CN1686232A - Gynecology restringent - Google Patents
Gynecology restringent Download PDFInfo
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- CN1686232A CN1686232A CN 200510018595 CN200510018595A CN1686232A CN 1686232 A CN1686232 A CN 1686232A CN 200510018595 CN200510018595 CN 200510018595 CN 200510018595 A CN200510018595 A CN 200510018595A CN 1686232 A CN1686232 A CN 1686232A
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- folium callicarpae
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- callicarpae formosanae
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Abstract
An staltic Chinese medicine for treating the gynecological hemorrhage is prepared from beautyberry leaf, small thistle or notoginseng or agrimony, and imperate rhizome or Japanese thistle or sophora flower through proportionally mixing, decocting twice, collecting decoction, vacuum concentrating, spray drying, mixing it with microcrystalline cellulose, and preparing tablets or capsules.
Description
Technical field
The present invention relates to a kind of Chinese medicine hemorrhage that is used for various gynecological bleeding treatments.
Background technology
Gynecological bleeding is a department of obstetrics and gynecology common frdquently encountered disease disease, and the disease of gynecological bleeding can appear in each women in life, and it comprises that hemorrhage, hemorrhage due to placement of IUD of dysfunctional uterine hemorrhage, puerperal and post-abortion, hysteromyoma hemorrhage, inflammation are hemorrhage etc.Use at present and often can only treat at the gynecological bleeding of a certain traditional Chinese medical science type than wide range of therapeutic gynecological bleeding Chinese medicine, general specific aim is not satisfactory.It is hemorrhage that Western medicine hormone therapy " anovulatory dysfunctional uterine hemorrhage " and contraceptive, miscarriage guiding drug rise, and is to correct the endocrine disturbance with control agent internal hormone level, but is difficult to thoroughly solve the root problem that produces imbalance, and the life-time service hormone can produce various side effect simultaneously; Thereby it is very necessary to develop a kind of new Chinese medicine that is used for the treatment of various gynecological bleeding.
Summary of the invention
The object of the present invention is to provide a kind of gynecological Chinese medicine hemorrhage, this medicine composition is reasonable, is applicable to multiple gynecological bleeding, and treatment effective percentage height has no side effect.
In order to realize above-mentioned task, the present invention adopts following technical measures: it comprises Folium Callicarpae Formosanae, Herba Cirsii or Radix Notoginseng or Herba Agrimoniae, Rhizoma Imperatae or Radix Cirsii Japonici or Flos Sophorae, and is all formulated by a certain percentage.
Chinese medicine preparation (part by weight):
Folium Callicarpae Formosanae 65～85%
Herba Cirsii or Radix Notoginseng or Herba Agrimoniae 10～20%
Rhizoma Imperatae or Radix Cirsii Japonici or Flos Sophorae 5～15%
Preparation technology: Chinese medicine is mixed in proportion puts in the extraction pot, add 10 times of water, 100 ℃ of little extraction secondaries that boil, each 145-155 minute, merge secondary raffinate, be evaporated to proportion 1.20 (80 ℃ time), spray drying, 220 ℃ of inlet temperatures, 60 ℃ of outlet temperatures, extract powder, make tablet or capsule after extract powder added microcrystalline Cellulose, tabletting or encapsulating capsule carry out according to a conventional method.Also each raw material can be extracted respectively as stated above, extract each powdered extract powder of back gained, be mixed in proportion and make tablet or capsule after microcrystalline Cellulose is added in the back.
Compound basis: Folium Callicarpae Formosanae is the leaf of Verenaceae xylophyta callicarpa pedunculata callicarpapedunculat R.Br., Folium Callicarpae Macrophyllae C.macrophylla Vahl, Callicarpa kwangtungensis Chun callicarpa Rwangfungensis chun, Callicarpa nudiflora C.nudiflora Hook.etArn., callicarpa cathayana Chang Callicarpa cathayana H.T.chang etc., property hardship, puckery, cool, return liver lung stomach warp, the Bearberry Extract hemostasia effect is usually used in variously going out blood disorder (as spitting of blood, metrorrhagia, hematuria etc.) and being monarch drug; Herba Cirsii, sweet, cool, tool cooling blood for hemostasis effect, Rhizoma Imperatae, sweet, cold, the cool hemostasia effect of tool; This two flavor is made ministerial drug altogether.The effect of full side's Bearberry Extract hemostasis and cooling blood for hemostasis is used for the treatment of various gynecological bleeding.
According to the Chinese medicine gynecological hemostasis sheet that this fills a prescription and preparation technology makes, through acute toxicity test in mice, LD
50〉=5000mg/Kg is more than 500 times of clinical consumption, for reality nontoxic.Preliminary clinical trial, 50 routine various gynecological bleeding patients (comprise dysfunctional uterine hemorrhage, hemorrhage after drug abortion, hemorrhage due to placement of IUD, hysteromyoma hemorrhage, inflammation hemorrhage etc.) are treated, treat through 1-2 the course of treatment (3 days one courses of treatment), total effective rate is 86.3%, does not see the secondary use of any untoward reaction and poison.
The specific embodiment
Embodiment 1:
A kind of gynecologic hemostatic, it is made by the following weight proportion raw material:
Folium Callicarpae Formosanae 65% Herba Cirsii 20% Rhizoma Imperatae 15%
Its preparation process is:
A, the above-mentioned Chinese herbal medicine that meets relevant medical material standard taken by weighing by respectively estimating one's own ability after, mix one and dispose in the rustless steel extraction pot, add 10 times of water (100L water), airtight;
B, heating are heated to 100 ℃ of little boiling and extracted 2 hours, filter, and reclaim filtrate;
C, filtering residue is added 10 times of water (100L water) again, airtight, be heated to 100 ℃ of little boiling, extracted 2 hours, filter;
D, merge secondary filtrate, the filtrate decompression of B and C be concentrated into proportion 1.25 (80 ℃ time), spray drying, dry extract;
E, in dry extract, add the 60g microcrystalline Cellulose, use the one-step-granulating method mixing granulation, 80 ℃ of oven dry, granulate, tabletting, film coating, patent medicine, every weight 0.4g.Usage: every day three times, each 5, three days courses of treatment, be used for a treatment of planting gynecological bleeding.
Embodiment 2:
A kind of gynecologic hemostatic, it is made by the following weight proportion raw material:
Folium Callicarpae Formosanae 85% Radix Notoginseng 10% Rhizoma Imperatae 5%
Preparation process is identical with embodiment 1.
Embodiment 3:
A kind of gynecologic hemostatic, it is made by the following weight proportion raw material:
Folium Callicarpae Formosanae 70% Herba Agrimoniae 15% Radix Cirsii Japonici 15%
Preparation process is identical with embodiment 1.
Embodiment 4:
A kind of gynecologic hemostatic, it is made by the following weight proportion raw material:
Folium Callicarpae Formosanae 80% Herba Cirsii 10% Radix Cirsii Japonici 10%
Preparation process is identical with embodiment 1.
Embodiment 5:
A kind of gynecologic hemostatic, it is made by the following weight proportion raw material:
Folium Callicarpae Formosanae 68% Herba Cirsii 18% Flos Sophorae 14%
Preparation process is identical with embodiment 1.
Embodiment 6:
A kind of gynecologic hemostatic, it is made by the following weight proportion raw material:
Folium Callicarpae Formosanae 72% Radix Notoginseng 16% Flos Sophorae 12%
Preparation process is identical with embodiment 1.
Embodiment 7:
A kind of gynecologic hemostatic, it is made by the following weight proportion raw material:
Folium Callicarpae Formosanae 76% Herba Agrimoniae 12% Radix Cirsii Japonici 12%
Preparation process is identical with embodiment 1.
Embodiment 8:
A kind of gynecologic hemostatic, it is made by the following weight proportion raw material:
Folium Callicarpae Formosanae 82% Radix Notoginseng 11% Radix Cirsii Japonici 7%
Preparation process is identical with embodiment 1.
Embodiment 9:
A kind of gynecologic hemostatic, it is made by the following weight proportion raw material:
Folium Callicarpae Formosanae 70% Herba Cirsii 20% Radix Cirsii Japonici 10%
Preparation process is identical with embodiment 1.
Claims (10)
1, a kind of gynecologic hemostatic, it is made by following materials of weight proportions:
Raw material %
Folium Callicarpae Formosanae 65～85%
Herba Cirsii or Radix Notoginseng or Herba Agrimoniae 10～20%
Rhizoma Imperatae or Radix Cirsii Japonici or Flos Sophorae 5～15%.
2, a kind of gynecologic hemostatic according to claim 1 is characterized in that it is made by the following weight proportion raw material:
Folium Callicarpae Formosanae 65% Herba Cirsii 20% Rhizoma Imperatae 15%.
3, a kind of gynecologic hemostatic according to claim 1 is characterized in that it is made by the following weight proportion raw material:
Folium Callicarpae Formosanae 85% Radix Notoginseng 10% Rhizoma Imperatae 5%.
4, a kind of gynecologic hemostatic according to claim 1 is characterized in that it is made by the following weight proportion raw material:
Folium Callicarpae Formosanae 70% Herba Agrimoniae 15% Radix Cirsii Japonici 15%.
5, a kind of gynecologic hemostatic according to claim 1 is characterized in that it is made by the following weight proportion raw material:
Folium Callicarpae Formosanae 80% Herba Cirsii 10% Radix Cirsii Japonici 10%.
6, a kind of gynecologic hemostatic according to claim 1 is characterized in that it is made by the following weight proportion raw material:
Folium Callicarpae Formosanae 68% Herba Cirsii 18% Flos Sophorae 14%.
7. a kind of gynecologic hemostatic according to claim 1 is characterized in that it is made by the following weight proportion raw material:
Folium Callicarpae Formosanae 72% Radix Notoginseng 16% Flos Sophorae 12%.
8, a kind of gynecologic hemostatic according to claim 1 is characterized in that it is made by the following weight proportion raw material:
Folium Callicarpae Formosanae 76% Herba Agrimoniae 12% Radix Cirsii Japonici 12%.
9, a kind of gynecologic hemostatic according to claim 1 is characterized in that it is made by the following weight proportion raw material:
Folium Callicarpae Formosanae 82% Radix Notoginseng 11% Radix Cirsii Japonici 7%.
10, a kind of gynecologic hemostatic according to claim 1 is characterized in that it is made by the following weight proportion raw material:
Folium Callicarpae Formosanae 70% Herba Cirsii 20% Radix Cirsii Japonici 10%.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2005100185954A CN100348256C (en) | 2005-04-22 | 2005-04-22 | Gynecology restringent |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2005100185954A CN100348256C (en) | 2005-04-22 | 2005-04-22 | Gynecology restringent |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1686232A true CN1686232A (en) | 2005-10-26 |
| CN100348256C CN100348256C (en) | 2007-11-14 |
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ID=35304274
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB2005100185954A Expired - Fee Related CN100348256C (en) | 2005-04-22 | 2005-04-22 | Gynecology restringent |
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| Country | Link |
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| CN (1) | CN100348256C (en) |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007210977A (en) * | 2006-02-13 | 2007-08-23 | Maruzen Pharmaceut Co Ltd | Anti-ageing agent, and slimming agent, and skin cosmetic |
| CN100376277C (en) * | 2005-12-29 | 2008-03-26 | 颜怀伟 | Medicine and food dual purpose Chinese medicine for preventing and treating epistaxis and its manufacturing method |
| CN100376280C (en) * | 2005-12-29 | 2008-03-26 | 颜怀伟 | Medicine and food dual purpose Chinese medicine for blood stanching and its manufacturing method |
| CN100376278C (en) * | 2005-12-29 | 2008-03-26 | 颜怀伟 | Medicine and food dual purpose Chinese medicine for preventing and treating blood ejection and its manufacturing method |
| CN1981840B (en) * | 2005-12-13 | 2010-05-05 | 江西红星药业有限公司 | Chinese-medicinal composition with anti-inflammatory and hemostasis functions and its production |
| CN102772684A (en) * | 2012-07-16 | 2012-11-14 | 梁艳龙 | Traditional Chinese medicinal preparation for treating allergic purpura |
| CN104510694A (en) * | 2013-12-21 | 2015-04-15 | 莫治玲 | Tooth powder for treating gingival bleeding |
| CN107375707A (en) * | 2017-08-04 | 2017-11-24 | 绿都中草药研发中心（北京）有限公司 | A kind of compound quick-acting relieves the pain agent and its application |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1194708C (en) * | 2001-03-27 | 2005-03-30 | 刘文忠 | Process for preparing staltic medicine from Taiwan Beautyberry leaf |
-
2005
- 2005-04-22 CN CNB2005100185954A patent/CN100348256C/en not_active Expired - Fee Related
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1981840B (en) * | 2005-12-13 | 2010-05-05 | 江西红星药业有限公司 | Chinese-medicinal composition with anti-inflammatory and hemostasis functions and its production |
| CN100376277C (en) * | 2005-12-29 | 2008-03-26 | 颜怀伟 | Medicine and food dual purpose Chinese medicine for preventing and treating epistaxis and its manufacturing method |
| CN100376280C (en) * | 2005-12-29 | 2008-03-26 | 颜怀伟 | Medicine and food dual purpose Chinese medicine for blood stanching and its manufacturing method |
| CN100376278C (en) * | 2005-12-29 | 2008-03-26 | 颜怀伟 | Medicine and food dual purpose Chinese medicine for preventing and treating blood ejection and its manufacturing method |
| JP2007210977A (en) * | 2006-02-13 | 2007-08-23 | Maruzen Pharmaceut Co Ltd | Anti-ageing agent, and slimming agent, and skin cosmetic |
| CN102772684A (en) * | 2012-07-16 | 2012-11-14 | 梁艳龙 | Traditional Chinese medicinal preparation for treating allergic purpura |
| CN102772684B (en) * | 2012-07-16 | 2014-01-29 | 梁艳龙 | Traditional Chinese medicinal preparation for treating allergic purpura |
| CN104510694A (en) * | 2013-12-21 | 2015-04-15 | 莫治玲 | Tooth powder for treating gingival bleeding |
| CN107375707A (en) * | 2017-08-04 | 2017-11-24 | 绿都中草药研发中心（北京）有限公司 | A kind of compound quick-acting relieves the pain agent and its application |
Also Published As
| Publication number | Publication date |
|---|---|
| CN100348256C (en) | 2007-11-14 |
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