CN102085332B

CN102085332B - Medicament for treating early ascites due to cirrhosis

Info

Publication number: CN102085332B
Application number: CN2011100098576A
Authority: CN
Inventors: 冯安华
Original assignee: Individual
Current assignee: Individual
Priority date: 2011-01-13
Filing date: 2011-01-13
Publication date: 2012-08-22
Anticipated expiration: 2031-01-13
Also published as: CN102085332A

Abstract

The invention relates to a medicament for treating early ascites due to cirrhosis. Dangshen, radix astragali, stir-fried rhizoma atractylodis macrocephalae, dried orange peel, pericarpium arecae, Chinese yam, poria, rhizoma sparganii, rhizoma zedoariae, immature bitter orange, Mangnolia officinalis, rhubarb, eucommia, Flos Caryophyllata, costus root, radix curcumae, coptis, Baikal skullcap root, phellodendron bark, oriental wormwood, galingale, brown malt, charred hawthorn, charred medicated leaven, trogopterus dung, rhizoma corydalis, licorice root, Plantain seed, desmodium triquetrum and gardenia are decocted and filtered; and the filtrate is extracted to obtain the decoction. The invention effectively displays the compatibility of traditional Chinese medicines, has the advantages of low cost, convenience for treatment, favorable effect, no toxic or side effect and the like, and can realize early detection and treatment, thereby preventing the state of illness from worsening.

Description

A kind of medicine of treating early stage liver cirrhosis ascites

Technical field

The present invention relates to a kind of medicine, particularly relating to a kind of is the medicine of the treatment early stage liver cirrhosis ascites of feedstock production with the Chinese herbal medicine.

Background technology

Liver cirrhosis is that chronic, the progressive diffusivity of the liver due to a variety of causes changes.It is the common end stages eventually of various hepatic injury, is the hepatic fibrosis development that is caused by multiple reason.The early symptom of liver cirrhosis is not obvious, causes the ignorance of patient to the state of an illness easily.Nowadays, liver cirrhosis patient is increasing year by year, and arranging the names in disease death also risen.Liver cirrhosis has become one of representative AD at present.But unclear symptoms shows, and not representing does not have symptom.The early symptom of liver cirrhosis mainly shows clinically to be had: loss of appetite loses weight lassitude and weak; Dim complexion is pitch-dark, diarrhoea, abdominal distention, stomachache, dull pain in liver; Irregular bleeding, the endocrine function imbalance will be striven early discovery, early treatment for early stage liver cirrhosis.When hepatic lesions still is in the fibrosis stage, through active treatment, the state of an illness can reverse or no longer make progress.If disease developed into end-age cirrhosis, some complication such as hepatic encephalopathy (hepatic coma), upper gastrointestinal hemorrhage, ascites, hepatorenal syndrome, infection etc., then prognosis mala often appear in the patient.In a single day liver cirrhosis is early stage to be made a definite diagnosis, should in time carry out the anti-hepatic fibrosis treatment.Prevent cirrhotic ascites, develop into hepatocarcinoma.At present, the treatment of liver cirrhosis is main with Comprehensive Treatment.Liver cirrhosis is main with maintenance in early days, prevents that the state of an illness from further increasing the weight of.

Summary of the invention

The objective of the invention is to bring into play the Chinese medical discrimination medication, provide a kind of cost low, treatment is convenient, and is effective, has no side effect, and early finds early treatment, prevents the thing medicine that the state of an illness increases the weight of.

Medicine of the present invention is to process with following parts of medicines by weight:

Radix Codonopsis 20～30; The Radix Astragali 30～40; Rhizoma Atractylodis Macrocephalae preparata 15～20; Pericarpium Citri Reticulatae 15～20; Pericarpium Arecae 12～18; Rhizoma Dioscoreae 15～20; Poria 15～20; Triangular 12～16; Rhizoma Curcumae 12～16; Fructus Aurantii Immaturus 12～18; Cortex Magnoliae Officinalis 12～16; Radix Et Rhizoma Rhei 9～15; The Cortex Eucommiae 12～15; Flos Caryophylli 15～20; The Radix Aucklandiae 12～15; Radix Curcumae 12～15; Rhizoma Coptidis 12～15; Radix Scutellariae 12～15; Cortex Phellodendri 12～15; Herba Artemisiae Scopariae 20～25; High Rhizoma Alpiniae Officinarum 12～15; Fructus Hordei Germinatus (parched to brown) 20～25; Fructus Crataegi (parched to brown) 20～25; Massa Medicata Fermentata (parched to brown) 20～25; Five Oletum Trogopteroris 12～15; Rhizoma Corydalis 12～15; Radix Glycyrrhizae 6～10; Semen Plantaginis 15～20; Herba Desmodii Triquetri (Herba Tadehagi Triquetri) 20～25; Fructus Gardeniae 20～25.

Above medicine can be made into any dosage form on the pharmaceutics, like decoction, tablet, pill, powder, capsule.

The preferred dosage form of the present invention is a decoction.

The method for preparing of medicine of the present invention: by weight said medicine is used the clear water wash clean, put into the electronics decoction vessel then, add the water of 2 times of amounts; Heat to boiling point, decocted then 20 minutes, extract medicinal liquid; The water that in medicinal residues, adds 2 times of amounts is again heated to boiling point, decocts 20 minutes again, extracts medicinal liquid; Decoct three times continuously, with three mixed decoctions that get of medicinal liquid.

Method for using: every day, each decoction being taken warmly was 1/3rd of three medicinal liquid mixing decoctions once at every turn sooner or later.

In the prescription of the present invention: Radix Codonopsis: invigorating middle warmer, QI invigorating promotes the production of body fluid, and controls weakness of the spleen and stomach, deficiency of both QI and blood, fatigue and lack of strength, lack of appetite, thirsty, chronic diarrhea, proctoptosis; The Radix Astragali: invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.It is weak to be used for the deficiency of vital energy, anorexia and loose stool, and sinking of QI of middle-JIAO, the chronic diarrhea proctoptosis, the metrorrhagia of having blood in stool, the exterior deficiency spontaneous perspiration, deficiency of vital energy edema Radix Astragali disk, carbuncle is difficult bursts, and burst for a long time and do not hold back, the blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst; Chronic nephritis proteinuria, diabetes; Rhizoma Atractylodis Macrocephalae preparata: sweet in the mouth, hardship, warm in nature.Return spleen, stomach warp, invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis; Pericarpium Citri Reticulatae: the merit of appetizing in tool regulating QI and lowering the adverseness, the accent, drying dampness to eliminate phlegm; Pericarpium Arecae: nature and flavor are hot, and tepor is controlled gastral cavity abdomen painful abdominal mass and expanded beriberi, edema; Rhizoma Dioscoreae: heat clearing away, detoxifcation is controlled the epidemic febrile disease heating, toxic-heat and blood stasis, carbuncle and ulcer, toxic swelling, scrofula, anal fistula; Poria: nature and flavor: slightly sweet flavor, property are put down; Gui Jing: GUIXIN, lung, spleen channel; Effect: spleen invigorating, calm the nerves, calm, diuresis, also can promote the health immunocompetence; Triangular: the treating blood disorders blood circulation promoting and blood stasis dispelling, the removing blood stasis circulation of qi promoting, it is depressed to be used for blood stasis, amenorrhea stomachache, diseases such as lump in the abdomen, stomach is rushed down in the removing food stagnancy pain relieving, is used for stagnation of QI due to dyspepsia, abdominal distention; Rhizoma Curcumae: the treating blood disorders blood circulation promoting and blood stasis dispelling, the removing blood stasis circulation of qi promoting, stomach is rushed down in the removing food stagnancy pain relieving, is used for qi depression to blood stasis, amenorrhea stomachache, lump in the abdomen; Eating and drinking without temperance, spleen fortune is not normal, food stagnation distending pain, distension and fullness in the abdomen pain; Fructus Aurantii Immaturus: hardship; Hot; Cold.Return spleen; Stomach; Liver; Heart channel stops in stagnating; The feeling of fullness distending pain; Constipation; Heavy behind the dysentery; Blocked-up chest; Gastroptosis; Uterine prolapse; Proctoptosis; Cortex Magnoliae Officinalis: warming middle-JIAO, the therapeutic method to keep the adverse QI flowing downwards, dampness, expectorant.Control breast abdomen feeling of fullness distending pain, regurgitation, vomiting, dyspepsia does not disappear, and phlegm retention is breathed with cough, the cold-damp dysentery; Radix Et Rhizoma Rhei: heat and toxic materials clearing away, clearing away heat-fire, removing pathogenic heat from blood and toxic substance from the body, eliminating blood stasis and inducing menstruation; The Cortex Eucommiae: invigorating the liver and kidney, bone and muscle strengthening, antiabortive.Control the spinal column ache, foot and knee flaccidity, dribbling urination, uncontrolled urination is itched, and vaginal bleeding during pregnancy is desired to fall, frequent fetal movement, hypertension; Flos Caryophylli: property is hot, the flavor temperature.Go into lung, spleen, stomach, kidney four warps.Effect: warming middle-JIAO, warming the kidney, sending down the abnormal ascending QI.Cure mainly: control singultus, vomiting, regurgitation, dysentery, trusted subordinate's cold type of pain, mass beside the umbilicus, hernia, ringworm; The Radix Aucklandiae: hot, bitter, temperature.Return spleen, stomach, large intestine, three warmers, gallbladder meridian.Promoting the circulation of QI to relieve pain, strengthening the spleen to promote digestion.Be used for breast gastral cavity distending pain, heavy behind the dysentery, food stagnation does not disappear, anorexia.The real intestinal antidiarrheal of Radix Aucklandiae (roasted).Stomachache is used to have loose bowels; Radix Curcumae: hot, bitter, cold.Return liver, the heart, lung meridian.Regulating qi to disperse stagnation, heart fire-clearing upset-relieving, promoting the function of the gallbladder to alleviate jaundice.Be used for the amenorrhea dysmenorrhea, chest and abdomen swelling and pain, twinge, the calentura coma, epilepsy is gone mad, the jaundice dark coloured urine; Rhizoma Coptidis: heat clearing and damp drying, eliminating fire and detoxication.Be used for damp and hot feeling of fullness, vomiting, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, heat in blood is told nosebleed, the conjunctival congestion acid regurgitation, the carbuncle furuncle is quenched one's thirst in toothache; External treatment eczema, eczema, auditory meatus is suppurated; Radix Scutellariae: heat clearing and damp drying, eliminating fire and detoxication, hemostasis, antiabortive; Cortex Phellodendri: heat and toxic materials clearing away medicine; Heat clearing and dampness removing medicine; Herba Artemisiae Scopariae: clearing away heat-damp and promoting diuresis; Jaundice eliminating. cure mainly: jaundice; Dysuria; Eczema pruritus etc. pharmaceutical research has function of gallbladder promoting, and liver function protecting is analgesic, antiinflammatory, blood fat reducing, blood pressure lowering, effects such as coronary dilating; Rhizoma Alpiniae Officinarum: meridian distribution of property and flavor: acrid in the mouth; Bitter; Warm in nature, warming middle-JIAO is regulated the flow of vital energy; Pain relieving, function cures mainly: the cold syndrome of the stomach pain; Dyspepsia; Knee-joint pain; Fructus Hordei Germinatus (parched to brown): the effect of good digestible starch group food is arranged; Fructus Crataegi (parched to brown): be good at treating meat or greasy dyspepsia due to too much; Massa Medicata Fermentata (parched to brown): be beneficial to digestion rice and flour food, Fructus Hordei Germinatus (parched to brown), Fructus Crataegi (parched to brown), Massa Medicata Fermentata (parched to brown) three medicines share, and can strengthen digestive function significantly; Oletum Trogopterori: cure mainly asthenia, cough, asthma, insomnia, dyspepsia etc.Ganoderma has inhibitory action to nervous system, and blood circulation has blood pressure lowering and the effect of strengthening cardiac contractile force, to effects such as respiratory system eliminate the phlegm; Rhizoma Corydalis: warm in nature, acrid in the mouth is bitter, goes into the heart, spleen, liver, lung, invigorates blood circulation promoting the circulation of QI, pain relieving, diuresis; Radix Glycyrrhizae: invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.Be used for weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, the anxious pain of extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong; Semen Plantaginis: clearing away heat and promoting diuresis; Eliminating dampness by diuresis antidiarrheal; Make eye bright; Eliminate the phlegm.Main dysuria; The stranguria with turbid discharge leukorrhagia; The edema distension; The heat-damp in summer dysentery; Conjunctival congestion is hidden from view; The expectorant heat syndrome cough is breathed heavily; Herba Desmodii Triquetri (Herba Tadehagi Triquetri): give birth to do and give birth to heat, hard masses softening and resolving, sharp throat benefiting function, relieving cough and reducing sputum, inducing diuresis and regulating menstruation, hypersexuality; Fructus Gardeniae: pathogenic fire purging relieving restlessness, clearing away heat and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body.Be used for that calentura is vexed, flower subcutaneous ulcer dark coloured urine, blood strangury and dry pain, heat in blood are told nosebleed, the order outstanding person swells and ache, pathogenic fire,toxin and furuncles, sprain.

The present invention treats the medicine of early stage liver cirrhosis ascites, and therapeutic effect is observed 100 examples, effective 95 examples, and effective percentage 95% is cured 60 examples, cure rate 60%.

The present invention effectively brings into play traditional Chinese medical science combination drug, and it is low that the hyperpietic is had a cost, and treatment is convenient, and is effective, has no side effect, and early finds early treatment, advantage such as prevent that the state of an illness from increasing the weight of.

The specific embodiment

Embodiment 1:

Take by weighing raw material by following proportioning:

Radix Codonopsis 20g, Radix Astragali 30g, Rhizoma Atractylodis Macrocephalae preparata 15g, Pericarpium Citri Reticulatae 15g, Pericarpium Arecae 12g, Rhizoma Dioscoreae 15g, Poria 15g, triangular 12g, Rhizoma Curcumae 12g, Fructus Aurantii Immaturus 12g, Cortex Magnoliae Officinalis 12g, Radix Et Rhizoma Rhei 9g, Cortex Eucommiae 12g, Flos Caryophylli 15g, Radix Aucklandiae 12g, Radix Curcumae 12g, Rhizoma Coptidis 12g, Radix Scutellariae 12g, Cortex Phellodendri 12g, Herba Artemisiae Scopariae 20g, Rhizoma Alpiniae Officinarum 12g, Fructus Hordei Germinatus (parched to brown) 20g, Fructus Crataegi (parched to brown) 20g, Massa Medicata Fermentata (parched to brown) 20g, Oletum Trogopterori 12g, Rhizoma Corydalis 12g, Radix Glycyrrhizae 6g, Semen Plantaginis 15g, Herba Desmodii Triquetri (Herba Tadehagi Triquetri) 20g, Fructus Gardeniae 20g.

Concrete method for preparing is:

Said medicine is used the clear water wash clean, puts into the electronics decoction vessel then, adds the water of 2 times of amounts; Heat to boiling point, decocted then 20 minutes, extract medicinal liquid; The water that in medicinal residues, adds 2 times of amounts is again heated to boiling point, decocts 20 minutes again, extracts medicinal liquid; Decoct three times continuously, with three mixed decoctions that get of medicinal liquid.

Embodiment 2:

Take by weighing raw material by following proportioning:

Radix Codonopsis 30g, Radix Astragali 40g, Rhizoma Atractylodis Macrocephalae preparata 20g, Pericarpium Citri Reticulatae 20g, Pericarpium Arecae 18g, Rhizoma Dioscoreae 20g, Poria 20g, triangular 16g, Rhizoma Curcumae 16g, Fructus Aurantii Immaturus 18g, Cortex Magnoliae Officinalis 16g, Radix Et Rhizoma Rhei 15g, Cortex Eucommiae 15g, Flos Caryophylli 20g, Radix Aucklandiae 15g, Radix Curcumae 15g, Rhizoma Coptidis 15g, Radix Scutellariae 15g, Cortex Phellodendri 15g, Herba Artemisiae Scopariae 25g, Rhizoma Alpiniae Officinarum 15g, Fructus Hordei Germinatus (parched to brown) 25g, Fructus Crataegi (parched to brown) 25g, Massa Medicata Fermentata (parched to brown) 25g, Oletum Trogopterori 15g, Rhizoma Corydalis 15g, Radix Glycyrrhizae 10g, Semen Plantaginis 20g, Herba Desmodii Triquetri (Herba Tadehagi Triquetri) 25g, Fructus Gardeniae 25g.

Concrete method for preparing is:

Embodiment 3:

Take by weighing raw material by following proportioning:

Radix Codonopsis 25, the Radix Astragali 35, Rhizoma Atractylodis Macrocephalae preparata 18, Pericarpium Citri Reticulatae 18, Pericarpium Arecae 16, Rhizoma Dioscoreae 18, Poria 18, triangular 15, Rhizoma Curcumae 15, Fructus Aurantii Immaturus 16, Cortex Magnoliae Officinalis 15, Radix Et Rhizoma Rhei 12, the Cortex Eucommiae 14, Flos Caryophylli 18, the Radix Aucklandiae 14, Radix Curcumae 14, Rhizoma Coptidis 14, Radix Scutellariae 14, Cortex Phellodendri 14, Herba Artemisiae Scopariae 24, Rhizoma Alpiniae Officinarum 13, Fructus Hordei Germinatus (parched to brown) 23, Fructus Crataegi (parched to brown) 23, Massa Medicata Fermentata (parched to brown) 23, Oletum Trogopterori 14, Rhizoma Corydalis 14, Radix Glycyrrhizae 8, Semen Plantaginis 18, Herba Desmodii Triquetri (Herba Tadehagi Triquetri) 23, Fructus Gardeniae 23.

Concrete method for preparing is: said medicine is used the clear water wash clean, puts into the electronics decoction vessel then, adds the water of 2 times of amounts; Heat to boiling point, decocted then 20 minutes, extract medicinal liquid; The water that in medicinal residues, adds 2 times of amounts is again heated to boiling point, decocts 20 minutes again, extracts medicinal liquid; Decoct three times continuously, with three mixed decoctions that get of medicinal liquid.

Claims

1. medicine of treating early stage liver cirrhosis ascites is characterized in that being processed by following parts of medicines by weight:

Radix Codonopsis 20～30; The Radix Astragali 30～40; Rhizoma Atractylodis Macrocephalae preparata 15～20; Pericarpium Citri Reticulatae 15～20; Pericarpium Arecae 12～18; Rhizoma Dioscoreae 15～20; Poria 15～20; Triangular 12～16; Rhizoma Curcumae 12～16; Fructus Aurantii Immaturus 12～18; Cortex Magnoliae Officinalis 12～16; Radix Et Rhizoma Rhei 9～15; The Cortex Eucommiae 12～15; Flos Caryophylli 15～20; The Radix Aucklandiae 12～15; Radix Curcumae 12～15; Rhizoma Coptidis 12～15; Radix Scutellariae 12～15; Cortex Phellodendri 12～15; Herba Artemisiae Scopariae 20～25; Rhizoma Alpiniae Officinarum 12～15; Fructus Hordei Germinatus (parched to brown) 20～25; Fructus Crataegi (parched to brown) 20～25; Massa Medicata Fermentata (parched to brown) 20～25; Oletum Trogopterori 12～15; Rhizoma Corydalis 12～15; Radix Glycyrrhizae 6～10; Semen Plantaginis 15～20; Herba Desmodii Triquetri (Herba Tadehagi Triquetri) 20～25; Fructus Gardeniae 20～25.