CN1394135A - 微生物包封的材料在化妆品最终配方中的应用 - Google Patents
微生物包封的材料在化妆品最终配方中的应用 Download PDFInfo
- Publication number
- CN1394135A CN1394135A CN01803582A CN01803582A CN1394135A CN 1394135 A CN1394135 A CN 1394135A CN 01803582 A CN01803582 A CN 01803582A CN 01803582 A CN01803582 A CN 01803582A CN 1394135 A CN1394135 A CN 1394135A
- Authority
- CN
- China
- Prior art keywords
- skin
- cosmetic
- end formulation
- microbial
- cosmetic end
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 67
- 239000000463 material Substances 0.000 title claims abstract description 59
- 239000002537 cosmetic Substances 0.000 title claims abstract description 50
- 238000009472 formulation Methods 0.000 title claims abstract description 30
- 240000004808 Saccharomyces cerevisiae Species 0.000 claims abstract description 25
- 238000002360 preparation method Methods 0.000 claims description 49
- 230000000813 microbial effect Effects 0.000 claims description 46
- 239000002775 capsule Substances 0.000 claims description 45
- 238000005538 encapsulation Methods 0.000 claims description 35
- 150000001875 compounds Chemical class 0.000 claims description 34
- 239000003921 oil Substances 0.000 claims description 30
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 claims description 27
- 239000007788 liquid Substances 0.000 claims description 21
- 239000000975 dye Substances 0.000 claims description 18
- 235000013599 spices Nutrition 0.000 claims description 18
- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 claims description 15
- 239000003795 chemical substances by application Substances 0.000 claims description 12
- 239000006071 cream Substances 0.000 claims description 12
- XEFQLINVKFYRCS-UHFFFAOYSA-N Triclosan Chemical compound OC1=CC(Cl)=CC=C1OC1=CC=C(Cl)C=C1Cl XEFQLINVKFYRCS-UHFFFAOYSA-N 0.000 claims description 10
- 229960003500 triclosan Drugs 0.000 claims description 10
- 230000000694 effects Effects 0.000 claims description 9
- 239000000839 emulsion Substances 0.000 claims description 9
- 150000003722 vitamin derivatives Chemical class 0.000 claims description 9
- 238000005406 washing Methods 0.000 claims description 8
- 239000000516 sunscreening agent Substances 0.000 claims description 7
- 229940088594 vitamin Drugs 0.000 claims description 7
- 229930003231 vitamin Natural products 0.000 claims description 7
- 235000013343 vitamin Nutrition 0.000 claims description 7
- 239000011782 vitamin Substances 0.000 claims description 7
- 239000000284 extract Substances 0.000 claims description 6
- 239000000843 powder Substances 0.000 claims description 6
- 230000000475 sunscreen effect Effects 0.000 claims description 6
- 239000003963 antioxidant agent Substances 0.000 claims description 5
- 230000003078 antioxidant effect Effects 0.000 claims description 5
- 230000003760 hair shine Effects 0.000 claims description 5
- 230000000474 nursing effect Effects 0.000 claims description 5
- 238000004332 deodorization Methods 0.000 claims description 4
- 238000001914 filtration Methods 0.000 claims description 4
- 239000002304 perfume Substances 0.000 claims description 4
- 239000000080 wetting agent Substances 0.000 claims description 4
- 230000002087 whitening effect Effects 0.000 claims description 4
- 241001465754 Metazoa Species 0.000 claims description 3
- 239000000443 aerosol Substances 0.000 claims description 3
- 230000000845 anti-microbial effect Effects 0.000 claims description 3
- 125000003963 dichloro group Chemical group Cl* 0.000 claims description 3
- 238000011049 filling Methods 0.000 claims description 3
- 210000004905 finger nail Anatomy 0.000 claims description 3
- 201000000909 keratomalacia Diseases 0.000 claims description 3
- 230000007246 mechanism Effects 0.000 claims description 3
- 239000000419 plant extract Substances 0.000 claims description 3
- 230000008439 repair process Effects 0.000 claims description 3
- 238000005507 spraying Methods 0.000 claims description 3
- 239000000126 substance Substances 0.000 claims description 3
- 241000238631 Hexapoda Species 0.000 claims description 2
- 239000004922 lacquer Substances 0.000 claims description 2
- 210000002200 mouth mucosa Anatomy 0.000 claims description 2
- 235000011837 pasties Nutrition 0.000 claims description 2
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 33
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 30
- 235000019198 oils Nutrition 0.000 description 28
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 25
- 235000014680 Saccharomyces cerevisiae Nutrition 0.000 description 23
- PUZPDOWCWNUUKD-UHFFFAOYSA-M sodium fluoride Chemical compound [F-].[Na+] PUZPDOWCWNUUKD-UHFFFAOYSA-M 0.000 description 18
- -1 stearyl trihydroxyethyl trimethylene Chemical group 0.000 description 18
- 239000011734 sodium Substances 0.000 description 17
- 229910052708 sodium Inorganic materials 0.000 description 17
- 239000000243 solution Substances 0.000 description 17
- 229960003742 phenol Drugs 0.000 description 13
- 235000011187 glycerol Nutrition 0.000 description 12
- 239000012153 distilled water Substances 0.000 description 11
- 239000000499 gel Substances 0.000 description 11
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Natural products OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 10
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 10
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 10
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 description 9
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 description 9
- 238000011010 flushing procedure Methods 0.000 description 9
- 238000007789 sealing Methods 0.000 description 9
- 239000011775 sodium fluoride Substances 0.000 description 9
- 235000013024 sodium fluoride Nutrition 0.000 description 9
- 238000003756 stirring Methods 0.000 description 9
- 239000000606 toothpaste Substances 0.000 description 9
- 229940034610 toothpaste Drugs 0.000 description 9
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 description 8
- 235000019820 disodium diphosphate Nutrition 0.000 description 8
- GYQBBRRVRKFJRG-UHFFFAOYSA-L disodium pyrophosphate Chemical class [Na+].[Na+].OP([O-])(=O)OP(O)([O-])=O GYQBBRRVRKFJRG-UHFFFAOYSA-L 0.000 description 8
- YGSDEFSMJLZEOE-UHFFFAOYSA-N salicylic acid Chemical class OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 description 8
- FQENQNTWSFEDLI-UHFFFAOYSA-J sodium diphosphate Chemical class [Na+].[Na+].[Na+].[Na+].[O-]P([O-])(=O)OP([O-])([O-])=O FQENQNTWSFEDLI-UHFFFAOYSA-J 0.000 description 8
- 235000019818 tetrasodium diphosphate Nutrition 0.000 description 8
- ALYNCZNDIQEVRV-UHFFFAOYSA-N 4-aminobenzoic acid Chemical compound NC1=CC=C(C(O)=O)C=C1 ALYNCZNDIQEVRV-UHFFFAOYSA-N 0.000 description 7
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 7
- 230000000507 anthelmentic effect Effects 0.000 description 7
- FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 description 7
- 239000007787 solid Substances 0.000 description 7
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 description 6
- 229920001661 Chitosan Polymers 0.000 description 6
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 6
- 241001597008 Nomeidae Species 0.000 description 6
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 6
- 238000004140 cleaning Methods 0.000 description 6
- 229940038485 disodium pyrophosphate Drugs 0.000 description 6
- NUVBSKCKDOMJSU-UHFFFAOYSA-N ethylparaben Chemical compound CCOC(=O)C1=CC=C(O)C=C1 NUVBSKCKDOMJSU-UHFFFAOYSA-N 0.000 description 6
- 210000002683 foot Anatomy 0.000 description 6
- 239000002904 solvent Substances 0.000 description 6
- 229920003171 Poly (ethylene oxide) Polymers 0.000 description 5
- 239000002250 absorbent Substances 0.000 description 5
- 230000002745 absorbent Effects 0.000 description 5
- 230000035617 depilation Effects 0.000 description 5
- 244000005700 microbiome Species 0.000 description 5
- 239000002480 mineral oil Substances 0.000 description 5
- 235000010446 mineral oil Nutrition 0.000 description 5
- 210000000214 mouth Anatomy 0.000 description 5
- 239000000377 silicon dioxide Substances 0.000 description 5
- 239000010677 tea tree oil Substances 0.000 description 5
- 229940111630 tea tree oil Drugs 0.000 description 5
- 125000002889 tridecyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 5
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 4
- 241000628997 Flos Species 0.000 description 4
- 241001062009 Indigofera Species 0.000 description 4
- XLOUUCCGSNMHHQ-UHFFFAOYSA-N OP(O)(O)=O.CCCCCCCCCCCC[Na] Chemical class OP(O)(O)=O.CCCCCCCCCCCC[Na] XLOUUCCGSNMHHQ-UHFFFAOYSA-N 0.000 description 4
- 235000006708 antioxidants Nutrition 0.000 description 4
- 239000003213 antiperspirant Substances 0.000 description 4
- 230000015572 biosynthetic process Effects 0.000 description 4
- 229920001577 copolymer Polymers 0.000 description 4
- RXKJFZQQPQGTFL-UHFFFAOYSA-N dihydroxyacetone Chemical compound OCC(=O)CO RXKJFZQQPQGTFL-UHFFFAOYSA-N 0.000 description 4
- 150000002148 esters Chemical class 0.000 description 4
- OVBPIULPVIDEAO-LBPRGKRZSA-N folic acid Chemical compound C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-LBPRGKRZSA-N 0.000 description 4
- 150000002632 lipids Chemical class 0.000 description 4
- 229920001983 poloxamer Polymers 0.000 description 4
- 239000003223 protective agent Substances 0.000 description 4
- GHMLBKRAJCXXBS-UHFFFAOYSA-N resorcinyl group Chemical group C1(O)=CC(O)=CC=C1 GHMLBKRAJCXXBS-UHFFFAOYSA-N 0.000 description 4
- 210000000582 semen Anatomy 0.000 description 4
- 239000002453 shampoo Substances 0.000 description 4
- 239000000344 soap Substances 0.000 description 4
- 229940047670 sodium acrylate Drugs 0.000 description 4
- 239000007921 spray Substances 0.000 description 4
- 239000004408 titanium dioxide Substances 0.000 description 4
- DSSYKIVIOFKYAU-XCBNKYQSSA-N (R)-camphor Chemical class C1C[C@@]2(C)C(=O)C[C@@H]1C2(C)C DSSYKIVIOFKYAU-XCBNKYQSSA-N 0.000 description 3
- JYEUMXHLPRZUAT-UHFFFAOYSA-N 1,2,3-triazine Chemical compound C1=CN=NN=C1 JYEUMXHLPRZUAT-UHFFFAOYSA-N 0.000 description 3
- NIXOWILDQLNWCW-UHFFFAOYSA-N Acrylic acid Chemical compound OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 3
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 description 3
- VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 description 3
- YCKRFDGAMUMZLT-UHFFFAOYSA-N Fluorine atom Chemical compound [F] YCKRFDGAMUMZLT-UHFFFAOYSA-N 0.000 description 3
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 3
- 244000025272 Persea americana Species 0.000 description 3
- 229920002125 Sokalan® Polymers 0.000 description 3
- FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 description 3
- 229930003427 Vitamin E Natural products 0.000 description 3
- 239000002253 acid Substances 0.000 description 3
- 230000001476 alcoholic effect Effects 0.000 description 3
- 125000005210 alkyl ammonium group Chemical group 0.000 description 3
- 235000011399 aloe vera Nutrition 0.000 description 3
- 230000001166 anti-perspirative effect Effects 0.000 description 3
- 235000010323 ascorbic acid Nutrition 0.000 description 3
- 229960005070 ascorbic acid Drugs 0.000 description 3
- 239000011668 ascorbic acid Substances 0.000 description 3
- 230000008901 benefit Effects 0.000 description 3
- 239000012964 benzotriazole Substances 0.000 description 3
- 229960001631 carbomer Drugs 0.000 description 3
- 235000013870 dimethyl polysiloxane Nutrition 0.000 description 3
- 239000000986 disperse dye Substances 0.000 description 3
- 235000010228 ethyl p-hydroxybenzoate Nutrition 0.000 description 3
- 239000004403 ethyl p-hydroxybenzoate Substances 0.000 description 3
- 230000001815 facial effect Effects 0.000 description 3
- 239000011737 fluorine Substances 0.000 description 3
- 229910052731 fluorine Inorganic materials 0.000 description 3
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 description 3
- LXCFILQKKLGQFO-UHFFFAOYSA-N methylparaben Chemical compound COC(=O)C1=CC=C(O)C=C1 LXCFILQKKLGQFO-UHFFFAOYSA-N 0.000 description 3
- 238000002156 mixing Methods 0.000 description 3
- 239000002324 mouth wash Substances 0.000 description 3
- 229940051866 mouthwash Drugs 0.000 description 3
- ZVVSSOQAYNYNPP-UHFFFAOYSA-N olaflur Chemical compound F.F.CCCCCCCCCCCCCCCCCCN(CCO)CCCN(CCO)CCO ZVVSSOQAYNYNPP-UHFFFAOYSA-N 0.000 description 3
- 239000006072 paste Substances 0.000 description 3
- 239000012071 phase Substances 0.000 description 3
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 description 3
- 229960003471 retinol Drugs 0.000 description 3
- 235000020944 retinol Nutrition 0.000 description 3
- 239000011607 retinol Substances 0.000 description 3
- 229960004889 salicylic acid Drugs 0.000 description 3
- 150000003839 salts Chemical class 0.000 description 3
- PESXGULMKCKJCC-UHFFFAOYSA-M sodium;4-methoxycarbonylphenolate Chemical compound [Na+].COC(=O)C1=CC=C([O-])C=C1 PESXGULMKCKJCC-UHFFFAOYSA-M 0.000 description 3
- IXMINYBUNCWGER-UHFFFAOYSA-M sodium;4-propoxycarbonylphenolate Chemical compound [Na+].CCCOC(=O)C1=CC=C([O-])C=C1 IXMINYBUNCWGER-UHFFFAOYSA-M 0.000 description 3
- 239000000600 sorbitol Substances 0.000 description 3
- 235000010356 sorbitol Nutrition 0.000 description 3
- 238000000967 suction filtration Methods 0.000 description 3
- CXVGEDCSTKKODG-UHFFFAOYSA-N sulisobenzone Chemical compound C1=C(S(O)(=O)=O)C(OC)=CC(O)=C1C(=O)C1=CC=CC=C1 CXVGEDCSTKKODG-UHFFFAOYSA-N 0.000 description 3
- 229960000368 sulisobenzone Drugs 0.000 description 3
- 239000000271 synthetic detergent Substances 0.000 description 3
- 229930003799 tocopherol Natural products 0.000 description 3
- 235000010384 tocopherol Nutrition 0.000 description 3
- 229960001295 tocopherol Drugs 0.000 description 3
- 239000011732 tocopherol Substances 0.000 description 3
- 235000019155 vitamin A Nutrition 0.000 description 3
- 239000011719 vitamin A Substances 0.000 description 3
- 235000019165 vitamin E Nutrition 0.000 description 3
- 239000011709 vitamin E Substances 0.000 description 3
- 229940045997 vitamin a Drugs 0.000 description 3
- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 description 3
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 description 2
- FYGDTMLNYKFZSV-URKRLVJHSA-N (2s,3r,4s,5s,6r)-2-[(2r,4r,5r,6s)-4,5-dihydroxy-2-(hydroxymethyl)-6-[(2r,4r,5r,6s)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1[C@@H](CO)O[C@@H](OC2[C@H](O[C@H](O)[C@H](O)[C@H]2O)CO)[C@H](O)[C@H]1O FYGDTMLNYKFZSV-URKRLVJHSA-N 0.000 description 2
- GHOKWGTUZJEAQD-ZETCQYMHSA-N (D)-(+)-Pantothenic acid Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-ZETCQYMHSA-N 0.000 description 2
- AFDXODALSZRGIH-QPJJXVBHSA-N (E)-3-(4-methoxyphenyl)prop-2-enoic acid Chemical compound COC1=CC=C(\C=C\C(O)=O)C=C1 AFDXODALSZRGIH-QPJJXVBHSA-N 0.000 description 2
- OCQDPIXQTSYZJL-UHFFFAOYSA-N 1,4-bis(butylamino)anthracene-9,10-dione Chemical compound O=C1C2=CC=CC=C2C(=O)C2=C1C(NCCCC)=CC=C2NCCCC OCQDPIXQTSYZJL-UHFFFAOYSA-N 0.000 description 2
- FBMQNRKSAWNXBT-UHFFFAOYSA-N 1,4-diaminoanthracene-9,10-dione Chemical compound O=C1C2=CC=CC=C2C(=O)C2=C1C(N)=CC=C2N FBMQNRKSAWNXBT-UHFFFAOYSA-N 0.000 description 2
- NLXFWUZKOOWWFD-UHFFFAOYSA-N 1-(2-hydroxyethylamino)-4-(methylamino)anthracene-9,10-dione Chemical compound O=C1C2=CC=CC=C2C(=O)C2=C1C(NCCO)=CC=C2NC NLXFWUZKOOWWFD-UHFFFAOYSA-N 0.000 description 2
- ICVRBKCRXNVOJC-UHFFFAOYSA-N 1-amino-4-(methylamino)anthracene-9,10-dione Chemical compound O=C1C2=CC=CC=C2C(=O)C2=C1C(N)=CC=C2NC ICVRBKCRXNVOJC-UHFFFAOYSA-N 0.000 description 2
- HXXLWTPFYWMBSC-UHFFFAOYSA-N 2-[3-chloro-4-[(2,6-dichloro-4-nitrophenyl)diazenyl]-n-(2-hydroxyethyl)anilino]ethanol Chemical compound ClC1=CC(N(CCO)CCO)=CC=C1N=NC1=C(Cl)C=C([N+]([O-])=O)C=C1Cl HXXLWTPFYWMBSC-UHFFFAOYSA-N 0.000 description 2
- WXGKXLXGYOYZMX-UHFFFAOYSA-N 2-[4-(2-aminoethylamino)-3-nitrophenoxy]ethanol Chemical compound NCCNC1=CC=C(OCCO)C=C1[N+]([O-])=O WXGKXLXGYOYZMX-UHFFFAOYSA-N 0.000 description 2
- WMJBVALTYVXGHW-UHFFFAOYSA-N 3,3-diphenylprop-2-enoic acid Chemical compound C=1C=CC=CC=1C(=CC(=O)O)C1=CC=CC=C1 WMJBVALTYVXGHW-UHFFFAOYSA-N 0.000 description 2
- SZWQTBKBBNGUAB-UHFFFAOYSA-N 3-[4-(2-hydroxyethylamino)-3-nitrophenoxy]propane-1,2-diol Chemical compound OCCNC1=CC=C(OCC(O)CO)C=C1[N+]([O-])=O SZWQTBKBBNGUAB-UHFFFAOYSA-N 0.000 description 2
- ZDTNHRWWURISAA-UHFFFAOYSA-N 4',5'-dibromo-3',6'-dihydroxyspiro[2-benzofuran-3,9'-xanthene]-1-one Chemical compound O1C(=O)C2=CC=CC=C2C21C1=CC=C(O)C(Br)=C1OC1=C(Br)C(O)=CC=C21 ZDTNHRWWURISAA-UHFFFAOYSA-N 0.000 description 2
- HSDSBIUUVWRHTM-UHFFFAOYSA-N 4-(2-nitroanilino)phenol Chemical compound C1=CC(O)=CC=C1NC1=CC=CC=C1[N+]([O-])=O HSDSBIUUVWRHTM-UHFFFAOYSA-N 0.000 description 2
- UNBOSJFEZZJZLR-UHFFFAOYSA-N 4-(4-nitrophenylazo)aniline Chemical compound C1=CC(N)=CC=C1N=NC1=CC=C([N+]([O-])=O)C=C1 UNBOSJFEZZJZLR-UHFFFAOYSA-N 0.000 description 2
- 229940090248 4-hydroxybenzoic acid Drugs 0.000 description 2
- BPTKLSBRRJFNHJ-UHFFFAOYSA-N 4-phenyldiazenylbenzene-1,3-diol Chemical compound OC1=CC(O)=CC=C1N=NC1=CC=CC=C1 BPTKLSBRRJFNHJ-UHFFFAOYSA-N 0.000 description 2
- FQLZTPSAVDHUKS-UHFFFAOYSA-N 6-amino-2-(2,4-dimethylphenyl)benzo[de]isoquinoline-1,3-dione Chemical compound CC1=CC(C)=CC=C1N(C1=O)C(=O)C2=C3C1=CC=CC3=C(N)C=C2 FQLZTPSAVDHUKS-UHFFFAOYSA-N 0.000 description 2
- 235000019489 Almond oil Nutrition 0.000 description 2
- 244000144927 Aloe barbadensis Species 0.000 description 2
- 235000002961 Aloe barbadensis Nutrition 0.000 description 2
- 229920002498 Beta-glucan Polymers 0.000 description 2
- 240000003538 Chamaemelum nobile Species 0.000 description 2
- 235000007866 Chamaemelum nobile Nutrition 0.000 description 2
- ZAKOWWREFLAJOT-CEFNRUSXSA-N D-alpha-tocopherylacetate Chemical compound CC(=O)OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C ZAKOWWREFLAJOT-CEFNRUSXSA-N 0.000 description 2
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 description 2
- JSFUMBWFPQSADC-UHFFFAOYSA-N Disperse Blue 1 Chemical compound O=C1C2=C(N)C=CC(N)=C2C(=O)C2=C1C(N)=CC=C2N JSFUMBWFPQSADC-UHFFFAOYSA-N 0.000 description 2
- 241000233866 Fungi Species 0.000 description 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 description 2
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 description 2
- QIGBRXMKCJKVMJ-UHFFFAOYSA-N Hydroquinone Chemical compound OC1=CC=C(O)C=C1 QIGBRXMKCJKVMJ-UHFFFAOYSA-N 0.000 description 2
- COHYTHOBJLSHDF-UHFFFAOYSA-N Indigo Chemical compound N1C2=CC=CC=C2C(=O)C1=C1C(=O)C2=CC=CC=C2N1 COHYTHOBJLSHDF-UHFFFAOYSA-N 0.000 description 2
- 235000007232 Matricaria chamomilla Nutrition 0.000 description 2
- XUMBMVFBXHLACL-UHFFFAOYSA-N Melanin Chemical compound O=C1C(=O)C(C2=CNC3=C(C(C(=O)C4=C32)=O)C)=C2C4=CNC2=C1C XUMBMVFBXHLACL-UHFFFAOYSA-N 0.000 description 2
- OVBPIULPVIDEAO-UHFFFAOYSA-N N-Pteroyl-L-glutaminsaeure Natural products C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)NC(CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-UHFFFAOYSA-N 0.000 description 2
- 235000011236 Persea americana var americana Nutrition 0.000 description 2
- SMWDFEZZVXVKRB-UHFFFAOYSA-N Quinoline Chemical compound N1=CC=CC2=CC=CC=C21 SMWDFEZZVXVKRB-UHFFFAOYSA-N 0.000 description 2
- 244000044822 Simmondsia californica Species 0.000 description 2
- 235000004433 Simmondsia californica Nutrition 0.000 description 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- YCUVUDODLRLVIC-UHFFFAOYSA-N Sudan black B Chemical compound C1=CC(=C23)NC(C)(C)NC2=CC=CC3=C1N=NC(C1=CC=CC=C11)=CC=C1N=NC1=CC=CC=C1 YCUVUDODLRLVIC-UHFFFAOYSA-N 0.000 description 2
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 2
- 229930003268 Vitamin C Natural products 0.000 description 2
- 239000013543 active substance Substances 0.000 description 2
- 239000000853 adhesive Substances 0.000 description 2
- 230000001070 adhesive effect Effects 0.000 description 2
- 150000001298 alcohols Chemical class 0.000 description 2
- 239000008168 almond oil Substances 0.000 description 2
- 235000001014 amino acid Nutrition 0.000 description 2
- 150000001413 amino acids Chemical class 0.000 description 2
- 230000000844 anti-bacterial effect Effects 0.000 description 2
- 125000000751 azo group Chemical group [*]N=N[*] 0.000 description 2
- RWCCWEUUXYIKHB-UHFFFAOYSA-N benzophenone Chemical compound C=1C=CC=CC=1C(=O)C1=CC=CC=C1 RWCCWEUUXYIKHB-UHFFFAOYSA-N 0.000 description 2
- 239000012965 benzophenone Substances 0.000 description 2
- QRUDEWIWKLJBPS-UHFFFAOYSA-N benzotriazole Chemical compound C1=CC=C2N[N][N]C2=C1 QRUDEWIWKLJBPS-UHFFFAOYSA-N 0.000 description 2
- BEWYHVAWEKZDPP-UHFFFAOYSA-N bornane Chemical compound C1CC2(C)CCC1C2(C)C BEWYHVAWEKZDPP-UHFFFAOYSA-N 0.000 description 2
- DBZJJPROPLPMSN-UHFFFAOYSA-N bromoeosin Chemical compound O1C(=O)C2=CC=CC=C2C21C1=CC(Br)=C(O)C(Br)=C1OC1=C(Br)C(O)=C(Br)C=C21 DBZJJPROPLPMSN-UHFFFAOYSA-N 0.000 description 2
- 239000002738 chelating agent Substances 0.000 description 2
- 239000012459 cleaning agent Substances 0.000 description 2
- 239000003086 colorant Substances 0.000 description 2
- 238000004040 coloring Methods 0.000 description 2
- 150000001907 coumarones Chemical class 0.000 description 2
- 239000008367 deionised water Substances 0.000 description 2
- 229910021641 deionized water Inorganic materials 0.000 description 2
- 239000000551 dentifrice Substances 0.000 description 2
- 239000002781 deodorant agent Substances 0.000 description 2
- NZZIMKJIVMHWJC-UHFFFAOYSA-N dibenzoylmethane Chemical class C=1C=CC=CC=1C(=O)CC(=O)C1=CC=CC=C1 NZZIMKJIVMHWJC-UHFFFAOYSA-N 0.000 description 2
- 229940120503 dihydroxyacetone Drugs 0.000 description 2
- 229940008099 dimethicone Drugs 0.000 description 2
- 239000004205 dimethyl polysiloxane Substances 0.000 description 2
- USIUVYZYUHIAEV-UHFFFAOYSA-N diphenyl ether Chemical compound C=1C=CC=CC=1OC1=CC=CC=C1 USIUVYZYUHIAEV-UHFFFAOYSA-N 0.000 description 2
- 239000006185 dispersion Substances 0.000 description 2
- 229960001617 ethyl hydroxybenzoate Drugs 0.000 description 2
- 239000006260 foam Substances 0.000 description 2
- 229960000304 folic acid Drugs 0.000 description 2
- 235000019152 folic acid Nutrition 0.000 description 2
- 239000011724 folic acid Substances 0.000 description 2
- 150000002333 glycines Chemical class 0.000 description 2
- 239000000118 hair dye Substances 0.000 description 2
- IIRDTKBZINWQAW-UHFFFAOYSA-N hexaethylene glycol Chemical compound OCCOCCOCCOCCOCCOCCO IIRDTKBZINWQAW-UHFFFAOYSA-N 0.000 description 2
- 239000003906 humectant Substances 0.000 description 2
- 239000001257 hydrogen Substances 0.000 description 2
- 229910052739 hydrogen Inorganic materials 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 2
- 239000007791 liquid phase Substances 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 235000010270 methyl p-hydroxybenzoate Nutrition 0.000 description 2
- 239000004292 methyl p-hydroxybenzoate Substances 0.000 description 2
- 229960002216 methylparaben Drugs 0.000 description 2
- 239000003094 microcapsule Substances 0.000 description 2
- 230000007935 neutral effect Effects 0.000 description 2
- 229910052757 nitrogen Inorganic materials 0.000 description 2
- 239000010466 nut oil Substances 0.000 description 2
- AFDXODALSZRGIH-UHFFFAOYSA-N p-coumaric acid methyl ether Natural products COC1=CC=C(C=CC(O)=O)C=C1 AFDXODALSZRGIH-UHFFFAOYSA-N 0.000 description 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 2
- ZYIBVBKZZZDFOY-UHFFFAOYSA-N phloxine O Chemical compound O1C(=O)C(C(=C(Cl)C(Cl)=C2Cl)Cl)=C2C21C1=CC(Br)=C(O)C(Br)=C1OC1=C(Br)C(O)=C(Br)C=C21 ZYIBVBKZZZDFOY-UHFFFAOYSA-N 0.000 description 2
- 229920002401 polyacrylamide Polymers 0.000 description 2
- 235000010232 propyl p-hydroxybenzoate Nutrition 0.000 description 2
- QELSKZZBTMNZEB-UHFFFAOYSA-N propylparaben Chemical compound CCCOC(=O)C1=CC=C(O)C=C1 QELSKZZBTMNZEB-UHFFFAOYSA-N 0.000 description 2
- 230000005855 radiation Effects 0.000 description 2
- DCKVNWZUADLDEH-UHFFFAOYSA-N sec-butyl acetate Chemical compound CCC(C)OC(C)=O DCKVNWZUADLDEH-UHFFFAOYSA-N 0.000 description 2
- 239000008257 shaving cream Substances 0.000 description 2
- 229920002545 silicone oil Polymers 0.000 description 2
- 229940057950 sodium laureth sulfate Drugs 0.000 description 2
- SXHLENDCVBIJFO-UHFFFAOYSA-M sodium;2-[2-(2-dodecoxyethoxy)ethoxy]ethyl sulfate Chemical compound [Na+].CCCCCCCCCCCCOCCOCCOCCOS([O-])(=O)=O SXHLENDCVBIJFO-UHFFFAOYSA-M 0.000 description 2
- 239000000992 solvent dye Substances 0.000 description 2
- 238000001694 spray drying Methods 0.000 description 2
- 239000002562 thickening agent Substances 0.000 description 2
- 229940042585 tocopherol acetate Drugs 0.000 description 2
- QAIPRVGONGVQAS-DUXPYHPUSA-N trans-caffeic acid Chemical compound OC(=O)\C=C\C1=CC=C(O)C(O)=C1 QAIPRVGONGVQAS-DUXPYHPUSA-N 0.000 description 2
- WBYWAXJHAXSJNI-VOTSOKGWSA-M trans-cinnamate Chemical compound [O-]C(=O)\C=C\C1=CC=CC=C1 WBYWAXJHAXSJNI-VOTSOKGWSA-M 0.000 description 2
- 235000015112 vegetable and seed oil Nutrition 0.000 description 2
- 239000008158 vegetable oil Substances 0.000 description 2
- 235000019154 vitamin C Nutrition 0.000 description 2
- 239000011718 vitamin C Substances 0.000 description 2
- 229940046009 vitamin E Drugs 0.000 description 2
- HEOCBCNFKCOKBX-RELGSGGGSA-N (1s,2e,4r)-4,7,7-trimethyl-2-[(4-methylphenyl)methylidene]bicyclo[2.2.1]heptan-3-one Chemical compound C1=CC(C)=CC=C1\C=C/1C(=O)[C@]2(C)CC[C@H]\1C2(C)C HEOCBCNFKCOKBX-RELGSGGGSA-N 0.000 description 1
- FTLYMKDSHNWQKD-UHFFFAOYSA-N (2,4,5-trichlorophenyl)boronic acid Chemical compound OB(O)C1=CC(Cl)=C(Cl)C=C1Cl FTLYMKDSHNWQKD-UHFFFAOYSA-N 0.000 description 1
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 description 1
- OIQXFRANQVWXJF-QBFSEMIESA-N (2z)-2-benzylidene-4,7,7-trimethylbicyclo[2.2.1]heptan-3-one Chemical compound CC1(C)C2CCC1(C)C(=O)\C2=C/C1=CC=CC=C1 OIQXFRANQVWXJF-QBFSEMIESA-N 0.000 description 1
- ACEAELOMUCBPJP-UHFFFAOYSA-N (E)-3,4,5-trihydroxycinnamic acid Natural products OC(=O)C=CC1=CC(O)=C(O)C(O)=C1 ACEAELOMUCBPJP-UHFFFAOYSA-N 0.000 description 1
- NWUYHJFMYQTDRP-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;1-ethenyl-2-ethylbenzene;styrene Chemical compound C=CC1=CC=CC=C1.CCC1=CC=CC=C1C=C.C=CC1=CC=CC=C1C=C NWUYHJFMYQTDRP-UHFFFAOYSA-N 0.000 description 1
- BCMCBBGGLRIHSE-UHFFFAOYSA-N 1,3-benzoxazole Chemical compound C1=CC=C2OC=NC2=C1 BCMCBBGGLRIHSE-UHFFFAOYSA-N 0.000 description 1
- AQNZDXHBYRTSHA-UHFFFAOYSA-N 1,4-bis(2,3-dihydroxypropylamino)anthracene-9,10-dione Chemical compound O=C1C2=CC=CC=C2C(=O)C2=C1C(NCC(O)CO)=CC=C2NCC(O)CO AQNZDXHBYRTSHA-UHFFFAOYSA-N 0.000 description 1
- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 description 1
- KLCDQSGLLRINHY-UHFFFAOYSA-N 1-phenyldiazenylnaphthalen-2-amine Chemical compound NC1=CC=C2C=CC=CC2=C1N=NC1=CC=CC=C1 KLCDQSGLLRINHY-UHFFFAOYSA-N 0.000 description 1
- ZEMPKEQAKRGZGQ-AAKVHIHISA-N 2,3-bis[[(z)-12-hydroxyoctadec-9-enoyl]oxy]propyl (z)-12-hydroxyoctadec-9-enoate Chemical compound CCCCCCC(O)C\C=C/CCCCCCCC(=O)OCC(OC(=O)CCCCCCC\C=C/CC(O)CCCCCC)COC(=O)CCCCCCC\C=C/CC(O)CCCCCC ZEMPKEQAKRGZGQ-AAKVHIHISA-N 0.000 description 1
- VHWSRELATOUTAG-UHFFFAOYSA-N 2,3-dihydroxypropyl 2-aminobenzoate Chemical compound NC1=CC=CC=C1C(=O)OCC(O)CO VHWSRELATOUTAG-UHFFFAOYSA-N 0.000 description 1
- UHOPWFKONJYLCF-UHFFFAOYSA-N 2-(2-sulfanylethyl)isoindole-1,3-dione Chemical compound C1=CC=C2C(=O)N(CCS)C(=O)C2=C1 UHOPWFKONJYLCF-UHFFFAOYSA-N 0.000 description 1
- QWVUXEBWAZOACQ-UHFFFAOYSA-N 2-(hydroxymethyl)-2-[[2-hydroxy-3-(16-methylheptadecoxy)propoxy]methyl]propane-1,3-diol Chemical compound CC(C)CCCCCCCCCCCCCCCOCC(O)COCC(CO)(CO)CO QWVUXEBWAZOACQ-UHFFFAOYSA-N 0.000 description 1
- HZAXFHJVJLSVMW-UHFFFAOYSA-N 2-Aminoethan-1-ol Chemical compound NCCO HZAXFHJVJLSVMW-UHFFFAOYSA-N 0.000 description 1
- NZKTVPCPQIEVQT-UHFFFAOYSA-N 2-[4-[(4-aminophenyl)diazenyl]-n-(2-hydroxyethyl)anilino]ethanol Chemical compound C1=CC(N)=CC=C1N=NC1=CC=C(N(CCO)CCO)C=C1 NZKTVPCPQIEVQT-UHFFFAOYSA-N 0.000 description 1
- BZYZOJIGZUACMS-UHFFFAOYSA-N 2-[4-[bis(2-hydroxyethyl)amino]anilino]-5-(2-hydroxyethylamino)cyclohexa-2,5-diene-1,4-dione Chemical compound O=C1C(NCCO)=CC(=O)C(NC=2C=CC(=CC=2)N(CCO)CCO)=C1 BZYZOJIGZUACMS-UHFFFAOYSA-N 0.000 description 1
- POAOYUHQDCAZBD-UHFFFAOYSA-N 2-butoxyethanol Chemical compound CCCCOCCO POAOYUHQDCAZBD-UHFFFAOYSA-N 0.000 description 1
- JGUMTYWKIBJSTN-UHFFFAOYSA-N 2-ethylhexyl 4-[[4,6-bis[4-(2-ethylhexoxycarbonyl)anilino]-1,3,5-triazin-2-yl]amino]benzoate Chemical compound C1=CC(C(=O)OCC(CC)CCCC)=CC=C1NC1=NC(NC=2C=CC(=CC=2)C(=O)OCC(CC)CCCC)=NC(NC=2C=CC(=CC=2)C(=O)OCC(CC)CCCC)=N1 JGUMTYWKIBJSTN-UHFFFAOYSA-N 0.000 description 1
- UBVSIAHUTXHQTD-UHFFFAOYSA-N 2-n-(4-bromophenyl)-1,3,5-triazine-2,4-diamine Chemical compound NC1=NC=NC(NC=2C=CC(Br)=CC=2)=N1 UBVSIAHUTXHQTD-UHFFFAOYSA-N 0.000 description 1
- RUKISNQKOIKZGT-UHFFFAOYSA-N 2-nitrodiphenylamine Chemical compound [O-][N+](=O)C1=CC=CC=C1NC1=CC=CC=C1 RUKISNQKOIKZGT-UHFFFAOYSA-N 0.000 description 1
- QCDWFXQBSFUVSP-UHFFFAOYSA-N 2-phenoxyethanol Chemical compound OCCOC1=CC=CC=C1 QCDWFXQBSFUVSP-UHFFFAOYSA-N 0.000 description 1
- DZNJMLVCIZGWSC-UHFFFAOYSA-N 3',6'-bis(diethylamino)spiro[2-benzofuran-3,9'-xanthene]-1-one Chemical compound O1C(=O)C2=CC=CC=C2C21C1=CC=C(N(CC)CC)C=C1OC1=CC(N(CC)CC)=CC=C21 DZNJMLVCIZGWSC-UHFFFAOYSA-N 0.000 description 1
- HJLGQPREWJFXII-UHFFFAOYSA-N 4-(1-benzofuran-2-yl)aniline Chemical compound C1=CC(N)=CC=C1C1=CC2=CC=CC=C2O1 HJLGQPREWJFXII-UHFFFAOYSA-N 0.000 description 1
- CYDQOEWLBCCFJZ-UHFFFAOYSA-N 4-(4-fluorophenyl)oxane-4-carboxylic acid Chemical compound C=1C=C(F)C=CC=1C1(C(=O)O)CCOCC1 CYDQOEWLBCCFJZ-UHFFFAOYSA-N 0.000 description 1
- YDIYEOMDOWUDTJ-UHFFFAOYSA-N 4-(dimethylamino)benzoic acid Chemical compound CN(C)C1=CC=C(C(O)=O)C=C1 YDIYEOMDOWUDTJ-UHFFFAOYSA-N 0.000 description 1
- KLQVCADYSBUVAV-UHFFFAOYSA-N 4-[(2,4-dimethylphenyl)diazenyl]-5-methyl-2-phenyl-4h-pyrazol-3-one Chemical compound CC1=NN(C=2C=CC=CC=2)C(=O)C1N=NC1=CC=C(C)C=C1C KLQVCADYSBUVAV-UHFFFAOYSA-N 0.000 description 1
- KKJKXQYVUVWWJP-JLHYYAGUSA-N 4-[(e)-(4,7,7-trimethyl-3-oxo-2-bicyclo[2.2.1]heptanylidene)methyl]benzenesulfonic acid Chemical compound CC1(C)C2CCC1(C)C(=O)\C2=C\C1=CC=C(S(O)(=O)=O)C=C1 KKJKXQYVUVWWJP-JLHYYAGUSA-N 0.000 description 1
- DDFHBQSCUXNBSA-UHFFFAOYSA-N 5-(5-carboxythiophen-2-yl)thiophene-2-carboxylic acid Chemical compound S1C(C(=O)O)=CC=C1C1=CC=C(C(O)=O)S1 DDFHBQSCUXNBSA-UHFFFAOYSA-N 0.000 description 1
- KXKOMABBABBLKI-UHFFFAOYSA-N 5-amino-3-benzylidene-1,4,7,7-tetramethylbicyclo[2.2.1]heptan-2-one Chemical compound NC1C2(C(C(C(C1)(C2(C)C)C)=O)=CC2=CC=CC=C2)C KXKOMABBABBLKI-UHFFFAOYSA-N 0.000 description 1
- GJCOSYZMQJWQCA-UHFFFAOYSA-N 9H-xanthene Chemical compound C1=CC=C2CC3=CC=CC=C3OC2=C1 GJCOSYZMQJWQCA-UHFFFAOYSA-N 0.000 description 1
- 235000007173 Abies balsamea Nutrition 0.000 description 1
- 241001116389 Aloe Species 0.000 description 1
- 244000144730 Amygdalus persica Species 0.000 description 1
- 241000086254 Arnica montana Species 0.000 description 1
- 241000228245 Aspergillus niger Species 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 239000004857 Balsam Substances 0.000 description 1
- 239000004342 Benzoyl peroxide Substances 0.000 description 1
- OMPJBNCRMGITSC-UHFFFAOYSA-N Benzoylperoxide Chemical compound C=1C=CC=CC=1C(=O)OOC(=O)C1=CC=CC=C1 OMPJBNCRMGITSC-UHFFFAOYSA-N 0.000 description 1
- 239000002028 Biomass Substances 0.000 description 1
- LSNNMFCWUKXFEE-UHFFFAOYSA-M Bisulfite Chemical compound OS([O-])=O LSNNMFCWUKXFEE-UHFFFAOYSA-M 0.000 description 1
- 241000195940 Bryophyta Species 0.000 description 1
- 239000004322 Butylated hydroxytoluene Substances 0.000 description 1
- NLZUEZXRPGMBCV-UHFFFAOYSA-N Butylhydroxytoluene Chemical compound CC1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1 NLZUEZXRPGMBCV-UHFFFAOYSA-N 0.000 description 1
- QFOHBWFCKVYLES-UHFFFAOYSA-N Butylparaben Chemical compound CCCCOC(=O)C1=CC=C(O)C=C1 QFOHBWFCKVYLES-UHFFFAOYSA-N 0.000 description 1
- 241000208197 Buxus Species 0.000 description 1
- IEMRANFRGCVRQI-UHFFFAOYSA-N CC(C(C)C)OC(C=CC1=CC=C(C=C1)OCC)=O Chemical compound CC(C(C)C)OC(C=CC1=CC=C(C=C1)OCC)=O IEMRANFRGCVRQI-UHFFFAOYSA-N 0.000 description 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- GHOKWGTUZJEAQD-UHFFFAOYSA-N Chick antidermatitis factor Natural products OCC(C)(C)C(O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-UHFFFAOYSA-N 0.000 description 1
- WBYWAXJHAXSJNI-SREVYHEPSA-N Cinnamic acid Chemical compound OC(=O)\C=C/C1=CC=CC=C1 WBYWAXJHAXSJNI-SREVYHEPSA-N 0.000 description 1
- 102000008186 Collagen Human genes 0.000 description 1
- 108010035532 Collagen Proteins 0.000 description 1
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 1
- 241000195493 Cryptophyta Species 0.000 description 1
- 229920001651 Cyanoacrylate Polymers 0.000 description 1
- 241000235646 Cyberlindnera jadinii Species 0.000 description 1
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 description 1
- SNPLKNRPJHDVJA-ZETCQYMHSA-N D-panthenol Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCCO SNPLKNRPJHDVJA-ZETCQYMHSA-N 0.000 description 1
- 235000004866 D-panthenol Nutrition 0.000 description 1
- 208000002064 Dental Plaque Diseases 0.000 description 1
- 239000000253 Denture Cleanser Substances 0.000 description 1
- RWSOTUBLDIXVET-UHFFFAOYSA-N Dihydrogen sulfide Chemical compound S RWSOTUBLDIXVET-UHFFFAOYSA-N 0.000 description 1
- 102000016942 Elastin Human genes 0.000 description 1
- 108010014258 Elastin Proteins 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- BRLQWZUYTZBJKN-UHFFFAOYSA-N Epichlorohydrin Chemical compound ClCC1CO1 BRLQWZUYTZBJKN-UHFFFAOYSA-N 0.000 description 1
- 241000758993 Equisetidae Species 0.000 description 1
- 239000005977 Ethylene Substances 0.000 description 1
- FMRHJJZUHUTGKE-UHFFFAOYSA-N Ethylhexyl salicylate Chemical compound CCCCC(CC)COC(=O)C1=CC=CC=C1O FMRHJJZUHUTGKE-UHFFFAOYSA-N 0.000 description 1
- KRHYYFGTRYWZRS-UHFFFAOYSA-M Fluoride anion Chemical compound [F-] KRHYYFGTRYWZRS-UHFFFAOYSA-M 0.000 description 1
- HSRJKNPTNIJEKV-UHFFFAOYSA-N Guaifenesin Chemical compound COC1=CC=CC=C1OCC(O)CO HSRJKNPTNIJEKV-UHFFFAOYSA-N 0.000 description 1
- PNENOUKIPPERMY-UHFFFAOYSA-N HC Yellow No. 4 Chemical compound OCCNC1=CC=C([N+]([O-])=O)C=C1OCCO PNENOUKIPPERMY-UHFFFAOYSA-N 0.000 description 1
- 235000019487 Hazelnut oil Nutrition 0.000 description 1
- 206010020649 Hyperkeratosis Diseases 0.000 description 1
- 244000018716 Impatiens biflora Species 0.000 description 1
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 1
- XETQTCAMTVHYPO-UHFFFAOYSA-N Isocamphan von ungewisser Konfiguration Natural products C1CC2C(C)(C)C(C)C1C2 XETQTCAMTVHYPO-UHFFFAOYSA-N 0.000 description 1
- 241001446187 Kermes Species 0.000 description 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 1
- 241001508687 Mustela erminea Species 0.000 description 1
- MMOXZBCLCQITDF-UHFFFAOYSA-N N,N-diethyl-m-toluamide Chemical group CCN(CC)C(=O)C1=CC=CC(C)=C1 MMOXZBCLCQITDF-UHFFFAOYSA-N 0.000 description 1
- YBGZDTIWKVFICR-JLHYYAGUSA-N Octyl 4-methoxycinnamic acid Chemical compound CCCCC(CC)COC(=O)\C=C\C1=CC=C(OC)C=C1 YBGZDTIWKVFICR-JLHYYAGUSA-N 0.000 description 1
- 240000007594 Oryza sativa Species 0.000 description 1
- 235000007164 Oryza sativa Nutrition 0.000 description 1
- 240000004371 Panax ginseng Species 0.000 description 1
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 description 1
- 235000003140 Panax quinquefolius Nutrition 0.000 description 1
- 239000005662 Paraffin oil Substances 0.000 description 1
- 241000218196 Persea Species 0.000 description 1
- 235000008673 Persea americana Nutrition 0.000 description 1
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 1
- 240000006711 Pistacia vera Species 0.000 description 1
- 235000003447 Pistacia vera Nutrition 0.000 description 1
- RVGRUAULSDPKGF-UHFFFAOYSA-N Poloxamer Chemical compound C1CO1.CC1CO1 RVGRUAULSDPKGF-UHFFFAOYSA-N 0.000 description 1
- 239000002202 Polyethylene glycol Substances 0.000 description 1
- 239000004372 Polyvinyl alcohol Substances 0.000 description 1
- OFOBLEOULBTSOW-UHFFFAOYSA-N Propanedioic acid Natural products OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 description 1
- 241000241413 Propolis Species 0.000 description 1
- 235000006040 Prunus persica var persica Nutrition 0.000 description 1
- 241000235070 Saccharomyces Species 0.000 description 1
- 244000253911 Saccharomyces fragilis Species 0.000 description 1
- 235000018368 Saccharomyces fragilis Nutrition 0.000 description 1
- 235000019485 Safflower oil Nutrition 0.000 description 1
- 241000277331 Salmonidae Species 0.000 description 1
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 1
- 206010040829 Skin discolouration Diseases 0.000 description 1
- RCTGMCJBQGBLKT-UHFFFAOYSA-N Sudan IV Chemical compound CC1=CC=CC=C1N=NC(C=C1C)=CC=C1N=NC1=C(O)C=CC2=CC=CC=C12 RCTGMCJBQGBLKT-UHFFFAOYSA-N 0.000 description 1
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 1
- 206010042496 Sunburn Diseases 0.000 description 1
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 description 1
- DOOTYTYQINUNNV-UHFFFAOYSA-N Triethyl citrate Chemical compound CCOC(=O)CC(O)(C(=O)OCC)CC(=O)OCC DOOTYTYQINUNNV-UHFFFAOYSA-N 0.000 description 1
- 244000274883 Urtica dioica Species 0.000 description 1
- 235000009108 Urtica dioica Nutrition 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 1
- NBGWWMTXJHLJIM-UHFFFAOYSA-M [3-[[4-[(3,4-diamino-2-phenyldiazenylphenyl)diazenyl]naphthalen-1-yl]diazenyl]phenyl]-trimethylazanium;chloride Chemical compound [Cl-].C[N+](C)(C)C1=CC=CC(N=NC=2C3=CC=CC=C3C(N=NC=3C(=C(N)C(N)=CC=3)N=NC=3C=CC=CC=3)=CC=2)=C1 NBGWWMTXJHLJIM-UHFFFAOYSA-M 0.000 description 1
- 239000006096 absorbing agent Substances 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 239000011149 active material Substances 0.000 description 1
- 239000012042 active reagent Substances 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 235000010443 alginic acid Nutrition 0.000 description 1
- 239000000783 alginic acid Substances 0.000 description 1
- 229920000615 alginic acid Polymers 0.000 description 1
- 229960001126 alginic acid Drugs 0.000 description 1
- 150000004781 alginic acids Chemical class 0.000 description 1
- 150000001349 alkyl fluorides Chemical class 0.000 description 1
- SHGAZHPCJJPHSC-YCNIQYBTSA-N all-trans-retinoic acid Chemical compound OC(=O)\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C SHGAZHPCJJPHSC-YCNIQYBTSA-N 0.000 description 1
- AZDRQVAHHNSJOQ-UHFFFAOYSA-N alumane Chemical class [AlH3] AZDRQVAHHNSJOQ-UHFFFAOYSA-N 0.000 description 1
- UBNYRXMKIIGMKK-RMKNXTFCSA-N amiloxate Chemical compound COC1=CC=C(\C=C\C(=O)OCCC(C)C)C=C1 UBNYRXMKIIGMKK-RMKNXTFCSA-N 0.000 description 1
- 229940024606 amino acid Drugs 0.000 description 1
- 229960004050 aminobenzoic acid Drugs 0.000 description 1
- QGZKDVFQNNGYKY-UHFFFAOYSA-O ammonium group Chemical class [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 description 1
- PYKYMHQGRFAEBM-UHFFFAOYSA-N anthraquinone Natural products CCC(=O)c1c(O)c2C(=O)C3C(C=CC=C3O)C(=O)c2cc1CC(=O)OC PYKYMHQGRFAEBM-UHFFFAOYSA-N 0.000 description 1
- 150000004056 anthraquinones Chemical class 0.000 description 1
- 230000002421 anti-septic effect Effects 0.000 description 1
- 239000008346 aqueous phase Substances 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 238000006701 autoxidation reaction Methods 0.000 description 1
- 239000010480 babassu oil Substances 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 238000003287 bathing Methods 0.000 description 1
- 150000001565 benzotriazoles Chemical class 0.000 description 1
- 235000019400 benzoyl peroxide Nutrition 0.000 description 1
- 235000020958 biotin Nutrition 0.000 description 1
- 239000011616 biotin Substances 0.000 description 1
- 229960002685 biotin Drugs 0.000 description 1
- YEAYGXLRPMKZBP-KQGICBIGSA-N bis(2-hydroxyethyl)azanium;(e)-3-(4-methoxyphenyl)prop-2-enoate Chemical class OCCNCCO.COC1=CC=C(\C=C\C(O)=O)C=C1 YEAYGXLRPMKZBP-KQGICBIGSA-N 0.000 description 1
- 239000010473 blackcurrant seed oil Substances 0.000 description 1
- 239000007844 bleaching agent Substances 0.000 description 1
- 235000021324 borage oil Nutrition 0.000 description 1
- 239000010474 borage seed oil Substances 0.000 description 1
- 229930006742 bornane Natural products 0.000 description 1
- 238000005282 brightening Methods 0.000 description 1
- 125000000484 butyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 235000010354 butylated hydroxytoluene Nutrition 0.000 description 1
- 229940095259 butylated hydroxytoluene Drugs 0.000 description 1
- 235000004883 caffeic acid Nutrition 0.000 description 1
- 229940074360 caffeic acid Drugs 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 239000010238 camphora Substances 0.000 description 1
- 229940025250 camphora Drugs 0.000 description 1
- 239000004202 carbamide Substances 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 235000021466 carotenoid Nutrition 0.000 description 1
- 150000001747 carotenoids Chemical class 0.000 description 1
- 238000005266 casting Methods 0.000 description 1
- 125000002091 cationic group Chemical group 0.000 description 1
- 229920003086 cellulose ether Polymers 0.000 description 1
- 239000004568 cement Substances 0.000 description 1
- 235000013339 cereals Nutrition 0.000 description 1
- OIQPTROHQCGFEF-UHFFFAOYSA-L chembl1371409 Chemical compound [Na+].[Na+].OC1=CC=C2C=C(S([O-])(=O)=O)C=CC2=C1N=NC1=CC=C(S([O-])(=O)=O)C=C1 OIQPTROHQCGFEF-UHFFFAOYSA-L 0.000 description 1
- ONTQJDKFANPPKK-UHFFFAOYSA-L chembl3185981 Chemical compound [Na+].[Na+].CC1=CC(C)=C(S([O-])(=O)=O)C=C1N=NC1=CC(S([O-])(=O)=O)=C(C=CC=C2)C2=C1O ONTQJDKFANPPKK-UHFFFAOYSA-L 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 239000013626 chemical specie Substances 0.000 description 1
- APEJMQOBVMLION-UHFFFAOYSA-N cinnamamide Chemical class NC(=O)C=CC1=CC=CC=C1 APEJMQOBVMLION-UHFFFAOYSA-N 0.000 description 1
- 229940114081 cinnamate Drugs 0.000 description 1
- 235000013985 cinnamic acid Nutrition 0.000 description 1
- 229930016911 cinnamic acid Natural products 0.000 description 1
- 150000001851 cinnamic acid derivatives Chemical class 0.000 description 1
- QAIPRVGONGVQAS-UHFFFAOYSA-N cis-caffeic acid Natural products OC(=O)C=CC1=CC=C(O)C(O)=C1 QAIPRVGONGVQAS-UHFFFAOYSA-N 0.000 description 1
- FDJOLVPMNUYSCM-UVKKECPRSA-L cobalt(3+);[(2r,3s,4r,5s)-5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [(2r)-1-[3-[(2r,3r,4z,7s,9z,12s,13s,14z,17s,18s,19r)-2,13,18-tris(2-amino-2-oxoethyl)-7,12,17-tris(3-amino-3-oxopropyl)-3,5,8,8,13,15,18,19-octamethyl-2,7, Chemical compound [Co+3].N#[C-].C1([C@H](CC(N)=O)[C@@]2(C)CCC(=O)NC[C@@H](C)OP([O-])(=O)O[C@H]3[C@H]([C@H](O[C@@H]3CO)N3C4=CC(C)=C(C)C=C4N=C3)O)[N-]\C2=C(C)/C([C@H](C\2(C)C)CCC(N)=O)=N/C/2=C\C([C@H]([C@@]/2(CC(N)=O)C)CCC(N)=O)=N\C\2=C(C)/C2=N[C@]1(C)[C@@](C)(CC(N)=O)[C@@H]2CCC(N)=O FDJOLVPMNUYSCM-UVKKECPRSA-L 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 229910052802 copper Inorganic materials 0.000 description 1
- 239000010949 copper Substances 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 230000018044 dehydration Effects 0.000 description 1
- 238000006297 dehydration reaction Methods 0.000 description 1
- 210000003298 dental enamel Anatomy 0.000 description 1
- 230000001877 deodorizing effect Effects 0.000 description 1
- 239000007854 depigmenting agent Substances 0.000 description 1
- 239000003599 detergent Substances 0.000 description 1
- ZBCBWPMODOFKDW-UHFFFAOYSA-N diethanolamine Chemical class OCCNCCO ZBCBWPMODOFKDW-UHFFFAOYSA-N 0.000 description 1
- ZOMNIUBKTOKEHS-UHFFFAOYSA-L dimercury dichloride Chemical group Cl[Hg][Hg]Cl ZOMNIUBKTOKEHS-UHFFFAOYSA-L 0.000 description 1
- JMGZBMRVDHKMKB-UHFFFAOYSA-L disodium;2-sulfobutanedioate Chemical compound [Na+].[Na+].OS(=O)(=O)C(C([O-])=O)CC([O-])=O JMGZBMRVDHKMKB-UHFFFAOYSA-L 0.000 description 1
- 239000002270 dispersing agent Substances 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 125000003438 dodecyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 230000002500 effect on skin Effects 0.000 description 1
- 229920002549 elastin Polymers 0.000 description 1
- UVCJGUGAGLDPAA-UHFFFAOYSA-N ensulizole Chemical compound N1C2=CC(S(=O)(=O)O)=CC=C2N=C1C1=CC=CC=C1 UVCJGUGAGLDPAA-UHFFFAOYSA-N 0.000 description 1
- 229960000655 ensulizole Drugs 0.000 description 1
- 229960004697 enzacamene Drugs 0.000 description 1
- 235000012732 erythrosine Nutrition 0.000 description 1
- 235000004626 essential fatty acids Nutrition 0.000 description 1
- 235000019441 ethanol Nutrition 0.000 description 1
- IAJNXBNRYMEYAZ-UHFFFAOYSA-N ethyl 2-cyano-3,3-diphenylprop-2-enoate Chemical group C=1C=CC=CC=1C(=C(C#N)C(=O)OCC)C1=CC=CC=C1 IAJNXBNRYMEYAZ-UHFFFAOYSA-N 0.000 description 1
- TVQGDYNRXLTQAP-UHFFFAOYSA-N ethyl heptanoate Chemical compound CCCCCCC(=O)OCC TVQGDYNRXLTQAP-UHFFFAOYSA-N 0.000 description 1
- 229940068171 ethyl hexyl salicylate Drugs 0.000 description 1
- SFNALCNOMXIBKG-UHFFFAOYSA-N ethylene glycol monododecyl ether Chemical compound CCCCCCCCCCCCOCCO SFNALCNOMXIBKG-UHFFFAOYSA-N 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- 230000008020 evaporation Effects 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 230000009969 flowable effect Effects 0.000 description 1
- 238000005187 foaming Methods 0.000 description 1
- 239000004088 foaming agent Substances 0.000 description 1
- 235000013373 food additive Nutrition 0.000 description 1
- 239000002778 food additive Substances 0.000 description 1
- 238000004108 freeze drying Methods 0.000 description 1
- FODTZLFLDFKIQH-FSVGXZBPSA-N gamma-Oryzanol (TN) Chemical compound C1=C(O)C(OC)=CC(\C=C\C(=O)O[C@@H]2C([C@@H]3CC[C@H]4[C@]5(C)CC[C@@H]([C@@]5(C)CC[C@@]54C[C@@]53CC2)[C@H](C)CCC=C(C)C)(C)C)=C1 FODTZLFLDFKIQH-FSVGXZBPSA-N 0.000 description 1
- 235000008434 ginseng Nutrition 0.000 description 1
- 238000000227 grinding Methods 0.000 description 1
- 238000009499 grossing Methods 0.000 description 1
- 239000001963 growth medium Substances 0.000 description 1
- 239000008266 hair spray Substances 0.000 description 1
- 230000003699 hair surface Effects 0.000 description 1
- 239000010468 hazelnut oil Substances 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 239000010460 hemp oil Substances 0.000 description 1
- ACGUYXCXAPNIKK-UHFFFAOYSA-N hexachlorophene Chemical compound OC1=C(Cl)C=C(Cl)C(Cl)=C1CC1=C(O)C(Cl)=CC(Cl)=C1Cl ACGUYXCXAPNIKK-UHFFFAOYSA-N 0.000 description 1
- 229960004068 hexachlorophene Drugs 0.000 description 1
- 229920002674 hyaluronan Polymers 0.000 description 1
- 229960003160 hyaluronic acid Drugs 0.000 description 1
- 239000000017 hydrogel Substances 0.000 description 1
- 229960002163 hydrogen peroxide Drugs 0.000 description 1
- RERASOSSWQIKNJ-UHFFFAOYSA-N imidazolidin-4-ylurea Chemical compound NC(=O)NC1CNCN1 RERASOSSWQIKNJ-UHFFFAOYSA-N 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 230000002779 inactivation Effects 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 239000008384 inner phase Substances 0.000 description 1
- 239000002917 insecticide Substances 0.000 description 1
- 239000003456 ion exchange resin Substances 0.000 description 1
- 229920003303 ion-exchange polymer Polymers 0.000 description 1
- XUGNVMKQXJXZCD-UHFFFAOYSA-N isopropyl palmitate Chemical compound CCCCCCCCCCCCCCCC(=O)OC(C)C XUGNVMKQXJXZCD-UHFFFAOYSA-N 0.000 description 1
- CXORMDKZEUMQHX-UHFFFAOYSA-N kermesic acid Chemical compound O=C1C2=C(O)C(O)=CC(O)=C2C(=O)C2=C1C=C(O)C(C(O)=O)=C2C CXORMDKZEUMQHX-UHFFFAOYSA-N 0.000 description 1
- 235000014655 lactic acid Nutrition 0.000 description 1
- 239000004310 lactic acid Substances 0.000 description 1
- QDLAGTHXVHQKRE-UHFFFAOYSA-N lichenxanthone Natural products COC1=CC(O)=C2C(=O)C3=C(C)C=C(OC)C=C3OC2=C1 QDLAGTHXVHQKRE-UHFFFAOYSA-N 0.000 description 1
- 239000011344 liquid material Substances 0.000 description 1
- 239000006210 lotion Substances 0.000 description 1
- 239000000314 lubricant Substances 0.000 description 1
- 239000011777 magnesium Substances 0.000 description 1
- 229910052749 magnesium Inorganic materials 0.000 description 1
- CSNNHWWHGAXBCP-UHFFFAOYSA-L magnesium sulphate Substances [Mg+2].[O-][S+2]([O-])([O-])[O-] CSNNHWWHGAXBCP-UHFFFAOYSA-L 0.000 description 1
- 235000019341 magnesium sulphate Nutrition 0.000 description 1
- WPBNNNQJVZRUHP-UHFFFAOYSA-L manganese(2+);methyl n-[[2-(methoxycarbonylcarbamothioylamino)phenyl]carbamothioyl]carbamate;n-[2-(sulfidocarbothioylamino)ethyl]carbamodithioate Chemical compound [Mn+2].[S-]C(=S)NCCNC([S-])=S.COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC WPBNNNQJVZRUHP-UHFFFAOYSA-L 0.000 description 1
- 239000002609 medium Substances 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 229940098779 methanesulfonic acid Drugs 0.000 description 1
- AFVFQIVMOAPDHO-UHFFFAOYSA-N methanesulfonic acid Substances CS(O)(=O)=O AFVFQIVMOAPDHO-UHFFFAOYSA-N 0.000 description 1
- 125000001434 methanylylidene group Chemical group [H]C#[*] 0.000 description 1
- CJCPHVRHJKYIJC-UHFFFAOYSA-N methyl 2-hydroxybenzoate;sodium Chemical class [Na].COC(=O)C1=CC=CC=C1O CJCPHVRHJKYIJC-UHFFFAOYSA-N 0.000 description 1
- WBYWAXJHAXSJNI-UHFFFAOYSA-N methyl p-hydroxycinnamate Natural products OC(=O)C=CC1=CC=CC=C1 WBYWAXJHAXSJNI-UHFFFAOYSA-N 0.000 description 1
- 235000013336 milk Nutrition 0.000 description 1
- 239000008267 milk Substances 0.000 description 1
- 210000004080 milk Anatomy 0.000 description 1
- 235000011929 mousse Nutrition 0.000 description 1
- 210000000282 nail Anatomy 0.000 description 1
- 239000001005 nitro dye Substances 0.000 description 1
- LQNUZADURLCDLV-UHFFFAOYSA-N nitrobenzene Chemical compound [O-][N+](=O)C1=CC=CC=C1 LQNUZADURLCDLV-UHFFFAOYSA-N 0.000 description 1
- 231100001143 noxa Toxicity 0.000 description 1
- 235000019488 nut oil Nutrition 0.000 description 1
- CXQXSVUQTKDNFP-UHFFFAOYSA-N octamethyltrisiloxane Chemical class C[Si](C)(C)O[Si](C)(C)O[Si](C)(C)C CXQXSVUQTKDNFP-UHFFFAOYSA-N 0.000 description 1
- WQDGUYZIAJKLAB-UHFFFAOYSA-N octan-2-yl nitrite Chemical compound CCCCCCC(C)ON=O WQDGUYZIAJKLAB-UHFFFAOYSA-N 0.000 description 1
- WWZKQHOCKIZLMA-UHFFFAOYSA-N octanoic acid Chemical compound CCCCCCCC(O)=O WWZKQHOCKIZLMA-UHFFFAOYSA-N 0.000 description 1
- 229960001679 octinoxate Drugs 0.000 description 1
- FMJSMJQBSVNSBF-UHFFFAOYSA-N octocrylene Chemical group C=1C=CC=CC=1C(=C(C#N)C(=O)OCC(CC)CCCC)C1=CC=CC=C1 FMJSMJQBSVNSBF-UHFFFAOYSA-N 0.000 description 1
- 229960000601 octocrylene Drugs 0.000 description 1
- VIKVSUVYUVJHOA-UHFFFAOYSA-N octyl 3-phenylprop-2-enoate Chemical compound CCCCCCCCOC(=O)C=CC1=CC=CC=C1 VIKVSUVYUVJHOA-UHFFFAOYSA-N 0.000 description 1
- 125000002347 octyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 239000002674 ointment Substances 0.000 description 1
- 229960001245 olaflur Drugs 0.000 description 1
- 239000004006 olive oil Substances 0.000 description 1
- 235000008390 olive oil Nutrition 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 229940055726 pantothenic acid Drugs 0.000 description 1
- 235000019161 pantothenic acid Nutrition 0.000 description 1
- 239000011713 pantothenic acid Substances 0.000 description 1
- QQVIHTHCMHWDBS-UHFFFAOYSA-N perisophthalic acid Natural products OC(=O)C1=CC=CC(C(O)=O)=C1 QQVIHTHCMHWDBS-UHFFFAOYSA-N 0.000 description 1
- 229960005323 phenoxyethanol Drugs 0.000 description 1
- 229910052698 phosphorus Inorganic materials 0.000 description 1
- 239000011574 phosphorus Substances 0.000 description 1
- IEQIEDJGQAUEQZ-UHFFFAOYSA-N phthalocyanine Chemical compound N1C(N=C2C3=CC=CC=C3C(N=C3C4=CC=CC=C4C(=N4)N3)=N2)=C(C=CC=C2)C2=C1N=C1C2=CC=CC=C2C4=N1 IEQIEDJGQAUEQZ-UHFFFAOYSA-N 0.000 description 1
- 210000002826 placenta Anatomy 0.000 description 1
- 229960000502 poloxamer Drugs 0.000 description 1
- 229920000058 polyacrylate Polymers 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 238000006116 polymerization reaction Methods 0.000 description 1
- 229920002451 polyvinyl alcohol Polymers 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 238000003672 processing method Methods 0.000 description 1
- 239000003380 propellant Substances 0.000 description 1
- 229940069949 propolis Drugs 0.000 description 1
- 239000004405 propyl p-hydroxybenzoate Substances 0.000 description 1
- 235000013772 propylene glycol Nutrition 0.000 description 1
- 229960003415 propylparaben Drugs 0.000 description 1
- 235000018102 proteins Nutrition 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 238000005086 pumping Methods 0.000 description 1
- 150000003856 quaternary ammonium compounds Chemical class 0.000 description 1
- 150000003242 quaternary ammonium salts Chemical class 0.000 description 1
- TVRGPOFMYCMNRB-UHFFFAOYSA-N quinizarine green ss Chemical compound C1=CC(C)=CC=C1NC(C=1C(=O)C2=CC=CC=C2C(=O)C=11)=CC=C1NC1=CC=C(C)C=C1 TVRGPOFMYCMNRB-UHFFFAOYSA-N 0.000 description 1
- 239000002516 radical scavenger Substances 0.000 description 1
- 238000009418 renovation Methods 0.000 description 1
- 235000009566 rice Nutrition 0.000 description 1
- WBHHMMIMDMUBKC-XLNAKTSKSA-N ricinelaidic acid Chemical compound CCCCCC[C@@H](O)C\C=C\CCCCCCCC(O)=O WBHHMMIMDMUBKC-XLNAKTSKSA-N 0.000 description 1
- 229960003656 ricinoleic acid Drugs 0.000 description 1
- FEUQNCSVHBHROZ-UHFFFAOYSA-N ricinoleic acid Natural products CCCCCCC(O[Si](C)(C)C)CC=CCCCCCCCC(=O)OC FEUQNCSVHBHROZ-UHFFFAOYSA-N 0.000 description 1
- 229940085605 saccharin sodium Drugs 0.000 description 1
- 239000003813 safflower oil Substances 0.000 description 1
- 235000005713 safflower oil Nutrition 0.000 description 1
- RCTGMCJBQGBLKT-PAMTUDGESA-N scarlet red Chemical compound CC1=CC=CC=C1\N=N\C(C=C1C)=CC=C1\N=N\C1=C(O)C=CC2=CC=CC=C12 RCTGMCJBQGBLKT-PAMTUDGESA-N 0.000 description 1
- 239000010703 silicon Substances 0.000 description 1
- 229910052710 silicon Inorganic materials 0.000 description 1
- 239000002002 slurry Substances 0.000 description 1
- 239000000661 sodium alginate Substances 0.000 description 1
- 235000010413 sodium alginate Nutrition 0.000 description 1
- 229940005550 sodium alginate Drugs 0.000 description 1
- WXMKPNITSTVMEF-UHFFFAOYSA-M sodium benzoate Chemical compound [Na+].[O-]C(=O)C1=CC=CC=C1 WXMKPNITSTVMEF-UHFFFAOYSA-M 0.000 description 1
- 235000010234 sodium benzoate Nutrition 0.000 description 1
- 239000004299 sodium benzoate Substances 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 239000001540 sodium lactate Substances 0.000 description 1
- 235000011088 sodium lactate Nutrition 0.000 description 1
- 229940005581 sodium lactate Drugs 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 201000004647 tinea pedis Diseases 0.000 description 1
- 239000011573 trace mineral Substances 0.000 description 1
- 235000013619 trace mineral Nutrition 0.000 description 1
- 230000032258 transport Effects 0.000 description 1
- 229960001727 tretinoin Drugs 0.000 description 1
- LADGBHLMCUINGV-UHFFFAOYSA-N tricaprin Chemical compound CCCCCCCCCC(=O)OCC(OC(=O)CCCCCCCCC)COC(=O)CCCCCCCCC LADGBHLMCUINGV-UHFFFAOYSA-N 0.000 description 1
- 239000001069 triethyl citrate Substances 0.000 description 1
- VMYFZRTXGLUXMZ-UHFFFAOYSA-N triethyl citrate Natural products CCOC(=O)C(O)(C(=O)OCC)C(=O)OCC VMYFZRTXGLUXMZ-UHFFFAOYSA-N 0.000 description 1
- 235000013769 triethyl citrate Nutrition 0.000 description 1
- XFNJVJPLKCPIBV-UHFFFAOYSA-N trimethylenediamine Natural products NCCCN XFNJVJPLKCPIBV-UHFFFAOYSA-N 0.000 description 1
- UJMBCXLDXJUMFB-UHFFFAOYSA-K trisodium;5-oxo-1-(4-sulfonatophenyl)-4-[(4-sulfonatophenyl)diazenyl]-4h-pyrazole-3-carboxylate Chemical compound [Na+].[Na+].[Na+].[O-]C(=O)C1=NN(C=2C=CC(=CC=2)S([O-])(=O)=O)C(=O)C1N=NC1=CC=C(S([O-])(=O)=O)C=C1 UJMBCXLDXJUMFB-UHFFFAOYSA-K 0.000 description 1
- 229960004418 trolamine Drugs 0.000 description 1
- UEVAMYPIMMOEFW-UHFFFAOYSA-N trolamine salicylate Chemical class OCCN(CCO)CCO.OC(=O)C1=CC=CC=C1O UEVAMYPIMMOEFW-UHFFFAOYSA-N 0.000 description 1
- 239000000341 volatile oil Substances 0.000 description 1
- 239000010497 wheat germ oil Substances 0.000 description 1
- 239000002023 wood Substances 0.000 description 1
- 239000000230 xanthan gum Substances 0.000 description 1
- 229920001285 xanthan gum Polymers 0.000 description 1
- 235000010493 xanthan gum Nutrition 0.000 description 1
- 229940082509 xanthan gum Drugs 0.000 description 1
- 150000003751 zinc Chemical class 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/046—Aerosols; Foams
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/11—Encapsulated compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/347—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/676—Ascorbic acid, i.e. vitamin C
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/678—Tocopherol, i.e. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/69—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing fluorine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9728—Fungi, e.g. yeasts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9733—Lichens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
- A61Q1/02—Preparations containing skin colorants, e.g. pigments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q13/00—Formulations or additives for perfume preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q15/00—Anti-perspirants or body deodorants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/02—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings containing insect repellants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/002—Aftershave preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/004—Aftersun preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/04—Preparations for care of the skin for chemically tanning the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q3/00—Manicure or pedicure preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/02—Preparations for cleaning the hair
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q9/00—Preparations for removing hair or for aiding hair removal
- A61Q9/02—Shaving preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/41—Particular ingredients further characterized by their size
- A61K2800/412—Microsized, i.e. having sizes between 0.1 and 100 microns
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9706—Algae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/99—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Dermatology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dispersion Chemistry (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Emergency Medicine (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Cosmetics (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
描述了微生物包封材料(填充的生物胶囊),特别是酵母在化妆品最终配方中的应用。
Description
本发明涉及微生物包封的材料在化妆品最终配方中的应用,也涉及含有这些生物胶囊的化妆品最终配方,以及这些最终配方的各种用途。
已知可在微胶囊中包封入各种活性组分,微胶囊是天然的,或者换句话说,可以称其为生物胶囊。
EP-A-0,242,135描述了包封的常规方法,特别描述了酵母胶囊。
WO 94/22572公开了一种生物胶囊的改进制备方法,以及其优选的用途,例如作食品添加剂。
令人吃惊地是,现已发现,微生物包封的化妆品活性组分能够以很简单的方式加入化妆品最终配方,同时保持它们的形态和物理化学性质。
因此,本发明提供了微生物包封的材料在化妆品最终配方中的应用。本发明的应用值得注意的地方在于微生物包封的材料含有一种或多种液体或可微生物包封化妆品活性组分。
用于包封的微生物材料优选是真菌。典型实例是酵母,例如酿酒酵母(啤酒酵母以及发面酵母),克卢费氏酵母属fragilis(乳品酵母),以及产朊假丝酵母,以及纤维状的真菌,例如黑曲霉。
可用于本发明的其它微生物材料是细菌和藻类。
根据本发明,优选使用酵母作为所述微生物材料。
根据本发明,微生物材料是完全成熟的形式,即已经从其培养基采集下来,并且是完整的。微生物材料优选是活的,至少在化妆品活性组分开始加入时是活的。
微生物材料优选的细胞直径是约5μm。细菌可以具有更小的细胞大小,为约1-2μm,并且可将其培养得到相对更大的细胞直径。
对于本发明,不需要微生物材料具有某些脂类内容物。一般地,脂类内容物不超过微生物干重的5%,优选最高达3%。
待包封的材料,即化妆品活性组分,应该在加工的整个过程中处于液态。这里,所述材料本身可以是液体(包括油),或者其也可能使用溶解或微分散在适当溶剂或分散剂中的固体。就此而论,重要的是选择溶剂,使其也不可与微生物材料混溶。适合的溶剂的例子是低级醇,例如甲醇,乙醇或异丙醇。如果希望,可以在包封加工之后将溶剂通过例如喷雾干燥来除去。
待包封的材料不能溶于微生物材料的任何形成脂的部分,并且不应引起微生物细胞壁的撕裂。
适合的可包封的材料是适用于皮肤化妆品的活性组分、活性组分组合物或活性组分萃取物、适合皮肤施用或局部施用的一种组分或多种组分的混合物。举例来说,可以列举如下物质:
-对皮肤和头发表面具有清洁以及护理作用的活性组分。这些包括用于皮肤清洁的全部物质,如油类、皂类、合成洗涤剂以及固态物质;
-具有除臭、止汗以及控制足癣作用的活性组分,特别是在运动卫生保健领域中的活性组分:这些包括基于铝盐或锌盐的止汗药,含有杀菌或抑菌除臭物质的除臭药,例如三氯生、六氯酚,醇类以及阳离子活化物质,例如季铵盐和气味吸收剂,例如Grillocin(蓖麻酸锌和各种添加剂的复合物)或柠檬酸三乙酯,任选与抗氧化剂例如丁基羟基甲苯相结合,或与离子交换树脂相结合;
-用于牙齿、假牙和口腔护理的活性组分,其存在于,例如牙膏、牙膏凝胶剂、牙粉、嗽口水浓缩液、抗牙斑漱口剂、假牙清洁剂或假牙粘合剂,例如脂族的氟化铵,特别是硬脂基三羟乙基亚丙基二胺二氢氟化物;
-提供防晒作用的活性组分(UV过滤剂):适合的活性组分是滤光物质(“防晒剂”),它能够从日光中吸收紫外线辐射并且将其转换为热。根据所希望的作用,优选以下光保护剂:有选择地吸收约280-315nm范围内会产生晒伤的高能量紫外线辐射并且透过约315-400nm的较长波(UV-A区)的光保护剂(UV-B吸收剂),以及只吸收315-400nm UV-A区的较长波辐射的光保护剂(UV-A吸收剂)。
适合的光保护剂是,例如有机紫外线吸收剂,其来自对氨基苯甲酸衍生物、水杨酸衍生物、二苯甲酮衍生物、二苯甲酰甲烷衍生物、二苯基丙烯酸酯衍生物、苯并呋喃衍生物;聚合紫外线吸收剂,其含有一种或多种有机硅基、肉桂酸衍生物、樟脑衍生物、三苯胺基-s-三嗪衍生物、间苯二酚基三嗪、苯基苯并咪唑磺酸及其盐、邻氨基苯甲酸薄荷酯和苯并三唑衍生物。对氨基苯甲酸衍生物的示范性化合物:4-氨基苯甲酸(PABA);具有下式的二羟丙基-PABA乙酯具有下式的二甲基-PABA辛酯或具有下式的氨基苯甲酸甘油酯水杨酸衍生物的示范性化合物:具有下式的水杨酸均薄荷酯具有下式的水杨酸三乙醇胺盐具有下式的对二甲氨基苯甲酸戊酯具有下式的水杨酸辛酯或具有下式的水杨酸4-异丙苄酯
二苯甲酮衍生物的示范性化合物:
二苯甲酮-3-(2-羟基-4-甲氧基二苯甲酮),二苯甲酮-4-(2-羟基-4-甲氧基二苯甲酮-5-磺酸)或二苯甲酮-8-(2,2′-二羟基-4-甲氧基二苯甲酮)。
二苯甲酰甲烷衍生物的示范性化合物:
丁基甲氧基二苯甲酰甲烷-[1-(4-叔丁基)-3-(4-甲氧基苯基)丙-1,3-二酮]。
二苯基丙烯酸酯衍生物的示范性化合物:
octocrylene(2-氰基-3,3′-二苯基丙烯酸2-乙基己酯)或etocrylene(2-氰基-3,3′-二苯基丙烯酸乙酯)。
苯并呋喃衍生物的示范性化合物:
2-氰基丙烯酸3-苯并呋喃酯,2-(2-苯并呋喃基)-5-叔丁基苯并噁唑或2-(对氨基苯基)苯并呋喃,特别是具有以下分子式的化合物或含有一种或多种有机硅基的聚合物UV吸收剂的示范性化合物:丙二酸亚苄基酯衍生物,特别是具有下式的化合物:其中R24是氢或O-Me,并且r是约7;具有下式的化合物或
肉桂酸酯的示范性化合物:
甲氧基肉桂酸辛酯(4-甲氧基肉桂酸2-乙基己酯),甲氧基肉桂酸二乙醇胺盐(4-甲氧基肉桂酸的二乙醇胺盐),对甲氧基肉桂酸异戊酯(4-乙氧基肉桂酸2-异戊基酯),肉桂酸2,5-二异丙基甲酯或肉桂酸酰氨衍生物。
樟脑衍生物的示范性化合物:
4-甲基亚苄基樟脑[3-(4′-甲基)亚苄基-莰-2-酮],3-亚苄基樟脑(3-亚苄基莰-2-酮),聚丙烯酰氨基甲基亚苄基樟脑{N-[2(和4)-2-氧亚莰-3-基-甲基)-苄基]-丙烯酰胺聚合物},三鎓亚苄基樟脑硫酸盐[3-(4′-三甲基铵)亚苄基莰-2-酮甲基硫酸盐],对苯二亚甲基二樟脑磺酸{3,3′-(1,4-亚苯基二次甲基)-双(7,7-二甲基-2-氧代-双环[2.2.1]庚烷-1-甲磺酸)}或其盐,或亚苄基樟脑磺酸[3-(4′-磺基)亚苄基-莰-2-酮]或其盐。
三苯胺基-2-三嗪衍生物的示范性化合物:
辛基三嗪[2,4,6-三苯胺-(对-碳-2’-乙基-1’-氧基)-1,3,5-三嗪],以及在US-A-5,332,568,US-A-5,252,323,WO 93/17002和WO97/03642以及EP-A-0,517,104中描述的三苯胺基-s-三嗪衍生物。
苯并三唑类化合物的示范性化合物:
2-(2-羟基-5-甲基苯基)苯并三唑;
在EP-A-0,746,305中描述的苯并三唑化合物,特别是具有下式的化合物
其中T2是氢或C1-C8烷基;
-防昆虫的活性组分(驱虫剂):驱虫剂是防止昆虫与皮肤接触并在皮肤上活动的试剂,它们赶走动物并且慢慢地蒸发。最经常使用的驱虫剂是二乙基甲苯甲酰胺(DEET)。W.Raab和U.Kindl的“Pflegekosmetik”[Care cosmetics],Gustav-Fischer-VerlagStuttgart/New York,1991,161页给出了其它常用的驱虫剂。
-用于防止化学和机械作用的活性组分:这些包括所有能在皮肤和外部害因之间形成屏障的物质,例如用于防护水溶液侵害的石蜡油、硅油、植物油、PCL产品和羊毛脂,用于防止有机溶剂伤害作用的成膜剂,如藻酸钠、藻酸三乙醇胺、聚丙烯酸酯、聚乙烯醇或纤维素醚,或作为“润滑剂”预防皮肤受到强机械应力作用的基于矿物油、植物油或硅油的物质。
-保湿剂物质:
例如,以下物质用作增湿调节剂(“补湿剂”):乳酸钠、脲、“天然增湿因子”(NMF)的氨基酸、醇类、山梨醇、甘油、丙二醇、胶原蛋白、弹性蛋白或透明质酸;
-具有角膜软化或溶角蛋白作用的活性组分:过氧化苯甲酰、视黄酸、胶态硫和间苯二酚,α-羟基羧酸,例如乳酸、水杨酸及其衍生物;
-抗微生物剂,例如卤化二苯醚化合物,特别是三氯生和二氯生,二苯醚,例如4-(2-叔丁基-5-甲基苯氧基)苯基或季铵化合物;
-含有游离基清除剂(抗氧化剂)或其亲脂性衍生物的试剂;
-可以在皮肤使用的油性或油溶性的维生素或维生素衍生物:例如维生素A(游离酸形式或其衍生物形式的视黄醇)、泛醇、泛酸、叶酸以及其复合物,维生素E(生育酚)、F;必需脂肪酸;或烟酰胺或其衍生物,亲油衍生的水溶性亲水性维生素;
-基于维生素的胎盘萃取物:主要含有维生素A、C、E和B12的活性组分组合物,叶酸和生物素,氨基酸和酵素,以及微量元素镁、硅、磷、钙、锰、铁或铜或其衍生物的化合物;
-用于漂白人的头发或用于淡化黑色素色斑(皮肤变白)的脱色剂:例如氢醌或其衍生物,抗坏血酸及衍生物和咖啡酸;
-皮肤晒褐剂:例如二羟丙酮(DHA)以及其变体,用于释放或吸收主要金属的络合剂或亲油衍生的络合剂;
-皮肤修复配合物:可以通过使Bifidus类型的细菌培养物失活并分解而得到;
-植物以及植物提取物:例如山菊油、芦荟、芒刺苔藓、常春藤、小荨麻、人参、指甲花、春黄菊、万寿菊、迷迭香、一串红、楔叶类植物或麝香草;
-动物提取物,例如蜂王浆、蜂胶、蛋白质或麝香草提取物;
-可以在皮肤使用的化妆用油类:Miglyol812型的中性油类,杏仁油、鳄梨油、巴巴苏仁油、棉籽油、琉璃苣籽油、大蓟油、花生油、γ谷维素、蔷薇果仁油、大麻籽油、榛子油、黑醋栗籽油、西蒙德木油、樱桃核油、鲑鱼油、亚麻油、玉米油、昆士兰果油、杏仁油、月见草油、貂油、橄榄油、山核桃仁油、桃仁油、阿月浑子果仁油、菜籽油、米粒油、蓖麻油、红花油、芝麻油、豆油、向日葵油、茶树油、葡萄籽油、麦胚油或蓝柏油。
可微生物包封的化妆品组分优选自可用于皮肤的香料和化妆用油类,优选自皮肤护理和皮肤清洁物质,优选自具有除臭以及止汗作用的活性组分,UV过滤剂,用于牙齿、假牙和口腔护理的活性组分,驱虫的活性组分,用于防化学和机械作用的活性组分,保湿剂物质,具有角膜软化作用的活性组分,抗微生物剂,可在皮肤上使用的油性或可溶于油的维生素或维生素衍生物,基于维生素的胎盘提取物,皮肤修复配合物,植物和植物提取物,动物提取物,染料,抗氧化剂,皮肤晒褐和皮肤增白物质,以及其它化妆品活性组分。
特别优选的可微生物包封的化妆品组分是抗微生物活性组分,其选自2-羟基-4,2′,4′-三氯二苯醚(三氯生),2-羟基-4,4′-二氯二苯醚(二氯生)或4-(2-叔丁基-5-甲基苯氧基)苯酚。
所述化妆用各组分可以作为单个物质或作为两种或更多种物质的混合物存在于微生物包封材料中。
可微生物包封的化妆品各组分在包封材料中的存在浓度为基于所填充生物胶囊总重的1-80wt%,优选2-60wt%。
化妆品最终配方包括品种非常繁多的化妆品组合物。具体而言,例如以下组合物是适合的:
-护肤组合物,例如皂条或液体皂,合成洗涤剂或洗涤膏形式的皮肤洗涤物和清洁剂,
-浴用制剂,例如液体浴用制剂(泡沫浴、熔体、淋浴制剂)或固体浴用制剂(浴用片剂或浴盐);
-护肤组合物,例如护肤乳液,多功能乳液或护肤油;
-装饰性身体护理组合物,例如日霜或粉霜形式的面用彩妆,扑面粉(疏松或压紧),胭脂或膏状粉底,护眼组合物,例如眼影制剂、睫毛油、眼线膏、眼霜或眼固定霜;唇用护理组合物,例如唇膏、唇彩、唇线笔,指甲护理组合物,例如指甲油、指甲油清洗剂、指甲硬化剂或角质层去除剂;
-个人卫生组合物,例如个人卫生洗涤剂或个人卫生喷雾剂;
-足部护理组合物,例如足浴,足粉,足霜或足用香脂,特殊除臭剂和止汗剂或老茧去除用组合物;
-防晒剂,例如防晒乳液、洗液、霜剂或油,防晒剂或热带用防晒剂,预晒黑药剂或晒后用制剂;
-皮肤晒褐制剂,例如自晒褐霜;
-去色素组合物,例如用于皮肤增白的制剂或用于皮肤增亮的组合物;
-驱虫剂,例如驱虫油,驱虫洗液、喷雾剂或棒剂;
-除臭剂,例如除臭喷雾剂、泵作用喷雾剂、除臭凝胶、棒剂或走珠剂;
-止汗剂,例如止汗剂棒、霜剂或走珠剂;
-清洗或护理瑕疵皮肤的组合物,例如合成洗涤剂(固体或液体),蜕皮或磨擦制剂或蜕皮面膜;
-化学形式的脱毛制剂(脱毛),例如脱毛粉、液体脱毛制剂、霜或糊状脱毛制剂,凝胶形式或气溶胶泡沫形式的脱毛制剂;
-剃须用组合物,例如剃须皂、发泡剃须膏、无泡剃须膏、发泡剂和凝胶剂,干式剃须用的剃须前用制剂,剃须后制剂或剃须后用洗液;
-香料,例如香水(eau de Cologne,eau de toilette,eau deparfum,parfum de toilette,perfume),香精油和香膏;
-用于牙齿、假牙和口腔护理的组合物,例如牙膏、牙膏凝胶剂、牙粉、嗽口水浓缩液、防牙斑漱口剂、假牙清洗剂或假牙粘合剂;
-美发用化妆品组合物,例如香波形式的洗发制剂、护发素,护发组合物,例如预处理组合物,生发油,美发霜,美发凝胶,润发油,洗发水,处理套盒,深度毛发修复剂,毛发成形组合物,例如长效卷发用卷发组合物(热烫、中性烫、冷烫),毛发光滑剂,液体毛发定形组合物,摩丝,喷发胶,增白剂,例如过氧化氢溶液、增亮香波、增白霜、增白粉、增白膏或油,暂时性、半长效或长效染发剂,含有自氧化染料的制剂,或天然染发剂,例如指甲花或春黄菊。
所列出的这些最终配方可以是完全不同的应用形式,例如
-如油/水乳液的液体制剂形式,
-凝胶状,
-油、膏、乳液或洗液状,
-粉、漆、片或配料形式,
-棒状,
-喷雾(用推进剂喷雾或泵喷雾)或气溶胶状,
-泡沫状,或
-糊状。
就此而论,液体和半固体应用形式包括水相的微生物包封材料,以及一种或多种以上列出的功能性化妆品活性组分。固体应用形式包括脱水形式的用微生物包封材料,通常在存在常用助剂下通过冷冻干燥或喷雾干燥脱水。
乳液是非均相体系,由两个彼此不混溶或仅有限混溶的液(相)组成。一个液相是液滴形式(分散相或内相),而另一个液相形成连续相。如果是O/W乳液,其基本性质由水决定,油滴很好地分散在水中。
在室温到皮肤温度的范围内膏剂通常是可铺开的,而洗液或乳液更可能是可流动的。
凝胶是半固体,是或多或少透明的体系,其中所谓的凝胶形成物形成了将液体固定在其中的三维网格。透明到不透明的水凝胶主要由水、水溶性物质以及增稠剂或凝胶形成物组成。如果另外加入脂类,得到外表稍微类似奶油状的水分散凝胶。相反,油凝胶无水并且包含脂类作为液体组分。
根据本发明,包含一种或多种以上列出的可微生物包封组分并且可以以上述应用形式而存在的化妆品最终配方包含的可微生物包封材料的使用浓度优选为0.01-20wt%,优选0.05-10wt%,特别是0.1-5wt%。
本发明进一步提供了这些最终配方。
通常通过将微生物材料与待包封的液态材料在含水介质里混合来进行包封,这是为了使液体在含水介质里形成乳液以便很好地分散并与微生物材料接触。可用冲洗过的微生物或该微生物的含水糊或浆来洗涤可包封的材料,或者在少量水里将可包封的材料与干燥的微生物混合。只需要少量的含水介质。
如果生物胶囊用于制备在牙齿、假牙和口腔护理中使用的包封活性组分,那么可在该生物胶囊中另外加入β-葡聚糖。由于酵母胶囊外壳含β-葡聚糖,生物胶囊可大量到达牙齿和固齿装置(齿龈)的表面上。就漱口水或牙膏而论,与口腔细菌或损害的牙釉质或牙用粘固剂通常只接触约1分钟。由于有大量所述胶囊,活性物质在牙齿区域中滞留时间显著更长。
可以在室温下进行包封,但优选在高温下进行,例如35-60℃,优选40-50℃,并且至少在包封的初始阶段期间,即在第一个30分钟期间采用高温。
可以继续这一处理方法,直到获得最佳的包封。
本发明的化妆品最终配方也可以包含更多的组分,例如柔润剂、乳液稳定剂、皮肤补湿剂、皮肤晒褐加速剂、增稠剂(例如黄原胶)、保湿剂(例如甘油)、防腐剂(例如对羟苯甲酸酯)、抗氧化剂、香料和染料。
通过常用的已知方法制备所述最终配方。
该化妆品最终配方优选用于护理和保护皮肤、粘膜、口腔、指甲或头发,非常特别地是,有防晒剂(所谓的“晒后”用制剂),剃须后制剂,化妆水或除臭剂。
另外,根据本发明使用的生物胶囊也可以用作油溶性染料的运送载体。
因此,本发明还提供权利要求1中的微生物包封材料作为油溶性染料载体体系的用途。
就此而论,适合的染料是合成或天然的那些染料,它们是根据所有已知发色团构造的,例如偶氮、偶氮的、蒽醌、类胡萝卜素、喹啉、呫吨、二芳基甲烷、三芳基甲烷、1,2-二苯乙烯、靛青、酞菁、硝基染料和所有其它的已知发色团,如同也列在Colour Index中C111000-C1 77999下面的那些。
这些染料中,特别有用的是在有机介质(如油类)里至少低程度可溶的那些染料。这些染料包括,例如被称为溶剂染料或分散染料的染料,分散染料也包括一组不带电的直接作用于毛发的染料,例如硝基苯或硝基二苯胺的衍生物。
可根据本发明使用的溶剂染料的例子是:
溶剂黑3(CAS No.:4197-25-5),溶剂黑5(CASNo.11099-03-9);溶剂蓝35(CAS No.12769-17-4);溶剂绿3;溶剂绿7(CAS No.6358-69-6);溶剂橙1(CAS No.2051-85-6);溶剂红24(CAS No.85-83-6);溶剂红43(CAS No.15086-94-9);溶剂红48(CAS No.13473-26-2);溶剂红49:1(CAS No.6373-07-5);溶剂红72(CAS No.596-03-2);溶剂黄44(CASNo.2478-20-8);溶剂黄18(CAS No.6407-76-9)。
可根据本发明使用的分散染料的例子是:
分散黑9(CAS No.12222-60-4);分散蓝1(CAS No.2475-45-8);分散蓝3(CAS No.2475-46-9);分散褐1(CAS No.23355-64-8);分散橙3(CAS No.730-40-5);具有下式的化合物
分散紫1(CAS No.128-95-0);分散紫4(CAS No.1220-94-6);具有下式的化合物
(不带电的)直接作用于毛发的染料的例子:
HC蓝No.2(CAS No.33229-34-4);HC蓝No.4(N-甲基-1,4-二氨基蒽醌,表氯醇和一乙醇胺的反应产物);HC蓝No.5(CASNo.68478-64-8);具有下式的化合物
HC蓝No.7(CAS No.90817-34-8);HC蓝No.8(CAS No.22366-99-0);HC蓝No.9(CAS No.114087-42-2);HC蓝No.10(CASNo.102767-27-1);HC蓝No.11(CAS No.23920-15-2);HC蓝No.12(CAS No.132885-85-9);具有下式的化合物
HC蓝No.14(CAS No.99788-75-7);HC橙No.1(CASNo.54381-08-7);HC橙No.2(CAS No.85765-48-6);HC橙No.3(CASNo.81612-54-6);具有下式的化合物
HC红No.1(CAS No.2784-89-6);HC红No.3(CAS No.2871-01-4);HC红No.7(CAS No.24905-87-1);HC红No.8(CASNo.13556-29-1);HC红No.9(CAS No.56330-88-2);HC红No.10(CASNo.95576-89-9);HC红No.11(CAS No.95576-92-4);HC红No.13(CAS No.94158-13-1);具有下式的化合物
HC黄No.2(CAS No.4926-55-0);HC黄No.4(CAS No.59820-43-8);HC黄No.5(CAS No.56932-44-6);HC黄No.6(CAS No.104335-00-6);具有下式的化合物
HC黄No.8(CAS No.66612-11-1);HC黄No.9(CAS No.86419-69-4);HC黄No.10(CAS No.109023-83-8);HC黄No.11(CASNo.73388-54-2);HC黄No.12(CAS No.59320-13-7);HC黄No.13(CAS No.10442-83-8);具有下式的化合物
具有下式的化合物
HC褐No.1(CAS No.83803-98-9);HC褐No.2(CAS No.83803-99-0);HC绿No.1(CAS No.52136-25-1)。
根据本发明使用的生物胶囊具有以下功能:
-用作载体,使染料穿透某些可能的壁而进入介质,如皮肤、毛发或指甲;
-作为保护物,使染料不受配方其它各组分的作用(反之亦然,作为使该配方不受另一种染料作用的保护物),这是为了,例如消除配方和染料之间的不相容性。然后该染料在纳米分散的范围内,和配方的其余部分分开。因此,例如,可能阻止该染料与其它各组分发生的光引发的链式反应。
-为了在含水体系中加入并稳定仅能溶于油相的染料。
在以下实施例中,百分比都是按重量计算。除非另有说明,就使用的化合物而论,其数量都是按纯物质计。
制备微生物包封的化妆品组分(填充的生物胶囊)
实施例1:
将压紧的发面酵母在蒸馏水中制成浆状,用蒸馏水冲洗几次,并且使用生物离心机28RS(Heraeus)以17,000rpm的转速将其从水相中分离。将75g(干重17.4g)的这一溶液与相当于其干重重量的茶树油在45℃下混合5小时,通过吸收除去过量的茶树油。得到的产品含有63%的包封的茶树油。
实施例2:
通过离心法将251的S.cerevisiae培养物浓缩,并用蒸馏水冲洗若干次。将称重为212g(37.2g干重)的酵母饼与40ml视黄醇5%的甲醇溶液在氮气中35℃下混合4小时。然后干燥酵母胶囊并存储在氮气氛下,直到配制时。该酵母胶囊的视黄醇含量为2.5%。
实施例3:
将20g的干重4.1g的冲洗过的发面酵母与2g抗坏血酸和2g生育酚在乙醇里的混合物于40℃下混合6小时。干燥的酵母胶囊包含总共56%的抗坏血酸/生育酚混合物。
实施例4:
将20g的干重3.9g的冲洗过的啤酒酵母与4g蓝柏油在40℃下混合5小时。干燥的酵母胶囊在研磨后发出强烈的典型蓝柏油味。其包含61%的蓝柏油。
实施例5:
将20g的干重4.1g的冲洗过的发面酵母与4g生育酚醋酸盐在40℃下混合5小时。干燥的酵母胶囊包含总共65%的生育酚醋酸盐。
化妆品最终配方的实施例
实施例6:含维生素A的防晒霜
组成(1)水 至100(2)实施例2的生物胶囊 1.00(3)丙烯酸钠共聚物和豆油以及PPG-1十三烷基
聚氧乙烯(6)醚甲氧基桂皮酸辛酯 2.50(4)右旋泛醇 6.50(5)咪唑烷基脲 0.50(6)苯氧乙醇(和)对羟基苯甲酸甲酯(和)
对羟基苯甲酸丁酯(和) 0.20(7)对羟基苯甲酸乙酯(和)对羟基苯甲
酸丙酯巴巴多芦荟 0.30(8)香料 1.00(9)醇dena t. 0.35(10)丙二醇 8.50(11) 3.00
制备
a.将(1)称重,放入一个清洁、干燥的烧杯;将除了(2)的所有组分相继加入。每加入一个组分都要搅拌混合物。
b.提高搅拌速度,在连续搅拌下加入(2),直到形成调匀并且粘稠的溶液。
实施例7:包含蓝柏油的足霜
组成(1)水 至100(2)实施例4的生物胶囊 2.00(3)丙烯酸钠共聚物和矿物油以及PPG-1十三烷基聚氧
乙烯(6)醚Buxus Chinensis 3.00(4)Persea Gratissima 5.00(5)二甲聚硅氧烷(和)二甲聚硅氧醇 5.00(6)对羟基苯甲酸甲酯钠(和)对羟基苯甲酸丁酯钠(和)钠 10.00(7)对羟基苯甲酸乙酯(和)对羟基苯甲酸丙酯钠 0.10(8)Benzophenone-4 0.15(9)香料 0.10(10)着色剂 适量
制备
a.将(1)称重,放入一个清洁、干燥的烧杯并且开始搅拌。
b.加入(6)、(7)、(8)和(9)并搅拌混合物。
c.随着搅拌,将除了(2)的所有组分以适当的顺序加入。
d.提高搅拌速度并加入(2);进一步搅拌混合物,直到组合物均匀。
实施例8:含有茶树油的漱口水
组成(100%的活性物质)
(A)三氯生 0.05%
(B)甘油 10.0%
乙醇 5.0%
(C)Poloxamer 407 2.0%
(D)糖精钠 0.125%
氟化钠 0.5%
苯甲酸钠 0%
对羟基苯甲酸甲酯 0.2%
对羟基苯甲酸丙酯 0.3%
(E)去离子水 至100.0%
1.1的胶囊 1.0%
香料 适量
制备
将(A)溶解在(B)的混合物中。
通过加热到70℃将(C)溶解在25%的(E)中。
将(D)的各化合物溶解在剩余的E中。
将溶液(A)-(B)加入溶液(C)-(D)。
实施例9:含有蓝柏油的毛发和身体用香波
组成(100%的活性物质)(A)月桂基聚氧乙烯醚硫酸钠 7.8%月桂基聚氧乙烯醚磺基琥珀酸二钠 5.2%聚氧乙烯(7)甘油醚椰油酸酯 4.0%二硬脂酸聚乙二醇(2)酯(和)月桂基聚氧乙烯醚硫酸钠 3.0%月桂基聚氧乙烯(2)醚 1.2%氯化钠 3.0%染料、香料和防腐剂 适量(B)实施例(4)的生物胶囊 2%
去离子水 至100%
制备
将(A)与10%的水混合,直到形成均匀的溶液。用(B)将溶液补足为100%。
实施例10:含有维生素C和维生素E的剃须后用面霜
组成
(1)水 至100
(2)聚季铵盐-37和矿物油以及PPG-1十三烷基聚氧
乙烯(6)醚醇denat. 2.85%
(3)棕榈酸异丙酯 7.50%
(4)辛酸/癸酸甘油三酯 5.00%
(5)甘油 5.00%
(6)实施例3的生物胶囊 4.00%
(7)环甲聚硅氧烷 0.80%
(8)巴巴多芦荟 2.00%
(9)香料 0.20%
(10)辛基三嗪酮 0.10%
(11)对羟基苯甲酸甲酯钠(和)对羟基苯甲酸
丁酯钠(和)钠 0.15%
(12)对羟基苯甲酸乙酯(和)对羟基苯甲酸丙酯钠 0.10%
(13)着色剂 适量
制备
a.将(1)称重,放入一个清洁、干燥的烧杯并开始搅拌。
b.将(11)、(12)、(10)和(13)分散。
c.将除了(2)的所有组分相继加入;在加入每个组分的间隙都要搅拌混合物。
d.提高搅拌速度;加入(2)并搅拌混合物,直到产品粘稠并且均匀。
实施例11:制备微生物包封的氟化物
将100g的干重19.3g的冲洗过的发面酵母悬浮在含有10%硬脂酰三羟乙基亚丙基二胺二氢氟化物(olaflur)的乙醇溶液中,并且在35℃下培养6小时。抽吸过滤并干燥后的酵母胶囊含有22%的硬脂酰三羟乙基亚丙基二胺二氢氟化物。
实施例12:制备微生物包封的4-(2-叔丁基-5-甲基苯氧基)苯酚
将100g的干重18.9g的冲洗过的发面酵母悬浮在含有4-(2-叔丁基-5-甲基苯氧基)苯酚的40%的乙醇溶液中,并且在45℃下培养4小时。抽吸过滤并干燥后的酵母胶囊含有35%的4-(2-叔丁基-5-甲基苯氧基)苯酚。
使用30%的4-(2-叔丁基-5-甲基苯氧基)苯酚在2-丁基-1-辛醇中的溶液并且在50℃下培养31/2小时,得到类似装载量的含4-(2-叔丁基-5-甲基苯氧基)苯酚的胶囊(33%)。
实施例13:制备微生物包封的三氯生
将100g的干重19.5g的冲洗过的发面酵母悬浮在25%浓度的三氯生的乙醇溶液中,并且在45℃下培养5小时。抽吸过滤并干燥后的酵母胶囊含有28%的三氯生。
实施例14:制备含有4-(2-叔丁基-5-甲基苯氧基)苯酚的牙膏 组分
重量百分比蒸馏水 至100山梨醇 34.50Zeodent 113 20甘油 20焦磷酸四钠 12.0焦磷酸二钠 3.40月桂基磷酸钠 1.37香料 1.35PEG-6 1.33Aqualon CMC-9M31XF 1.00根据实施例12制备的生物胶囊 0.5氟化钠 0.50Carbomer 940 0.20糖精-钠 0.20二氧化钛 0.16P-壳聚糖 0.03FD&C蓝(No.1,1%溶液) 0.03
实施例15:制备含有包封的烷基氟化铵的牙膏 组分
重量百分比蒸馏水 至100山梨醇 34.25Zeodent 113 20甘油 20焦磷酸四钠 12.0焦磷酸二钠 3.40月桂基磷酸钠 1.37香料 1.35PEG-6 1.33Aqualon CMC-9M31XF 1.00根据实施例12制备的生物胶囊 0.75氟化钠 0.50
Carbomer 940 0.20
糖精-钠 0.20
二氧化钛 0.16
P-壳聚糖 0.03
FD&C蓝(No.1,1%溶液) 0.03
实施例16:制备含有包封的4-(2-叔丁基-5-甲基苯氧基)苯酚
并能缓释包封氟的烷基氟化铵的牙膏
组分
重量百分比
蒸馏水 至100
山梨醇 34.50
Zeodent 113 20
甘油 20
焦磷酸四钠 12.0
焦磷酸二钠 3.40
月桂基磷酸钠 1.37
香料 1.35
PEG-6 1.33
Aqualon CMC-9M31XF 1.00
根据实施例12制备的生物胶囊 0.5
根据实施例11制备的生物胶囊 0.75
氟化钠 0.50
Carbomer 940 0.20
糖精-钠 0.20
二氧化钛 0.16
P-壳聚糖 0.03
FD&C蓝(No.1,1%溶液) 0.03
实施例17:制备含有包封的三氯生并能缓释包封氟的烷基氟化铵
的牙膏
组分
重量百分比
蒸馏水 至100
山梨醇 34.50
Zeodent 113 20
甘油 20
焦磷酸四钠 12.0
焦磷酸二钠 3.40
月桂基磷酸钠 1.37
香料 1.35
PEG-6 1.33
Aqualon CMC-9M31XF 1.00
根据实施例13制备的生物胶囊 5
根据实施例11制备的生物胶囊 0.75
氟化钠 0.50
Carbomer 940 0.20
糖精-钠 0.20
二氧化钛 0.16
P-壳聚糖 0.03
FD&C蓝(No.1,1%溶液) 0.03
实施例18:制备含有包封的4-(2-叔丁基-5-甲基苯氧基)苯酚的
漱口水
组分
重量百分比
蒸馏水 至100
乙醇 10
甘油 10
Pluronic F108 2
焦磷酸四钠 1.5
香料 1.35
焦磷酸二钠 0.5
根据实施例12制备的生物胶囊 0.5
氟化钠 0.5
糖精-钠 0.3
P-壳聚糖 0.02
实施例19:制备含有包封的三氯生的漱口水
组分
重量百分比
蒸馏水 至100
乙醇 10
甘油 10
Pluronic F108 2
焦磷酸四钠 1.5
香料 1.35
根据实施例13制备的生物胶囊 0.5
焦磷酸二钠 0.5
氟化钠 0.5
糖精-钠 0.3
P-壳聚糖 0.02
实施例20:制备含氟生物胶囊的漱口水
组分
重量百分比
蒸馏水 至100
乙醇 10
甘油 10
Pluronic F108 2
焦磷酸四钠 1.5
香料 1.35
根据实施例11制备的生物胶囊 0.75
焦磷酸二钠 0.5
氟化钠 0.5
糖精-钠 0.3
P-壳聚糖 0.02
实施例21:制备含有4-(2-叔丁基-5-甲基苯氧基)苯酚和烷基氟
的漱口水
组分
重量百分比
蒸馏水 至100
乙醇 10甘油 10Pluronic F108 2焦磷酸四钠 1.5香料 1.35根据实施例11制备的生物胶囊 0.75根据实施例12制备的生物胶囊 0.50焦磷酸二钠 0.5氟化钠 0.5糖精-钠 0.3P-壳聚糖 0.02
实施例22:含有微生物包封的4-(2-叔丁基-5-甲基苯氧基)苯酚
的足霜
(1)水 至100
(2)根据实施例12制备的生物胶囊 2.00
(3)丙烯酸钠共聚物和矿物油以及
PPG-1十三烷基聚氧乙烯(6)醚 3.00
(4)Buxus Chinensis 5.00
(5)Persea Gratissima 5.00
(6)二甲聚硅氧烷(和)二甲聚硅氧醇 10.00
(7)对羟基苯甲酸甲酯钠(和)对羟基苯甲酸
丁酯钠(和)对羟基苯甲酸乙酯钠(和)对
羟基苯甲酸丙酯钠 0.10
(8)Benzophenone-4 0.15
(9)香料 0.10
(10)着色剂 适量
实施例23:含有微生物包封的4-(2-叔丁基-5-甲基苯氧基)苯酚
的足霜(双效)
(1)水 至100
(2)根据实施例4制备的生物胶囊
(3)根据实施例12制备的生物胶囊 2.00(4)丙烯酸钠共聚物和矿物油以及PPG-1十三烷基聚氧乙烯(6)醚 3.00(5)Buxus Chinensis 5.00(6)Persea Gratissima 5.00(7)二甲聚硅氧烷(和)二甲聚硅氧醇 10.00(8)对羟基苯甲酸甲酯钠(和)对羟基苯甲酸丁酯钠(和)对羟基苯甲酸乙酯钠(和)对羟基苯甲酸丙酯钠 0.10(9)Benzophenone-4 0.15(10)香料 0.10(11)着色剂 适量
Claims (18)
1.微生物包封的材料(填充的生物胶囊)在化妆品最终配方中的应用,其中所述生物胶囊含有一种或多种液体或可微生物包封的化妆品组分。
2.权利要求1的应用,其中所述生物胶囊由酵母组成。
3.权利要求1或2的应用,其中所述可微生物包封的化妆品组分选自可用于皮肤的香料和化妆用油类,选自皮肤护理和皮肤清洁物质,选自具有除臭以及止汗作用的活性组分,UV过滤剂,防昆虫的活性组分,用于防化学和机械作用的活性组分,保湿剂物质,具有角膜软化或溶角蛋白作用的活性组分,抗微生物剂,可在皮肤上使用的油性或可溶于油的维生素或维生素衍生物,维生素基胎盘提取物,皮肤修复配合物,植物和植物提取物,动物提取物,染料,抗氧化剂,皮肤晒褐和皮肤增白物质,以及其它化妆用活性组分。
4.权利要求3的应用,其中所述可微生物包封的化妆品组分选自三氯生、二氯生或4-(2-叔丁基-5-甲基苯氧基)苯酚。
5.权利要求1-4任一项的应用,其中所述化妆品各组分作为单独物质或作为两种或更多种物质的混合物存在于微生物包封材料中。
6.权利要求1-5任一项的应用,其中所述可微生物包封的化妆品各组分在包封材料中的存在浓度为基于填充的生物胶囊总重的1-80wt%。
7.权利要求1-6任一项的应用,其中每种所述微生物包封组分在化妆品最终配方中的存在浓度基于化妆品最终配方为0.01-20wt%。
8.凝胶形式的化妆品最终配方,其含有权利要求1中定义的微生物包封材料。
9.膏、洗液或乳液形式的化妆品最终配方,其含有权利要求1中定义的微生物包封材料。
10.棒形的化妆品最终配方,其含有权利要求1中定义的微生物包封材料。
11.喷雾或气溶胶形式的化妆品最终配方,其含有权利要求1中定义的微生物包封材料。
12.泡沫状的化妆品最终配方,其含有权利要求1中定义的微生物包封材料。
13.糊状的化妆品最终配方,其含有权利要求1中定义的微生物包封材料。
14.粉末、漆、片或配料形式的化妆品最终配方,其含有权利要求1中定义的微生物包封材料。
15.权利要求8-14任一项的化妆品最终配方用于护理和保护皮肤、粘膜、口腔、毛发或指甲的用途。
16.权利要求8-14任一项的化妆品最终配方作为防晒剂或“晒后”制剂的用途。
17.权利要求8-14任一项的化妆品最终配方用于剃须或“剃须后”制剂的用途。
18.权利要求8-14任一项的化妆品最终配方用作香水、化妆水或除臭剂的用途。
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP00810021.6 | 2000-01-10 | ||
EP00810021 | 2000-01-10 |
Publications (1)
Publication Number | Publication Date |
---|---|
CN1394135A true CN1394135A (zh) | 2003-01-29 |
Family
ID=8174519
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN01803582A Pending CN1394135A (zh) | 2000-01-10 | 2001-01-04 | 微生物包封的材料在化妆品最终配方中的应用 |
Country Status (7)
Country | Link |
---|---|
US (1) | US20030068347A1 (zh) |
EP (1) | EP1246602A2 (zh) |
JP (1) | JP2003519643A (zh) |
CN (1) | CN1394135A (zh) |
AR (1) | AR026811A1 (zh) |
AU (1) | AU2001223722A1 (zh) |
WO (1) | WO2001051013A2 (zh) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102330348A (zh) * | 2011-07-28 | 2012-01-25 | 吴江征明纺织有限公司 | 一种去臭抑汗防蚊织物用整理剂 |
CN102459556A (zh) * | 2009-06-09 | 2012-05-16 | 德凡化学公司 | 包含微生物的微胶囊 |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ITMI20010207A1 (it) * | 2001-02-02 | 2002-08-02 | Istituto Profilattico Italiano | Composizioni cosmetiche contenenti cellule di lievito naturale |
FR2826570B1 (fr) * | 2001-06-29 | 2005-08-26 | Oreal | Compositions contenant un derive d'hydroxydiphenyl ether inhibant le developpement des odeurs corporelles |
EP1366757A1 (de) * | 2002-05-28 | 2003-12-03 | Ciba SC Holding AG | Verwendung von Hydroxydiphenyletherverbindungen zur Behandlung der Haut |
ES2386433T3 (es) * | 2002-10-09 | 2012-08-21 | The Procter & Gamble Company | Composiciones cosméticas con pegajosidad reducida |
WO2005013931A1 (en) * | 2003-07-16 | 2005-02-17 | Ciba Specialty Chemicals Holding Inc. | Use of halogenated hydroxydiphenyl ether compounds for the treatment of the skin |
GB0322467D0 (en) * | 2003-09-25 | 2003-10-29 | Reckitt Benckiser Uk Ltd | Encapsulated products |
EP1711058B1 (en) | 2004-01-23 | 2021-09-15 | Eden Research Plc | Methods of killing nematodes comprising the application of a terpene component |
GB2413563A (en) * | 2004-04-27 | 2005-11-02 | Micap Plc | Composition comprising a biocide encapsulated within a fungal cell |
EP1753529B1 (en) | 2004-05-20 | 2013-08-14 | Eden Research Plc | Compositions containing a hollow glucan particle or a cell wall particle encapsulating a terpene component, methods of making and using them |
US20080146487A1 (en) * | 2006-12-13 | 2008-06-19 | O'connor Amanda L | Multiphase bathing tablets |
DE102010011335A1 (de) | 2010-03-12 | 2011-09-15 | Beiersdorf Ag | Kosmetische Zubereitungen mit hoch-elastischer Textur |
US9549891B2 (en) | 2012-03-19 | 2017-01-24 | The Procter & Gamble Company | Superabsorbent polymers and sunscreen actives for use in skin care compositions |
ES2860452T3 (es) * | 2015-02-16 | 2021-10-05 | Apirx Pharmaceutical Usa Llc | Composiciones cosméticas y tópicas que comprenden cannabigerol y cannabidiol |
CA2988808C (en) | 2015-06-29 | 2021-05-25 | The Procter & Gamble Company | Superabsorbent polymers, waxes, oils, and starch powders for use in skincare compositions |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4808408A (en) * | 1983-05-11 | 1989-02-28 | Bend Research, Inc. | Microcapsules prepared by coacervation |
US4696863A (en) * | 1984-08-28 | 1987-09-29 | Mitsubishi Paper Mills, Ltd. | Biocapsule |
US4756906A (en) * | 1986-03-18 | 1988-07-12 | Minnesota Mining And Manufacturing Company | Cosmetic colorant compositions |
US5288632A (en) * | 1986-04-12 | 1994-02-22 | Ad2 Limited | Encapsulation of material in microbial cells |
GB8608964D0 (en) * | 1986-04-12 | 1986-05-14 | Pannell N A | Producing microbially encapsulated materials |
GB9509937D0 (en) * | 1995-05-17 | 1995-07-12 | Cpc International Inc | Encapsulated product |
US5941256A (en) * | 1996-12-24 | 1999-08-24 | Gillette Canada Inc. | Dental hygiene article |
-
2001
- 2001-01-04 JP JP2001551437A patent/JP2003519643A/ja active Pending
- 2001-01-04 AU AU2001223722A patent/AU2001223722A1/en not_active Abandoned
- 2001-01-04 WO PCT/EP2001/000051 patent/WO2001051013A2/en not_active Application Discontinuation
- 2001-01-04 US US10/169,700 patent/US20030068347A1/en not_active Abandoned
- 2001-01-04 CN CN01803582A patent/CN1394135A/zh active Pending
- 2001-01-04 EP EP01900122A patent/EP1246602A2/en not_active Withdrawn
- 2001-01-08 AR ARP010100070A patent/AR026811A1/es not_active Application Discontinuation
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102459556A (zh) * | 2009-06-09 | 2012-05-16 | 德凡化学公司 | 包含微生物的微胶囊 |
CN102330348A (zh) * | 2011-07-28 | 2012-01-25 | 吴江征明纺织有限公司 | 一种去臭抑汗防蚊织物用整理剂 |
Also Published As
Publication number | Publication date |
---|---|
WO2001051013A3 (en) | 2002-01-31 |
AR026811A1 (es) | 2003-02-26 |
EP1246602A2 (en) | 2002-10-09 |
AU2001223722A1 (en) | 2001-07-24 |
US20030068347A1 (en) | 2003-04-10 |
WO2001051013A2 (en) | 2001-07-19 |
JP2003519643A (ja) | 2003-06-24 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN1394135A (zh) | 微生物包封的材料在化妆品最终配方中的应用 | |
CN1133414C (zh) | 毫微分散体在化妆品最终制剂中的用途 | |
CN1158061C (zh) | 烃基非挥发性油的防落妆的化妆用组合物 | |
CN1162144C (zh) | 紫外线吸收性组合物 | |
CN1465338A (zh) | 用于外用抗老化制剂的皮肤活化组合物 | |
CN1297266C (zh) | 稳定的抗坏血酸衍生物 | |
US20220047483A1 (en) | Micro-particulate organic uv absorber composition | |
CN1281695A (zh) | 微细颜料混合物用于防止晒黑并使皮肤和头发具有光泽的用途 | |
CN1421197A (zh) | 包含n-乙烯基咪唑聚合物或共聚物和氧化敏感亲水有效成分的化妆和/或皮肤病学组合物 | |
CN101031277A (zh) | 光稳定化妆品或皮肤用组合物 | |
CN1902353A (zh) | 经稳定的身体护理品、家用制品、纺织品和织物 | |
CN1409637A (zh) | 皮肤美化剂、皮肤用抗老化剂、皮肤用增白剂和外用制剂 | |
CN1665475A (zh) | 化妆用部花青衍生物 | |
CN1427707A (zh) | 皮肤外用剂和增白剂 | |
CN1355686A (zh) | 微细颜料混合物 | |
CN1642522A (zh) | 含有羟基苯基三嗪化合物的紫外吸收剂组合物 | |
CN1408339A (zh) | 皮肤外用剂 | |
CN1325293A (zh) | 身体护理品和家庭用品的稳定 | |
CN101039649A (zh) | 抗白发剂 | |
CN1535162A (zh) | 皮肤外用剂 | |
CN1671759A (zh) | 共聚物及其在个人护理组合物中的应用 | |
CN1650845A (zh) | 高脂质含量的可喷雾乳液 | |
CN1376457A (zh) | 含有2,2'-对亚苯基双(3,1-苯并噁嗪-4-酮)的防晒组合物在化妆品和药物制剂中的用途 | |
CN1424020A (zh) | 包含二苯甲酰基甲烷衍生物类防晒剂和氨基取代2-羟基二苯甲酮衍生物的防晒组合物 | |
CN1838938A (zh) | 含有防水香料的化妆品组合物 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
WD01 | Invention patent application deemed withdrawn after publication |