CN1449439A - 细胞级分包括能分化为神经细胞的细胞 - Google Patents
细胞级分包括能分化为神经细胞的细胞 Download PDFInfo
- Publication number
- CN1449439A CN1449439A CN01813933A CN01813933A CN1449439A CN 1449439 A CN1449439 A CN 1449439A CN 01813933 A CN01813933 A CN 01813933A CN 01813933 A CN01813933 A CN 01813933A CN 1449439 A CN1449439 A CN 1449439A
- Authority
- CN
- China
- Prior art keywords
- cell
- fraction
- medullary
- blood cells
- vertebrates
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0676—Pancreatic cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/48—Reproductive organs
- A61K35/51—Umbilical cord; Umbilical cord blood; Umbilical stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0622—Glial cells, e.g. astrocytes, oligodendrocytes; Schwann cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0663—Bone marrow mesenchymal stem cells (BM-MSC)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0664—Dental pulp stem cells, Dental follicle stem cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0665—Blood-borne mesenchymal stem cells, e.g. from umbilical cord blood
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0666—Mesenchymal stem cells from hair follicles
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0667—Adipose-derived stem cells [ADSC]; Adipose stromal stem cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0668—Mesenchymal stem cells from other natural sources
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/13—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells
- C12N2506/1346—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from mesenchymal stem cells
- C12N2506/1353—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from mesenchymal stem cells from bone marrow mesenchymal stem cells (BM-MSC)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Developmental Biology & Embryology (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Rheumatology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Immunology (AREA)
- Hematology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Psychiatry (AREA)
- Reproductive Health (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
Abstract
Description
Claims (16)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2000190421 | 2000-06-26 | ||
JP190421/2000 | 2000-06-26 | ||
JP160579/2001 | 2001-05-29 | ||
JP2001160579 | 2001-05-29 |
Publications (1)
Publication Number | Publication Date |
---|---|
CN1449439A true CN1449439A (zh) | 2003-10-15 |
Family
ID=26594623
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN01813933A Pending CN1449439A (zh) | 2000-06-26 | 2001-06-26 | 细胞级分包括能分化为神经细胞的细胞 |
Country Status (8)
Country | Link |
---|---|
US (10) | US7098027B2 (zh) |
EP (3) | EP1302534A4 (zh) |
JP (2) | JP4621410B2 (zh) |
KR (2) | KR100947577B1 (zh) |
CN (1) | CN1449439A (zh) |
AU (1) | AU2001274624A1 (zh) |
CA (1) | CA2413910A1 (zh) |
WO (1) | WO2002000849A1 (zh) |
Families Citing this family (68)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2001274624A1 (en) * | 2000-06-26 | 2002-01-08 | Renomedix Institute Inc. | Cell fraction containing cells capable of differentiating into nervous system cells |
ES2522890T3 (es) * | 2000-12-06 | 2014-11-19 | Anthrogenesis Corporation | Método para recolectar células troncales placentarias |
US20040259254A1 (en) * | 2001-10-30 | 2004-12-23 | Osamu Honmou | Method for inducing differentiation mesodermal stem cells, es cells or immortalized cells into nervous system cells |
CN1281739C (zh) * | 2002-02-19 | 2006-10-25 | 美迪宝斯特有限公司 | 从脐带血中分离并扩大培养间充质干细胞/祖细胞及将脐带血来源的间充质干细胞/祖细胞分化成各种间充质组织的方法 |
US20040203142A1 (en) * | 2003-04-14 | 2004-10-14 | Reliance Life Sciences Pvt. Ltd. | Growth of neural precursor cells using umbilical cord blood serum and a process for the preparation thereof for therapeutic purposes |
US20060210544A1 (en) | 2003-06-27 | 2006-09-21 | Renomedix Institute, Inc. | Internally administered therapeutic agents for cranial nerve diseases comprising mesenchymal cells as an active ingredient |
CA2556018A1 (en) * | 2004-02-11 | 2005-09-09 | Aldagen, Inc. | Stem cell populations and methods of use |
JP2007536935A (ja) * | 2004-05-14 | 2007-12-20 | ベクトン・ディキンソン・アンド・カンパニー | 間葉幹細胞の無血清増殖のための細胞培養環境 |
US8017395B2 (en) | 2004-12-17 | 2011-09-13 | Lifescan, Inc. | Seeding cells on porous supports |
WO2006113731A2 (en) * | 2005-04-20 | 2006-10-26 | University Of Florida Research Foundation, Inc. | Bone marrow-derived neurogenic cells and uses thereof |
AU2006202209B2 (en) * | 2005-05-27 | 2011-04-14 | Lifescan, Inc. | Amniotic fluid derived cells |
SI1888123T1 (sl) * | 2005-06-08 | 2013-04-30 | Janssen Biotech, Inc. | Celična terapija za okularno degeneracijo |
US8741643B2 (en) | 2006-04-28 | 2014-06-03 | Lifescan, Inc. | Differentiation of pluripotent stem cells to definitive endoderm lineage |
CN101541954B (zh) * | 2006-11-30 | 2012-12-26 | Medipost株式会社 | 含有人脐带血衍生的间充质干细胞的组合物诱导神经前体细胞或神经干细胞分化和增殖为神经细胞的用途 |
KR20090086260A (ko) * | 2006-12-07 | 2009-08-11 | 테바 파마슈티컬 인더스트리즈 리미티드 | 미손상 골수 또는 미손상 제대 조직으로부터 조직 전구체 세포 및 성숙 조직 세포를 형성 및 증식시키는 방법 |
KR20080068352A (ko) * | 2007-01-19 | 2008-07-23 | 재단법인서울대학교산학협력재단 | 생체외 모델에 의한 신경재생물질 탐색 방법 |
WO2008104065A1 (en) * | 2007-02-26 | 2008-09-04 | Mount Sinai Hospital | Neural cell preparations and methods of making and using them |
US9080145B2 (en) * | 2007-07-01 | 2015-07-14 | Lifescan Corporation | Single pluripotent stem cell culture |
RU2473685C2 (ru) | 2007-07-31 | 2013-01-27 | Лайфскен, Инк. | Дифференцировка человеческих эмбриональных стволовых клеток |
CA2699236C (en) | 2007-09-11 | 2017-02-28 | Sapporo Medical University | Cell growth method and pharmaceutical preparation for tissue repair and regeneration |
CN101878298B (zh) | 2007-11-27 | 2017-08-15 | 生命扫描有限公司 | 人胚胎干细胞的分化 |
CN105886459A (zh) | 2008-02-21 | 2016-08-24 | 詹森生物科技公司 | 用于细胞粘附、培养和分离的方法、表面改性培养板和组合物 |
US8318485B2 (en) * | 2008-02-25 | 2012-11-27 | Natalie Gavrilova | Stem cell therapy for the treatment of diabetic retinopathy and diabetic optic neuropathy |
US8623648B2 (en) | 2008-04-24 | 2014-01-07 | Janssen Biotech, Inc. | Treatment of pluripotent cells |
JP2011526784A (ja) * | 2008-06-30 | 2011-10-20 | セントコア・オーソ・バイオテツク・インコーポレーテツド | 多能性幹細胞の分化 |
KR101829310B1 (ko) | 2008-06-30 | 2018-02-14 | 얀센 바이오테크 인코포레이티드 | 만능 줄기 세포의 분화 |
US20100028307A1 (en) * | 2008-07-31 | 2010-02-04 | O'neil John J | Pluripotent stem cell differentiation |
ES2634445T3 (es) | 2008-10-31 | 2017-09-27 | Janssen Biotech, Inc. | Diferenciación de las células madre embrionarias humanas con el linaje endocrino pancreático |
EP2350265B1 (en) * | 2008-10-31 | 2019-04-17 | Janssen Biotech, Inc. | Differentiation of human embryonic stem cells to the pancreatic endocrine lineage |
KR20100054711A (ko) | 2008-11-14 | 2010-05-25 | 메디포스트(주) | 간엽 줄기세포 또는 이의 배양액을 포함하는 신경질환의 예방 또는 치료용 조성물 |
US20100124781A1 (en) | 2008-11-20 | 2010-05-20 | Shelley Nelson | Pluripotent Stem Cell Culture on Micro-Carriers |
JP5719305B2 (ja) * | 2008-11-20 | 2015-05-13 | ヤンセン バイオテツク,インコーポレーテツド | 平面支持体上での細胞付着及び培養のための方法及び組成物 |
RU2579278C2 (ru) | 2009-07-20 | 2016-04-10 | Янссен Байотек, Инк. | Популяция панкреатических эндокринных клеток-предшественников для снижения концентрации глюкозы в крови и способ дифференцировки панкреатических эндодермальных клеток |
CN102482640B (zh) * | 2009-07-20 | 2015-03-11 | 詹森生物科技公司 | 人胚胎干细胞的分化 |
CN102597219B (zh) * | 2009-07-20 | 2015-08-19 | 詹森生物科技公司 | 人胚胎干细胞的分化 |
JP2013508013A (ja) | 2009-10-16 | 2013-03-07 | ザ ユニバーシティ オブ メディスン アンド デンティストリー オブ ニュー ジャージー | 細胞療法戦略を用いた慢性神経組織損傷の治療方法 |
EP2516626B1 (en) * | 2009-12-23 | 2017-05-10 | Janssen Biotech, Inc. | Differentiation of human embryonic stem cells |
CA2784415C (en) | 2009-12-23 | 2019-06-18 | Jean Xu | Differentiation of human embryonic stem cells |
CN102791851B (zh) | 2010-03-01 | 2017-07-14 | 詹森生物科技公司 | 纯化衍生自多能干细胞的细胞的方法 |
EP3498825A1 (en) | 2010-05-12 | 2019-06-19 | Janssen Biotech, Inc. | Differentiation of human embryonic stem cells |
BR112013004514A2 (pt) | 2010-08-31 | 2016-06-07 | Janssen Biotech Inc | diferenciação das células-tronco embrionárias humanas |
CA2809305C (en) | 2010-08-31 | 2019-06-11 | Janssen Biotech, Inc. | Differentiation of pluripotent stem cells |
SG10201506855RA (en) | 2010-08-31 | 2015-10-29 | Janssen Biotech Inc | Differentiation of human embryonic stem cells |
EP2625263B1 (en) | 2010-10-08 | 2020-03-11 | Terumo BCT, Inc. | Configurable methods and systems of growing and harvesting cells in a hollow fiber bioreactor system |
CN102175501A (zh) * | 2011-01-07 | 2011-09-07 | 山东省农业科学院作物研究所 | 用于显微镜观察的植物样品的前处理方法 |
RU2705001C2 (ru) | 2011-12-22 | 2019-11-01 | Янссен Байотек, Инк. | Дифференцировка эмбриональных стволовых клеток человека в одногормональные инсулинположительные клетки |
EP2823037A4 (en) | 2012-03-07 | 2015-09-16 | Janssen Biotech Inc | DEFINED MEDIA FOR THE EXPANSION AND CARE OF PLURIPOTENTAL STEM CELLS |
AU2013271581B2 (en) | 2012-06-08 | 2018-08-09 | Janssen Biotech, Inc. | Differentiation of human embryonic stem cells into pancreatic endocrine cells |
BR112015015701A2 (pt) | 2012-12-31 | 2017-07-11 | Janssen Biotech Inc | diferenciação de células-tronco embrionárias humanas em células pancreáticas endócrinas com o uso de reguladores hb9 |
US10370644B2 (en) | 2012-12-31 | 2019-08-06 | Janssen Biotech, Inc. | Method for making human pluripotent suspension cultures and cells derived therefrom |
CA2896750A1 (en) | 2012-12-31 | 2014-07-03 | Janssen Biotech, Inc. | Suspension and clustering of human pluripotent cells for differentiation into pancreatic endocrine cells |
WO2014105543A1 (en) | 2012-12-31 | 2014-07-03 | Janssen Biotech, Inc. | Culturing of human embryonic stem cells at the air-liquid interface for differentiation into pancreatic endocrine cells |
EP2977449B1 (en) | 2013-03-21 | 2020-02-26 | Kyoto University | Pluripotent stem cell for neuronal differentiation induction |
WO2015073918A1 (en) | 2013-11-16 | 2015-05-21 | Terumo Bct, Inc. | Expanding cells in a bioreactor |
EP3122866B1 (en) | 2014-03-25 | 2019-11-20 | Terumo BCT, Inc. | Passive replacement of media |
DK3143127T3 (da) | 2014-05-16 | 2021-09-13 | Janssen Biotech Inc | Anvendelse af små molekyler til at forstærke mafa-ekspression i endokrine pankreasceller |
EP3198006B1 (en) | 2014-09-26 | 2021-03-24 | Terumo BCT, Inc. | Scheduled feed |
WO2017004592A1 (en) | 2015-07-02 | 2017-01-05 | Terumo Bct, Inc. | Cell growth with mechanical stimuli |
JP6777840B2 (ja) | 2015-12-25 | 2020-10-28 | 北海道公立大学法人 札幌医科大学 | 脳梗塞の治療用医薬 |
MA45479A (fr) | 2016-04-14 | 2019-02-20 | Janssen Biotech Inc | Différenciation de cellules souches pluripotentes en cellules de l'endoderme de l'intestin moyen |
AU2017258058B2 (en) | 2016-04-28 | 2023-04-13 | Nipro Corporation | Synapse formation agent |
EP3464565A4 (en) | 2016-05-25 | 2020-01-01 | Terumo BCT, Inc. | CELL EXPANSION |
US11685883B2 (en) | 2016-06-07 | 2023-06-27 | Terumo Bct, Inc. | Methods and systems for coating a cell growth surface |
US11104874B2 (en) | 2016-06-07 | 2021-08-31 | Terumo Bct, Inc. | Coating a bioreactor |
EP3656842A1 (en) | 2017-03-31 | 2020-05-27 | Terumo BCT, Inc. | Cell expansion |
US11624046B2 (en) | 2017-03-31 | 2023-04-11 | Terumo Bct, Inc. | Cell expansion |
CA3082368A1 (en) | 2017-11-09 | 2019-05-16 | Sapporo Medical University | Medicine for tissue regeneration, and preparation method therefor |
WO2020162580A1 (ja) | 2019-02-07 | 2020-08-13 | 北海道公立大学法人 札幌医科大学 | ステント内再狭窄の予防のための医薬組成物 |
Family Cites Families (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5108759A (en) * | 1987-04-01 | 1992-04-28 | Ranney David F | Endothelial envelopment drug carriers |
US5197985A (en) * | 1990-11-16 | 1993-03-30 | Caplan Arnold I | Method for enhancing the implantation and differentiation of marrow-derived mesenchymal cells |
US5811094A (en) * | 1990-11-16 | 1998-09-22 | Osiris Therapeutics, Inc. | Connective tissue regeneration using human mesenchymal stem cell preparations |
US5733542A (en) * | 1990-11-16 | 1998-03-31 | Haynesworth; Stephen E. | Enhancing bone marrow engraftment using MSCS |
US5633283A (en) * | 1995-01-23 | 1997-05-27 | Eli Lilly And Company | Method for treating multiple sclerosis |
US6653134B2 (en) * | 1995-03-28 | 2003-11-25 | Cp Hahnemann University | Isolated stromal cells for use in the treatment of diseases of the central nervous system |
US6117633A (en) * | 1995-12-08 | 2000-09-12 | University Technologies International Inc. | DNA sequence encoding the tumor suppressor gene ING1 |
US7189703B2 (en) * | 1998-01-09 | 2007-03-13 | Intracell, Llc | Treatment and diagnosis of alzheimer's disease |
JP2002523085A (ja) * | 1998-08-31 | 2002-07-30 | ニューヨーク・ユニバーシティ | 細胞表面にfgfレセプターを坦持する幹細胞 |
US20020168766A1 (en) | 2000-01-11 | 2002-11-14 | Gold Joseph D. | Genetically altered human pluripotent stem cells |
GB9825948D0 (en) * | 1998-11-26 | 1999-01-20 | Kings College University Of Lo | Diagnosis of spongiform disease |
PT1183035E (pt) | 1999-05-14 | 2015-03-04 | Ford Henry Health System | Transplante de medula óssea para tratamento de acidente vascular cerebral |
US8017112B2 (en) * | 1999-05-14 | 2011-09-13 | Henry Ford Health System | Transplantation of bone marrow stromal cells for treatment of neurodegenerative diseases |
US20050169896A1 (en) * | 1999-05-14 | 2005-08-04 | Henry Ford Health System | Bone marrow transplantation for treatment of stroke |
US20020193301A1 (en) | 1999-08-19 | 2002-12-19 | Stem Cell Pharmaceuticals, Inc. | TGF-alpha polypeptides, functional fragments and methods of use therefor |
US6673606B1 (en) | 2000-04-12 | 2004-01-06 | The Children's Hospital Of Philadelphia | Therapeutic uses for mesenchymal stromal cells |
AU2001274624A1 (en) * | 2000-06-26 | 2002-01-08 | Renomedix Institute Inc. | Cell fraction containing cells capable of differentiating into nervous system cells |
US20020132343A1 (en) | 2001-03-19 | 2002-09-19 | Clark Lum | System and method for delivering umbilical cord-derived tissue-matched stem cells for transplantation |
US20040259254A1 (en) * | 2001-10-30 | 2004-12-23 | Osamu Honmou | Method for inducing differentiation mesodermal stem cells, es cells or immortalized cells into nervous system cells |
WO2003038074A1 (fr) | 2001-10-30 | 2003-05-08 | Renomedix Institute Inc. | Procede d'induction de differenciation de cellules souches de mesoblastes ou de cellules es dans des cellules du systeme nerveux |
US20030161818A1 (en) | 2002-02-25 | 2003-08-28 | Kansas State University Research Foundation | Cultures, products and methods using stem cells |
KR101130220B1 (ko) | 2003-06-27 | 2012-04-13 | 엔씨 메디컬 리서치 가부시키가이샤 | 간엽계 세포를 유효 성분으로 하는 뇌신경 질환 치료용 체내 투여용 약제 |
CN1842339A (zh) * | 2003-06-27 | 2006-10-04 | 株式会社雷诺再生医学研究所 | 含有间叶细胞作为有效成分、治疗脑神经疾病的体内给药治疗剂 |
US20070178591A1 (en) * | 2004-06-25 | 2007-08-02 | Renomedix Institute, Inc | Internally administered therapeutic agents for diseases in central and peripheral nervous system comprising mesenchymal cells as an active ingredient |
-
2001
- 2001-06-26 AU AU2001274624A patent/AU2001274624A1/en not_active Abandoned
- 2001-06-26 CA CA 2413910 patent/CA2413910A1/en not_active Abandoned
- 2001-06-26 CN CN01813933A patent/CN1449439A/zh active Pending
- 2001-06-26 EP EP01941254A patent/EP1302534A4/en not_active Ceased
- 2001-06-26 EP EP20100180002 patent/EP2292735A1/en not_active Ceased
- 2001-06-26 WO PCT/JP2001/005456 patent/WO2002000849A1/ja active Application Filing
- 2001-06-26 JP JP2002505965A patent/JP4621410B2/ja not_active Expired - Lifetime
- 2001-06-26 EP EP20100179989 patent/EP2295539A1/en not_active Withdrawn
- 2001-06-26 KR KR1020097024992A patent/KR100947577B1/ko active IP Right Grant
-
2002
- 2002-12-23 US US10/330,963 patent/US7098027B2/en not_active Expired - Lifetime
- 2002-12-26 KR KR20027017743A patent/KR100947576B1/ko active IP Right Grant
-
2005
- 2005-07-26 US US11/189,050 patent/US20050282276A1/en not_active Abandoned
-
2008
- 2008-03-13 US US12/076,092 patent/US20080248004A1/en not_active Abandoned
-
2010
- 2010-08-12 JP JP2010180888A patent/JP4782237B2/ja not_active Expired - Lifetime
-
2011
- 2011-03-04 US US13/040,954 patent/US20110158967A1/en not_active Abandoned
-
2012
- 2012-05-25 US US13/481,308 patent/US20120237946A1/en not_active Abandoned
- 2012-05-25 US US13/481,180 patent/US9115344B2/en not_active Expired - Fee Related
- 2012-05-25 US US13/481,416 patent/US20120230961A1/en not_active Abandoned
- 2012-05-25 US US13/481,318 patent/US20120237487A1/en not_active Abandoned
-
2013
- 2013-01-02 US US13/733,008 patent/US20130195808A1/en not_active Abandoned
-
2015
- 2015-05-28 US US14/723,514 patent/US10640749B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US20110158967A1 (en) | 2011-06-30 |
AU2001274624A1 (en) | 2002-01-08 |
JP2010260873A (ja) | 2010-11-18 |
CA2413910A1 (en) | 2002-12-27 |
US20080248004A1 (en) | 2008-10-09 |
US20120237486A1 (en) | 2012-09-20 |
US20130195808A1 (en) | 2013-08-01 |
US20150337265A1 (en) | 2015-11-26 |
US20050282276A1 (en) | 2005-12-22 |
JPWO2002000849A1 (ja) | 2004-03-04 |
US10640749B2 (en) | 2020-05-05 |
KR100947576B1 (ko) | 2010-03-15 |
EP1302534A4 (en) | 2004-06-16 |
KR100947577B1 (ko) | 2010-03-15 |
US20120237946A1 (en) | 2012-09-20 |
US20120230961A1 (en) | 2012-09-13 |
US20040121461A1 (en) | 2004-06-24 |
KR20090131682A (ko) | 2009-12-29 |
EP2292735A1 (en) | 2011-03-09 |
JP4782237B2 (ja) | 2011-09-28 |
KR20030032973A (ko) | 2003-04-26 |
EP1302534A1 (en) | 2003-04-16 |
JP4621410B2 (ja) | 2011-01-26 |
EP2295539A1 (en) | 2011-03-16 |
US20120237487A1 (en) | 2012-09-20 |
US9115344B2 (en) | 2015-08-25 |
WO2002000849A1 (fr) | 2002-01-03 |
US7098027B2 (en) | 2006-08-29 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN1449439A (zh) | 细胞级分包括能分化为神经细胞的细胞 | |
Hu et al. | Repair of extended peripheral nerve lesions in rhesus monkeys using acellular allogenic nerve grafts implanted with autologous mesenchymal stem cells | |
Kisiel et al. | Isolation, characterization, and in vitro proliferation of canine mesenchymal stem cells derived from bone marrow, adipose tissue, muscle, and periosteum | |
US7897388B2 (en) | Growth of neural precursor cells using umbilical cord blood serum and a process for the preparation for therapeutic purposes | |
US20070243172A1 (en) | Multipotent stem cells derived from placenta tissue and cellular therapeutic agents comprising the same | |
Brehm et al. | Stem cell-based tissue engineering in veterinary orthopaedics | |
CN108456657B (zh) | 犬脐带间充质干细胞及其制备方法和冻存方法 | |
Ribitsch et al. | Basic science and clinical application of stem cells in veterinary medicine | |
Mohammadi et al. | Effects of undifferentiated cultured omental adipose-derived stem cells on peripheral nerve regeneration | |
CN109893541B (zh) | 经血干细胞来源的外泌体在制备治疗宫腔粘连的药物中的应用 | |
KR101389851B1 (ko) | 신경능선줄기세포의 배양방법 및 그 용도 | |
DE102009041885B4 (de) | Separation von Mesenchymalen Stammzellen | |
WO2013139952A2 (de) | Neue msc-oberflächenmarker | |
US20240091269A1 (en) | Treatment of bipolar disorder using mesenchymal stem cells and modification of mesenchymal stem cells | |
US20020100065A1 (en) | Production of typed human cells, tissues and organs | |
KR101984167B1 (ko) | 중간엽 줄기세포의 분리방법 | |
Anderson et al. | Keynote Lectures | |
Yan et al. | Recent progress in the differentiation of bone marrow derived mesenchymal stem cells (BMMSCs) to cardiomyocyte-like cells and their clinical application | |
Montzka | An investigation into the characteristics and potential therapeutic application of human bone marrow-derived mesenchymal stromal cells in experimental spinal cord injury | |
JP2000083655A (ja) | シュワン細胞の純粋培養方法 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
ASS | Succession or assignment of patent right |
Owner name: DIGUOZANGQI PHARMACEUTICAL CO., LTD.; MITSUI SUMI Effective date: 20040218 |
|
C41 | Transfer of patent application or patent right or utility model | ||
TA01 | Transfer of patent application right |
Effective date of registration: 20040218 Address after: Hokkaido Japan Applicant after: Renomedix Inst Inc. Co-applicant after: Imperial organ Pharmaceutical Co., Ltd. Co-applicant after: Mitsui Sumitomo Marine Protection Network Co., Ltd. Co-applicant after: Co., Ltd. Hitachi Co., Ltd. Address before: Hokkaido Japan Applicant before: Renomedix Inst Inc. |
|
C12 | Rejection of a patent application after its publication | ||
RJ01 | Rejection of invention patent application after publication |