CN1435214A - Compound body-strengthening eucommia bark mixture for treating diseases caused by kidney Qi deficiency - Google Patents
Compound body-strengthening eucommia bark mixture for treating diseases caused by kidney Qi deficiency Download PDFInfo
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- CN1435214A CN1435214A CN 02127913 CN02127913A CN1435214A CN 1435214 A CN1435214 A CN 1435214A CN 02127913 CN02127913 CN 02127913 CN 02127913 A CN02127913 A CN 02127913A CN 1435214 A CN1435214 A CN 1435214A
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- CN
- China
- Prior art keywords
- filtrate
- radix ginseng
- deficiency
- kidney
- hours
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000007812 deficiency Effects 0.000 title claims abstract description 11
- 201000010099 disease Diseases 0.000 title claims abstract description 9
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title claims abstract description 9
- 210000003734 kidney Anatomy 0.000 title claims abstract description 9
- 241000208688 Eucommia Species 0.000 title claims abstract description 6
- 239000000203 mixture Substances 0.000 title claims abstract description 6
- 150000001875 compounds Chemical class 0.000 title claims description 5
- 238000005728 strengthening Methods 0.000 title claims description 5
- 241000208340 Araliaceae Species 0.000 claims abstract description 19
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 claims abstract description 19
- 235000003140 Panax quinquefolius Nutrition 0.000 claims abstract description 19
- 239000003814 drug Substances 0.000 claims abstract description 19
- 235000008434 ginseng Nutrition 0.000 claims abstract description 19
- 239000007788 liquid Substances 0.000 claims description 21
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 20
- 239000000706 filtrate Substances 0.000 claims description 16
- 229940079593 drug Drugs 0.000 claims description 12
- 238000004321 preservation Methods 0.000 claims description 12
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 12
- WXMKPNITSTVMEF-UHFFFAOYSA-M sodium benzoate Chemical compound [Na+].[O-]C(=O)C1=CC=CC=C1 WXMKPNITSTVMEF-UHFFFAOYSA-M 0.000 claims description 9
- 235000010234 sodium benzoate Nutrition 0.000 claims description 9
- 239000004299 sodium benzoate Substances 0.000 claims description 9
- 239000006228 supernatant Substances 0.000 claims description 8
- 239000012153 distilled water Substances 0.000 claims description 7
- 241000411851 herbal medicine Species 0.000 claims description 5
- 239000000047 product Substances 0.000 claims description 5
- 230000006837 decompression Effects 0.000 claims description 4
- 238000004821 distillation Methods 0.000 claims description 4
- 238000001914 filtration Methods 0.000 claims description 4
- 239000000796 flavoring agent Substances 0.000 claims description 4
- 235000019634 flavors Nutrition 0.000 claims description 4
- 238000000034 method Methods 0.000 claims description 4
- 239000002244 precipitate Substances 0.000 claims description 4
- 238000003825 pressing Methods 0.000 claims description 4
- 102000004169 proteins and genes Human genes 0.000 claims description 4
- 108090000623 proteins and genes Proteins 0.000 claims description 4
- 238000004064 recycling Methods 0.000 claims description 4
- 238000001256 steam distillation Methods 0.000 claims description 4
- 238000003756 stirring Methods 0.000 claims description 4
- 230000000694 effects Effects 0.000 abstract description 7
- 206010061428 decreased appetite Diseases 0.000 abstract description 2
- 231100000331 toxic Toxicity 0.000 abstract description 2
- 230000002588 toxic effect Effects 0.000 abstract description 2
- 208000022531 anorexia Diseases 0.000 abstract 1
- 206010027175 memory impairment Diseases 0.000 abstract 1
- 229940088597 hormone Drugs 0.000 description 3
- 239000005556 hormone Substances 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 231100000957 no side effect Toxicity 0.000 description 2
- 230000001737 promoting effect Effects 0.000 description 2
- 208000000059 Dyspnea Diseases 0.000 description 1
- 206010013975 Dyspnoeas Diseases 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 230000001914 calming effect Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 238000010791 quenching Methods 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 238000007670 refining Methods 0.000 description 1
- 208000013220 shortness of breath Diseases 0.000 description 1
- 230000035922 thirst Effects 0.000 description 1
- 239000011800 void material Substances 0.000 description 1
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- Medicines Containing Plant Substances (AREA)
Abstract
A Chinese medicine in the form of mixture for treating diseases caused by deficiency of kidney Qi, such as body weakness, anorexia, hypomnesia, etc., is prepared from ginseng and eucommia bark. Its advantages are high curative effect, no toxic by-effect and low cost.
Description
Technical field:
The present invention relates to a kind of compound body-strengthening eucommia bark mixture, belong to the technical field of pharmaceuticals for the treatment of diseases caused by kidney Qi deficiency.
Background technology:
At present, the medicine that is used for the treatment of diseases caused by kidney Qi deficiency in the prior art is a lot, these medicines generally all have certain curative effect effect, but medicine exists and contains hormone, bad, the price problem of higher of mouthfeel mostly, and some medicine also exists certain toxic and side effects, takes not too safe problem.
Summary of the invention:
The objective of the invention is: provide a kind of curative effect better, not contain the compound body-strengthening eucommia bark mixture that any hormone, mouthfeel are good, have no side effect, take safe ready, treatment diseases caused by kidney Qi deficiency that cost of manufacture is lower, to overcome the deficiency of existing medicine.
The present invention is achieved in that it is mainly made by Radix Ginseng and the Cortex Eucommiae two flavor Chinese herbal medicine, each Chinese herbal medicine of distinguishing the flavor of is respectively by weight ratio: 24～36 parts of Radix Ginsengs, 62～96 parts of the Cortexs Eucommiae, its method for making is: with Cortex Eucommiae shredding, with Radix Ginseng section back steam distillation, press 3～3.5 times of the Radix Ginseng total amount and collect distillates, and add it by every 100ml distillate and measure behind 2 ‰ the sodium benzoate standby 5 ℃ of following cold preservations; Medicine residues of Radix Ginseng after the distillation is added in the Cortex Eucommiae silk, water by 4～5 times of amounts of its total amount adding decocts 2～4 times then, each 2～3 hours, decoction liquor is filtered to get filtrate with 200 eye mesh screens, it is 1.08 under 80 ℃ temperature that filtrate is concentrated into relative density, ethanol to the concentration of alcohol that adds 95% concentration then is 65% ± 2%, after spending the night, placement draws supernatant, with its precipitate centrifugal get rid of after the filter filtrate, this filtrate and supernatant merging are condensed into behind decompression recycling ethanol and 1: 1 concentrated solution of crude drug in whole recipe quantity again, the concentrated liquid measure of pressing gained then adds 2～4 times distilled water, again it is boiled and put cold back in 3 minutes and extraordinarily go into sodium benzoate by 1.64% of former concentrated liquid measure, take out after 48 hours 5 ℃ of following cold preservations then and get medicinal liquid with plate-and-frame filtration, 10% protein sugar solution will be contained then and extraordinarily into the liquidly medicinal liquid must be merged by 1.82 of crude drug in whole recipe quantity, to merge medicinal liquid again boils, put cold after, add the standby distillate that makes, after stirring 5 ℃ of following cold preservations 48 hours, take out and filter, add distilled water 9.09 times, after embedding, get product to primary dose.
Owing to adopted technique scheme, the present invention compares with the medicine of existing treatment diseases caused by kidney Qi deficiency, the present invention adopts is that the Chinese herbal medicine of common pure natural is that raw material forms through refining, it has that tonify deficiency is set upright, strong waist is calmed the nerves, the effect of promoting the production of body fluid to quench thirst, the mind calming and mentality promoting, can be used for shortness of breath and tired spirit, kidney Qi deficiency, the treatment of diseases such as body void, inappetence, hypomnesis, uneasy sleeping at night after being ill.The present invention have curative effect better, do not contain any hormone, mouthfeel good, have no side effect, take safe ready, advantage that cost of manufacture is low.
The specific embodiment:
Embodiments of the invention 1: get Radix Ginseng 24 grams, the Cortex Eucommiae 62 grams, Cortex Eucommiae shredding is standby, with Radix Ginseng section back steam distillation, press 3～3.5 times of the Radix Ginseng total amount and collect its distillate, and add its ratio of measuring 2 ‰ sodium benzoate amount in every 100ml distillate and add sodium benzoate, then that it is standby 5 ℃ of following cold preservations; Medicine residues of Radix Ginseng after the distillation is added in the Cortex Eucommiae silk, water by 4～5 times of amounts of its total amount adding decocts 2～4 times then, each 2～3 hours, decoction liquor is filtered to get filtrate with 200 eye mesh screens, it is 1.08 under 80 ℃ temperature that filtrate is concentrated into relative density, ethanol to the concentration of alcohol that adds 95% concentration then is 65% ± 2%, after spending the night, placement draws supernatant, with its precipitate centrifugal get rid of after the filter filtrate, this filtrate and supernatant merging are condensed into behind decompression recycling ethanol and 1: 1 concentrated solution of crude drug in whole recipe quantity again, the concentrated liquid measure of pressing gained then adds 2～4 times distilled water, again it is boiled and put cold back in 3 minutes and extraordinarily go into sodium benzoate by 1.64% of former concentrated liquid measure, take out after 48 hours 5 ℃ of following cold preservations then and get medicinal liquid with plate-and-frame filtration, 10% protein sugar solution will be contained then and extraordinarily into the liquidly medicinal liquid must be merged by 1.82 of crude drug in whole recipe quantity, to merge medicinal liquid again boils, put cold after, add the standby distillate that makes, after stirring 5 ℃ of following cold preservations 48 hours, take out and filter, add distilled water 9.09 times, after embedding, get product to primary dose.
Embodiments of the invention 2: get Radix Ginseng 36 grams, the Cortex Eucommiae 96 grams, its method for making is identical with embodiment 1.
Embodiments of the invention 3: get Radix Ginseng 30 grams, the Cortex Eucommiae 80 grams, Cortex Eucommiae shredding is standby, steam distillation is used in Radix Ginseng section back, collect its distillate 100ml, in distillate, add it and measure 2 ‰ sodium benzoate, then that it is standby 5 ℃ of following cold preservations; Medicine residues of Radix Ginseng after the distillation is added in the Cortex Eucommiae silk, water by 4～5 times of amounts of its total amount adding decocts 2～4 times then, each 2～3 hours, decoction liquor is filtered to get filtrate with 200 eye mesh screens, it is 1.08 under 80 ℃ temperature that filtrate is concentrated into relative density, ethanol to the concentration of alcohol that adds 95% concentration then is 65% ± 2%, after spending the night, placement draws supernatant, with its precipitate centrifugal get rid of after the filter filtrate, this filtrate and supernatant merging are condensed into behind decompression recycling ethanol and the about 110ml of 1: 1 concentrated solution of crude drug in whole recipe quantity again, the concentrated liquid measure adding distil water of pressing gained then is to 500ml, it was boiled 3 minutes and put cold back and extraordinarily go into sodium benzoate by 1.64% of former concentrated liquid measure, take out after 48 hours 5 ℃ of following cold preservations then and get medicinal liquid with plate-and-frame filtration, to contain 10% protein sugar solution, 200 grams then adds in the medicinal liquids and must merge medicinal liquid, to merge medicinal liquid again boils, put cold after, add the standby distillate that makes, after stirring 5 ℃ of following cold preservations 48 hours, take out and filter, add distilled water to 1000ml, by getting product after every bottle of 100ml or every 10ml embedding.
The usage of its finished product and consumption are: oral, and every day 2～3 times, each 10ml.
Claims (1)
1, a kind of compound body-strengthening eucommia bark mixture for the treatment of diseases caused by kidney Qi deficiency, it is characterized in that: it is mainly made by Radix Ginseng and the Cortex Eucommiae two flavor Chinese herbal medicine, each Chinese herbal medicine of distinguishing the flavor of is respectively by weight ratio: 24～36 parts of Radix Ginsengs, 62～96 parts of the Cortexs Eucommiae, its method for making is: with Cortex Eucommiae shredding, with Radix Ginseng section back steam distillation, press 3～3.5 times of the Radix Ginseng total amount and collect distillates, and add it by every 100ml distillate and measure behind 2 ‰ the sodium benzoate standby 5 ℃ of following cold preservations; Medicine residues of Radix Ginseng after the distillation is added in the Cortex Eucommiae silk, water by 4～5 times of amounts of its total amount adding decocts 2～4 times then, each 2～3 hours, decoction liquor is filtered to get filtrate with 200 eye mesh screens, it is 1.08 under 80 ℃ temperature that filtrate is concentrated into relative density, ethanol to the concentration of alcohol that adds 95% concentration then is 65% ± 2%, after spending the night, placement draws supernatant, with its precipitate centrifugal get rid of after the filter filtrate, this filtrate and supernatant merging are condensed into behind decompression recycling ethanol and 1: 1 concentrated solution of crude drug in whole recipe quantity again, the concentrated liquid measure of pressing gained then adds 2～4 times distilled water, again it is boiled and put cold back in 3 minutes and extraordinarily go into sodium benzoate by 1.64% of former concentrated liquid measure, take out after 48 hours 5 ℃ of following cold preservations then and get medicinal liquid with plate-and-frame filtration, 10% protein sugar solution will be contained then and extraordinarily into the liquidly medicinal liquid must be merged by 1.82 of crude drug in whole recipe quantity, to merge medicinal liquid again boils, put cold after, add the standby distillate that makes, after stirring 5 ℃ of following cold preservations 48 hours, take out and filter, add distilled water 9.09 times, after embedding, get product to primary dose.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB021279136A CN1165333C (en) | 2002-11-28 | 2002-11-28 | Compound body-strengthening eucommia bark mixture for treating diseases caused by kidney Qi deficiency |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB021279136A CN1165333C (en) | 2002-11-28 | 2002-11-28 | Compound body-strengthening eucommia bark mixture for treating diseases caused by kidney Qi deficiency |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1435214A true CN1435214A (en) | 2003-08-13 |
| CN1165333C CN1165333C (en) | 2004-09-08 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB021279136A Expired - Lifetime CN1165333C (en) | 2002-11-28 | 2002-11-28 | Compound body-strengthening eucommia bark mixture for treating diseases caused by kidney Qi deficiency |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1165333C (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112957424A (en) * | 2021-03-09 | 2021-06-15 | 陕西省万寿制药有限责任公司 | Composition for improving physical performance of human body |
-
2002
- 2002-11-28 CN CNB021279136A patent/CN1165333C/en not_active Expired - Lifetime
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112957424A (en) * | 2021-03-09 | 2021-06-15 | 陕西省万寿制药有限责任公司 | Composition for improving physical performance of human body |
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| Publication number | Publication date |
|---|---|
| CN1165333C (en) | 2004-09-08 |
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| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20190403 Address after: 550029 Jinyang Science and Technology Industrial Park, Guiyang High-tech Industrial Development Zone, Guizhou Province (No. 11 Duyun Road) Patentee after: HANFANG PHARMA CO.,LTD. Address before: 550001 No. 13 Jiuhua Road, Guiyang City, Guizhou Province Patentee before: Guiyang Dechangxiang Pharmaceutical Co.,Ltd. |
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| TR01 | Transfer of patent right | ||
| PE01 | Entry into force of the registration of the contract for pledge of patent right | ||
| PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: Compound body-strengthening eucommia bark mixture for treating diseases caused by kidney Qi deficiency Effective date of registration: 20200519 Granted publication date: 20040908 Pledgee: Guizhou mingdekang Technology Center (L.P.) Pledgor: HANFANG PHARMA Co.,Ltd. Registration number: Y2020520000006 |
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| PC01 | Cancellation of the registration of the contract for pledge of patent right | ||
| PC01 | Cancellation of the registration of the contract for pledge of patent right |
Date of cancellation: 20220428 Granted publication date: 20040908 Pledgee: Guizhou mingdekang Technology Center (L.P.) Pledgor: HANFANG PHARMA CO.,LTD. Registration number: Y2020520000006 |
|
| CX01 | Expiry of patent term | ||
| CX01 | Expiry of patent term |
Granted publication date: 20040908 |