CN1537619A - Traditional Chinese medicine for immunity and strengthening the body resistance - Google Patents
Traditional Chinese medicine for immunity and strengthening the body resistance Download PDFInfo
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Abstract
A Chinese medicine as an agent for strengthening immunity of humand body for treating the inflammation, tuberculosis, cancer and AIDS caused by hypoimmunity and immunodeficiency is prepared from 6 Chinese-medicinal materials including coptis root, Chinese angelica root, bupleurum root, Chuan-xiong rhizome, etc.
Description
The invention belongs to the Chinese medicine field, is the control made of one group of pure Chinese medicine because of the Chinese medicine preparation of diseases such as inflammation that hypoimmunity, immunodeficiency, the immunodeficiency of human body forms, tuberculosis, tumor, acquired immune deficiency syndrome (AIDS).
When the main cause that diseases such as the inflammation of human body, tuberculosis, tumor, acquired immune deficiency syndrome (AIDS) form is extraneous pathogenic bacteria, virus intrusion human body, because hypoimmunity, immunodeficiency, the immunodeficiency of human body cause leukocyte, lymphocyte not to play a role effectively, kill pathogenic bacteria, the virus of invasion, the human normal cell is under the effect of pathogenic bacteria, virus, form sick cell, be inflamed, diseases such as tuberculosis, tumor (cancer), acquired immune deficiency syndrome (AIDS).Now diseases such as human body inflammation, tuberculosis, tumor (cancer), acquired immune deficiency syndrome (AIDS) are generally adopted method treatments such as antibiotic, radiotherapy, chemotherapy, in the treatment disease, kill a large amount of leukocyte, lymphocyte, reduce immunity of human body itself, resistance, form former palindromia and complication easily.Do not find treatment perfect method and preparation at present as yet to lymphoid tuberculosis, tumor (cancer), acquired immune deficiency syndrome (AIDS).
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicine immunonormalizer that can effectively prevent and treat diseases such as inflammation that, immunodeficiency low because of body immunity, immunodeficiency form, tuberculosis, tumor (cancer), acquired immune deficiency syndrome (AIDS).
Solution of the present invention is based on motherland's traditional medicine to pathogenetic understanding of disease and Therapeutic Principle such as human body inflammation, tuberculosis, tumor, acquired immune deficiency syndrome (AIDS), adopt traditional secret recipe, in conjunction with the modern pharmacological research achievement, filter out the Chinese medicine preparation that forms according to the theory of Chinese medical science scientific matching, the collaborative cooperation with egg of number flavor Chinese medicine can be accelerated human stem cell, leukocyte, lymphocytic differentiation, activate the dormancy lymphocyte simultaneously, to reach curative effect.
The present invention is achieved in that
The Chinese medicine immunonormalizer is characterized in that by the component of following weight proportioning formulated: Radix Euphorbiae Pekinensis 1.5-3, Rhizoma Coptidis 1.5-3, Radix Angelicae Sinensis 3-9, Radix Bupleuri 3-9, Herba Epimedii 3-9 and Rhizoma Chuanxiong 3-9.
During use, get said medicine 200 grams, in 1: the ratio of 5-6 adds water, boils the back and adds the peeling dark egg, can take after dark egg boils.Above-mentioned dark egg also can adopt stupid egg to replace.
After the present invention adopts above-mentioned prescription, have following clinical effectiveness:
1, effective diseases such as the inflammation that forms because of HIV, immunodeficiency of control, tuberculosis, tumor, total effective rate 98%; To infective inflammation, lymphoid tuberculosis cure rate 95%, to tumor (cancer) suppression ratio 87%, to acquired immune deficiency syndrome (AIDS) remission rate 95%, suppression ratio 90%.
2, can obviously increase lymphocyte quantity.
3, the obvious dissipation pathogenic bacteria of energy, virus.
4, pure Chinese medicinal preparation, taking convenience, toxic and side effects is little.
5, the recovery that the lymphocyte after radiotherapy, the chemotherapy is reduced has fabulous effect.
Disease preventing and treating principle of the present invention:
The present invention is according to human immunology's principle, utilizes some flavor Chinese medicines, makes through specific technology.The present invention is a Chinese traditional compound medicine, and wherein the Radix Euphorbiae Pekinensis has to relieve oedema or abdominal distension through diuresis or purgation to remove expires, and the merit of dispersing swelling and dissipating binds is usually used in treating carbuncle sore tumefacting virus, scrofula sucutaneous nodule, acute and chronic edema and hepatitis interstitialis chronica ascites etc.; Rhizoma Coptidis, Radix Bupleuri are heat and toxic materials clearing away medicine, have very wide antibacterial range, and have and strengthen leukocytic phagocytic activity, and effects such as blood pressure lowering, function of gallbladder promoting, analgesic, calm, analgesia, anticancer, radioprotective are arranged again; Radix Angelicae Sinensis, Herba Epimedii are immune mediator agent and immune enriching substance; Rhizoma Chuanxiong is a blood-activating formula, above medicine is fried in shallow oil together with the peeling dark egg, make the dark egg composition that absorbs the drug, dark egg rich in proteins, several amino acids, vitamin and other trace element have more nutrition and improve human body immunity's effect than other common eggs.After taking this preparation, medicine can directly affact bone marrow, the thymus of human body, accelerate human stem cell, leukocyte, lymphocytic differentiation, generation, maturation, has the lymphocytic effect of the dormancy of activation simultaneously, kill invasion pathogenic bacteria, virus, reach the purpose of control because of diseases such as the inflammation that body immunity is low, immunodeficiency, immunodeficiency form, tuberculosis, tumor (cancer), acquired immune deficiency syndrome (AIDS); This product can effectively be treated the lymphoid tissue disease, can effectively improve human body periphery lymphsystem, promotes lymph fluid circulation.
The present invention is made by pure Chinese medicine, and modern pharmacological research proves:
The Radix Euphorbiae Pekinensis: relieving oedema or abdominal distension through diuresis or purgation, it is full to remove, dispersing swelling and dissipating binds.Be used for breast abdomen hydrops, difficulty in urination and defecation, carbuncle sore tumefacting virus, scrofula sucutaneous nodule, phlegm retention are gathered, epilepsy is gone mad, acute and chronic edema and hepatitis interstitialis chronica ascites etc.Zoopery shows that rat experiment ascites is had obvious diuresis.Knoxia valerianoides is to various dysentery bacillus, and Diplococcus pneumoniae and Hemolytic streptococcus have inhibitory action.
Rhizoma Coptidis: heat clearing and damp drying, eliminating fire and detoxication.Very wide antibacterial range is arranged, dysentery bacterium, Bacillus typhi, bacillus pyocyaneus, escherichia coli, diphtheria corynebacterium, bordetella pertussis, tubercule bacillus, staphylococcus, meningococcus, Hemolytic streptococcus, Diplococcus pneumoniae etc. are all had than significant inhibitory effect; To leptospira, ameba, infusorian, influenza virus and multiple pathogenic dermatophytes, inhibitory action is arranged also.Wherein the inhibitory action to dysentery bacterium is the strongest.And can strengthen leukocytic phagocytic activity, effects such as blood pressure lowering, function of gallbladder promoting, analgesic, calm, analgesia, anticancer, radioprotective are arranged again.
Radix Angelicae Sinensis: replenishing blood for nourishing heart, promoting blood flow to regulate menstruation is the key medicine of enriching blood.With the shallow complexion of controlling blood deficiency, feel dizzy, disease such as cardiopalmus is weak.This product was both enriched blood, and hot again loosing invigorated blood circulation, the energy cold expelling of holding concurrently, and the effect of existing menstruction regulating and pain relieving has the blood deficiency of elimination, blood stasis, the pain caused merit of cold in blood again.Radix Angelicae Sinensis polysaccharide be significantly increased mice E-garland formation rate and the effect of lipase stained positive rate, the prompting Radix Angelicae Sinensis polysaccharide is effective cellular immunization promoter.
Radix Bupleuri: evacuate and bring down a fever soothing liver-QI, yang invigorating.Have effects such as analgesic, analgesia, calmness, convulsion, antidepressant, antiinflammatory.To Immune Effects: ip in mice Radix Bupleuri polysaccharide (molecular weight 9900) can significantly increase the spleen coefficient, and peritoneal macrophage is engulfed antibody titer in percent and phagocytic index and the influenza virus serum, but does not influence splenocyte secretion hemolysin.The Radix Bupleuri polysaccharide obviously improves the activity of activatory splenocyte conversion ratio of Con A and natural killer cell, shows that the Radix Bupleuri polysaccharide can improve mice body fluid and cellular immune function, and makes immunosuppressive condition that to a certain degree recovery be arranged.In addition, Radix Bupleuri also has antitussive, antioxidation, antipathogen, antitumor and antimutagenic effect.
Herba Epimedii: the kidney invigorating Xing Yang, expelling wind and removing dampness, the hard muscle of strong will.Adopt the injection antilymphocyte serum to cause mouse immune to hang down drag, and treat, to understand the mechanism of Herba Epimedii immune stimulatory with Herba Epimedii.Detect through immunologic function: hemolytic plaque test is the result prove: the ability that Herba Epimedii can make the mononuclear phagocyte of immunologic hypofunction mouse spleen lymphocyte quantity, PFC reaction and mice engulf carbon granule returns to normal level.Herba Epimedii also has blood pressure lowering, blood sugar lowering, blood fat reducing, antitussive, eliminates the phlegm, relievings asthma, the effect of antiinflammatory, defying age, antitumor and resisting pathogenic microbes.
Rhizoma Chuanxiong: blood-activating and qi-promoting, wind-expelling pain-stopping.The hot temperature of loosing of this product is logical, the whole body of can leading to, but both blood circulation promoting and blood stasis dispelling again can activating QI to alleviate the depression and pain relieving with regulating menstruation, effect with sensible QI and blood is usually used in treating all pains of stagnation of blood stasis or qi depression to blood stasis, sore, carbuncle and painful swelling, headache, arthralgia pain, angina pectoris, trigeminal neuralgia etc.Simultaneously, Rhizoma Chuanxiong can reduce the surface of tumor cells activity, makes it be difficult for sticking agglomerating and is easy to single killing in blood flow.The thrombus dissolving effect of Rhizoma Chuanxiong can change cancer patient's blood flow circulation " hypercoagulability ", makes cancerous cell be difficult for adhesion stop, implantation in blood flow, also is easy to be killed.Rhizoma Chuanxiong can also microcirculation improvement, increases the blood oxygen supply of radiation injury position, and it is synthetic to suppress collagen, alleviates radioactivity pathology and changes, and helps chemotherapeutics and arrives disease institute, kills cancerous cell.Experiment in vitro shows: Rhizoma Chuanxiong has obvious inhibitory action to multiple gram negative bacteria such as large intestine, dysentery, distortion, green pus, typhoid fever, Salmonella paratyphi and comma bacilluses, and some pathogenic dermatophytes is also had the effect of pressing down system.It more than is the pharmacology of the used main medicine of the present invention.
Radix Ginseng: strongly invigorating primordial QI, invigorating the spleen to benefit the lung, promoting the production of body fluid to quench thirst, the Fructus Alpiniae Oxyphyllae of calming the nerves.Diseases such as the deficiency of vital energy is desired to take off with controlling, deficiency of spleen-QI, lung qi lose void, deficiency of both the heart and spleen, blood deficiency and yellow complexion, Tianjin wound are thirsty.Radix Ginseng is to neural influence: according to the electroencephalogram of animal and the research of trained reflex method, Radix Ginseng mainly is to strengthen corticocerebral process of excitation, also can strengthen process of inhibition simultaneously, improves the motility of neural activity process.It can also improve people's the general mentality and the function of muscle power, and enhancing body is to the defence capability of various destructive stimuluses.Animal is at massive blood loss or suffocate and when being in critically ill state, inject gen-seng immediately, can make to reduce to very low-level blood pressure and firmly go up, and prolongs the time-to-live of animal, and even promotes that animal gets well.Radix Ginseng has the resistance effect, and DNA variation is the root of disease, aging and canceration, also is pathological information, is in " it is sick to dive " state at human body and during no conscious sympton, corrects with antimutagen, can be with disease eradication in bud; Radix Ginseng to the DNA rat liver cancer development takes place there is significant inhibitory effect; Use the ginsenoside and can cause adrenal cortex ketone secretion increase by the exogenous ACTH of partial offset, promote NK cell and T cytoactive to recover.The prompting ginsenoside can participate in the adjusting of body's immunity by the activity of adjusting hypophysis (ACTH)-adrenal gland's (corticosterone) axle.
Rhizoma Polygonati Odorati: nourishing YIN and moistening the lung, reinforcing stomach reg fluid, relieving restlessness heart tonifying.Be used for diseases such as calentura dryness of the mouth and throat, the few expectorant of dry cough, vexed cardiopalmus, diabetes.Irritate stomach with the Rhizoma Polygonati Odorati alcohol extract, can obviously improve the huge cytophilic phagocytic function of mouse peritoneal, improve the breeder reaction of spleen pouring, illustrate that Rhizoma Polygonati Odorati is a kind of to strengthen the immunostimulant of humoral immunization and phagocytic function ConA.The immunity of Rhizoma Polygonati Odorati and body and hemopoietic are regulated.It is a kind of to strengthen the immunostimulant of humoral immunization and cytophagy that steroidal in the Rhizoma Polygonati Odorati presses down the glycoside composition.
Radix Rehmanniae Preparata: the YIN nourishing of enriching blood, beneficial essence is filled out marrow, strong waist kidney tonifying.Be used for the hepatic and renal YIN deficiency, soreness of the waist and knees, osteopyrexia and fever, interior-heat is quenched one's thirst, blood deficiency and yellow complexion, severe palpitation, menoxenia, bleeding not during menses, dizzy, tinnitus, diseases such as early whitening of beard and hair.Radix Rehmanniae Preparata also has effects such as heart tonifying, diuresis, blood pressure lowering, blood sugar lowering, defying age, antithyroid superfunction.
Above-mentioned Radix Ginseng, Rhizoma Polygonati Odorati, Radix Rehmanniae Preparata three medicines are made antimutagen, immunomodulator and nourishing agent in the present invention.Auxiliary agent as treatment inflammation, tuberculosis, tumor, acquired immune deficiency syndrome (AIDS).
Herba Houttuyniae: heat-clearing and toxic substances removing, eliminating carbuncle evacuation of pus, relieving stranguria by diuresis.Be used for diseases such as lung abscess, cough due to lung-heat, pathopyretic ulcer, damp and hot stranguria, damp-heat dysentery.Houttuynine sodium bisulfite all has inhibitory action in various degree to staphylococcus aureus, Diplococcus pneumoniae, alpha streptococcus, hemophilus influenza, micrococcus catarrhalis, Bacillus typhi and tubercule bacillus etc.Can strengthen phagocytic activity of leukocytes.The Herba Houttuyniae decoct is engulfed the ability of staphylococcus aureus in the external human peripheral leucocytes that can significantly promote.Neo-houttuyninum and class houttuynine sodium bisulfite (acetyl acetaldehyde) im all can obviously improve the phagocytic activity of Turnover of Mouse Peritoneal Macrophages to chicken red blood cell, and promotes the generation of hemolytic antibody due to the SRBC immunity, antagonism caused by cyclophosphamide leukopenia.Herba Houttuyniae can also the enhancing body nonspecific immunity and the ability of specific immunity.In addition, Herba Houttuyniae also has analgesia, hemostasis, antitussive and antiasthmatic, antiallergic, antiinflammatory, antibiotic, antiviral, antitumor action.
Herba Taraxaci: heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, inducing diuresis for treating stranguria syndrome.Be used to treat pyogenic infections from tumour or sore, acute mastitis, scrofula, conjunctival congestion, pharyngalgia, lung abscess, acute appendicitis, jaundice due to damp-heat, the puckery pain of pyretic stranguria.This product decoct can significantly improve human peripheral blood lymphocytes blast cell occasionality conversion ratio external.Herba Taraxaci has stronger killing action to staphylococcus aureus, Hemolytic streptococcus; Diplococcus pneumoniae, meningococcus, diphtheria corynebacterium, bacillus pyocyaneus, Bacillus proteus, dysentery bacterium, Bacillus typhi and micrococcus catarrhalis etc. there is certain killing action; Some virus, fungus and leptospira also there is inhibitory action.In addition, still have function of gallbladder promoting, diuresis, be good for the stomach, effect such as antitumor, antiendotoxin.
Above-mentioned Herba Houttuyniae, Herba Taraxaci two medicines, the ancillary drug of do treatment in the present invention pneumonia, idiopathic interstitial pneumonia and lung tumor.
The Pseudobulbus Bletillae (Rhizoma Bletillae): astringing to arrest bleeding, detumescence and promoting granulation.Be used for hemoptysis and spit blood traumatic hemorrhage, sore swollen toxin, chapped skin, diseases such as pulmonary tuberculosis hemoptysis, ulcer haemorrhage.
Rhizoma Cyperi: promoting QI circulation for relieving depression, menstruction regulating and pain relieving.Be used for stagnation of QI due to depression of the liver, breast, rib, abdominal distention, dyspepsia, breast gastral cavity spleen is vexed, diseases such as colic of cold type stomachache.
Fructus Aurantii Immaturus: dispelling the stagnated QI removing food stagnancy, the diffusing painful abdominal mass of reducing phlegm.Be used for long-pending full distending pain, heavy behind the dysentery, the expectorant vapour lock thoracic obstruction that stagnates, diseases such as blocked-up chest.
The above-mentioned Pseudobulbus Bletillae (Rhizoma Bletillae), Rhizoma Cyperi, Fructus Aurantii Immaturus three flavors are in the present invention as the auxiliary agent for the treatment of gastritis, gastric and duodenal ulcers and gastric cancer.
Herba Abri: heat-clearing and toxic substances removing, Shugan Zhitong.Be used for jaundice due to damp-heat, side of body rib does not relax gastral cavilty distending pain, acute and chronic hepatitis, diseases such as mastitis.
Herba Artemisiae Scopariae: clearing away damp-heat, jaundice eliminating subcutaneous ulcer.Be used for the jaundice oliguria, the eczema pruritus; Diseases such as infectious jaundice hepatitis.That Herba Artemisiae Scopariae has is analgesic, analgesia, antiinflammatory, blood fat reducing, blood sugar lowering, blood pressure lowering, protect the liver, function of gallbladder promoting, antibiotic, antiviral, anti-leptospira, effect such as anticancer.Herba Artemisiae Scopariae has and promotes the leukocyte division, and the leukocyte increasing number improves the immunocompetence of T cell, participates in effects such as the immunomodulating of body and inducement interferon, thereby improves the immunologic function of human body from many aspects.
Fructus Gardeniae: pathogenic fire purging relieving restlessness, clearing away heat and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body.It is vexed to be used for calentura, the jaundice dark coloured urine, and blood strangury and dry pain, heat in blood is told nosebleed, conjunctival congestion and swelling pain, diseases such as pathogenic fire,toxin and furuncles.In addition, Fructus Gardeniae also has calm, hypnosis; Analgesia, cooling; Antiinflammatory, protect the liver; Promote effects such as bile, gastric juice, pancreatic secretion.
Above-mentioned Herba Abri, Herba Artemisiae Scopariae, Fructus Gardeniae three medicines are in the present invention as the ancillary drug for the treatment of hepatitis, liver tumor.
Radix Trichosanthis: clearing away heat and promoting production of body fluid, detumescence and apocenosis.Be used for the calentura excessive thirst, lung-heat type cough, interior-heat is quenched one's thirst, diseases such as sore swollen toxin.Trichosanthin has immunogenicity to human body, trichosanthin drug induced abortion person and the ectopic pregnancy, the hydatidiform mole patient that treat through trichosanthin, the intramuscular injection crystal trichosanthin can stimulate body to produce the specific IgE antibody and the IgG antibody formation reaction of varying degree.Trichosanthin also is a kind of immunosuppressant simultaneously, and pair cell immunity and humoral immunization all have inhibitory action.Radix Trichosanthis also has the effect of antiinflammatory, antitumor, anti-AIDS.
The present invention adopts the ancillary drug of Radix Trichosanthis as treatment mastitis, breast tumor, lump, breast carcinoma and acquired immune deficiency syndrome (AIDS).
In sum, the present invention is according to human immunology's principle, utilizes cooperating of Chinese medicine and egg, and medicine is immersed in the egg.Medicine directly affacts bone marrow, the thymus of human body, accelerate human stem cell, leukocyte, lymphocytic differentiation, generation, maturation, activate the dormancy lymphocyte simultaneously, kill invasion pathogenic bacteria, virus, reach the purpose of control because of diseases such as the inflammation that body immunity is low, immunodeficiency, immunodeficiency form, tuberculosis, tumor (cancer), acquired immune deficiency syndrome (AIDS).
The specific embodiment
Below in conjunction with embodiment the present invention is elaborated.
Embodiment 1.Choose the Radix Euphorbiae Pekinensis 20 gram, Rhizoma Coptidis 20 grams, Radix Angelicae Sinensis 60 grams, Radix Bupleuri 60 grams, Herba Epimedii 60 grams and Rhizoma Chuanxiong 60 grams respectively, clean impurity is removed in screening meticulously, and it is standby to mix the back.Get said medicine 200 grams, in 1: the ratio of 5-6 adds water, boils the back and adds the peeling egg, promptly makes medicine of the present invention after egg boils.Instructions of taking: sooner or later respectively obey one piece, 7-10 day is a course of treatment.
Embodiment 2.Choose the Radix Euphorbiae Pekinensis 20 grams, Rhizoma Coptidis 20 grams, Radix Angelicae Sinensis 60 grams, Radix Bupleuri 60 grams, Herba Epimedii 60 grams, Rhizoma Chuanxiong 60 grams, Radix Ginseng 15 grams, Rhizoma Polygonati Odorati 10 grams, Radix Rehmanniae Preparata 20 grams, Herba Houttuyniae 20 grams, Herba Taraxaci 20 grams, the Pseudobulbus Bletillae (Rhizoma Bletillae) 10 grams, Rhizoma Cyperi 6 grams, Fructus Aurantii Immaturus 8 grams, Herba Abri 20 grams, Herba Artemisiae Scopariae 10 grams, Fructus Gardeniae 8 grams, Radix Trichosanthis 10 grams respectively.Clean impurity is removed in screening meticulously, and is standby after mixing.The above-mentioned Radix Euphorbiae Pekinensis can use Rhizoma Paridis, Flos Genkwa, Radix Kansui, Semen Pharbitidis or Herba euphorbiae lunulatae to substitute, but consumption must prudent allotment.Get said medicine 200 grams, in 1: the ratio of 5-6 adds water, boils the back and adds the peeling dark egg, promptly makes medicine of the present invention after egg boils.Instructions of taking: sooner or later respectively obey one piece, 7-10 day is a course of treatment.
For verifying therapeutic effect of the present invention, the present invention has carried out following clinical trial in 1998 to 2003 in Donga, Shandong Province county Sixth Man people hospital:
1. to the therapeutic test of inflammation:
1.1 clinical data: test various inflammation 145 examples altogether, gender-disaggregated: male 68 examples, women 77 examples; Age 6-75 year.All case all meets the diagnostic criteria of inflammation through clinical and experimental check.Wherein: enteritis 15 examples, gastritis 10 examples, pneumonia 16 examples, hepatitis 12 examples, pleuritis 6 examples, pancreatitis 10 examples, mastitis 10 examples, nephritis 10 examples, pharyngitis 8 examples, esophagitis 10 examples, parotitis 12 examples, tonsillitis 14 examples, lymphadenitis 12 examples.Enteritis is got 10 examples, and other inflammation are got half, uses this therapy to treat, and is the treatment group; Other enteritis 5 examples, other inflammation halves are matched group.Two groups of patients' clinical manifestation and lab testing result are complementary, and have comparability preferably.
1.2 method and result:
Two groups of patients are after coming institute, and the treatment group is taken the medicine egg of this law processing, sooner or later respectively obey one piece, and in conjunction with state of an illness determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs, other decoction that takes traditional Chinese medicine; Take 3 days state of an illness and alleviate, 7-10 day all cures, and the back of leaving hospital is followed the tracks of patient and investigated 60, does not have recurrence and complication.Matched group adopts antibiotic therapy, and the state of an illness alleviated in 7 days, 10-15 day cure rate 95%, and the back of leaving hospital is followed the tracks of patient and is investigated 60, and recurrence or complication person account for 40%.
1.3 curative effect judging standard: produce effects: cure or basic the healing, treatment back leukocyte, neutrophilic granulocyte recover normal; Effectively: subjective symptoms alleviates or the outward appearance sign is improved; Leukocyte, neutrophilic granulocyte number are tending towards normal; Invalid: subjective symptoms does not alleviate or the outward appearance sign is not improved; Leukocyte, neutrophilic granulocyte number do not change.
Observation of curative effect: 75 routine inflammatory patients are organized in treatment, and obvious effective rate 91%, effective percentage 9% are observed in the treatment back.In the treatment group, take Chinese medicine preparation of the present invention, 1-36h eliminate pain person accounts for former inflammation part on the 83%, 3 and swells and ache to eliminate and account for 90%, and 1-4 week leukocyte, neutrophilic granulocyte recover to account for 92% normally; Matched group accounts for 74%, and treatment group effective percentage is 100%, this shows, the treatment group is better than matched group.Efficacy result sees the following form:
Curative effect data synopsis
| Total treatment number (example) | Produce effects number (example) | Significant figure (example) | Invalid number (example) | |
| The treatment group | ????75 | ????68 | ????7 | |
| Matched group | ????70 | ????35 | ????17 | ????18 |
| Content | Before the treatment | After the treatment | ||||||||||
| Total white blood cells | The neutrophilic granulocyte accounting | Total white blood cells | The neutrophilic granulocyte accounting | |||||||||
| More than 10000 | 10000 - 4000 | Below 400 0 | More than 70% | 50- 70％ | Below 50% | More than 10000 | 10000 -4000 | Below 4000 | More than 70% | 50- 70％ | Below 50 % | |
| Treatment group (example) | 40 | ?20 | ?15 | ?40 | ?20 | ?15 | ?6 | ??69 | ?0 | ?6 | ?69 | ?0 |
| Matched group (example) | 35 | ?21 | ?14 | ?35 | ?21 | ?14 | ?10 | ??52 | ?8 | ?10 | ?52 | ?8 |
(normal range: leukocyte 4000-10000, neutrophilic granulocyte accounting 50-70%)
2. to scrofulous therapeutic test:
2.1 clinical data: test lymphoid tuberculosis disease 60 examples altogether, gender-disaggregated: male 28 examples, women 32 examples; Age 7-41 year.All case all meets the diagnostic criteria of lymphoid tuberculosis disease through clinical and experimental check.Wherein get half, use this therapy to treat, be the treatment group; Other halves, use antibiotic etc. is treated, and is matched group.Two groups of patients' clinical manifestation and lab testing result are complementary, and have comparability preferably.
2.2 method and result: two groups of patients are after coming institute, and the treatment group adopts the medicine egg of this law processing, sooner or later respectively obey one piece, take 7 days state of an illness and alleviate, and 10-45 days 28 example recovery from illness, 2 examples are almost recovered, and the back of leaving hospital is followed the tracks of patient and is investigated 180, does not have recurrence and complication.Matched group adopts method treatments such as antibiotic, treat 7 days state of an illness to alleviate, and 10-50 days 29 example recovery from illness, 1 example is invalid, and the back tracking patient that leaves hospital investigates 180, recurs or has complication person to account for 48%.
2.3 curative effect judging standard: cure: the lymphoid tuberculosis enlargement is eliminated, the face that festers healing, and it is normal that the hemogram index is recovered, and it is normal that the outward appearance sign is recovered, no longer recurrence; Effectively: pleiades dwindle or the face that festers is restrained, and it is normal that the hemogram index is tending towards; Invalid: pleiades do not dwindle or the face that festers is not restrained healing, and the hemogram index does not become.Efficacy result sees the following form:
Curative effect data synopsis:
| Total treatment number | The produce effects number | Significant figure | Invalid number | |
| Treatment group (example) | ????30 | ????28 | ????2 | |
| Matched group (example) | ????30 | ????23 | ????6 | ????1 |
| Content | Before the treatment | After the treatment | ||||||||||
| Leukocyte count | The lymphocyte accounting | Leukocyte count | The lymphocyte accounting | |||||||||
| More than 10000 | 10000 -4000 | Below 4000 | More than 40% | ?20- ?40％ | Below 20% | More than 10000 | 10000 -4000 | Below 4000 | More than 40% | ?20- ?40％ | Below 20% | |
| Treatment group (example) | 30 | ?20 | ?10 | ?30 | ?30 | |||||||
| Matched group (example) | 30 | ?18 | ?12 | ?30 | ?11 | ?19 | ||||||
3. to tumor, treatment for cancer test:
3.1 clinical data: test various tumors (cancer) 62 examples altogether, gender-disaggregated: male 32 examples, women 30 examples; Age 14-82 year.Wherein: lymphatic cancer 12 examples, pulmonary carcinoma 14 examples, hepatocarcinoma 10 examples, gastric cancer 8 examples, esophageal carcinoma 6 examples, cancer of pancreas 6 examples, breast carcinoma 6 examples.All case all meets the diagnostic criteria of cancer through clinical and experimental check.Be that other hospital treatments are invalid to change the treatment of my institute over to, do not adopt the contrast experiment.
3.2 method and result: patient all takes the medicine egg of this law processing after coming institute, sooner or later respectively obey one piece, and in conjunction with state of an illness determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs, other decoction that takes traditional Chinese medicine is taken 7 days state of an illness and is alleviated, 10-30 day lesion volume reduces, and the back of leaving hospital is followed the tracks of patient and investigated 1 year, does not have recurrence and complication.
3.3 curative effect judging standard:
Produce effects: tumor focus dwindles gradually, and pain disappears, and outward appearance body constitution gradually recovers one's health, and obviously prolong life cycle.
Effectively: growth of tumor is in that to take medicine egg 1-2 of the present invention controlled after week, and subjective symptoms alleviates, the lesions position pain relief.
Efficacy result sees the following form:
| Total treatment number | The produce effects number | Significant figure | Invalid number | |
| Treatment group (example) | ????62 | ????36 | ????26 |
4. to the therapeutic test of acquired immune deficiency syndrome (AIDS) and complication:
4.1 clinical data: altogether in the Henan Province county (according to the experimenter require underground) experiment acquired immune deficiency syndrome (AIDS) 30 examples, gender-disaggregated: male 11 examples, women 19 examples; Age 9-52 year.Wherein: CD4+ is person's 22 examples between 200-400/ul, and CD4+ is lower than 200/ul person's 8 examples.
HIV sufferers is local county epidemic prevention station and makes a definite diagnosis the AIDS one-tenth positive, and has complication to occur, and does not adopt the contrast experiment; All take the egg of this law processing, sooner or later respectively obey one piece, and in conjunction with determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs and the state of an illness decoction that takes traditional Chinese medicine in addition, take 14 days state of an illness and alleviate, original fever on the 30th, headache, weak, erythema (festering) disappear, with the pneumonia healing, pulmonary tuberculosis healing or improvement, the lymphoid tuberculosis recovery from illness; CD4+, cd8 cell counting near or reach healthy people's standard (500-1500/ul).
4.2 method and result:
Patient adopts the egg of this law processing in receiving treatment, sooner or later respectively obey one piece, takes 15 days state of an illness and alleviates, transference cure on the 30th, no complication.
4.3 curative effect judging standard:
Produce effects: original fever, headache, weak, erythema transference cures such as (festering), CD4+, cd8 cell number reach or near healthy people's standard (500-1500/ul).
Effectively: original fever, headache, weak, erythema sxs such as (festering), with pneumonia healing, pulmonary tuberculosis healing or take a turn for the better the lymphoid tuberculosis recovery from illness; CD4+, the approaching healthy people's of cd8 cell counting standard (500/ul).
Efficacy result sees the following form:
| Total treatment number | The produce effects number | Significant figure | Invalid number | |
| Treatment group (example) | ????30 | ????22 | ????8 |
Curative effect data synopsis:
| Content | Before the treatment | After the treatment | ||||
| The CD4+ cell | The CD4+ cell | |||||
| More than 800 | ?400-800 | Below 400 | More than 800 | ??500-800 | Below 500 | |
| Treatment group (example) | ????1 | ????9 | ????20 | ????12 | ????16 | ????2 |
5. to people living with AIDS's therapeutic test:
5.1 clinical data:
In Henan Province county experiment AIDS virus carrier 40 examples, gender-disaggregated: male 22 examples, women 18 examples altogether; Age 12-49 year.
The AIDS virus carrier is local county epidemic prevention station and makes a definite diagnosis the AIDS one-tenth positive, does not still have complication and occurs; Adopt contrast experiment, 20 examples to take the egg of this law processing, sooner or later respectively obey one piece, and in conjunction with determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs and the state of an illness decoction that takes traditional Chinese medicine in addition; All the other 20 examples are not taken any medicine.
5.2 method and result:
Patient adopts the egg of this law processing in receiving treatment, sooner or later respectively obey one piece, takes 30.After taking 30 days, CD4+ cell number average has rising in various degree; Took experiment periods 2 years after 6 months again 30 days.Take none example generation complication of experimenter in back 2 years.The pill taker person of developing complications 12 examples do not account for 60%.
5.3 curative effect judging standard:
Effectively: the CD4+ cell counting is near healthy people's standard (500/ul).No complication occurs.Efficacy result sees the following form:
Curative effect data synopsis:
| Total treatment number | The produce effects number | Significant figure | Invalid number | |
| Treatment group (example) | ????20 | ????12 | ????8 | |
| Matched group (example) | ????20 | ????2 | ????10 | ????8 |
| Curative effect | Before the treatment | After the treatment | ||||
| The CD4+ cell | The CD4+ cell | |||||
| More than 800 | ?400-800 | Below 400 | More than 800 | ?400-800 | Below 400 | |
| Treatment group (example) | ????1 | ???14 | ????5 | ????8 | ????12 | |
| Matched group (example) | ????2 | ???16 | ????2 | ????2 | ????10 | ????8 |
Originally experimental results show that:
Diseases such as the inflammation that the present invention can effectively prevent and treat is low because of body immunity, immunodeficiency, immunodeficiency form, tuberculosis, tumor, acquired immune deficiency syndrome (AIDS).
Be the concrete case of utilizing this method treatment disease below:
Example 1, pay * *, the woman, 40 years old, in February, 1998, conscious liver discomfort with paroxysmal pain, was satisfied the diagnosis to the People's Hospital, Liaocheng Prefecture, hepatic region CT scan (unenhanced add reinforcement): the big I of liver form, the right lobe of liver back segment is seen multiple strip low-density shade, and CT value 37-48Hu does not have obvious occupy-place; Enhanced ct scans, focus is obviously strengthened, and most of low-density kitchen range disappears, and extrahepatic duct does not have expansion, hepatic portal clear in structure, gallbladder Non Apparent Abnormality.Splenomegaly, density is even.Diagnostic result: 1, occupying lesion of right lobe.Consider: (1) hepatocarcinoma (2) hepatic haemangioma; 2, splenomegaly.Begin to take preparation of the present invention in March, 1998, take a week after, conscious pain relief is obeyed a week again, pain is lighter, and sleep also has improvement, and CT examination finds that focus is reduced into 4.8 * 5.6cm by 7.6 * 8.3, and another subsequently serveing on used for 15 weeks, focus all disappears, and follows up a case by regular visits to complete recovery of health 8 years.
Example 2, king * *, the woman, 45 years old, spring in 1999 was suffered from idiopathic interstitial pneumonia (pulmonary fibrosis pathological changes, PCP pneumonia), and through seeing the doctor for treatment in many ways, the state of an illness is not felt any better, up to winter then, patient respiratory is difficulty further, and constantly hemoptysis is coughed pus, and can not fall asleep night, the patient is through reaching decocting of disease more than a year, health is very weak, and thin is skinny, and body weight has only 35 kilograms, life is on the point of dying, have to rely on input oxygen to earn a bare living, family numbers of patients is its more than 70,000 yuan of cost of seeing the doctor for treatment, only oxygen take just reach 10,000 surplus yuan.In December, 1999, the patient begins to take preparation of the present invention, only takes three days, patient's oxygen of just trying to remove is removed the oxygen time for the first time and is reached 1.5h, and removed the oxygen time in later several days all has prolongation at every turn, take after week and removed oxygen fully, the patient took for 26 weeks continuously, and health is returned to one's perfect health.Have rosy cheeks and glossy weight recovery to 70 kilogram.With anti-5 years, keep fit, not recurrence more always.
Example 3, Lee * *, the man 19 years old, suffers from hepatitis in June, 2003.HBV-DNA is qualitative: the positive; HBV-DNA is quantitative: 7.46 * 10
7Copy/ml; Five index of hepatitis b testing result: the HBsAg positive; Anti--the HBs feminine gender; The HBeAg positive; Anti--the HBe feminine gender; Anti--the HBc positive.Patient's sign, skin and eyes all turn to be yellow, and health is become thin.The conscious general weakness of patient.On July 8th, 2003 began to take preparation of the present invention, and around taking continuously, patient's sign has change greatly, and it is normal that skin and eye color recover, and weak phenomenon is eliminated.On August 6th, 2003 was detected, and HBV-DNA is quantitative: 1.85 * 10
7Copy/ml reduces by 5.61 * 10 before taking preparation of the present invention
7Copy/ml.
Example 4, poplar *, man, 24 years old; Occurred that fester in fever, headache, weak, whole body skin table erythema, oral cavity, the lymph nodes of body as a whole enlargement in 2002, epidemic prevention station is diagnosed as acquired immune deficiency syndrome (AIDS) through local county.Take preparation of the present invention in May, 2003, and take traditional Chinese medicine in addition decoction Radix Ginseng, Radix Notoginseng, Poria etc., fevers, headache after 2 weeks, weak, erythema, fester, sx such as lymph nodes of body as a whole enlargement; Continue to take said preparation; After 30 days, fever, headache, weak, erythema, fester, transference cure such as lymph nodes of body as a whole enlargement; 45 days after the absolute numeration of peripheral blood detection lymph CD4+ cell reaches 800ul (healthy people's standard 500-1500/ul).Do not develop complications, do not recur.
Claims (5)
1, Chinese medicine immunonormalizer is characterized in that it being that component by the following weight proportioning is formulated: Radix Euphorbiae Pekinensis 1.5-3, Rhizoma Coptidis 1.5-3, Radix Angelicae Sinensis 3-9, Radix Bupleuri 3-9, Herba Epimedii 3-9 and Rhizoma Chuanxiong 3-9.
2, Chinese medicine immunonormalizer according to claim 1 is characterized in that the weight proportion of above-mentioned component is: the Radix Euphorbiae Pekinensis 2, Rhizoma Coptidis 2, Radix Angelicae Sinensis 6, Radix Bupleuri 6, Herba Epimedii 6 and Rhizoma Chuanxiong 6.
3, Chinese medicine immunonormalizer according to claim 1 and 2 is characterized in that above-mentioned component also comprises: Radix Ginseng 5-15, Rhizoma Polygonati Odorati 5-15, Radix Rehmanniae Preparata 10-30, Herba Houttuyniae 10-30, Herba Taraxaci 10-30, Pseudobulbus Bletillae (Rhizoma Bletillae) 6-12, Rhizoma Cyperi 3-9, Fructus Aurantii Immaturus 6-9, Herba Abri 15-30, Herba Artemisiae Scopariae 6-12, Fructus Gardeniae 6-9, Radix Trichosanthis 10-15.
4, Chinese medicine immunonormalizer according to claim 3 is characterized in that: the above-mentioned Radix Euphorbiae Pekinensis can use Rhizoma Paridis, Flos Genkwa, Radix Kansui, Semen Pharbitidis, Herba euphorbiae lunulatae to substitute.
5, Chinese medicine immunonormalizer according to claim 4 is characterized in that: get said medicine, in 1: the ratio of 5-6 adds water, boils the back and adds the peeling egg, gets final product after egg boils.
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| Application Number | Priority Date | Filing Date | Title |
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| CNA2003101054439A CN1537619A (en) | 2003-10-24 | 2003-10-24 | Traditional Chinese medicine for immunity and strengthening the body resistance |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103330901A (en) * | 2013-05-29 | 2013-10-02 | 陈松 | Chinese medicine for curing pleurisy |
| CN105963466A (en) * | 2016-06-17 | 2016-09-28 | 雷大鹏 | Traditional Chinese medicine enteric-coated tablet for treating immunodeficiency |
| CN106177013A (en) * | 2016-07-01 | 2016-12-07 | 雷大鹏 | A kind of capsule treating Lymphatic disease |
-
2003
- 2003-10-24 CN CNA2003101054439A patent/CN1537619A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103330901A (en) * | 2013-05-29 | 2013-10-02 | 陈松 | Chinese medicine for curing pleurisy |
| CN103330901B (en) * | 2013-05-29 | 2015-07-22 | 陈松 | Chinese medicine for curing pleurisy |
| CN105963466A (en) * | 2016-06-17 | 2016-09-28 | 雷大鹏 | Traditional Chinese medicine enteric-coated tablet for treating immunodeficiency |
| CN106177013A (en) * | 2016-07-01 | 2016-12-07 | 雷大鹏 | A kind of capsule treating Lymphatic disease |
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