CN1899387B - Method for preventing and treating child convulsion and its preparing method - Google Patents

Method for preventing and treating child convulsion and its preparing method Download PDF

Info

Publication number
CN1899387B
CN1899387B CN200610019595A CN200610019595A CN1899387B CN 1899387 B CN1899387 B CN 1899387B CN 200610019595 A CN200610019595 A CN 200610019595A CN 200610019595 A CN200610019595 A CN 200610019595A CN 1899387 B CN1899387 B CN 1899387B
Authority
CN
China
Prior art keywords
medicine
radix
infantile convulsion
rhizoma rhei
cow
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN200610019595A
Other languages
Chinese (zh)
Other versions
CN1899387A (en
Inventor
刘久良
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CN200610019595A priority Critical patent/CN1899387B/en
Publication of CN1899387A publication Critical patent/CN1899387A/en
Application granted granted Critical
Publication of CN1899387B publication Critical patent/CN1899387B/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Abstract

The present invention relates to a kind of medicine for preventing and treating infant convulsion and its preparation process. The medicine is prepared with pharbitis 4-8 weight portions and rhubarb 4-8 weight portions. The preparation process includes frying pharbitis; soaking rhubarb in spirit for 3-10 min, steaming for 3-10 min and drying in sunlight; mixing and crushing. The medicine has the functions of dispelling wind, clearing away fire, promoting resuscitation, etc. and possesses high effect of preventing and treating infant convulsion and no toxic side effect.

Description

Medicine of control infantile convulsion and preparation method thereof
Technical field:
The present invention relates to a kind of medicine of preventing and treating infantile convulsion and preparation method thereof.
Background technology:
Infantile convulsion is the symptom of infantile convulsion disease.The infantile convulsion disease is divided into acute infantile convulsion and chronic infantile convulsion, sees it is acute infantile convulsion clinically more.Acute infantile convulsion: the oncoming force is anxious sudden and violent, but before convulsive attack, heating is often arranged, vomiting, agitation, the frequent protrusion of the tongue of shaking the head.The time send out night crying due to fright in infant or the premonitory symptom such as drowsiness of going into a coma, but for the time of short duration or be difficult for discovering.The primary symptom characteristics are health heating, accumulation and obstruction of sputum, spasm of the limbs during morbidity, and the muscle arteries and veins is held up, and stiffness of the nape and back is looked on the order eyeball, and mandibular joint is urgent, the lip parch, and the stupor of twitching, normal expectorant, heat, frightened, wind, four diseases also go out.
All can take place any season, generally with the children's in 1-5 year for seeing more, have 3 percent to five heating children's can send out this disease, the age is more little, sickness rate is high more.
Its disease feelings are often more dangerous, change rapidly, threaten children's's life.So ancient medicine thinks that infantile convulsion is that a kind of evil is waited.Say as " Dong-eui-bo-gam children's ": the danger person of children's's disease, do not have the card of infantile convulsion more." pediatrics is released the mystery infantile convulsion " also said: children's's disease, the heaviest thought is frightened.But in existing Chinese medicine or the Western medicine, the control medicine of needleless convulsions symptom that children's is caused because of heating still causes children's in case heating will produce the convulsions symptom so far.The infantile convulsion disease is to produce developing infantile intelligence to grow one of main killer who descends with dead.
Summary of the invention:
The object of the present invention is to provide and a kind ofly can prevent and treat medicine of infantile convulsion and preparation method thereof, this chemoprophylaxis and treatment infantile convulsion respond well, have no side effect, medicament sources is extensive.
Technical scheme of the present invention is as follows:
1, the medicine of control infantile convulsion: it comprises that following raw materials according makes the 4-8 part of leading a cow, Radix Et Rhizoma Rhei 4-8 part.
2, the preparation method of the medicine of control infantile convulsion:
1. the 4-8 part of will leading a cow was earlier fried, but can not parching to brown, and general stir-fry gets final product to exploding later;
2. Radix Et Rhizoma Rhei 4-8 part was steeped 3-10 minute with steeping in wine, last cage boils and steamed 3-10 minute, and the time of steaming is oversize, and drug effect can reduce, and therefore the time of steaming is unsuitable oversize.
3. above-mentioned two flavor medicines are dried, mix or the mixing of pulverizing back.
Pharmaceutical formulation of the present invention be have eight more than ten years history secret prescription handed down in the family from generation to generation, it has following advantage: dispelling wind relieves inflammation or internal heat, have one's ideas straightened out, it is relieving convulsion to relieve dizziness, high fever, infantile convulsions, epilepsy, etc., removing pathogenic heat from blood and toxic substance from the body, the clearing away phlegm spasmolytic, respond well, the cure rate of this chemoprophylaxis and treatment infantile convulsion reach more than 95%, have no side effect, medicament sources is extensive.
The specific embodiment:
One, the present invention's medicine of preventing and treating infantile convulsion has following four assembly sides (weight fraction of all raw materials of the present invention than the weight fraction that is fresh feed than)
1. lead a cow 4-8 part, Radix Et Rhizoma Rhei 4-8 part, Rhizoma Chuanxiong 2-5 part, Radix Scutellariae 2-5 part, Cortex Phellodendri 2-5 part.
2. lead a cow 4-8 part, Radix Et Rhizoma Rhei 4-8 part, Herba Menthae 3-6 part, Fructus Forsythiae 2-5 part or add Cornu Saigae Tataricae powder 0.3-1 part again.
3. lead a cow 4-8 part, Radix Et Rhizoma Rhei 4-8 part, Rhizoma Chuanxiong 2-5 part, Radix Scutellariae 2-5 part, Cortex Phellodendri 2-5 part, Herba Menthae 2-4 part, Fructus Forsythiae 2-5 part.
4. lead a cow 4-8 part, Radix Et Rhizoma Rhei 4-8 part, Rhizoma Chuanxiong 2-5 part, Radix Scutellariae 2-5 part, Cortex Phellodendri 2-5 part, Herba Menthae 2-4 part, Fructus Forsythiae 2-5 part, Cornu Saigae Tataricae powder 0.3-1 part.
In above-mentioned four kinds of prescriptions, be the best with the 4th kind.
Two, the preparation method of the medicine of control infantile convulsion:
1. will lead a cow earlier and fry, but can not parching to brown, general stir-fry gets final product to exploding later;
2. Radix Et Rhizoma Rhei part was soaked 3-10 minute fully with wine, last cage boils and steamed 3-10 minute, and the time of steaming is oversize, and drug effect can reduce, and therefore the time of steaming does not declare oversize; The Radix Et Rhizoma Rhei that steamed is dried.
3. after Radix Scutellariae, Cortex Phellodendri being soaked 3-10 minute fully with wine, put into the pot parching to brown, but parching to brown does not get final product; Further dry again.
Leading a cow after 4. will handling through above-mentioned steps, Radix Et Rhizoma Rhei, Radix Scutellariae, Cortex Phellodendri are mixed the shape of claying into power with dried Rhizoma Chuanxiong; The remix of perhaps they being clayed into power respectively behind the shape is even, promptly gets medicine of the present invention.
Perhaps, leading a cow after will handling through above-mentioned steps, Radix Et Rhizoma Rhei be with after dried Herba Menthae, Fructus Forsythiae mixes, the shape of claying into power, and remix is even behind the shape of perhaps they being clayed into power respectively, and then with Cornu Saigae Tataricae powder mix homogeneously with it, promptly gets medicine of the present invention.
Perhaps, leading a cow after will handling through above-mentioned steps, Radix Et Rhizoma Rhei, Rhizoma Chuanxiong, Radix Scutellariae, Cortex Phellodendri and the shape of claying into power after dried Herba Menthae, Fructus Forsythiae mixes, remix is even behind the shape of perhaps they being clayed into power respectively, promptly gets medicine of the present invention.
Perhaps, leading a cow after handling through above-mentioned steps, Radix Et Rhizoma Rhei, Radix Scutellariae, Cortex Phellodendri and the shape of claying into power after dried Rhizoma Chuanxiong, Herba Menthae, Fructus Forsythiae mixes, the remix of perhaps they being clayed into power respectively behind the shape is even, and then with Cornu Saigae Tataricae powder mix homogeneously with it, promptly gets medicine of the present invention.
5. can be ball with the Mel refining with step powdery medicine 5-10g 4., the addition of Mel be that ball gets final product above-mentioned steps powdery medicine 4. can be glued.
Instructions of taking:
Directly the medicine of the present invention that 4. step is made adds water and stewes the back extracting juice, divides and takes for three to five times.For the infant in 1-2 year, according to the dosage of 20 grams every day, add 200ml water and stew the back extracting juice, divide and take for three to five times.For the infant in 3-4 year, according to the dosage of 30 grams every day, add 300ml water and stew the back extracting juice, divide and take for three to five times.For the infant in 5-6 year, according to the dosage of 35 grams every day, add 350ml water and stew the back extracting juice, divide and take for three to five times.
To can supply the child administration more than 6 years old through the 5. sweet pill that refines of step.Each ball, twice on the one.
Embodiment 1:
1. will lead a cow earlier 4 parts and fry, but can not parching to brown, general stir-fry gets final product to exploding later;
2. 4 parts of Radix Et Rhizoma Rhei were soaked 3 minutes fully with wine, last cage boils and steamed 10 minutes; The Radix Et Rhizoma Rhei that steamed is dried.
3. after 5 parts of 5 parts of Radix Scutellariaes, Cortex Phellodendri being soaked 10 minutes fully with wine, put into the pot parching to brown, but parching to brown does not get final product; Further dry again.
Leading a cow after 4. will drying, Radix Et Rhizoma Rhei, Radix Scutellariae, Cortex Phellodendri mix after doing with 5 parts of Rhizoma Chuanxiongs, 6 portions of Herba Menthaes, 5 parts of Fructus Forsythiaes, the shape of claying into power then, the remix of perhaps they being clayed into power respectively behind the shape is even, and then with 1 part of Cornu Saigae Tataricae powder mix homogeneously with it, promptly gets medicine of the present invention.
Embodiment 2:
1. will lead a cow earlier 8 parts and fry, but can not parching to brown, general stir-fry gets final product to exploding later;
2. 8 parts of Radix Et Rhizoma Rhei were soaked 6 minutes fully with wine, last cage boils and steamed 5 minutes; The Radix Et Rhizoma Rhei that steamed is dried.
3. after 2 parts of 2 parts of Radix Scutellariaes, Cortex Phellodendri being soaked 3 minutes fully with wine, put into the pot parching to brown, but parching to brown does not get final product; Further dry again.
4. the shape of claying into power after mixing with leading a cow after above-mentioned the drying, Radix Et Rhizoma Rhei, Radix Scutellariae, Cortex Phellodendri and after 3 parts of Rhizoma Chuanxiongs are done, remix is even behind the shape of perhaps they being clayed into power respectively, promptly gets medicine of the present invention.
5. can be ball with the Mel refining with step powdery medicine 8g 4., the addition of Mel be that ball gets final product above-mentioned steps powdery medicine 4. can be glued.Obtain medicine of the present invention thus.
Embodiment 3:
1. will lead a cow earlier 6 parts and fry, but can not parching to brown, general stir-fry gets final product to exploding later;
2. 6 parts of Radix Et Rhizoma Rhei were soaked 10 minutes fully with wine, last cage boils and steamed 3 minutes; The Radix Et Rhizoma Rhei that steamed is dried.
3. will through leading a cow of handling of above-mentioned steps, Radix Et Rhizoma Rhei and 4 portions of Herba Menthaes, 4 parts of Fructus Forsythiaes dried mix after the shape of claying into power, remix is even behind the shape of perhaps they being clayed into power respectively, and then with 0.3 part of Cornu Saigae Tataricae powder mix homogeneously with it;
4. can be ball with the Mel refining with step powdery medicine 6g 4., the addition of Mel be that ball gets final product above-mentioned steps powdery medicine 4. can be glued.Obtain medicine of the present invention thus.
Embodiment 4:
1. will lead a cow earlier 4 parts and fry, but can not parching to brown, general stir-fry gets final product to exploding later;
2. 4 parts of Radix Et Rhizoma Rhei were soaked 5 minutes fully with wine, last cage boils and steamed 5 minutes; The Radix Et Rhizoma Rhei that steamed is dried.
3. after 3 parts of 3 parts of Radix Scutellariaes, Cortex Phellodendri being soaked 5 minutes fully with wine, put into the pot parching to brown, but parching to brown does not get final product; Further dry again.
Leading a cow after 4. will drying, Radix Et Rhizoma Rhei, Radix Scutellariae, Cortex Phellodendri mix after doing with 3 parts of Rhizoma Chuanxiongs, 2 portions of Herba Menthaes, 3 parts of Fructus Forsythiaes, the shape of claying into power then, the remix of perhaps they being clayed into power respectively behind the shape is even, and then with 0.5 Cornu Saigae Tataricae powder mix homogeneously with it, promptly gets medicine of the present invention.
It is as follows that medicine of the present invention is used for the case and the therapeutic effect of infantile convulsion treatment:
Case 1:
3 years old Ningde City gold of patient Zheng Xiaodi man contained village people father and mother's phone 13159355219
38.7 ℃ of body temperature of heating, agitation, brothers twitch repeatedly, and stiffness of the neck is looked on the order eyeball, and with vomiting, the pimple sample appears in whole skin scratches where it itches, cough, constipation, yellow fur rapid pulse and strong.
Medical history: existing five days of morbidity hospitalization, body temperature does not fall, and twitches tentative diagnosis every day repeatedly three to five times: doubt epidemic encephalitis.
Obeyed in the medicine of the present invention a day, agitation, brothers twitch repeatedly, and stiffness of the neck symptom such as is looked and is not reaccessed on the order eyeball, left hospital in second day to come here to continue to take medicine to consolidate two days.Just recurred never again the treatment back.
Case 2:
4 years old Ningde City Zhang Wan town back bay people from village father and mother phone 0593-2268636 of the little younger sister woman of patient Lee
40.5 ℃ of body temperature of heating, fidgety, tetany suddenly, stiffness of the neck is looked on the eyes, with vomiting, coma, halitosis, dry and yellow fur, rapid pulse and strong.
Medical history: six monthly ages begin the infantile convulsion disease falls ill repeatedly repeatedly, whenever heating body temperature just recurs above disease more than 39 ℃, also repeatedly be in hospital, but the recurrence of infantile convulsion disease all fails to eradicate.Existing four morbidities in nearly two months, four times in hospital, school's trial inspection diagnosis: doubt meningitis.
After having obeyed medicine of the present invention handed down from one's ancestors, had a surplus in three months so far,, do not see that a series of symptoms of infantile convulsion occur though three heating body temperature are arranged all at 40 ℃.
Case 3:
The patient swims 4 years old right 5 lanes No. 18 father and mother's phones 0593-2869087 in Ningde City children's palace of youngest brother man
Suddenly hyperpyrexia body temperature is 41 ℃, irritated delirium, and coma is twitched repeatedly, and stiffness of the neck is looked on the eyes, gnathospasma, lip parch, constipation, yellowish or reddish urine, yellowish fur, slippery and rapid pulse.
Medical history: surplus the similar conditions existing ten that year old shows effect repeatedly age to four in infant one week time, each examination in hospital cause of disease has no resolution.
Obeyed behind the medicine of the present invention to nowadays more than 2 years, the head of a family informs and does not just reaccess at the back of taking medicine this is not out of shape.
Case 4:
Private garden people father and mother phone 13850350571 under two years old Ningde City of the old little younger sister woman of patient
About 38 ℃ just outbreak convulsions of each fever, outbreak has been fainted from fear six times repeatedly, and the examination in hospital cause of disease has no resolution.Obeyed behind the medicine of the present invention so far more than a year, though there is several times fever not see convulsive attack.
Case 5:
Patient: youngest brother Peng, 4 years old Ningde City Zhang Wan south of a town field of razor clam people from village father and mother phone 13860392853 of man
About 38 ℃ just outbreak convulsions of each fever, outbreak has been fainted from fear repeatedly repeatedly, and the examination in hospital cause of disease has no resolution.Obeyed behind the medicine of the present invention so far more than 2 years, though there is several times fever not see convulsive attack.
Clinical drug of the present invention is cured the convulsions infant and is observed: be total to case 128 examples, 40 examples that heating is fainted from fear more than 39 ℃, 84 examples of about the 38 ℃ convulsions of generating heat, several monthly ages to six at infant age are year old in the majority, only account for several examples more than six years old, all cases are all got rid of epilepsy, hypoglycemia, low blood calcium, tetanus, nervus centralis disease through examination in hospital.Cure in the 124 routine convulsions infants, heating is fainted from fear at every turn, and what the twice above prevention that show effect repeatedly showed effect once more accounts for 80%.That cures during convulsive attack accounts for 20% as (youngest brother's Zheng the state of an illness), and none the routine infant of back of taking medicine convulsionss of showing effect is is once more prevented and treated the convulsive attack rate and reached more than 95%.2 routine infant hyperpyrexia convulsion can not get timely treatment, cause the sequela of dysnoesia.2 routine infants are epilepticss in addition, and therapeutic effect is undesirable.

Claims (5)

1. medicine of preventing and treating infantile convulsion, it is characterized in that: it is made by following ratio of weight and number raw material, the 4-8 part of leading a cow, Radix Et Rhizoma Rhei 4-8 part, Herba Menthae 3-6 part, Fructus Forsythiae 2-5 part.
2. the medicine of control infantile convulsion according to claim 1 is characterized in that: also add Cornu Saigae Tataricae powder 0.3-1 part.
3. the medicine of control infantile convulsion according to claim 1 is characterized in that: also add Rhizoma Chuanxiong 2-5 part, Radix Scutellariae 2-5 part, Cortex Phellodendri 2-5 part.
4. the medicine of control infantile convulsion according to claim 1 is characterized in that: also add Rhizoma Chuanxiong 2-5 part, Radix Scutellariae 2-5 part, Cortex Phellodendri 2-5 part, Cornu Saigae Tataricae powder 0.3-1 part.
5. the preparation method of control infantile convulsion medicine according to claim 4 is characterized in that its preparation methods steps is as follows:
1. will lead a cow earlier and fry, but can not parching to brown, general stir-fry gets final product to exploding later;
2. Radix Et Rhizoma Rhei was soaked 3-10 minute fully with wine, last cage boils and steamed 3-10 minute, and the time of steaming is oversize, and drug effect can reduce, and therefore the time of steaming is unsuitable oversize; The Radix Et Rhizoma Rhei that steamed is dried;
3. after Radix Scutellariae, Cortex Phellodendri being soaked 3-10 minute fully with wine, put into the pot parching to brown, but parching to brown does not get final product; Further dry again;
Leading a cow after 4. will handling, Radix Et Rhizoma Rhei, Radix Scutellariae, Cortex Phellodendri and the shape of claying into power after dried Rhizoma Chuanxiong, Herba Menthae, Fructus Forsythiae mixes through above-mentioned steps, remix is even behind the shape of perhaps they being clayed into power respectively, and then with Cornu Saigae Tataricae powder mix homogeneously with it, promptly;
5. be ball with step powdery medicine 5-10g 4. with the Mel refining, the addition of Mel is that ball gets final product above-mentioned steps powdery medicine 4. can be glued.
CN200610019595A 2006-07-08 2006-07-08 Method for preventing and treating child convulsion and its preparing method Expired - Fee Related CN1899387B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN200610019595A CN1899387B (en) 2006-07-08 2006-07-08 Method for preventing and treating child convulsion and its preparing method

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN200610019595A CN1899387B (en) 2006-07-08 2006-07-08 Method for preventing and treating child convulsion and its preparing method

Publications (2)

Publication Number Publication Date
CN1899387A CN1899387A (en) 2007-01-24
CN1899387B true CN1899387B (en) 2010-05-12

Family

ID=37655497

Family Applications (1)

Application Number Title Priority Date Filing Date
CN200610019595A Expired - Fee Related CN1899387B (en) 2006-07-08 2006-07-08 Method for preventing and treating child convulsion and its preparing method

Country Status (1)

Country Link
CN (1) CN1899387B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103230460B (en) * 2013-04-23 2015-03-25 彭连志 Medicine for treating manic-depressive psychosis and preparation method thereof
CN103239640A (en) * 2013-05-15 2013-08-14 王晓霞 Traditional Chinese medicine granule for treating infantile convulsion and preparation method thereof
CN104524271A (en) * 2014-12-18 2015-04-22 郝贵华 Liver wind calming preparation for treating acute infantile convulsion and preparation method thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1785340A (en) * 2005-07-28 2006-06-14 江西汇仁药业有限公司 Compound bovine bezoar stomach clearing fast dispersion solid preparation and its preparation method

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1785340A (en) * 2005-07-28 2006-06-14 江西汇仁药业有限公司 Compound bovine bezoar stomach clearing fast dispersion solid preparation and its preparation method

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
李晏龄.儿科常用中药散剂介绍.中国临床医生 10.1979,(10),31.
李晏龄.儿科常用中药散剂介绍.中国临床医生 10.1979,(10),31. *
马荫笃.儿科散剂及其临床应用.上海中医药杂志 9.1981,(9),11-13.
马荫笃.儿科散剂及其临床应用.上海中医药杂志 9.1981,(9),11-13. *

Also Published As

Publication number Publication date
CN1899387A (en) 2007-01-24

Similar Documents

Publication Publication Date Title
KR102121153B1 (en) Dietary herbal composition, dietary herbal medicine pill comprising the same and method for manufacturing thereof
CN101077403A (en) Plaster for treating retention of food and dysmenorrhea
CN102293900B (en) Chinese medicine for treating infantile diarrhea
CN1868535A (en) Medicine composition for treating rheumatic arthritis and rheumatoid arthritis, and its prepn. method
CN105707384A (en) Lumbricus protein composite tablet candy and preparation method thereof
CN1899387B (en) Method for preventing and treating child convulsion and its preparing method
CN1290550C (en) Chinese medicine composition for treating rheumatism, rheumatoid, hyperosteogeny and fracture and preparing method thereof
CN1247231C (en) Health care medicine for enriching blood in puerperium and its preparation and uses
CN104147196A (en) Medicine for treating children recurrent oral ulceration and preparation method thereof
CN104435319B (en) A kind of herbal medicine for preventing piglet stress reaction
CN101564433B (en) Chinese medicinal composition for treating rheumatic diseases, and preparation method thereof
CN104784495A (en) Traditional Chinese medicine preparation for treating infantile convulsion and preparation method
CN1186056C (en) Medicine for treating osteoproliferation
CN100358552C (en) Medicine for treating amblyopia and its preparing method
CN103191310A (en) Medicament for treating vacuity-cold-type epigastric pain
CN103933277A (en) Tibetan drug for treating gout disease
CN102813888A (en) Chinese herbal composition for treating epilepsy
CN107913389A (en) A kind of Chinese medicine composition for treating Thyroid Gland Swell and preparation method thereof
CN101983712A (en) Novel medicament for treating coronary heart disease
CN110420309B (en) Anti-inflammatory analgesic Tibetan medicine pill for treating chronic appendicitis
CN104523866A (en) Convulsion and spasm relieving preparation for treating infantile febrile convulsion and preparation method thereof
CN1907315A (en) Orthopaedics disease treating and preventing medicinal composition
CN104498297A (en) Health wine containing spider sloughs and preparation method thereof
CN104306585A (en) Traditional Chinese medicine combination for curing prostatitis, and preparation method and application thereof
CN103933278A (en) Preparation method of Tibetan drug for treating gout disease

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20100512

Termination date: 20140708

EXPY Termination of patent right or utility model