CN1427699A - 补充的囊内晶状体及其植入方法 - Google Patents
补充的囊内晶状体及其植入方法 Download PDFInfo
- Publication number
- CN1427699A CN1427699A CN01809211A CN01809211A CN1427699A CN 1427699 A CN1427699 A CN 1427699A CN 01809211 A CN01809211 A CN 01809211A CN 01809211 A CN01809211 A CN 01809211A CN 1427699 A CN1427699 A CN 1427699A
- Authority
- CN
- China
- Prior art keywords
- secl
- polymer
- phacocyst
- crystalline lens
- eyes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 title claims abstract description 94
- 238000002513 implantation Methods 0.000 title description 10
- 210000000695 crystalline len Anatomy 0.000 claims abstract description 179
- 239000002775 capsule Substances 0.000 claims abstract description 107
- 229920000642 polymer Polymers 0.000 claims abstract description 81
- 208000014733 refractive error Diseases 0.000 claims abstract description 55
- 208000029091 Refraction disease Diseases 0.000 claims abstract description 22
- 230000004430 ametropia Effects 0.000 claims abstract description 22
- 210000001508 eye Anatomy 0.000 claims description 108
- 239000000499 gel Substances 0.000 claims description 71
- 239000000463 material Substances 0.000 claims description 39
- 239000007788 liquid Substances 0.000 claims description 35
- 230000001105 regulatory effect Effects 0.000 claims description 29
- 230000004075 alteration Effects 0.000 claims description 25
- 230000008569 process Effects 0.000 claims description 21
- -1 siloxanes Chemical group 0.000 claims description 20
- 230000008859 change Effects 0.000 claims description 16
- 239000002994 raw material Substances 0.000 claims description 12
- 230000003321 amplification Effects 0.000 claims description 11
- 238000002372 labelling Methods 0.000 claims description 11
- 238000003199 nucleic acid amplification method Methods 0.000 claims description 11
- 230000000694 effects Effects 0.000 claims description 10
- 230000004438 eyesight Effects 0.000 claims description 9
- 239000000017 hydrogel Substances 0.000 claims description 9
- VVQNEPGJFQJSBK-UHFFFAOYSA-N Methyl methacrylate Chemical compound COC(=O)C(C)=C VVQNEPGJFQJSBK-UHFFFAOYSA-N 0.000 claims description 8
- 239000002981 blocking agent Substances 0.000 claims description 8
- 230000001965 increasing effect Effects 0.000 claims description 8
- ILZXXGLGJZQLTR-UHFFFAOYSA-N 2-phenylethyl 2-methylprop-2-enoate Chemical compound CC(=C)C(=O)OCCC1=CC=CC=C1 ILZXXGLGJZQLTR-UHFFFAOYSA-N 0.000 claims description 7
- HPSGLFKWHYAKSF-UHFFFAOYSA-N 2-phenylethyl prop-2-enoate Chemical compound C=CC(=O)OCCC1=CC=CC=C1 HPSGLFKWHYAKSF-UHFFFAOYSA-N 0.000 claims description 7
- WOBHKFSMXKNTIM-UHFFFAOYSA-N Hydroxyethyl methacrylate Chemical compound CC(=C)C(=O)OCCO WOBHKFSMXKNTIM-UHFFFAOYSA-N 0.000 claims description 7
- SUPCQIBBMFXVTL-UHFFFAOYSA-N ethyl 2-methylprop-2-enoate Chemical compound CCOC(=O)C(C)=C SUPCQIBBMFXVTL-UHFFFAOYSA-N 0.000 claims description 7
- 238000005096 rolling process Methods 0.000 claims description 6
- 239000000203 mixture Substances 0.000 claims description 5
- 238000007906 compression Methods 0.000 claims description 4
- 230000006835 compression Effects 0.000 claims description 4
- 230000002708 enhancing effect Effects 0.000 claims description 3
- 238000003780 insertion Methods 0.000 claims description 2
- 230000037431 insertion Effects 0.000 claims description 2
- 239000003795 chemical substances by application Substances 0.000 claims 5
- 239000003086 colorant Substances 0.000 claims 4
- 230000010354 integration Effects 0.000 claims 4
- 230000036040 emmetropia Effects 0.000 claims 2
- 230000004308 accommodation Effects 0.000 abstract description 23
- 238000001356 surgical procedure Methods 0.000 abstract description 10
- 239000013589 supplement Substances 0.000 abstract 1
- 230000000153 supplemental effect Effects 0.000 abstract 1
- 238000012937 correction Methods 0.000 description 31
- 230000003287 optical effect Effects 0.000 description 30
- 238000013461 design Methods 0.000 description 24
- 210000001525 retina Anatomy 0.000 description 23
- 208000001491 myopia Diseases 0.000 description 13
- 238000002347 injection Methods 0.000 description 11
- 239000007924 injection Substances 0.000 description 11
- 210000001747 pupil Anatomy 0.000 description 11
- 230000000007 visual effect Effects 0.000 description 11
- 201000010041 presbyopia Diseases 0.000 description 10
- 239000007943 implant Substances 0.000 description 9
- 208000002177 Cataract Diseases 0.000 description 8
- 210000002159 anterior chamber Anatomy 0.000 description 8
- 230000009286 beneficial effect Effects 0.000 description 8
- 230000001886 ciliary effect Effects 0.000 description 8
- 210000004087 cornea Anatomy 0.000 description 8
- 239000000835 fiber Substances 0.000 description 8
- 239000011521 glass Substances 0.000 description 8
- 210000000554 iris Anatomy 0.000 description 8
- 238000011049 filling Methods 0.000 description 7
- 230000008901 benefit Effects 0.000 description 6
- 238000006116 polymerization reaction Methods 0.000 description 6
- 206010020675 Hypermetropia Diseases 0.000 description 5
- 230000004305 hyperopia Effects 0.000 description 5
- 201000006318 hyperopia Diseases 0.000 description 5
- 230000004379 myopia Effects 0.000 description 5
- 210000004027 cell Anatomy 0.000 description 4
- 150000001875 compounds Chemical class 0.000 description 4
- 210000003205 muscle Anatomy 0.000 description 4
- 238000003825 pressing Methods 0.000 description 4
- 238000011084 recovery Methods 0.000 description 4
- 210000001519 tissue Anatomy 0.000 description 4
- 201000009487 Amblyopia Diseases 0.000 description 3
- 241000459479 Capsula Species 0.000 description 3
- 238000013459 approach Methods 0.000 description 3
- 210000001742 aqueous humor Anatomy 0.000 description 3
- 230000006378 damage Effects 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- 238000011065 in-situ storage Methods 0.000 description 3
- 230000005865 ionizing radiation Effects 0.000 description 3
- 230000009467 reduction Effects 0.000 description 3
- 210000003786 sclera Anatomy 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 238000011282 treatment Methods 0.000 description 3
- 102000008186 Collagen Human genes 0.000 description 2
- 108010035532 Collagen Proteins 0.000 description 2
- 206010061218 Inflammation Diseases 0.000 description 2
- 241001465754 Metazoa Species 0.000 description 2
- SBKRTALNRRAOJP-BWSIXKJUSA-N N-[(2S)-4-amino-1-[[(2S,3R)-1-[[(2S)-4-amino-1-oxo-1-[[(3S,6S,9S,12S,15R,18R,21S)-6,9,18-tris(2-aminoethyl)-15-benzyl-3-[(1R)-1-hydroxyethyl]-12-(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclotricos-21-yl]amino]butan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxobutan-2-yl]-6-methylheptanamide (6S)-N-[(2S)-4-amino-1-[[(2S,3R)-1-[[(2S)-4-amino-1-oxo-1-[[(3S,6S,9S,12S,15R,18R,21S)-6,9,18-tris(2-aminoethyl)-15-benzyl-3-[(1R)-1-hydroxyethyl]-12-(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclotricos-21-yl]amino]butan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxobutan-2-yl]-6-methyloctanamide sulfuric acid Chemical compound OS(O)(=O)=O.CC(C)CCCCC(=O)N[C@@H](CCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCN)C(=O)N[C@H]1CCNC(=O)[C@@H](NC(=O)[C@H](CCN)NC(=O)[C@H](CCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](CCN)NC1=O)[C@@H](C)O.CC[C@H](C)CCCCC(=O)N[C@@H](CCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCN)C(=O)N[C@H]1CCNC(=O)[C@@H](NC(=O)[C@H](CCN)NC(=O)[C@H](CCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](CCN)NC1=O)[C@@H](C)O SBKRTALNRRAOJP-BWSIXKJUSA-N 0.000 description 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 2
- 239000000654 additive Substances 0.000 description 2
- 230000004888 barrier function Effects 0.000 description 2
- 229920001436 collagen Polymers 0.000 description 2
- 230000003750 conditioning effect Effects 0.000 description 2
- 230000008602 contraction Effects 0.000 description 2
- 230000002950 deficient Effects 0.000 description 2
- 238000012217 deletion Methods 0.000 description 2
- 230000037430 deletion Effects 0.000 description 2
- 210000000871 endothelium corneal Anatomy 0.000 description 2
- 210000004247 hand Anatomy 0.000 description 2
- 238000007654 immersion Methods 0.000 description 2
- 230000004054 inflammatory process Effects 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- 210000003141 lower extremity Anatomy 0.000 description 2
- 230000014759 maintenance of location Effects 0.000 description 2
- 238000005259 measurement Methods 0.000 description 2
- 210000000056 organ Anatomy 0.000 description 2
- 239000001301 oxygen Substances 0.000 description 2
- 229910052760 oxygen Inorganic materials 0.000 description 2
- 229920001296 polysiloxane Polymers 0.000 description 2
- 238000012545 processing Methods 0.000 description 2
- 230000002040 relaxant effect Effects 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 230000002207 retinal effect Effects 0.000 description 2
- 239000003190 viscoelastic substance Substances 0.000 description 2
- JJCZGVLYNIVKKD-UHFFFAOYSA-N 3-hydroxy-2-phenylpropanamide Chemical compound NC(=O)C(CO)C1=CC=CC=C1 JJCZGVLYNIVKKD-UHFFFAOYSA-N 0.000 description 1
- HRPVXLWXLXDGHG-UHFFFAOYSA-N Acrylamide Chemical compound NC(=O)C=C HRPVXLWXLXDGHG-UHFFFAOYSA-N 0.000 description 1
- 206010002091 Anaesthesia Diseases 0.000 description 1
- 208000008516 Capsule Opacification Diseases 0.000 description 1
- 241001212149 Cathetus Species 0.000 description 1
- 206010011033 Corneal oedema Diseases 0.000 description 1
- 208000035126 Facies Diseases 0.000 description 1
- 208000005422 Foreign-Body reaction Diseases 0.000 description 1
- 208000010412 Glaucoma Diseases 0.000 description 1
- 102000003886 Glycoproteins Human genes 0.000 description 1
- 108090000288 Glycoproteins Proteins 0.000 description 1
- 229920002683 Glycosaminoglycan Polymers 0.000 description 1
- 229930193140 Neomycin Natural products 0.000 description 1
- 239000004677 Nylon Substances 0.000 description 1
- 241000283973 Oryctolagus cuniculus Species 0.000 description 1
- 108010093965 Polymyxin B Proteins 0.000 description 1
- 206010058046 Post procedural complication Diseases 0.000 description 1
- 208000035965 Postoperative Complications Diseases 0.000 description 1
- 229910000831 Steel Inorganic materials 0.000 description 1
- 206010047513 Vision blurred Diseases 0.000 description 1
- 206010047571 Visual impairment Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- HOBWAPHTEJGALG-JKCMADFCSA-N [(1r,5s)-8-methyl-8-azoniabicyclo[3.2.1]octan-3-yl] 3-hydroxy-2-phenylpropanoate;sulfate Chemical compound [O-]S([O-])(=O)=O.C([C@H]1CC[C@@H](C2)[NH+]1C)C2OC(=O)C(CO)C1=CC=CC=C1.C([C@H]1CC[C@@H](C2)[NH+]1C)C2OC(=O)C(CO)C1=CC=CC=C1 HOBWAPHTEJGALG-JKCMADFCSA-N 0.000 description 1
- NOSIYYJFMPDDSA-UHFFFAOYSA-N acepromazine Chemical compound C1=C(C(C)=O)C=C2N(CCCN(C)C)C3=CC=CC=C3SC2=C1 NOSIYYJFMPDDSA-UHFFFAOYSA-N 0.000 description 1
- 229960005054 acepromazine Drugs 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- 229910021529 ammonia Inorganic materials 0.000 description 1
- 230000037005 anaesthesia Effects 0.000 description 1
- 230000008485 antagonism Effects 0.000 description 1
- 230000002927 anti-mitotic effect Effects 0.000 description 1
- 238000003491 array Methods 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 201000009310 astigmatism Diseases 0.000 description 1
- 229960002028 atropine sulfate Drugs 0.000 description 1
- 230000003190 augmentative effect Effects 0.000 description 1
- 239000003855 balanced salt solution Substances 0.000 description 1
- 210000002469 basement membrane Anatomy 0.000 description 1
- 230000006399 behavior Effects 0.000 description 1
- 230000002146 bilateral effect Effects 0.000 description 1
- 239000011230 binding agent Substances 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 239000013043 chemical agent Substances 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 238000002512 chemotherapy Methods 0.000 description 1
- 210000003161 choroid Anatomy 0.000 description 1
- 238000012790 confirmation Methods 0.000 description 1
- 238000007596 consolidation process Methods 0.000 description 1
- 230000001276 controlling effect Effects 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 201000004778 corneal edema Diseases 0.000 description 1
- 238000004132 cross linking Methods 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000000280 densification Methods 0.000 description 1
- 230000000916 dilatatory effect Effects 0.000 description 1
- 239000004205 dimethyl polysiloxane Substances 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000006073 displacement reaction Methods 0.000 description 1
- 239000000839 emulsion Substances 0.000 description 1
- 210000000981 epithelium Anatomy 0.000 description 1
- 238000005530 etching Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 210000000744 eyelid Anatomy 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 210000001650 focal adhesion Anatomy 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 230000005484 gravity Effects 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 230000036571 hydration Effects 0.000 description 1
- 238000006703 hydration reaction Methods 0.000 description 1
- 206010020718 hyperplasia Diseases 0.000 description 1
- 239000000815 hypotonic solution Substances 0.000 description 1
- 238000005286 illumination Methods 0.000 description 1
- 230000000266 injurious effect Effects 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 230000004410 intraocular pressure Effects 0.000 description 1
- 201000004614 iritis Diseases 0.000 description 1
- 210000001660 lens cortex crystalline Anatomy 0.000 description 1
- 208000029515 lens disease Diseases 0.000 description 1
- 210000001542 lens epithelial cell Anatomy 0.000 description 1
- 210000003664 lens nucleus crystalline Anatomy 0.000 description 1
- 210000003041 ligament Anatomy 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 210000004379 membrane Anatomy 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 230000004118 muscle contraction Effects 0.000 description 1
- 229960004927 neomycin Drugs 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 229920001778 nylon Polymers 0.000 description 1
- 210000001328 optic nerve Anatomy 0.000 description 1
- 125000005375 organosiloxane group Chemical group 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 230000002085 persistent effect Effects 0.000 description 1
- 239000002831 pharmacologic agent Substances 0.000 description 1
- 230000000704 physical effect Effects 0.000 description 1
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 description 1
- 229920002492 poly(sulfone) Polymers 0.000 description 1
- 229920002401 polyacrylamide Polymers 0.000 description 1
- 230000002980 postoperative effect Effects 0.000 description 1
- 239000002243 precursor Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 230000002285 radioactive effect Effects 0.000 description 1
- 238000009256 replacement therapy Methods 0.000 description 1
- 238000010008 shearing Methods 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- 238000004088 simulation Methods 0.000 description 1
- 239000008279 sol Substances 0.000 description 1
- 238000007711 solidification Methods 0.000 description 1
- 230000008023 solidification Effects 0.000 description 1
- 238000000527 sonication Methods 0.000 description 1
- 230000003595 spectral effect Effects 0.000 description 1
- 238000010561 standard procedure Methods 0.000 description 1
- 230000003068 static effect Effects 0.000 description 1
- 239000010959 steel Substances 0.000 description 1
- 230000035882 stress Effects 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 238000011477 surgical intervention Methods 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 239000012780 transparent material Substances 0.000 description 1
- 239000011345 viscous material Substances 0.000 description 1
- 230000009978 visual deterioration Effects 0.000 description 1
- 210000004127 vitreous body Anatomy 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- BPICBUSOMSTKRF-UHFFFAOYSA-N xylazine Chemical compound CC1=CC=CC(C)=C1NC1=NCCCS1 BPICBUSOMSTKRF-UHFFFAOYSA-N 0.000 description 1
- 229960001600 xylazine Drugs 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
- A61F2/16—Intraocular lenses
- A61F2/1613—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
- A61F2/16—Intraocular lenses
- A61F2/1613—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
- A61F2/1637—Correcting aberrations caused by inhomogeneities; correcting intrinsic aberrations, e.g. of the cornea, of the surface of the natural lens, aspheric, cylindrical, toric lenses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
- A61F2/16—Intraocular lenses
- A61F2/1613—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
- A61F2/1624—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus having adjustable focus; power activated variable focus means, e.g. mechanically or electrically by the ciliary muscle or from the outside
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2210/0085—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof hardenable in situ, e.g. epoxy resins
Landscapes
- Health & Medical Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Surgery (AREA)
- Prostheses (AREA)
- Eyeglasses (AREA)
- Materials For Medical Uses (AREA)
- Non-Portable Lighting Devices Or Systems Thereof (AREA)
- Optical Couplings Of Light Guides (AREA)
- Developing Agents For Electrophotography (AREA)
- Electrochromic Elements, Electrophoresis, Or Variable Reflection Or Absorption Elements (AREA)
Abstract
Description
参数 | 优选的规格范围 | 更优选的规格范围 | 最优选的规格范围 |
总(触觉感受器)的直径a | 9.0mm-10.5mm | 9.5mm-10mm | 调节后的直径 |
触觉感受器的厚度 | 0.01-0.1mm | 0.01-0.05mm | 0.01-0.02mm |
光带的尺寸b | 4.5mm-9.5mm | 6.0mm-9.0mm | 7.5mm-8.5mm |
光学Young’s系数c | 0.1KPa-10KPa | 0.5Kpa-1Kpa | 与聚合物凝胶相同 |
触觉感受器Young’s系数 | 0.1KPa-20KPa | 0.5KPa-1.5Kpa | 与聚合物凝胶相同 |
光学的屈光指数d | 1.2-1.8 | 1.3-1.75 | 1.33-1.67 |
IR传送e | 80%-100%(1060nm-1100nm) | 80%-100%(1060nm-1100nm) | 85%-98%(1060nm-1100nm) |
UV传送 | <5% | <2% | <0.5% |
Claims (62)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US20261000P | 2000-05-09 | 2000-05-09 | |
US60/202,610 | 2000-05-09 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1427699A true CN1427699A (zh) | 2003-07-02 |
CN1208031C CN1208031C (zh) | 2005-06-29 |
Family
ID=22750582
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CNB01809211XA Expired - Fee Related CN1208031C (zh) | 2000-05-09 | 2001-05-08 | 补充的囊内晶状体及其植入方法 |
Country Status (12)
Country | Link |
---|---|
EP (1) | EP1299051B1 (zh) |
JP (1) | JP3940295B2 (zh) |
CN (1) | CN1208031C (zh) |
AT (1) | ATE358460T1 (zh) |
AU (2) | AU2001259602B2 (zh) |
CA (1) | CA2409769C (zh) |
DE (1) | DE60127676T2 (zh) |
DK (1) | DK1299051T3 (zh) |
ES (1) | ES2284647T3 (zh) |
NZ (1) | NZ522145A (zh) |
PT (1) | PT1299051E (zh) |
WO (1) | WO2001085067A2 (zh) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101568312B (zh) * | 2006-12-13 | 2013-08-21 | 爱克透镜国际公司 | 带有可变修正功能的可调节人工晶状体 |
CN110621261A (zh) * | 2017-03-13 | 2019-12-27 | 凯亚可公司 | 调节性晶状体装置 |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20070129800A1 (en) * | 2005-12-07 | 2007-06-07 | C&C Vision International Limited | Hydrolic accommodating intraocular lens |
CN1985781B (zh) * | 2005-12-20 | 2010-10-13 | 视达日本有限公司 | 眼内插入用晶状体的插入器具 |
US8439974B2 (en) * | 2006-05-03 | 2013-05-14 | Vision Crc Limited | Adjusted index of refraction of ocular replacement material |
GB2468367B (en) | 2009-05-27 | 2011-02-16 | See Again Europ Ltd | Intraocular lens systems and methods |
MX339355B (es) * | 2011-05-23 | 2016-05-18 | Univ Southern California | Acomodación de lente intraocular. |
EP3375410A1 (en) * | 2017-03-13 | 2018-09-19 | Kejako Sa | Accommodative lens device |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1330951C (en) * | 1987-07-06 | 1994-07-26 | Stanley H. Pine | Synthetic polymer for endocapsular lens replacement |
US5326347A (en) * | 1991-08-12 | 1994-07-05 | Cumming J Stuart | Intraocular implants |
US6048364A (en) * | 1998-06-20 | 2000-04-11 | Skottun; Bernt Christian | Highly deformable intraocular lens and method for inserting same into an eye |
-
2001
- 2001-05-08 AU AU2001259602A patent/AU2001259602B2/en not_active Ceased
- 2001-05-08 ES ES01933156T patent/ES2284647T3/es not_active Expired - Lifetime
- 2001-05-08 CA CA002409769A patent/CA2409769C/en not_active Expired - Fee Related
- 2001-05-08 NZ NZ522145A patent/NZ522145A/en not_active IP Right Cessation
- 2001-05-08 EP EP01933156A patent/EP1299051B1/en not_active Expired - Lifetime
- 2001-05-08 DK DK01933156T patent/DK1299051T3/da active
- 2001-05-08 DE DE60127676T patent/DE60127676T2/de not_active Expired - Lifetime
- 2001-05-08 AU AU5960201A patent/AU5960201A/xx active Pending
- 2001-05-08 AT AT01933156T patent/ATE358460T1/de active
- 2001-05-08 PT PT01933156T patent/PT1299051E/pt unknown
- 2001-05-08 JP JP2001581725A patent/JP3940295B2/ja not_active Expired - Fee Related
- 2001-05-08 WO PCT/US2001/014728 patent/WO2001085067A2/en active IP Right Grant
- 2001-05-08 CN CNB01809211XA patent/CN1208031C/zh not_active Expired - Fee Related
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101568312B (zh) * | 2006-12-13 | 2013-08-21 | 爱克透镜国际公司 | 带有可变修正功能的可调节人工晶状体 |
CN110621261A (zh) * | 2017-03-13 | 2019-12-27 | 凯亚可公司 | 调节性晶状体装置 |
Also Published As
Publication number | Publication date |
---|---|
PT1299051E (pt) | 2007-06-27 |
AU2001259602B2 (en) | 2005-09-08 |
ES2284647T3 (es) | 2007-11-16 |
DE60127676T2 (de) | 2008-04-03 |
JP2003532491A (ja) | 2003-11-05 |
DK1299051T3 (da) | 2007-08-06 |
AU5960201A (en) | 2001-11-20 |
JP3940295B2 (ja) | 2007-07-04 |
ATE358460T1 (de) | 2007-04-15 |
EP1299051A2 (en) | 2003-04-09 |
CA2409769C (en) | 2007-01-09 |
CN1208031C (zh) | 2005-06-29 |
WO2001085067A2 (en) | 2001-11-15 |
EP1299051B1 (en) | 2007-04-04 |
NZ522145A (en) | 2005-01-28 |
CA2409769A1 (en) | 2001-11-15 |
WO2001085067A3 (en) | 2002-03-28 |
DE60127676D1 (de) | 2007-05-16 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JP2020022791A (ja) | プロテーゼ水晶体嚢およびその挿入方法 | |
US7060095B2 (en) | Supplementary endo-capsular lens and method of implantation | |
US20050107873A1 (en) | Accommodative intraocular lens and method of implantation | |
US20070021832A1 (en) | Foldable intraocular lens with adaptable haptics | |
US20080086208A1 (en) | Foldable Intraocular Lens With Adaptable Haptics | |
CN101039635A (zh) | 具有可适应触觉件的可折叠的眼内透镜 | |
WO2005058203A1 (en) | Multi-focal intraocular lens, and method for making and using same | |
JP2009532176A (ja) | 遠近調節を備えた眼内レンズ | |
US20090319039A1 (en) | Method in Eye Surgery | |
WO2008131282A2 (en) | Biomechanical design of intracorneal inlays | |
US20100262234A1 (en) | Posterior chamber phakic intraocular lens | |
JP2012512668A (ja) | 能力を改良するために1つ又は複数の強膜プロテーゼを備えた、人工眼内レンズ、変造された生来の水晶体、又は再充填された生来の水晶体嚢 | |
JP2020526235A (ja) | 眼鏡なしの調節レンズ | |
CN1208031C (zh) | 补充的囊内晶状体及其植入方法 | |
JP4339704B2 (ja) | 安定な前眼房フェイキックレンズ | |
AU2001259602A1 (en) | Supplementary endo-capsular lens and method of implantation | |
Kumari et al. | Intra ocular lens technology—a review of journey from its inception | |
US20030204253A1 (en) | Posterior chamber phakic lens | |
US10555806B2 (en) | Method and device for optimizing vision via customization of spherical aberration of eye | |
CN112043459A (zh) | 人工晶状体与用于优化焦深和视野周边图像质量的方法 | |
RU2080839C1 (ru) | Искусственный хрусталик глаза | |
Alío et al. | Shape-changing IOLs: NuLens | |
NZ532781A (en) | Supplementary endo-capsular lens and method of implantation | |
WO2018172553A1 (en) | Intracorneal implant | |
McNeil | A look into the IOL space |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
ASS | Succession or assignment of patent right |
Owner name: VISION CRC LTD. Free format text: FORMER OWNER: NEWSOUTH INNOVATIONS PTY LTD. Effective date: 20140612 |
|
C41 | Transfer of patent application or patent right or utility model | ||
C56 | Change in the name or address of the patentee |
Owner name: NEWSOUTH INNOVATIONS PTY LTD. Free format text: FORMER NAME: UNISEARCH LTD. |
|
CP01 | Change in the name or title of a patent holder |
Address after: New South Wales, Australia Patentee after: NEWSOUTH INNOVATIONS Pty Ltd. Address before: New South Wales, Australia Patentee before: Unisearch Ltd. |
|
TR01 | Transfer of patent right |
Effective date of registration: 20140612 Address after: New South Wales, Australia Patentee after: VISION CRC Ltd. Address before: New South Wales, Australia Patentee before: Newsouth Innovations Pty Ltd. |
|
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20050629 Termination date: 20170508 |
|
CF01 | Termination of patent right due to non-payment of annual fee |