CN1363397A - Process for preparing medical suture bio-silk from goat intestines - Google Patents
Process for preparing medical suture bio-silk from goat intestines Download PDFInfo
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- CN1363397A CN1363397A CN 02115412 CN02115412A CN1363397A CN 1363397 A CN1363397 A CN 1363397A CN 02115412 CN02115412 CN 02115412 CN 02115412 A CN02115412 A CN 02115412A CN 1363397 A CN1363397 A CN 1363397A
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- goat
- line body
- casing
- silk
- hydrogen peroxide
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Abstract
A medical silk is prepared from goat intestine through washing, longitudinally cutting to obtain 2-4 strip, washing internal surface, immersing in solution of sodium hydroxide for 1-3 days, washing, bleaching in 0.1-0.4% H2O2 for 4-8 hrs, coating collagen, mechanically preparing silk, drying in air, polishing, loading in protecting liquid, sterilizing and packing. Its advantages include simple process, excellent performance, and high strength.
Description
Technical field
The present invention relates to a kind of manufacture method of medical operation surgery auxiliary material, particularly a kind of process for preparing medical suture bio-silk from goat intestines.
Figure viewed from behind technology
At present, home and abroad medical operation surgical sutures commonly used still mainly is the medical catgut made from the sheep casing.This medical catgut manufacturing is simple, with low cost, and degraded, absorbed by the intravital catabolic enzyme of people easily behind the implant into body by human body, and noresidue in patient's human body, have no side effect.Yet, because inherent life of sheep and physiological property determine, its casing is easy to aging and normal ill knot, add that traditional processing method is perfect not to the utmost again, so the anti-ultimate strength of existing sheep intestinal medical catgut and anti-knotting ultimate strength are all lower, result in hand cramps for the medical operating operator and inconvenience.Thereby people are exploring its improved process and its alternative articles for use.
Summary of the invention
Purpose of the present invention just is to overcome above-mentioned defective of the prior art, it is still comparatively extensive to propose a kind of raw material sources, processing technique is also comparatively simple, the casing characteristic is more excellent, anti-ultimate strength of the medical catgut that is made into and all higher process for preparing medical suture bio-silk from goat intestines of anti-knotting ultimate strength.
Purpose of the present invention mainly is to reach by implementing following technical proposal: the goat casing of cleaning is vertically broken into the 2--4 bar equably, and the sodium hydroxide solution of putting into 10--30% behind the clean casing inwall soaked 1--3 days; Take out to clean, use 0.1--0.4% at normal temperatures hydrogen peroxide bleaching 4--8 hour, take out the back at its surface applied animal collagen, reach line body softness; Dry by the machinery system line and the tension of putting on the shelf at normal temperatures, with buffing machine the line body is polished then, make the line body bright and clean; Through physical property detect qualified after, reperfusion protection liquid is also sterilized, packs, is put in storage line body and protection liquid.
The present invention can also obtain better technique effect by implementing following technical measures: the goat casing surface applied (concrete animal collagen) after process sodium hydroxide solution and hydrogen peroxide bleaching processing; The line body that has poured into protection liquid is carried out cobalt-60 radiosterilization to be handled; After handling through hydrogen peroxide bleaching, goat casing is put down system processing, repaste applies animal collagen and post processing thereof; After handling through hydrogen peroxide bleaching, goat casing is carried out the processing of chromium system, repaste applies animal collagen and post processing thereof.
The present invention compared with prior art, it is still comparatively extensive to have raw material sources, processing technique is also comparatively simple, the casing characteristic is more excellent, anti-ultimate strength of medical bio stitching thread that is made into and anti-knotting ultimate strength are fit to be used for substitute existing sheep intestinal medical catgut all than characteristics such as height.
The specific embodiment
Embodiment 1
The goat casing of cleaning is broken into even 4, clean and to put into 15% sodium hydroxide solution behind the casing inwall and soaked 2 days, the back is taken out and is cleaned, used 0.2% hydrogen peroxide bleaching at normal temperatures 8 hours, repaste applies animal collagen, reaches line body softness, back machinery is made line, is put on the shelf, dries, with buffing machine the line body is polished then, detect, make the line body bright and clean through physical property.Reperfusion protection liquid is to line body sterilization protection, and it is not dry, not crisp that the line body is preserved moisture, and at last the stitching thread that sterilization protection liquid is housed is sterilized.
Embodiment 2
The goat casing of cleaning is broken into even 3, clean and put into 30% sodium hydroxide solution behind the casing inwall and soaked 2 days, take out afterwash, used 0.1% hydrogen peroxide bleaching at normal temperatures 5 hours, casing is put into 0.3 ‰ chrome liquors, increase acetate simultaneously, carry out deciding chromium, washing back coating animal collagen, reach line body softness, back machinery is made line, is dried, and with buffing machine the line body is polished then, detect through physical property, make the line body bright and clean.Reperfusion protection liquid makes the insulation of line body not dry, not crisp to line body sterilization protection, at last the stitching thread that sterilization protection liquid is housed is sterilized.Animal collagen extracts from mammal (as cattle, sheep etc.) connective tissue with enzyme digestion.
Claims (3)
1, a kind of process for preparing medical suture bio-silk from goat intestines is characterized in that: the goat casing of cleaning is vertically broken into the 2--4 bar equably, and the sodium hydroxide solution of putting into 10--30% behind the clean casing inwall soaked 1--3 days; Take out to clean, use 0.1--0.4% at normal temperatures hydrogen peroxide bleaching 4--8 hour, take out the back at its surface applied animal collagen, reach line body softness; Dry by the machinery system line and the tension of putting on the shelf at normal temperatures, with buffing machine the line body is polished then, make the line body bright and clean; Through physical property detect qualified after, reperfusion protection liquid is also sterilized, packs, is put in storage line body and protection liquid.
2, process for preparing medical suture bio-silk from goat intestines according to claim 1 is characterized in that: the goat casing surface applied animal collagen after process sodium hydroxide solution and hydrogen peroxide bleaching processing; The line body that has poured into protection liquid is carried out cobalt-60 radiosterilization to be handled; After handling through hydrogen peroxide bleaching, goat casing is put down system processing, repaste applies animal collagen and post processing thereof.
3, process for preparing medical suture bio-silk from goat intestines according to claim 1 is characterized in that: the goat casing surface applied animal collagen after process sodium hydroxide solution and hydrogen peroxide bleaching processing; The line body that has poured into protection liquid is carried out cobalt-60 radiosterilization handle after handling through hydrogen peroxide bleaching, goat casing is carried out the processing of chromium system, repaste applies animal collagen and post processing thereof.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 02115412 CN1363397A (en) | 2002-01-08 | 2002-01-08 | Process for preparing medical suture bio-silk from goat intestines |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 02115412 CN1363397A (en) | 2002-01-08 | 2002-01-08 | Process for preparing medical suture bio-silk from goat intestines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1363397A true CN1363397A (en) | 2002-08-14 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 02115412 Pending CN1363397A (en) | 2002-01-08 | 2002-01-08 | Process for preparing medical suture bio-silk from goat intestines |
Country Status (1)
| Country | Link |
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| CN (1) | CN1363397A (en) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101455858B (en) * | 2009-01-04 | 2012-05-23 | 张玉福 | Biology collagen brown medical soft suture-thread manufacture method |
| CN103638552A (en) * | 2013-12-12 | 2014-03-19 | 董新义 | Preparation method of biochemical complexing off-white medical absorbable suture line |
| CN104069541A (en) * | 2013-12-04 | 2014-10-01 | 江西龙腾生物高科技有限公司 | Preparation method of collagen suture line |
| CN107875435A (en) * | 2017-11-21 | 2018-04-06 | 菏泽海诺知识产权服务有限公司 | A kind of preparation technology of absorbability medical catgut |
| CN107970487A (en) * | 2017-12-26 | 2018-05-01 | 徐州仁和医疗科技有限公司 | A kind of novel medical operation suture |
| CN113941024A (en) * | 2021-10-20 | 2022-01-18 | 山东康利达医用制品有限公司 | Manufacturing process and application of medical absorbable bovine intestine suture line |
| WO2022095028A1 (en) * | 2020-11-07 | 2022-05-12 | 单县华宇缝合制品有限公司 | High-strength biological suture line and preparation method therefor |
-
2002
- 2002-01-08 CN CN 02115412 patent/CN1363397A/en active Pending
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101455858B (en) * | 2009-01-04 | 2012-05-23 | 张玉福 | Biology collagen brown medical soft suture-thread manufacture method |
| CN104069541A (en) * | 2013-12-04 | 2014-10-01 | 江西龙腾生物高科技有限公司 | Preparation method of collagen suture line |
| CN103638552A (en) * | 2013-12-12 | 2014-03-19 | 董新义 | Preparation method of biochemical complexing off-white medical absorbable suture line |
| CN107875435A (en) * | 2017-11-21 | 2018-04-06 | 菏泽海诺知识产权服务有限公司 | A kind of preparation technology of absorbability medical catgut |
| CN107970487A (en) * | 2017-12-26 | 2018-05-01 | 徐州仁和医疗科技有限公司 | A kind of novel medical operation suture |
| CN107970487B (en) * | 2017-12-26 | 2021-01-26 | 杭州整形医院有限公司 | Novel medical operation suture line |
| WO2022095028A1 (en) * | 2020-11-07 | 2022-05-12 | 单县华宇缝合制品有限公司 | High-strength biological suture line and preparation method therefor |
| CN113941024A (en) * | 2021-10-20 | 2022-01-18 | 山东康利达医用制品有限公司 | Manufacturing process and application of medical absorbable bovine intestine suture line |
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| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |