CN101396543A - Pure traditional Chinese medicine preparation for treating cardio-cerebrovascular disease - Google Patents

Abstract

A pure traditional Chinese medicine preparation for treating cardiovascular diseases is characterized in that the pure traditional Chinese medicine preparation is prepared by traditional Chinese medicine raw materials with the following parts by weight: 5-10 parts of safflower, 10-20 parts of motherwort herb, 4-8 parts of danshen root, 4-8 parts of Szechuan lovage rhizome, 2-4 parts of medicinal cyathula root, 3-6 parts of peach seed, 2-4 parts of trogopterus dung, 2-4 parts of common burreed rhizome, 2-4 parts of zedoary, 2-4 parts of turmeric, 1-2 parts of dragon blood, 3-6 parts of clematis root, 2-4 parts of gentiana macrophylla, 2-4 parts of heracleum hemsleyanum michaux, 2-4 parts of radix stephaniae tetrandrael, 2-4 parts of sea-ear shell, 2-4 parts of oyster shell, 2-4 parts of puncturevine caltrop fruit, 3-6 parts of uncaria, 1-2 parts of stiff silkworm, 0.2-0.4 part of scorpion, 4-8 parts of rhubarb, 2-4 parts of ephedra herb, 2-4 parts of pepperweed seed, 2-4 parts of bitter apricot seed, 2-4 parts of sessile stemona root, 4-8 parts of unibract fritillary bulb, 2-4 parts of snakegourd fruit, 2-4 parts of arisaema cum bile, 2-4 parts of pinellia tuber, 2-4 parts of nutgrass galingale rhizome, 2-4 parts of rhizoma corydalis, 2-4 parts of Chinese eaglewood, 2-4 parts of cassia seed, 2-4 parts of common selfheal fruit-spike, 1-2 parts of cicada slough, 3-6 parts of honeysuckle flower, 2-4 parts of chrysanthemum, 3-6 parts of baical skullcap root, 2-4 parts of golden thread, 2-4 parts of tree peony bark, 4-8 parts of red paeony root, 4-8 parts of tuber fleeceflower root and 4-8 parts of membranous milk vetch root. The pure traditional Chinese medicine preparation is used for treating various cardiovascular diseases, the sequelae and the complications thereof.

Description

The pure Chinese medicinal preparation of treatment cardiovascular system diseases

Technical field

The present invention is the pure Chinese medicinal preparation of treatment cardiovascular system diseases, and belonging to the Chinese herbal medicine is the human drugs of raw material.

Background technology

Cardiovascular disease comprises heart disease, hypertension, hyperlipemia etc.Characteristics with " sickness rate height, mortality rate height, disability rate height, relapse rate height " and " complication is many ".Its cause of disease mainly is an arteriosclerosis.Arteriosclerosis is that the arteries inwall has depositions such as fat, cholesterol, and is accompanied by pathological changes such as the formation of fibrous tissue and calcification.This pathological development then forms coronary heart disease (heart and brain pain, myocardial infarction and acute death) during to heart coronary artery.From normal tremulous pulse to asymptomatic atherosclerosis, the arterial pulse pipe is narrow, needs surplus in the of ten year the time to decades.But to Symptomatic arteriosclerosis,, only need a few minutes as coronary heart disease or apoplexy from asymptomatic arteriosclerosis.A lot of patients do not have preventive measure, so mortality rate is very high because of having no mental preparation yet.

Now the whole world has nearly 1/4th populations to be threatened by cardiovascular and relevant disease, and throughout one's life, the life that has 1/3rd people is shrouded by the cardiovascular disease shade, has 1/5th population to die from cardiovascular related diseases at last.Therefore, with the fight of cardiovascular disease not subregion, ethnic group, become one of challenge of the whole mankind.According to World Health Organization's prediction, to the year two thousand twenty, noninfectious will account for 79% of China's cause of death, and wherein cardiovascular disease accounts for the first place.

Sickness rate in recent years has the trend that increases year by year according to investigations, and in, young patient constantly increases, cardiovascular system diseases has become commonly encountered diseases, the frequently-occurring disease of harm China people ' s health. and why can cardiovascular system diseases become first killer in all diseases? except not obvious, the sudden reasons such as many of sensory symptoms, most important reason is: up till now, 1. do not have method and the medicine that can treat; 2. though can treat, can only alleviate or delay disease progression, can not effect a radical cure and reach the standard of recovery from illness! 3. because preceding 2 or other reasons make the patient enter critical days or later stage, sudden onset or increase the weight of gradually often adds the complication of appearance and dead or produce the sequela that is difficult to cure. finally have only maimed person or death! Also there is not a cover can thoroughly cure the effective therapy and the medicine of various cardiovascular system diseases in a word by now.

Summary of the invention

The object of the present invention is to provide a kind of pure Chinese medicinal preparation for the treatment of cardiovascular system diseases.

Specifically, a kind of pure Chinese medicinal preparation for the treatment of cardiovascular system diseases is characterized in that making with the raw material of Chinese medicine that contains following weight parts:

By Flos Carthami 5-10, Herba Leonuri 10-20, Radix Salviae Miltiorrhizae 4-8, Rhizoma Chuanxiong 4-8, river cattle sunset 2-4, Semen Persicae 3-6, Oletum Trogopterori 2-4, rhizoma sparganic 2-4, Rhizoma Curcumae 2-4, Rhizoma Curcumae Longae 2-4, Sanguis Draxonis 1-2, Radix Clematidis 3-6, Radix Gentianae Macrophyllae 2-4, Radix Angelicae Pubescentis 2-4, Radix Stephaniae Tetrandrae 2-4, Concha Haliotidis 2-4, Concha Ostreae 2-4, Fructus Tribuli 2-4, Ramulus Uncariae Cum Uncis 3-6, Bombyx Batryticatus 1-2, Scorpio 0.2-0.4, Radix Et Rhizoma Rhei 4-8, Herba Ephedrae 2-4, Semen Lepidii (Semen Descurainiae) 2-4, Semen Armeniacae Amarum 2-4, Radix Stemonae 2-4, Bulbus Fritillariae Cirrhosae 4-8, Fructus Trichosanthis 2-4, Arisaema Cum Bile 2-4, Rhizoma Pinelliae 2-4, Rhizoma Cyperi 2-4, Rhizoma Corydalis 2-4, Lignum Aquilariae Resinatum 2-4, Semen Cassiae 2-4, ancient careless 2-4 of summer, Periostracum Cicadae 1-2, Flos Lonicerae 3-6, Flos Chrysanthemi 2-4, Radix Scutellariae 3-6, Rhizoma Coptidis 2-4, Cortex Moutan 2-4, Radix Paeoniae Rubra 4-8, Radix Polygoni Multiflori 4-8, Radix Astragali 4-8.

Increase Ganoderma, Semen Ziziphi Spinosae, Caulis Polygoni Multiflori, Herba Apocyni veneti, Pheretima, Fructus Perillae, Radix Gentianae, Cortex Phellodendri, chitin in the above-mentioned prescription of the present invention to increase therapeutic domain, the prescription of formation is:

Flos Carthami 5-10, Herba Leonuri 4-8, Radix Salviae Miltiorrhizae 4-8, Rhizoma Chuanxiong 4-8, river cattle sunset 2-4, Semen Persicae 3-6, Oletum Trogopterori 2-4, rhizoma sparganic 2-4, Rhizoma Curcumae 2-4, Rhizoma Curcumae Longae 2-4, Sanguis Draxonis 1-2, Radix Clematidis 3-6, Radix Gentianae Macrophyllae 2-4, Radix Angelicae Pubescentis 2-4, Radix Stephaniae Tetrandrae 2-4, Ganoderma 3-6, Semen Ziziphi Spinosae 3-6, Caulis Polygoni Multiflori 2-4, Concha Haliotidis 2-4, Concha Ostreae 2-4, Herba Apocyni veneti 1-2, Fructus Tribuli 2-4, Pheretima 2-4, Ramulus Uncariae Cum Uncis 3-6, Bombyx Batryticatus 1-2, Scorpio 0.2-0.4, Radix Et Rhizoma Rhei 4-8, Herba Ephedrae 2-4, Fructus Perillae 2-4, Semen Lepidii (Semen Descurainiae) 2-4, Semen Armeniacae Amarum 2-4, Radix Stemonae 2-4, Bulbus Fritillariae Cirrhosae 4-8, Fructus Trichosanthis 2-4, Arisaema Cum Bile 2-4, Rhizoma Pinelliae 2-4, Rhizoma Cyperi 2-4, Rhizoma Corydalis 2-4, Lignum Aquilariae Resinatum 2-4, Semen Cassiae 2-4, ancient careless 3-6 of summer, Periostracum Cicadae 1-3, Flos Lonicerae 3-6, Flos Chrysanthemi 2-4, Radix Scutellariae 3-6, Rhizoma Coptidis 2-4, Radix Gentianae 2-4, Cortex Phellodendri 2-4, Cortex Moutan 2-4, Radix Paeoniae Rubra 4-8, Radix Polygoni Multiflori 4-8, Radix Astragali 4-8, chitin 0.5-1.

Fructus Crotonis among the present invention, Radix Notoginseng, Flos Carthami, Radix Polygoni Multiflori, the black and white Semen Pharbitidis, Herba Leonuri, the Radix Astragali, Niu Xi, Radix Clematidis, the Rhizoma Pinelliae, XUELINGZHI, medical herbs such as Rhizoma Arisaematis and field dobber. (take down crust with Fructus Crotonis, the heart and inner membrance, and parching to brown) be principal agent compatibility Rhizoma Pinelliae Preparata, GUANG Radix Notoginseng, Arisaema Cum Bile, Calculus Bovis, Cortex Moutan, Flos Carthami, Sanguis Draxonis, LIGNUM AQUILARIAE SINENSIS from Hainan of China, Rhizoma Cyperi, medicine such as Bombyx Batryticatus and Periostracum Cicadae has been formulated out and can have been controlled infectious disease (angry film inflammation, pestilence, cholera, pneumonia, pulmonary abscess, pulmonary tuberculosis), cardiovascular system diseases (hypertension, heart disease, arteriosclerosis) ， Epilepsy Epilepsy, psychosis (various types of psychosiss, schizophrenia particularly), Mai Niersi syndrome, gastroenteropathy (intestinal obstruction, constipation. dyspepsia, food stagnation), rheumatism (whole body, the joint, rheumatic heart disease), various inflammation are as toothache. oculopathy (glaucoma, pink eye disease), the various diseases of children's are as infantile convulsion etc., intractable headache, migraine, hepatopathy; Be that medicines such as main compatibility Rhizoma Acori Graminei, Radix Rehmanniae Preparata, field dobber have been formulated out big also pellet with Radix Polygoni Multiflori again, for treating various deficient syndromes, cardiovascular system diseases. anemia, the tonification good medicine of many difficult miscellaneous diseases such as gynaecological disease; Be the relevant medicine of principal agent compatibility Rhizoma Cyperi with the black and white Semen Pharbitidis again, compatibility Calculus Bovis, Arisaema Cum Bile, Cordyceps, Flos Carthami, Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong etc. have been succeeded in developing multiple diseases such as can saving critically ill patient's life, healing cardiovascular system.Simultaneously, be that principal agent compatibility Herba Leonuri, Radix Polygoni Multiflori, the Radix Astragali, Radix Salviae Miltiorrhizae, Radix Paeoniae Rubra, Rhizoma Chuanxiong, Radix Et Rhizoma Rhei etc. have been succeeded in developing and can have been healed the wounded and rescue the dying with Flos Carthami (have another name called red blue flower), can thoroughly cure the Chinese medicine preparation of the present invention of multiple disease such as cardiovascular system.

Principal agent wherein: Flos Carthami-red blue flower. one. our a century (1902-2008) comes a large amount of medical practices and very high curative effect and cure rate to prove: before the seventies, modern medicine and Chinese herbology are thought: the Chinese herbal medicine Flos Carthami can only be treated gynaecological disease; Invigorate blood circulation moisturize, pain-relieving powder for treating swells, stimulate the menstrual flow, diseases due to noxious agents produced by various parasites; Few with nourishing blood; Ampoule surpasses 10 grams can removing blood stasis.But the inventor finds excess and uses Flos Carthami and treat cardiovascular disease! The current new property of medicine and the function of finding Flos Carthami: (1) can improve hemodynamics, decreased heart rate, increase pipe arteries and veins flow, improves cardiac function, regulates myocardial metabolism, reduces myocardial oxygen consumption, reaches the expansion peripheral blood vessel, increases organic blood flow volume, reduces vascular resistance, improve each histoorgan microcirculation; (2) can obviously suppress functions such as the adhesion of little blood plate, gathering and release, the energy prolongation is hemorrhage, blood coagulation blood plasma is answered calcium and prothrombin time, significant anticoagulation is arranged, can suppress thrombosis, the blood fibrinolytic system is had obvious potentiation, the newborn thrombosis of solubilized, anti-tampon further develops, the energy blood viscosity lowering improves hemorheological property, and blood fat reducing and prevention of arterial are atherosis; (3) have antiinflammatory, analgesia, adjusting immunologic function; (4) have resist myocardial ischemia, anti-arrhythmia and anti-hepatic fibrosis.

Have a talk ministerial drug Radix Et Rhizoma Rhei among the present invention now again.Radix Et Rhizoma Rhei is the cathartic drug in the purgatives medicine, has done following argumentation about Radix Et Rhizoma Rhei in the pharmacopeia: " function " (1) heat and toxic materials clearing away, with controlling stagnant constipation; (2) clearing away heat-fire, scorching with controlling on the pathogenic fire, headache conjunctival congestion, pharyngalgia, Chi Gingival swell and ache, aphtha of the mouth and tongue, and damp and hot jaundice, stranguria; (3) pathogenic fire purging hemostasis, heat in blood is spitted blood with controlling, epistaxis; (4) heat-clearing and toxic substances removing is with controlling pathopyretic ulcer, burn and scald; (5) blood circulation promoting and blood stasis dispelling is with controlling amenorrhea due to the blood stasis, lochiostasis, lump in the abdomen and traumatic injury. " pharmacological action " catharsis, function of gallbladder promoting, protect the liver. suppress pancreatin, antiulcer, broad-spectrum antiseptic, antifungal, antiviral, protozoacide, analgesic, antiinflammatory, antitumor, hemostasis, blood fat reducing. blood viscosity lowering, reduce blood urea nitrogen, improve renal function, diuresis, heart tonifying, antioxidation." modern Application " hemoptysis of pulmonary tuberculosis, tuberculous lymphadenitis, pneumonia, epidemic hemorrhagic fever, hyperlipidemia, renal failure, acute enteritis, bacillary dysentery, viral hepatitis, ulcer perforation, upper gastrointestinal hemorrhage, acute cholecystitis, cholelithiasis, biliary colic, acute pancreatitis, acute appendicitis, intestinal obstruction, prostatitis, acute urinary retention, vaginitis, cervical erosion, pelvic inflammatory disease. traumatic hemorrhage, cold injury, burn. the memory lumbar sprain. acute tonsillitis, recurrent aphtha, epistaxis, psoriasis, the fat descendants dermatitis that overflows, rosacea, the cutization pyogenic infection. this shows that Radix Et Rhizoma Rhei is a kind of Chinese herbal medicine that can treat the very important of multiple disease and have long-range future! Therefore be used for the treatment of multiple diseases such as psychosis and cardiovascular system in the present invention.The inventor finds the hypotensive effect of Radix Et Rhizoma Rhei far above any depressor in the Chinese medicine, particularly with relevant Chinese herbal medicine compatibility. more important role is that the hypertensive complication of treatment and other multiple sick effect are outstanding! Cathartic drug-Radix Et Rhizoma Rhei that past is looked down upon by the general traditional Chinese medical science, past and our medical practice explanation nowadays, it is to treat cardiovascular disease especially to bringing high blood pressure down, and thoroughly cures other multiple disease such as hypertension and complication and psychosis etc. and has made distinctions won on the battlefield!

(chitin claims chitin or chitosan again to new drug chitin among adding the present invention.Chitin has five functional through experimental medicine proof: 1. activating human body cells slows down aging .2. liver detoxification and strengthens biotransformation function .3. and coordinate human body organ function .4. and promote body to discharge self to produce or enter intravital harmful substance .5. reinforced immunological to increase self-healing ability. and chitin is in good health and a long life, application on the cerebrovascular sclerosis disease, application in the diabetes control, with prevention and control of cancer, hypertensive treatment, the gastroduodenal ulcer treatment, hepatic insufficiency treatment and the aspect such as in the traumatology department, use important effect is all arranged.

Ministerial drug 52 is distinguished the flavor of totally among the present invention, and it is by one. blood circulation promoting medicine: Herba Leonuri, Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong, Niu Xi, Semen Persicae, Oletum Trogopterori, rhizoma sparganic, Rhizoma Curcumae, Rhizoma Curcumae Longae, Sanguis Draxonis; Two. the pungent and warm medicine for relieving the exterior syndrome in the diaphoretic medicine: Herba Ephedrae; Pungent and cold medicine for relieving the exterior syndrome: Flos Chrysanthemi Periostracum Cicadae; Three. sedative: Semen Ziziphi Spinosae, Caulis Polygoni Multiflori, Ganoderma; Four. the analgesic blood-cooling drugs in the antipyretic: Cortex Moutan, Radix Paeoniae Rubra; Heat clearing and dampness removing medicine: Radix Scutellariae, Rhizoma Coptidis, Radix Gentianae, Cortex Phellodendri; Clearing away heat to improve acuity of vision medicine: Semen Cassiae, Spica Prunellae; Heat and toxic materials clearing away medicine: Flos Lonicerae; Five. the Qi-tonifying drug in the tonic: the Radix Astragali; Hematonic: Radix Polygoni Multiflori; Six. QI regulating medicine: Rhizoma Cyperi, Rhizoma Corydalis; Seven. the cathartic drug in the purgatives medicine: Radix Et Rhizoma Rhei; Eight. the medicine for calming liver and calming endopathic wind in the liver-pacifying medicinal: Pheretima, Ramulus Uncariae Cum Uncis, Bombyx Batryticatus, Scorpio; The suppressing the hyperactive liver and subsiding YANG medicine:, Concha Haliotidis, Concha Ostreae, Herba Apocyni veneti, Fructus Tribuli; Nine. the wind-damp dispelling stopping numbness pain medicine in the medicine for rheumatism: Radix Clematidis, Radix Gentianae Macrophyllae, Radix Angelicae Pubescentis, Radix Stephaniae Tetrandrae; The wide expectorant medicine of warm heat transforming into cold in the ten expectorant cough suppressant and anti-asthmatic sesame medicines: the Rhizoma Pinelliae; Qinghua heat-phlegm medicine: Bulbus Fritillariae Cirrhosae, Fructus Trichosanthis, Arisaema Cum Bile; Medicine for the treatment of cough and asthma: Fructus Perillae, Semen Lepidii (Semen Descurainiae), Semen Armeniacae Amarum, the Radix Stemonae.; 11. chitin.Totally ten one classes are formed. and hence one can see that: 1. function, pharmacological action and the range of application of monarch drug will be strengthened and promote to their adding greatly; 2. can find out by the title and the function of their classification: (1). our compatibility is numerous and very reasonable. and our ministerial drug reaches 52 flavors. because the cardiovascular disease kind is many, the disease of initiation is wide, and complication is quite a lot of, so used above mention one, to 11 class medicines. for treatment with thoroughly cure modern medicine and the Chinese herbology difficulty is big and the cardiovascular system diseases of weak curative effect, be to have made the most appropriate arrangement and strong material guarantee is provided, thus, using so, numerous ministerial drugs is very rational; (2). very comprehensive; because cardiovascular system is most important and be difficult to substitute or compensation for other organ or system in the human body; according to human body is the viewpoint of the same entity of an opposition; it is in a single day ill; to have influence on other each organ and system is undesired or the morbidity; produce many complication simultaneously; there is not numerous medicines; appropriate compatibility, the disease that painstaking effort are closed system is to treat, let alone the problem .3. boiling extraction of how thoroughly to cure; highly concentrate and state as mentioned, for treatment and the thorough cardiovascular system diseases of curing have been laid solid material base!

The present invention adopts boiling extraction, and is highly concentrated, and the advantage with traditional Chinese medical science decoction treatment disease has performed to the limit, plays or reaches former Chinese medicine decoction be beyond one's reach purpose and effect!

The main effect of the effect of medicine of the present invention is summarized as with ballad:

The Flos Carthami YAOJING is very marvellous, cures painstaking effort and is heroes!

Century-old practice is created miracles, and the innovation and creation medical skill is pretty.

Numerous full Gus of compatibility, various diseases could be cured!

Concentrated medicament way height, the extremely strong disease of curative effect disappears entirely!

Blood pressure blood fat viscosity is different, mixes up very marvellous rapidly.

The vessel softening siddhi is proud, cures painstaking effort and belongs to top news.

Can cure all kinds of diseases and ailments complication, the painstaking effort recovery from illness is two.

Must cooperate and also give birth to pellet, each shows very can the curative effect height.

Century-old effect is a witness, and it is good to put into practice first medicine!

1, the adding of a large amount of ministerial drugs is strengthened widely and has been promoted the curative effect that the monarch drug Flos Carthami is cured the disease.

2, compatibility is numerous, reaches 53 flavors, looks after comprehensively, cures all kinds of diseases and ailments;

" Flos Carthami essence-1 " formed and to be reached 53 flavors, and it is made of blood circulation promoting medicine, medicine for rheumatism, liver-pacifying medicinal, purgatives medicine, QI regulating medicine, expectorants, antitussives and anti-asthmatics medicine, antipyretic, sedative, tonic, diaphoretic medicine and chitin 11 class medicines. and this is because of the complexity of cardiovascular disease and other difficult miscellaneous diseases, intractable and curative effect is extremely undesirable determines! It has not only played conclusive effect (is the viewpoint of a unity of opposites body according to human body) to the treatment cardiovascular system diseases but also can treat because of other organ of the ill initiation of painstaking effort official system and disease, complication and other multiple disease of system, as: rheumatism, emphysema, gynaecological disease, psychosis, gastrointestinal disease, infectious disease and tumor an or the like disease! . a century facts have proved the power and the pharmacological action of " red words smart-1 " treatment diseases!

3. employing boiling extraction, again the ratio of medicinal liquid (traditional Chinese medical science decoction) in 1/20 concentrated (medicinal liquid that is about to 20 liters is concentrated to 1 liter), so the advantage of just traditional Chinese medical science decoction being cured the disease has performed to the limit, of paramount importancely is: 1. still be decoction, be convenient to absorption of human body; 2. the curative effect of medicine is not 20 times of mathematical calculation, facts have proved big Radix Achyranthis Bidentatae! 3. play and solved general Chinese medicine: the A. medicine is wanted the focus that reaches and the purpose B. cardiovascular system diseases that is beyond one's reach is difficult to cure the problem that maybe can't cure.

4. its major function: 1. can save critically ill patient's life, thoroughly cure cardiovascular system diseases; 2. can the increase sharply amount of blood supply of each organ and tissue, the oxygen content 3. that improves in the blood can make hyperpietic's blood pressure reduce, and also can make hypotensive's hypertension; 4. the blood circulation promoting and blood stasis dispelling fat bolt vessel softening treatment arteriosclerosis that disappears; 5. training the mind Trane 6. antiphlogistic and bactericidals of refreshing oneself of having one's ideas straightened out; 7. the scorching anti-tumor eliminating carbuncle of calm eliminating toxic substances to remove stasis blood fat-reducing blood pressure-decreasing anticoagulant blood sugar lowering viscosity reduction that reduces phlegm; 8. activating human body slows down aging life lengthening rejuvenation; 9. liver detoxification strengthens biotransformation orthofunction organ dysfunction promotion body discharge self generation or enters nuisance in the body; 10. raising autoimmunity, reinforced immunological increases self-healing ability.

5, cure mainly: angina pectoris, acute cardiac muscle bosom is dead, dyslipidemia and atherosclerosis, hypertension and complication, coronary heart disease, rheumatic heart disease, pulmonary heart disease, cerebral thrombosis, cerebral hemorrhage, coronary atherosclerosis, hyperlipidemia, rheumatism, bronchial asthma, emphysema, various gastroenteropathy, various hemorrhage, spitting of blood and epistaxis, various gynaecological diseases, hepatitis, prostatic hyperplasia, migraine, alzheimer disease, but life lengthening, in the raising, youth and teenager and child's intelligence, give anti-alzheimer disease.

6, the scope of application: various cardiovascular system diseases and sequela thereof and complication.

7, property of medicine reaction: take this medicine and must do by doctor's requirement, can not be excessive! If an amount of or all have no side effect in a small amount and bad reflection, but a large amount of or excess is easy to mouthful, nose or other organ hemorrhage, and the anemia of pregnant woman definitely can not take.

8, dosage: obey the 10-20 milliliter the general every day of being grown up. the patient of cardiovascular disease, can obey 20 milliliters every day, if twice/day. each 10 milliliters sooner or later, if three times/day, early, middle and late each 7-6-7 milliliter. the patient of other disease, generally, twice/day, each 5 milliliters sooner or later. suitably dosage is being in a bad way; The child can reduce to the 1/4-2/3. of adult's amount according to the age size

9, instructions of taking: eliminating cold for resuscitation water clothes are down.

10, taboo: anemia of pregnant woman

11, explanation: except that the anemia of pregnant woman can not take, generally by doctor's advice or an amount of short-term or take for a long time and all do not find side effect and quantitative response not.

The specific embodiment

A kind of pure Chinese medicinal preparation for the treatment of cardiovascular system diseases, its be with the raw material of Chinese medicine of following weight parts make (unit: kilogram, down with):

Flos Carthami 5-10, Herba Leonuri 10-20, Radix Salviae Miltiorrhizae 4-8, Rhizoma Chuanxiong 4-8, river cattle sunset 2-4, Semen Persicae 3-6, Oletum Trogopterori 2-4, rhizoma sparganic 2-4, Rhizoma Curcumae 2-4, Rhizoma Curcumae Longae 2-4, Sanguis Draxonis 1-2, Radix Clematidis 3-6, Radix Gentianae Macrophyllae 2-4, Radix Angelicae Pubescentis 2-4, Radix Stephaniae Tetrandrae 2-4, Concha Haliotidis 2-4, Concha Ostreae 2-4, Fructus Tribuli 2-4, Ramulus Uncariae Cum Uncis 3-6, Bombyx Batryticatus 1-2, Scorpio 0.2-0.4, Radix Et Rhizoma Rhei 4-8, Herba Ephedrae 2-4, Semen Lepidii (Semen Descurainiae) 2-4, Semen Armeniacae Amarum 2-4, Radix Stemonae 2-4, Bulbus Fritillariae Cirrhosae 4-8, Fructus Trichosanthis 2-4, Arisaema Cum Bile 2-4, Rhizoma Pinelliae 2-4, Rhizoma Cyperi 2-4, Rhizoma Corydalis 2-4, Lignum Aquilariae Resinatum 2-4, Semen Cassiae 2-4, ancient careless 2-4 of summer, Periostracum Cicadae 1-2, Flos Lonicerae 3-6, Flos Chrysanthemi 2-4, Radix Scutellariae 3-6, Rhizoma Coptidis 2-4, Cortex Moutan 2-4, Radix Paeoniae Rubra 4-8, Radix Polygoni Multiflori 4-8, Radix Astragali 4-8

The present invention's prescription also can be adjusted into: Flos Carthami 5-10, Herba Leonuri 4-8, Radix Salviae Miltiorrhizae 4-8, Rhizoma Chuanxiong 4-8, river cattle sunset 2-4, Semen Persicae 3-6, Oletum Trogopterori 2-4, rhizoma sparganic 2-4, Rhizoma Curcumae 2-4, Rhizoma Curcumae Longae 2-4, Sanguis Draxonis 1-2, Radix Clematidis 3-6, Radix Gentianae Macrophyllae 2-4, Radix Angelicae Pubescentis 2-4, Radix Stephaniae Tetrandrae 2-4, Ganoderma 3-6, Semen Ziziphi Spinosae 3-6, Caulis Polygoni Multiflori 2-4, Concha Haliotidis 2-4, Concha Ostreae 2-4, Herba Apocyni veneti 1-2, Fructus Tribuli 2-4, Pheretima 2-4, Ramulus Uncariae Cum Uncis 3-6, Bombyx Batryticatus 1-2, Scorpio 0.2-0.4, Radix Et Rhizoma Rhei 4-8, Herba Ephedrae 2-4, Fructus Perillae 2-4, Semen Lepidii (Semen Descurainiae) 2-4, Semen Armeniacae Amarum 2-4, Radix Stemonae 2-4, Bulbus Fritillariae Cirrhosae 4-8, Fructus Trichosanthis 2-4, Arisaema Cum Bile 2-4, Rhizoma Pinelliae 2-4, Rhizoma Cyperi 2-4, Rhizoma Corydalis 2-4, Lignum Aquilariae Resinatum 2-4, Semen Cassiae 2-4, ancient careless 3-6 of summer, Periostracum Cicadae 1-3, Flos Lonicerae 3-6, Flos Chrysanthemi 2-4, Radix Scutellariae 3-6, Rhizoma Coptidis 2-4, Radix Gentianae 2-4, Cortex Phellodendri 2-4, Cortex Moutan 2-4, Radix Paeoniae Rubra 4-8, Radix Polygoni Multiflori 4-8, Radix Astragali 4-8, chitin 0.5-1.

Preparation method: one. at first dry or dry (heavy 127.2-249.4) and be crushed to 60-100 order (being more conducive to leach active ingredient) by 52 flavors of forming (chitin does not temporarily add, and adds at last) medicine; Two. then will pulverize medicated powder and press: medicated powder is heavy: the amount of water weight=1:5-6, with the active ingredient in the boiling water leaching medicated powder; 1. adding in the heater (big iron pan or reactor) than the heavy 5-6 of medicated powder water doubly; 2. under condition of stirring, medicated powder all added in the entry 3. and be heated to boiling under stirring; 4. under agitation heated 2 hours, under the ebullient situation of 100 degree, leach medicinal liquid for the first time with boiling water, because not sealing, opens wide by heater, after the water boiling, As time goes on will constantly evaporate, and must constantly add entry, keep the height of original liquid level, to obtain the medicinal liquid of a certain amount of leaching, and when leaching for the first time, medicated powder will be drawn a large amount of moisture (be about own wt 2-3 times), 5. after heating has been leached, liquid-solid body must be separated, take artificial isolated by filtration or dry separation all can with centrifuge. medicinal residues are collected and are done to leach usefulness for the second time, and liquid medicine collecting is standby; Three. second and the 3rd batch with boiling water leaching, and water consumption, heat time heating time and other method are fully with two. and identical, can obtain two or three batches of leaching liquids. four. non-airtight the concentrated of medicinal liquid of leaching down: 1. with one, two and three batch of leachate mix homogeneously; 2. then pour in the former heater of wash clean leaching medicinal liquid; 3. boiled, under the boiling situation, concentrate; 4. so As time goes on medicinal liquid constantly reduces and concentration improves constantly. when the medicinal liquid liquid level is reduced to original 2/3 or 1/2 the time, the medicinal liquid that will add unconcentrated leaching, the height .5. that reaches former liquid level will leach medicinal liquid at last and be concentrated to 1/20 of original volume or weight, add the 0.5-1 chitin at last. stir, just made " Flos Carthami essence-1 " oral liquid that meets the requirements. in order to prolong storage life. generally under heating, add 10% white sugar again. being used for diabetics more and being not suitable for taking the crowd who contains sugared medicine of not sugaring

Experience (all by manual operations) according to our pharmacy: during boiling extraction, if amount of water is 5-6 times of medicated powder weight. dried medicated powder will be drawn large quantity of moisture (2-3 is doubly to own wt) when leaching owing to the first time, the leachate of obtaining is minimum, for the second time more, maximum for the third time. three times solution is called total leachate altogether, generally obtain 6-6.6 liter/per kilogram medicated powder, in above composition can obtain (by meansigma methods: 6.3 liters/per kilogram medicated powder) 801.36-1571.22 rises leachate. if concentrate in 1/20 ratio, generally can obtain 0.32 liter of (meansigma methods of 0.3-0.34 liter/per kilogram medicated powder)/per kilogram medicated powder, can obtain 40.70-79.81 by above composition and rise concentrated night. press us 300 milliliters/bottled, can make the strong oral heart liquid of 135.7-266 bottle (Flos Carthami essence-1)-painstaking effort. every milliliter of (Flos Carthami essence-1) oral liquid, by 1000 grams/320 milliliters=3.13 gram Chinese herbal medicine, concentrate in 1/20 ratio then and the medicinal liquid that obtains through boiling extraction. compare with (also giving birth to red). service once sooner or later every day, each 6, only contain medicated powder 3 grams, and (Flos Carthami essence-1), every day also sooner or later respectively once, each 10 milliliters, just need from 3.13 gram X10=31.3 gram Chinese herbal medicine extracting. and be YAOJING, weight is given birth to red 10.43 times for changing, and renders a service considerably beyond 10 times! Here it is, and why we say, (Flos Carthami essence) can be saved critically ill patient's life and thoroughly cure one of most important reason of cardiovascular system diseases! Also be why also living red and Flos Carthami essence is one group, in order to bring into play speciality separately, remedy deficiency separately exactly, just can give full play to the power for the treatment of multiple diseases such as cardiovascular system diseases!

Embodiment 1 according to first content of each component (as Flos Carthami 5-10,5 is first content, 10 then is second content) promptly prepare oral liquid with 127.2 medicine. according in the preparation method (2) one. will make 127.2 medicated powder. by two. in 1. add 5 times to promptly 636.0 kilograms (or litre) water of dose in heater 2. under stirring state, 127.2 kilograms medicated powder are added in the entry then by 3., 4. carry out with 5. operations, just can make 127.2 kilograms of medicated powder and leach medicinal liquid for the first time. and then fully according to three. operational approach is carried out. the just last chitinous amount that adds be 0.5. so, just can make the oral liquid that meets the requirements with 127,7 kilograms medicine.

Experience (all by manual operations) according to our pharmacy: during boiling extraction, if amount of water is 5 times of medicated powder weight. generally obtain 6 liters/per kilogram medicated powder. this composition can obtain 763.2 liters leachate. concentrates in 1/20 ratio, can obtain 39.16 liters (Flos Carthamis-1) (chitin that has added 0,5 kilogram certainly at last) is the painstaking effort health-care oral liquids.

Embodiment 2: according to second content of each component in forming, promptly prepare with 249.4 medicine. according in the preparation method (2) one. will make 249.4 medicated powder. by two. in 1. add 6 times to promptly 1496.46 kilograms (or litre) water of dose in heater 2. under stirring state, 249.4 kilograms medicated powder are added in the entry then by 3., 4. carry out with 5. operations, just can make 249.4 kilograms of medicated powder and leach medicinal liquid for the first time. and then fully according to three. operational approach is carried out. and just last to add chitinous amount be 1. so, just can make the oral liquid that meets the requirements with 250.4 kilograms medicine.

Experience (all by manual operations) according to our pharmacy is 6 times of medicated powder weight as if amount of water, generally obtain 6.6 liters/per kilogram medicated powder, this composition can make 1646.04 liters of leachates. after the ratio in 1/20 concentrates, 82.30 liters of (Flos Carthami essence-1) oral liquids of meeting the requirements can be made, 274.34 bottles of (300 milliliters/bottle) oral liquids can be adorned.

The present invention is used for the treatment of cardiovascular disease and has obtained good effect.Diseases such as the heart failure that a variety of causes is clinically caused, angina pectoris, acute myocarditis, dilated cardiomyopathy have all obtained better curative effect, now from nineteen ninety December～use the present invention during in the JIUYUE, 2007 and treat cardiovascular disease 91 routine clinical effectiveness and be reported as follows.

1 clinical data

1.1 physical data 91 examples are nineteen ninety December～2007 year JIUYUE treatment patient, male's 67 examples wherein, women's 24 examples, 26～81 years old age, average 46 years old.Angina pectoris 21 examples are selected the patient according to the WHO1978 diagnostic criteria, have typical retrosternal pain, and the electrocardiogram performance is inverted for the T ripple, and myocardium enzyme is chemically examined normal person and accounted for 74.6%; Other account for 19.2% for atypical angina pectoris, and the complicated hypertension person accounts for 41%.Myocarditis 19 examples have the forerunner to infect history, and the visible ST-T of electrocardiogram changes, arrhythmia such as the chamber of appearance morning, Fang Zao.Dilated cardiomyopathy 8 examples are according to ultrasoundcardiogram left side chamber 65～70mm, left room 40～45mm, interventricular septum, LVPW hypomotility, left ventricular ejection mark 48%～50%.Heart failure 19 examples, coronary heart disease heart failure 9 examples wherein, rheumatic heart disease heart failure 7 examples, pulmonary heart disease heart failure 3 examples, diagnostic criteria is reduced in 42%～54% according to Doppler echocardiography left ventricular ejection mark, E peak 0.56～0.68m/s, and the A peak is at 0.76～0.85m/s, E/A ratio is inverted, and the prompting left ventricle is shunk and diastolic function all reduces.Coronary atherosclerosis 13 examples, hyperlipidemia 11 examples.

1.2 Therapeutic Method: according to the patient's body constitution and the course of disease, obey the 10-20 milliliter general every day, divides to take for three times.14 days is 1 course of treatment.Take 2 courses of treatment continuously.

1.3 curative effect judging standard

(1) angina pectoris: it is produce effects more than 80% that angina pectoris attacks number of times, buccal sorbitrate number of times reduce; The two reduces 50～80% is effective; The two minimizing＜50% is invalid.

(2) myocarditis: subjective symptoms is obviously alleviated, and electrocardiogram and myocardium enzyme are recovered normal person and be produce effects; It is effective that subjective symptoms and electrocardiogram all have the improver; Subjective symptoms and electrocardiogram all do not have the improver for invalid;

(3) heart failure: alleviate with conscious dyspnea behind the MCA, base of lung mouth rale disappears, and it is produce effects that cardiac function improves the II level; Conscious dyspnea alleviates, and the base of lung is dispersed in wet mouthful rale, and cardiac function improves the I level for effective; Subjective symptoms and cardiac function all do not have be improved as invalid.

(4) dilated cardiomyopathy: symptom is obviously alleviated after the medication, and ultrasonic cardiography illustrates left chamber contractile function to be improved, and the heart of expansion obviously is reduced into produce effects; Subjective symptoms is improved, and the heart of cardiac function and expansion does not have and obviously is reduced into effectively; It is invalid that both all do not have the improver.

(5) coronary atherosclerosis: produce effects: clinical symptoms, sign are obviously improved, and symptom integral reduces 〉=70%, and transcranial Doppler sonography (TCD) index changes 〉=70%; Effectively: clinical symptoms, sign all take a favorable turn, and symptom integral reduces 〉=30%, and the TCD index changes 〉=30%; Invalid: clinical symptoms, sign do not have obvious improvement, even increase the weight of, symptom integral reduces less than 30%, and the TCD index changes less than 30%.

(6) hyperlipidemia: control: clinical symptoms, Signs disappear, and the every inspection of laboratory recovers normal.Produce effects: clinical symptoms, Signs disappear substantially, and lipids detection reaches following wantonly 1 person: TC and descends〉20%, TG descends〉40%, HDL-C rises〉0.26mmol/L (10mg/dl), TC-HDL-G/HDL-C descends〉20%.Effectively: lipids detection reaches following each person: Tc and descends〉10% but＜20%, TG descends〉20% but＜40%, HDL-C rises〉0.14mmol/L (4mg/dl but＜0.26mmol/L (10mg/dl), TC-HDL-C/HDL-C descends〉10% but＜20%.Invalid: treatment back symptom, sign and lipids detection do not have obvious improver.

1.4 therapeutic outcome

Produce effects 17 examples, effective 3 examples in angina pectoris 21 examples;

Produce effects 14 examples in myocarditis 19 examples, effective 5 examples;

Produce effects 4 effective 3 examples in dilated cardiomyopathy 8 examples, invalid 1 example.

Produce effects 14 examples in heart failure 19 examples, effective 3 examples, invalid 2 examples.

Produce effects 11 examples, effective 2 examples in coronary atherosclerosis 13 examples.

Hyperlipidemia 11 example controls 1 example, produce effects 7 examples, effective 3 examples.

The present invention can increase myocardial contraction, improves blood-pumping function; Expansion peripheral blood vessel, coronary artery reduce and penetrate the blood resistance, improve heart output, alleviate heart front and back load, improve cardiac function, to the treating cardiovascular disease definite effect.

Claims (2)

1, a kind of pure Chinese medicinal preparation for the treatment of cardiovascular system diseases is characterized in that making with the raw material of Chinese medicine that contains following weight parts:

Flos Carthami 5-10, Herba Leonuri 10-20, Radix Salviae Miltiorrhizae 4-8, Rhizoma Chuanxiong 4-8, river cattle sunset 2-4, Semen Persicae 3-6, Oletum Trogopterori 2-4, rhizoma sparganic 2-4, Rhizoma Curcumae 2-4, Rhizoma Curcumae Longae 2-4, Sanguis Draxonis 1-2, Radix Clematidis 3-6, Radix Gentianae Macrophyllae 2-4, Radix Angelicae Pubescentis 2-4, Radix Stephaniae Tetrandrae 2-4, Concha Haliotidis 2-4, Concha Ostreae 2-4, Fructus Tribuli 2-4, Ramulus Uncariae Cum Uncis 3-6, Bombyx Batryticatus 1-2, Scorpio 0.2-0.4, Radix Et Rhizoma Rhei 4-8, Herba Ephedrae 2-4, Semen Lepidii (Semen Descurainiae) 2-4, Semen Armeniacae Amarum 2-4, Radix Stemonae 2-4, Bulbus Fritillariae Cirrhosae 4-8, Fructus Trichosanthis 2-4, Arisaema Cum Bile 2-4, Rhizoma Pinelliae 2-4, Rhizoma Cyperi 2-4, Rhizoma Corydalis 2-4, Lignum Aquilariae Resinatum 2-4, Semen Cassiae 2-4, ancient careless 2-4 of summer, Periostracum Cicadae 1-2, Flos Lonicerae 3-6, Flos Chrysanthemi 2-4, Radix Scutellariae 3-6, Rhizoma Coptidis 2-4, Cortex Moutan 2-4, Radix Paeoniae Rubra 4-8, Radix Polygoni Multiflori 4-8, Radix Astragali 4-8.

2, the pure Chinese medicinal preparation of treatment cardiovascular system diseases according to claim 1 is characterized in that making with the raw material of Chinese medicine of following weight parts:

Flos Carthami 5-10, Herba Leonuri 4-8, Radix Salviae Miltiorrhizae 4-8, Rhizoma Chuanxiong 4-8, river cattle sunset 2-4, Semen Persicae 3-6, Oletum Trogopterori 2-4, rhizoma sparganic 2-4, Rhizoma Curcumae 2-4, Rhizoma Curcumae Longae 2-4, Sanguis Draxonis 1-2, Radix Clematidis 3-6, Radix Gentianae Macrophyllae 2-4, Radix Angelicae Pubescentis 2-4, Radix Stephaniae Tetrandrae 2-4, Ganoderma 3-6, Semen Ziziphi Spinosae 3-6, Caulis Polygoni Multiflori 2-4, Concha Haliotidis 2-4, Concha Ostreae 2-4, Herba Apocyni veneti 1-2, Fructus Tribuli 2-4, Pheretima 2-4, Ramulus Uncariae Cum Uncis 3-6, Bombyx Batryticatus 1-2, Scorpio 0.2-0.4, Radix Et Rhizoma Rhei 4-8, Herba Ephedrae 2-4, Fructus Perillae 2-4, Semen Lepidii (Semen Descurainiae) 2-4, Semen Armeniacae Amarum 2-4, Radix Stemonae 2-4, Bulbus Fritillariae Cirrhosae 4-8, Fructus Trichosanthis 2-4, Arisaema Cum Bile 2-4, Rhizoma Pinelliae 2-4, Rhizoma Cyperi 2-4, Rhizoma Corydalis 2-4, Lignum Aquilariae Resinatum 2-4, Semen Cassiae 2-4, ancient careless 3-6 of summer, Periostracum Cicadae 1-3, Flos Lonicerae 3-6, Flos Chrysanthemi 2-4, Radix Scutellariae 3-6, Rhizoma Coptidis 2-4, Radix Gentianae 2-4, Cortex Phellodendri 2-4, Cortex Moutan 2-4, Radix Paeoniae Rubra 4-8, Radix Polygoni Multiflori 4-8, Radix Astragali 4-8, chitin 0.5-1.