CN1413606A

CN1413606A - Medicine for treatment of hepatitis

Info

Publication number: CN1413606A
Application number: CN 01136762
Authority: CN
Inventors: 邓大勇
Original assignee: Individual
Current assignee: Individual
Priority date: 2001-10-24
Filing date: 2001-10-24
Publication date: 2003-04-30

Abstract

A Chinese medicine in the form of powder, capsule, or tablet for treating hepatitides, cirrhosis, alcoholic liver, etc is prepared from 35 Chinese-medicinal materials including pangolin scales, turtle shell, green chiretta, red sage root, etc. Its advantages are high curative effect and no toxic by-effect.

Description

A kind of medicine for the treatment of hepatopathy

The present invention relates to a kind of medicine for the treatment of hepatopathy.Specifically a kind of is the medicine that feedstock production becomes with the Chinese herbal medicine.

China is viral hepatitis district occurred frequently in the world, and according to disease surveillance report in 1991, China's viral hepatitis sickness rate was 175.94/10 ten thousand people.Only wherein asymptomatic HbsAg carrier estimates just to have people more than 100,000,000.Having proved all has popularly in other various hepatitis of China, also have other virus, and medicine, and the hepatopathy due to the ethanol etc. is increasing.Because primary disease is very harmful to people ' s health, country has dropped into great amount of manpower and material resources for this reason, has also obtained certain achievement, but because the viral hepatitis complicated clinical manifestation, the scholar differs to its understanding.Dialectical treatment randomness is bigger, thereby a kind of existing extensive curative effect of extremely long-pending exploitation, and safety has no side effect again, and the medicine of cheap treatment hepatopathy, is a urgent task.

The object of the present invention is to provide a kind of connection side's Chinese patent medicine with extensive treatment hepatopathy.Be subjected to medical condition and economic condition to treating the deficiency of hepatopathy to remedy the patient.

Technical scheme pharmaceutical formulation of the present invention is than being substantially: Squama Manis 15g, Radix Paeoniae Rubra 15g, Radix Curcumae 15g, Radix Notoginseng 15g, Radix Astragali 20g, Rhizoma Atractylodis Macrocephalae 15g, Radix Paeoniae Alba 15g, Radix Salviae Miltiorrhizae 20g, Carapax Trionycis 20g, Fructus Crataegi 20g, Rhizoma Acori Graminei 15g, Cortex Moutan 15g, Semen Persicae 15g, Fructus Forsythiae 20g, eupolyphage sece steleophaga 15g, Herba Patriniae 20g, Herba Andrographis 20g, Herba Hyperici Japonici 20g, mountain mast 15g, Radix Codonopsis 15g, Herba Artemisiae Scopariae 20g, Radix Angelicae Sinensis 20g, Radix Scutellariae 15g, Cortex Magnoliae Officinalis 15g, Radix Gentianae 15g, Rhizoma Osmundae 15g, Os Draconis 20g, Concha Ostreae 20g, Rhizoma Cyperi 15g, Herba Eupatorii 15g, Rhizoma Dioscoreae 15g, Rhizoma Curcumae 15g, Matrii Sulfas Exsiccatus 10～15g, Semen Pruni 10g, Beishan Mountain Radix Sophorae Tonkinensis 15g.

Its optimum formula ratio is: Squama Manis 15～10g, Radix Paeoniae Rubra 12g, Radix Curcumae 15g, Radix Notoginseng 15～18g, Radix Astragali 20g, the Rhizoma Atractylodis Macrocephalae 15～18g, Radix Paeoniae Alba 15g, Radix Salviae Miltiorrhizae 15～25g, Carapax Trionycis 20～30g, Fructus Crataegi 15～20g, Rhizoma Acori Graminei 12g, Cortex Moutan 15g, Semen Persicae 10～15g, Fructus Forsythiae 20g, eupolyphage sece steleophaga 10～15g, Herba Patriniae 15～20g, Herba Andrographis 20～30g, Herba Hyperici Japonici 20～30g, mountain mast 15g, Radix Codonopsis 15g, Herba Artemisiae Scopariae 30g, Radix Angelicae Sinensis 15～20g, Radix Scutellariae 15～18g, Cortex Magnoliae Officinalis 10～15g, Radix Gentianae 15g, Rhizoma Osmundae 15g, Os Draconis 20g, Concha Ostreae 20g, Rhizoma Cyperi 10g, Herba Eupatorii 15g, Rhizoma Dioscoreae 15g, Rhizoma Curcumae 15g, Matrii Sulfas Exsiccatus 10～15g, Semen Pruni 15g, Beishan Mountain Radix Sophorae Tonkinensis 15g.

The present invention prepares process for above-mentioned 30 five tastes Chinese herbal medicine, gets the raw materials ready by square proportioning, breaks into 120 order fine powders, and is encapsulated, or tabletting, gets final product through conventional disinfection by ultraviolet light, also can directly take powder.

Solution of the present invention is: according to motherland's traditional medicine hepatopathy is used the dialectical Analyses that " the four methods of diagnosis and eight key links " makes body pathogenesis state on macroscopic view, and in conjunction with using the objective of modern science, check, from tissue, cell and the more profound micro-variations that goes up the reflection pathomorphism, deepened essence understanding to disease, and in conjunction with Chinese medicine, pharmacology is chosen: Squama Manis, Radix Polygoni Ciliinerve, Radix Curcumae, Radix Notoginseng, Rhizoma Curcumae, Radix Salviae Miltiorrhizae, Semen Persicae, Radix Angelicae Sinensis, eupolyphage sece steleophaga share, and it has the function of blood circulation promoting and blood stasis dispelling, consumer product dredge stasis, promoting the function of the gallbladder to alleviate jaundice.The modern pharmacology effect: said medicine has the protection liver glycogen; eliminate hepatosplenomegaly; reduce the hepatocellular degeneration necrosis; promote functions such as liver cell regeneration; yellow cowherb, the Rhizoma Atractylodis Macrocephalae, the Radix Paeoniae Alba, Radix Codonopsis, Rhizoma Dioscoreae, Fructus Crataegi compatibility; have invigorating the spleen and regulating the stomach, the effect of strengthening vital QI to eliminate pathogenic factors has demonstrated fully the whole principle that the liver spleen is ruled together.The modern pharmacology master is bright: the above-mentioned acute and chronic liver injury that prevents, the pathological changes of hepatocyte on morphology and interesting micro structure improved and recover, Cortex Moutan Herba Patriniae, Herba Andrographis, Herba Artemisiae Scopariae, mountain mast, Radix Scutellariae, Radix Gentianae, Fructus Forsythiae, Rhizoma Osmundae, Herba Hyperici Japonici, Beishan Mountain Radix Sophorae Tonkinensis have stronger clearing away heat-damp and promoting diuresis with using, the cool fire of detoxifcation, removing heat from blood repercussive effect, modern pharmacology proves that it has share the inhibition hepatitis virus and has duplicated, and liver tissues inflammatory is disappeared, and reduces accumulating of triglyceride.Cortex Magnoliae Officinalis, Rhizoma Cyperi, Matrii Sulfas Exsiccatus, Semen Pruni, Rhizoma Acori Graminei, Herba Eupatorii, Carapax Trionycis, Os Draconis, Concha Ostreae are also with having: the merit of the relieving distension of regulating the flow of vital energy, hard masses softening and resolving, suppressing the hyperactive liver and subsiding YANG, the modern pharmacology proof has: strengthen function immunity, eliminate connective tissue proliferation, the inducing diuresis to remove edema function.

More than all medicines share promptly have the whole dialectical of Traditional Chinese medical theory and the treatment idea; Meet modern pathology again, the understanding of pharmacology.So the present invention is used for the treatment of various acute, chronic hepatitis, liver cirrhosis, cirrhotic ascites and hepatitis gravis, caused: stringy pulse, stream, thin, red tongue, the dry Huang of tongue, hypochondriac pain, anorexia, weak, jaundice, ascites, diseases such as hepatosplenomegaly all have obvious curative effects.

Production technology of the present invention is simple, is applicable to industrial mass manufacture, and therapeutic domain is wide, and curative effect is reliable, and safety has no side effect, and cost is lower.

The present invention can be made into capsule or tablet, powder, every clothes nine grams of being grown up, and every day three times, serious symptom can increase to every clothes 12 grams, every day three times.

Embodiment:

Get Squama Manis 15g, Radix Paeoniae Rubra 15g, Radix Curcumae 15g, Radix Notoginseng 15g, Radix Astragali 20g, Rhizoma Atractylodis Macrocephalae 15g, Radix Paeoniae Alba 15g, Radix Salviae Miltiorrhizae 20g, Carapax Trionycis 20g, Fructus Crataegi 20g, Rhizoma Acori Graminei 15g, Cortex Moutan 15g, Semen Persicae 15g, Fructus Forsythiae 20g, eupolyphage sece steleophaga 15g, Herba Patriniae 20g, Herba Andrographis 20g, Herba Hyperici Japonici 20g, mountain mast 15g, Radix Codonopsis 15g, Herba Artemisiae Scopariae 20g, Radix Angelicae Sinensis 20g, Radix Scutellariae 15g, Cortex Magnoliae Officinalis 15g, Radix Gentianae 15g, Rhizoma Osmundae 15g, Os Draconis 20g, Concha Ostreae 20g, Semen Pruni 10g, Beishan Mountain Radix Sophorae Tonkinensis 15g, with above its powder of 30 five kinds of Chinese medicine is 120 order fine powders, fully mix the zero capsule of packing into, every heavy 1 gram, the position ultraviolet radiation disinfection is adorned in the nontoxic bag and is preserved.

Disease just one: Liu so-and-so, man, 39 years old, peasant, confirmed as hepatitis B virus and carry syndrome through the inspection of First People's Hospital, Shenyang in 98 years, surplus the bimester of hospitalization, characteristic of disease takes a turn for the better and leaves hospital, still adhere to medication treatment after leaving hospital, closely over the past half year, the self-induction poor appetite, weak, right rib pain increases the weight of, and jaundice is obvious, through looking into, " great three positive " reflection occurs, be chronic disease of moving circuitous hepatitis, though take a large amount of patent medicine and injection, interferon, inosine etc. are not all obtained promising result.Take medicine of the present invention mid-April in this year, three times on the one each nine the gram, the bimester after check, two double to " small three positive " continue clothes January, all levying all removed, so far oneself can participate in work, do not see recurrence.

Case two: Lee so-and-so, man, 60 years old, retired worker.Find to suffer from hepatitis B in January, 1999, treated 1 year half, do not see all the time to be clearly better through hospitalization and observation, in in October, 2000 here first visit, levy and see, dim complexion, stringy and thready pulse is puckery, and purplish tongue has ecchymosis, and sees honeybee spider nevus, liver palm, serious yellow cellulitis, private prosecution, right rib twinge does not fixingly move, the time gingival hemorrhage arranged, examination in hospital proves its hepatosplenomegaly, and white/ball ratio is inverted, slight hypersplenism.Analyzing with clinical witness, is the liver cirrhosis commitment that chronic hepatitis causes, through taking medicine of the present invention, March, (every day three times, each ten grams) above all diseases were all removed, and continued the bimester of taking medicine, and through looking into, recovery from illness is with preventing not seeing recurrence.

Claims

1, a kind of medicine for the treatment of hepatopathy, its basic recipe is: Squama Manis 15g, Radix Paeoniae Rubra 15g, Radix Curcumae 15g, Radix Notoginseng 15g, Radix Astragali 20g, Rhizoma Atractylodis Macrocephalae 15g, Radix Paeoniae Alba 15g, Radix Salviae Miltiorrhizae 20g, Carapax Trionycis 20g, Fructus Crataegi 20g, Rhizoma Acori Graminei 15g, Cortex Moutan 15g, Semen Persicae 15g, Fructus Forsythiae 20g, eupolyphage sece steleophaga 15g, Herba Patriniae 20g, Herba Andrographis 20g, Herba Hyperici Japonici 20g, mountain mast 15g, Radix Codonopsis 15g, Herba Artemisiae Scopariae 20g, Radix Angelicae Sinensis 20g, Radix Scutellariae 15g, Cortex Magnoliae Officinalis 15g, Radix Gentianae 15g, Rhizoma Osmundae 15g, Os Draconis 20g, Concha Ostreae 20g, Rhizoma Cyperi 15g, Herba Eupatorii 15g, Rhizoma Dioscoreae 15g, Rhizoma Curcumae 15g, Matrii Sulfas Exsiccatus 10～15g, Semen Pruni 10g, Beishan Mountain Radix Sophorae Tonkinensis 15g.

2, its prescription also can be: Squama Manis 15～10g, also Chinese herbaceous peony 12g, Radix Curcumae 15g, Radix Notoginseng 15～18g, Herba Amaranthi tricoloris stilbene 20g, the Rhizoma Atractylodis Macrocephalae 15～18g, Radix Paeoniae Alba 15g, Radix Salviae Miltiorrhizae 15～25g, Carapax Trionycis 20～30g, Fructus Crataegi 15～20g, Rhizoma Acori Graminei 12g, Cortex Moutan 15g, Semen Persicae 10～15g, Fructus Forsythiae 20g, eupolyphage sece steleophaga 10～15g, Herba Patriniae 15～20g, Herba Andrographis 20～30g, Herba Hyperici Japonici 20～30g, mountain mast 15g, Radix Codonopsis 15g, Herba Artemisiae Scopariae 30g, Radix Angelicae Sinensis 15～20g, Radix Scutellariae 15～18g, Cortex Magnoliae Officinalis 10～15g, Radix Gentianae 15g, Rhizoma Osmundae 15g, Os Draconis 20g, Concha Ostreae 20g, Rhizoma Cyperi 10g, Herba Eupatorii 15g, Rhizoma Dioscoreae 15g, Rhizoma Curcumae 15g, Matrii Sulfas Exsiccatus 10～15g, Semen Pruni 15g, Beishan Mountain Radix Sophorae Tonkinensis 15g.