CN1471587A - 肺癌的基因标记 - Google Patents

肺癌的基因标记 Download PDF

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Publication number
CN1471587A
CN1471587A CNA018115438A CN01811543A CN1471587A CN 1471587 A CN1471587 A CN 1471587A CN A018115438 A CNA018115438 A CN A018115438A CN 01811543 A CN01811543 A CN 01811543A CN 1471587 A CN1471587 A CN 1471587A
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CN
China
Prior art keywords
lung cancer
blood
markers
pcr
cells
Prior art date
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Pending
Application number
CNA018115438A
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English (en)
Chinese (zh)
Inventor
M・米特苏哈施
M·米特苏哈施
钒屠
H·卡姆巴拉
厮漳杉
H·马特苏纳加
吣吕
M·卡瓦穆拉
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hitachi Ltd
Resonac Corp
Original Assignee
Hitachi Chemical Co Ltd
Hitachi Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hitachi Chemical Co Ltd, Hitachi Ltd filed Critical Hitachi Chemical Co Ltd
Publication of CN1471587A publication Critical patent/CN1471587A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57423—Specifically defined cancers of lung
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/686—Polymerase chain reaction [PCR]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Wood Science & Technology (AREA)
  • Pathology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CNA018115438A 2000-06-21 2001-06-21 肺癌的基因标记 Pending CN1471587A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US21572700P 2000-06-21 2000-06-21
US60/215,727 2000-06-21
US24397600P 2000-10-27 2000-10-27
US60/243,976 2000-10-27

Publications (1)

Publication Number Publication Date
CN1471587A true CN1471587A (zh) 2004-01-28

Family

ID=26910326

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA018115438A Pending CN1471587A (zh) 2000-06-21 2001-06-21 肺癌的基因标记

Country Status (6)

Country Link
US (2) US7214781B2 (enExample)
EP (1) EP1356093A2 (enExample)
JP (1) JP4392163B2 (enExample)
CN (1) CN1471587A (enExample)
AU (1) AU2001270082A1 (enExample)
WO (1) WO2001098539A2 (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100343280C (zh) * 2004-02-04 2007-10-17 香港中文大学 癌症病程及治疗反应的标志物cudr
WO2012031374A1 (zh) * 2010-09-09 2012-03-15 北京同为时代生物技术有限公司 用于诊断上皮源性癌症的血液标志物及其单克隆抗体
CN104603288A (zh) * 2012-06-06 2015-05-06 生物医学研究机构基金会 用于肺癌转移的诊断、预后和治疗的方法

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL158293A0 (en) 2001-04-10 2004-05-12 Agensys Inc Nucleic acid and corresponding protein entitled 158p3d2 and pharmaceutical compositions containing the same
EP1510587B1 (en) * 2002-05-21 2011-07-13 Sysmex Corporation Nucleic acid amplification primers for detecting cytokeratins and examination method with the use of the primers
GB0215509D0 (en) * 2002-07-04 2002-08-14 Novartis Ag Marker genes
JP2009504168A (ja) 2005-08-17 2009-02-05 メディクシス エス．エー． Ｃｋ１９発現を確認する組成物及び方法
WO2007092105A1 (en) * 2006-02-03 2007-08-16 Hill's Pet Nutrition, Inc. Method for evaluating kidney function in a feline by measuring ghrelin hormone levels
WO2007130967A2 (en) * 2006-05-01 2007-11-15 Siemens Healthcare Diagnostics Inc. Novel oligonucleotide primers and methods for dna replication
KR101443214B1 (ko) 2007-01-09 2014-09-24 삼성전자주식회사 폐암 환자 또는 폐암 치료를 받은 폐암 환자의 폐암 재발 위험을 진단하기 위한 조성물, 키트 및 마이크로어레이
WO2009043115A1 (en) * 2007-10-04 2009-04-09 Fermiscan Australia Pty Limited Method for identifying biomarkers which are diagnostic for a pathological condition
JP2013099253A (ja) * 2010-03-11 2013-05-23 Intec Systems Institute Inc 肺癌または子宮頸癌の診断マーカー
MY205689A (en) 2017-10-02 2024-11-06 Visterra Inc Antibody molecules to cd138 and uses thereof
WO2020007898A1 (en) * 2018-07-04 2020-01-09 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and compositions for treating brain injury or neurodegenerative disease
US12338291B2 (en) * 2019-06-17 2025-06-24 Visterra, Inc. Humanized antibody molecules to CD138 and uses thereof
KR20210020417A (ko) * 2019-08-14 2021-02-24 연세대학교 산학협력단 메티오닐-티알엔에이 합성효소 및 판사이토케라틴을 이용한 폐암 진단 방법

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5272057A (en) * 1988-10-14 1993-12-21 Georgetown University Method of detecting a predisposition to cancer by the use of restriction fragment length polymorphism of the gene for human poly (ADP-ribose) polymerase
ATE345387T1 (de) 1998-03-18 2006-12-15 Corixa Corp Verbindungen und verfahren für therapie und diagnose von lungenkrebs

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100343280C (zh) * 2004-02-04 2007-10-17 香港中文大学 癌症病程及治疗反应的标志物cudr
WO2012031374A1 (zh) * 2010-09-09 2012-03-15 北京同为时代生物技术有限公司 用于诊断上皮源性癌症的血液标志物及其单克隆抗体
US9255142B2 (en) 2010-09-09 2016-02-09 Beijing Cotimes Biotech Co., Ltd. Blood markers for diagnosing epithelium derived cancers and monoclonal antibodies thereof
CN106706914A (zh) * 2010-09-09 2017-05-24 北京同为时代生物技术有限公司 用于诊断上皮源性癌症的血液标志物及单克隆抗体
US9840551B2 (en) 2010-09-09 2017-12-12 Beijing Cotimes Biotech Co. Ltd. Blood markers for diagnosing epithelium derived cancers and monoclonal antibodies thereof
CN106706914B (zh) * 2010-09-09 2018-10-19 北京同为时代生物技术有限公司 用于诊断上皮源性癌症的血液标志物及单克隆抗体
CN104603288A (zh) * 2012-06-06 2015-05-06 生物医学研究机构基金会 用于肺癌转移的诊断、预后和治疗的方法
US10006091B2 (en) 2012-06-06 2018-06-26 Fundació Institut De Recerca Biomèdica (Irb Barcelona) Method for the diagnosis, prognosis and treatment of lung cancer metastasis
CN104603288B (zh) * 2012-06-06 2018-12-14 生物医学研究机构基金会 用于肺癌转移的诊断、预后和治疗的方法
US11352673B2 (en) 2012-06-06 2022-06-07 Fundacio Institut De Recerca Biomedica (Irb Barcelona) Method for the diagnosis, prognosis and treatment of lung cancer metastasis

Also Published As

Publication number Publication date
WO2001098539A2 (en) 2001-12-27
US7214781B2 (en) 2007-05-08
WO2001098539A3 (en) 2003-08-14
EP1356093A2 (en) 2003-10-29
JP4392163B2 (ja) 2009-12-24
US20060275783A1 (en) 2006-12-07
US20030215828A1 (en) 2003-11-20
JP2004500895A (ja) 2004-01-15
AU2001270082A1 (en) 2002-01-02

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