CN1407893A - 治疗寄生原虫感染所致疾病的三嗪酮类化合物 - Google Patents

治疗寄生原虫感染所致疾病的三嗪酮类化合物 Download PDF

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Publication number
CN1407893A
CN1407893A CN00816674A CN00816674A CN1407893A CN 1407893 A CN1407893 A CN 1407893A CN 00816674 A CN00816674 A CN 00816674A CN 00816674 A CN00816674 A CN 00816674A CN 1407893 A CN1407893 A CN 1407893A
Authority
CN
China
Prior art keywords
toltrazuril
cell
neospora
compounds
animal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN00816674A
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English (en)
Chinese (zh)
Inventor
G·格雷夫
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of CN1407893A publication Critical patent/CN1407893A/zh
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
    • A01N43/66—1,3,5-Triazines, not hydrogenated and not substituted at the ring nitrogen atoms
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
    • A01N43/707—1,2,3- or 1,2,4-triazines; Hydrogenated 1,2,3- or 1,2,4-triazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CN00816674A 1999-12-03 2000-11-21 治疗寄生原虫感染所致疾病的三嗪酮类化合物 Pending CN1407893A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19958388.9 1999-12-03
DE19958388A DE19958388A1 (de) 1999-12-03 1999-12-03 Triazinonverbindungen zur Behandlung von durch den Befall mit parasitischen Protozoen bedingten Krankheiten

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN200910142693A Division CN101632676A (zh) 1999-12-03 2000-11-21 治疗寄生原虫感染所致疾病的三嗪酮类化合物

Publications (1)

Publication Number Publication Date
CN1407893A true CN1407893A (zh) 2003-04-02

Family

ID=7931344

Family Applications (2)

Application Number Title Priority Date Filing Date
CN00816674A Pending CN1407893A (zh) 1999-12-03 2000-11-21 治疗寄生原虫感染所致疾病的三嗪酮类化合物
CN200910142693A Pending CN101632676A (zh) 1999-12-03 2000-11-21 治疗寄生原虫感染所致疾病的三嗪酮类化合物

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN200910142693A Pending CN101632676A (zh) 1999-12-03 2000-11-21 治疗寄生原虫感染所致疾病的三嗪酮类化合物

Country Status (16)

Country Link
US (1) US9399037B2 (ja)
EP (1) EP1246624B1 (ja)
JP (1) JP5031163B2 (ja)
CN (2) CN1407893A (ja)
AT (1) ATE298573T1 (ja)
AU (1) AU783437B2 (ja)
BR (1) BR0015996A (ja)
CA (1) CA2394188C (ja)
DE (2) DE19958388A1 (ja)
DK (1) DK1246624T3 (ja)
ES (1) ES2243323T3 (ja)
HU (1) HU226379B1 (ja)
MX (1) MXPA02005479A (ja)
NZ (1) NZ519327A (ja)
WO (1) WO2001039778A2 (ja)
ZA (1) ZA200203476B (ja)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102007025908A1 (de) 2007-06-01 2008-12-04 Bayer Healthcare Ag Formulierungen enthaltend Triazinone und Eisen
MX2008009818A (es) 2008-07-31 2010-02-01 Avi Mex S A De C V Lab Combinacion coccidicida para uso veterinario.
DE102009012423A1 (de) 2009-03-10 2010-09-16 Bayer Animal Health Gmbh Zubereitung auf Ölbasis
DE102009038949A1 (de) * 2009-08-26 2011-03-03 Bayer Animal Health Gmbh Neue Verwendung von heterocyclisch substituierten 1,2,4-Triazindionen
SG11202007136VA (en) 2018-02-26 2020-08-28 AlzeCure Pharma AB Triazine derivatives for treating diseases relating to neurotrophins
GB201810668D0 (en) 2018-06-28 2018-08-15 Stiftelsen Alzecure New compounds

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4778887A (en) 1984-08-01 1988-10-18 Janssen Pharmaceutica N.V. α-aryl-4-(4,5-dihydro-3,5-dioxo-1,2,4-triazin-2(3H)-yl)-benzeneacetonitriles
US4631278A (en) 1984-08-01 1986-12-23 Janssen Pharmaceutica N.V. Anti-protozoal α-aryl-4-(4,5-dihydro-3,5-dioxo-1,2,4-triazin-2(3H)-yl)-benzeneacetonitrile derivatives, pharmaceutical compositions, and method of use therefor
DE3805660A1 (de) 1988-02-24 1989-09-07 Bayer Ag Substituierte 1,2,4-triazindione, verfahren zu ihrer herstellung und ihre verwendung
DE3826058A1 (de) 1988-07-30 1990-02-08 Bayer Ag Mittel gegen fischparasiten
US4933341A (en) 1988-10-08 1990-06-12 Bayer Aktiengesellschaft Substituted 1,3,5-triazinetriones, for use against parasitic protozoa
US5196562A (en) 1988-10-08 1993-03-23 Bayer Aktiengesellschaft Substituted 1,3,5-triazinetriones, for use against parasitic protozoa
EP0377903A3 (de) 1989-01-09 1991-07-17 Bayer Ag Substituierte Hexahydro-1,2,4-triazindione, Verfahren zu ihrer Herstellung, Zwischenprodukte dafür und ihre Verwendung
CN1044905A (zh) 1989-02-16 1990-08-29 赫彻斯特股份公司 鱼和昆虫寄生虫对抗剂
DE4030042A1 (de) 1990-05-17 1991-11-21 Bayer Ag Verwendung von substituierten 1,2,4-triazindionen
US5256632A (en) 1990-05-30 1993-10-26 Bayer Aktiengesellschaft Herbicidal sulphonylated carboxamides
DE19519821A1 (de) * 1995-05-31 1996-12-05 Bayer Ag Mittel gegen parasitäre Protozoen
DE69729839T2 (de) 1996-11-12 2005-07-21 Pfizer Inc. Attenuierter lebender Neospora Impfstoff
BR9808114A (pt) * 1997-03-31 2000-03-08 David Granstrom Formulação de ração para cavalos utilizável para tratar epm, processos para tratar pm em um cavalo que necessita deste tratamento, para prevenir infecção com s. neutrona em cavalos, e, para exterminar s. neurona em cavalos
US5883095A (en) * 1997-08-07 1999-03-16 University Of Kentucky Research Foundation Formulations and methods to treat and prevent equine protozoal myeloencephalitis
US5830893A (en) * 1997-04-23 1998-11-03 Mortar & Pestle Veterinary Pharmacy, Inc. Treatment of equine protozoan myeloencephalitis using triazinediones
AU745183B2 (en) * 1997-10-20 2002-03-14 Bayer Corporation Neospora vaccines
US6248329B1 (en) 1998-06-01 2001-06-19 Ramaswamy Chandrashekar Parasitic helminth cuticlin nucleic acid molecules and uses thereof
NZ510998A (en) * 1998-10-08 2003-02-28 New Ace Res Company Triazine based anitcoccidial agents for treating protozoal infections
US6150361A (en) * 1998-12-22 2000-11-21 Bayer Corporation Triazineone compounds for treating diseases due to sarcosystis, neospora and toxoplasma
WO2000037084A1 (en) * 1998-12-22 2000-06-29 Bayer Corporation Triazineone compounds for treating diseases due to sarcosystis, neospora and toxoplasma
US6194408B1 (en) * 1998-12-22 2001-02-27 Bayer Corporation Triazineone compounds for treating diseases due to Sarcocystis, Neospora and Toxoplasma

Also Published As

Publication number Publication date
DK1246624T3 (da) 2005-10-03
CA2394188C (en) 2010-01-26
HUP0203534A3 (en) 2003-10-28
EP1246624B1 (de) 2005-06-29
HUP0203534A2 (hu) 2003-01-28
JP5031163B2 (ja) 2012-09-19
US9399037B2 (en) 2016-07-26
WO2001039778A2 (de) 2001-06-07
EP1246624A2 (de) 2002-10-09
DE19958388A1 (de) 2001-06-07
AU1524401A (en) 2001-06-12
HU226379B1 (en) 2008-10-28
CN101632676A (zh) 2010-01-27
DE50010648D1 (de) 2005-08-04
JP2003515563A (ja) 2003-05-07
ES2243323T3 (es) 2005-12-01
WO2001039778A3 (de) 2002-01-31
ZA200203476B (en) 2003-05-02
MXPA02005479A (es) 2003-01-28
NZ519327A (en) 2004-10-29
BR0015996A (pt) 2002-08-06
ATE298573T1 (de) 2005-07-15
CA2394188A1 (en) 2001-06-07
US20090181040A1 (en) 2009-07-16
AU783437B2 (en) 2005-10-27

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