CN1491687A - Medicine for treating epilepsy - Google Patents
Medicine for treating epilepsy Download PDFInfo
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- CN1491687A CN1491687A CNA031253083A CN03125308A CN1491687A CN 1491687 A CN1491687 A CN 1491687A CN A031253083 A CNA031253083 A CN A031253083A CN 03125308 A CN03125308 A CN 03125308A CN 1491687 A CN1491687 A CN 1491687A
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Abstract
The medicine for treating epilepsy is prepared with hooked uncaria, centipede, bombyx batryticatus, tabasheer, antelope horn and other nine kinds of Chinese medicinal materials and through grinding , 800-mesh sieving, and further preparation into pellet, bolus or capsule. The medicine has the functions of calming wind-syndrome, relieving muscular spasm, eliminating phlegm, tranquilizing, promoting blood circulation and dispersing blood clots, and thus high curative effect on various types of epilepsy.
Description
Technical field
The present invention relates to a kind of Chinese medicine, a kind of specifically medicine for the treatment of epileptics.
The prospect technology
Epileptics is one of world's difficult disease, clinical be divided into three types (various brain disorders occur together type, genetic type and not clear), three diseases because of the type of occurring together (send out daytime for send out at epilepsy, night to epilepsy, send out round the clock be epilepsy) patient is in the majority with children's and person between twenty and fifty.Doctor trained in Western medicine adopts phenytoin Sodium, P. R. M. Primoline, stable, antiepilepsirin, phenobarbital Drug therapy more, generally can only control or alleviate its symptom, and life-time service has a bigger infringement to people's devices such as Liver and kidney are dirty.And comparatively speaking, China's Chinese medicine is being obtained no small progress aspect the treatment study of epilepsy.As " a kind of pharmaceutical composition for the treatment of epileptics " (number of patent application 02125609, the applying date 20020724) makes by raw materials such as Carapax Eretmochelydis, Margarita, succinum, Concretio Silicea Bambusae, Arisaema Cum Bile, Scorpios, this medicine energy heat-clearing and toxic substances removing, tranquillizing the mind by relieving convulsion, suppressing the hyperactive liver to relieve the wind syndrome, the anxious chronic infantile convulsion of children's, epilepsy that treatment hyperpyrexia, scaring are caused have remarkable result.But this medicine is primarily aimed at the anxious chronic infantile convulsion of the children's who is caused by hyperpyrexia, scaring, epilepsy, does not mention the curative effect to the epileptics that causes because of other reason.
Summary of the invention
Therefore, still there is demand in people's medicine that curative effect is better treated epileptics.I on the basis of secret prescription handed down in the family from generation to generation, through research and 500 many cases clinic trial repeatedly, finished have the eliminating phlegm that dispels the wind, the medicine of the present invention of mildly regulating cold and heat, collateral dredging spasmolytic, invigorating brain and relieving mental uneasiness.
The object of the present invention is to provide a kind of medicine that can effectively treat the epileptics of three types, three diseases.
Because the epilepsy performance is very complicated, clinical minute constitutional, Secondary cases, be divided into various brain disorders occur together type, genetic type and not clear because of the type of occurring together), three diseases (send out daytime for send out at epilepsy, night to epilepsy, send out round the clock be epilepsy), its pathogenesis is many by due to expectorant, frightened, the stasis of blood etc., wherein have interconnected and be main pathology with heart spirit confused by phlegm especially, the present invention learns wildly from other's strong points on prescription basis handed down from one's ancestors, adopts the mechanism that main eliminating phlegm must relieve dizziness, high fever, infantile convulsions, epilepsy, etc. earlier.
The present invention is monarch with Ramulus Uncariae Cum Uncis, Cornu Saigae Tataricae, Concretio Silicea Bambusae, with the only expectorant that relieves dizziness, high fever, infantile convulsions, epilepsy, etc.; Select Lapis Micae Aureus, Cinnabaris etc. for use according to the state of an illness, wash drink with eliminating phlegm; Margarita powder etc. then have the relieving convulsion effect of calming the nerves; The Radix Salviae Miltiorrhizae blood circulation promoting and blood stasis dispelling; The merit that Scolopendra, Bombyx Batryticatus, Concretio silicea Bambusae seu schizostachyi all have spasmolytic, relieve dizziness, high fever, infantile convulsions, epilepsy, etc., convulsion is only taken out, the dispelling wind and heat pathogens calmness of Flos Chrysanthemi, thin He in addition, we play altogether relieve dizziness, high fever, infantile convulsions, epilepsy, etc., spasmolytic, eliminating phlegm, calm the nerves, the merit of blood circulation promoting and blood stasis dispelling.
The objective of the invention is to realize with following technical proposals: a kind of medicine for the treatment of epileptics, it is to be made by following bulk drugs: Ramulus Uncariae Cum Uncis 8-12 part, Scolopendra 8-10 part, Bombyx Batryticatus 20-30 part, Concretio Silicea Bambusae 12-20 part, Cornu Saigae Tataricae 4-6 part, Calculus Bovis 2-3 part, Cinnabaris 0.3-0.5 part, Lapis Micae Aureus 12-20 part, succinum 12-20 part, Margarita powder 1-2 part, Rhizoma Gastrodiae 20-30 part, Radix Salviae Miltiorrhizae 12-20 part, Flos Chrysanthemi 10-15 part, Herba Menthae 10-15 part.
This medicine the best is to be made by following bulk drugs: 12 parts of Ramulus Uncariae Cum Uncis, 10 parts of Scolopendras, 25 parts of Bombyx Batryticatus, 15 parts of Concretio Silicea Bambusaes, 6 parts of Cornu Saigae Tataricae, 3 parts of Calculus Boviss, 0.4 part in Cinnabaris, 15 parts of Lapis Micae Aureuss, 15 parts of succinums, 2 parts of Margarita powder, 25 parts in Rhizoma Gastrodiae, 15 parts of Radix Salviae Miltiorrhizaes, 10 parts of Flos Chrysanthemis, 10 parts of Herba Menthaes.
Above-mentioned raw materials medicated powder is broken, cross the following dusting cover of 800 orders after, water is general to be ball such as Semen phaseoli radiati size; Or refined honey ball; Or medicated powder incapsulated.
Medicine of the present invention have relieve dizziness, high fever, infantile convulsions, epilepsy, etc., spasmolytic, eliminating phlegm, calm the nerves, invigorate blood circulation, the merit of blood stasis dispelling, to three types (various brain disorders occur together type, genetic type and not clear), three diseases because of the type of occurring together (send out daytime for send out at epilepsy, night to epilepsy, send out round the clock be epilepsy) epileptics all has better therapeutic effect.
The specific embodiment
Further specify beneficial effect of the present invention with clinical observation by the following examples.
Embodiment 1: Ramulus Uncariae Cum Uncis 8g, Scolopendra 8g, Bombyx Batryticatus 20g, Concretio Silicea Bambusae 12g, Cornu Saigae Tataricae 4g, Calculus Bovis 2g, Cinnabaris 0.5g, Lapis Micae Aureus 12g, succinum 12g, Margarita powder 1g, Rhizoma Gastrodiae 20g, Radix Salviae Miltiorrhizae 12g, Flos Chrysanthemi 10g part, Herba Menthae 10g.
Above-mentioned raw materials medicated powder is broken, cross the following dusting cover of 800 orders after, water is general to be ball such as Semen phaseoli radiati size.
Embodiment 2: Ramulus Uncariae Cum Uncis 12g, Scolopendra 10g, Bombyx Batryticatus 30g, Concretio Silicea Bambusae 20g, Cornu Saigae Tataricae 6g, Calculus Bovis 3g, Cinnabaris 0.5g, Lapis Micae Aureus 20g, succinum 20g, Margarita powder 2g, Rhizoma Gastrodiae 30g, Radix Salviae Miltiorrhizae 20g, Flos Chrysanthemi 15g, Herba Menthae 15g.
Above-mentioned raw materials medicated powder is broken, the following dusting cover of mistake 800 orders, the refined honey ball.
Embodiment 3: Ramulus Uncariae Cum Uncis 12g, Scolopendra 10g, Bombyx Batryticatus 25g, Concretio Silicea Bambusae 15g, Cornu Saigae Tataricae 6g, Calculus Bovis 3g, Cinnabaris 0.4g, Lapis Micae Aureus 15g, succinum 15g, Margarita powder 2g, Rhizoma Gastrodiae 25g, Radix Salviae Miltiorrhizae 15g, Flos Chrysanthemi 15g, Herba Menthae 15g.
Above-mentioned raw materials medicated powder is broken, cross the following dusting cover of 800 orders after, with the medicated powder 0# capsule of packing into.
Experimental example: the clinical observation of the various epilepticss of Drug therapy of the present invention.
1, physical data
Accept patient's 580 examples for medical treatment, wherein man's example is women routine; Minimum 2 years old of age, maximum 48 years old; 23 years old mean age; The shortest person of medical history 2 days, elder 21 years.
2, diagnostic criteria (traditional Chinese medical science standard)
Clinical types: clinically be divided into three types, three diseases.Three types: the various brain disorders type 173 that occurs together; Gene type 143; Not clear because of the type of occurring together 264; Three diseases; Send out daytime to sending out at epilepsy 84, night to epilepsy 130, sending out round the clock and be epilepsy 366.
Clinical symptoms: the epileptics stage of attack,, its primary symptom is: patient's dizziness headache, uncomfortable in chest stretching oneself and yawn, and soon fall in a swoon and fall to the ground, obnubilation, pale complexion, gnathospasma, the eyes turning upwards, tetany, slobbering, and send the cry of similar pig sheep, even incontinence of urination and defecation; Or deflective mouth and eye, in the larynx expectorant toot, no matter occurrences in human life.Disease time several seconds, a few minutes, the longest several hours, indivedual several days.After reviving, except that fatigue and weak, the daily life diet is normal, but red tongue, white and greasy fur or greasy fur, wiry and frequent pulse or stringy and rolling pulse.
3, Therapeutic Method
Every day three times, each 3-5g, 1 month is a course of treatment, serve on 3 courses of treatment.
4, efficacy assessment standard
Recovery from illness: clinical symptoms, sign disappear, and do not have convulsive seizure more than 2 years.
Produce effects: clinical symptoms, sign disappear, and do not have convulsive seizure more than 1 year.
Take a turn for the better: clinical symptoms, sign alleviate, and the morbidity number of times reduces.
Invalid: clinical symptoms, the sign number of times that do not change, falls ill not to reduce.
5, therapeutic outcome (see Table 1, table 2 and 3)
Table 1: the relation of the course of disease and curative effect
| The course of disease | The example number | Recovery from illness | Produce effects | Take a turn for the better | Invalid |
| In 1 year | 150 | ?98 | ?45 | ?5 | ?2 |
| 1-4 | 120 | ?21 | ?30 | ?60 | ?9 |
| 5-9 | 90 | ?20 | ?22 | ?37 | ?11 |
| 10-15 | 140 | ?22 | ?21 | ?47 | ?50 |
| More than 16 years | 80 | ?3 | ?7 | ?40 | ?30 |
Annotate: the course of disease is short more, and curative effect is good more.
Table 2: constitutional 460 routine attack times and therapeutic effect relationship
| Attack times | The example number | Recovery from illness | Produce effects | Take a turn for the better | Invalid |
| 1-20 time/month | 118 | ?10 | ?20 | ?40 | ?48 |
| 2-5 time/month | 102 | ?8 | ?12 | ?50 | ?32 |
| 1-2 time/month | 154 | ?40 | ?30 | ?80 | ?4 |
| 1 time/1-12 the month | 86 | ?58 | ?21 | ?5 | ?2 |
Table 3: Secondary cases 120 routine attack times and therapeutic effect relationship
| Attack times | The example number | Recovery from illness | Produce effects | Take a turn for the better | Invalid |
| 1-20 time/month | 20 | ?0 | ?4 | ?6 | ?10 |
| 3-5 time/month | 20 | ?1 | ?3 | ?8 | ?8 |
| 1-3 time/month | 30 | ?3 | ?10 | ?6 | ?11 |
| 1 time/1-12 the month | 50 | ?10 | ?5 | ?15 | ?20 |
Annotate: the constitutional therapeutic effect is significantly better than the Secondary cases curative effect.
Claims (2)
1, a kind of medicine for the treatment of epileptics is characterized in that it is to be made by following bulk drugs: Ramulus Uncariae Cum Uncis 8-12 part, Scolopendra 8-10 part, Bombyx Batryticatus 20-30 part, Concretio Silicea Bambusae 12-20 part, Cornu Saigae Tataricae 4-6 part, Calculus Bovis 2-3 part, Cinnabaris 0.3-0.5 part, Lapis Micae Aureus 12-20 part, succinum 12-20 part, Margarita powder 1-2 part, Rhizoma Gastrodiae 20-30 part, Radix Salviae Miltiorrhizae 12-20 part, Flos Chrysanthemi 10-15 part, Herba Menthae 10-15 part.
2, a kind of medicine of treatment epileptics as claimed in claim 1 is characterized in that it is to be made by following bulk drugs: 12 parts of Ramulus Uncariae Cum Uncis, 10 parts of Scolopendras, 25 parts of Bombyx Batryticatus, 15 parts of Concretio Silicea Bambusaes, 6 parts of Cornu Saigae Tataricae, 3 parts of Calculus Boviss, 0.4 part in Cinnabaris, 15 parts of Lapis Micae Aureuss, 15 parts of succinums, 2 parts of Margarita powder, 25 parts in Rhizoma Gastrodiae, 15 parts of Radix Salviae Miltiorrhizaes, 10 parts of Flos Chrysanthemis, 10 parts of Herba Menthaes.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB031253083A CN1247245C (en) | 2003-08-22 | 2003-08-22 | Medicine for treating epilepsy |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB031253083A CN1247245C (en) | 2003-08-22 | 2003-08-22 | Medicine for treating epilepsy |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1491687A true CN1491687A (en) | 2004-04-28 |
| CN1247245C CN1247245C (en) | 2006-03-29 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB031253083A Expired - Fee Related CN1247245C (en) | 2003-08-22 | 2003-08-22 | Medicine for treating epilepsy |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1331528C (en) * | 2005-11-17 | 2007-08-15 | 西安千禾药业有限责任公司 | Medicine for treating epilepsy clonus, child convulsion, prosopospasm and its preparation method |
| CN102552713A (en) * | 2012-02-28 | 2012-07-11 | 卢卫平 | Medicine for treating epilepsy and preparation method thereof |
| CN112121064A (en) * | 2020-10-28 | 2020-12-25 | 禹州济德医院 | Chinese medicinal preparation for treating epilepsy and preparation method thereof |
-
2003
- 2003-08-22 CN CNB031253083A patent/CN1247245C/en not_active Expired - Fee Related
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1331528C (en) * | 2005-11-17 | 2007-08-15 | 西安千禾药业有限责任公司 | Medicine for treating epilepsy clonus, child convulsion, prosopospasm and its preparation method |
| CN102552713A (en) * | 2012-02-28 | 2012-07-11 | 卢卫平 | Medicine for treating epilepsy and preparation method thereof |
| CN112121064A (en) * | 2020-10-28 | 2020-12-25 | 禹州济德医院 | Chinese medicinal preparation for treating epilepsy and preparation method thereof |
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| Publication number | Publication date |
|---|---|
| CN1247245C (en) | 2006-03-29 |
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