CN1370240A - 利用ppar核受体的表达调节系统 - Google Patents
利用ppar核受体的表达调节系统 Download PDFInfo
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- CN1370240A CN1370240A CN00811928A CN00811928A CN1370240A CN 1370240 A CN1370240 A CN 1370240A CN 00811928 A CN00811928 A CN 00811928A CN 00811928 A CN00811928 A CN 00811928A CN 1370240 A CN1370240 A CN 1370240A
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/001—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination
- C12N2830/002—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination inducible enhancer/promoter combination, e.g. hypoxia, iron, transcription factor
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/008—Vector systems having a special element relevant for transcription cell type or tissue specific enhancer/promoter combination
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/42—Vector systems having a special element relevant for transcription being an intron or intervening sequence for splicing and/or stability of RNA
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/80—Vector systems having a special element relevant for transcription from vertebrates
- C12N2830/85—Vector systems having a special element relevant for transcription from vertebrates mammalian
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- C12N2840/00—Vectors comprising a special translation-regulating system
- C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron
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- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
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- Zoology (AREA)
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- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
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- Immunology (AREA)
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- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
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Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9907957A FR2795425B1 (fr) | 1999-06-22 | 1999-06-22 | Systeme de regulation pharmacologique de l'expression utilisant les recepteurs nucleaires par et leurs ligands |
| FR99/07957 | 1999-06-22 | ||
| US14972199P | 1999-08-20 | 1999-08-20 | |
| US60/149,721 | 1999-08-20 |
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| CN1370240A true CN1370240A (zh) | 2002-09-18 |
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| CN00811928A Pending CN1370240A (zh) | 1999-06-22 | 2000-06-22 | 利用ppar核受体的表达调节系统 |
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| Country | Link |
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| EP (1) | EP1190084A1 (no) |
| JP (1) | JP2003503034A (no) |
| KR (1) | KR20020028909A (no) |
| CN (1) | CN1370240A (no) |
| AU (1) | AU6164500A (no) |
| BR (1) | BR0011897A (no) |
| CA (1) | CA2375869A1 (no) |
| CZ (1) | CZ20014609A3 (no) |
| HU (1) | HUP0203584A2 (no) |
| IL (1) | IL147104A0 (no) |
| MX (1) | MXPA01013227A (no) |
| NO (1) | NO20016347L (no) |
| NZ (1) | NZ516678A (no) |
| WO (1) | WO2000078986A1 (no) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1263978B1 (fr) * | 2000-03-14 | 2005-12-07 | Universite Pierre Et Marie Curie | Promoteurs hybrides inductibles par l'inflammation, vecteurs les contenant et utilisations |
| EP1288303A1 (en) * | 2001-08-23 | 2003-03-05 | Aventis Pharma S.A. | Inducible expression systems employing PPAR transcriptional activators |
| AU2002333682A1 (en) * | 2001-08-02 | 2003-02-17 | Gencell S.A. | Inducible expression systems employing ppar transcriptional activators |
| US10415054B2 (en) * | 2013-02-04 | 2019-09-17 | Eth Zurich | Designer circuit controlling diet-induced obesity |
| CN107779454A (zh) * | 2016-08-31 | 2018-03-09 | 上海米络凯生物科技有限公司 | 基于PPARγ信号通路的药物筛选模型的构建和应用 |
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| JPH10502256A (ja) * | 1994-07-01 | 1998-03-03 | ザ ソールク インスチチュート フォア バイオロジカル スタディズ | 哺乳動物のペルオキシソーム増殖物質活性化受容体およびその使用 |
| FR2755699B1 (fr) * | 1996-11-08 | 1998-12-18 | Rhone Poulenc Rorer Sa | Nouvelles constructions et vecteurs pour l'expression ciblee et inductible des genes |
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2000
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- 2000-06-22 CA CA002375869A patent/CA2375869A1/fr not_active Abandoned
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- 2000-06-22 WO PCT/FR2000/001744 patent/WO2000078986A1/fr not_active Application Discontinuation
- 2000-06-22 AU AU61645/00A patent/AU6164500A/en not_active Abandoned
- 2000-06-22 EP EP00948058A patent/EP1190084A1/fr not_active Withdrawn
- 2000-06-22 BR BR0011897-4A patent/BR0011897A/pt not_active IP Right Cessation
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Also Published As
| Publication number | Publication date |
|---|---|
| NO20016347L (no) | 2002-02-19 |
| CZ20014609A3 (cs) | 2002-05-15 |
| BR0011897A (pt) | 2002-03-26 |
| NZ516678A (en) | 2004-04-30 |
| JP2003503034A (ja) | 2003-01-28 |
| WO2000078986B1 (fr) | 2001-04-19 |
| WO2000078986A1 (fr) | 2000-12-28 |
| KR20020028909A (ko) | 2002-04-17 |
| MXPA01013227A (es) | 2002-06-04 |
| HUP0203584A2 (hu) | 2003-02-28 |
| IL147104A0 (en) | 2002-08-14 |
| AU6164500A (en) | 2001-01-09 |
| NO20016347D0 (no) | 2001-12-21 |
| EP1190084A1 (fr) | 2002-03-27 |
| CA2375869A1 (fr) | 2000-12-28 |
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