CN1449797A - Compound chenxiang gastric tablet and preparation process thereof - Google Patents

Compound chenxiang gastric tablet and preparation process thereof Download PDF

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Publication number
CN1449797A
CN1449797A CN 03116870 CN03116870A CN1449797A CN 1449797 A CN1449797 A CN 1449797A CN 03116870 CN03116870 CN 03116870 CN 03116870 A CN03116870 A CN 03116870A CN 1449797 A CN1449797 A CN 1449797A
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China
Prior art keywords
fine powder
powder
radix
magnesium carbonate
sodium bicarbonate
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CN 03116870
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Chinese (zh)
Inventor
杨泽基
鞠重华
俞振铃
邹隆信
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CHENGZHI XINFENG PHARMACEUTICAL JIANG XI LLC
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CHENGZHI XINFENG PHARMACEUTICAL JIANG XI LLC
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Priority to CN 03116870 priority Critical patent/CN1449797A/en
Publication of CN1449797A publication Critical patent/CN1449797A/en
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Abstract

The present invention discloses a Chinese patent medicine compound chenxiangwei tablet and its preparation method. It is smade from rhubarb, tangerine peel, saussurea root, acorus root, sodium hydrogen carbonate, heavy magnesium carbonate and aluminium hydroxide as main raw material, adding starch and starch slurry as auxiliary material through a certain preparation process. Said invented tablet preparation has the functions of promoting circulation of qi, regulating the stomach, relieving gastric hyperacidity to alleviate stomachache and can be used for curing diseases of gastoduodenal ulcer, chronic gastritis and epigastralgia due to stagnation of qi, abdominal distention and eructation and acid regurgitation, etc.

Description

Compound sheet and preparation method thereof
Technical field
What the present invention relates to is Chinese patent medicine in the field of medicaments, especially relates to a kind of compound sheet with relieving QI stagnancy in the stomach, relieving gastric hyperacidity to alleviate stomachache effect and preparation method thereof.
Background technology
The compound sheet is the Chinese medicine and western medicine compound preparation, because the production technology difference of the together general Chinese patent medicine tablet of this process characteristic, the composition that traditional handicraft is extracted is few, and the diameter of fine powder is excessive, and active ingredient is difficult for being absorbed, and therapeutic effect is relatively poor.
Summary of the invention
The object of the present invention is to provide a kind of compound sheet that composition diameters many, fine powder are little, active ingredient easily is absorbed, therapeutic effect is good and preparation method thereof with relieving QI stagnancy in the stomach, relieving gastric hyperacidity to alleviate stomachache effect, extraction.
The objective of the invention is such realization: the present invention is made up of following raw material by weight:
Pericarpium Citri Reticulatae 70-98 gram Radix Aucklandiae 10-30 gram
Rhizoma Acori Graminei 8-14 gram Radix Et Rhizoma Rhei 10-30 gram
Sodium bicarbonate 1-24 gram aluminium hydroxide 70-98 gram
Heavy Magnesium Carbonate 10-24 gram
Its best proportioning is:
The Pericarpium Citri Reticulatae 84 gram Radix Aucklandiae 20 grams
Rhizoma Acori Graminei 11 gram Radix Et Rhizoma Rhei 20 grams
Sodium bicarbonate 17 gram aluminium hydroxide 84 grams
Heavy Magnesium Carbonate 17 grams
Preparation method of the present invention is:
First kind of preparation method:
(1), Pericarpium Citri Reticulatae, the Radix Aucklandiae, Rhizoma Acori Graminei, four kinds of medical materials of Radix Et Rhizoma Rhei are cleaned respectively, remove impurity, the pulverize separately powdered obtains Dried Tangerine Peel, Common Aucklandia Root, Grassleaf Sweetflag Rhizome, Rhubarb then;
(2), with sodium bicarbonate, Heavy Magnesium Carbonate, aluminium hydroxide pulverize separately powdered, obtain sodium bicarbonate powder, Heavy Magnesium Carbonate powder, aluminium-hydroxide powder;
(3), Dried Tangerine Peel, Common Aucklandia Root, Grassleaf Sweetflag Rhizome, Rhubarb, sodium bicarbonate powder, Heavy Magnesium Carbonate powder, aluminium-hydroxide powder are mixed, add starch again and mix, stir, obtain mixture by the equivalent incremental method;
(4), in mixture, add starch slurry, the system soft material is granulated, drying, tabletting gets product after the packing.
Described Dried Tangerine Peel, Common Aucklandia Root, Grassleaf Sweetflag Rhizome, Rhubarb, sodium bicarbonate powder, Heavy Magnesium Carbonate powder, aluminium-hydroxide powder are 40-100 order fine powder, superfine powder or nano powder.
Second kind of preparation method:
(1), Pericarpium Citri Reticulatae, the Radix Aucklandiae, Rhizoma Acori Graminei, four kinds of medical materials of Radix Et Rhizoma Rhei are cleaned respectively, remove impurity, be up to the standards;
(2), Radix Et Rhizoma Rhei powder is broken into fine powder, obtain the Radix Et Rhizoma Rhei fine powder;
(3), be ground into coarse powder after three kinds of medical materials of Pericarpium Citri Reticulatae, the Radix Aucklandiae, Rhizoma Acori Graminei are mixed, from coarse powder, extract volatile oil more according to a conventional method, and ground-slag is broken into fine powder, obtain Pericarpium Citri Reticulatae, the Radix Aucklandiae, Rhizoma Acori Graminei fine powder;
(4), sodium bicarbonate, Heavy Magnesium Carbonate, aluminium hydroxide pulverize separately are become fine powder, obtain sodium bicarbonate fine powder, Heavy Magnesium Carbonate fine powder, aluminium hydroxide fine powder;
(5), Pericarpium Citri Reticulatae, the Radix Aucklandiae, Rhizoma Acori Graminei fine powder, sodium bicarbonate fine powder, Heavy Magnesium Carbonate fine powder, aluminium hydroxide fine powder are carried out mix homogeneously by the equivalent incremental method;
(6), again add starch slurry, the system soft material is granulated, and drying adds volatile oil, mixing, and tabletting gets product after the packing.
The third preparation method:
(1), with the washing respectively of four kinds of medical materials of Pericarpium Citri Reticulatae, the Radix Aucklandiae, Rhizoma Acori Graminei, Radix Et Rhizoma Rhei, remove impurity, be up to the standards;
(2), Radix Et Rhizoma Rhei, Pericarpium Citri Reticulatae, the Radix Aucklandiae, four kinds of medical material pulverize separately of Rhizoma Acori Graminei are become 60-100 purpose fine powder, obtain Radix Et Rhizoma Rhei fine powder, Pericarpium Citri Reticulatae fine powder, Radix Aucklandiae fine powder, Rhizoma Acori Graminei fine powder;
(3), sodium bicarbonate, Heavy Magnesium Carbonate, aluminium hydroxide pulverize separately are become fine powder, obtain sodium bicarbonate fine powder, Heavy Magnesium Carbonate fine powder, aluminium hydroxide fine powder;
(4), with Radix Et Rhizoma Rhei fine powder, Pericarpium Citri Reticulatae fine powder, Radix Aucklandiae fine powder, Rhizoma Acori Graminei fine powder, sodium bicarbonate fine powder, Heavy Magnesium Carbonate fine powder, aluminium hydroxide fine powder mix homogeneously, obtain Chinese and Western medicated powder;
(5), above-mentioned mixed uniform Chinese and Western medicated powder is ground into superfine powder or nano powder by pulverizer, add starch slurry then, get product after granulation, drying, tabletting, the packing.
The present invention is to be primary raw material with Radix Et Rhizoma Rhei, Pericarpium Citri Reticulatae, the Radix Aucklandiae, Rhizoma Acori Graminei, sodium bicarbonate, Heavy Magnesium Carbonate, aluminium hydroxide, is aided with adjuvants such as starch, starch slurry again, forms by certain prepared.Chinese herb rhubarb purges heat unobstructed, removing pathogenic heat from blood and toxic substance from the body, the Pericarpium Citri Reticulatae regulating qi-flowing for strengthening spleen, but Radix Aucklandiae promoting the circulation of QI to relieve pain, strengthening the spleen to promote digestion, Rhizoma Acori Graminei can whet the appetite in removing dampness, sodium bicarbonate can neutralize rapidly or cushion gastric acid, therefore compound sheet of the present invention has relieving QI stagnancy in the stomach, the effect of relieving gastric hyperacidity to alleviate stomachache, be used for gastric and duodenal ulcers, qi stagnation type pain of gastral cavity such as chronic gastritis, gastral cavity abdomen feeling of fullness, symptoms such as dim gas acid regurgitation, the present invention has compared with prior art: production technology more becomes to improving rationally, quality standard and product stability improve greatly, the effect duration of medicine reached more than 3 years, and it is many to have a composition of extraction, the diameter of fine powder is little, active ingredient easily is absorbed, the advantage that therapeutic effect is good.
The specific embodiment
Below in conjunction with embodiment the present invention is described in further detail, but should understands the non-scope that only limits to these embodiment of scope of the present invention.
Embodiment 1:
(1), Pericarpium Citri Reticulatae, the Radix Aucklandiae, Rhizoma Acori Graminei, four kinds of medical materials of Radix Et Rhizoma Rhei are cleaned respectively, remove impurity, pulverize separately becomes 40 order fine powders then, obtains Pericarpium Citri Reticulatae fine powder, Radix Aucklandiae fine powder, Rhizoma Acori Graminei fine powder, Radix Et Rhizoma Rhei fine powder;
(2), sodium bicarbonate, Heavy Magnesium Carbonate, aluminium hydroxide pulverize separately are become 40 order fine powders, obtain sodium bicarbonate fine powder, Heavy Magnesium Carbonate fine powder, aluminium hydroxide fine powder;
(3), take by weighing Pericarpium Citri Reticulatae fine powder 70 grams, Radix Aucklandiae fine powder 10 grams, Rhizoma Acori Graminei fine powder 8 grams, Radix Et Rhizoma Rhei fine powder 10 grams, sodium bicarbonate fine powder 10 grams, Heavy Magnesium Carbonate fine powder 10 grams, aluminium hydroxide fine powder 70 grams respectively, then they are mixed, adding starch again mixes by the equivalent incremental method, stir, obtain mixture;
(4), in mixture, add starch slurry, the system soft material is granulated, drying, compacting gets product after the packing in flakes.
Embodiment 2:
(1), Pericarpium Citri Reticulatae, the Radix Aucklandiae, Rhizoma Acori Graminei, four kinds of medical materials of Radix Et Rhizoma Rhei are cleaned respectively, remove impurity, pulverize separately becomes nano powder then, obtains Pericarpium Citri Reticulatae nano powder, Radix Aucklandiae nano powder, Rhizoma Acori Graminei nano powder, Radix Et Rhizoma Rhei nano powder;
(2), with sodium bicarbonate, Heavy Magnesium Carbonate, aluminium hydroxide pulverize separately powdered, obtain sodium bicarbonate nano powder, Heavy Magnesium Carbonate nano powder, aluminium hydrate nano powder;
(3), take by weighing Pericarpium Citri Reticulatae nano powder 98 grams, Radix Aucklandiae nano powder 30 grams, Rhizoma Acori Graminei nano powder 14 grams, Radix Et Rhizoma Rhei nano powder 30 grams, sodium bicarbonate nano powder 24 grams, Heavy Magnesium Carbonate nano powder 24 grams, aluminium hydrate nano powder 98 grams respectively, then they are mixed, adding starch again mixes by the equivalent incremental method, stir, obtain mixture;
(4), in mixture, add starch slurry, the system soft material is granulated, drying, compacting gets product after the packing in flakes.
Embodiment 3:
(1), Pericarpium Citri Reticulatae, the Radix Aucklandiae, Rhizoma Acori Graminei, four kinds of medical materials of Radix Et Rhizoma Rhei are cleaned respectively, remove impurity, be up to the standards;
(2), take by weighing 20 the gram Radix Et Rhizoma Rhei, Radix Et Rhizoma Rhei powder is broken into superfine powder, obtain the Radix Et Rhizoma Rhei superfine powder;
Take by weighing Pericarpium Citri Reticulatae 84 grams, the Radix Aucklandiae 20 grams, Rhizoma Acori Graminei 11 grams, then these three kinds of medical materials are mixed, be ground into coarse powder, from coarse powder, extract volatile oil more according to a conventional method, and ground-slag is broken into superfine powder, obtain Pericarpium Citri Reticulatae, the Radix Aucklandiae, Rhizoma Acori Graminei superfine powder (3), respectively;
Take by weighing sodium bicarbonate 17 grams, Heavy Magnesium Carbonate 17 grams, aluminium hydroxide 84 grams, then their pulverize separately are become superfine powder, obtain sodium bicarbonate superfine powder, Heavy Magnesium Carbonate superfine powder, aluminium hydroxide superfine powder (4), respectively;
(5), Pericarpium Citri Reticulatae, the Radix Aucklandiae, Rhizoma Acori Graminei superfine powder, sodium bicarbonate superfine powder, Heavy Magnesium Carbonate superfine powder, aluminium hydroxide superfine powder are carried out mix homogeneously by the equivalent incremental method;
(6), again add starch slurry, the system soft material is granulated, and drying adds volatile oil, mixing, and compacting gets product after the packing in flakes.
Embodiment 4:
(1), with the washing respectively of four kinds of medical materials of Pericarpium Citri Reticulatae, the Radix Aucklandiae, Rhizoma Acori Graminei, Radix Et Rhizoma Rhei, remove impurity, be up to the standards;
(2), respectively take by weighing Pericarpium Citri Reticulatae 80 grams, the Radix Aucklandiae 25 grams, Rhizoma Acori Graminei 12 grams, Radix Et Rhizoma Rhei 15 grams, these four kinds of medical material pulverize separately become 100 order fine powders then, obtain Radix Et Rhizoma Rhei fine powder, Pericarpium Citri Reticulatae fine powder, Radix Aucklandiae fine powder, Rhizoma Acori Graminei fine powder;
(3), take by weighing sodium bicarbonate 75 grams, Heavy Magnesium Carbonate 20 grams, aluminium hydroxide 75 grams respectively, then sodium bicarbonate, Heavy Magnesium Carbonate, aluminium hydroxide pulverize separately are become 100 order fine powders, obtain sodium bicarbonate fine powder, Heavy Magnesium Carbonate fine powder, aluminium hydroxide fine powder;
(4), with Radix Et Rhizoma Rhei fine powder, Pericarpium Citri Reticulatae fine powder, Radix Aucklandiae fine powder, Rhizoma Acori Graminei fine powder, sodium bicarbonate fine powder, Heavy Magnesium Carbonate fine powder, aluminium hydroxide fine powder mix homogeneously, obtain Chinese and Western medicated powder;
(5), above-mentioned mixed uniform Chinese and Western medicated powder is ground into superfine powder or nano powder by pulverizer, add starch slurry then, granulate, dry, compacting in flakes, get product after the packing.

Claims (6)

1, a kind of compound sheet is characterized in that: be made up of following raw material by weight:
Pericarpium Citri Reticulatae 70-98 gram Radix Aucklandiae 10-30 gram
Rhizoma Acori Graminei 8-14 gram Radix Et Rhizoma Rhei 10-30 gram
Sodium bicarbonate 1-24 gram aluminium hydroxide 70-98 gram
Heavy Magnesium Carbonate 10-24 gram.
2, compound sheet as claimed in claim 1 is characterized in that: its best proportioning is:
The Pericarpium Citri Reticulatae 84 gram Radix Aucklandiae 20 grams
Rhizoma Acori Graminei 11 gram Radix Et Rhizoma Rhei 20 grams
Sodium bicarbonate 17 gram aluminium hydroxide 84 grams
Heavy Magnesium Carbonate 17 grams.
3, the method for preparation compound sheet as claimed in claim 1 or 2 is characterized in that:
(1), Pericarpium Citri Reticulatae, the Radix Aucklandiae, Rhizoma Acori Graminei, four kinds of medical materials of Radix Et Rhizoma Rhei are cleaned respectively, remove impurity, the pulverize separately powdered obtains Dried Tangerine Peel, Common Aucklandia Root, Grassleaf Sweetflag Rhizome, Rhubarb then;
(2), with sodium bicarbonate, Heavy Magnesium Carbonate, aluminium hydroxide pulverize separately powdered, obtain sodium bicarbonate powder, Heavy Magnesium Carbonate powder, aluminium-hydroxide powder;
(3), Dried Tangerine Peel, Common Aucklandia Root, Grassleaf Sweetflag Rhizome, Rhubarb, sodium bicarbonate powder, Heavy Magnesium Carbonate powder, aluminium-hydroxide powder are mixed, add starch again and mix, stir, obtain mixture by the equivalent incremental method;
(4), in mixture, add starch slurry, the system soft material is granulated, drying, tabletting gets product after the packing.
4, preparation method as claimed in claim 3 is characterized in that: described Dried Tangerine Peel, Common Aucklandia Root, Grassleaf Sweetflag Rhizome, Rhubarb, sodium bicarbonate powder, Heavy Magnesium Carbonate powder, aluminium-hydroxide powder are 40-100 order fine powder, superfine powder or nano powder.
5, the method for preparation compound sheet as claimed in claim 1 or 2 is characterized in that:
(1), Pericarpium Citri Reticulatae, the Radix Aucklandiae, Rhizoma Acori Graminei, four kinds of medical materials of Radix Et Rhizoma Rhei are cleaned respectively, remove impurity, be up to the standards;
(2), Radix Et Rhizoma Rhei powder is broken into fine powder, obtain the Radix Et Rhizoma Rhei fine powder;
(3), be ground into coarse powder after three kinds of medical materials of Pericarpium Citri Reticulatae, the Radix Aucklandiae, Rhizoma Acori Graminei are mixed, from coarse powder, extract volatile oil more according to a conventional method, and ground-slag is broken into fine powder, obtain Pericarpium Citri Reticulatae, the Radix Aucklandiae, Rhizoma Acori Graminei fine powder;
(4), sodium bicarbonate, Heavy Magnesium Carbonate, aluminium hydroxide pulverize separately are become fine powder, obtain sodium bicarbonate fine powder, Heavy Magnesium Carbonate fine powder, aluminium hydroxide fine powder;
(5), Radix Et Rhizoma Rhei grease, Pericarpium Citri Reticulatae, the Radix Aucklandiae, Rhizoma Acori Graminei fine powder, sodium bicarbonate fine powder, Heavy Magnesium Carbonate fine powder, aluminium hydroxide fine powder are carried out mix homogeneously by the equivalent incremental method;
(6), again add starch slurry, the system soft material is granulated, and drying adds volatile oil, mixing, and tabletting gets product after the packing.
6, the method for preparation compound sheet as claimed in claim 1 or 2 is characterized in that:
(1), with the washing respectively of four kinds of medical materials of Pericarpium Citri Reticulatae, the Radix Aucklandiae, Rhizoma Acori Graminei, Radix Et Rhizoma Rhei, remove impurity, be up to the standards;
(2), Radix Et Rhizoma Rhei, Pericarpium Citri Reticulatae, the Radix Aucklandiae, four kinds of medical material pulverize separately of Rhizoma Acori Graminei are become 40 purpose fine powders, obtain Radix Et Rhizoma Rhei fine powder, Pericarpium Citri Reticulatae fine powder, Radix Aucklandiae fine powder, Rhizoma Acori Graminei fine powder;
(3), sodium bicarbonate, Heavy Magnesium Carbonate, aluminium hydroxide pulverize separately are become fine powder, obtain sodium bicarbonate fine powder, Heavy Magnesium Carbonate fine powder, aluminium hydroxide fine powder;
(4), with Radix Et Rhizoma Rhei fine powder, Pericarpium Citri Reticulatae fine powder, Radix Aucklandiae fine powder, Rhizoma Acori Graminei fine powder, sodium bicarbonate fine powder, Heavy Magnesium Carbonate fine powder, aluminium hydroxide fine powder mix homogeneously, obtain Chinese and Western medicated powder;
(5), with above-mentioned mixed uniform Chinese and Western medicated powder, be ground into superfine powder or nano powder by pulverizer, add starch slurry then, get product after granulation, drying, tabletting, the packing.
CN 03116870 2003-05-09 2003-05-09 Compound chenxiang gastric tablet and preparation process thereof Pending CN1449797A (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101214325B (en) * 2007-12-29 2010-12-08 江西天施康中药股份有限公司 Method for preparing compound 'chenxiangwei'medicine and new use thereof
CN102000179A (en) * 2010-11-09 2011-04-06 承德颈复康药业集团有限公司 New stomachic core coated tablet and preparation method thereof
CN104324090A (en) * 2014-09-28 2015-02-04 江西百神昌诺药业有限公司 Rhubarb total anthraquinone capsule composition
CN115812942A (en) * 2021-09-17 2023-03-21 长春中医药大学 Preparation method of mustard-flavored solid seasoning edible tablets

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101214325B (en) * 2007-12-29 2010-12-08 江西天施康中药股份有限公司 Method for preparing compound 'chenxiangwei'medicine and new use thereof
CN102000179A (en) * 2010-11-09 2011-04-06 承德颈复康药业集团有限公司 New stomachic core coated tablet and preparation method thereof
CN102000179B (en) * 2010-11-09 2012-06-27 承德颈复康药业集团有限公司 New stomachic core coated tablet and preparation method thereof
CN104324090A (en) * 2014-09-28 2015-02-04 江西百神昌诺药业有限公司 Rhubarb total anthraquinone capsule composition
CN104324090B (en) * 2014-09-28 2016-08-24 江西百神昌诺药业有限公司 A kind of general rhubarb anthraquinone capsule composition
CN115812942A (en) * 2021-09-17 2023-03-21 长春中医药大学 Preparation method of mustard-flavored solid seasoning edible tablets

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