CN1407893A - 治疗寄生原虫感染所致疾病的三嗪酮类化合物 - Google Patents

治疗寄生原虫感染所致疾病的三嗪酮类化合物 Download PDF

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Publication number
CN1407893A
CN1407893A CN00816674A CN00816674A CN1407893A CN 1407893 A CN1407893 A CN 1407893A CN 00816674 A CN00816674 A CN 00816674A CN 00816674 A CN00816674 A CN 00816674A CN 1407893 A CN1407893 A CN 1407893A
Authority
CN
China
Prior art keywords
toltrazuril
cell
neospora
compounds
animal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN00816674A
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English (en)
Chinese (zh)
Inventor
G·格雷夫
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of CN1407893A publication Critical patent/CN1407893A/zh
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
    • A01N43/66—1,3,5-Triazines, not hydrogenated and not substituted at the ring nitrogen atoms
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
    • A01N43/707—1,2,3- or 1,2,4-triazines; Hydrogenated 1,2,3- or 1,2,4-triazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dentistry (AREA)
  • Agronomy & Crop Science (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Neurology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CN00816674A 1999-12-03 2000-11-21 治疗寄生原虫感染所致疾病的三嗪酮类化合物 Pending CN1407893A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19958388A DE19958388A1 (de) 1999-12-03 1999-12-03 Triazinonverbindungen zur Behandlung von durch den Befall mit parasitischen Protozoen bedingten Krankheiten
DE19958388.9 1999-12-03

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN200910142693A Division CN101632676A (zh) 1999-12-03 2000-11-21 治疗寄生原虫感染所致疾病的三嗪酮类化合物

Publications (1)

Publication Number Publication Date
CN1407893A true CN1407893A (zh) 2003-04-02

Family

ID=7931344

Family Applications (2)

Application Number Title Priority Date Filing Date
CN00816674A Pending CN1407893A (zh) 1999-12-03 2000-11-21 治疗寄生原虫感染所致疾病的三嗪酮类化合物
CN200910142693A Pending CN101632676A (zh) 1999-12-03 2000-11-21 治疗寄生原虫感染所致疾病的三嗪酮类化合物

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN200910142693A Pending CN101632676A (zh) 1999-12-03 2000-11-21 治疗寄生原虫感染所致疾病的三嗪酮类化合物

Country Status (16)

Country Link
US (1) US9399037B2 (ja)
EP (1) EP1246624B1 (ja)
JP (1) JP5031163B2 (ja)
CN (2) CN1407893A (ja)
AT (1) ATE298573T1 (ja)
AU (1) AU783437B2 (ja)
BR (1) BR0015996A (ja)
CA (1) CA2394188C (ja)
DE (2) DE19958388A1 (ja)
DK (1) DK1246624T3 (ja)
ES (1) ES2243323T3 (ja)
HU (1) HU226379B1 (ja)
MX (1) MXPA02005479A (ja)
NZ (1) NZ519327A (ja)
WO (1) WO2001039778A2 (ja)
ZA (1) ZA200203476B (ja)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102007025908A1 (de) 2007-06-01 2008-12-04 Bayer Healthcare Ag Formulierungen enthaltend Triazinone und Eisen
MX2008009818A (es) 2008-07-31 2010-02-01 Avi Mex S A De C V Lab Combinacion coccidicida para uso veterinario.
DE102009012423A1 (de) 2009-03-10 2010-09-16 Bayer Animal Health Gmbh Zubereitung auf Ölbasis
DE102009038949A1 (de) * 2009-08-26 2011-03-03 Bayer Animal Health Gmbh Neue Verwendung von heterocyclisch substituierten 1,2,4-Triazindionen
JP7350759B2 (ja) 2018-02-26 2023-09-26 アルゼキュア ファーマ アーべー ニューロトロフィンに関連する疾患を治療するためのトリアジン誘導体
GB201810668D0 (en) 2018-06-28 2018-08-15 Stiftelsen Alzecure New compounds

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4631278A (en) * 1984-08-01 1986-12-23 Janssen Pharmaceutica N.V. Anti-protozoal α-aryl-4-(4,5-dihydro-3,5-dioxo-1,2,4-triazin-2(3H)-yl)-benzeneacetonitrile derivatives, pharmaceutical compositions, and method of use therefor
US4778887A (en) * 1984-08-01 1988-10-18 Janssen Pharmaceutica N.V. α-aryl-4-(4,5-dihydro-3,5-dioxo-1,2,4-triazin-2(3H)-yl)-benzeneacetonitriles
DE3805660A1 (de) * 1988-02-24 1989-09-07 Bayer Ag Substituierte 1,2,4-triazindione, verfahren zu ihrer herstellung und ihre verwendung
DE3826058A1 (de) * 1988-07-30 1990-02-08 Bayer Ag Mittel gegen fischparasiten
US5196562A (en) * 1988-10-08 1993-03-23 Bayer Aktiengesellschaft Substituted 1,3,5-triazinetriones, for use against parasitic protozoa
US4933341A (en) * 1988-10-08 1990-06-12 Bayer Aktiengesellschaft Substituted 1,3,5-triazinetriones, for use against parasitic protozoa
EP0377903A3 (de) * 1989-01-09 1991-07-17 Bayer Ag Substituierte Hexahydro-1,2,4-triazindione, Verfahren zu ihrer Herstellung, Zwischenprodukte dafür und ihre Verwendung
CN1044905A (zh) * 1989-02-16 1990-08-29 赫彻斯特股份公司 鱼和昆虫寄生虫对抗剂
DE4030042A1 (de) * 1990-05-17 1991-11-21 Bayer Ag Verwendung von substituierten 1,2,4-triazindionen
US5256632A (en) * 1990-05-30 1993-10-26 Bayer Aktiengesellschaft Herbicidal sulphonylated carboxamides
DE19519821A1 (de) * 1995-05-31 1996-12-05 Bayer Ag Mittel gegen parasitäre Protozoen
ATE271122T1 (de) * 1996-11-12 2004-07-15 Pfizer Attenuierter lebender neospora impfstoff
US5883095A (en) * 1997-08-07 1999-03-16 University Of Kentucky Research Foundation Formulations and methods to treat and prevent equine protozoal myeloencephalitis
WO1998043644A1 (en) * 1997-03-31 1998-10-08 David Granstrom Formulations and methods to treat and prevent equine protozoal myeloencephalitis
US5830893A (en) * 1997-04-23 1998-11-03 Mortar & Pestle Veterinary Pharmacy, Inc. Treatment of equine protozoan myeloencephalitis using triazinediones
ATE352315T1 (de) * 1997-10-20 2007-02-15 Bayer Corp Neospora impstoff
US6248329B1 (en) * 1998-06-01 2001-06-19 Ramaswamy Chandrashekar Parasitic helminth cuticlin nucleic acid molecules and uses thereof
BR9914385A (pt) * 1998-10-08 2001-07-17 New Ace Res Company Composição útil para o tratamento e prevenção de infecções protozoárias no homem e em animais, e, método de tratamento de uma infecção protozoária no homem e em animais
KR20010080571A (ko) * 1998-12-22 2001-08-22 조지 제이. 리코스 사르코시스티스, 네오스포라 및 톡소플라즈마에 의한 질병치료용 트리아진온 화합물
US6150361A (en) * 1998-12-22 2000-11-21 Bayer Corporation Triazineone compounds for treating diseases due to sarcosystis, neospora and toxoplasma
US6194408B1 (en) * 1998-12-22 2001-02-27 Bayer Corporation Triazineone compounds for treating diseases due to Sarcocystis, Neospora and Toxoplasma

Also Published As

Publication number Publication date
CA2394188C (en) 2010-01-26
ES2243323T3 (es) 2005-12-01
HUP0203534A3 (en) 2003-10-28
HUP0203534A2 (hu) 2003-01-28
DE50010648D1 (de) 2005-08-04
ZA200203476B (en) 2003-05-02
WO2001039778A3 (de) 2002-01-31
EP1246624A2 (de) 2002-10-09
EP1246624B1 (de) 2005-06-29
CN101632676A (zh) 2010-01-27
US9399037B2 (en) 2016-07-26
HU226379B1 (en) 2008-10-28
WO2001039778A2 (de) 2001-06-07
DK1246624T3 (da) 2005-10-03
AU783437B2 (en) 2005-10-27
DE19958388A1 (de) 2001-06-07
CA2394188A1 (en) 2001-06-07
JP5031163B2 (ja) 2012-09-19
BR0015996A (pt) 2002-08-06
AU1524401A (en) 2001-06-12
US20090181040A1 (en) 2009-07-16
NZ519327A (en) 2004-10-29
JP2003515563A (ja) 2003-05-07
MXPA02005479A (es) 2003-01-28
ATE298573T1 (de) 2005-07-15

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