CN102430067A - Method for preparing medicament for treating hypertension - Google Patents
Method for preparing medicament for treating hypertension Download PDFInfo
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- CN102430067A CN102430067A CN2011104508480A CN201110450848A CN102430067A CN 102430067 A CN102430067 A CN 102430067A CN 2011104508480 A CN2011104508480 A CN 2011104508480A CN 201110450848 A CN201110450848 A CN 201110450848A CN 102430067 A CN102430067 A CN 102430067A
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Abstract
The invention relates to a method for preparing a medicament for treating hypertension. The medicament is prepared from the following components in parts by weight: 5 parts of draconis sanguis, 5 parts of mulberry twigs, 5 parts of scorpion, 6 parts of frankincense, 10 parts of salvia miltiorrhiza, 10 parts of spica prunellae, 10 parts of uncaria, 7 parts of corn silk, 10 parts of lotus leaf and 10 parts of panicled swallowwort root. The preparation method of the medicament comprises the steps of: respectively crushing the components into fine powder, sieving by a 100-mesh sieve, weighing according to the formula ratio, uniformly mixing, pilling to obtain wet pills, conveying to a hot air circulation oven, drying at 60 DEG C for 8-10 hours until the water content is lower than 7%, sterilizing and bottling. Through a great amount of clinical applications prove that the medicament provided by the invention can treat hypertension, has the actions of regulating, alleviating, controlling, improving and curing the hypertension for human, has the advantages of short course of treatment, good curative effect, safety and reliability, no toxic or side effect, wide medicine sources, simple preparation process, and reasonable, scientific and precise formula, and is a safe and effective pure traditional Chinese medicine preparation.
Description
Technical field
The present invention relates to a kind of is the method for feedstock production medicine with the Chinese herbal medicine, particularly a kind of method of treating hypertension drug for preparing.
Background technology
Hypertension is a long-term chronic disease of progress gradually; The patient often has symptoms such as dizziness, headache, nervous, insomnia; As can not in time treat, hypertension causes a series of serious threat life such as the heart, brain, kidney and vascular lesion and healthy complication the most at last.
Hypertension is to be characteristic with the arteriotony rising, with the systemic disease of organ dysfunction property such as heart, blood vessel, brain and kidney or organic change.In China, the main directly complication of hypertension is a cerebrovascular, especially cerebral hemorrhage.The primary hypertension patient that one group of 312 example is in hospital was followed up a case by regular visits to through 15 years-18 years for a long time, because the heart, brain, dead 97 examples of kidney complication account for 74.6% of whole causes of the death.In 596 routine senile hypertensions follow-up observation in perspective 27 months research, the heart, cerebrovascular accumulation incidence rate are 68.79%, and cerebrovascular accumulation incidence rate is 36.91%.Research shows that blood pressure is high more, and the incidence rate of complication is also high more.
In addition, hypertension also can cause the multiple pathological changes of the heart, brain, kidney and blood vessel, and serious threat life such as left ventricular hypertrophy, congestive heart failure, dissection of aorta, chronic renal failure and healthy complication take place.The hyperpietic should in time treat.
China once carried out 3 sampling survey to hypertension, and the result shows: per 10 years of China's hypertension prevalence rises about 25%, and present national patient's estimated number surpasses 100,000,000.Therefore, strengthen the propaganda to the high blood pressure disease control, help controlling the hypertension prevalence of continuous rising, prevention and control hypertension complication reduce disability rate and mortality rate, improve patient's quality of life.
At present, treating hypertensive conventional method is to take Western medicine depressor, still; Doctor trained in Western medicine depressor is that toxicity is very important; " being three fens poison of medicine ", these words that everyone knows about it are used on the depressor and are fit to equally, though Western medicine depressor can be controlled blood pressure for the moment; Not allowing increased blood pressure, still is that human body is had bigger injury but take for a long time.This is because a large amount of drug metabolism toxin that is produced by depressor can be deposited on the blood vessel wall, takes how sedimentary also just manyly more, finally causes sclerosis of blood vessels, attenuation, becomes fragile; Add depressor through powerful blood vessel dilating to reach quick blood pressure lowering; Therefore must making originally, hardened blood vessel becomes fragile more; And this will seriously damage important human organs such as the heart, brain, liver, kidney; And aggravate the generation of complication, finally jeopardize hyperpietic's life.Simultaneously, the hypertensive conventional method of traditional treatment is to be target through the Western medicine blood pressure lowering, can only controlling blood pressure, there are EDD short and chemical sproof major side effects and shortcoming.Long-term clothes depressor, patient understands depressed, feels depressed slowness of thinking, inefficiency.The toxic and side effects of medicine at first can influence the digestive function of human body, causes nausea, anorexia, and xerostomia, abdominal distention, diarrhea, weight person causes peptic ulcer, gastrorrhagia; Take medicine for a long time, that the patient feels is dizzy, drowsiness, headache, fever sensation of the face, nervous, blurred vision etc.But at present on the market Chinese medicine preparation or curative effect can not be satisfactory, or curative effect is pretty good but have certain toxic and side effects.
Summary of the invention
The objective of the invention is to overcome the above-mentioned deficiency of prior art; Can effectively bring high blood pressure down and provide a kind of, safety has no side effect the blood pressure lowering stable and durable; The complication that can reduce hypertension takes place; Easy to use, price is suitable, therapeutic effect is good, cost is low, have no side effect prepare the method for treating hypertension drug.
Technical scheme of the present invention is: a kind of method of treating hypertension drug for preparing, and its drug component consumption is:
Sanguis Draxonis 5-10 weight portions, Ramulus Mori 5-8 weight portions, Scorpio 5-15 weight portions, Olibanum 6-15 weight portions, Radix Salviae Miltiorrhizae 10-20 weight portions, Spica Prunellae 10-20 weight portions, Ramulus Uncariae Cum Uncis 10-20 weight portions, Stigma Maydis 7-15 weight portions, Folium Nelumbinis 10-20 weight portions, Radix Cynanchi Paniculati 10-20 weight portions;
Its preparation method is: with the said medicine component through the screening, according to " Chinese pharmacopoeia (2010 editions) prepared slices of Chinese crude drugs processing specification processes, and pulverize separately becomes fine powder; Cross 100 mesh sieves, by above-mentioned formula proportion weigh, mixing, pill, make the wet pill of G4 millimeter after; The ball that will wet changes in the heated-air circulation oven, 60 ℃ dry 8-10 hours down, be lower than 7% to water content; Sterilization, bottling.
The further technical scheme of the present invention is: the drug component consumption is: Sanguis Draxonis 5 weight portions, Ramulus Mori 5 weight portions, Scorpio 5 weight portions, Olibanum 6 weight portions, Radix Salviae Miltiorrhizae 10 weight portions, Spica Prunellae 10 weight portions, Ramulus Uncariae Cum Uncis 10 weight portions, Stigma Maydis 7 weight portions, Folium Nelumbinis 10 weight portions, Radix Cynanchi Paniculati 10 weight portions.
The further again technical scheme of the present invention is: the drug component consumption is: Sanguis Draxonis 10 weight portions, Ramulus Mori 8 weight portions, Scorpio 15 weight portions, Olibanum 15 weight portions, Radix Salviae Miltiorrhizae 20 weight portions, Spica Prunellae 20 weight portions, Ramulus Uncariae Cum Uncis 20 weight portions, Stigma Maydis 15 weight portions, Folium Nelumbinis 20 weight portions, Radix Cynanchi Paniculati 20 weight portions.
Medicine of the present invention is tan solid preparation, the fragrant little hardship of gas.Chinese medicine be China over the past thousands of years, the summary of experience that millions upon millions of people struggle with disease is an important component part of the valuable cultural heritage of China.Chinese medicine has accumulated very abundant experiences in diagnosis and treatment in the long term medical practice, formed unique theoretical system.Medicine of the present invention is as Chinese medicine old and well-known family's inventor's secret prescription handed down in the family from generation to generation, and the good recipe for treatment hypertension through liver metabolism, excites Primordial Qi; Promoting flow of QI and blood, blood circulation promoting and blood stasis dispelling, channels and collaterals dredging; QI and blood is smooth, purifies the blood, and the cardiovascular disease that is caused by three-hypers is improved fast.Be used for the clinical treatment hyperpietic for over ten years, evident in efficacy.Compared with prior art, have following advantage:
1, the good flowing properties of medicine of the present invention is convenient to flow in the blood and absorb, and has solved the world-famous puzzle of the through focus of medicine.
2, compatibility, technology have guaranteed the effective content and the concentration of medicine, make the medicine active ingredient exceed general medicine 6-9 doubly.
3, set up whole cleaning,, can shake and peel off the fat poison dirt and chemical poison dirt that is deposited on the blood vessel wall, make blood vessel wall be able to reparation through dirty blood is filtered and purifies; Again recover smooth and elasticity, the stifled lumen of vessels of the stasis of blood is broadened, blood fluidity is strengthened; Improve intracellular metabolite circulation, comprehensively promoting flow of QI and blood, excite vigour, solve a recurrence difficult problem; The treatment vital base and primordial QI consolidating is adjusted the immunity of organism metabolism comprehensively, the real purpose that realizes radical cure and disease preventing and treating recurrence.
Ancients' cloud: the vital organs of the human body, extremity bones of the body collectively, face nine orifices, through having expressly; But how to depend on? " interior warp " said: " its for down, stimulating Qi of meridian, promoting flow of QI and blood, blood circulation promoting and blood stasis dispelling, improve local microcirculation and make blood accelerate channels and collaterals dredging; QI and blood is smooth; improving body's immunity has very good effect, take for a long time safe and reliable, no dependence.To the human non-toxic side effect.Luo Shi often says: " be doctor's road, first must be sensible, face card know sick, the affair art its because of, make laws then, the side of sending, compatibility, an amount of, but sick amorphous, promptly become when knowing, also to know and keep.So " pellet stimulates the menstrual flow " effect is unique taking.
The present invention confirms through a large amount of clinical practices, can treat vascular hypertension, the effect that really mankind is had mediation, alleviation, control, improvement, heals entirely; Not only short treating period, good effect, safe and reliable, no any poison pair are done; And medicine source wide material sources, preparation technology is simple, reasonable recipe; Scientific and precise is a kind of pure Chinese medicinal preparation safely and effectively.
In the drug component of the present invention:
Sanguis Draxonis: sweet, salty, flat, GUIXIN, Liver Channel.Has the effect that blood stasis dispelling presses down hemostasia and promoting granulation surely.
Ramulus Mori: little hardship, put down, return Liver Channel.Has wind-damp dispelling, the effect in sharp joint.
Scorpio: hot, flat, poisonous, return Liver Channel.Have to fully recover from an illness in the endogenous wind stopping town, the effect of dispersing pathogen accumulation, removing obstruction in the collateral to relieve pain.
Olibanum: suffering, hardship, temperature, GUIXIN gallbladder spleen channel has the effect of blood-activating and qi-promoting pain relieving.
Radix Salviae Miltiorrhizae: bitter, be slightly cold, GUIXIN, Liver Channel.Have stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, the effect of the relieving restlessness that clears away heart-fire.
Spica Prunellae: hot, cold, bitter, return the liver and gall warp.Having relieves inflammation or internal heat makes eye bright, the effect of mass dissipating and swelling eliminating.
Ramulus Uncariae Cum Uncis: sweet, cold, the heat clearing away suppressing the hyperactive liver has the arresting convulsion that relieves dizziness, high fever, infantile convulsions, epilepsy, etc., and controls the effect of headache, dizzy, hypertension.
Stigma Maydis: sweet, light, flat, for bladder liver and gall warp, have promoting the function of the gallbladder to alleviate jaundice, inducing diuresis to remove edema, the effect of blood pressure lowering.
Folium Nelumbinis: bitter, flat, return liver, spleen, stomach warp.Effect with heat-clearing and toxic substances removing, sending up the lucid YANG, cooling blood for hemostasis.
Remove long minister in ancient times: sweet, acid is trembled with fear, and returns liver, heart channel.The effect of have cooling blood and removing stasis, dispeling the wind.
Below come further to set forth beneficial effect of the present invention through Test Example.
Embodiment 1:
A kind of method of treating hypertension drug for preparing, its drug component consumption is:
Sanguis Draxonis 5 weight portions, Ramulus Mori 5 weight portions, Scorpio 5 weight portions, Olibanum 6 weight portions, Radix Salviae Miltiorrhizae 10 weight portions, Spica Prunellae 10 weight portions, Ramulus Uncariae Cum Uncis 10 weight portions, Stigma Maydis 7 weight portions, Folium Nelumbinis 10 weight portions, Radix Cynanchi Paniculati 10 weight portions;
Its preparation method is: with the said medicine component through the screening, according to " Chinese pharmacopoeia (2010 editions) prepared slices of Chinese crude drugs processing specification processes, and pulverize separately becomes fine powder; Cross 100 mesh sieves, by above-mentioned formula proportion weigh, mixing, pill, make the wet pill of G4 millimeter after; The ball that will wet changes in the heated-air circulation oven, 60 ℃ dry 8-10 hours down, be lower than 7% to water content; Sterilization, bottling.
Embodiment 2:
A kind of method of treating hypertension drug for preparing, its drug component consumption is:
Sanguis Draxonis 10 weight portions, Ramulus Mori 8 weight portions, Scorpio 15 weight portions, Olibanum 15 weight portions, Radix Salviae Miltiorrhizae 20 weight portions, Spica Prunellae 20 weight portions, Ramulus Uncariae Cum Uncis 20 weight portions, Stigma Maydis 15 weight portions, Folium Nelumbinis 20 weight portions, Radix Cynanchi Paniculati 20 weight portions;
Its preparation method is: with the said medicine component through the screening, according to " Chinese pharmacopoeia (2010 editions) prepared slices of Chinese crude drugs processing specification processes, and pulverize separately becomes fine powder; Cross 100 mesh sieves, by above-mentioned formula proportion weigh, mixing, pill, make the wet pill of G4 millimeter after; The ball that will wet changes in the heated-air circulation oven, 60 ℃ dry 8-10 hours down, be lower than 7% to water content; Sterilization, bottling.
Test Example: the embodiment of the invention 1 gained clinical drug is observed.
(1) physical data
All case 437 examples are carried out observation of curative effect.Male's 278 examples wherein, women's 159 examples.Age 30-80 year.
(2) Therapeutic Method
Get embodiment 1 gained medicine, every bag of 8g gets 2 bags of 16g altogether every day, takes at twice, and each 1 bag, one month is a course of treatment, treats 1-3 the course of treatment altogether.
(3) efficacy assessment standard
Cure: symptom all disappears; Main physics and chemistry detects index and is normally.
Take a turn for the better: symptomatology is eliminated or cardinal symptom is eliminated; It is normal basically that physics and chemistry detects index.
Control: cardinal symptom is eliminated basically; Main physics and chemistry detects index and makes moderate progress.
Invalid: and compare the each side no change or the person of increasing the weight of before the treatment.
Hypertension therapy statistical effect table of the present invention:
| Disease | Number | The range of age | The man | The woman | Cure | Take a turn for the better | Control | Invalid | Remarks |
| Hypertension | 437 | 30-80 | 278 | 159 | 335 | 79 | 23 | 0 | ? |
Clinical case:
Example one: Cai, the man, 70 years old, on April 27th, 2009, readme: sudden illness, inspection blood pressure 150-185 is in hospital one month, and relatives look after when leaving hospital, and feel bad really, listen friend to introduce afterwards.Take medicine of the present invention, concrete instructions about how to take medicine, each 8g, 2 times on the one, one month is a course of treatment.After taking a course of treatment, blood pressure is steady, through the time more than a year, eats the red medicine that stimulates the menstrual flow, and health is got well basically, can walk also competent light work, blood pressure stabilization (blood pressure 85-135).
Example two: Lee, the man, 57 years old, readme on March 13 in 2010: once catch a cold, dizzy, general malaise were removed examination in hospital, and (the blood pressure 110-165) that the hypertension of saying so causes opens Western medicine in hospital and eat a little times, and blood pressure does not lower, again and again.Introduced through friend afterwards and took medicine of the present invention, concrete instructions about how to take medicine, each 8g, 2 times on the one, one month is a course of treatment.Through after taking a course of treatment, go to hospital to check, blood pressure stabilization keeps blood pressure stabilization till now at 80-120 always.
Example three: flood certain, the woman, 36 years old, on April 12nd, 2011, readme: flu once, dizziness, general malaise is gone to a hospital to see a doctor, the doctor gives me measuring blood pressure 110-170.Open a little medicines through hospital, eaten quite a lot of times, whenever just removed the Community Health Station measuring blood pressure at a distance from 2 days, unstable blood pressure is fixed, and today, survey was this number; Surveying tomorrow is that number, will take medicine everyday, and again and again, it is quite good to introduce hypertension therapy effect of the present invention through friend; Pure Chinese medicinal preparation is free from side effects, and begins to take medicine of the present invention, every day 2 times; Each 8g, take a course of treatment after, to the Community Health Station measuring blood pressure, blood pressure is 85-130.Took continuously 6 months, blood pressure is held stationary always.
Example four: Wei, man, 78 years old, readme: in JIUYUE, 2007, once unfortunate falling; Send county people's hospital's first aid to, hypertension 120-180 is said in an inspection, and some times of hospitalization, blood pressure is at 100-155; After going home, eat depressor, blood pressure is not really stable everyday, the time high when low.On October 13rd, 2008, introduce through comrade, begin to take medicine of the present invention, every day 2 times, each 8g, take a course of treatment after, blood pressure remains on 85-130.
Example five: Jiang, the man, 70 years old, readme on April 27 in 2009: sudden illness, inspection blood pressure 110-185 is in hospital one month, and relatives look after when leaving hospital, and feel bad really.Listen friend to introduce afterwards, took medicine of the present invention, concrete instructions about how to take medicine, each 8g, 2 times on the one, one month is a course of treatment.After taking a course of treatment, life can be taken care of oneself, and lover continues the time more than a year with stroll, and health recovers basically, can walk also competent light work, and blood pressure stabilization is at 90-135.
Example six: Liao, the woman, 67 years old, readme on July 23 in 2009: often headache, tinnitus, poor sleep goes the hospital outpatient inspection, blood pressure is always unstable, have Western medicine everyday, three times on the one, do not eat blood pressure with regard on be coming.On October 13rd, 2010, introduce through friend, stopped Western medicine, take medicine of the present invention, concrete instructions about how to take medicine, each 8g, 2 times on the one, one month is a course of treatment.After taking a course of treatment, removed commune hospital's measuring blood pressure once in per two days, blood pressure continued to take medicine of the present invention 6 months within 85-130, now blood pressure held stationary (80-120).
Claims (3)
1. one kind prepares the method for treating hypertension drug, it is characterized in that the drug component consumption is:
Sanguis Draxonis 5-10 weight portions, Ramulus Mori 5-8 weight portions, Scorpio 5-15 weight portions, Olibanum 6-15 weight portions, Radix Salviae Miltiorrhizae 10-20 weight portions, Spica Prunellae 10-20 weight portions, Ramulus Uncariae Cum Uncis 10-20 weight portions, Stigma Maydis 7-15 weight portions, Folium Nelumbinis 10-20 weight portions, Radix Cynanchi Paniculati 10-20 weight portions;
Its preparation method is: with the said medicine component through the screening, according to " Chinese pharmacopoeia (2010 editions) prepared slices of Chinese crude drugs processing specification processes, and pulverize separately becomes fine powder; Cross 100 mesh sieves, by above-mentioned formula proportion weigh, mixing, pill, make the wet pill of G4 millimeter after; The ball that will wet changes in the heated-air circulation oven, 60 ℃ dry 8-10 hours down, be lower than 7% to water content; Sterilization, bottling.
2. the method for treating hypertension drug for preparing according to claim 1 is characterized in that the drug component consumption is: Sanguis Draxonis 5 weight portions, Ramulus Mori 5 weight portions, Scorpio 5 weight portions, Olibanum 6 weight portions, Radix Salviae Miltiorrhizae 10 weight portions, Spica Prunellae 10 weight portions, Ramulus Uncariae Cum Uncis 10 weight portions, Stigma Maydis 7 weight portions, Folium Nelumbinis 10 weight portions, Radix Cynanchi Paniculati 10 weight portions.
3. the method for treating hypertension drug for preparing according to claim 1 is characterized in that the drug component consumption is: Sanguis Draxonis 10 weight portions, Ramulus Mori 8 weight portions, Scorpio 15 weight portions, Olibanum 15 weight portions, Radix Salviae Miltiorrhizae 20 weight portions, Spica Prunellae 20 weight portions, Ramulus Uncariae Cum Uncis 20 weight portions, Stigma Maydis 15 weight portions, Folium Nelumbinis 20 weight portions, Radix Cynanchi Paniculati 20 weight portions.
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| CN201110450848.0A CN102430067B (en) | 2011-12-29 | 2011-12-29 | Method for preparing medicament for treating hypertension |
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| CN201110450848.0A CN102430067B (en) | 2011-12-29 | 2011-12-29 | Method for preparing medicament for treating hypertension |
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1686510A (en) * | 2005-04-14 | 2005-10-26 | 赵宏伟 | Ready prepared Chinese medicine for preventing and treating brain apoplexia |
| CN101396498A (en) * | 2008-10-25 | 2009-04-01 | 宁甲保 | Traditional Chinese medicine preparation for treating cerebrovascular disease |
| CN101396543A (en) * | 2008-10-25 | 2009-04-01 | 宁甲保 | Pure traditional Chinese medicine preparation for treating cardio-cerebrovascular disease |
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- 2011-12-29 CN CN201110450848.0A patent/CN102430067B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1686510A (en) * | 2005-04-14 | 2005-10-26 | 赵宏伟 | Ready prepared Chinese medicine for preventing and treating brain apoplexia |
| CN101396498A (en) * | 2008-10-25 | 2009-04-01 | 宁甲保 | Traditional Chinese medicine preparation for treating cerebrovascular disease |
| CN101396543A (en) * | 2008-10-25 | 2009-04-01 | 宁甲保 | Pure traditional Chinese medicine preparation for treating cardio-cerebrovascular disease |
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