CN1527722A - 天花疫苗 - Google Patents

天花疫苗 Download PDF

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Publication number
CN1527722A
CN1527722A CNA028126335A CN02812633A CN1527722A CN 1527722 A CN1527722 A CN 1527722A CN A028126335 A CNA028126335 A CN A028126335A CN 02812633 A CN02812633 A CN 02812633A CN 1527722 A CN1527722 A CN 1527722A
Authority
CN
China
Prior art keywords
vaccinia virus
strain
dryvax
virus
clone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA028126335A
Other languages
English (en)
Chinese (zh)
Inventor
R��A������
R·A·韦尔钦
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T·P·莫纳斯
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Pasteur Biologics LLC
Original Assignee
Acambis Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Acambis Inc filed Critical Acambis Inc
Publication of CN1527722A publication Critical patent/CN1527722A/zh
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/275—Poxviridae, e.g. avipoxvirus
    • A61K39/285—Vaccinia virus or variola virus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5254—Virus avirulent or attenuated
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/24011—Poxviridae
    • C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
    • C12N2710/24161—Methods of inactivation or attenuation

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Biotechnology (AREA)
  • Communicable Diseases (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CNA028126335A 2001-04-23 2002-04-23 天花疫苗 Pending CN1527722A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/840,751 US6723325B1 (en) 2001-04-23 2001-04-23 Smallpox vaccine
US09/840,751 2001-04-23

Publications (1)

Publication Number Publication Date
CN1527722A true CN1527722A (zh) 2004-09-08

Family

ID=25283120

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA028126335A Pending CN1527722A (zh) 2001-04-23 2002-04-23 天花疫苗

Country Status (19)

Country Link
US (2) US6723325B1 (https=)
EP (1) EP1381389B1 (https=)
JP (1) JP4397591B2 (https=)
KR (1) KR20040063083A (https=)
CN (1) CN1527722A (https=)
AU (1) AU2002258910B2 (https=)
BR (1) BR0209145A (https=)
CA (1) CA2444747C (https=)
CZ (1) CZ305819B6 (https=)
EA (1) EA007656B1 (https=)
ES (1) ES2546612T3 (https=)
HU (1) HU228401B1 (https=)
IL (2) IL158549A0 (https=)
MA (1) MA26270A1 (https=)
MX (1) MXPA03009711A (https=)
NZ (1) NZ529265A (https=)
PL (1) PL212117B1 (https=)
WO (1) WO2002085411A1 (https=)
ZA (1) ZA200309084B (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114262690A (zh) * 2011-04-15 2022-04-01 吉恩勒克斯公司 减毒的痘苗病毒的克隆毒株及其使用方法

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7645456B2 (en) * 2001-04-23 2010-01-12 Sanofi Pasteur Biologics Co. Vaccinia virus strains
US6723325B1 (en) * 2001-04-23 2004-04-20 Acambis, Inc. Smallpox vaccine
US20090269365A1 (en) * 2005-04-20 2009-10-29 University Of Washington Immunogenic vaccinia peptides and methods of using same
MX2009004862A (es) 2006-11-07 2009-07-17 Sanofi Pasteur Biologics Co Estabilizacion de vacunas por liofilizacion.
KR100859345B1 (ko) * 2006-12-12 2008-09-19 씨제이제일제당 (주) 세포배양에 의해 두창 백신을 생산하는 방법 및 그에 의해생산된 두창 백신
RU2496149C1 (ru) * 2012-06-19 2013-10-20 Федеральное бюджетное учреждение науки "Государственный научный центр вирусологии и биотехнологии "Вектор" (ФБУН ГНЦ ВБ "Вектор") Способ оценки противооспенной активности лечебно-профилактических препаратов
JP2019535311A (ja) 2016-11-02 2019-12-12 デイビッド エバンス， 合成キメラポックスウイルス
EP3788142A4 (en) 2018-05-02 2022-04-27 Tonix Pharma Holdings Limited SYNTHETIC CHIMERIC VACCINE VIRUS
US11505782B2 (en) 2018-06-04 2022-11-22 Calidi Biotherapeutics, Inc. Cell-based vehicles for potentiation of viral therapy
CA3116192C (en) 2018-11-06 2025-09-23 Calidi Biotherapeutics (Nevada), Inc. IMPROVED SYSTEMS FOR CELL-MEDIATED ONCOLYTIC VIRAL THERAPY
WO2025184411A1 (en) 2024-02-27 2025-09-04 Calidi Biotherapeutics (Nevada), Inc. Serum-resistant eev viruses and uses thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4315914A (en) * 1980-04-04 1982-02-16 Seiji Arakawa Pharmaceutical compositions useful as cellular immunopotentiator and antitumor agent and process for production thereof
JPS60202827A (ja) 1984-03-28 1985-10-14 Chibaken 弱毒痘そうワクチン株
US5614193A (en) * 1991-11-14 1997-03-25 The United States Of America As Represented By The Secretary Of The Army Hantavirus vaccine
US5656465A (en) * 1994-05-04 1997-08-12 Therion Biologics Corporation Methods of in vivo gene delivery
US6723325B1 (en) 2001-04-23 2004-04-20 Acambis, Inc. Smallpox vaccine

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114262690A (zh) * 2011-04-15 2022-04-01 吉恩勒克斯公司 减毒的痘苗病毒的克隆毒株及其使用方法
US12338464B2 (en) 2011-04-15 2025-06-24 Genelux Corporation Clonal strains of attenuated vaccinia viruses and methods of use thereof

Also Published As

Publication number Publication date
US7115270B2 (en) 2006-10-03
JP4397591B2 (ja) 2010-01-13
EP1381389A1 (en) 2004-01-21
HUP0303878A3 (en) 2010-01-28
ES2546612T3 (es) 2015-09-25
KR20040063083A (ko) 2004-07-12
WO2002085411A1 (en) 2002-10-31
MXPA03009711A (es) 2005-03-07
US6723325B1 (en) 2004-04-20
PL373958A1 (en) 2005-09-19
AU2002258910B2 (en) 2007-10-25
EP1381389B1 (en) 2015-08-26
CA2444747A1 (en) 2002-10-31
US20060153873A1 (en) 2006-07-13
CZ20033184A3 (cs) 2004-04-14
ZA200309084B (en) 2005-01-26
HU228401B1 (en) 2013-03-28
CA2444747C (en) 2018-04-17
PL212117B1 (pl) 2012-08-31
NZ529265A (en) 2006-04-28
HK1062804A1 (zh) 2004-11-26
EA007656B1 (ru) 2006-12-29
EA200301151A1 (ru) 2004-10-28
IL158549A (en) 2009-07-20
MA26270A1 (fr) 2004-09-01
BR0209145A (pt) 2005-04-19
IL158549A0 (en) 2004-05-12
HUP0303878A2 (hu) 2004-03-01
EP1381389A4 (en) 2004-07-28
JP2005503126A (ja) 2005-02-03
CZ305819B6 (cs) 2016-03-30

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PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C12 Rejection of a patent application after its publication
RJ01 Rejection of invention patent application after publication

Open date: 20040908