CN101085373A - Method for producing nutria tendon tissue medical suture and straining device for the same - Google Patents

Method for producing nutria tendon tissue medical suture and straining device for the same Download PDF

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Publication number
CN101085373A
CN101085373A CN 200610031794 CN200610031794A CN101085373A CN 101085373 A CN101085373 A CN 101085373A CN 200610031794 CN200610031794 CN 200610031794 CN 200610031794 A CN200610031794 A CN 200610031794A CN 101085373 A CN101085373 A CN 101085373A
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CN
China
Prior art keywords
coypu
tendon tissue
medical suture
suture
tendon
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CN 200610031794
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Chinese (zh)
Inventor
佘爱军
史桂香
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RANYUAN MEDICAL HI-TECH BOTEIN LINE Co Ltd
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RANYUAN MEDICAL HI-TECH BOTEIN LINE Co Ltd
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Priority to CN 200610031794 priority Critical patent/CN101085373A/en
Publication of CN101085373A publication Critical patent/CN101085373A/en
Pending legal-status Critical Current

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Abstract

The invention discloses a production method of suture prepared from nutria tendon tissue and its tensioner. The method comprises extracting tendon tissue from nutria, dewatering, degreasing, sterilizing, air-drying under tensile force, screening to obtain qualified tissue, separating out suture of different specification, and matching with non damage perforate pin or notch pin according to specification, and preparing into sutural line with pin. The inventive suture needle has smooth surface, uniform strip, accurate linear diameter, and good tensile force.

Description

Coypu tendon tissue medical suture manufacturing technique method and tensioner thereof
Technical field
The present invention relates to a kind ofly make the processing method of suture, be mainly the production process method that production and processing after extracting, handle at the coypu tendon tissue becomes product line with the coypu tendon tissue.
Background technology
At present the production method of the public coypu tendon tissue medical suture of knowing only be embodied in extract tendon tissue in the coypu body and extract after material processing method, it is the method for coypu tendon tissue biological treatment, do not finish later concrete process of manufacture and do not relate to the biological treatment of coypu tendon tissue, promptly the coypu tendon tissue is processed into the manufacture method of suture.Known coypu tendon tissue medical suture extracts and bioremediation is: 1, put to death animal, aseptic relatively extraction spinal column is main muscle rhabdomyosarcoma tendinous tissue; 2, clean the tendon tissue that is extracted repeatedly with sterilized water, till presenting silvery white; 3, according to the need and possibility, with artificial or mechanical means the tendon tissue that cleans is made the line of required thickness and length; 4, the line in the step 3 was placed 75% soak with ethanol 24 hours, make it to fix, dehydration, defat and sterilization.In the practice process, the manufacturing process of step 3 is: with manually-operated the material that cleaning finishes is placed operating table surface, give free rein to and dry back reuse slide gauge and carry out linear diameter measurement and carry out linear measure longimetry with ruler, to tell the line of required thickness and length, its prepared line length is at 5-40cm, the about 30-1000 μ of thickness m.Treat to pack with nonpoisonous plastic film after step 4 is finished, reuse cobalt 60 radiation sterilizations form.The major defect of this method is: 1, clean the material finish in natural dry process, material can be because of the bending of shrinking and becoming naturally, cause suture line body bar to be done and to satisfy evenly, rough, in follow-up slotted line body diameter process, easily cause result error, thereby cause thread tension can not satisfy clinical instructions for use, have risk to a certain degree; 2, suture is made the back for not being with the pin stitching thread, in clinical use, the doctor needs to mix the plain bore sewing needle according to the interim selection of tension force size of cutting part and suture, cause the actual use of suture length to shorten simultaneously, be unfavorable for the operation use, also use and bring very big trouble and inconvenience to the clinician.And the technology of other synthesising biological absorbable sutures all is separation and Extraction, pulverizing, chemosynthesis and knitting forming in the animal body, has all changed the original structure of raw material in its process, has carried out the material structure reorganization, has added a certain amount of chemical constituent simultaneously.After it is absorbed by the body, all there is small amount of chemical substances residual, human body is all had to a certain degree toxic action, be in security risk.
Summary of the invention
Be the defective of avoiding existing in the aforesaid operations method, and the new generation product of producing health, environmental protection, green, my company has carried out brand-new exploration to coypu tendon tissue medical suture manufacturing technique method, and has created a cover manufacturing technique method.
Purpose of the present invention aims to provide a kind of coypu tendon tissue medical suture manufacturing technique method, this method is made medical suture needle with the tendon tissue that extracts in the coypu and is had the suture smooth surface, bar is done evenly, and the line footpath is accurate, and ideal tensile strength is arranged.
Another object of the present invention aims to provide a kind of tensioner that makes the tendon tissue that extracts in the coypu reach ideal tensile strength.
The objective of the invention is to realize by following manner:
The tendon tissue that will extract from coypu is through dehydration, defat and sterilization treatment, then the coypu tendon tissue is dried under tension state, the qualified coypu tendon tissue of screening is isolated the suture of different size model, wear the not damaged perforating needle or the fluting pin of different size at last by the different model specification, thereby make band pin stitching thread.
Described tension state is in dry process, one end of the coypu tendon tissue handled well is fixed, the other end is under the shrink tension of elastic thread all the time, thereby the coypu tendon tissue that reaches hygrometric state can be because of the purpose of shrinking and buckling naturally, coypu tendon tissue bar after finally having guaranteed to dry is done evenly, smooth surface.
Tensioner of the present invention is seen Fig. 1 for reason line basket, and reason line basket is the frame shape thing of a hollow, one side of frame shape thing is fixed with several connectors, its relative opposite side is connected with elastic thread, and coypu tendon tissue one end links to each other with connector, and the other end is connected with elastic thread.
Described connector is the steel folder.
Described elastic thread one end hanging sleeve is on the pillar on another relative side of frame shape thing, and the other end then is connected with the steel folder.
The coypu tendon tissue medical suture that process produced according to the invention is made, its performance meets YY1116-2002 " absorbability surgical sutures " standard-required fully, the suture smooth surface, bar is done evenly, the line footpath accurately, have ideal tensile strength, be furnished with sewing needle, can make things convenient for the clinician to use.
The coypu tendon tissue medical suture that manufacturing technique method of the present invention is made is the reality single cord, and its production process does not change the original structure of raw material, does not add any chemical constituent, has guaranteed the pure biological of the pure natural property of raw material and product.
The coypu tendon tissue medical suture that manufacturing technique method of the present invention is made can require to wear by not collinear footpath the medical suture needle of different size according to clinical different operative sites, has specificity, can provide multiregion to select to use the line model to the clinician.The trouble and the artificial too short defective of suture length of threading a needle in the operation use have been avoided because of not being with medical suture needle simultaneously temporarily.
The coypu tendon tissue medical suture that manufacturing technique method of the present invention is made, the clinical operation of nearly 2000 examples of the whole nation tens tame big-and-middle-sized hospitals such as a refined hospital, refined two hospitals in Hunan, Hunan, refined three hospitals in Hunan, Hunan, People's Hospital, Hunan Prov., Shanghai Long March Hospital, middle mountain hospital and Shanghai Sixth Man people hospital uses in Hunan, Hunan, obtain good result, doctor, patient feel quite pleased.
The coypu tendon tissue medical suture that manufacturing technique method of the present invention is made, more ripe more than the coypu tendon tissue medical suture that additive method is made, technology is more perfect, be more suitable for suitability for industrialized production, on market, can form more strong competitive advantage, thereby can replace partial synthesis absorbable suture product, create huge economic benefit and social benefit.
Description of drawings
Fig. 1 is the structural representation of tensioner of the present invention.
The specific embodiment
Embodiment
(1), raw material (coypu tendon tissue) extracts: put to death healthy live body coypu, adopting molding raw material extractive technique to carry out the extraction of coypu tendon tissue, molding raw material extractive technique process such as figure below under the aseptic condition relatively:
The healthy coypu body weight of live body, long measurements → cerebral concussion executions of tail, blood-letting → cleaning afterbody, with 75% ethanol tail skin sterilize → cut with skin and laterally cut off the sharp skin of tail in tail end 0.5cm place, vertically cut off tail skin again to root of the tail portion, exposing afterbody joint tissue → with coccyx clamps from the coccyx far-end and carries out the joint extraction tendon tissue that fractures, till distance root of the tail portion joint 10cm place → cut with line and to separate joint and tendon tissue, and tendon tissue cleaned promptly to finish for 2-3 time to extract with sterilized water operate.
(2), raw material (coypu tendon tissue) handles: the coypu tendon tissue after will extracting places 75% ethanol to soak 12-24 hour, makes it to fix, dehydration, defat and sterilize.The tendon tissue that is not silvery white in color of part was carried out being placed on after the rinsing (1-2 hour) in 75% ethanol immersion 12-24 hour with 0.5% sodium nitrite solution again.The medical ethanol and the distilled water of 75% ethanol employing 95% are formulated.
(3), tension force reason line: the method with physical mechanics makes the coypu tendon tissue in the air dried process of tension state.This process adopts that reason is traditional thread binding to be comprised fully: reason line basket 1, see Fig. 1, it is the rectangle frame shape thing of a hollow, be made with all steel, one side of frame shape thing is installed a little steel folder 5 every 2cm, its relative opposite side is connected with elastic thread 3 (elastic force rubber band), and described elastic thread 3 one end hanging sleeves are on the pillar 2 on another relative side of frame shape thing, and elastic thread 3 other ends then are connected with steel folder 4 (totally 25).See Fig. 1.
With coypu tendon tissue 6 by between corresponding two the little steel folders up and down of the fixing resonable line basket of root, totally 25, adopt the tension force after fixedly the elastic force rubber band of the little steel folder of downside is stretched, make every coypu tendon tissue in dry process, be in tension state all the time, go through and to dry in 30-60 minute, thereby can guarantee that the coypu tendon tissue is after the dry state bar and does evenly smooth surface.
(4), roll off the production line: use artificial method, the process that the air dried coypu tendon tissue of step 3 is screened.Unaccommodated coypu tendon tissue can be screened away by this step, the tendon tissue that aperture standardization requires, thus guaranteed the quality of material.
(5), card survey line: the line of the coypu tendon tissue of step 4 being isolated the coypu tendon tissue of dry state with artificial or mechanical method different size model (thickness and length).
(6), band pin: the suture that step 5 is made is worn the not damaged perforating needle or the fluting pin of different size with passive forcing press by the different model specification, thereby make band pin stitching thread.
(7), process detects: the made band pin stitching thread of step 6 is pursued root by the different model specification detect, comprise the suture bar evenness, needlework connection degree.
(8), interior bag: be the figure of eight with nontoxic paper yarn card and pack tightly the solid wire packaging process that the nontoxic aluminium foil bag of packing into puts the dragon flying around paper bag again to detecting qualified certified products line.
(9), cobalt 60 sterilizations: the 60 pairs of every batch of products of cobalt with 18KGY dosage carry out irradiation sterilization, sterilization time 48 hours.
(10), outsourcing: the finished product that sterilization is finished carries out the process of class wrapping, every in 10 in box, box in every case 24.
(11), the detection of dispatching from the factory: the product of step 9 is carried out the process of physics, chemistry and sterility test sampling Detection, whether satisfy the operative norm requirement with what this judged every batch of product.
(12), finished product warehouse-in: detect qualified finished product through dispatching from the factory, enter the process that finished room is stored.

Claims (6)

1, coypu tendon tissue medical suture manufacturing technique method, the tendon tissue that will extract from coypu is through dehydration, defat and sterilization treatment, then the coypu tendon tissue is dried under tension state, the qualified coypu tendon tissue of screening is isolated the suture of different size model, wear the not damaged perforating needle or the fluting pin of different size at last by the different model specification, thereby make band pin stitching thread.
2, coypu tendon tissue medical suture manufacturing technique method according to claim 1, tension state is in dry process, and an end of the coypu tendon tissue handled well is fixed, the other end is under the shrink tension of elastic thread all the time.
3, the tensioner during the coypu tendon tissue medical suture is produced, tensioner is a reason line basket, reason line basket is the frame shape thing of a hollow, one side of frame shape thing is fixed with several connectors, its relative opposite side is connected with elastic thread, coypu tendon tissue one end links to each other with connector, and the other end is connected with elastic thread.
4, the tensioner during coypu tendon tissue medical suture according to claim 3 is produced, described connector are the steel folder.
5, the tensioner during coypu tendon tissue medical suture according to claim 3 is produced, described elastic thread one end hanging sleeve are on the pillar on another relative side of frame shape thing, and the other end then is connected with the steel folder.
6, the tensioner during coypu tendon tissue medical suture according to claim 3 is produced, described elastic thread is the elastic force rubber band.
CN 200610031794 2006-06-09 2006-06-09 Method for producing nutria tendon tissue medical suture and straining device for the same Pending CN101085373A (en)

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CN 200610031794 CN101085373A (en) 2006-06-09 2006-06-09 Method for producing nutria tendon tissue medical suture and straining device for the same

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Application Number Priority Date Filing Date Title
CN 200610031794 CN101085373A (en) 2006-06-09 2006-06-09 Method for producing nutria tendon tissue medical suture and straining device for the same

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CN101085373A true CN101085373A (en) 2007-12-12

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102188745A (en) * 2011-04-19 2011-09-21 陈启忠 Preparation method of medical suture thread by drawing nutria tail tendon
CN104548192A (en) * 2013-10-16 2015-04-29 周峰 Preparation method of collagen suture lines
CN104841007A (en) * 2015-06-10 2015-08-19 湖南然元医用高科技蛋白线有限公司 Medical suture line and preparation method thereof
CN105031716A (en) * 2015-07-03 2015-11-11 郑国洲 Method for extracting collagen line from internal of nutria
CN105536035A (en) * 2016-02-29 2016-05-04 唐孟元 Method and device for preparing medical sutures from tail tendons of beavers

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102188745A (en) * 2011-04-19 2011-09-21 陈启忠 Preparation method of medical suture thread by drawing nutria tail tendon
CN102188745B (en) * 2011-04-19 2013-10-02 陈启忠 Preparation method of medical suture thread by drawing nutria tail tendon
CN104548192A (en) * 2013-10-16 2015-04-29 周峰 Preparation method of collagen suture lines
CN104841007A (en) * 2015-06-10 2015-08-19 湖南然元医用高科技蛋白线有限公司 Medical suture line and preparation method thereof
CN104841007B (en) * 2015-06-10 2016-06-01 湖南然元医用高科技蛋白线有限公司 A kind of suture and its preparation method
CN105031716A (en) * 2015-07-03 2015-11-11 郑国洲 Method for extracting collagen line from internal of nutria
CN105536035A (en) * 2016-02-29 2016-05-04 唐孟元 Method and device for preparing medical sutures from tail tendons of beavers

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Open date: 20071212