CN105536035B - The method and device thereof of castor otter tail portion tendon production suture - Google Patents
The method and device thereof of castor otter tail portion tendon production suture Download PDFInfo
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- CN105536035B CN105536035B CN201610107926.XA CN201610107926A CN105536035B CN 105536035 B CN105536035 B CN 105536035B CN 201610107926 A CN201610107926 A CN 201610107926A CN 105536035 B CN105536035 B CN 105536035B
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- castor
- tail portion
- otter
- roller
- tendon tissue
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L17/00—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
- A61L17/06—At least partially resorbable materials
- A61L17/08—At least partially resorbable materials of animal origin, e.g. catgut, collagen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L17/00—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
- A61L17/14—Post-treatment to improve physical properties
-
- D—TEXTILES; PAPER
- D02—YARNS; MECHANICAL FINISHING OF YARNS OR ROPES; WARPING OR BEAMING
- D02G—CRIMPING OR CURLING FIBRES, FILAMENTS, THREADS, OR YARNS; YARNS OR THREADS
- D02G3/00—Yarns or threads, e.g. fancy yarns; Processes or apparatus for the production thereof, not otherwise provided for
- D02G3/02—Yarns or threads characterised by the material or by the materials from which they are made
Abstract
The method that a kind of castor otter tail portion tendon makes suture, it is main comprising steps of castor otter tail portion tendon tissue is extracted, the processing of castor otter tail portion tendon tissue, carried out stretching cleaning, offline, detection, packaging using special tensioner.Wherein tensioner, including base support, motor, pulley, roller, drum shaft, bearing block, press strip, arc bristle brush mounting plate, bristle brush.The utility model has the advantages that 1. suture obtained has pure-natural biological originality；2. it absorbs completely, it is without side-effects；3. histocompatbility is good；4. suture surface is smooth, item is dry uniformly, and line footpath is accurate, and has ideal tensile strength.Tensioner one can fix a large amount of castor otter tail portion tendon tissue, high-efficient；And while stretching its tensile strength of guarantee to castor otter tail portion tendon tissue is fixed, moreover it is possible to clear up castor otter tail portion tendon tissue, improve the cleannes and smoothness of product, reduce feeling of pain of the patient in operation stitching.
Description
Technical field
The present invention relates to field of biomedicine technology, and in particular to a kind of absorbable doctor of castor otter tail portion tendon tissue production
With the method and device thereof of suture.
Background technique
Currently, well known surgical operation mainly has three cutting, hemostasis and suture basic operations, it is necessary when stopping blooding and suturing
Use suture.There are many kinds of classes for suture, can be divided into two kinds according to biodegradability, one kind is non-absorbable suture
Line, it is non-degradable in vivo, stays in the tissue if not taken out by operation as body foreign matter；Another kind is absorbable suture
Line, it can usually be disappeared from implantation point after one month by being degraded into soluble product in vivo.Using non-absorbable
Suture sutures epidermis, especially skin of face, can make skin scar, the suture for internal organs, using absorbable
Suture has the advantages that incomparable, it can provide temporary bracket or barrier for body, and can lead to after completing mission
Cross and be degraded into the absorbable substance of human body and disappear, avoid the rejection generated in vivo by long-term existence alien material,
Non-infectious inflammation and some other undesirable element influence, while taking out stitches after also avoiding wound healing to pain caused by patient
Hardship reduces infected chance, accelerates the working efficiency of medical worker, thus medically, it and non-absorbable operation
Suture, which is compared, has apparent advantage, receives the favor of numerous doctors and patient with operation, be it is a kind of with development potential
Absorbable type biomaterial.
2. 1. ideal medical absorbable suture can carry out thorough disinfection and sterilization processing there are six basic demand has
Certain mechanical performance, such as mechanical strength appropriate and ductility, there is certain flexibility and elastic recovery, there is certain moisten
Intensity and coefficient of friction are easy to operate when 3. suturing, knotting, and the functional 4. suture of knot certain time in vivo is held after making knots
It is interior to keep certain intensity, and can be absorbed after wound healing and 5. have adaptability to tissue, not reason foreign body reaction
And the 6. stable and reliable product quality that is inflamed, it is easy to make, it is cheap and easy to get.The absorbable suture that the country uses at present is main
It is catgut, catgut by being absorbed by the body after a certain period of time, does not stay foreign matter, but Boardy Feeling, knot difficult, and need in vivo
It is immersed in the organic solvents such as dimethylbenzene, there is bad smell.
It is dynamic to belong to Rodentia, castor Muridae, a kind of precious fur of castor Mustella for castor otter, also known as natural pond leopard cat, nutria etc.
Object.Castor otter tail portion tendon tissue makes absorbable medical suture, and chemical component is collagen, has unique texture
Family's protein, is widely present in mammalian tissues, accounts for about 50% of gross protein or more.It for bone, skin, sarolemma and
Ligament provides biomechanical property, is in triple helix structure, is made of three polypeptide chains, each collagen chain is all left hand helix
Configuration, three left hand helixs.One chain twines into mutually right-handed helix structure, i.e. superhelix again, under polarization optics microscope
It can be seen that tropocollagen molecule joins end to end, and laterally it is gathered into microfibre.Tropocollagen molecule is arranged in subfiber in microfibre
Space lattice structure, subfiber are grouped together into the collagenous fibres of observable period band-like style under Electronic Speculum, and more
Collagenous fibres are assembled into fibre bundle unit by certain rule, are arrangement of collagen fibers into wave shaped topography.Under force-extension, waveform
It is gradually gentle, or even straight line can be pulled into, the waveform construction of exactly this fibre bundle makes it have the elasticity of height, is drawing repeatedly
The lower structure that will not destroy tropocollagen molecule on nanoscale of pressure effect.Afterbody structure is by two or three tow groups
At film.This multi-level tissue of collagen makes strong with toughness.Under excessive stress, layer of structure at different levels can
The mutually coordinated movement of energy, until partial failure.In this way, energy as much as possible can be absorbed in each unit so that whole as one
The tendon of body is unlikely to damage.It thus is seen that the natural structure of collagen is that castor otter tail portion tendon can be used to the suture that operates
And the key with stronger mechanical property, have the advantages that 2. numerous unique 1. human tolerances well have certain antibacterial
Antiinflammation can promote wound healing, and the small 3. intensity of scar and flexibility are moderate, and skin-friction coefficient is small, be easy to suture and beat
4. knot can carry out routine disinfection, can also be dyed, uniform absorption after 5. the specially treateds such as anti-corrosion be implanted intos, and strength retrogression's rate is fitted
In, being able to satisfy requirement of the wound healing overall process to suture intensity, 6. raw material sources are wide, and simple processing is at low cost.
Currently known castor otter tendon suture manufacturing technique method is: 1. put to death animal, are generally shaken using brain
Swing method；2. sterile water repeated flushing tendon tissue is used, until silvery white is presented；3. in manually or mechanically method by the tendon of cleaning
The line of required thickness and length is made in tissue；4. being placed in 75% ethyl alcohol to impregnate 24 hours, it is allowed to fixed dehydration, degreasing, line obtained
5-40cm, thickness 30-1000um, with Co 60 radiation sterilization.But this method has the following problems: 1, chemical residual is toxic
Effect, is unfavorable for human health；2, tensile strength is inadequate, is unable to satisfy needs.And its used tensioner is generally
Lineation frame, this device have the following deficiencies: the castor otter tail portion flesh that 1, lineation frame is capable of fixing in the actual production process
Tendinous tissue limited amount, enterprise need to complete work using a large amount of lineation frame；2, a large amount of lineation frame needs large area
Place is dried, and brings the trouble of lack of space to enterprise；3, the fixed stretching castor otter that this lineation frame can only be simple
Tail portion tendon tissue, and it cannot be cleared up, the smoothness of castor otter tail portion tendon tissue is inadequate, and patient has in suture
Very strong feeling of pain.
Summary of the invention
To solve the above problems, the object of the present invention is to provide a kind of sides of castor otter tail portion tendon production suture
Method.
The purpose of the present invention is achieved through the following technical solutions:
The method that a kind of castor otter tail portion tendon makes suture, includes the following steps:
(1) castor otter tail portion tendon tissue extracts: meeting animal welfare, healthy living body castor otter is put to death, in aseptic condition
Lower extraction castor otter tail
Portion's tendon tissue, process are as follows: qualified castor otter is placed in closing by living body health castor otter weight, tail length measurement
It in formula water, cruises 30-60 minutes, then be placed in closed clean room, carbon dioxide narcosis, bloodletting, tail portion is cleaned, with 75% second
The disinfection of alcohol tail skin cuts in tail end 0.5cm at transverse direction with skin and cuts off tail point skin, longitudinally cuts off tail skin to root of the tail portion,
Exposure tail portion joint tissue carries out joint and fractures to extract tendon tissue with coccyx pincers from coccyx distal end, with line cut separation joint with
Tendon tissue, with sterile water wash 2-3 times；
(2) castor otter tail portion tendon tissue is handled: it is small that castor otter tail portion tendon tissue is placed in 75% ethyl alcohol immersion 12-24
When, it is allowed to fixed dehydration,
Degreasing sterilization；75% ethyl alcohol is prepared using 95% ethyl alcohol and distilled water；
(3) it uses special tensioner: castor otter tail portion tendon tissue one end is fixed on press strip, it then will pressure
Item is mounted on roller, and castor otter tail portion tendon tissue is attached on roller；Motor drives roller slowly to rotate, and bristle brush is revolved in roller
The castor otter tail portion tendon tissue of cylinder surface is adjacent to and lifted when turning, while castor otter tail portion tendon tissue is drawn
It stretches and clears up, keep its surface smooth；
(4) offline: to screen the tendon tissue met the requirements of the standard, isolate different size model, pressed with passive pressure machine
Different model specification wears the not damaged perforating needle or fluting needle of different size, and band needle suture is made；
(5) it detects: detecting thickness and length, the uniformity, needlework Connected degree by root；
(6) pack: certified products is packaged into the solid wire that nontoxic aluminium foil bag puts on dragon flying around paper bag in 8-shaped with nontoxic paper yarn card,
Co-60 radiation sterilizing, the time 48 hours；Finished product class wrapping, carries out factory testing, the detection of physical chemistry sterility test, it is qualified at
Product storage.
A kind of castor otter tail portion tendon makes tensioner used in suture production, including base support, electricity
Machine, belt pulley, roller, drum shaft, bearing block, press strip, arc bristle brush mounting plate, bristle brush are placed with motor on base support, electricity
Machine output shaft is connect by belt with belt pulley, and belt pulley is fixed on the end of roller, and roller is fixed on drum shaft, drum shaft
It is fixed on base support by bearing block；Castor otter tail portion tendon is fixed on press strip, and press strip is mounted on roller；Roller
It is fixed with arc bristle brush mounting plate on the base support of lower section, bristle brush, roller just forward and backward side are installed on arc bristle brush mounting plate
And bristle brush is respectively and fixedly provided on the base support of diagonally forward.
Beneficial effects of the present invention: 1. the suture as made from this method has pure-natural biological originality；2. having absorbed
Entirely, without side-effects；3. histocompatbility is good；4. surface is smooth, easily sterilize；5. suture surface is smooth, item is dry uniformly, and line footpath is quasi-
Really, and there is ideal tensile strength, suture tensile strength is high, can meet clinical requirement, meet and exceed middle Chinese
The performance requirement of people republic pharmaceuticals industry standard YY 1116-2002 " absorbable surgical sutures ".Tensioner in the present invention
One can fix a large amount of castor otter tail portion tendon tissue, high-efficient；Occupied ground is smaller, has saved production for enterprise and has used
Ground；And while stretching its tensile strength of guarantee to castor otter tail portion tendon tissue is fixed, moreover it is possible to castor otter tail portion flesh
Tendinous tissue is cleared up, and the cleannes and smoothness of product are improved, and reduces feeling of pain of the patient in operation stitching.
Detailed description of the invention
Fig. 1 is tensioner structural side view used in the present invention.
Fig. 2 is tensioner structure front view used in the present invention.
Specific embodiment
The present invention can be described in more detail in the following examples, but the invention is not limited in any way.
Embodiment:
A kind of castor otter tail portion tendon makes tensioner used in suture production, as shown in Figure 1, 2, pedestal
Motor 2 is placed on bracket 1,2 output shaft of motor is connect by belt with belt pulley 3, and belt pulley 3 is fixed on the end of roller 4,
Roller 4 is fixed on drum shaft 5, and drum shaft 5 is fixed on base support 1 by bearing block 6；Roller 4 is equipped with press strip 7, sea
Leopard cat otter tail portion tendon 10 is fixed on press strip 7, and press strip 7 is mounted on roller 4；It is fixed on the lower section base support 1 of roller 4
Arc bristle brush mounting plate 8 is equipped with the pedestal branch of bristle brush 9, the just forward and backward side of roller 4 and diagonally forward on arc bristle brush mounting plate 8
Bristle brush 9 is respectively and fixedly provided on frame 1.
The method that a kind of castor otter tail portion tendon makes suture, includes the following steps:
(1) castor otter tail portion tendon tissue extracts: meeting animal welfare, healthy living body castor otter is put to death, in aseptic condition
Lower extraction castor otter tail
Portion's tendon tissue, process are as follows: qualified castor otter is placed in closing by living body health castor otter weight, tail length measurement
It in formula water, cruises 30-60 minutes, then be placed in closed clean room, carbon dioxide narcosis, bloodletting, tail portion is cleaned, with 75% second
The disinfection of alcohol tail skin cuts in tail end 0.5cm at transverse direction with skin and cuts off tail point skin, longitudinally cuts off tail skin to root of the tail portion,
Exposure tail portion joint tissue carries out joint and fractures to extract tendon tissue with coccyx pincers from coccyx distal end, with line cut separation joint with
Tendon tissue, with sterile water wash 2-3 times；
(2) castor otter tail portion tendon tissue is handled: it is small that castor otter tail portion tendon tissue is placed in 75% ethyl alcohol immersion 12-24
When, it is allowed to fixed dehydration,
Degreasing sterilization；75% ethyl alcohol is prepared using 95% ethyl alcohol and distilled water；
(3) it uses special tensioner: castor otter tail portion tendon tissue one end is fixed on press strip, it then will pressure
Item is mounted on roller, and castor otter tail portion tendon tissue is attached on roller；Motor drives roller slowly to rotate, and bristle brush is revolved in roller
The castor otter tail portion tendon tissue of cylinder surface is adjacent to and lifted when turning, while castor otter tail portion tendon tissue is drawn
It stretches and clears up, keep its surface smooth；
(4) offline: to screen the tendon tissue met the requirements of the standard, isolate different size model, pressed with passive pressure machine
Different model specification wears the not damaged perforating needle or fluting needle of different size, and band needle suture is made；
(5) it detects: detecting thickness and length, the uniformity, needlework Connected degree by root；
(6) pack: certified products is packaged into the solid wire that nontoxic aluminium foil bag puts on dragon flying around paper bag in 8-shaped with nontoxic paper yarn card,
Co-60 radiation sterilizing, the time 48 hours；Finished product class wrapping, carries out factory testing, the detection of physical chemistry sterility test, it is qualified at
Product storage.
The above description of the embodiment is only used to help understand the method for the present invention and its core ideas.It should be pointed out that pair
For those skilled in the art, without departing from the principle of the present invention, the present invention can also be carried out
Some improvements and modifications, these improvements and modifications also fall within the scope of protection of the claims of the present invention.
Claims (2)
1. a kind of method of castor otter tail portion tendon production suture, which comprises the steps of:
(1) castor otter tail portion tendon tissue extracts: meeting animal welfare, puts to death healthy living body castor otter, aseptically mention
Take castor otter tail
Portion's tendon tissue, process are as follows: qualified castor otter is placed in closed pond by living body health castor otter weight, tail length measurement
It in water, cruises 30-60 minutes, then be placed in closed clean room, carbon dioxide narcosis, bloodletting, tail portion is cleaned, with 75% ethyl alcohol tail
Portion's skin degerming is cut with skin and laterally cuts off tail point skin at tail end 0.5cm, longitudinally cuts off tail skin to root of the tail portion, exposure
Tail portion joint tissue carries out joint and fractures to extract tendon tissue, cut with line and separate joint and tendon with coccyx pincers from coccyx distal end
Tissue, with sterile water wash 2-3 times；
(2) castor otter tail portion tendon tissue is handled: castor otter tail portion tendon tissue is placed in 75% ethyl alcohol and impregnates 12-24 hours, makes
Fixation dehydration,
Degreasing sterilization；75% ethyl alcohol is prepared using 95% ethyl alcohol and distilled water；
(3) it uses special tensioner: castor otter tail portion tendon tissue one end being fixed on press strip, then pacifies press strip
On roller, castor otter tail portion tendon tissue is attached on roller；Motor drives roller slowly to rotate, and bristle brush is rotated in roller
When be adjacent to and lift the castor otter tail portion tendon tissue of cylinder surface, while to castor otter tail portion tendon tissue stretched with
And cleaning, keep its surface smooth；
(4) offline: to screen the tendon tissue met the requirements of the standard, isolate different size model, with passive pressure machine by difference
Model specification wears the not damaged perforating needle or fluting needle of different size, and band needle suture is made；
(5) it detects: detecting thickness and length, the uniformity, needlework Connected degree by root；
(6) pack: certified products is packaged into the solid wire that nontoxic aluminium foil bag puts on dragon flying around paper bag, Co 60 in 8-shaped with nontoxic paper yarn card
Radiation sterilization, the time 48 hours；Finished product class wrapping, carries out factory testing, the detection of physical chemistry sterility test, and qualified finished product enters
Library.
2. a kind of castor otter tail portion tendon makes tensioner used in suture production, including base support (1), electricity
Machine (2), belt pulley (3), roller (4), drum shaft (5), bearing block (6), press strip (7), arc bristle brush mounting plate (8), bristle brush
(9), it is characterised in that: be placed on base support (1) motor (2), motor (2) output shaft is connected by belt and belt pulley (3)
It connects, belt pulley (3) is fixed on the end of roller (4), and roller (4) is fixed on drum shaft (5), and drum shaft (5) passes through bearing block
(6) it is fixed on base support (1)；Castor otter tail portion tendon (10) is fixed on press strip (7), and press strip (7) is mounted on roller (4)
On；It is fixed with arc bristle brush mounting plate (8) on the lower section base support (1) of roller (4), pacifies on arc bristle brush mounting plate (8)
Equipped with bristle brush (9), bristle brush (9) are further fixed on the base support (1) of the just forward and backward side of roller (4) and diagonally forward.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610107926.XA CN105536035B (en) | 2016-02-29 | 2016-02-29 | The method and device thereof of castor otter tail portion tendon production suture |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610107926.XA CN105536035B (en) | 2016-02-29 | 2016-02-29 | The method and device thereof of castor otter tail portion tendon production suture |
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| Publication Number | Publication Date |
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| CN105536035A CN105536035A (en) | 2016-05-04 |
| CN105536035B true CN105536035B (en) | 2019-02-26 |
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Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN112281337A (en) * | 2020-08-21 | 2021-01-29 | 苏州乾冠新纺织科技有限公司 | Cleaning device is used in production of mosquito repellent surface fabric |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050033362A1 (en) * | 2001-09-13 | 2005-02-10 | Grafton R. Donald | High strength suture with collagen fibers |
| CN101085373A (en) * | 2006-06-09 | 2007-12-12 | 湖南然原医用高科技蛋白线有限公司 | Method for producing nutria tendon tissue medical suture and straining device for the same |
| CN200957207Y (en) * | 2006-06-23 | 2007-10-10 | 湖南然原医用高科技蛋白线有限公司 | Tensioner for production of medical suture from muscle tendon of beaver |
| CN105031716A (en) * | 2015-07-03 | 2015-11-11 | 郑国洲 | Method for extracting collagen line from internal of nutria |
| CN205411752U (en) * | 2016-02-29 | 2016-08-03 | 唐孟元 | Tension device who uses in production of beaver otter afterbody tendon preparation surgical suture |
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Effective date of registration: 20230724 Address after: 518000, Building 2, Building 428, Henglang New Industrial Zone, Henglang Community, Dalang Street, Longhua District, Shenzhen City, Guangdong Province Patentee after: Shenzhen Shizu Intellectual Property Service Co.,Ltd. Address before: 415400 Organ of the Standing Committee of Changde Municipal People's Congress Patentee before: Tang Mengyuan |