CN1528386A - Chinese medicine composition for treating rheumatism, rheumatoid, hyperosteogeny and fracture and preparing method thereof - Google Patents
Chinese medicine composition for treating rheumatism, rheumatoid, hyperosteogeny and fracture and preparing method thereof Download PDFInfo
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- CN1528386A CN1528386A CNA031576001A CN03157600A CN1528386A CN 1528386 A CN1528386 A CN 1528386A CN A031576001 A CNA031576001 A CN A031576001A CN 03157600 A CN03157600 A CN 03157600A CN 1528386 A CN1528386 A CN 1528386A
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Abstract
The present invention discloses a Chinese medicine composition for curing the diseases of rheumatism, rheumatoid disease, hyperosteogeny and fracture and its preparation method. Said Chinese medicine composition is formed from 42 Chinese medicinal materials of borneol, camphor, musk raw aconite main tuber, raw wild aconite tuber, nux vomica and others. Its preparation method includes the following steps: dividing the above-mentioned 42 Chinese medicinal materials into three classes, grinding class A and class B to obtain fine powder respectively, decocting and concentrating class C to obtain extract for stand-by, then placing said extract into medicinal oil, boiling to remove water content, and then placing the said medicinal powders into the above-mentioned extract, stirring.
Description
Technical field
The present invention relates to a kind of pharmaceutical composition, particularly relate to a kind of Chinese medicine composition for the treatment of rheumatism, rheumatoid, hyperosteogeny and fracture and preparation method thereof.
Background technology
Forcing on is external treatment, belongs to " epigenesist is controlled outer ", and it sees through medicine to internal organs by body surface.Withered removing slag endured in the preparation of traditional black plaster, spice usually, and medicine oil is tempered and often reached 320～330 degrees centigrade, and the temperature behind the following pellet can reach 360 degrees centigrade, high temperature like this, and the many effective ingredient in the spice are destroyed, thereby many crude drug are absorbed.
Technology contents
The object of the present invention is to provide a kind of Chinese medicine composition to treatment rheumatism, rheumatoid, hyperosteogeny and fracture and preparation method thereof.
The present invention is achieved through the following technical solutions:
Choose crude drug
One class medicine: Borneolum Syntheticum 1-5 weight portion Camphora 4-15 weight portion Moschus 0.5-2 weight portion
Two class medicines: Radix Aconiti 6-20 weight portion Radix Aconiti Kusnezoffii 6-20 weight portion Semen Strychni 8-23 weight portion
Flos Caryophylli 2-8 weight portion Cortex Cinnamomi 5-15 weight portion Herba Asari 8-23 weight portion
Olibanum 8-23 weight portion Myrrha 8-23 weight portion Sanguis Draxonis 8-23 weight portion
Scorpio 3-10 weight portion Scolopendra 3-10 weight portion Squama Manis 8-23 weight portion
Radix Notoginseng 6-20 weight portion Rhizoma Acori Graminei 4-12 weight portion
Three class medicines: Radix Clematidis 6-20 weight portion Semen Persicae 3-10 weight portion Flos Carthami 3-10 weight portion
Eupolyphaga Seu Steleophaga 4-12 weight portion Radix Angelicae Sinensis 5-15 weight portion rhizoma sparganic 3-10 weight portion
Rhizoma Curcumae 3-10 weight portion Radix Zanthoxyli 8-23 weight portion Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 8-23 weight portion
The Caulis Trachelospermi 8-25 weight portion Radix Saposhnikoviae 3-10 weight portion Wan 6-20 of Qin weight portion
Caulis Spatholobi 8-23 weight portion Rhizoma Cibotii 8-23 weight portion Herba Pyrolae 8-23 weight portion
Rhizoma Drynariae 8-23 weight portion Herba Ephedrae 6-20 weight portion Cortex Dictamni 5-15 weight portion
Nidus Vespae 8-23 weight portion Rhizoma Corydalis 3-10 weight portion Radix Angelicae Dahuricae 5-15 weight portion
Cortex Acanthopancis 8-23 weight portion Fructus Gardeniae 3-10 weight portion Cortex cercis chinensis 3-10 weight portion
Semen Phaseoli 5-15 weight portion
Optimum ratio of the present invention is:
Choose crude drug
One class medicine: Borneolum Syntheticum 3 weight portion Camphoras 9 weight portion Moschus 1 weight portion
Two class medicines: Radix Aconiti 12 weight portion Radix Aconiti Kusnezoffii 12 weight portion Semen Strychni 12 weight portions
Flos Caryophylli 5 weight portion Cortex Cinnamomis 10 weight portion Herba Asaris 15 weight portions
Olibanum 15 weight portion Myrrha 15 weight portion Sanguis Draxonis 15 weight portions
Scorpio 7 weight portion Scolopendras 7 weight portion Squama Maniss 15 weight portions
Radix Notoginseng 12 weight portion Rhizoma Acori Gramineis 8 weight portions
Three class medicines: Radix Clematidis 12 weight portion Semen Persicaes 7 weight portion Flos Carthamis 7 weight portions
Eupolyphaga Seu Steleophaga 8 weight portion Radix Angelicae Sinensis 10 weight portion rhizoma sparganic 7 weight portions
Rhizoma Curcumae 7 weight portion Radix Zanthoxylis 15 weight portion Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae)s 15 weight portions
Caulis Trachelospermi 15 weight portion Radix Saposhnikoviaes 7 Wan of the weight portion Qin 12 weight portions
Caulis Spatholobi 12 weight portion Rhizoma Cibotii 15 weight portion Herba Pyrolaes 15 weight portions
Rhizoma Drynariae 15 weight portion Herba Ephedraes 12 weight portion Cortex Dictamnis 10 weight portions
The Nidus Vespae 15 weight portion Rhizoma Corydalis 7 weight portion Radixs Angelicae Dahuricae 10 weight portions
Cortex Acanthopancis 15 weight portion Fructus Gardeniaes 7 weight portion Cortex cercis chinensiss 7 weight portions
Semen Phaseoli 10 weight portions
The fragrant odour that produce in the preferred Liaoning of described Herba Asari, Jilin, Heilungkiang, the Herba Asari of the peppery and numb tongue of acrid in the mouth.
With the first kind, that the second class crude drug is processed into impalpable powder respectively is standby; Again the 3rd quasi drugs is processed into coarse powder, adds water 3-5 time, each 30-70 minute, decocting liquid is merged precipitation consider after 20-30 hour and get supernatant concentration, concentrated solution is fried in shallow oil into the thick paste shape with slow fire, having ladled out reversal of the natural order of things standby with spades is extractum;
Plaster substrate be prepared as earlier 200-400 weight portion Plumbum preparatium or peach pellet, Plumbum preparatium, Plumbum preparatium, that Plumbum preparatium is fried purple is standby; Other edible vegetable oil 500-800 weight portion that again will be except that Oleum Glycines, put into dark iron pan, heating is tempered, temper to 300-330 degree centigrade, slowly put into Plumbum preparatium, excitor substances such as the aldehyde that produces in the alseodaphne hainanensis chemical combination process, ketone are removed from cream, black plaster substrate heat fused, suitably temper, to remove moisture; Extractum thermoplastic with the preparation of the 3rd class spice; Spice, the extractum impouring of heating and melting are chilled in about 70 degrees centigrade substrate, endure moisture in the extractum with slow fire, reduce to 70 degree from fire again, the second class medicated powder descends first kind medicated powder fully to mix at last and makes obedient cream down.Every subsides 30 grams.
Pharmaceutical composition of the present invention has the function effect of removing cold and wind damp, liver and kidney tonifying, promoting blood circulation to remove obstruction in the collateral, and is remarkable to treatment rheumatism, rheumatoid, hyperosteogeny and fracture effect.
Pharmaceutical composition of the present invention can be made into acceptable forms clinically, as spray.
Clinical data:
1, Radix Clematidis cream of the present invention is treated all kinds of hyperosteogeny 400 routine patients, and age of onset was seen between 33 years old-70 years old more, male's 170 examples; Women's 230 routine courses of disease are the longest 13 years, and are the shortest 2 months; Site of pathological change (cervical vertebra, lumbar vertebra) clinical symptoms is seen more.Cervical vertebra is sent out the patient all ceruical uertebra part pain upper limb numbness, moving obstacle to the left and right, and tenderness is obvious; Lumbar vertebra morbidity patient all has lumbago to bend and stretch function, moving obstacle, waist tenderness and lower limb radiation, movable back, and the pain increased or subtract etc.Treatment was changed dressings once with every 30 gram of Ben Faken Radix Clematidis cream in 3 days; The shortest subsides of treatment time 1 month, the longest 9 months; Therapeutic outcome 315 examples of fully recovering, effective 65 examples, invalid 17 examples, effective percentage 95.75%.
2, Radix Clematidis cream of the present invention treatment rheumatoid patient 120 examples, every 30 gram changed dressings that it is the shortest 3 months once to paste the arthralgia position course of disease in 3 days, maximum duration 11 years.Treatment time the shortest subsides Radix Clematidis cream 1 month, the longest subsides 9 months, the result cures 69 examples, effective 38 imitate example, invalid 13 examples, effective percentage 89.17%.
3, Radix Clematidis cream of the present invention is treated all kinds of fracture 135 examples,,, changed dressings once in 3 days to disappear in the accurate swelling that resets with every 30 gram of Radix Clematidis cream, and the shortest subsides Radix Clematidis cream 2 months, the longest subsides 5 months, the 135 examples portion of fullying recover from an illness cures, and effective percentage is 100%
4, Radix Clematidis cream of the present invention is treated the fracture time with 48 examples of a specified duration, and callus does not form, bone does not connect is given birth to, minimum 32 years old of age, the oldest 89 years old.With every 30 gram of Radix Clematidis cream of the present invention, changed dressings once in 3 days; 2 first quarter moons of the shortest subsides of treatment time as a result, the longest subsides 9 months, 48 examples are all cured, and effective percentage is 100%
Embodiment
One class medicine: Borneolum Syntheticum 3g Camphora 9g Moschus 1g
Two class medicines: Radix Aconiti 12g Radix Aconiti Kusnezoffii 12g Semen Strychni 12g Flos Caryophylli 5g Cortex Cinnamomi 10g
Herba Asari 15g Olibanum 15g Myrrha 15g Sanguis Draxonis 15g Scorpio 7g
Scolopendra 7g Squama Manis 15g Radix Notoginseng 12g Rhizoma Acori Graminei 8g
Three class medicines: Radix Clematidis 12g Semen Persicae 7g Flos Carthami 7g Eupolyphaga Seu Steleophaga 8g Radix Angelicae Sinensis 10g
Rhizoma sparganic 7g Rhizoma Curcumae 7g Radix Zanthoxyli 15g Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 15g Caulis Trachelospermi 15g
The Wan 12g of Radix Saposhnikoviae 7g Qin Caulis Spatholobi 12g Rhizoma Cibotii 15g Herba Pyrolae 15g
Rhizoma Drynariae 15g Herba Ephedrae 12g Cortex Dictamni 10g Nidus Vespae 15g Rhizoma Corydalis 7g
Radix Angelicae Dahuricae 10g Cortex Acanthopancis 15g Fructus Gardeniae 7g Cortex cercis chinensis 7g Semen Phaseoli 10g
With the first kind, that the second class crude drug is processed into impalpable powder respectively is standby; Again the 3rd quasi drugs is processed into coarse powder, adds water 4 times, each 50 minutes, decocting liquid is merged precipitation consider after 24 hours and get supernatant concentration, concentrated solution is fried in shallow oil into the thick paste shape with slow fire, having ladled out reversal of the natural order of things standby with spades is extractum;
Being prepared as of plaster substrate is standby with 300g Plumbum preparatium stir-fry purple earlier; Other edible vegetable oil 670g that again will be except that Oleum Glycines, put into dark iron pan, heating is tempered, temper to 320-330 degree centigrade, slowly put into Plumbum preparatium, excitor substances such as the aldehyde that produces in the alseodaphne hainanensis chemical combination process, ketone are removed from cream, black plaster substrate heat fused, suitably temper, to remove moisture; Extractum thermoplastic with the preparation of the 3rd class spice; Spice, the extractum impouring of heating and melting are chilled in about 70 degrees centigrade substrate, endure moisture in the extractum with slow fire, reduce to 70 degree from fire again, the second class medicated powder descends first kind medicated powder fully to mix at last and makes obedient cream down.Every subsides 30 grams.
Claims (6)
1, a kind of Chinese medicine composition for the treatment of rheumatism, rheumatoid, hyperosteogeny and fracture and preparation method thereof is characterized in that said composition mainly is made up of following crude drug:
One class medicine: Borneolum Syntheticum 1-5 weight portion Camphora 4-15 weight portion Moschus 0.5-2 weight portion
Two class medicines: Radix Aconiti 6-20 weight portion Radix Aconiti Kusnezoffii 6-20 weight portion Semen Strychni 8-23 weight portion
Flos Caryophylli 2-8 weight portion Cortex Cinnamomi 5-15 weight portion Herba Asari 8-23 weight portion
Olibanum 8-23 weight portion Myrrha 8-23 weight portion Sanguis Draxonis 8-23 weight portion
Scorpio 3-10 weight portion Scolopendra 3-10 weight portion Squama Manis 8-23 weight portion
Radix Notoginseng 6-20 weight portion Rhizoma Acori Graminei 4-12 weight portion
Three class medicines: Radix Clematidis 6-20 weight portion Semen Persicae 3-10 weight portion Flos Carthami 3-10 weight portion
Eupolyphaga Seu Steleophaga 4-12 weight portion Radix Angelicae Sinensis 5-15 weight portion rhizoma sparganic 3-10 weight portion
Rhizoma Curcumae 3-10 weight portion Radix Zanthoxyli 8-23 weight portion Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 8-23 weight portion
The Caulis Trachelospermi 8-25 weight portion Radix Saposhnikoviae 3-10 weight portion Wan 6-20 of Qin weight portion
Caulis Spatholobi 8-23 weight portion Rhizoma Cibotii 8-23 weight portion Herba Pyrolae 8-23 weight portion
Rhizoma Drynariae 8-23 weight portion Herba Ephedrae 6-20 weight portion Cortex Dictamni 5-15 weight portion
Nidus Vespae 8-23 weight portion Rhizoma Corydalis 3-10 weight portion Radix Angelicae Dahuricae 5-15 weight portion
Cortex Acanthopancis 8-23 weight portion Fructus Gardeniae 3-10 weight portion Cortex cercis chinensis 3-10 weight portion
Semen Phaseoli 5-15 weight portion.
2, Chinese medicine composition according to claim 1 is characterized in that said composition is mainly to be made up of following raw material medicaments:
One class medicine: Borneolum Syntheticum 3 weight portion Camphoras 9 weight portion Moschus 1 weight portion
Two class medicines: Radix Aconiti 12 weight portion Radix Aconiti Kusnezoffii 12 weight portion Semen Strychni 12 weight portions
Flos Caryophylli 5 weight portion Cortex Cinnamomis 10 weight portion Herba Asaris 15 weight portions
Olibanum 15 weight portion Myrrha 15 weight portion Sanguis Draxonis 15 weight portions
Scorpio 7 weight portion Scolopendras 7 weight portion Squama Maniss 15 weight portions
Radix Notoginseng 12 weight portion Rhizoma Acori Gramineis 8 weight portions
Three class medicines: Radix Clematidis 12 weight portion Semen Persicaes 7 weight portion Flos Carthamis 7 weight portions
Eupolyphaga Seu Steleophaga 8 weight portion Radix Angelicae Sinensis 10 weight portion rhizoma sparganic 7 weight portions
Rhizoma Curcumae 7 weight portion Radix Zanthoxylis 15 weight portion Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae)s 15 weight portions
Caulis Trachelospermi 15 weight portion Radix Saposhnikoviaes 7 Wan of the weight portion Qin 12 weight portions
Caulis Spatholobi 12 weight portion Rhizoma Cibotii 15 weight portion Herba Pyrolaes 15 weight portions
Rhizoma Drynariae 15 weight portion Herba Ephedraes 12 weight portion Cortex Dictamnis 10 weight portions
The Nidus Vespae 15 weight portion Rhizoma Corydalis 7 weight portion Radixs Angelicae Dahuricae 10 weight portions
Cortex Acanthopancis 15 weight portion Fructus Gardeniaes 7 weight portion Cortex cercis chinensiss 7 weight portions
Semen Phaseoli 10 weight portions.
3, pharmaceutical composition according to claim 1 and 2 is characterized in that the fragrant odour that produces in the preferred Liaoning of described Herba Asari, Jilin, Heilungkiang, the Herba Asari of the peppery and numb tongue of acrid in the mouth.
4, pharmaceutical composition according to claim 1 and 2 is characterized in that this combination adds adjuvant and can be made into the dosage form of accepting clinically, as spray agent.
5,1 or 2 described preparation of drug combination methods as requested is characterized in that this preparation method is: with the first kind, that the second class crude drug is processed into impalpable powder respectively is standby; Again the 3rd quasi drugs is processed into coarse powder, adds water 3-5 time, each 30-70 minute, decocting liquid is merged precipitation consider after 20-30 hour and get supernatant concentration, concentrated solution is fried in shallow oil into the thick paste shape with slow fire, having ladled out reversal of the natural order of things standby with spades is extractum;
Plaster substrate be prepared as earlier 200-400 weight portion Plumbum preparatium or peach pellet, Plumbum preparatium, Plumbum preparatium, that Plumbum preparatium is fried purple is standby; Other edible vegetable oil 500-800 weight portion that again will be except that Oleum Glycines, put into dark iron pan, heating is tempered, temper to 300-330 degree centigrade, slowly put into Plumbum preparatium, excitor substances such as the aldehyde that produces in the alseodaphne hainanensis chemical combination process, ketone are removed from cream, black plaster substrate heat fused, suitably temper, to remove moisture; Extractum thermoplastic with the preparation of the 3rd class spice; Spice, the extractum impouring of heating and melting are chilled in about 70 degrees centigrade substrate, endure moisture in the extractum with slow fire, reduce to 70 degree from fire again, the second class medicated powder descends first kind medicated powder fully to mix at last and makes obedient cream down.
6, preparation method according to claim 4, it is characterized in that this method for the first kind, that the second class crude drug is processed into impalpable powder respectively is standby; Again the 3rd quasi drugs is processed into coarse powder, adds water 4 times, each 50 minutes, decocting liquid is merged precipitation consider after 24 hours and get supernatant concentration, concentrated solution is fried in shallow oil into the thick paste shape with slow fire, having ladled out reversal of the natural order of things standby with spades is extractum;
Plaster substrate be prepared as earlier 300 weight portion Plumbum preparatium or peach pellet, Plumbum preparatium, Plumbum preparatium, that Plumbum preparatium is fried purple is standby; Other edible vegetable oil 670 weight portions that again will be except that Oleum Glycines, put into dark iron pan, heating is tempered, temper to 320-330 degree centigrade, slowly put into Plumbum preparatium, excitor substances such as the aldehyde that produces in the alseodaphne hainanensis chemical combination process, ketone are removed from cream, black plaster substrate heat fused, suitably temper, to remove moisture; Extractum thermoplastic with the preparation of the 3rd class spice; Spice, the extractum impouring of heating and melting are chilled in about 70 degrees centigrade substrate, endure moisture in the extractum with slow fire, reduce to 70 degree from fire again, the second class medicated powder descends first kind medicated powder fully to mix at last and makes obedient cream down.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB031576001A CN1290550C (en) | 2003-09-25 | 2003-09-25 | Chinese medicine composition for treating rheumatism, rheumatoid, hyperosteogeny and fracture and preparing method thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB031576001A CN1290550C (en) | 2003-09-25 | 2003-09-25 | Chinese medicine composition for treating rheumatism, rheumatoid, hyperosteogeny and fracture and preparing method thereof |
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| Publication Number | Publication Date |
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| CN1528386A true CN1528386A (en) | 2004-09-15 |
| CN1290550C CN1290550C (en) | 2006-12-20 |
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| CNB031576001A Expired - Fee Related CN1290550C (en) | 2003-09-25 | 2003-09-25 | Chinese medicine composition for treating rheumatism, rheumatoid, hyperosteogeny and fracture and preparing method thereof |
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Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100368001C (en) * | 2005-05-27 | 2008-02-13 | 王楚清 | Medicine composition for treating rheumatic arthritis and rheumatoid arthritis, and its prepn. method |
| CN101095786B (en) * | 2007-07-02 | 2010-05-19 | 周新民 | Hyperplasia hernia ion rehabilitating ointment and method for preparing the same |
| CN1827137B (en) * | 2005-03-04 | 2010-07-21 | 崔景龙 | Blood-activating bone-resetting capsule |
| CN101543551B (en) * | 2009-04-30 | 2011-04-27 | 王怀顺 | Traditional Chinese medicine plaster for treating wet rheumatism |
| CN1994380B (en) * | 2006-12-25 | 2011-09-28 | 朱帮 | Externally applied medicine for treating arthritis, hot pack and preparation method thereof |
| CN102688473A (en) * | 2012-06-19 | 2012-09-26 | 杨建平 | Externally applied medicine for treating bone fracture and preparation method thereof |
| CN101588810B (en) * | 2007-01-24 | 2012-12-12 | 信一制药株式会社 | Composition comprising trachelospermi caulis and pyrola japonica extracts for the treatment and prevention of inflammatory diseases |
| CN103908642A (en) * | 2014-04-30 | 2014-07-09 | 翟峰 | Drug for treating rheumatic arthralgia and preparation method thereof |
| CN104208635A (en) * | 2014-09-16 | 2014-12-17 | 马昆阳 | Externally used traditional Chinese medicine composition for relieving pain and preparation method thereof |
| CN105343034A (en) * | 2015-10-31 | 2016-02-24 | 韩俊峰 | Black plaster and novel preparation method thereof |
Families Citing this family (1)
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| CN101766729B (en) * | 2010-03-11 | 2011-12-28 | 彭东生 | Damp-clearing pain-relieving liquor and acupoint application treatment method |
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- 2003-09-25 CN CNB031576001A patent/CN1290550C/en not_active Expired - Fee Related
Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1827137B (en) * | 2005-03-04 | 2010-07-21 | 崔景龙 | Blood-activating bone-resetting capsule |
| CN100368001C (en) * | 2005-05-27 | 2008-02-13 | 王楚清 | Medicine composition for treating rheumatic arthritis and rheumatoid arthritis, and its prepn. method |
| CN1994380B (en) * | 2006-12-25 | 2011-09-28 | 朱帮 | Externally applied medicine for treating arthritis, hot pack and preparation method thereof |
| CN101588810B (en) * | 2007-01-24 | 2012-12-12 | 信一制药株式会社 | Composition comprising trachelospermi caulis and pyrola japonica extracts for the treatment and prevention of inflammatory diseases |
| CN101095786B (en) * | 2007-07-02 | 2010-05-19 | 周新民 | Hyperplasia hernia ion rehabilitating ointment and method for preparing the same |
| CN101543551B (en) * | 2009-04-30 | 2011-04-27 | 王怀顺 | Traditional Chinese medicine plaster for treating wet rheumatism |
| CN102688473A (en) * | 2012-06-19 | 2012-09-26 | 杨建平 | Externally applied medicine for treating bone fracture and preparation method thereof |
| CN103908642A (en) * | 2014-04-30 | 2014-07-09 | 翟峰 | Drug for treating rheumatic arthralgia and preparation method thereof |
| CN103908642B (en) * | 2014-04-30 | 2016-07-06 | 吴乐霞 | A kind of medicine treating cold rheumatoid joint pain and preparation method thereof |
| CN104208635A (en) * | 2014-09-16 | 2014-12-17 | 马昆阳 | Externally used traditional Chinese medicine composition for relieving pain and preparation method thereof |
| CN105343034A (en) * | 2015-10-31 | 2016-02-24 | 韩俊峰 | Black plaster and novel preparation method thereof |
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|---|---|
| CN1290550C (en) | 2006-12-20 |
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