DE19958388A1 - Triazinonverbindungen zur Behandlung von durch den Befall mit parasitischen Protozoen bedingten Krankheiten - Google Patents

Triazinonverbindungen zur Behandlung von durch den Befall mit parasitischen Protozoen bedingten Krankheiten

Info

Publication number
DE19958388A1
DE19958388A1 DE19958388A DE19958388A DE19958388A1 DE 19958388 A1 DE19958388 A1 DE 19958388A1 DE 19958388 A DE19958388 A DE 19958388A DE 19958388 A DE19958388 A DE 19958388A DE 19958388 A1 DE19958388 A1 DE 19958388A1
Authority
DE
Germany
Prior art keywords
treatment
cells
compounds
caninum
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19958388A
Other languages
German (de)
English (en)
Inventor
Gisela Greif
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Priority to DE19958388A priority Critical patent/DE19958388A1/de
Priority to CN00816674A priority patent/CN1407893A/zh
Priority to HU0203534A priority patent/HU226379B1/hu
Priority to AT00977586T priority patent/ATE298573T1/de
Priority to BR0015996-4A priority patent/BR0015996A/pt
Priority to EP00977586A priority patent/EP1246624B1/de
Priority to PCT/EP2000/011837 priority patent/WO2001039778A2/de
Priority to ES00977586T priority patent/ES2243323T3/es
Priority to MXPA02005479A priority patent/MXPA02005479A/es
Priority to NZ519327A priority patent/NZ519327A/en
Priority to CN200910142693A priority patent/CN101632676A/zh
Priority to AU15244/01A priority patent/AU783437B2/en
Priority to DK00977586T priority patent/DK1246624T3/da
Priority to DE50010648T priority patent/DE50010648D1/de
Priority to JP2001541510A priority patent/JP5031163B2/ja
Priority to CA2394188A priority patent/CA2394188C/en
Publication of DE19958388A1 publication Critical patent/DE19958388A1/de
Priority to ZA200203476A priority patent/ZA200203476B/en
Priority to US11/871,302 priority patent/US9399037B2/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
    • A01N43/66—1,3,5-Triazines, not hydrogenated and not substituted at the ring nitrogen atoms
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
    • A01N43/707—1,2,3- or 1,2,4-triazines; Hydrogenated 1,2,3- or 1,2,4-triazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dentistry (AREA)
  • Agronomy & Crop Science (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Neurology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE19958388A 1999-12-03 1999-12-03 Triazinonverbindungen zur Behandlung von durch den Befall mit parasitischen Protozoen bedingten Krankheiten Withdrawn DE19958388A1 (de)

Priority Applications (18)

Application Number Priority Date Filing Date Title
DE19958388A DE19958388A1 (de) 1999-12-03 1999-12-03 Triazinonverbindungen zur Behandlung von durch den Befall mit parasitischen Protozoen bedingten Krankheiten
NZ519327A NZ519327A (en) 1999-12-03 2000-11-21 Triazinone compounds for treating diseases resulting from infestation with parasitic protozoans
CN200910142693A CN101632676A (zh) 1999-12-03 2000-11-21 治疗寄生原虫感染所致疾病的三嗪酮类化合物
AT00977586T ATE298573T1 (de) 1999-12-03 2000-11-21 Triazinonverbindungen zur behandlung von durch den befall mit parasitischen protozoen bedingten krankheiten
BR0015996-4A BR0015996A (pt) 1999-12-03 2000-11-21 Compostos de triazinona para o tratamento de doenças causadas pela infestação de protozoários parasìticos
EP00977586A EP1246624B1 (de) 1999-12-03 2000-11-21 Triazinonverbindungen zur behandlung von durch den befall mit parasitischen protozoen bedingten krankheiten
PCT/EP2000/011837 WO2001039778A2 (de) 1999-12-03 2000-11-21 Triazinonverbindungen zur behandlung von durch den befall mit parasitischen protozoen bedingten krankheiten
ES00977586T ES2243323T3 (es) 1999-12-03 2000-11-21 Compuestos de triazinona para el tratamiento de enfermedades debidas al ataque por protozoos parasitarios.
MXPA02005479A MXPA02005479A (es) 1999-12-03 2000-11-21 Compuestos de triazinona para el tratamiento de enfermedades resultantes de ataque por protozoos parasitantes.
CN00816674A CN1407893A (zh) 1999-12-03 2000-11-21 治疗寄生原虫感染所致疾病的三嗪酮类化合物
HU0203534A HU226379B1 (en) 1999-12-03 2000-11-21 Use of triazinone derivatives for the preparation of compositions treating diseases resulting from infestation with parasitic protozoans
AU15244/01A AU783437B2 (en) 1999-12-03 2000-11-21 Triazinone compounds for treating diseases resulting from infestation with parasitic protozoans
DK00977586T DK1246624T3 (da) 1999-12-03 2000-11-21 Triazinonforbindelser til behandling af sygdomme, der skyldes angreb med parasitiske protozoer
DE50010648T DE50010648D1 (de) 1999-12-03 2000-11-21 Triazinonverbindungen zur behandlung von durch den befall mit parasitischen protozoen bedingten krankheiten
JP2001541510A JP5031163B2 (ja) 1999-12-03 2000-11-21 寄生性原虫類の蔓延から生ずる疾患の処置のためのトリアジノン化合物
CA2394188A CA2394188C (en) 1999-12-03 2000-11-21 Triazinone compounds for treating diseases resulting from infestation with parasitic protozoans
ZA200203476A ZA200203476B (en) 1999-12-03 2002-05-02 Triazinone compounds for treating diseases resulting from infestation with parasitic protozoans.
US11/871,302 US9399037B2 (en) 1999-12-03 2007-10-12 Triazinone compounds for treating diseases resulting from infestation with parasitic protozoans

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19958388A DE19958388A1 (de) 1999-12-03 1999-12-03 Triazinonverbindungen zur Behandlung von durch den Befall mit parasitischen Protozoen bedingten Krankheiten

Publications (1)

Publication Number Publication Date
DE19958388A1 true DE19958388A1 (de) 2001-06-07

Family

ID=7931344

Family Applications (2)

Application Number Title Priority Date Filing Date
DE19958388A Withdrawn DE19958388A1 (de) 1999-12-03 1999-12-03 Triazinonverbindungen zur Behandlung von durch den Befall mit parasitischen Protozoen bedingten Krankheiten
DE50010648T Expired - Lifetime DE50010648D1 (de) 1999-12-03 2000-11-21 Triazinonverbindungen zur behandlung von durch den befall mit parasitischen protozoen bedingten krankheiten

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE50010648T Expired - Lifetime DE50010648D1 (de) 1999-12-03 2000-11-21 Triazinonverbindungen zur behandlung von durch den befall mit parasitischen protozoen bedingten krankheiten

Country Status (16)

Country Link
US (1) US9399037B2 (ja)
EP (1) EP1246624B1 (ja)
JP (1) JP5031163B2 (ja)
CN (2) CN1407893A (ja)
AT (1) ATE298573T1 (ja)
AU (1) AU783437B2 (ja)
BR (1) BR0015996A (ja)
CA (1) CA2394188C (ja)
DE (2) DE19958388A1 (ja)
DK (1) DK1246624T3 (ja)
ES (1) ES2243323T3 (ja)
HU (1) HU226379B1 (ja)
MX (1) MXPA02005479A (ja)
NZ (1) NZ519327A (ja)
WO (1) WO2001039778A2 (ja)
ZA (1) ZA200203476B (ja)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102007025908A1 (de) 2007-06-01 2008-12-04 Bayer Healthcare Ag Formulierungen enthaltend Triazinone und Eisen
US11352332B2 (en) 2018-02-26 2022-06-07 AlzeCure Pharma AB Triazine derivatives for treating diseases relating to neurotrophins
US11840524B2 (en) 2018-06-28 2023-12-12 AlzeCure Pharma AB 4-substituted phenyl-1,3,5-triazine derivatives as modulators of TrK receptors

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2008009818A (es) 2008-07-31 2010-02-01 Avi Mex S A De C V Lab Combinacion coccidicida para uso veterinario.
DE102009012423A1 (de) 2009-03-10 2010-09-16 Bayer Animal Health Gmbh Zubereitung auf Ölbasis
DE102009038949A1 (de) * 2009-08-26 2011-03-03 Bayer Animal Health Gmbh Neue Verwendung von heterocyclisch substituierten 1,2,4-Triazindionen

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4631278A (en) * 1984-08-01 1986-12-23 Janssen Pharmaceutica N.V. Anti-protozoal α-aryl-4-(4,5-dihydro-3,5-dioxo-1,2,4-triazin-2(3H)-yl)-benzeneacetonitrile derivatives, pharmaceutical compositions, and method of use therefor
US4778887A (en) * 1984-08-01 1988-10-18 Janssen Pharmaceutica N.V. α-aryl-4-(4,5-dihydro-3,5-dioxo-1,2,4-triazin-2(3H)-yl)-benzeneacetonitriles
DE3805660A1 (de) * 1988-02-24 1989-09-07 Bayer Ag Substituierte 1,2,4-triazindione, verfahren zu ihrer herstellung und ihre verwendung
DE3826058A1 (de) * 1988-07-30 1990-02-08 Bayer Ag Mittel gegen fischparasiten
US5196562A (en) * 1988-10-08 1993-03-23 Bayer Aktiengesellschaft Substituted 1,3,5-triazinetriones, for use against parasitic protozoa
US4933341A (en) * 1988-10-08 1990-06-12 Bayer Aktiengesellschaft Substituted 1,3,5-triazinetriones, for use against parasitic protozoa
EP0377903A3 (de) * 1989-01-09 1991-07-17 Bayer Ag Substituierte Hexahydro-1,2,4-triazindione, Verfahren zu ihrer Herstellung, Zwischenprodukte dafür und ihre Verwendung
CN1044905A (zh) * 1989-02-16 1990-08-29 赫彻斯特股份公司 鱼和昆虫寄生虫对抗剂
DE4030042A1 (de) * 1990-05-17 1991-11-21 Bayer Ag Verwendung von substituierten 1,2,4-triazindionen
US5256632A (en) * 1990-05-30 1993-10-26 Bayer Aktiengesellschaft Herbicidal sulphonylated carboxamides
DE19519821A1 (de) * 1995-05-31 1996-12-05 Bayer Ag Mittel gegen parasitäre Protozoen
ATE271122T1 (de) * 1996-11-12 2004-07-15 Pfizer Attenuierter lebender neospora impfstoff
US5883095A (en) * 1997-08-07 1999-03-16 University Of Kentucky Research Foundation Formulations and methods to treat and prevent equine protozoal myeloencephalitis
WO1998043644A1 (en) * 1997-03-31 1998-10-08 David Granstrom Formulations and methods to treat and prevent equine protozoal myeloencephalitis
US5830893A (en) * 1997-04-23 1998-11-03 Mortar & Pestle Veterinary Pharmacy, Inc. Treatment of equine protozoan myeloencephalitis using triazinediones
ATE352315T1 (de) * 1997-10-20 2007-02-15 Bayer Corp Neospora impstoff
US6248329B1 (en) * 1998-06-01 2001-06-19 Ramaswamy Chandrashekar Parasitic helminth cuticlin nucleic acid molecules and uses thereof
BR9914385A (pt) * 1998-10-08 2001-07-17 New Ace Res Company Composição útil para o tratamento e prevenção de infecções protozoárias no homem e em animais, e, método de tratamento de uma infecção protozoária no homem e em animais
KR20010080571A (ko) * 1998-12-22 2001-08-22 조지 제이. 리코스 사르코시스티스, 네오스포라 및 톡소플라즈마에 의한 질병치료용 트리아진온 화합물
US6150361A (en) * 1998-12-22 2000-11-21 Bayer Corporation Triazineone compounds for treating diseases due to sarcosystis, neospora and toxoplasma
US6194408B1 (en) * 1998-12-22 2001-02-27 Bayer Corporation Triazineone compounds for treating diseases due to Sarcocystis, Neospora and Toxoplasma

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102007025908A1 (de) 2007-06-01 2008-12-04 Bayer Healthcare Ag Formulierungen enthaltend Triazinone und Eisen
EP3692993A1 (de) 2007-06-01 2020-08-12 Bayer Animal Health GmbH Formulierungen enthaltend triazinone und eisen
US11352332B2 (en) 2018-02-26 2022-06-07 AlzeCure Pharma AB Triazine derivatives for treating diseases relating to neurotrophins
US11840524B2 (en) 2018-06-28 2023-12-12 AlzeCure Pharma AB 4-substituted phenyl-1,3,5-triazine derivatives as modulators of TrK receptors

Also Published As

Publication number Publication date
CA2394188C (en) 2010-01-26
ES2243323T3 (es) 2005-12-01
HUP0203534A3 (en) 2003-10-28
HUP0203534A2 (hu) 2003-01-28
DE50010648D1 (de) 2005-08-04
ZA200203476B (en) 2003-05-02
WO2001039778A3 (de) 2002-01-31
EP1246624A2 (de) 2002-10-09
EP1246624B1 (de) 2005-06-29
CN101632676A (zh) 2010-01-27
US9399037B2 (en) 2016-07-26
HU226379B1 (en) 2008-10-28
WO2001039778A2 (de) 2001-06-07
DK1246624T3 (da) 2005-10-03
AU783437B2 (en) 2005-10-27
CA2394188A1 (en) 2001-06-07
JP5031163B2 (ja) 2012-09-19
BR0015996A (pt) 2002-08-06
CN1407893A (zh) 2003-04-02
AU1524401A (en) 2001-06-12
US20090181040A1 (en) 2009-07-16
NZ519327A (en) 2004-10-29
JP2003515563A (ja) 2003-05-07
MXPA02005479A (es) 2003-01-28
ATE298573T1 (de) 2005-07-15

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Legal Events

Date Code Title Description
8139 Disposal/non-payment of the annual fee