosage is also used bigger and bigger has to change other class cardiac tonic again behind the generation toxicity, from then on enters the process of vicious cycle.2. use the medicine of heart tonifying and blood vessel dilating for the first time, owing to make ischemia, anoxybiotic heart recover function very soon, cause the illusion of " medicine is good ", " sick " easily to patient, almost everybody has loosened the disposal to sclerosis, the narrow causes of disease such as vascular, benumbed people, once the disease recurrence, what at first expect is exactly that oneself cured " experience " of this disease in the past with others, further suit the remedy to the case again, caused the obstinate of disease.3. heart tonifying, diuresis and Pimobendane itself just have in various degree toxic and side effects and a dependency, As time goes on, patient is involuntary feel dose will be more with big more, the state of an illness is but more and more heavier, body constitution also worse and worse.Therefore, the heart, cerebrovascular disease should reach with vessel softening in treatment and regulate circulatory function, nourish heart that to protect the heart be that purpose " to because of " treats.

Technology contents

Purpose of the present invention: aim to provide a kind of arteriosclerosis medicine, use it can overcome tradition and suit the remedy to the case and cure the heart, the caused disadvantage of cerebrovascular disease medicine.

This arteriosclerosis medicine, it comprises: the combination of any 5-10 kind component in Fructus Crataegi 10-25 gram, Radix Salviae Miltiorrhizae 10-20 gram, Rhizoma Polygonati 10-20 gram, Radix Polygoni Multiflori 10-25 gram, Herba Artemisiae Scopariae 10-15 gram, Flos Chrysanthemi 10-15 gram, Semen Cassiae 10-15 gram, Squama Manis 5-10 gram, Herba Leonuri 10-20 gram, Flos Carthami 3-5 gram and the Radix Notoginseng 5-10 gram, above-mentioned component fried make tincture or pulverize, slightly carry capsule, ball all can.

The arteriosclerosis medicine that provides according to above technical scheme, its advantage is that prescription is simple, not simply to suit the remedy to the case to take stopgap measures and do not effect a permanent cure when using its treatment heart, cerebrovascular disease, can reach health invigorating, vessel softening, adjusting circulatory function, nourish heart and protect the purpose of the heart, finish " etiological treatment ".Through clinical observation on the therapeutic effect, wherein total effective rate reaches more than 92%.

The specific embodiment

Embodiment 1

Fructus Crataegi 15 restrains, Radix Salviae Miltiorrhizae 12 restrains, Rhizoma Polygonati 10 restrains, Semen Cassiae 15 restrains, Squama Manis 5 restrains, Herba Leonuri 12 restrains, Flos Carthami 3 restrains and Radix Notoginseng 10 restrains, and above-mentioned component is fried or make tincture or pulverizing, slightly carry honeyed pill all can.

Embodiment 2

Rhizoma Polygonati 15 restrains, Radix Polygoni Multiflori 15 restrains, Herba Artemisiae Scopariae 10 restrains, Flos Chrysanthemi 14 restrains, Semen Cassiae 11 restrains, Squama Manis 8 restrains, Herba Leonuri 19 restrains, Flos Carthami 4 restrains and Radix Notoginseng 7 restrains, and above-mentioned component is fried or make tincture or pulverizing, slightly carry honeyed pill all can.

Embodiment 3

Fructus Crataegi 10 restrains, Radix Salviae Miltiorrhizae 13 restrains, Rhizoma Polygonati 15 restrains, Radix Polygoni Multiflori 12 restrains, Herba Artemisiae Scopariae 13 restrains, Flos Chrysanthemi 10 restrains, Semen Cassiae 11 restrains, Squama Manis 6 restrains, Herba Leonuri 18 restrains, Flos Carthami 5 restrains and Radix Notoginseng 6 restrains, and above-mentioned component is fried or make tincture or pulverizing, slightly carry honeyed pill all can.

The function of this Chinese medicine mainly is a vessel softening, is used for the treatment of the heart, cerebrovascular disease.

Why the present invention adopts above prescription, mainly is based on following understanding:

The medicine of heart tonifying, diuresis and blood vessel dilating is ill-considered through the overall process of cardiovascular and cerebrovascular diseases, and be converted to " to Yin Shizhi " from " suiting the remedy to the case " is that main treatment comes up.The strict theory of treatment of diseases should be divided into " suiting the medicine to the illness " treatment in early stage, " to Yin Shizhi " and the three phases of last long keeping the treatment phase (to improve immunity and adaptive capacity) in mid-term.And people often look main treatment measure with " suiting the medicine to the illness " treatment of phase I, and the medicine of etiological treatment is in great shortage, and the critical phase III keeps treatment and almost nobody shows any interest in.It is not that simple " good medicine " with a kind of or a certain class just can solve for a kind of thorough solution of disease, and it is a complicated system engineering.Because the frightened disease of people, be eager to ask more ubiquity and " As the medicine took effect, the symptoms lessened " of psychology, " pain relieving rapidly ", the misleading and the analgesia of language such as " instant effect " advertisement of drugs, detumescence, analgesic, blood pressure lowering, though some produce effects of heart tonifying or the like are indulging in unbridled propaganda for of " controlling table does not effect a permanent cure " medicine soon but, misled patient, impelled medicine from research, evaluate clinical, application has to pay attention to " instant effect ", can remove disease rapidly, these phenomenons must be corrected, should follow and distinguish the cause of disease, draft the course of treatment---suit the medicine to the illness and dispose, palliate the agonizing sufferings---to because of the prescription, remove the cause of disease---restore funcitons, constitutional treatment route.

In the process of disease treatment, " suiting the remedy to the case " can only hold the patient and could adopt when can't stand big misery or threat to life, and necessary simultaneously attention is to the disposal of the cause of disease.In case clinical response (symptom) has obtained effective control, the sex pill of suiting the medicine to the illness must be stopped using or be reduced consumption gradually, therefore, the control clinical response (symptom) that the acute and chronic patient of morbidity just, light disease can not " suit the remedy to the case " at the very start is as long as " to Yin Shizhi " just can cure disease.Generally speaking, " symptomatic treatment " of critically ill patient based on Western medicine, and short-term adopts with analgesic, analgesia, excited or suppress the medicine etc. of neural, blood vessel dilating, adopts the antibiotic etiological treatment simultaneously.

Key is " to because of a prescription; remove the cause of disease ": the imbalance of the decline of immunity, the infection of pathogen, secretory function, the reduction of adaptive capacity is the basic reason that causes that disease takes place, red, swollen, clinical manifestation bitterly, the hypertension that patient presents, cough, expectorant, breathe heavily, gastrointestinal upset, clinical responses such as insomnia, cardiopalmus.Can not be considered as a kind of " bad phenomenon ", it is telling people in fact, and body has been subjected to the destruction of foeign element, the signal that the regulatory function of body self, adaptive capacity are degenerating.The immune system that body has been described is by " transfer ", at this time definitely directly the control of suiting the medicine to the illness property red, swollen, bitterly, hypertension, cough, expectorant, breathe heavily, gastrointestinal upset, the clinical response of insomnia, cardiopalmus etc.And should assist immune system go enantiopathy because of.Restore funcitons, health invigorating: cardiopathic treatment, according to the cause of disease, arteriosclerosis medicine, immunostimulant (adjusting) medicine are exactly first-selected, match restore funcitons as the case may be, and health invigorating is that main prescriptions of Chinese medicine is promptly accused and finished.Radix Salviae Miltiorrhizae, Fructus Crataegi, Radix Polygoni Multiflori, Rhizoma Polygonati, the Radix Astragali, not only vessel softening, enhancing immunity also have the effect that is made eye bright by blood, tonifying liver, but also heart tonifying, diuresis of the Radix Astragali.But Fructus Crataegi is resisting hypertension again: everything all utilizes cardiopathic rehabilitation.Cerebrovascular is an example, coronary heart disease, rheumatic heart disease, pericarditis, cerebral thrombosis, cerebral hemorrhage, cerebral arteriosclerosis etc., and controlling if distinguish disease is nothing but with vasodilation, heart tonifying, diuresis; Resisting hypertension, the medicine of antiinflammatory thrombolytic is in the hope of suiting the medicine to the illness.But vasodilation, heart tonifying, diuresis can not be used for cerebral hemorrhage: otherwise the blood vessel of hemorrhage is broken and threat to life more, and cerebral arteriosclerosis goes heart tonifying, diuresis to make an unnecessary move again.Thereby probing into of its heart, the cerebrovascular cause of disease still come from the sclerosis of blood vessel and narrow vascular after all, it is the difference at position, coronary heart disease is that sclerosis and narrow, the sclerosis of cerebral vessels and the narrow disease that just causes cerebral thrombosis, cerebral hemorrhage, cerebral arteriosclerosis have appearred in coronary artery.Cause sclerosis of blood vessels and narrow its further reason be virus, antibacterial infection, cause the deposition of metabolite on blood vessel wall, or the disorder of organism metabolism function, endocrine disturbance cause deposition of cholesterol and other foreign body or the like.Therefore, their " to because of " cures has not just had evident difference, in the treatment with vessel softening, nourish heart and protect the heart, antibacterial, antiviral, adjusting secretory function, remove metabolite, regulate " to because of " method of circulatory function, can be common to and treat all hearts, cerebrovascular disease.Patient's booster immunization old, weakness due to chronic disease is strengthened the deal of (adjusting) and hepatoprotective hematonic, and the healing of disease just has been not difficult.

Fructus Crataegi among the present invention: the expansion coronary vasodilator is arranged, increase coronary flow, reduce the effect of myocardial oxygen consumption and coefficient of oxygen utilization.Fructus Crataegi has hypotensive effect special of a specified duration.

Radix Salviae Miltiorrhizae: Radix Salviae Miltiorrhizae Injection has protective effect to the rat immunity hepatic fibrosis of albumin human's preparation, reduces the generation of circulating immune complex.Influence to non-specific immunity.TANSHINONES can obviously suppress to exempt from the circulating leukocyte lysosome and discharge, and engulf and adheres to, and it is moving significantly to suppress the leukocyte chemistry.

Rhizoma Polygonati: polygonatum polysaccharide has the moderate excitation to normal person's lymphocyte transformation, the patient's of immunologic hypofunction lymphocyte transformation is then had the excitation of height.Can improve the spleen hemolysis plaque and form cell number.Blood pressure lowering.The tool blood fat reducing, blood sugar lowering, arteriosclerosis, disease-resistant former, the sick effect of tuberculosis.

Radix Polygoni Multiflori: Radix Polygoni Multiflori can delay the degeneration and the atrophy of thymus, improves thymus microenvironment.Thymic weight and volume are obviously increased, and cortex significantly thickens, and the boundary of skin medullary substance is clear, and cell density obviously increases; The Radix Polygoni Multiflori and the Radix Astragali share, and can obviously promote the non-lymphocyte hypertrophy, help improving thymus microenvironment.In addition, also have hepatoprotective, function of gallbladder promoting, hypnosis, antioxidation, removing free radical, promote union of fracture, suppress fibroplasia, anticoagulant, resist myocardial ischemia, effect such as anti-ventricular fibrillation.

Herba Artemisiae Scopariae: to the effect of smooth muscle, antibiotic and anti-dermatophyte effect, skeletal muscle relaxation effect.

Flos Chrysanthemi: promote adrenal cortex function, promote phagocytosis, antibacterial action, the external human peripheral leucocytes that can improve is engulfed golden yellow.Refrigeration function, antiinflammatory action its role is to promote the synthetic of antepituitary ACTH and has secreted the enhancing human body immunity function.

Squama Manis: immunoregulation effect alleviates immuning tissue's ischemic lesions nervous system dysfunction.Anti-allergic effects.

Herba Leonuri: the propagation that promotes thymocyte cell (T lymphocyte).Promote the phagocytic function of macrophage, antiallergic action, resisting transplant rejection reaction.Herba Leonuri all has inhibitory action to thrombotic each stage, platelet aggregation, platelet thrombus formation, fibrinous thrombus formation and erythrocyte aggregation etc. are all had obviously to be alleviated, family is exempted from thrombosis have dissolution, these effects are favourable to the performance of immunologic function.The Herba Leonuri mixture of being made up of Herba Leonuri and Fructus Crataegi has obvious inhibition histamine metabolism, can obviously reduce histamine content in arteriosclerosis animal pattern (chicken) blood plasma, the heart and the cerebral tissue.

Flos Carthami: have blood pressure lowering, blood vessel dilating, antithrombotic to form, improve mice hypoxia-bearing capability, analgesia, press down effects such as tumor, blood fat reducing, leukemia, ischemic myocardium thromboembolism and ischemia retina injury are all had protective effect.

Radix Notoginseng: antiinflammatory action, strengthen hypophysis--adrenal cortex function, strengthen hemopoietic function of bone marrow and function of increasing leukocyte, the bone marrow pluripotent stem cell there be hypertrophy, differentiation and the migration of promotion.Strengthen the mononuclear phagocyte system function, promote the immune organ hypertrophy, can obviously increase the weight of spleen and thymus, and can make the spleen of caused by cyclophosphamide and thymic weight decline that tangible rise is arranged.Arasaponin can reduce the body allergy and advance too high cellular immune function, and the mice delayed hypersensitivity is had significant inhibitory effect; Radix Notoginseng also can make the low antigenic information function of accepting in the impaired back of lymphocyte bring up to normal level.Can resist by the cellular immune function of caused by cyclophosphamide low.Arasaponin can pass through to increase the kill capability of activated immunocyte, thereby improves the anti-tumor activity of body.Strengthen humoral immune function, Radix Notoginseng can significantly improve impaired lymphocyte antibody and produce ability.The Radix Notoginseng decoct can significantly improve the spleen hemolysis plaque and form cell quantity.Promptly improve red blood cell adhesion immune complex ability and erythrocyte C3B receptor active, help removing immune complex, keeping the immune Stabilization of body, and this effect has dose dependent.But Radix Notoginseng anticoagulant, blood viscosity lowering, expansion peripheral blood vessel, reduction arteriotony reduce cardiac load, reduce myocardial oxygen consumption, and effects such as blood pressure lowering, arrhythmia are arranged.

The present invention adapts to disease: all hearts, cerebrovascular disease.As coronary heart disease, cerebral arteriosclerosis, cerebral thrombosis or the like.

Case 1: poplar * *, 46 years old, the women, rheumatic heart disease is lived the changde, hunan province city, and clothes arteriosclerosis medicine 6 years is almost recovered.

Case 2: relax * *, the women, the positive people of Hunan fiber crops suffered from scleroderma 3 years, once spent more than 20,000 yuan invalid, the softening medicine of intravascular is cured and was clearly better in 1 year.

Case 3: once * *, the positive people of women Hunan fiber crops spends more than 10,000 yuan half a year and still is unable to leave the bed, and the softening medicine of intravascular is cured and was significantly taken a turn for the better in 1 year.

Claims

1, a kind of arteriosclerosis medicine, it is characterized in that it comprises the combination of any 5-10 kind component in Fructus Crataegi 10-25 gram, Radix Salviae Miltiorrhizae 10-20 gram, Rhizoma Polygonati 10-20 gram, Radix Polygoni Multiflori 10-25 gram, Herba Artemisiae Scopariae 10-15 gram, Flos Chrysanthemi 10-15 gram, Semen Cassiae 10-15 gram, Squama Manis 5-10 gram, Herba Leonuri 10-20 gram, Flos Carthami 3-5 gram and the Radix Notoginseng 5-10 gram, above-mentioned component fried make tincture or pulverize, slightly carry capsule, ball all can.