CN1270730C - Channels sootheing and network vessel quickening pill for treating protrasion of lumbar intervertebral disci - Google Patents
Channels sootheing and network vessel quickening pill for treating protrasion of lumbar intervertebral disci Download PDFInfo
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Abstract
The present invention relates to a channel soothing and vessel dredging pill for treating the protrusion of lumbar intervertebral discs, which is characterized in that the channel soothing and vessel dredging pill for treating protrusion of lumbar intervertebral discs is prepared from 120 to 125 portions of ground beetle, 119 to 124 portions of Chinese angelica root, 90 to 95 portions of earthworm, 89 to 94 portions of hiraute shiny bugleweed herb, 90 to 95 portions of pangolin scale, 90 to 95 portions of tree peony bark, 74 to 78 portions of astragalus root, 75 to 80 portions of prepared rehmannia root, 75 to 80 portions of black-tail snake, 75 to 80 portions of pubescent angelica root, 75 to 80 portions of scorpion and 75 to 80 portions of Radix Cyathulae as raw materials according to portions by weight. According to a traditional Chinese medicine theory, through the analysis of medical theory and medical property of various medicines, the present invention is developed through long time test and clinical observation. The medicine has the functions of nourishing qi and blood and activating blood circulation to dissipate blood stasis and has good effect on treating the protrusion of intervertebral discs. The present invention has the advantages of outstanding curative effects and low expense of treatment. The present invention has another advantage of non-operative treatment. The present invention is a medicine for oral administration, and patients do not have pain in the process of treatment.
Description
Technical field
The present invention relates to Chinese medicine, particularly relate to a kind of channels sootheing and network vessel quickening pill that is used for the treatment of prolapse of lumbar intervertebral disc.
Background technology
The human spine clips intervertebral by vertebra and forms.The pressure that intervertebral disc is subjected in the time of can cushioning spinal motion, the protection spinal cord.Along with the growth at people's age, the vertebral pulp water content reduces, and fibrous elasticity on every side reduces.Long-term chronic strain or sprain suddenly can make annulus fibrosus disci intervertebralis break, and intermediary vertebral pulp is outwards mobile, even is extruded outside the fibrous ring, medically is called prolapse of lumbar intervertebral disc, and the lighter is called annuler bulge disease.
Prolapse of lumbar intervertebral disc is clinical common frdquently encountered disease, serves as main performance with lumbago and skelalgia, waist limitation of activity, sometimes with numbness, and the severe patient even the life of can not taking care of oneself.
Prolapse of lumbar intervertebral disc belongs to motherland's medical science " lumbago ", " lumbago and skelalgia " category.The traditional Chinese medical science thinks, disease in trunk, then the function of motion is not normal, and is movable unfavorable.In " element ask thorn lumbago a piece of writing ", just mention " belt vessel makes us lumbago, cannot pitching, face upward then and probably fall forward, weight lifting hinder waist ".It is impaired that its cause of disease mostly is wound, in have lose empty or be affected by the cold, damp etc., be divided into qi depression to blood stasis, wind chill blockage so distinguish its clinical disease, types such as caused by liver and kidney deficiency.
Prolapse of lumbar intervertebral disc is mainly in 30～50 person between twenty and fifty, and the old people more than 55 years old is more rare, accounts for 14.5% of primary disease sum.Prolapse of lumbar intervertebral disc, the traditional Chinese medical science is divided into Blood stasis, cold-damp disease, damp-heat syndrome, caused by liver and kidney deficiency disease etc. by disease, cause of disease difference, medication is also had any different.At present, most of medicine is to belong to comprehensive prescription, does not have according to traditional Chinese medical science disease and classifies." Taiping Royal Prescriptions. roll up 44. it is all to control waist hip pain " and say: " so husband's waist hip pain person wins by the QI and blood skin natural fibre line of meat is empty, and is subjected to air-cooled also.Kidney master waist foot, kidney master weakness, as the cold with fair wind visitor of ailment said due to cold or exposure institute between the waist hip, so make the pain ear." therefore according to the prolapse of lumbar intervertebral disc of various diseases, carry out the Therapeutic Method that different pharmaceutical stresses, can yet be regarded as and treat the good recipe of prolapse of lumbar intervertebral disc.
At present, the Therapeutic Method of clinically prolapse of lumbar intervertebral disc being carried out is varied.Doctor trained in Western medicine adopts the operative treatment primary disease, and its principle is in the outstanding intervertebral disc of excision, suitably excises downright bad ligament, part joint or the vertebral plate that thickens, to remove spinal canal stenosis or root compression.Tcm syndrome differentiation and treatment comprises oral administration and externally Chinese patent medicine, manual massage, lumbar traction etc., can play tangible blood circulation promoting and blood stasis dispelling, the anti-inflammatory analgetic effect.Modern medicine also confirms, the oral medicinal herb reaction that can reduce inflammation is shortened inflammatory phase and alleviate connective tissue forming, and promotes degenerated nerve fibers to recover, and reducing gtelatinous fibre increases, and alleviates cicatrix to the extruding of peripheral nerve tissue etc.
Summary of the invention
Purpose of the present invention just is being based on above-mentioned existing in prior technology problem, a kind of channels sootheing and network vessel quickening pill that is used for the treatment of prolapse of lumbar intervertebral disc of developing according to Traditional Chinese medical theory, but this medicine benefiting QI and nourishing blood, blood circulation promoting and blood stasis dispelling, treatment to intervertebral disc prolapse, have good effect, determined curative effect, and expense is lower.
The present invention realizes by following scheme: the channels sootheing and network vessel quickening pill that originally is used for the treatment of prolapse of lumbar intervertebral disc is to be made by following materials of weight proportions:
89～94 parts of 90～95 parts of Herba Lycopi of 119～124 parts of Pheretimas of 120～125 parts of Radix Angelicae Sinensis of Eupolyphaga Seu Steleophaga
75～80 parts of 74～78 parts of Radix Rehmanniae Preparata of 90～95 parts of Radixs Astragali of 90～95 parts of Cortex Moutans of Squama Manis
75～80 parts of 75～80 parts of Radix Achyranthis Bidentataes of 75～80 portions of Scorpios of 75～80 parts of Radix Angelicae Pubescentiss of Zaocys
The compound method and the technological process of this medicine are as follows:
Join part at first by weight than taking by weighing above-mentioned 12 flavor medicines, divide two groups of processing levigations:
First group: Radix Angelicae Sinensis, pulverize with Universalpulverizer earlier, sieve, flour extraction is 96～98%.The gained fine powder, the processing sterilization.This medicine contains volatile component, and it is long to be difficult for heat time heating time, sterilize up to standard after, sealed storage, with anti-pollution, stand-by.
Second group: Eupolyphaga Seu Steleophaga, Pheretima, Herba Lycopi, Squama Manis, Cortex Moutan, the Radix Astragali, Radix Rehmanniae Preparata, Zaocys, Radix Angelicae Pubescentis, Scorpio, Radix Achyranthis Bidentatae, mix homogeneously drops into Universalpulverizer and pulverizes, and sieves, and flour extraction is 96～98%.The gained fine powder, heat sterilization.Heating-up temperature is 100 degree, according in batches what, sterilize 25～40 minutes, total number of bacteria by 10000-100000/g reduce to 500/below the g, mycete by 1000-1500 individual/g is reduced to 100/g, airtight preservation.
With above two groups of fine powder mix homogeneously, add pure water, drop into pill in the pellet processing machine.Wet ball is after the following drying of 60～90 degree, and irregular parts such as the dispersion in the rejecting pill, distortion are upward spared Pulvis Talci, and with the above active carbon coating of 120 orders, consumption is about 0.3%, after the polishing.
The pharmacological property of medicine of the present invention is analyzed as follows:
Eupolyphaga Seu Steleophaga, salty, cold, go into Liver Channel, removing blood stasis is treated folding and is hindered.Amplification on Canon of Materia Medica is said: Eupolyphaga Seu Steleophaga has treats the effect that folding is hindered dissipating blood stasis blood.Radix Angelicae Sinensis, sweet, suffering, hardship, temperature is gone into liver, the heart, spleen channel." book on Chinese herbal medicine through hundred kinds of records " said: " when being classified as the medicine that blood man must use ... allly close, pleasant and cloudy, relieve inflammation or internal heat, sending down the abnormal ascending QI, promote the production of body fluid, dispel the wind, sharp key, all lead to the product of systems ", invigorate blood circulation for enriching blood, the product of menstruction regulating and pain relieving, two medicines one are controlled a benefit, are monarch drug altogether.Pheretima goes into liver, spleen, lung meridian, has dredge the meridian passage, and is good to pyretic arthralgia redness and swelling of joints burning pain, joint stuffiness curative effect.Squama Manis is gone into liver stomach warp, can the meridian dredging, control insensitive impediment.The Herba Lycopi, bitter in the mouth, suffering, little wet, go into spleen, Liver Channel, the merit of promoting blood circulation to restore menstrual flow is arranged.Cortex Moutan is gone into the heart, liver, kidney channel, and the merit of clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling is arranged.Four medicines are ministerial drug altogether.The Radix Astragali, sweet in the mouth, tepor is gone into spleen, lung meridian, is the QI invigorating key medicine.Radix Rehmanniae Preparata, " pearl sac " said: " benefit increases the moon for main filling blood, kidney nourishing water ", the YIN nourishing of enriching blood.Zaocys, sweet, flat, go into Liver Channel, have dispel the wind, the effect of dehumidifying, collateral dredging.Scorpio, Liver Channel is put down, gone into to acrid in the mouth, cures mainly the extremities joint joint stuffiness, hemiplegia.Radix Angelicae Pubescentis is gone into kidney channel, has the effect of leading diffusing, sensible whole body, treatment of arthritis and promoting collateral and channels." not Lu " be said: " treat all harmful wind, hundred arthralgia wind, do not have ask new, " above five kinds of Chinese medicine, help the monarch and his subjects, reach disease institute, be adjuvant drug altogether, Radix Achyranthis Bidentatae can draw behavior messenger drug under all medicines.
Taking a broad view of full side, is the rule of treatment with blood circulation promoting and blood stasis dispelling, promoting the flow of QI in the collateral by warming the meridian, focuses on and improves stagnation of blood stasis, can compensate qi and blood consolidating, reinforcement and elimination in combination, treating both the principal and the secondary aspects of a disease at the same time, pathogenesis hits.This medicine is the slow product of gentle property, and no Da Xin, big heat, high strong agent in Great Cold are beneficial to patient and take for a long time.
Clinical observation and test data
(1) clinical observation: from the court's outpatient service, inpatient, select 100 routine model cases, the men and women half and half, and age bracket is respectively 18～30 years old 20 example, 30～40 years old 30 example, 40～50 years old 40 example, 10 examples more than 50 years old.
The bone healthy pill that separate case is declared patent, the course of treatment and curative effect are taken in the present invention's cooperation: one month is a course of treatment, takes three courses of treatment continuously, takes medicine every day 3 times, and each 6 grams simultaneously, are aided with maneuver massage, traction and plaster outer plaster, hardboard bed rest for sleeping in etc.Course of disease 1-3 person effective percentage is 96%, and 3-5 person's effective percentage is 89%, and 5-7 person's effective percentage is 75%.This shows, be the rule of treatment with blood circulation promoting and blood stasis dispelling, promoting the flow of QI in the collateral by warming the meridian, and it is evident in efficacy to take dredge the meridian passage pill for curing prolapse of lumbar intervertebral disc of the present invention; The 2nd, the course of disease time, short more curative effect was remarkable more, early to find that early treatment is for well.
(2) drug effect, toxicological test:
Great new medicine science and technology institute result of the test is as follows through Henan:
Acute toxicity test: with this medicine be equivalent to clinical application 120 extraordinarily pure water be mixed with suspension, give mouse stomach, a continuous week is seen and looks into, outward appearance, action activity, the mental status, diet, drinking-water, feces, fur, the colour of skin, breathing are all normal, the no abnormal secretions in nose, eye and oral cavity, acute toxic reaction and death do not appear, healthy survival, weight increase.
Long term toxicity test: the 30-50 that this medicine is equivalent to clinical application doubly is mixed with suspension, gives rat oral gavage, and successive administration was seen and looked in 3 months, and the figure does not have pathology and changes, and slowness do not occur and changes.
The test of pesticide effectiveness: be mice, rat paw, ears, blood capillary, the administration respectively of two axil otch, cause inflammation, pain and swelling etc., the 10-20 of this medicine clinical application doubly is mixed with suspension with pure water is rat oral gavage, be mouse stomach with being equivalent to 12.5-25 times of suspension, sight in continuous 7 days is looked into, and medicine of the present invention has tangible detumescence, antiinflammatory, analgesic activity.
The present invention has following advantage compared to existing technology: non-operative treatment, and medication for oral administration, expense is low, and the patient is no pain in therapeutic process, and this prescription lays particular emphasis on deficient qi and blood, flesh natural fibre line of meat inanition, but treating both the principal and secondary aspects of a disease, Special medicine for special disease, therapeutic effect is good, is applicable to all kinds of crowds.
The specific embodiment
The present invention is described further below in conjunction with embodiment, but does not limit the present invention:
Embodiment 1
(1) join part by weight and state 12 herbal medicines than taking off:
Eupolyphaga Seu Steleophaga 120g, Radix Angelicae Sinensis 122g, Pheretima 90g, Herba Lycopi 89～94g, Squama Manis 95g, Cortex Moutan 95g, Radix Astragali 75g, Radix Rehmanniae Preparata 80g, Zaocys 7g, Radix Angelicae Pubescentis 80g, Scorpio 78g, Radix Achyranthis Bidentatae 80g are standby.
(2) Radix Angelicae Sinensis is pulverized with Universalpulverizer earlier, sieves, and flour extraction is 96～98%.The gained fine powder, the processing sterilization.This medicine contains volatile component, and it is long to be difficult for heat time heating time, sterilize up to standard after, sealed storage, with anti-pollution, stand-by.
(3) Eupolyphaga Seu Steleophaga, Pheretima, Herba Lycopi, Squama Manis, Cortex Moutan, the Radix Astragali, Radix Rehmanniae Preparata, Zaocys, Radix Angelicae Pubescentis, Scorpio, Radix Achyranthis Bidentatae, mix homogeneously drops into Universalpulverizer and pulverizes, and sieves, and flour extraction is 96～98%.The gained fine powder, the processing sterilization.Heating-up temperature is 100 degree, according in batches what, sterilize 25～40 minutes, total number of bacteria by 10000-100000/g reduce to 500/below the g, mycete by 1000-1500 individual/g is reduced to 100/g, airtight preservation.
(4) with above two groups of fine powder mix homogeneously, add pure water, drop into pill in the pellet processing machine.Wet ball is after the following drying of 60～90 degree, and irregular parts such as the dispersion in the rejecting pill, distortion are upward spared Pulvis Talci, and with the above active carbon coating of 120 orders, consumption is about 0.3%, is medicine of the present invention after the polishing.
Embodiment 2
Join part by weight and state 12 herbal medicines than taking off:
Eupolyphaga Seu Steleophaga 125g, Radix Angelicae Sinensis 124g, Pheretima 92g, Herba Lycopi 94g, Squama Manis 95g, Cortex Moutan 91g, Radix Astragali 78g, Radix Rehmanniae Preparata 76g, Zaocys 78g,, Radix Angelicae Pubescentis 76g, Scorpio 76g, Radix Achyranthis Bidentatae 75g be standby.
The preparation method of present embodiment and embodiment 1 are identical.
Claims (1)
1, a kind of channels sootheing and network vessel quickening pill that is used for the treatment of prolapse of lumbar intervertebral disc is characterized in that: it is to be made by following materials of weight proportions:
89～94 parts of 90～95 parts of Herba Lycopi of 119～124 parts of Pheretimas of 120～125 parts of Radix Angelicae Sinensis of Eupolyphaga Seu Steleophaga
75～80 parts of 74～78 parts of Radix Rehmanniae Preparata of 90～95 parts of Radixs Astragali of 90～95 parts of Cortex Moutans of Squama Manis
75～80 parts of 75～80 parts of Radix Achyranthis Bidentataes of 75～80 portions of Scorpios of 75～80 parts of Radix Angelicae Pubescentiss of Zaocys.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2005100174790A CN1270730C (en) | 2005-04-01 | 2005-04-01 | Channels sootheing and network vessel quickening pill for treating protrasion of lumbar intervertebral disci |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2005100174790A CN1270730C (en) | 2005-04-01 | 2005-04-01 | Channels sootheing and network vessel quickening pill for treating protrasion of lumbar intervertebral disci |
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| Publication Number | Publication Date |
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| CN1686214A CN1686214A (en) | 2005-10-26 |
| CN1270730C true CN1270730C (en) | 2006-08-23 |
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| CNB2005100174790A Expired - Fee Related CN1270730C (en) | 2005-04-01 | 2005-04-01 | Channels sootheing and network vessel quickening pill for treating protrasion of lumbar intervertebral disci |
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Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102028810B (en) * | 2010-11-19 | 2012-01-25 | 张民 | Traditional Chinese medicine for treating lumbar intervertebral disc protrusion |
| CN105919964A (en) * | 2016-05-31 | 2016-09-07 | 成都长青制药有限公司 | Coating method of black coating solid preparation |
| CN106109691A (en) * | 2016-08-24 | 2016-11-16 | 沈友良 | A kind of pharmaceutical composition treating prolapse of lumbar intervertebral disc |
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