CN1537558A - Traditional Chinese medicine for treating blood viscosity - Google Patents

Traditional Chinese medicine for treating blood viscosity Download PDF

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Publication number
CN1537558A
CN1537558A CNA031114768A CN03111476A CN1537558A CN 1537558 A CN1537558 A CN 1537558A CN A031114768 A CNA031114768 A CN A031114768A CN 03111476 A CN03111476 A CN 03111476A CN 1537558 A CN1537558 A CN 1537558A
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China
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parts
chinese medicine
rhizoma
traditional chinese
blood viscosity
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CNA031114768A
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Chinese (zh)
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铁 于
于铁
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Individual
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Individual
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Priority to CNA031114768A priority Critical patent/CN1537558A/en
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Abstract

A Chinese medicine in the form of capsule or decoction for treating hyperviscosity blood, hyperlipemia and fatty liver is prepared from 17-19 Chinese-medicinal materials including pinellia tuber, haw, tangerine peel, red sage root, etc. Its advantages are high curative effect (82% for cure rate) and quickly taking it effect.

Description

Traditional Chinese medicine for treating blood viscosity
Technical field
The present invention relates to the field of Chinese medicines, be specifically related to the condensed Chinese medicine of a kind of treatment blood.
Background technology
The thick disease of blood is common clinical at present, and it shows as dizziness headache or dizzy cranial tinnitus, chest distress and palpitation symptoms, nauseating feeling of fullness a series of symptoms such as do not relax.Clinical physico-chemical examination shows as blood examination more and occurs unusual.About to " blood is thick " treatment of diseases, this all has very important meaning to cardio-cerebrovascular disorder, geriatrics and preventive medicine aspect.Generally use PSS (propylene glycol alginate sodium sulfate) and vitamin E nicotinate capsule treatment according to the domestic and foreign literature introduction.And medical circles find according to retrieval in domestic, and treatment by Chinese herbs generally all is main the treatment with the blood circulation promoting and blood stasis dispelling.The inventor thinks that the thick class disease of activating blood and resolving stasis and treating blood can only take stopgap measures, just the research of aspects such as hemodynamics and ignored treatment to it emphatically.
Summary of the invention
The object of the present invention is to provide the compound preparation of the thick disease of a kind of effective treatment blood, the inventor also is exactly the research of having strengthened aspect the lipid metabolism in the research to it, execute on the basis of controlling at differential diagnosis in tcm, in conjunction with this sick clinical characters, eliminate the phlegm based on spleen invigorating, blood circulation promoting and blood stasis dispelling is auxilliary, makes laws with treating both the principal and secondary aspects of a disease, adopt the thick class disease of the thick preparation for treating blood of Chinese medicine compound blood, this is inventor's theory innovation part.
Crude drug of the present invention selects the Rhizoma Pinelliae, Semen Sinapis Albae, Fructus Crataegi, Massa Medicata Fermentata, the Rhizoma Atractylodis Macrocephalae, Poria, Rhizoma Acori Graminei, Pericarpium Citri Reticulatae, the Radix Polygoni Multiflori, the Radix Angelicae Dahuricae, Fructus Lycii, Pericarpium Trichosanthis, Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae, Semen Cassiae, Folium Nelumbinis and Radix Glycyrrhizae to combine, make each efficacy of drugs produce synergism these drug regimens, thereby can effectively treat the thick disease of blood.Wherein the Rhizoma Pinelliae, Semen Sinapis Albae, Pericarpium Trichosanthis eliminate the phlegm and are principal agent; Folium Nelumbinis, Semen Cassiae effect for reducing fat; The Rhizoma Atractylodis Macrocephalae, Poria, Massa Medicata Fermentata, Pericarpium Citri Reticulatae, Fructus Crataegi strengthening the spleen to promote digestion; Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong blood circulation promoting and blood stasis dispelling are auxilliary; Assistant with Rhizoma Acori Graminei, Radix Angelicae Dahuricae eliminating turbid pathogen with aromatics to have one's ideas straightened out; The Radix Polygoni Multiflori, Fructus Lycii nourishing YIN and benefiting blood make with the Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription in case principal agent has the mistake of dampness impairment of YIN.
The consumption of raw material components of the present invention carries out a large amount of experimental summaries through the inventor and draws, and the each component consumption has better curative effect in following weight proportion scope:
1.5 parts in 3 parts of the Rhizoma Pinelliaes, 3 parts of Semen Sinapis Albaes, 3 parts of Fructus Crataegis, 3 parts of Massa Medicata Fermentata, 3 parts of the Rhizoma Atractylodis Macrocephalaes, 3 parts in Poria, 2 parts of Rhizoma Acori Graminei, 2 parts of Pericarpium Citri Reticulataes, 3 parts of the Radixs Polygoni Multiflori, 2 parts of the Radixs Angelicae Dahuricae, 3 parts of Fructus Lycii, 3 parts of Pericarpium Trichosanthiss, 3 parts of Rhizoma Chuanxiongs, 3 parts of Radix Salviae Miltiorrhizaes, 3 parts of Semen Cassiae, 5 parts on Folium Nelumbinis and Radix Glycyrrhizae.
In crude drug of the present invention, add 3 parts of Radix Bupleuri, 3 parts of Radix Curcumaes, can treat fatty liver effectively.
Crude drug of the present invention can adopt the conventional method of Chinese medicine preparation to be prepared into, and incapsulates or make Chinese medicine decoction as pulverize.Drug main of the present invention will be treated high blood viscosity and hyperlipemia, instant effect, and cure rate reaches 82%, and total effective rate reaches 100%.
The specific embodiment
Below further set forth the beneficial effect of medicine of the present invention by testing example, these tests have comprised that the pharmacodynamics test of medicine of the present invention and clinical observation on the therapeutic effect test.
1, the The acute toxicity tests of Traditional Chinese medicine for treating blood viscosity shows, said preparation has no side effect, clinical drug safety.
2, zooperal morphological observation result shows; the body weight change of white mice does not have significant difference before and after the experiment; liver then has the significance difference opposite sex of height; illustrated that Traditional Chinese medicine for treating blood viscosity does not only have any detrimental effect to substantial viscera, one of vitals of opposing the participation lipid metabolism mutually also have the certain protection effect.
3, we use the clinical observation of said preparation to 81 routine high blood viscosity treatments clinically
(1). physical data
The thick patient of 81 routine blood all is that my gate is examined and the inpatient, male's 42 examples, and women's 39 examples at 30~70 years old age, average 56.8 years old, wherein have cardiovascular and cerebrovascular disease history 20 examples.
(2). diagnostic criteria
The hemorheological every average normal reference value that carries with practical internal medicine is as the criterion, and through the hemorheology inspection, every index surpasses normal value person.
(3). Therapeutic Method
Every day oral Chinese medicine compound recipe blood thick glue capsule, 3 times on the 1st, each 5~7,30 was 1 course of treatment.
(4). curative effect determinate standard
Clinical recovery: clinical symptom disappearance such as dizzy cranial tinnitus, cardiopalmus are uncomfortable in chest, numb limbs and tense tendons, drowsiness greasy fur; It is normal that hemorheological indexes is recovered; Clinical symptoms such as effective dizzy cranial tinnitus, cardiopalmus are uncomfortable in chest, numb limbs and tense tendons, drowsiness greasy fur all take a favorable turn; Hemorheology is learned every index does not have improvement.
(5). therapeutic outcome
The thick curative effect statistics of table 1 Traditional Chinese medicine for treating blood viscosity treatment blood
Cure Effectively Invalid
Cardiovascular and cerebrovascular vessel are arranged ????16 ????4 ????0
Disease 20 examples ????80% ????20% ????0
No cardiovascular and cerebrovascular vessel ????50 ????11 ????0
Disease 61 examples ????82% ????18% ????0
Add up to ????66 ????15 ????0
????81.5% ????18.5% ????0
Hemorheology was observed before and after table 2 was taken medicine
Project Before the clothes Behind the clothes The P value
????ηb ????5.28±0.94 ????4.94±1.18 ????<0.01
????HCT ????0.54±0.1 ????0.49±0.12 ????<0.00
????ηR ????7.85±0.90 ????7.51±1.52 ????<0.03
????ηP ????1.55±0.22 ????1.48±0.34 ????<0.05
????PFC ????2.98±0.70 ????2.66±0.62 ????<0.001
????IR ????4.24±0.74 ????4.01±1.0 ????<0.05
????TK ????2.23±0.30 ????1.14±0.28 ????<0.01
????VAI ????0.74±0.22 ????0.69±0.24 ??0.1>P>0.05
????MST ????25.05±10.98 ????20.8±12.94 ????<0.005
????TEL ????0.77±0.28 ????0.68±0.28 ????<0.01
(6). brief summary
The inventor is to the oral Chinese medicine compound recipe blood thick capsular treatment of 81 routine high blood viscosity patients through a course of treatment, find that this medicine has the erythrocyte of inhibition and platelet aggregation, blood viscosity lowering, the effect of microcirculation improvement, and patient's clinical symptoms all is significantly improved even disappears, hemorheological every index is learned by statistics to handle and is shown the treatment of compound recipe blood thick glue capsule to the high blood viscosity patient, except that the VAI item do not have show unusually, all other indexs all have the highly significant diversity.

Claims (2)

1, Traditional Chinese medicine for treating blood viscosity is characterized in that: it is processed into powder with the following weight proportion raw material or decoction is made: 1.5 parts in 3 parts of the Rhizoma Pinelliaes, 3 parts of Semen Sinapis Albaes, 3 parts of Fructus Crataegis, 3 parts of Massa Medicata Fermentata, 3 parts of the Rhizoma Atractylodis Macrocephalaes, 3 parts in Poria, 2 parts of Rhizoma Acori Graminei, 2 parts of Pericarpium Citri Reticulataes, 3 parts of the Radixs Polygoni Multiflori, 2 parts of the Radixs Angelicae Dahuricae, 3 parts of Fructus Lycii, 3 parts of Pericarpium Trichosanthiss, 3 parts of Rhizoma Chuanxiongs, 3 parts of Radix Salviae Miltiorrhizaes, 3 parts of Semen Cassiae, 5 parts on Folium Nelumbinis and Radix Glycyrrhizae.
2, Traditional Chinese medicine for treating blood viscosity according to claim 1 is characterized in that: add 3 parts of Radix Bupleuri, 3 parts of Radix Curcumaes, can treat fatty liver.
CNA031114768A 2003-04-14 2003-04-14 Traditional Chinese medicine for treating blood viscosity Pending CN1537558A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CNA031114768A CN1537558A (en) 2003-04-14 2003-04-14 Traditional Chinese medicine for treating blood viscosity

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Application Number Priority Date Filing Date Title
CNA031114768A CN1537558A (en) 2003-04-14 2003-04-14 Traditional Chinese medicine for treating blood viscosity

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CN1537558A true CN1537558A (en) 2004-10-20

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101401925B (en) * 2008-11-06 2012-07-18 贾延莹 Traditional Chinese medicine decoction for treating fatty liver
CN104258026A (en) * 2014-09-16 2015-01-07 苏州市天灵中药饮片有限公司 Blood fat-reducing traditional Chinese medicine composition and preparation method thereof
CN116983377A (en) * 2023-08-31 2023-11-03 苏州市吴江区中医医院(苏州市吴江区第二人民医院) Traditional Chinese medicine composition, preparation and application for treating non-alcoholic fatty liver disease with syndrome of internal stagnation of phlegm

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101401925B (en) * 2008-11-06 2012-07-18 贾延莹 Traditional Chinese medicine decoction for treating fatty liver
CN104258026A (en) * 2014-09-16 2015-01-07 苏州市天灵中药饮片有限公司 Blood fat-reducing traditional Chinese medicine composition and preparation method thereof
CN116983377A (en) * 2023-08-31 2023-11-03 苏州市吴江区中医医院(苏州市吴江区第二人民医院) Traditional Chinese medicine composition, preparation and application for treating non-alcoholic fatty liver disease with syndrome of internal stagnation of phlegm

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