CN1386503A - 治疗酒精中毒和酒精瘾的联合治疗 - Google Patents
治疗酒精中毒和酒精瘾的联合治疗 Download PDFInfo
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- CN1386503A CN1386503A CN02120350A CN02120350A CN1386503A CN 1386503 A CN1386503 A CN 1386503A CN 02120350 A CN02120350 A CN 02120350A CN 02120350 A CN02120350 A CN 02120350A CN 1386503 A CN1386503 A CN 1386503A
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- Prior art keywords
- dichlorophenoxy
- methylamine
- alkyl
- benzyl
- independently selected
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- 125000004193 piperazinyl group Chemical group 0.000 description 1
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- 229920000740 poly(D-lysine) polymer Polymers 0.000 description 1
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- 229920000136 polysorbate Polymers 0.000 description 1
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- JWVCLYRUEFBMGU-UHFFFAOYSA-N quinazoline Chemical compound N1=CN=CC2=CC=CC=C21 JWVCLYRUEFBMGU-UHFFFAOYSA-N 0.000 description 1
- 125000002943 quinolinyl group Chemical group N1=C(C=CC2=CC=CC=C12)* 0.000 description 1
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- 239000003813 safflower oil Substances 0.000 description 1
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- 229910052708 sodium Inorganic materials 0.000 description 1
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- URGAHOPLAPQHLN-UHFFFAOYSA-N sodium aluminosilicate Chemical compound [Na+].[Al+3].[O-][Si]([O-])=O.[O-][Si]([O-])=O URGAHOPLAPQHLN-UHFFFAOYSA-N 0.000 description 1
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- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 description 1
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- 239000008117 stearic acid Substances 0.000 description 1
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- KDYFGRWQOYBRFD-UHFFFAOYSA-L succinate(2-) Chemical compound [O-]C(=O)CCC([O-])=O KDYFGRWQOYBRFD-UHFFFAOYSA-L 0.000 description 1
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- 239000003765 sweetening agent Substances 0.000 description 1
- 229940095064 tartrate Drugs 0.000 description 1
- 125000005958 tetrahydrothienyl group Chemical group 0.000 description 1
- 125000001113 thiadiazolyl group Chemical group 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Addiction (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Psychiatry (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US29308801P | 2001-05-23 | 2001-05-23 | |
| US60/293,088 | 2001-05-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1386503A true CN1386503A (zh) | 2002-12-25 |
Family
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| Application Number | Title | Priority Date | Filing Date |
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| CN02120350A Pending CN1386503A (zh) | 2001-05-23 | 2002-05-23 | 治疗酒精中毒和酒精瘾的联合治疗 |
Country Status (11)
| Country | Link |
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| US (2) | US20030130322A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP1262196A3 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2002370975A (cg-RX-API-DMAC7.html) |
| KR (1) | KR20020090153A (cg-RX-API-DMAC7.html) |
| CN (1) | CN1386503A (cg-RX-API-DMAC7.html) |
| AU (1) | AU4068602A (cg-RX-API-DMAC7.html) |
| CA (1) | CA2386740A1 (cg-RX-API-DMAC7.html) |
| HU (1) | HUP0201722A2 (cg-RX-API-DMAC7.html) |
| NZ (1) | NZ519032A (cg-RX-API-DMAC7.html) |
| PL (1) | PL354110A1 (cg-RX-API-DMAC7.html) |
| ZA (1) | ZA200204019B (cg-RX-API-DMAC7.html) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114588467A (zh) * | 2022-04-01 | 2022-06-07 | 广州蓝仕威克医疗科技有限公司 | 一种基于气体混合比例供气解决酒精中毒的方法及呼吸机 |
| CN115671107A (zh) * | 2022-12-29 | 2023-02-03 | 文韬创新药物研究（北京）有限责任公司 | 用于解酒的复方药物组合物 |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MXPA05011557A (es) * | 2003-04-29 | 2006-03-09 | Orexigen Therapeutics Inc | Composiciones para afectar perdida de peso. |
| US8758443B2 (en) | 2005-05-06 | 2014-06-24 | Titan Spine, Llc | Implants with integration surfaces having regular repeating surface patterns |
| EP2292220A3 (en) | 2005-11-22 | 2012-01-04 | Orexigen Therapeutics, Inc. | Composition and methods for increasing insulin sensitivity |
| WO2007089318A2 (en) * | 2005-11-23 | 2007-08-09 | Orexigen Therapeutics, Inc. | Compositions and methods for reducing food cravings |
| WO2007064586A1 (en) * | 2005-11-28 | 2007-06-07 | Orexigen Therapeutics, Inc. | Methods of treating anxiety disorders |
| US8916195B2 (en) | 2006-06-05 | 2014-12-23 | Orexigen Therapeutics, Inc. | Sustained release formulation of naltrexone |
| CN101588795A (zh) | 2006-11-09 | 2009-11-25 | 奥雷西根治疗公司 | 包含中间快速溶解层的分层药物制剂 |
| AU2007319472B2 (en) | 2006-11-09 | 2013-01-17 | Nalpropion Pharmaceuticals Llc | Methods Of Administering Weight Loss Medications |
| US20100041689A1 (en) * | 2006-12-19 | 2010-02-18 | University Of Virginia Patent Foundation | Combined Effects of Topiramate and Ondansetron on Alcohol Consumption |
| MX2010009509A (es) | 2008-02-28 | 2010-11-30 | Univ Virginia | Gen transportador de serotonina y tratamiento de alcoholismo. |
| US20110144145A1 (en) | 2008-05-30 | 2011-06-16 | Orexigen Therapeutics, Inc. | Methods for treating visceral fat conditions |
| CN102724878A (zh) | 2010-01-11 | 2012-10-10 | 奥雷西根治疗公司 | 在重度抑郁症患者中提供体重减轻疗法的方法 |
| CA2804174A1 (en) | 2010-07-02 | 2012-01-05 | University Of Virginia Patent Foundation | Molecular genetic approach to treatment and diagnosis of alcohol and drug dependence |
| WO2013036721A1 (en) | 2011-09-09 | 2013-03-14 | University Of Virginia Patent Foundation | Molecular genetic approach to treatment and diagnosis of alcohol and drug dependence |
| KR20220042241A (ko) | 2012-06-06 | 2022-04-04 | 오렉시젠 세러퓨틱스 인크. | 과체중 및 비만의 치료 방법 |
Family Cites Families (7)
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| ZA923283B (en) * | 1991-05-29 | 1993-01-27 | Akzo Nv | Phenoxyphenyl derivatives |
| CA2197554A1 (en) * | 1994-09-19 | 1996-03-28 | The Du Pont Merck Pharmaceutical Company | Combination of an opioid antagonist and a selective serotonin reuptake inhibitor for treatment of alcoholism and alcohol dependence |
| US5948807A (en) * | 1997-09-03 | 1999-09-07 | Regents Of The University Of Minnesota | Spiroindanamines and Spiroindanimides |
| EP0945133A1 (en) * | 1998-03-26 | 1999-09-29 | Lipha | Combination for the treatment of alcohol and drug dependence containing an opioid antagonist and a NMDA receptor complex modulator |
| EE200100441A (et) * | 1999-02-23 | 2002-12-16 | Pfizer Products Inc. | Monoamiinide taasomastamise inhibiitorid kesknärvisüsteemi haiguste raviks |
| US6071918A (en) * | 1999-07-21 | 2000-06-06 | Dupont Pharmaceuticals Company | Combination of an opioid antagonist and a selective serotonin reuptake inhibitor for treatment of alcoholism and alcohol dependence |
| YU21602A (sh) * | 1999-10-13 | 2005-06-10 | Pfizer Products Inc. | Derivati biaril etra korisni kao inhibitori ponovnog podizanja monoamina |
-
2002
- 2002-05-02 EP EP02253105A patent/EP1262196A3/en not_active Withdrawn
- 2002-05-08 JP JP2002132804A patent/JP2002370975A/ja not_active Withdrawn
- 2002-05-16 AU AU40686/02A patent/AU4068602A/en not_active Abandoned
- 2002-05-17 CA CA002386740A patent/CA2386740A1/en not_active Abandoned
- 2002-05-17 NZ NZ519032A patent/NZ519032A/en unknown
- 2002-05-21 ZA ZA200204019A patent/ZA200204019B/xx unknown
- 2002-05-22 US US10/153,379 patent/US20030130322A1/en not_active Abandoned
- 2002-05-22 HU HU0201722A patent/HUP0201722A2/hu unknown
- 2002-05-23 CN CN02120350A patent/CN1386503A/zh active Pending
- 2002-05-23 KR KR1020020028682A patent/KR20020090153A/ko not_active Ceased
- 2002-05-23 PL PL02354110A patent/PL354110A1/xx not_active Application Discontinuation
-
2004
- 2004-02-20 US US10/783,196 patent/US20040162316A1/en not_active Abandoned
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114588467A (zh) * | 2022-04-01 | 2022-06-07 | 广州蓝仕威克医疗科技有限公司 | 一种基于气体混合比例供气解决酒精中毒的方法及呼吸机 |
| CN115671107A (zh) * | 2022-12-29 | 2023-02-03 | 文韬创新药物研究（北京）有限责任公司 | 用于解酒的复方药物组合物 |
Also Published As
| Publication number | Publication date |
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| EP1262196A3 (en) | 2002-12-18 |
| AU4068602A (en) | 2002-12-05 |
| KR20020090153A (ko) | 2002-11-30 |
| HUP0201722A2 (hu) | 2003-07-28 |
| US20030130322A1 (en) | 2003-07-10 |
| PL354110A1 (en) | 2002-12-02 |
| EP1262196A2 (en) | 2002-12-04 |
| ZA200204019B (en) | 2003-11-21 |
| NZ519032A (en) | 2003-10-31 |
| HU0201722D0 (cg-RX-API-DMAC7.html) | 2002-07-29 |
| JP2002370975A (ja) | 2002-12-24 |
| CA2386740A1 (en) | 2002-11-23 |
| US20040162316A1 (en) | 2004-08-19 |
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