CN102698192A - Traditional Chinese medicament for treating dilated cardiomyopathy - Google Patents
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Abstract
The invention provides a traditional Chinese medicament for treating dilated cardiomyopathy, which comprises the following components in part by weight: 12 to 18 parts of codonopsis pilosula, 9 to 15 parts of largehead atractylodes rhizome, 9 to 15 parts of poria cocos, 7 to 11 parts of rehmannia glutinosa, 7 to 11 parts of angelica, 7 to 11 parts of radix paeoniae alba, 7 to 11 parts of paeonia veitchii, 7 to 11 parts of ramulus cinnamomi, 4 to 6 parts of astragalus mongholicus, 12 to 18 parts of salvia miltiorrhiza, 7 to 11 parts of turmeric root-tuber, and 7 to 11 parts of radix glycyrrhizae preparata. Compared with the prior art, the traditional Chinese medicament, at the aim of the internal pathogenic factors of the dilated cardiomyopathy, performs treatment on the base of the syndrome differentiation, has a fast effect, is ow in cost, has no toxin and side effects, has an obvious effect and, treats both the symptoms and causes.
Description
Technical field
The present invention relates to a kind of Chinese medicine, more particularly, relate to a kind of Chinese medicine of treating dilated cardiomyopathy.
Background technology
Cardiomyopathy is that a kind of cause of disease is complicated, and basic lesion betides cardiac muscle, causes the heart disease that cardiac muscle can not normal contraction.With cardiac dilatation, tired back is out of breath, orthopnea, and paroxysmal nocturnal dyspnea, edema of lower limbs, or cardiopalmus, uncomfortable in chest, angina pectoris etc. are clinical principal character.All cardiac dilatation are obvious, and heart failure is lasting, or the arrhythmia bigot, and prognosis is not good.Primary disease is divided into two types of primary cardiac myopathy and secondary cardiomyopathys by the cause of disease, is divided into three types of dilated cardiomyopathy, hypertrophic cardiomyopathy and restrictive cardiomyopathys by pathology, and wherein dilated cardiomyopathy comparatively more sees that restrictive cardiomyopathy is domestic rare.The cardiomyopathy onset is slow, but course of disease speed differs.The dilated cardiomyopathy sickness rate is higher, and in the majority with the middle age morbidity, and onset is slower, and it is main mainly showing with uncomfortable in chest, out of breath, edema.This sick complication is more, often with heart failure, hydrothorax, arrhythmia, cardiac sudden death and arterial thrombosis etc.At present still do not have effectively to treat the medicine of dilated cardiomyopathy, adopt cardiac tonic, diuretic, vasodilator to carry out state of an illness control, but this type medicine can cause burden to kidney more.Perhaps can select operation on heart to treat, but surgery cost high, have a big risk.Cardiomyopathy belongs to categories such as the traditional Chinese medical science " cardiopalmus ", " thoracic obstruction ", " the syndrome of dyspnea ", " edema ".
Summary of the invention
The purpose of this invention is to provide a kind of Chinese medicine of treating dilated cardiomyopathy, it is to the inherent pathogenic factor of dilated cardiomyopathy, distinguishes that disease executing control, and with strong points, curative effect is fast, and cost is low, and has no side effect, and can reach to play good prevention effect.
In order to realize above-mentioned purpose, the present invention adopts following technical scheme: a kind of Chinese medicine of treating dilated cardiomyopathy in weight portion, comprises following component: Radix Codonopsis 12-18; Rhizoma Atractylodis Macrocephalae 9-15, Poria 9-15, Radix Rehmanniae Preparata 7-11, Radix Angelicae Sinensis 7-11; Radix Paeoniae Alba 7-11, river Radix Paeoniae Rubra 7-11, Ramulus Cinnamomi 7-11, Radix Astragali 4-6; Radix Salviae Miltiorrhizae 12-18, Radix Curcumae 7-11, Radix Glycyrrhizae Preparata 7-11.
The Analysis on Mechanism of Chinese medicine of the present invention:
Radix Codonopsis: sweet in the mouth; Property is put down.Return spleen; Lung meridian.Invigorating the spleen and replenishing QI, the spleen invigorating lung benefiting.Be used for deficiency of the spleen and lung, the cardiopalmus of breathing hard, anorexia and loose stool, the dyspnea due to deficiency cough, interior-heat is quenched one's thirst." the Chinese crude drug handbook: control the asthenia internal injury, the intestinal cold in the stomach, the sliding chronic dysentery of rushing down, the asthma excessive thirst, the heating spontaneous perspiration, metrorrhagia, tire produce all sick.
The Rhizoma Atractylodis Macrocephalae: bitter in the mouth; Sweet; Warm in nature.Return spleen; The stomach warp.Invigorating the spleen and benefiting QI; The dampness diuretic; Hidroschesis.Be used for deficiency-weakness of spleen-QI; Spiritlessness and weakness." herbal classic is met former ": the Rhizoma Atractylodis Macrocephalae, it is living that the expectorant diuretic is controlled anemofrigid-damp arthralgia with there being the dehumidifying benefit dry, dead flesh convulsion subcutaneous ulcer, the blood between the waist umbilicus that looses, reaching chong channel is disease, the merit of contrary gas pain in the abdomen; Making ripely then has and middle QI invigorating, slakes thirst and help produce saliva, and the hidroschesis heat extraction advances diet, antiabortive effect.
Poria: sweet; Light; Flat.GUIXIN; Spleen; Lung; Kidney channel.Eliminating dampness and diuresis; Invigorating the spleen and regulating the stomach; Mind tranquilizing and the heart calming.Be used for dysuria, the edema distension, the phlegm retention cough with dyspnea, vomiting, insufficiency of the spleen lack of appetite is had loose bowels, palpitation and restlessness, insomnia forgetfulness, seminal emission nebulousurine." herbal classic ": the contrary gas of the main breast side of body, melancholy is angerd frightened heresy and is probably throbbed with fear, and the heart is the knot pain down, cold and heat stuffy sensation with restlessness, cough with dyspnea, mouthful burnt dry tongue, diuresis.
Radix Rehmanniae Preparata: sweet in the mouth; Warm in nature.Return liver; Kidney channel.It is moist to enrich blood; The benefit essence is filled out marrow.It is sallow to be used for the blood tiger; Dizzy cardiopalmus; Menoxenia; Collapse more than; Hepatic and renal YIN deficiency." detailed outline ": fill out bone marrow, longue meat, promoting generation of vital essence and blood, tonifying five ZANG-organs, internal injury deficiency, promoting blood circulation, sharp knowledge, black beard and hair, man's five kinds of strain and seven kinds of impairment, woman's damaging the spleen and stomach threatened abortion, irregular menorrhea, tire produces all kinds of diseases and ailments.
Radix Angelicae Sinensis: sweet in the mouth; Hot; Bitter; Warm in nature.Return liver; The heart; Spleen channel.Enrich blood, invigorate blood circulation, menstruction regulating and pain relieving is moisturized laxation.The all cards of blood deficiency, menoxenia, amenorrhea, dysmenorrhea ， mass in the abdomen knot gathers, metrorrhagia, asthenia cold abdominalgia, flaccidity syndrome and arthralgia syndrome, numbness of the skin, the dryness of the intestine dyschezia, heavy after the bloody dysentery, ulcer sores, injury from falling down.Materia Medica of Decoction: Radix Angelicae Sinensis, few the moon of starting with, with its heart master blood also; It is lunar to go into foot, wraps up in blood also with its spleen; Go into the sufficient the moon of fainting, also with its blood stored in the liver.
The Radix Paeoniae Alba: picric acid, cold.Go into liver, spleen channel.Nourishing blood to suppress the hyperactive liver, slow middle pain relieving, yin fluid astringing is received antiperspirant." herbal classic ": main pathogen stomachache, remove arthralgia due to stagnation of blood, broken hard long-pending, control cold and heat hernia abdominal mass, pain relieving, diuresis, QI invigorating.
River Radix Paeoniae Rubra: hardship is slightly cold.Return Liver Channel.Clearing away heat and cooling blood, eliminating stasis to stop pain.Be used for maculae caused by violent heat pathogen, hematemesis and epistaxis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea, lump in the abdomen stomachache, injury from falling down, carbuncle skin infection." the southern regions of the Yunnan Province book on Chinese herbal medicine ": the purgation of spleen excess fire, sending down the abnormal ascending QI, promoting the circulation of blood, removing blood stasis with potent drugs, the clot that looses ends stomachache, moves back heat in blood, attacks the carbuncle skin ulcer, controls mange.
Ramulus Cinnamomi: hot, sweet, temperature.GUIXIN, lung, urinary bladder channel.The diaphoresis expelling pathogenic factors from muscles, promoting the flow of QI-blood by warming the meridian, supporing yang activating QI, the flat gas that spins.Be used for anemofrigid cold, coldness and pain in the epigastrium, cold in blood amenorrhea, arthralgia." book on Chinese herbal medicine converge with speech ": Ramulus Cinnamomi, dispersing wind and cold by pathogenic factor in the exterior, sends out antiperspirant evil, and cough-relieving is coughed, and the medicine that goes wind pain between podomere is also.Though it is hot that abnormal smells from the patient does not leave, body belongs to branch, only can disperse between the fur flesh natural fibre line of meat parade arm knee joint podomere part.
The Radix Astragali: sweet, tepor.Return lung, spleen, liver, kidney channel.The effect of invigorating QI to consolidate the body surface resistance, hidroschesis detoxification, granulation promoting, diuresis, detumescent.It is weak to be used to treat the deficiency of vital energy, sinking of QI of middle-JIAO, and the chronic diarrhea proctoptosis, the metrorrhagia of having blood in stool, the exterior deficiency spontaneous perspiration, carbuncle is difficult bursts, and burst for a long time and do not hold back, blood deficiency and yellow complexion, interior-heat is quenched one's thirst, chronic nephritis, albuminuria, diabetes etc.
Radix Salviae Miltiorrhizae: bitter in the mouth; Cold nature.GUIXIN; Pericardium; Liver Channel.Blood circulation promoting and blood stasis dispelling; Menstruction regulating and pain relieving; Nourishing blood to tranquillize the mind; The removing heat from blood eliminating carbuncle.Can be used for heat and go into nutrient blood, dysphoria, vexed insomnia, carbuncle pyogenic infections from tumour or sore." herbal classic ": main trusted subordinate's pathogen, borborygmus are faint as leaking water, and cold and heat gather; Broken disease is removed abdominal mass, ends stuffy sensation with restlessness, QI invigorating.
Radix Curcumae: acrid in the mouth; Bitter; Cold in nature.GUIXIN; Liver; Gallbladder meridian.Invigorate blood circulation and end ability; Promoting QI circulation for relieving depression; Removing heat from blood clears away heart-fire; Depressed liver-energy dispersing and function of gallbladder promoting.Be used for all pains of breast abdomen side of body rib, dysmenorrhes, amenorrhea, the lump in the abdomen caking, the calentura coma, demented, infantile convulsion is spitted blood, and nosebleed is equipped with, stranguria with blood, sand Stranguria, jaundice.Tang Materia Medica: main accumulation of blood, the therapeutic method to keep the adverse QI flowing downwards, granulation promoting, hemostasis, broken stagnant blood, stranguria with blood, hematuria, incised wound.
Radix Glycyrrhizae Preparata: sweet, flat.GUIXIN, lung, spleen, stomach warp.The spleen reinforcing stomach function regulating, Yiqi and vein recovery.Be used for weakness of the spleen and stomach, fatigue and weakness, severe palpitation, irregularly intermittent and regularly intermittent pulse can be separated the Radix Aconiti Lateralis Preparata poison.
To the dilated cardiomyopathy due to a little less than the insufficiency of heart-QI, the traditional Chinese medical science is thought heart governing blood and vessels, and deficiency of heart-QI can not agitate blood normally to move, the resistance of the heart arteries and veins stasis of blood, then uncomfortable in chest or pain; The heart is become homeless foster, and then cardiopalmus is out of breath, moving then the aggravation; With the passing of time the deficiency of vital energy involves heart-yang, consumes sad blood, and the blood walking retardation in children is slow, pale complexion then, spiritlessness and weakness; Pale tongue is fat dim red, and tongue is white, thready pulse knot generation, is deficiency of heart-QI, the levying of blood-stasis internal-depression.
The person of choosing in the side, reinforce functional activities of the heart, blood circulation and channel invigorating, Radix Codonopsis invigorating the spleen and replenishing QI; Rhizoma Atractylodis Macrocephalae invigorating the spleen and benefiting QI, the Poria mind tranquilizing and the heart calming, Radix Rehmanniae Preparata is enriched blood moist, and Chinese angelica blood supplementing is invigorated blood circulation; The Radix Paeoniae Alba is nourished blood and seeks, river Radix Paeoniae Rubra sending down the abnormal ascending QI promoting the circulation of blood, Ramulus Cinnamomi promoting the flow of QI-blood by warming the meridian, Radix Astragali invigorating QI to consolidate the body surface resistance; The Radix Salviae Miltiorrhizae blood-promoting and mind-easing, Radix Curcumae blood-activating and qi-promoting, Radix Glycyrrhizae Preparata invigorating the spleen and replenishing QI, coordinating the actions of various ingredients in a prescription.To dilated cardiomyopathy due to a little less than the insufficiency of heart-QI, distinguish that disease executing control, curative effect is fast, and cost is low, determined curative effect, prevention effect is remarkable, doublely takes stopgap measures this.
Form of Chinese drug of the present invention can adopt tablet, granule, pill, capsule, solution, oral liquid, buccal tablet, granule, electuary, powder, suspensoid, powder.Preferably, can adopt solution, granule, pill and capsule.
Result of use
To the Chinese medicine of 50 dilated cardiomyopathy patients (age 35-55) use treatment dilated cardiomyopathy of the present invention, 1 course of treatment of continued treatment (1 month), wherein 17 examples are cured fully, and it is normal that index is recovered; 29 routine remissions; Invalid 4 examples, overall effective percentage reaches 92%, and does not have recurrence.
Instance:
The patient 1: grandson, the women, 39 years old, often uncomfortable in chest, throb with fear out of breath, moving then the aggravation, head-body-pain, pale complexion.Take Chinese medicine of the present invention after 2 weeks, symptom subtracts greatly, the cardiopalmus remission, and disappearance uncomfortable in chest, continued was taken medicine for 2 weeks, and the symptom complete obiteration does not have recurrence so far half a year.
The patient 2: thank certain, and the male, 51 years old, uncomfortable in chest, cardiopalmus, sometimes with tachycardia, spiritlessness and weakness.Pale tongue, tongue is white.After take 2 weeks of Chinese medicine of the present invention, above-mentioned symptom all disappears, and does not see outbreak in 3 months so far.
The patient 3: the minister in ancient times, and the male, 55 years old, often feel general weakness, dizziness uncomfortable in chest is breathed hard after the activity, nervous, arrhythmia.Used Chinese medicine of the present invention to treat afterwards, after half course of treatment, above-mentioned symptom is eased, and sleep improves, and uncomfortable in chest alleviating continues 2 weeks of medication, and above-mentioned symptom all disappears, and does not have recurrence so far.
The specific embodiment
In order to understand the present invention better, through embodiment the present invention is described below.
Embodiment 1
A kind of Chinese medicine of treating dilated cardiomyopathy in weight portion, comprises following component: Radix Codonopsis 12, the Rhizoma Atractylodis Macrocephalae 9, Poria 9, Radix Rehmanniae Preparata 7, Radix Angelicae Sinensis 7, the Radix Paeoniae Alba 7, river Radix Paeoniae Rubra 7, Ramulus Cinnamomi 7, the Radix Astragali 4, Radix Salviae Miltiorrhizae 12, Radix Curcumae 7, Radix Glycyrrhizae Preparata 7.
Its preparation method is:
In weight portion, get Radix Codonopsis 12, the Rhizoma Atractylodis Macrocephalae 9, Poria 9, Radix Rehmanniae Preparata 7, Radix Angelicae Sinensis 7, the Radix Paeoniae Alba 7, river Radix Paeoniae Rubra 7, Ramulus Cinnamomi 7, the Radix Astragali 4, Radix Salviae Miltiorrhizae 12, Radix Curcumae 7, Radix Glycyrrhizae Preparata 7; Above-mentioned Chinese medicine is cleaned, and decontamination is put into container and is added water and do not have medical material to soak, and after 30 minutes, big fire decocts to boiling, and slow fire was endured 1 hour slowly then; Medicine juice is leached, bag distribution packaging, one bag of 200ml sooner or later respectively obeys one bag.
Embodiment 2
A kind of Chinese medicine of treating dilated cardiomyopathy in weight portion, comprises following component: Radix Codonopsis 18, the Rhizoma Atractylodis Macrocephalae 15, Poria 15, Radix Rehmanniae Preparata 11, Radix Angelicae Sinensis 11, the Radix Paeoniae Alba 11, river Radix Paeoniae Rubra 11, Ramulus Cinnamomi 11, the Radix Astragali 6, Radix Salviae Miltiorrhizae 18, Radix Curcumae 11, Radix Glycyrrhizae Preparata 11.
Its preparation method is:
In weight portion, get Radix Codonopsis 18, the Rhizoma Atractylodis Macrocephalae 15, Poria 15, Radix Rehmanniae Preparata 11, Radix Angelicae Sinensis 11, the Radix Paeoniae Alba 11, river Radix Paeoniae Rubra 11, Ramulus Cinnamomi 11, the Radix Astragali 6, Radix Salviae Miltiorrhizae 18, Radix Curcumae 11, Radix Glycyrrhizae Preparata 11; Cleaning, drying mix above-mentioned medical material, and per kilogram adds about 10L water, and 0.5-1 at a simmer hour, big fire was fried in shallow oil 1-2 hour; Get decocting liquid and cross 150 mesh sieves, the back is concentrated into the clear paste of relative density 1.10-1.20 with concentrator, gets 2/3 clear paste 120 ℃ of following spray dryinges, the clear paste powder, powder is mixed granulation with residue 1/3 clear paste; The packing of granule racking machine promptly gets granule.
Embodiment 3
A kind of Chinese medicine of treating dilated cardiomyopathy in weight portion, comprises following component: Radix Codonopsis 15, the Rhizoma Atractylodis Macrocephalae 12, Poria 12, Radix Rehmanniae Preparata 9, Radix Angelicae Sinensis 9, the Radix Paeoniae Alba 9, river Radix Paeoniae Rubra 9, Ramulus Cinnamomi 9, the Radix Astragali 5, Radix Salviae Miltiorrhizae 15, Radix Curcumae 9, Radix Glycyrrhizae Preparata 9.
Its preparation method is:
In weight portion, get Radix Codonopsis 15, the Rhizoma Atractylodis Macrocephalae 12, Poria 12, Radix Rehmanniae Preparata 9, Radix Angelicae Sinensis 9, the Radix Paeoniae Alba 9, river Radix Paeoniae Rubra 9, Ramulus Cinnamomi 9, the Radix Astragali 5, Radix Salviae Miltiorrhizae 15, Radix Curcumae 9, Radix Glycyrrhizae Preparata 9; Cleaning, drying mix above-mentioned medical material, use pulverizer to pulverize and are 150-180 order fine powder, and add suitable Mel and mix, the pellet processing machine pill, cold drying, packing promptly gets pill.
Embodiment 4
A kind of Chinese medicine of treating dilated cardiomyopathy in weight portion, comprises following component: Radix Codonopsis 15, the Rhizoma Atractylodis Macrocephalae 12, Poria 12, Radix Rehmanniae Preparata 9, Radix Angelicae Sinensis 9, the Radix Paeoniae Alba 9, river Radix Paeoniae Rubra 9, Ramulus Cinnamomi 9, the Radix Astragali 5, Radix Salviae Miltiorrhizae 15, Radix Curcumae 9, Radix Glycyrrhizae Preparata 9.
Its preparation method is:
In weight portion, get Radix Codonopsis 15, the Rhizoma Atractylodis Macrocephalae 12, Poria 12, Radix Rehmanniae Preparata 9, Radix Angelicae Sinensis 9, the Radix Paeoniae Alba 9, river Radix Paeoniae Rubra 9, Ramulus Cinnamomi 9, the Radix Astragali 5, Radix Salviae Miltiorrhizae 15, Radix Curcumae 9, Radix Glycyrrhizae Preparata 9; Cleaning, drying mix above-mentioned medical material, and per kilogram adds about 10L water, and 0.5-1 at a simmer hour, big fire was fried in shallow oil 1-2 hour; Get decocting liquid and cross 150 mesh sieves, the back is concentrated into the clear paste of relative density 1.10-1.20 with concentrator, gets 2/3 clear paste 120 ℃ of following spray dryinges, the clear paste powder, powder is mixed granulation with residue 1/3 clear paste; Granule is processed the 0.4g/ capsules with the capsule filler.
Claims (4)
1. a Chinese medicine of treating dilated cardiomyopathy is characterized in that, in weight portion, comprises following component: Radix Codonopsis 12-18, Rhizoma Atractylodis Macrocephalae 9-15; Poria 9-15, Radix Rehmanniae Preparata 7-11, Radix Angelicae Sinensis 7-11, Radix Paeoniae Alba 7-11, river Radix Paeoniae Rubra 7-11; Ramulus Cinnamomi 7-11, Radix Astragali 4-6, Radix Salviae Miltiorrhizae 12-18, Radix Curcumae 7-11, Radix Glycyrrhizae Preparata 7-11.
2. Chinese medicine according to claim 1 is characterized in that, in weight portion, preferably comprises following component: Radix Codonopsis 15, the Rhizoma Atractylodis Macrocephalae 12, Poria 12, Radix Rehmanniae Preparata 9, Radix Angelicae Sinensis 9, the Radix Paeoniae Alba 9, river Radix Paeoniae Rubra 9, Ramulus Cinnamomi 9, the Radix Astragali 5, Radix Salviae Miltiorrhizae 15, Radix Curcumae 9, Radix Glycyrrhizae Preparata 9.
3. Chinese medicine according to claim 1 is characterized in that, said Chinese medicine adopts tablet, granule, pill, capsule, solution, oral liquid, buccal tablet, granule, electuary, powder, suspensoid, powder.
4. Chinese medicine according to claim 1 is characterized in that said Chinese medicine preferably adopts solution, granule, pill and capsule.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103263594A (en) * | 2013-04-29 | 2013-08-28 | 翁炳焕 | Traditional Chinese medicine composition for treating dilated cardiomyopathy |
| CN104984037A (en) * | 2015-07-27 | 2015-10-21 | 青岛云天生物技术有限公司 | Traditional Chinese medicine preparation for treatment of dilated cardiomyopathy and preparing method thereof |
-
2012
- 2012-05-29 CN CN2012101701423A patent/CN102698192A/en not_active Withdrawn
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103263594A (en) * | 2013-04-29 | 2013-08-28 | 翁炳焕 | Traditional Chinese medicine composition for treating dilated cardiomyopathy |
| CN104984037A (en) * | 2015-07-27 | 2015-10-21 | 青岛云天生物技术有限公司 | Traditional Chinese medicine preparation for treatment of dilated cardiomyopathy and preparing method thereof |
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Address after: Jinjiang District Jinhua Road Chengdu City, Sichuan province 610000 section of No. 8 Building 1 (Wanda Plaza) 11 Unit No. 2301 Applicant after: Chengdu Lyudi Technology Co., Ltd. Address before: 610000 Jinjiang District, Chengdu, East Street, 18-32 No. 1, floor 5, layer 517, Applicant before: Chengdu Lyudi Technology Co., Ltd. |
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Application publication date: 20121003 |