CN103041361A - Medicament for treating three-high disease (high cholesterol, high blood pressure, high blood sugar) and preparation method thereof - Google Patents

Medicament for treating three-high disease (high cholesterol, high blood pressure, high blood sugar) and preparation method thereof Download PDF

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CN103041361A
CN103041361A CN2013100169636A CN201310016963A CN103041361A CN 103041361 A CN103041361 A CN 103041361A CN 2013100169636 A CN2013100169636 A CN 2013100169636A CN 201310016963 A CN201310016963 A CN 201310016963A CN 103041361 A CN103041361 A CN 103041361A
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parts
radix
medicine
fructus
rhizoma
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CN103041361B (en
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闫位国
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Guangxi Dongxing City Innovation Characteristic Medical Science & Technology Development Co Ltd
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Guangxi Dongxing City Innovation Characteristic Medical Science & Technology Development Co Ltd
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Abstract

The invention provides a medicament for treating three high diseases (high cholesterol, high blood pressure, high blood sugar) and a preparation method thereof. The medicament is formed by mixing 24 Chinese herb medicines such as unprocessed monkshood, tribulus terrestris, pseudo-ginseng, black aconite, hawthorn, prepared fleece flower roots, cherokee rose fruits, apocynum venetum, leech, fried jujube kernel. The preparation method comprises the following steps of: pulverizing the medicines to be fine powder or performing water decoction to extract and prepare a thick paste; adding conventional auxiliary materials into the thick paste to prepare different preparations. According to the medicament, by virtue of scientific matching of the multiple medicines and comprehensive treatment, the effective components of the medicament can rapidly enter a blood circulating system to clear away lipid and cholesterol stagnated in a vessel, promote excretion, inhibit aggregation of blood cells, reduce arteriosclerosis and anti-thrombosis, and improve functions of organs, so that the three-high disease can be cured quickly, and patients can be recovered.

Description

A kind of medicine for the treatment of three-hypers disease and preparation method thereof
Technical field
The invention belongs to technical field of Chinese medicines, be specifically related to a kind of medicine for the treatment of three-hypers disease and preparation method thereof.
Background technology
Three-hypers disease refers to hypertension, hyperglycemia, hyperlipidemia, and they are " affluenza " that modern society is derived from, and possible individualism also may be interrelated.Three-hypers disease can have no symptom in early days, and also no abnormalities feel is usually just found when doing physical examination, and such as untimely discovery, this disease develops into and can form serious disease late period, even threat to life.
Hypertension is a kind of chronic disease take the lasting rising of arteriotony as main manifestations, often causes the pathological changes of the vitals such as the heart, brain, kidney and corresponding consequence occurs.Can show as in early days headache, dizziness, tinnitus, cardiopalmus, dim eyesight, the symptom such as absent minded, the later stage blood pressure often continues in higher level, and impaired with organs such as brain, the heart, kidneys.
Hyperglycemia is because insulin is relative or absolute not enough, makes a kind of chronic, the lifelong property disease of the nutrient Developmental and Metabolic Disorder such as carbohydrate, fat, protein in the body.This disease can cause multiple complications, can cause systemic disease when serious, makes that the people is disabled, blinding, even causes death.
Hyperlipidemia can give rise to diseases, and comprises coronary atherosclerosis, heart infarction, hypertensive cardiopathy, cardiomyopathy, cerebrovascular, cerebral arteriosclerosis, cerebral thrombosis, liver cirrhosis, renal arteriosclerosis, diabetes etc., serious harm people life and health.
The most of in the market supply takes multi-medicament just for the medicine of a certain single disease in the three-hypers disease simultaneously for the needs of patients of suffering from simultaneously the various disease conditions in hypertension, hyperlipidemia, the hyperglycemia, brought great inconvenience to the patient.These medicines are generally in the majority with Western medicine, although the rapid relief of symptoms of Western medicine, relapse rate is high, and will rebound after the drug withdrawal, must uninterruptedly take medicine for a long time, to the patient with larger financial burden.Simultaneously, the Western medicine toxic and side effects is larger, and long-term prescription also can cause certain infringement to patient body.
Summary of the invention
The technical problem to be solved in the present invention provides a kind of medicine for the treatment of three-hypers disease and preparation method thereof, and this medicine has the blood pressure of accent, blood fat reducing, hypoglycemic effect, and rapid-action, lasting medicine does not recur after the drug withdrawal and do not rebound safe without toxic side effect.
Technical scheme provided by the invention is a kind of medicine for the treatment of three-hypers disease, and it is made by the raw material of following weight portion:
500~1000 parts of Radix Aconiti Lateralis, 500~1000 parts of Fructus Tribulis, 540~1000 parts in Radix Notoginseng, 100~400 parts of Radix Aconiti Lateralis Preparatas, 500~1000 parts of Fructus Crataegis, 250~500 parts of Radix Polygoni Multiflori Preparata, 250~500 parts of Fructus Rosae Laevigatae, 250~500 parts of Herba Apocyni venetis, 180~360 parts of Hirudos, 450~900 parts of Semen Ziziphi Spinosae (parched)s, 300~600 parts of Rhizoma Acori Graminei, 300~600 parts of Rhizoma Chuanxiongs, 900~1000 parts of Caulis Polygoni Multiflori, 450~900 parts of Concha Ostreaes, 300~600 parts of Radix Angelicae Sinensis, 500~1000 parts of Radix Salviae Miltiorrhizaes, 250~500 parts of Concretio silicea Bambusae seu schizostachyi, 250~500 parts of Cortex Lycii, 250~500 parts in sulfur, 500~1000 parts of Radix Ilicis Pubescentiss, 50~100 parts of Herba Asaris, 100~300 parts of Ramulus Cinnamomi, 100~200 parts of Cortex Cinnamomis, 100~200 parts of Rhizoma Zingiberiss.
Preferred weight part of above-mentioned raw materials is:
800 parts of Radix Aconiti Lateralis, 700 parts of Fructus Tribulis, 850 parts in Radix Notoginseng, 250 parts of Radix Aconiti Lateralis Preparatas, 700 parts of Fructus Crataegis, 370 parts of Radix Polygoni Multiflori Preparata, 390 parts of Fructus Rosae Laevigatae, 400 parts of Herba Apocyni venetis, 280 parts of Hirudos, 750 parts of Semen Ziziphi Spinosae (parched)s, 450 parts of Rhizoma Acori Graminei, 400 parts of Rhizoma Chuanxiongs, 950 parts of Caulis Polygoni Multiflori, 800 parts of Concha Ostreaes, 500 parts of Radix Angelicae Sinensis, 700 parts of Radix Salviae Miltiorrhizaes, 400 parts of Concretio silicea Bambusae seu schizostachyi, 350 parts of Cortex Lycii, 380 parts in sulfur, 750 parts of Radix Ilicis Pubescentiss, 80 parts of Herba Asaris, 200 parts of Ramulus Cinnamomi, 160 parts of Cortex Cinnamomis, 150 parts of Rhizoma Zingiberiss.
The medicine for the treatment of three-hypers disease of the present invention, its dosage form can be medically acceptable any dosage forms, specifically can be pill, granule or capsule.
The present invention also provides the preparation method of the medicine of above-mentioned treatment three-hypers disease, may further comprise the steps:
1) takes by weighing each raw material for standby by prescription;
2) Radix Aconiti Lateralis, Radix Aconiti Lateralis Preparata and Herba Asari are placed container, the decocting that adds 8~12 times of the weight of feeding intake boils 1~2h, filters, and gets filtrate for later use;
3) Radix Notoginseng and Hirudo are cleaned, oven dry grinds to form fine powder for subsequent use;
4) sulfur is ground to form fine powder for subsequent use;
5) with Fructus Tribuli, Fructus Crataegi, Radix Polygoni Multiflori Preparata, Fructus Rosae Laevigatae, Herba Apocyni veneti, Semen Ziziphi Spinosae (parched), Rhizoma Acori Graminei, Rhizoma Chuanxiong, Caulis Polygoni Multiflori, Concha Ostreae, Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae, Concretio silicea Bambusae seu schizostachyi, Cortex Lycii, Radix Ilicis Pubescentis, Ramulus Cinnamomi, Rhizoma Zingiberis and Cortex Cinnamomi are cleaned and are placed in the container, decoct with water 1~3 time, each water that adds 6~20 times of raw material gross weights, each 1~2h that decocts, merge decoction liquor, filter medicinal residues, relative density was 1.06~1.14 extractum when filtrate was concentrated into 50~70 ℃, the fine powder and the step 2 that add again step 3) and step 4)) filtrate, mixing, making as required different preparations, specifically can be pill, granule or capsule.
Granularity 100~300 orders of fine powder described in the step 3) of said method and the step 4).
The pharmaceutical characteristic of each raw material of the present invention is:
Radix Aconiti Lateralis, acrid in the mouth, sweet, extremely hot in nature, GUIXIN, kidney, spleen channel, recuperating depleted YANG and rescuing the patient from collapse, supporing yang, the dispersing cold for relieving pain of benefit fire;
Fructus Tribuli, acrid in the mouth, hardship, slightly warm in nature is returned Liver Channel, the suppressing the hyperactive liver resolving depression, promoting blood circulation by removing wind makes eye bright, and is antipruritic;
Radix Notoginseng, sweet in the mouth, little hardship, warm in nature, return Liver Channel, stomach warp, heart channel, lung meridian, large intestine channel, hemostasis, loose blood, analgesic therapy;
Radix Aconiti Lateralis Preparata, acrid in the mouth, sweet, extremely hot in nature, GUIXIN, kidney, spleen channel, recuperating depleted YANG and rescuing the patient from collapse, mend fire supporing yang, by wind-cold damp pathogen;
Fructus Crataegi, sweet in the mouth, acid, slightly warm in nature enters spleen, stomach, Liver Channel, promoting digestion and invigorating the stomach, activating blood circulation to dissipate blood stasis, convergence dysentery relieving;
Radix Polygoni Multiflori Preparata, bitter in the mouth, sweet, puckery, warm in nature, flat is returned liver, the heart, kidney channel, invigorating the liver and kidney, benefiting essence-blood, black beard and hair, bone and muscle strengthening, the turbid blood fat reducing of change;
Fructus Rosae Laevigatae, sour in the mouth, sweet, puckery, property is flat, returns kidney, bladder, large intestine channel, astringing intestine to stop diarrhea, controlling nocturnal emission with astringent drugs, stopping leak dysentery, urine reducing;
Herba Apocyni veneti, sweet in the mouth, little hardship, cool in nature, return Liver Channel, heat clearing away suppressing the hyperactive liver, inducing diuresis to remove edema;
Hirudo, the master gathers by stagnant blood, blood stasis, removing blood stasis removing food stagnancy;
Semen Ziziphi Spinosae (parched), sweet in the mouth, acid, property is flat, GUIXIN warp, spleen channel, Liver Channel, gallbladder meridian, mind tranquilizing and the heart calming, nourishing the liver, arresting sweating;
Rhizoma Acori Graminei, acrid in the mouth, hardship, warm in nature, GUIXIN, stomach warp, removing dampness appetizing, the eliminating phlegm of having one's ideas straightened out, refreshment Fructus Alpiniae Oxyphyllae;
Rhizoma Chuanxiong, acrid in the mouth, warm in nature is returned liver, gallbladder, pericardium channel, blood circulation promoting and blood stasis dispelling, activating QI to alleviate the depression, wind-expelling pain-stopping;
Caulis Polygoni Multiflori, sweet in the mouth, little hardship, property is flat, nourishes heart, calms the nerves, collateral dredging, dispels the wind;
Concha Ostreae, salty in the mouth, cold nature are returned liver, gallbladder, kidney channel, convergence, calmness, detoxifcation, analgesia;
Radix Angelicae Sinensis, sweet in the mouth, hardship, suffering, warm in nature, return liver, the heart, spleen channel, menstruction regulating and pain relieving, moisturize laxation;
Radix Salviae Miltiorrhizae, bitter in the mouth, property is flat, tepor, enters the heart, Liver Channel, promoting blood flow to regulate menstruation, stasis-dispelling and pain-killing, removing heat from blood eliminating carbuncle, the relieving restlessness that clears away heart-fire, nourishing blood to tranquillize the mind;
Concretio silicea Bambusae seu schizostachyi, acrid in the mouth, property are put down, and enter lung, Liver Channel, relieving cough and reducing sputum, regulating QI to relieve pain, relieving convulsion;
Cortex Lycii, sweet in the mouth, cold in nature enters lung, liver, kidney channel, and removing heat from blood is except steaming, lung heat clearing pathogenic fire reducing;
Sulfur, sour in the mouth, warm in nature takes orally and can mend fire, supporing yang, relieving constipation;
Radix Ilicis Pubescentis, mildly bitter flavor, sweet, property is flat, enters lung, liver, large intestine channel, blood circulation promoting and blood stasis dispelling, heat-clearing and toxic substances removing, expelling phlegm for arresting cough;
Herba Asari, acrid in the mouth, warm in nature is returned lung meridian, kidney channel, heart channel, Liver Channel, gallbladder meridian, spleen channel, the cold expelling that induces sweat, wind-expelling pain-stopping, warming the lung to resolve fluid-retention, sensible;
Ramulus Cinnamomi, acrid in the mouth, sweet, warm in nature, enter liver, kidney, urinary bladder channel, expelling cold and relieving exterior syndrome, promoting the flow of QI-blood by warming the meridian, activating YANG and prormoting functioning of QI;
Cortex Cinnamomi, acrid in the mouth, sweet, extremely hot in nature is returned kidney, spleen, the heart, Liver Channel, diaphoresis expelling pathogenic factors from muscles, promoting the flow of QI-blood by warming the meridian;
Rhizoma Zingiberis, acrid in the mouth, hot in nature is returned spleen, stomach, the heart, lung meridian, and warming spleen and stomach for dispelling cold, recuperating depleted YANG are promoted blood circulation, dampness expectorant, warming the lung to resolve fluid-retention.
The instructions of taking of medicine of the present invention is: take the medicine that is equivalent to crude drug 6~18g weight every day, take, cold boiled water takes minutes for 3 times, in ante cibum or to take effect half an hour after meal better, 30 days is a course for the treatment of, and most of patient takes 3 courses for the treatment of and can cure.
The kinds of traditional Chinese medicines flavor raw material that adopts of the present invention, the science compatibility, comprehensive measure, can make effective ingredient enter rapidly blood circulation, short time intramedullary expansion vessel softening, increase blood vessel elasticity, increase the blood vessel perfusion flow, remove the lipid and the cholesterol that are retarded by silt in the blood vessel, blocking-up thrombosis, suppress hematoblastic gathering, alleviate arteriosclerosis, and then recover liver, kidney, the heart, the normal physiological function of each organ such as brain, has preferably blood pressure lowering, blood fat reducing, blood sugar lowering, prevent arteriosclerosis, improve sanguimotor effect, cardiovascular and cerebrovascular disease is had good preventive and therapeutic effect.The present invention is pure Chinese medicinal preparation, takes rear active substance and discharges rapidly, absorbs complete, lasting medicine, can not have a rebound safe without toxic side effect after the drug withdrawal.
The specific embodiment
The invention will be further described for following specific embodiment, but not as a limitation of the invention.
Embodiment 1
1) proportioning by embodiment 1 in the following table 1 takes by weighing each raw material, and is for subsequent use;
2) Radix Aconiti Lateralis, Radix Aconiti Lateralis Preparata and Herba Asari are placed container, the decocting that adds 8 times of the weight of feeding intake boils 1h, filters, and gets filtrate for later use;
3) Radix Notoginseng and Hirudo are cleaned, oven dry grinds to form 100 order fine powders for subsequent use;
4) sulfur is ground to form 100 order fine powders for subsequent use;
5) Fructus Tribuli, Fructus Crataegi, Radix Polygoni Multiflori Preparata, Fructus Rosae Laevigatae, Herba Apocyni veneti, Semen Ziziphi Spinosae (parched), Rhizoma Acori Graminei, Rhizoma Chuanxiong, Caulis Polygoni Multiflori, Concha Ostreae, Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae, Concretio silicea Bambusae seu schizostachyi, Cortex Lycii, Radix Ilicis Pubescentis, Ramulus Cinnamomi, Rhizoma Zingiberis and Cortex Cinnamomi are cleaned be placed in the container, the decocting that adds 6 times of inventorys boils 1h, filter, obtain decoction liquor; Decoction liquor is filtered medicinal residues, get filtrate when being concentrated into 50 ℃ relative density be 1.06 extractum, add again fine powder and the step 2 of step 3) and step 4)) filtrate, mixing adds conventional excipients, drying is pulverized, and incapsulates, and makes capsule.
Embodiment 2
1) proportioning by embodiment 2 in the following table 1 takes by weighing each raw material, and is for subsequent use;
2) Radix Aconiti Lateralis, Radix Aconiti Lateralis Preparata and Herba Asari are placed container, the decocting that adds 12 times of the weight of feeding intake boils 2h, filters, and gets filtrate for later use;
3) Radix Notoginseng and Hirudo are cleaned, oven dry grinds to form 300 order fine powders for subsequent use;
4) sulfur is ground to form 300 order fine powders for subsequent use;
5) with Fructus Tribuli, Fructus Crataegi, Radix Polygoni Multiflori Preparata, Fructus Rosae Laevigatae, Herba Apocyni veneti, Semen Ziziphi Spinosae (parched), Rhizoma Acori Graminei, Rhizoma Chuanxiong, Caulis Polygoni Multiflori, Concha Ostreae, Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae, Concretio silicea Bambusae seu schizostachyi, Cortex Lycii, Radix Ilicis Pubescentis, Ramulus Cinnamomi, Rhizoma Zingiberis and Cortex Cinnamomi are cleaned and are placed in the container, decoct with water 3 times, each water that adds 20 times of raw material gross weights, each 2h that decocts, merge three times decoction liquor, filter medicinal residues, relative density was 1.14 extractum when filtrate was concentrated into 70 ℃, the fine powder and the step 2 that add again step 3) and step 4)) filtrate, mixing adds conventional excipients, granulates, drying, the granulation agent.
Embodiment 3
1) proportioning by embodiment 3 in the following table 1 takes by weighing each raw material, and is for subsequent use;
2) Radix Aconiti Lateralis, Radix Aconiti Lateralis Preparata and Herba Asari are placed container, the decocting that adds 10 times of the weight of feeding intake boils 1.5h, filters, and gets filtrate for later use;
3) Radix Notoginseng and Hirudo are cleaned, oven dry grinds to form 200 order fine powders for subsequent use;
4) sulfur is ground to form 200 order fine powders for subsequent use;
5) with Fructus Tribuli, Fructus Crataegi, Radix Polygoni Multiflori Preparata, Fructus Rosae Laevigatae, Herba Apocyni veneti, Semen Ziziphi Spinosae (parched), Rhizoma Acori Graminei, Rhizoma Chuanxiong, Caulis Polygoni Multiflori, Concha Ostreae, Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae, Concretio silicea Bambusae seu schizostachyi, Cortex Lycii, Radix Ilicis Pubescentis, Ramulus Cinnamomi, Rhizoma Zingiberis and Cortex Cinnamomi are cleaned and are placed in the container, decoct with water 2 times, the decocting that adds for the first time 15 times of raw material gross weights boils 1.5h, the decocting that adds for the second time 8 times of medical material gross weights boils 1h, merge decoction liquor twice, filter medicinal residues, relative density was 1.12 extractum when filtrate was concentrated into 60 ℃, the fine powder and the step 2 that add again step 3) and step 4)) filtrate, mixing, add conventional excipients, make ball, make pill.
Embodiment 4
1) proportioning by embodiment 4 in the following table 1 takes by weighing each raw material, and is for subsequent use;
2) Radix Aconiti Lateralis, Radix Aconiti Lateralis Preparata and Herba Asari are placed container, the decocting that adds 8 times of the weight of feeding intake boils 2h, filters, and gets filtrate for later use;
3) Radix Notoginseng and Hirudo are cleaned, oven dry grinds to form 100 order fine powders for subsequent use;
4) sulfur is ground to form 300 order fine powders for subsequent use;
5) with Fructus Tribuli, Fructus Crataegi, Radix Polygoni Multiflori Preparata, Fructus Rosae Laevigatae, Herba Apocyni veneti, Semen Ziziphi Spinosae (parched), Rhizoma Acori Graminei, Rhizoma Chuanxiong, Caulis Polygoni Multiflori, Concha Ostreae, Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae, Concretio silicea Bambusae seu schizostachyi, Cortex Lycii, Radix Ilicis Pubescentis, Ramulus Cinnamomi, Rhizoma Zingiberis and Cortex Cinnamomi are cleaned and are placed in the container, decoct with water 3 times, the decocting that adds for the first time 20 times of raw material gross weights boils 2h, the decocting that adds for the second time 10 times of raw material gross weights boils 1.5h, the decocting that adds for the third time 6 times of raw material gross weights boils 1h, merge three times decoction liquor, filter medicinal residues, relative density was 1.06 extractum when filtrate was concentrated into 70 ℃, the fine powder and the step 2 that add again step 3) and step 4)) filtrate, mixing, add conventional excipients, tabletting is made tablet.
Table 1
Raw material Embodiment 1(g) Embodiment 2(g) Embodiment 3(g) Embodiment 4(g)
Radix Aconiti Lateralis 500 1000 800 500
Fructus Tribuli 500 1000 700 1000
Radix Notoginseng 540 1000 850 540
Radix Aconiti Lateralis Preparata 100 400 250 400
Fructus Crataegi 500 1000 700 500
Radix Polygoni Multiflori Preparata 250 500 370 500
Fructus Rosae Laevigatae 250 500 390 250
Herba Apocyni veneti 250 500 400 500
Hirudo 180 360 280 180
Semen Ziziphi Spinosae (parched) 450 900 750 900
Rhizoma Acori Graminei 300 600 450 300
Rhizoma Chuanxiong 300 600 400 600
Caulis Polygoni Multiflori 900 1000 950 900
Concha Ostreae 450 900 800 900
Radix Angelicae Sinensis 300 600 500 300
Radix Salviae Miltiorrhizae 500 1000 700 1000
Concretio silicea Bambusae seu schizostachyi 250 500 400 250
Cortex Lycii 250 500 350 500
Sulfur 250 500 380 250
Radix Ilicis Pubescentis 500 1000 750 1000
Herba Asari 50 100 80 50
Ramulus Cinnamomi 100 300 200 300
Cortex Cinnamomi 100 200 160 100
Rhizoma Zingiberis 100 200 150 200
Use and the therapeutic effect of medicine of the present invention are described below in conjunction with concrete case.
Model case:
1, Xu Weizhen, the woman, 65 years old, because hypertension causes dizziness, headache, 10 years uncomfortable in chest, do not take a turn for the better through multi-treatment, and day then increase the weight of, the symptoms such as dyspnea, palpitating speed appear during walking.In March 5 in 2008 the Nikkei hospital diagnosis be 2 phases of hypertension, left side blood pressure 180/110 millimetres of mercury, right side blood pressure 170/110 millimetres of mercury.June 5 in 2008, Nikkei was taken 3 courses for the treatment of of medicine of the embodiment of the invention 1, and transference cure is followed up a case by regular visits to and had no recurrence.
2, Huang Zhiwei, the man, 54 years old, suffer from hypertension and had a surplus in 5 years, acupuncture sample pain is arranged during left breast, and with symptoms such as uncomfortable in chest, dizzy, headaches.In June 3 in 2007 the Nikkei hospital diagnosis be 2 phases of hypertension, left side blood pressure 170/110 millimetres of mercury, right side blood pressure 170/105 millimetres of mercury.Take the medicine of the embodiment of the invention 2 on August 12nd, 2007, transference cure after 2 months is followed up a case by regular visits to and is had no recurrence.
3, Li Yongfu, the man, 75 years old, on October 26th, 2010 excuse pain, dizzyly, uncomfortable in chest send the doctor medical, be diagnosed as 2 phases of hypertension and with hyperlipidemia and hypercholesterolemia, left side blood pressure 220/140 millimetres of mercury, right side blood pressure 190/130 millimetres of mercury.Take the medicine of the embodiment of the invention 3 on November 5th, 2010, transference cure after 60 days is followed up a case by regular visits to and is had no recurrence.
4, Xie Huihong, the woman, 58 years old, frequent dizziness headache over more than 10 years, the blood pressure and blood sugar Hyperlipidemia was once taken blood sugar lowering blood pressure lowering multi-medicament, poor effect.In March 3 in 2011 Nikkei hospital to detect blood pressure be 170/110 millimetres of mercury, blood-fat and blood sugar 8.0mmol/L is diagnosed as three-hypers disease, begins immediately to take the medicine that the embodiment of the invention 4 provides, symptom is eliminated after 1 month.
5, Xu Lijuan, the woman, 60 years old, suffer from dizziness headache for many years, the diseases such as cardiopalmus, insomnia, irritated irritability, soreness of the waist and knees are often accompanied in aggravation when tired or excited, once take multiple Western medicine blood pressure lowering, but easily recurrence after the drug withdrawal.In July 23 in 2010 the Nikkei hospital diagnosis be essential hypertension, blood pressure is 170/105 millimetres of mercury, and begin to take the medicine of the embodiment of the invention 1 after 2 months, dizzy, headache disappears substantially, blood pressure drops to 130~90 millimetress of mercury, continued to take medicine 1 month, transference cure is followed up a case by regular visits to and is had no recurrence.
6, high mountain peak, the man, 51 years old, be diagnosed as diabetes in 2005, fasting glucose 8.4mmol/L, 2 hours blood glucose 12.3mmol/L after the meal, facial hemiparalysis occured on the 25th in December in 2008, the right side hemiplegia, dysphonia is diagnosed as apoplexy.The medicine that on January 10th, 2009 began to take the embodiment of the invention 2 is after 3 months, and speech is clear; After continuing to take 3 months, can walk upright, still adhere at present taking, glycemic control is all right.
7, Yuan Zhijie, the man, 63 years old, have a dizzy spell, the tinnitus dim eyesight, xerostomia is the wish drink not, the tired power of body, the right side numb hand and foot, blood pressure is 22.9/13.3kPa after testing, blood viscosity is 6.3, is the apoplexy omen.Began to take the medicine 2 months of the embodiment of the invention 3 on August 15th, 2010, the thick viscosity degradation of blood, blood pressure recover normal, continue to take medicine 1 month, and the thick viscosity of blood recovers normal, follows up a case by regular visits to and has no recurrence.
8, Fan Liyun, the woman, 53 years old, existing 3 years of dizziness headache, with lumbago and skelalgia, upper and lower extremities is numb, and neck pain was gone to a doctor in December in 2007 on the 1st, detecting blood pressure is 180/110 millimetres of mercury, cholesterol 6.7mmol/L, triglyceride is 2.38mmol/L, is diagnosed as hypertension, hyperlipidemia and arteriosclerosis.On February 3rd, 2008 began to take the medicine of the embodiment of the invention 4, and after 3 months, blood pressure, blood fat all are down to normal level, followed up a case by regular visits to and had no for many years recurrence.

Claims (6)

1. medicine for the treatment of three-hypers disease, it is characterized in that: it is made by the raw material of following weight portion:
500~1000 parts of Radix Aconiti Lateralis, 500~1000 parts of Fructus Tribulis, 540~1000 parts in Radix Notoginseng, 100~400 parts of Radix Aconiti Lateralis Preparatas, 500~1000 parts of Fructus Crataegis, 250~500 parts of Radix Polygoni Multiflori Preparata, 250~500 parts of Fructus Rosae Laevigatae, 250~500 parts of Herba Apocyni venetis, 180~360 parts of Hirudos, 450~900 parts of Semen Ziziphi Spinosae (parched)s, 300~600 parts of Rhizoma Acori Graminei, 300~600 parts of Rhizoma Chuanxiongs, 900~1000 parts of Caulis Polygoni Multiflori, 450~900 parts of Concha Ostreaes, 300~600 parts of Radix Angelicae Sinensis, 500~1000 parts of Radix Salviae Miltiorrhizaes, 250~500 parts of Concretio silicea Bambusae seu schizostachyi, 250~500 parts of Cortex Lycii, 250~500 parts in sulfur, 500~1000 parts of Radix Ilicis Pubescentiss, 50~100 parts of Herba Asaris, 100~300 parts of Ramulus Cinnamomi, 100~200 parts of Cortex Cinnamomis, 100~200 parts of Rhizoma Zingiberiss.
2. the medicine for the treatment of three-hypers disease according to claim 1, it is characterized in that: the weight portion of each raw material is:
800 parts of Radix Aconiti Lateralis, 700 parts of Fructus Tribulis, 850 parts in Radix Notoginseng, 250 parts of Radix Aconiti Lateralis Preparatas, 700 parts of Fructus Crataegis, 370 parts of Radix Polygoni Multiflori Preparata, 390 parts of Fructus Rosae Laevigatae, 400 parts of Herba Apocyni venetis, 280 parts of Hirudos, 750 parts of Semen Ziziphi Spinosae (parched)s, 450 parts of Rhizoma Acori Graminei, 400 parts of Rhizoma Chuanxiongs, 950 parts of Caulis Polygoni Multiflori, 800 parts of Concha Ostreaes, 500 parts of Radix Angelicae Sinensis, 700 parts of Radix Salviae Miltiorrhizaes, 400 parts of Concretio silicea Bambusae seu schizostachyi, 350 parts of Cortex Lycii, 380 parts in sulfur, 750 parts of Radix Ilicis Pubescentiss, 80 parts of Herba Asaris, 200 parts of Ramulus Cinnamomi, 160 parts of Cortex Cinnamomis, 150 parts of Rhizoma Zingiberiss.
3. the medicine for the treatment of three-hypers disease according to claim 1, its thing is levied and is: the dosage form of described medicine is pill, granule or capsule.
4. the preparation method of the medicine for the treatment of three-hypers disease claimed in claim 1 is characterized in that: may further comprise the steps:
1) takes by weighing each raw material for standby by prescription;
2) Radix Aconiti Lateralis, Radix Aconiti Lateralis Preparata and Herba Asari are placed container, the decocting that adds 8~12 times of the weight of feeding intake boils 1~2h, filters, and gets filtrate for later use;
3) Radix Notoginseng and Hirudo are cleaned, oven dry grinds to form fine powder for subsequent use;
4) sulfur is ground to form fine powder for subsequent use;
5) with Fructus Tribuli, Fructus Crataegi, Radix Polygoni Multiflori Preparata, Fructus Rosae Laevigatae, Herba Apocyni veneti, Semen Ziziphi Spinosae (parched), Rhizoma Acori Graminei, Rhizoma Chuanxiong, Caulis Polygoni Multiflori, Concha Ostreae, Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae, Concretio silicea Bambusae seu schizostachyi, Cortex Lycii, Radix Ilicis Pubescentis, Ramulus Cinnamomi, Rhizoma Zingiberis and Cortex Cinnamomi are cleaned and are placed in the container, decoct with water 1~3 time, each water that adds 6~20 times of raw material gross weights, each 1~2h that decocts, merge decoction liquor, filter medicinal residues, relative density was 1.06~1.14 extractum when filtrate was concentrated into 50~70 ℃, the fine powder and the step 2 that add again step 3) and step 4)) filtrate, mixing is made different preparations as required.
5. the preparation method of the medicine for the treatment of three-hypers disease according to claim 4 is characterized in that: granularity 100~300 orders of the fine powder described in step 3) and the step 4).
6. the preparation method of the medicine for the treatment of three-hypers disease according to claim 4, it is characterized in that: the dosage form of described preparation is pill, granule or capsule.
CN201310016963.6A 2013-01-17 2013-01-17 Medicament for treating three-high disease (high cholesterol, high blood pressure, high blood sugar) and preparation method thereof Expired - Fee Related CN103041361B (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104352760A (en) * 2014-12-03 2015-02-18 孙孝红 Traditional Chinese medicine for treating hyperlipidemia

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1411830A (en) * 2001-10-17 2003-04-23 宋大文 Medicine for curing hypertension and its preparation method
CN101396543A (en) * 2008-10-25 2009-04-01 宁甲保 Pure traditional Chinese medicine preparation for treating cardio-cerebrovascular disease

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1411830A (en) * 2001-10-17 2003-04-23 宋大文 Medicine for curing hypertension and its preparation method
CN101396543A (en) * 2008-10-25 2009-04-01 宁甲保 Pure traditional Chinese medicine preparation for treating cardio-cerebrovascular disease

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104352760A (en) * 2014-12-03 2015-02-18 孙孝红 Traditional Chinese medicine for treating hyperlipidemia

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