CN102688434B - Traditional Chinese medicine (TCM) for treating diabetes - Google Patents
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Abstract
The invention relates to a traditional Chinese medicine (TCM) for treating diabetes. The TCM is prepared from radix rehmanniae, Chinese yam, cornus officinalis, cortex moutan, rhizoma alismatis, tuckahoe, radix astragali, angelica sinensis, salvia miltiorrhiza, hairyvein agrimonia herb and bud, potentilla discolor bge, safflower, leeches, red paeony root, pseudo-ginseng, winged euonymus twig, honeysuckle, mantis egg-case, sharpleaf galangal fruit and plantain seed. On the basis of the secret prescriptions handed down from the ancestors, in combination with summary of clinical experience of many years of the inventor and starting from the angles of nourishing the liver and kidney and promoting blood circulation to remove blood stasis, the TCM is obtained through repeated experiments by laying emphasis on searching for the primary cause of the disease in treatment and jointly conditioning the liver, kidney and spleen and applying the TCM to the patients with diabetes based on an overall analysis of the disease, so the TCM has unique curative effect on intractable diabetes, adopts scientific compatibility of multiple medicines and comprehensive treatment to ensure the active ingredients of the medicine to quickly enter the disease location to quickly correct glucose metabolic disorders and has the advantages of quick effect, short course of treatment, high cure rate and low cost.
Description
Technical field
The invention belongs to field of traditional Chinese, relate to a kind of Chinese medicine for the treatment of diabetes.
Background technology
Diabetes (diabetes) are by inherited genetic factors, immunologic function disorder, infected by microbes and toxin thereof, the free radical toxin, the various virulence factors of Nervous and Mental Factors etc. act on body and cause hypoinsulinism, insulin resistant etc. and the sugar that causes, protein, fat, a series of metabolism disorder syndromes such as power and water Xie Zhi, the hyperglycemia of take clinically is main feature, polyuria can appear in model case, polydipsia, polyphagia, the performance such as become thin, i.e. " three-many-one-little " symptom, diabetes (blood glucose) cause complication in case control bad meeting, cause kidney, eye, the exhaustion pathological changes at the positions such as foot, and can't cure.For many years, medical circle is devoted to the research to diabetes always, and this is in a single day body immunity reduces because suffer from diabetes, easily infects by flu, pneumonia, caused various the catching of pulmonary tuberculosis, and is difficult for healing.Diabetics, if glycemic control is bad, not only the life-span can reduce thereupon, and each organ of health there will be complication, when the patient felt that the complication in somewhere is obvious, the state of an illness of diabetes had developed into to a certain degree.
Primary disease adheres to that for a long time the standard treatment is most important, comprising: keep on a diet, and moderate exercise, rational use of drug.Common drug: chemical classes has Drugs Promoting Insulin Secretion, biguanides, AGI etc.; Or insulin injection.The said medicine side effect is large, easily produces drug resistance.Insulinize, with easily producing antibody, biological activity reduces for a long time, and metering increases, and produces hyperinsulinemia, promotes microangiopathic generation.
Motherland's medical science is thought the plain body deficiency of YIN, eating and drinking without temperance, obesity, disorder of emotion, depression of liver-QI, diseases caused by exogenous pathogenic factor six climate exopathogens, the evil infringement of poison is the principal element of bringing out primary disease, the normal scheme that adopts dialectical treatment, although some Chinese patent medicines appear on market, all not obvious on therapeutic effect.
Summary of the invention
The purpose of this invention is to provide that a kind of curative effect is fast, expense is low, the Chinese medicine of the treatment diabetes that have no side effect.
For realizing purpose of the present invention, existing according to following technical scheme, this Chinese medicine is made by the raw material of following weight portion proportioning:
8-10 parts of 10-15 parts of Cortex Moutans of 10-15 parts of Fructus Corni of 20-30 parts of Rhizoma Dioscoreaes of the Radix Rehmanniae
10-15 parts of 20-30 parts of Radix Angelicae Sinensis of 10-15 parts of Radixs Astragali of 10-15 parts of Poria of Rhizoma Alismatis
10-15 parts, 15-25 parts of Flos Carthamis of 15-25 parts of Herba Potentillae Discoloris of 10-15 parts of Herba Agrimoniaes of Radix Salviae Miltiorrhizae
10-15 parts of 5-10 parts of Ramulus Euonymis of 20-30 parts of Radix Notoginseng of 5-10 parts of Radix Paeoniae Rubra of Hirudo
10-15 parts of 10-15 parts of Fructus Alpiniae Oxyphyllae of 15-25 parts of Ootheca Mantidiss of 20-25 parts of Flos Loniceraes of the Radix Aucklandiae
10-15 parts of Semen Plantaginiss.
Preparation method of the present invention is: by prescription, take above-mentioned each Chinese medicine, then with pulverizer, pulverized 150 mesh sieves, flashing is that ball is as large as Semen phaseoli radiati, obtains.
Side separates:
The Radix Rehmanniae: clearing away heat and promoting production of body fluid, removing heat from blood, hemostasis, yin nourishing.For consumption of YIN caused by febrile disease, interior-heat is quenched one's thirst, and the crimson tongue excessive thirst is sent out the speckle dermexanthesis, spit blood, and epistaxis, laryngopharynx swelling and pain etc.
Rhizoma Dioscoreae: have stomach function regulating, tonifying the lung kidney, invigorating the spleen and replenishing QI, tonify deficiency, the effects such as beneficial essence, beneficial heart and tranquilizing mind of reinforcing the kidney.
Fructus Corni: liver and kidney tonifying, convergence astringent or styptic treatment for spontaneous sweating, controlling nocturnal emission with astringent drugs reducing urination, leukorrhagia stopping, only collapse, hidroschesis, promoting the production of body fluid to quench thirst.For soreness of waist and knee joint, dizziness and tinnitus, forgetful, emission and spermatorrhea, enuresis frequent micturition, bleeding not during menses, menoxenia, profuse sweating collapse, interior-heat, quench one's thirst etc.
Cortex Moutan: clearing away heat and cooling blood, promoting blood circulation to remove blood stasis.For deficiency of YIN osteopyrexia and fever, amenorrhea due to stagnation of blood, dysmenorrhea, carbuncle sore tumefacting virus, fall and flutter the pain of injury, rheumatism pyretic arthralgia etc.
Rhizoma Alismatis: promoting diuresis to eliminate damp pathogen, expel the heat-evil treating stranguria, for dysuria, the puckery pain of pyretic stranguria, edema distension, dizziness due to fluid-retention etc.
Poria: the function with promoting diuresis to eliminate damp pathogen, strengthening the spleen stomach function regulating, mind tranquilizing and the heart calming.Modern medicine study: Poria energy enhancing human body immunity function, pachyman have obvious antitumor and protect the liver dirty effect.
The Radix Astragali: the effect that benefiting QI for strengthening the superficies, arresting sweating are admittedly de-, hold in the palm skin ulcer granulation promoting, inducing diuresis to remove edema is arranged.Be used for the treatment of the deficiency of vital energy weak, sinking of QI of middle-JIAO, the chronic diarrhea proctoptosis, the metrorrhagia of having blood in stool, the exterior deficiency spontaneous perspiration, carbuncle is difficult bursts, and bursts and does not hold back for a long time, and blood deficiency and yellow complexion, interior-heat are quenched one's thirst etc.
Radix Angelicae Sinensis: enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.For blood deficiency and yellow complexion, dizzy cardiopalmus, asthenia cold abdominalgia etc.
Radix Salviae Miltiorrhizae: have promoting blood flow to regulate menstruation, stasis-dispelling and pain-killing, removing heat from blood eliminating carbuncle, the relieving restlessness that clears away heart-fire, the effect of nourishing blood to tranquillize the mind.
Herba Agrimoniae: astringing to arrest bleeding, dysentery relieving, parasite killing.Be widely used in various hemorrhage cards, modern medicine study has hypoglycemic activity.
Herba Potentillae Discoloris: heat-clearing and toxic substances removing, cooling blood for hemostasis.For enteritis, bacillary dysentery, amebic dysentery, spit blood, and epistaxis, have blood in stool, leucorrhea, and wound is controlled in external, carbuncle furuncle and phyma poison etc.Modern medicine study has hypoglycemic activity.
Flos Carthami: warm in nature, acrid in the mouth, the latus rectum of invigorating blood circulation, eliminating stasis to stop pain.For amenorrhea, dysmenorrhea, lochia, lump in the abdomen mass in the abdomen, traumatic injury etc.
Hirudo: removing blood stasis, removing blood stasis, stimulate the menstrual flow.Control blood-retention, gather, women's amenorrhea, blood stasis becomes consumptive disease, injury from falling down etc.
Radix Paeoniae Rubra: clots absorbing, pain relieving, removing heat from blood, detumescence.Cure mainly that the stagnant amenorrhea of the stasis of blood, hernia abdominal mass gather, stomachache, hypochondriac pain, epistaxis, dysentery, discharging fresh blood stool, conjunctival congestion, carbuncle, injury from falling down etc.
Radix Notoginseng: dissipating blood stasis hemostasis, subduing swelling and relieving pain.For various inside and outside hemorrhage, spitting of blood, spit blood, and epistaxis, have blood in stool, metrorrhagia, breast ventral spine pain, tumbling and swelling etc.
Ramulus Euonymi: promoting the circulation of blood is stimulated the menstrual flow, eliminating stasis to stop pain.For menoxenia, puerperal abdominalgia with blood stasis, traumatic injury swells and ache etc.
The Radix Aucklandiae: return spleen, stomach, liver, lung meridian.Have promoting the circulation of QI to relieve pain, intestinal stasis relieving effect in tune.
Flos Lonicerae: heat-clearing and toxic substances removing, wind-heat dissipating.For the carbuncle furuncle, sore throat, erysipelas, warm blood fulminant dysentery, anemopyretic cold, epidemic febrile disease heating etc.
Ootheca Mantidis: for emission due to deficiency of the kidney, premature ejaculation, sexual impotence, nebulousurine, be with inferior.
Fructus Alpiniae Oxyphyllae: warming the spleen, warming the kidney, solid and gas, arresting seminal emission.Control cold air stomachache, invasion by pathogenic cold is vomited and diarrhoea, many salivas, seminal emission, dribbling urination, night many urine etc.
Semen Plantaginis: clearing away heat and promoting diuresis, eliminating dampness by diuresis antidiarrheal, improving eyesight, eliminate the phlegm.Main dysuria, the stranguria with turbid discharge leukorrhagia, the edema distension, the heat-damp in summer dysentery, conjunctival congestion is hidden from view, and the expectorant heat syndrome cough is breathed heavily etc.
The present invention is that the inventor is on the basis of secret prescription handed down in the family from generation to generation, in conjunction with oneself summary of clinical experience for many years, angle from nourishing liver and kidney, blood circulation promoting and blood stasis dispelling, focus on treatment must aim at the pathogenesis of disease, liver,kidney,spleen is also adjusted, diagnosis and prescription is in the patient of diabetes, through repeatedly testing, obtain, therefore this medicine has unique curative effect to the intractable diabetes, it adopts multiple medicines science compatibility, comprehensive measure to make the active ingredient of medicine enter rapidly patient part, correct fast carbohydrate metabolism disturbance, have advantages of instant effect, short treating period, cure rate is high, expense is little.
The specific embodiment:
In following ratio, take raw material:
8-10 parts of 10-15 parts of Cortex Moutans of 10-15 parts of Fructus Corni of 20-30 parts of Rhizoma Dioscoreaes of the Radix Rehmanniae
10-15 parts of 20-30 parts of Radix Angelicae Sinensis of 10-15 parts of Radixs Astragali of 10-15 parts of Poria of Rhizoma Alismatis
10-15 parts, 15-25 parts of Flos Carthamis of 15-25 parts of Herba Potentillae Discoloris of 10-15 parts of Herba Agrimoniaes of Radix Salviae Miltiorrhizae
10-15 parts of 5-10 parts of Ramulus Euonymis of 20-30 parts of Radix Notoginseng of 5-10 parts of Radix Paeoniae Rubra of Hirudo
10-15 parts of 10-15 parts of Fructus Alpiniae Oxyphyllae of 15-25 parts of Ootheca Mantidiss of 20-25 parts of Flos Loniceraes of the Radix Aucklandiae
10-15 parts of Semen Plantaginiss.
Preparation method of the present invention is: by prescription, take above-mentioned each Chinese medicine, then with pulverizer, pulverized 150 mesh sieves, flashing is that ball is as large as Semen phaseoli radiati, obtains.
Using method of the present invention is: drug administration method of the present invention is: oral, and every day three times, each 6 grams, 30 minutes after meal decoction being taken warmly, one month is a course for the treatment of.During oral drugs, avoid eating anything raw or cold, pungent, greasy food, can take effect general 1-3 courses for the treatment of.
The experimental result of the present invention aspect blood sugar lowering
(1) physical dataChoose in JIUYUE, 2007～2010 year December wherein 200 routine type 2 diabetes mellitus patients to our hospital, age of onset is between 31～67 years old, and the shortest person of medical history is first visit, and the elder of medical history is 5 years.Select medical front patient's 150 examples without any Drug therapy, took patient's 50 examples of other antidiabetic drug treatment.Divide two groups at random, treatment group (Chinese medicine of the present invention) 100 examples, male's 55 examples, women's 45 examples; Matched group (SHENQI JIANGTANG KELI) 100 examples, male's 60 examples, women's 40 examples.
(2) clinical manifestationThe symptoms such as all cases all have in various degree xerostomia, thirsty, fatigue is weak, lower limb are aching and limp, light red, the thin fur of lumbago, night urine increased frequency, palm of the hand dysphoria with smothery sensation, body of the tongue, thready and rapid pulse.
(3), experimental technique
Prescription forms:
8-10 parts of 10-15 parts of Cortex Moutans of 10-15 parts of Fructus Corni of 20-30 parts of Rhizoma Dioscoreaes of the Radix Rehmanniae
10-15 parts of 20-30 parts of Radix Angelicae Sinensis of 10-15 parts of Radixs Astragali of 10-15 parts of Poria of Rhizoma Alismatis
10-15 parts, 15-25 parts of Flos Carthamis of 15-25 parts of Herba Potentillae Discoloris of 10-15 parts of Herba Agrimoniaes of Radix Salviae Miltiorrhizae
10-15 parts of 5-10 parts of Ramulus Euonymis of 20-30 parts of Radix Notoginseng of 5-10 parts of Radix Paeoniae Rubra of Hirudo
10-15 parts of 10-15 parts of Fructus Alpiniae Oxyphyllae of 15-25 parts of Ootheca Mantidiss of 20-25 parts of Flos Loniceraes of the Radix Aucklandiae
10-15 parts of Semen Plantaginiss, make blood-sugar lowering tcm drug.
Instructions of taking is: oral, and every day three times, each 6 grams, 30 minutes after meal decoction being taken warmly.
SHENQI JIANGTANG KELI, each one bag, 30 minutes after meal decoction being taken warmly.3 times on the one.
(4), criterion of therapeutical effect
With reference to " new Chinese medicine guideline of clinical investigations " formulation standard.Clinical cure: after treatment, symptom disappears substantially, fasting glucose<7.26mmol/L, and 2 h blood glucose<8.3 mmol/L or blood sugar quantitative are treated front decline >=30% after the meal.Effectively: before and after treatment, symptom is obviously improved, fasting glucose<8.3 mmol/L, and 2 h blood glucose<10.0 mmol/L or blood sugar quantitative are treated front decline≤10% ~ 30% after the meal.Invalid: before and after treatment, symptom is not improved, and blood glucose descends and do not reach above-mentioned standard.
(5), therapeutic outcome
Two groups of patient clinical symptoms are clearly better, and every biochemical indicator significantly improves, and glucose in urine is all negative, fasting glucose and 2h-plasma glucose treat front remarkable reduction (
P<0.01).Treatment group clinical cure rate 60%, effective 97%, inefficiency 3%; Matched group clinical cure rate 35%, effective 84 rate %, inefficiency 16%.Treatment group be better than matched group (
P<0.01).Before and after two groups of diabetic therapy, curative effect is relatively in Table 5.1, and Main Biochemical is relatively in Table 5.2, and all experimental datas are all used the SPSS12.0 statistical software to carry out statistical procedures.
Table 5.1 liang group diabetics curative effect relatively
| Group | Number of cases | Clinical cure | Effectively | Invalid | Total effective rate (%) |
| Treatment group | 100 | 60 | 97 | 3 | 97.0 |
| Matched group | 100 | 35 | 84 | 16 | 84.0 |
Annotate: two groups of curative effects relatively, difference have statistical significance (
P<0.01)
Before and after table 5.2 liang group diabetic therapy, Main Biochemical compares (mmol/L)
Annotate: after the treatment of * treatment group, compare with fasting glucose before treatment,
P<0.01; After the * treatment of control group, compare with fasting glucose before treatment,
P<0.01;
▲After the treatment group treatment, compare with 2h-plasma glucose before treatment,
P<0.01;
▲ ▲After treatment of control group, compare with 2h-plasma glucose before treatment,
P<0.01
Diabetes spp is in motherland's medical science category of quenching one's thirst, and motherland's medical science thinks, diabetes (diabetes) is that TCM treatment of diabetes be take organic conception, determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs as main by natural endowment is not enough, body constitution is weak and the coefficient result of acquired disposition.Primary disease starts from the deficiency of YIN, arises from scorchingly, and deficiency of YIN emphasis, at kidney, is it, and the scorching lung stomach that shows, be its mark, both reciprocal causations, cloudy more empty scorchingly more contain, scorching more contain cloudy more empty.With the passing of time primary disease delay does not heal, and often can involve the five internal organs, causes the essence and blood exhaustion, and negative and positive all decline, and accumulates and concurrent multiple double disease in scorching.Therefore in treatment, answer treating both the principal and secondary aspects of a disease, the YIN nourishing of take is reinforced the kidney as main, adopt the principle of clearing away heat and nourishing YIN, nourishing liver and kidney, blood circulation promoting and blood stasis dispelling, adjust the human internal environment, improve patient's metabolism status.Medicine of the present invention can make degeneration, edema, Fibrotic islet tissue be repaired, but improves quantity and the function of the β cell of excreting insulin.Any untoward reaction does not appear during Drug therapy of the present invention, method safety, and evident in efficacy.
Claims (2)
1. Chinese medicine for the treatment of diabetes is characterized in that it is to be made by the raw material of following weight portion proportioning:
8-10 parts of 10-15 parts of Cortex Moutans of 10-15 parts of Fructus Corni of 20-30 parts of Rhizoma Dioscoreaes of the Radix Rehmanniae
10-15 parts of 20-30 parts of Radix Angelicae Sinensis of 10-15 parts of Radixs Astragali of 10-15 parts of Poria of Rhizoma Alismatis
10-15 parts, 15-25 parts of Flos Carthamis of 15-25 parts of Herba Potentillae Discoloris of 10-15 parts of Herba Agrimoniaes of Radix Salviae Miltiorrhizae
10-15 parts of 5-10 parts of Ramulus Euonymis of 20-30 parts of Radix Notoginseng of 5-10 parts of Radix Paeoniae Rubra of Hirudo
10-15 parts of 10-15 parts of Fructus Alpiniae Oxyphyllae of 15-25 parts of Ootheca Mantidiss of 20-25 parts of Flos Loniceraes of the Radix Aucklandiae
10-15 parts of Semen Plantaginiss.
2. a kind of preparation method for the treatment of the Chinese medicine of diabetes according to claim 1, it is characterized in that: by prescription, take above-mentioned each Chinese medicine, then with pulverizer, pulverized 150 mesh sieves, flashing is that ball is as large as Semen phaseoli radiati, obtains.
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| CN100509025C (en) * | 2006-05-18 | 2009-07-08 | 张将勇 | A medicine for treating diabetes |
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