CN1413723A - Method for extracting medicine from bluish dogbane - Google Patents
Method for extracting medicine from bluish dogbane Download PDFInfo
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- CN1413723A CN1413723A CN 02135798 CN02135798A CN1413723A CN 1413723 A CN1413723 A CN 1413723A CN 02135798 CN02135798 CN 02135798 CN 02135798 A CN02135798 A CN 02135798A CN 1413723 A CN1413723 A CN 1413723A
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- medicine
- apocyni veneti
- herba apocyni
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Abstract
The application of kendir in preparing medicines is disclosed, which features that it can be used in conjuction of 4 Chinese-medicinal materials including cassia seed, cordyceps, etc to prepare antihypertenssive medicine, or 3 ones including fleece flower root, red sgae root, etc to prepare hypolipemic medicine, or 4 ones including American ginseng, wolfberry fruit, etc to prepare the medicine for preventing vascular infarction, or 3 ones including wolfberry fruit, cassia seed, etc to prepare calcmingm edicine, or 3 ones including prunella spike, cassia seed, etc to prepare antisanility medicine.
Description
One, technical field: the invention discloses the method for producing medicine series with Herba Apocyni veneti.
Two, background technology: Herba Apocyni veneti is the traditional Chinese crude drug of China, has the effect of heat clearing away, suppressing the hyperactive liver, tranquilizing by nourishing the heart, inducing diuresis to remove edema.Be used for dizziness due to hyperactivity of liver-YANG, palpitation and insomnia, edema oliguria, diseases such as hypertension, neurasthenia, nephritis edema.Modern medicine study shows: the root of Herba Apocyni veneti, stem, leaf contain isoquercitrin, plain, globulariacitrin, and several amino acids, organic acid, sterol, steroid saponin is former and the effective ingredient of triterpene substance.In recent years, people were developing, are utilizing aspects such as Herba Apocyni veneti production health beverage and health product to attempt, but the research and development of Herba Apocyni veneti medical value also is in blank.
Three, summary of the invention: purpose of the present invention is exactly the pharmacological property at Herba Apocyni veneti, the exploitation medicine series.
Technical scheme of the present invention is to utilize to contain isoquercitrin, plain, globulariacitrin in the root of Herba Apocyni veneti, stem, the leaf, several amino acids, organic acid, sterol, steroid saponin is former and the effective ingredient of triterpene substance, cooperates the medicine of producing different efficacies with other Chinese herbal medicine.Specifically comprise: behind (1) and Semen Cassiae, Cordyceps, Fructus Lycii, the Fructus Alpiniae Oxyphyllae compatibility, refine the medicine of Fructus Alpiniae Oxyphyllae the kidney invigorating; (2) with the Radix Polygoni Multiflori, Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong compatibility after, refine the medicine of invigorating kidney, promoting blood circulation; (3) with Radix Panacis Quinquefolii, Fructus Lycii, the Radix Astragali, Radix Salviae Miltiorrhizae compatibility after, refine the medicine of benefiting QI for activating blood circulation; (4) with Fructus Lycii, yellow Rui, Semen Cassiae compatibility after, refine the medicine of enriching yin boost qi; (5) with Spica Prunellae, Semen Cassiae, Flos Chrysanthemi Indici compatibility after, refine the medicine of removing heat from the liver to lower the high blood pressure.
Adopt the medicine of such scheme preparation to have (1) hypotensive effect, (2) but blood fat reducing, (3) prevention blood vessel infraction, (4) tranquillizing and allaying excitement, (5) anti-aging effects.
Four, description of drawings: do not have.
Five, the specific embodiment:
Embodiment 1: get the 40-60 weight portion, behind Semen Cassiae, Cordyceps, Fructus Lycii, each 10-15 part compatibility of Fructus Alpiniae Oxyphyllae, carry out steaming and decocting, refinement, be processed into oral liquid or capsule then.This medicine has the effect of Fructus Alpiniae Oxyphyllae the kidney invigorating.
Embodiment 2: get Herba Apocyni veneti 40-60 weight portion, behind the Radix Polygoni Multiflori, Radix Salviae Miltiorrhizae, each 15-20 part compatibility of Rhizoma Chuanxiong, the medicine of refinement has the effect of invigorating kidney, promoting blood circulation.
Embodiment 3: get Herba Apocyni veneti 40-60 weight portion, behind Radix Panacis Quinquefolii, Fructus Lycii, the Radix Astragali, each 10-15 part compatibility of Radix Salviae Miltiorrhizae, the medicine of refinement has the effect of benefiting QI for activating blood circulation.
Embodiment 4: get Herba Apocyni veneti 40-60 weight portion, behind Fructus Lycii, yellow Rui, each 10-20 part compatibility of Semen Cassiae, the medicine of refinement has the effect of enriching yin boost qi.
Embodiment 5: get Herba Apocyni veneti 40-60 weight portion, behind Spica Prunellae, Semen Cassiae, each 15-20 part compatibility of Flos Chrysanthemi Indici, the medicine of refinement has the effect of removing heat from the liver to lower the high blood pressure.
Herba Apocyni veneti in the foregoing description comprises one or more mixing of Herba Apocyni veneti cured leaf, root or stem.Using the Herba Apocyni veneti cured leaf need complete, dry the back uses.
Do further narration below in conjunction with the foregoing description with regard to the pharmacological action of Herba Apocyni veneti:
1, to the heart effect.The root of Apocynum venetum L. decoct has cardiotonic, and the laboratory animal heart contraction is obviously strengthened, and is similar to the strophantin K effect, and can make the animal decreased heart rate.Root of Apocynum venetum L. decoct or Herba Apocyni veneti cardiotonic glycoside can slightly increase coronary artery blood volume and myocardial oxygen consumption, poacynum hendersonii woodson leaf extract through the animal intravenous injection, can increase cardiac output of stroke volume, improve left heart function, make tiny arteriectasia, resistance descends, and showing has regulating action to the tip blood circulation.
2, hypotensive effect: the Folium Apocyni Veneti decoct shows through zoopery: obvious and stable hypotensive effect is arranged; But the root of Apocynum venetum L. decoct then makes the laboratory animal blood pressure slightly raise.Folium Apocyni Veneti does not reduce normal arterial pressure, to blood pressure person on the low side, can also play the regulating action of boosting.Poacynum hendersonii woodson leaf extractum extract is better than Herba Apocyni veneti extractum.And renal hypertension is obvious and persistent hypotensive effect.Also have effect for reducing blood fat in addition, be suitable for the senile hypertension patient especially.
3, to the effect of blood system: the aprocynum henderson hook extract, can make that whole blood is sticking highly obviously to descend, showing that poacynum hendersonii woodson leaf has improves the sticking high effect of blood; Platelet aggregation there is inhibitory action.Preventing and treating platelet aggregation clinically, reduce thrombosis, is the important step of prevention cardiovascular and cerebrovascularinfarction disease.
4, the effect of raise immunity.The Herba Apocyni veneti extractum, zoopery shows immunologic function influential, can significantly alleviate of the atrophy effect of immunosuppressant cyclophosphamide to animal spleen, prompting may increase immunologic function and strengthen the effect of macrophage phagocytic function under immunity of organism suppresses, and can obvious potentiation be arranged to humoral immune function.
5, tranquilizing effect: though Herba Apocyni veneti extractum animal drugs can make the animal spontaneous activity obviously reduce after 30 minutes, it is more obvious to increase situation with dosage.
6, anti-aging effects: 1% dogbane leaf extractive has function in delaying senility, can make life span of drosophila melanogaster on average prolong 9.35-13.95%.And can in various degree reduction effect be arranged to the brown matter content of pluck.Feeding silkworm with the Folium Mori of 10% Folium Apocyni Veneti extractum dipping can make silkworm prolong 3.86-5.1% entire life respectively; Make mice mean survival time (MST) prolongation.Liver of age groups mice and the superoxide dismutase of heart (SOD) vigor are generally risen, it can suppress lipid peroxidation and the damage of free basis, thereby improve HDL-e (high density lipoprotein), this is useful to preventing and treating arteriosclerosis, thereby plays delaying senility function.
Other effect: smooth muscle is had inhibitory action, and root of Apocynum venetum L. has diuresis, and function of relieving cough and calming asthma is arranged; The hemophilus influenza rhinovirus there is the obvious suppression effect.
Herba Apocyni veneti is the new drug that developed recently gets up, sweet and slightly bitter taste, and cold nature has stronger heating suppressing the hyperactive liver, the merit of blood pressure lowering, for controlling hypertension product commonly used.This product has effects such as heart tonifying diuresis, blood fat reducing, reduction blood viscosity, is used for the treatment of heart failure and all kinds of edema thereof, hyperlipemia, blood viscosity rising etc. again and all obtains better curative effect.Especially to preventing and treating arteriosclerosis, the prevention cardiovascular and cerebrovascular disease is rather important.Enhance immunity, defying age are still arranged in addition and anti-ly cure cold, tracheitis etc.
Claims (5)
1, produces the method for medicine with Herba Apocyni veneti, it is characterized in that: utilize in the root, stem, leaf of Herba Apocyni veneti to contain isoquercitrin, plain, globulariacitrin, several amino acids, organic acid, sterol, steroid saponin is former and the effective ingredient of triterpene substance, behind Semen Cassiae, Cordyceps, Fructus Lycii, Fructus Alpiniae Oxyphyllae compatibility, refine the medicine of Fructus Alpiniae Oxyphyllae the kidney invigorating.
2, produce the method for medicine with Herba Apocyni veneti, it is characterized in that: utilize in the root, stem, leaf of Herba Apocyni veneti to contain isoquercitrin, plain, globulariacitrin, several amino acids, organic acid, sterol, steroid saponin is former and the effective ingredient of triterpene substance, behind the Radix Polygoni Multiflori, Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong compatibility, refine the medicine of invigorating kidney, promoting blood circulation.
3, produce the method for medicine with Herba Apocyni veneti, it is characterized in that: utilize in the root, stem, leaf of Herba Apocyni veneti to contain isoquercitrin, plain, globulariacitrin, several amino acids, organic acid, sterol, steroid saponin is former and the effective ingredient of triterpene substance, behind Radix Panacis Quinquefolii, Fructus Lycii, the Radix Astragali, Radix Salviae Miltiorrhizae compatibility, refine the medicine of benefiting QI for activating blood circulation.
4, produce the method for medicine with Herba Apocyni veneti, it is characterized in that: utilize in the root, stem, leaf of Herba Apocyni veneti to contain isoquercitrin, plain, globulariacitrin, several amino acids, organic acid, sterol, steroid saponin is former and the effective ingredient of triterpene substance, behind Fructus Lycii, yellow Rui, Semen Cassiae compatibility, refine the medicine of enriching yin boost qi.
5, produce the method for medicine with Herba Apocyni veneti, it is characterized in that: utilize in the root, stem, leaf of Herba Apocyni veneti to contain isoquercitrin, plain, globulariacitrin, several amino acids, organic acid, sterol, steroid saponin is former and the effective ingredient of triterpene substance, behind Spica Prunellae, Semen Cassiae, Flos Chrysanthemi Indici compatibility, refine the medicine of removing heat from the liver to lower the high blood pressure.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 02135798 CN1413723A (en) | 2002-11-18 | 2002-11-18 | Method for extracting medicine from bluish dogbane |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 02135798 CN1413723A (en) | 2002-11-18 | 2002-11-18 | Method for extracting medicine from bluish dogbane |
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| CN1413723A true CN1413723A (en) | 2003-04-30 |
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| CN 02135798 Pending CN1413723A (en) | 2002-11-18 | 2002-11-18 | Method for extracting medicine from bluish dogbane |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105255696A (en) * | 2015-11-07 | 2016-01-20 | 宁静 | Vinegar capable of lowering blood pressure and losing weight |
| CN109954021A (en) * | 2017-12-14 | 2019-07-02 | 神威药业集团有限公司 | It is a kind of with adjust blood pressure and the composition of function of relaxing bowel and preparation method thereof |
-
2002
- 2002-11-18 CN CN 02135798 patent/CN1413723A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105255696A (en) * | 2015-11-07 | 2016-01-20 | 宁静 | Vinegar capable of lowering blood pressure and losing weight |
| CN109954021A (en) * | 2017-12-14 | 2019-07-02 | 神威药业集团有限公司 | It is a kind of with adjust blood pressure and the composition of function of relaxing bowel and preparation method thereof |
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| C06 | Publication | ||
| PB01 | Publication | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |