CN1072086A

CN1072086A - The preparation method of cover biomembrane for wound of burn and scald

Info

Publication number: CN1072086A
Application number: CN92106059A
Authority: CN
Inventors: 郝振林; 杨奕
Original assignee: Individual
Current assignee: Individual
Priority date: 1992-02-22
Filing date: 1992-02-22
Publication date: 1993-05-19

Abstract

The present invention is a kind of biomembrane preparation method that is used for the empyrosis wound surface treatment.It is to get human body fetal lamb film to clean through distilled water, puts into normal saline and adds animal proteinum to scattering, again rinsing 5-10 minutes repeatedly, being pure white is hyaline membrane, take out drop water purification branch for 2-4 times with the sterile saline flushing, put into the peracetic acid immersion then and cushion film forming, the sealing stored refrigerated.The cover biomembrane that the present invention is made owing to have sterilization, bacteriostasis, has reduced the generation that burn wound infects.Use it, empyrosis wound surface only need cover once until recovery from illness, need not change dressings, and has alleviated patient's misery and medical personnel's labor intensity.

Description

The preparation method of cover biomembrane for wound of burn and scald

The present invention relates to treat the medicine of empyrosis wound surface, specifically a kind of biomembrane preparation method that is used for the empyrosis wound surface treatment.

Skin is the more important and complicated vital organ of human body, if burn and scald occurs, severe patient not only organizes base dead, and loses original structure of skin and function, destroys the homeostasis of human body." burn toxin " that forms and whole body " stress " reflection etc., can cause each system complex and serious pathophysiological change, cause serious consequence until threat to life.

According to the high temperature burn and scald degree of injury of skin is divided into three degree, i.e. I degree burn and scald, II degree burn and scald, III degree burn and scald.For the Therapeutic Method of burn and scald, normally adopt: 1, occlusive dressing; 2, exposure method; 3, wet treatment; 4, operative therapy etc.Above-mentioned first three planted therapy, and its course of treatment is long, is easy to infect, and it is loaded down with trivial details to change dressings, and nursery work is heavy, has increased medical personnel's labor intensity.Operative therapy is easy to leave over spot, damages normal skin in operation process easily, and the patient suffering is big.The biomembrane covering therapy of immediate development is to adopt artificial skin and animal skins that wound surface is covered, and it can only solve skin source deficiency, reduces at the bottom of the protection machine and pollutes, and does not have the therapeutical effect to wound surface.

The objective of the invention is shortcoming at above-mentioned existence, provide a kind of empyrosis wound surface is treated not easy infection of short treating period, wound surface, the patient suffering is little, and dressing change frequency is few, and can alleviate labor intensity in medical personnel's nursing process, cover biomembrane medicine processing process.

Technical essential of the present invention is:

Getting human body fetal lamb film cleans through distilled water, put into normal saline and add animal proteinum to scattering, being pure white repeatedly in rinsing 5-10 minute again is hyaline membrane, takes out drop water purification branch for 2-4 time with the sterile saline flushing, put into the peracetic acid immersion then and cushion film forming, the sealing stored refrigerated.Used fetal lamb film should obtain making in 2 hours after the healthy pregnant women Placenta Hominis is given birth to, and summer, be good winter in 12 hours with in 6 hours.

The cover biomembrane that the present invention is made owing to have sterilization, bacteriostasis, has reduced the generation that burn wound infects.It is strong to have occupancy, and form-dependent character is good, and elasticity is strong, can protect nutrient and lose with immunoglobulin and advantage such as lose, and the function of approximate skin is arranged.Use its empyrosis wound surface to cover, need not change dressings, alleviated patient's misery and medical personnel's labor intensity once until recovery from illness.This coverlay avirulence comes off voluntarily with healing Colaesce crust at the bottom of the wound surface machine, alleviates malunion.Its preparation technology's method is simple, is easy to popularize, and is suitable for all kinds of medical applications.

Said peracetic acid immersion is that to get 14% peracetic acid, 95% ethanol, sterile saline formulated in the ratio of 0.5-2: 10-15: 500-900 among the present invention.

Specific embodiment is: will take from the fetal lamb film that the healthy pregnant women Placenta Hominis is given birth to, and put into that distilled water will wash out white macula on the fetal membrane, bloodstain, (presenting the cellophane cover shape) is placed on normal saline and adds animal embryo albumen and scatter to divest chorion.Rinsing made it be the pure white hyaline membrane in 10 minutes repeatedly again, after sterile saline flushing three times, took out drop water purification branch.After being put in the peracetic acid physiological water immersion enamel dish for preparing in advance buffering, exercise again with or to put into 3-5 ℃ of refrigerator preservation of sealing bottles placement stand-by.During use, empyrosis wound surface is carried out conventional debridement, reject dead epidermis, the foreign body of base, with antiseptic gauze dipping 0.02% peracetic acid liquid soak 10-30 minute, carry out pad pasting (the edge 1-2cm of film) then, film is outer needn't to add any dressing wrapping.Incrustation in 5-7 hour behind the pad pasting, if having localized membrane come off, dry or split because of activity and can study for a second time courses one has flunked pad pasting again, repeatedly repeat the film secure bond of sticking together.This coverlay injures that to cover therapeutic effect for the skin-grafting area wound surface good being used for I, II, III degree burn and scald, makes that the patient suffering is few, the treatment short treating period, reduces medical expense.I, II are not left over spot after more, and function is accessible, kept machine at the bottom of granulation fresh, reduced antibiotic application.This coverlay also can be used for surgical operation edge of a knife healing, and surgery skin and flesh is hindered sticks that maxillofacial trauma is handled and decubital ulcer etc.

Claims

1, a kind of preparation method of cover biomembrane for wound of burn and scald, it is characterized in that getting human body fetal lamb film cleans through distilled water, put into normal saline and add animal proteinum to scattering, being pure white repeatedly in rinsing 5-10 minute again is hyaline membrane, take out drop water purification branch for 2-4 time with the sterile saline flushing, put into the peracetic acid immersion then and cushion film forming, the sealing stored refrigerated.

2,, it is characterized in that said peracetic acid immersion is that to get 14% peracetic acid, 95% ethanol, sterile saline formulated in the ratio of 0.5-2: 10-15: 500-900 according to the described preparation method of claim 1.