CN102688473A

CN102688473A - Externally applied medicine for treating bone fracture and preparation method thereof

Info

Publication number: CN102688473A
Application number: CN2012102029607A
Authority: CN
Inventors: 杨建平
Original assignee: Individual
Current assignee: Individual
Priority date: 2012-06-19
Filing date: 2012-06-19
Publication date: 2012-09-26

Abstract

The invention relates to the field of Chinese medicinal herb, and in particular relates to an externally applied medicine for treating bone fracture, which is prepared by taking the traditional Chinese medicines as crude drugs. The medicine consists of venenum bufonis, radices lithospermi, borneol, black pepper, radix clematidis, calamus, monkshood, cortex acanthopanacis, cinnamon, Chinese angelica, radix aconiti kusnezoffii, pawpaw, pepper, galangal, ginger, stigma croci, frankincense, myrrh, garden balsam stem and hot pepper. The preparation method of the medicine comprises the following steps of: adding the black pepper, the pepper, the ginger and the hot pepper into water, wherein the weight of the water is as heavy as 10-15 times as that of the black pepper, the pepper, the ginger and the hot pepper, filtering, concentrating the filter liquor till that each milliliter of the filter liquor contains 0.2-0.5g of crude drug-containing concentrated liquor, adding medicinal alcohol into the concentrated liquor according to the volume ratio that concentrated liquor: alcohol=(2-3): 1, adding the other crude drugs in parts by weight, soaking for two weeks in a sealing way, filtering, and sterilizing. The medicine has the effects of removing heat to cool blood, activating the blood and detoxifying, clearing heat and stopping pain, warming the meridians, and regulating qi and activating blood, and is effective in the treatment of the bone fracture.

Description

A kind of medicine for external use of treating fracture and preparation method thereof

Technical field

The present invention relates to field of Chinese herbal, especially relating to a kind of is the medicine for external use of the treatment fracture of crude drug preparation with Chinese medicine.

Background technology

Fracture is a kind of accidental injury disease of human body limb, and the fracture at any position all possibly brought influence to whole body, the quality of whole body situation; Also can influence the healing of fracture, must fix, the partial activity of restriction fracture in order to keep the tram of fracture site after reduction; And the activity of limbs comprises joint and muscular movement that knochenbruch reduction position is contiguous, is again to keep limb function, promotes whole body circulation; Ginkgo Biloba, therefore the key factor of accelerating union of bone fracture must appropriately handle fracture fixation (quiet) and the contradiction of hindering limb early stage (moving); Promptly to use suitable local external fixation, also will pay attention to hindering the early ambulant and the functional exercise of limb according to different fracture characteristics; Motion in quiescence, disorder of internal organs has quiet, is association of activity and inertia; Promote fracture local blood circulation and metabolism, stimulate for simultaneously fracture end with gentleness, make Oesteoblast growth active.At present, doctor trained in Western medicine adopts transfusion to add anti-inflammation class Drug therapy more, and integration resets, and mainly leans on self-recovery, conservative treatment, and severe patient is taked operative treatment, brings the hardship of broadsword play and burden economically to patient.

Summary of the invention

The purpose of this invention is to provide a kind of is the medicine for external use of the treatment fracture of crude drug preparation with Chinese medicine, and this medicine is with blood circulation promoting and blood stasis dispelling, and reducing swelling and alleviating pain, liver and kidney tonifying, reunion of bone, eliminating blood stasis to promote regeneration of blood are the principle treatment, and therapeutic effect is good, and expense is low.

Medicine of the present invention is that crude drug prepares by following parts by weight of traditional Chinese medicines:

Venenum Bufonis 3～6 Radix Arnebiae (Radix Lithospermi)s 6～9 Borneolum Syntheticums 10～13

Fructus Piperis 9～11 Radix Clematidis 6～9 Rhizoma Acori Gramineis 6～9

Radix Aconiti 9～11 Cortex Acanthopanciss 9～11 Cortex Cinnamomis 9～11

Radix Angelicae Sinensis 9～11 Radix Aconiti Kusnezoffii 9～11 Fructus Chaenomeliss 9～11

Pericarpium Zanthoxyli 20～30 Rhizoma Alpiniae Officinarum 9～11 Rhizoma Zingiberis Recenss 40～50

Stigma Croci 6～9 Olibanums 9～11 Myrrhas 9～11

Herba speranskiae tuberculatae 15～18 Fructus Capsicis 40～50.

The Fructus Piperis of said parts by weight, Pericarpium Zanthoxyli, Rhizoma Zingiberis Recens, Fructus Capsici are added in the water of its 10-15 times weight and decoct; Filter; Filtrating is concentrated into every milliliter of concentrated solution that contains crude drug 0.2～0.5g, and according to concentrated solution: the volume ratio of ethanol=2～3:1 adds medical alcohol in concentrated solution, add all the other bulk drugs again; In airtight two weeks of immersion, filter, sterilize and process.

In the prescription of the present invention, Venenum Bufonis detoxifcation, pain relieving, the refreshment of having one's ideas straightened out; The Radix Arnebiae (Radix Lithospermi) clearing away heat and cooling blood, promoting blood circulation and detoxication, rash speckle removing; The Borneolum Syntheticum refreshment of having one's ideas straightened out, clearing away heat to alleviate pain; The Fructus Piperis warming spleen and stomach for dispelling cold, the therapeutic method to keep the adverse QI flowing downwards, expectorant; The Radix Clematidis wind-damp dispelling, the meridian dredging, stopping numbness pain; The Rhizoma Acori Graminei inducing resuscitation and resolving phlegm, activating spleen-QI and calming the mind; The Radix Aconiti expelling wind and removing dampness, antalgic; The Cortex Acanthopancis expelling wind and removing dampness, liver and kidney tonifying, bone and muscle strengthening, inducing diuresis to remove edema; It is supporing yang that Cortex Cinnamomi is mended fire, guiding fire to origin, dispersing cold for relieving pain, promoting the flow of QI-blood by warming the meridian; The Radix Angelicae Sinensis detoxifcation, eliminating stagnation, detumescence; Radix Aconiti Kusnezoffii is searched wind prevailing over dampness, and dispersing cold for relieving pain is opened expectorant, detumescence; The Fructus Chaenomelis relaxing muscles and tendons and activating QI and blood in the collateral, the stomach function regulating removing dampness; The Pericarpium Zanthoxyli warming middle-JIAO to relieve pain, killing parasites for relieving itching; Rhizoma Alpiniae Officinarum stomach warming preventing or arresting vomiting, dispersing cold for relieving pain; The Rhizoma Zingiberis Recens cold expelling that induces sweat, warming middle-JIAO to arrest vomiting, preventing phlegm from forming and stopping coughing, solving toxin of fish and crab; The Stigma Croci blood circulation promoting and blood stasis dispelling, removing pathogenic heat from blood and toxic substance from the body, resolving stagnation for tranquilization; The Olibanum regulating qi and activating blood, analgesic therapy chases after poison; The Myrrha promoting flow of QI and blood, subduing swelling and relieving pain; The Herba speranskiae tuberculatae expelling wind and removing dampness, promoting blood circulation and stopping pain; The Fructus Capsici promoting blood circulation and detumescence.All medicines share, and can play clearing away heat and cooling blood, promoting blood circulation and detoxication, and clearing away heat to alleviate pain, promoting the flow of QI-blood by warming the meridian, the effect of regulating qi and activating blood is remarkable to the treatment curative effect of fracture.

For further investigating the clinical efficacy of Drug therapy fracture of the present invention, select 85 routine fracture patient cardinal symptom fracture, the fracture swelling and pain due to blood stasis has carried out clinical observation on the therapeutic effect.

Be divided into treatment group and matched group to 63 routine patients, 40 people are organized in treatment, matched group 45 people.

All case is all according to the diagnostic criteria in " new Chinese medicine clinical research guideline (first volume) ":

The trauma history that direct or indirect violence is arranged.

General Symptoms: uncomplicated simple fracture, General Symptoms are very unobvious or not serious; Serious wound, combined injury can be suffered a shock, or merge visceral organ injury; But the open fracture concurrent infection, or and go crazy, the damage of blood vessel.

Local symptom: pain and tenderness, local swelling, dysfunction, deformity, abnormal movement, bone mill sassafras sound.

The X ray examination: the diagnosis that can clearly fracture, can confirm localized variation such as classification of fracture, direction of displacement, fracture end form, and get rid of pathologisch Bruch.

Therapeutic Method:

Matched group 45 people mainly adopt JIEGU GAO (the Guangdong college of traditional Chinese medicine) by the routine treatment treatment, penicillin, transfusion, conservative treatment treatment.Treatment is organized 40 people and is adopted Drug therapy of the present invention, spreads upon the affected part one day 3 times.Two groups of cases were all treated for 8 weeks continuously, the contrast curative effect.

Curative effect determinate standard:

Effectively: congestion basic disappearance of swelling and ache, fracture are healed for effectively basically.

Recovery from illness: congestion disappearances of swelling and ache, the fracture healing, the affected part activity is not as usual bitterly for fully recovering.

Two groups of case treatment back curative effect comparative results are seen table 1.

Table 1 liang group case treatment back curative effect relatively

Group	The example number	Recovery from illness n (%)	Effective n (%)
				Matched group	45	32（71.1）	13（28.9）
The treatment group	40	38（95.0）	2（5.0）

Clinical test results proves that drug effect of the present invention obviously is superior to matched group, does not see any untoward reaction.

The specific embodiment

Embodiment 1

Get Venenum Bufonis 3 kg, Radix Arnebiae (Radix Lithospermi) 6 kg, Borneolum Syntheticum 10 kg, Fructus Piperis 9 kg, Radix Clematidis 6 kg, Rhizoma Acori Graminei 6 kg; Radix Aconiti 9 kg, Cortex Acanthopancis 9 kg, Cortex Cinnamomi 9 kg, Radix Angelicae Sinensis 9 kg, Radix Aconiti Kusnezoffii 9 kg, Fructus Chaenomelis 9 kg; Pericarpium Zanthoxyli 20 kg, Rhizoma Alpiniae Officinarum 9 kg, Rhizoma Zingiberis Recens 40 kg, Stigma Croci 6 kg, Olibanum 9 kg; Myrrha 9 kg, Herba speranskiae tuberculatae 15 kg, Fructus Capsici 40 kg add water 1500kg with the Fructus Piperis in the above-mentioned raw materials medicine, Pericarpium Zanthoxyli, Rhizoma Zingiberis Recens, Fructus Capsici and decoct, and filter; Filtrating is concentrated into every milliliter of concentrated solution that contains crude drug 0.3g, in concentrated solution, adds medical alcohol according to the volume ratio of concentrated solution: ethanol=2:1, adds all the other bulk drugs again, in airtight two weeks of immersion, filters, sterilization processes.

Embodiment 2

Get Venenum Bufonis 6 kg, Radix Arnebiae (Radix Lithospermi) 9 kg, Borneolum Syntheticum 13 kg, Fructus Piperis 11 kg, Radix Clematidis 9 kg; Rhizoma Acori Graminei 9 kg, Radix Aconiti 11 kg, Cortex Acanthopancis 11 kg, Cortex Cinnamomi 11 kg, Radix Angelicae Sinensis 11 kg; Radix Aconiti Kusnezoffii 11 kg, Fructus Chaenomelis 11 kg, Pericarpium Zanthoxyli 30 kg, Rhizoma Alpiniae Officinarum 11 kg, Rhizoma Zingiberis Recens 50 kg; Stigma Croci 9 kg, Olibanum 11 kg, Myrrha 11 kg, Herba speranskiae tuberculatae 18 kg; Fructus Capsici 50 kg add water 1500 kg with the Fructus Piperis in the above-mentioned raw materials medicine, Pericarpium Zanthoxyli, Rhizoma Zingiberis Recens, Fructus Capsici and decoct, and filter, and filtrating is concentrated into every milliliter of concentrated solution that contains crude drug 0..5g; Volume ratio according to concentrated solution: ethanol=2:1 adds medical alcohol in concentrated solution, add all the other bulk drugs again, in airtight two weeks of immersion, filters, sterilizes and process.

Claims

1. medicine for external use of treating fracture is that crude drug prepares by following parts by weight of traditional Chinese medicines:

Fructus Piperis 9～11 Radix Clematidis 6～9 Rhizoma Acori Gramineis 6～9

Radix Aconiti 9～11 Cortex Acanthopanciss 9～11 Cortex Cinnamomis 9～11

Stigma Croci 6～9 Olibanums 9～11 Myrrhas 9～11

Herba speranskiae tuberculatae 15～18 Fructus Capsicis 40～50.

2. the medicine for external use that said treatment is fractured according to claim 1; Its preparation method is: decoct in the water with the Fructus Piperis in the said crude drug, Pericarpium Zanthoxyli, Rhizoma Zingiberis Recens, its 10-15 of Fructus Capsici adding times weight, filter, filtrating is concentrated into every milliliter of concentrated solution that contains crude drug 0.2～0.5g; According to concentrated solution: the volume ratio of ethanol=2～3:1 adds medical alcohol in concentrated solution; Add all the other bulk drugs again, in airtight two weeks of immersion, filter, sterilize and process.