CN1359260A

CN1359260A - Anti-bacterial composition and use thereof for skin care and fabric treatment

Info

Publication number: CN1359260A
Application number: CN00809753A
Authority: CN
Inventors: 雅各布·丹尼利
Original assignee: Sintal International Inc
Current assignee: Sintal International Inc
Priority date: 1999-04-30
Filing date: 2000-04-28
Publication date: 2002-07-17
Also published as: HK1048416A1; WO2000065911A1; EP1179980A1; EP1179980A4

Abstract

This invention relates to a water-based composition having at least one of anti-bacterial or anti-fungal properties and use thereof for skin care and for fabric treatment. The composition is not only effective as an anti-bacterial and/or anti-fungal material when included in a skin care gel or lotion for topical use, such as in a sun screen composition, or in conjunction with sanitary elastic gloves as a coating therein, it is gentle to the user's skin and may include constituents which advantageously indicate its presence. The composition is not only effective as an anti-bacterial and/or anti-fungal material when used as a liquid to treat fabric employed for personal hygiene aids including disposable diapers for children and adults, sanitary napkins, and wipes, it is gentle to the skin and may be formulated to provide odor control. Users include humans and animals.

Description

Be used as bactericidal composition of skin nursing and fabric processing and uses thereof

The present invention relates to have the aqueous composition of at least a antibiotic or antifungal property and the purposes of handling as skin nursing and fabric thereof.When adding said composition in the skin nursing gel that uses on the surface or emulsion such as the suncream, or when making health elastomeric glove coating, it not only has antibiotic and/or antifungic action, and very soft to user's skin, can also comprise the composition that shows its existence easily.Personal hygiene article comprises children and the square disposable diaper of the usefulness of being grown up when said composition is used as, and during fabric treatment fluids such as sanitary napkin and paper handkerchief, it not only has antibiotic and/or antifungic action, and very soft to skin, can also be deployed into the control smell.The user comprises humans and animals.

Approximately since in May, 1997, the inventor starts selling a kind of emulsion, and this emulsion is an aqueous composition, and commodity are called tSHIELD ^TM(Quest Research, Inc.), when handling mammilla of milk cattle after milk cow is milked preceding or milks and in the dry run, it is used as effective antibiotic barrier.The said composition prescription is mainly as the maceration extract of comforting maceration extract or rag material.Its product emulsion can make the skin of milk cow avoid the bacterium infringement up to more than 4 days, can show its existence with dye marker, and therefore a kind of effective indicator is provided.

Said composition comprises four kinds of antibacterial activity compositions at the target bacteria of finding usually in using, promptly, weight percent meter with whole composition, 0.30% Quaterniunm 12 (C.T.F.A., i.e. beauty treatment, makeup and the (Cosmetic of perfume association, Toiletries, andFragrances Association) title), as BORDAC 2250, a kind of disinfectant that Lonza company produces; 2.80% hexadecane trimethyl sal-ammoniac (C.T.F.A. by name), it is 16 (alkane) base-trimethyl ammonium chloride, a kind of disinfectant that Lonza company produces, its trade name is CARSOQUAT CT-429; The combination of 2.80% docosane trimethyl sal-ammoniac first sulphide and octadecanol (by name C.T.F.A.), it is the disinfectant that a kind of ISP Co., Ltd produces; With 0.10% 16 (alkane) basic pyridinium chloride father-in-law.

Said composition also comprises in order to improve the silicones liquid of this liquid and cow teat viscosity, silicones as 0.90% (SILICONE) 344 and 0.70% silicones (SILICONE) 1401 (Dow Corning manufacturing), and other composition comprises emulsifier, colouring agent is as the FD﹠amp of about 0.0023 weight %; C is red, and spices and thinner are as about deionized water of 85% to 90%.

About in May, 1998, the inventor begins a kind of aqueous-based gel compositions of offering for sale greatly, especially uses it to have antibacterial action when the people washes one's hands in medical hygiene, and its trade name is QUATRO-DERM ^TM(Quest Research, Inc.).Said composition comprises four kinds of active components, so called after " quarto ", that is, with the weight percent meter of whole composition, 0.1% Quaternium 12 (C.T.F.A. by name), as BORDAC 2250, a kind of disinfectant that Lonza company produces; Didecyl-dimethyl ammonium chloride of 0.5%; 1.0% hexadecane trimethyl sal-ammoniac (by name C.T.F.A.), i.e. 16 (alkane) base-trimethyl ammonium chloride, a kind of disinfectant that Lonza company produces, its trade name is CARSOQUAT CT-429; With 0.04% CHG20% (gluconic acid chlorine pyridine DegussaAG is made).

Said composition also comprises many other compositions, as 1.25% methylcellulose 40-101 (Dow Chemical's production) as thickener, make the viscosity of composition increase about 4000 centipoises and 0.5%GERMABEN II (making), as the formaldehyde material of composition by ISP company.

Said composition is to soft not as expection of user's skin, and subject matter is the lability of color and because the existence of GERMABEN II in no case can be removed formaldehyde.

An object of the present invention is to provide a kind of bactericidal composition, said composition is soft, can be reusable, the human and animal is had effective antibacterial action.

Another object of the present invention provides a kind of bactericidal composition, and said composition is soft, can be reusable, the human and animal is had effective antibacterial action, with after can't see residual trace but still have lasting functional activity.

A further object of the present invention provides a kind of antifungal composition, and said composition is soft, can be reusable, the human and animal is had effective antifungic action.

Another object of the present invention provides a kind of hygiene tissue, as disposable diaper (children and adult), lady's panty liner, and men's and lady's paper handkerchief, but the women is used for groin, rectum, inner ear, the eyelid cleaning has special effect with the removal of the cosmetics that contact with skin, and this hygiene tissue comprises the present invention and has antibiotic and composition antifungic action.

In order to realize these and other purposes of the present composition, the invention provides a kind of composition, it is a kind of colloid or emulsion, at least has a kind of antibiotic or antifungal property, said composition comprises the pure water of 85 weight % to 90 weight %, as deionized water, the hexadecane trimethyl sal-ammoniac of 0.80 weight % to 1.3 weight %; With at least a zephiran chloride and the grapefruit seed profit reduction and reserving thing of being selected from that is 0.07 weight % to 0.08 weight %; 0.15 didecyl-alkyl dimethyl ammonium chloride to 0.35 weight %; With 0.08% to 1.55% Quaternium 22.

Described gel or emulsion compositions are a kind of nontoxic, and be non-inflammable, moist, non-irritating cleaning agent.It is soft, and the pH equilibrium does not retain residue in body part such as wet nurse's breast or breast milk.

Composition of the present invention does not contain the toxicity metal, as arsenic, though do not contain formaldehyde, but still the very long protection period is arranged.Composition is enough soft, is suitable for the skin of any kind, include, but are not limited to, and lip, breast, groin, rectum and zone near the eyes can be reused and be free from side effects.

The present invention also provides and has been selected from following hygiene tissue, comprises disposable diaper, and lady's panty liner and paper handkerchief comprise combined fabric; With a kind of aqueous composition, it comprises the water of 85 weight % to 90% weight; 2.20 docosane trimethyl sal-ammoniac first sulphide and the octadecanol of weight % to 3.00 weight %, the Quaternium 12 of 0.15 weight % to 0.33 weight %; 0.80 the hexadecane trimethyl sal-ammoniac of weight % to 3.00 weight %; With the certain herbaceous plants with big flowers base pyridinium chloride father-in-law of 0.08 weight % to 1.55 weight %, the quantity of existence should make the combined fabric surface that contacts with the user have effectively antibiotic and/or antifungal property at least.The amount ranges of composition reaches the moisture that should not suppress combined plant and is absorbed as suitable.Preferred paper handkerchief is to be full of aqueous composition fully, and is made by non-fabric, comprises nature material such as cotton paper pulp, or synthetic material such as polyester fiber.

The present invention further provides a kind of sanitary glove, comprised the gloves that constitute by elastomeric material; With the coating that inner surface to the small part of gloves has, this coating comprises aqueous composition, and said composition has at least a antibiotic or antifungal property, and it comprises the water of 85 weight % to 90 weight %; 2.20 docosane trimethyl sal-ammoniac first sulphide and the octadecanol of weight % to 3.00 weight %; 0.15 the Quaternium 12 of weight % to 0.33 weight %; 0.80 the Cetrimonium chloride of weight to 3.00 weight %; With the basic pyridinium chloride father-in-law of 0.08 to 1.55% certain herbaceous plants with big flowers.

The present invention comprises four kinds of antibacterial activity compositions as the composition of skin nursing, promptly, 0.80 weight % to 1.3 weight %, be preferably hexadecane trimethyl sal-ammoniac and 0.07 weight % to the 0.08 weight % of 1.20 weight %, at least a zephiran chloride and the grapefruit seed profit reduction and reserving thing of being selected from of preferred 0.08 weight %; 0.15 weight % to 0.35 weight % is preferably didecyl-alkyl dimethyl ammonium chloride of 0.30 weight %; 0.08 weight % to 1.55 weight %, the Quaternium 22 (title C.T.F.A.) of preferred 0.1 weight % is as being made by Lonza company, as those products of effective antimicrobial component.These materials are also very effective as anti-mycotic material.When one or more of this four kinds of active components when using than small concentration, their preservative agents that are used as more.

Composition of the present invention can also comprise thickener, as 0.09 weight % to 1.20 weight %, and the NATRASOOL HHR250 that produces by Aqualon company of preferred 1.00 weight % or the methylcellulose 40-401 that produces by Tao Shi.

Said composition also comprises wetting agent, as about 0.09 weight % to 0.12 weight %, the aloe extract of preferred 0.10 weight %.Can also comprise lanolin or glycerine, also can add other materials, as vitamin E and citric acid.

Said composition also comprises a kind of composition of effective adjusting smell, that is, 1.00 weight % to 2.50 weight %, the sodium salt of organic sesquicarbonate of preferred 2.50 weight % is as the product of Dow Chemical's production.

The bactericidal composition of using health elastomeric glove of the present invention comprises four kinds of effective active antibacterial compositions, that is, 0.15 weight % to 0.33 weight %, the Quaternium12 of preferred 0.30 weight % (title C.T.F.A.) is as the product of Lonza company manufacturing; 0.80 weight % to 3.00 weight % is preferably the hexadecane trimethyl sal-ammoniac of 2.80 weight %; 2.20 weight % to 3.00 weight %, be preferably 2.80 weight %% docosane trimethyl sal-ammoniac first sulphide and octadecanol (title C.T.F.A.); With 0.08 weight % to 1.55 weight %, the certain herbaceous plants with big flowers of preferred 0.10 weight % base pyridinium chloride father-in-law (title C.T.F.A.), the product of the effective antimicrobial component of producing as Croda company of conduct.These materials also can be used as antimycotic material.

Composition of the present invention can also comprise thickener, as 0.80 weight % to 1.20 weight %, be preferably the CYCLOMETHICONE that produces by Dow Chemical of 0.90 weight % and 0.05 weight % to the 0.90 weight % that produces by DOW Chemical, be preferably the CYCLOMETHICONE DIMETHICONOL of 0.07 weight %.

Said composition also comprises wetting agent, as 0.09 weight % to 0.12 weight %, is preferably aloe extract, vitamin E and the glycerine of 0.10 weight %.

Said composition can also add a kind of composition of effective adjusting smell, that is, 1.00 weight % to 2.50 weight % are preferably the sodium salt of organic sesquicarbonate of 2.50 weight %.

Said composition can also comprise a kind of activated indicators, and whether it instructs the user to find whether composition is effective by the existence of color or smell.For example, can use a kind of dyestuff, only be also non-limiting for example, as FD﹠amp; Red #28 of C or red fluorescence #40.And dyestuff can be any suitable color, can change along with the pH of user's skin change color takes place.Can use any suitable water soluble flavours, as the product of ARILYESSENCE production.For example, can comprise cherry flavor.

From the detailed description of figure below, can clearly find more advantage and feature:

Fig. 1 has described the cross section of treatment combination fabric, as is generally used for giving birth to paper handkerchief or disposable diaper, has shown at least at the combined fabric surface impregnation that contacts with the user the antibiotic and/or antifungal composition of the present invention;

Fig. 2 has described the part cross section that inner surface scribbles the health elastomeric glove of the antibiotic and/or antifungal composition of the present invention; And

Fig. 3 has described the device of the mixing and the magnetic processing present composition in the mode of chart.

The cross section of processed as shown in Figure 1 combined fabric 1, pad 2 and outer

fiber cover layer

3,4 in it has, as be generally used for sanitary napkin or the disposable diaper, be full of antibiotic and/or antifungal composition of the present invention on a surface 5 of the enclosing cover layer 3 that contacts with user's skin at least.

The part cross section of elastomeric glove 10 comprises elastic layer 11 as shown in Figure 2, for example is made of and coating 12 latex or ethene, and it contains antibiotic and/or antifungal composition of the present invention, is used as the coating of the inner surface 13 of emgloves 10.

Fig. 3 has illustrated the device 20 of the mixing and the magnetic processing present composition with way of illustration.This device comprises the mixing duct 21 that contains a tank 22, agitating device 23, visible axle 24 and the agitation blades 25 that drives by engine 26, visible heater 27 be resistance heater 28 (non-dimension scale) and in pipeline 21 heat insulation lid 29.Field generator for magnetic is usually at 30 places, its effective influence the magnetic field of composition in the tank.Shown in the middle chart of Fig. 3, field generator for magnetic 30 comprises and is twining conducting metal rod 33a respectively, the electric wire 32a of 33b, at least two electrodes 31 of the coiling coils tinplate of 32b (anode 31a and negative electrode 31b) and at least one are in current range more than 20 amperes, be enough to supply with two electrode 31a below 40 amperes, the dc source 34 of 31b.Two electrodes 31 are placed on the bridge 35, and the width of bridge and tank 22 are equal to, but with tank 22 electric insulations, tank 22 can be made with stainless steel.Tank 22 also has drainage pipeline 40 and valve 41.

The device of Fig. 3 can be used to implement the preparation method of the present composition.This method comprises successively provides the mixing duct 21 that comprises tank 22, the agitating device 23 in tank 22 and be positioned at effective field generator for magnetic 30 that influences tank 22 composition magnetic fields.Half is full of water mixing duct 21, and described water is heated to about 50 ℃.At least four kinds of active components of the present composition add in the water of mixing duct 21, slowly stir mixture before getting with low shearing flow.Preceding mixture is placed the field regions regular hour with magnetic field intensity, make the proportion of precursor increase to 1.018 by 1.015.Add remaining water generates treatment mixture.

Water should leave standstill for a moment earlier before heating.Preferably at least four kinds of active components slowly add in the water of mixing duct 21 successively, stir with low shearing flow with agitating device 23.

This method also is included in and adds at least a supplementary element in the treatment mixture, slowly mixes with low shearing flow.This at least a composition is preferably selected from thickener, wetting agent, and surfactant, the active ingredient of regulating smell, dyestuff and spices, the example will be discussed following.When at least two kinds of supplementary elements join in the treatment mixture, in the treatment mixture that it is added pipeline 21 before, this method can also comprise at least two kinds of supplementary elements of (not shown) mixed together in the pipeline of another separation earlier.

Approximately from 1 to the 60 minute time that preceding mixture is handled, be preferably 20 to 40 minutes in field region.

Pilot plant equipment

The mixing duct that uses is columniform, sees the description of Fig. 3, and diameter approximately is 6.5 feet, is 4 feet deeply.One batch of material is about 250 gallons, and approximately each batch adding can make the degree of depth of mixing duct reach about 3 feet for 250 gallons.Produce two electrodes in magnetic field, i.e. anode and negative electrode, spacing be approximately 6 feet.Stirring vane totally is approximately 6 feet long, places below the least significant end of two electrodes, and with 1.5 horsepowers, the motor driven of variable-ratio.

Each anode and negative electrode are made up by about 25 feet long current-carrying copper cash, and copper cash is roughly identical with the telephone wire thickness, is 3 feet along length, and diameter is that 1.15 inches rod iron twines.Copper cash twines at the mid portion of rod iron respectively.Does not twine at the two ends of rod iron, so that stay 6 inches respectively at the two ends of two rod irons.Copper cash twines successively, and that leans on is near more good more.

Utilize the DC voltage of 24 volts of field generator for magnetic, about 20 minutes time, provide about 30 amperes electric current in coil.These parameters are that embodiment provides, and are not limited thereto.Known to the technical staff who knows the field, magnetic field, the parameter of definition electrical domain comprises the length of electrode, and distance between them and the DC voltage of using may change in very wide scope.Similarly, define the parameter in field, magnetic field, comprise wire circle, the cross-sectional area of coil and the electric current of coil can change in very wide scope.

The color of mixture and proportion change in the magnetic treatment process, and are used for monitoring process.The color of mixture is water colour (water-white) when beginning, and becomes faint yellowly in the magnetic treatment process, shows that some have taken place changes, for example perhaps be four kinds of active components wherein form compound or complex between one or more.Electric current is lower than 20 ampere-hours, and seek out the color of expection and the change of proportion needs long time.40 amperes or higher electric current become the color of composition unexpected dark yellow brown.The proportion of the composition of process magnetic treatment increases in 1.015 to 1.018 scopes gradually.

In use in the trial work plant, field generator for magnetic produces the bigger magnetic field (in the z direction) with the electrode axis parallel.Between these magnetic field generating electrodes (anode and negative electrode), individual coil stacks up and formed very strong magnetic field along centering coil between anode and negative electrode.Offset by the opposing magnetic field of adjacent windings at the magnetic field of another one direction composition.Beyond field generator for magnetic because this cancellation effect, magnetic field very a little less than.For the long electrode of the length diameter group of magnetic field generating electrodes, its magnetic field approaches 0.

Though magnetic field is energy measurement not, the intensity in magnetic field can use ampere's rule to calculate.Ampere's rule relates to the circulation of multiply by the B of μ o (general formula 1) along loop to current density by the loop.This has produced magnetic field along center line between electrode.It should be noted that promptly by the electric current of sinusoidal variation, N/L is the amplitude (maximum) in magnetic field because current intensity changed along with the time, and Bo also is like this.Therefore, we also can be called the value of Bo mean square root (RMS), and BRMS=|Bo|/sqrt (general formula 2).

The time variation in magnetic field has also shown BRMS.Yet this can not tell people that what is electrode magnetic field in addition.In order to calculate it, need to use the Biot-Savart rule.All offset along axisymmetric all the magnetic field compositions of z-, have only the magnetic field composition of z direction to exist by current loop.Therefore, when the R=coil radius, satisfy So＜i at place, z position along electrode axis〉B＜/i〉(general formula 3).This general formula 3 shows works as z; During R, B is to being the effect of z.Attention descends rapidly along with z increases B.

Embodiment 1: glove coating composition (QUATROGLOVE) and method

Preparation is suitable for being used as the composition of the inboard dip-coating layer of elastomeric glove, and comprising following composition, its quantity is represented with described percentage by weight.

N-alkyl-dimethyl benzene-ammonium chloride of 0.5% (as the BARQUAT MB-50 of Lonza or the production of Pacific CoastChemicals company);

1.0% hexadecane sal-ammoniac Cetramonium Chloride (for example, the CARSOQUAT CT-429 that Lonza or Pacific Coast Chemicals company produce, hexadecane trimethyl sal-ammoniac);

1.0% hot benzene glycan-9;

0.2％Quaternium?22：

2.4% chlorhexidine gluconate (CHG, 4%)

0.1% cherry flavor;

30.0% dimethyl siloxane (a kind of silicone liquid);

2.0% Incroquat Benhenyl (tms); With

62.79% water (using deionized water or distilled water).

Only about half of water injects first mixing duct of pilot plant shown in Figure 3, leaves standstill for a moment, is heated to about 50 ℃.With N-alkyl-dimethyl benzene-ammonium chloride, the hexadecane sal-ammoniac, hot benzene glycan-9, Quaternium 22 and chlorhexidine gluconate slowly add in the hot water successively, stir with low shearing flow at leisure, produce first mixture.First mixture is placed the field regions regular hour with magnetic field intensity, make effective proportion increase to 1.018, promptly approximately need 20 to 30 minutes by 1.015 with first mixture.

It is light yellow that we see that the color of first mixture is become by water colour (water-white), and the inventor thinks that this may be owing to formed a kind of compound of gripping key altogether that has, and has therefore changed the color of composition.And this mixture is approximately 30 amperes at electric current, uses in 24 volts the field coil and handles.If electric current is lower than 20 amperes, described processing then requires unpractical, longer time to reach desirable rate of specific gravity.If electric current is increased to 40 amperes, the color of mixture becomes makes us uncomfortable dark yellow brown, for operation, may be no advantage to this based composition, this may be because, to small part because, due to the unexpected electrolysis of composition components.

Half remaining water is added in second mixing duct, and heats water to about 50 ℃.With cherry flavor, dimethyl siloxane (a kind of silicone liquid) and IncroquatBenhenyl (tms) join in second mixing duct and stir, and obtain proportion and be 0.87 second mixture.Second mixing duct is handled without the magnetic field treating apparatus.

Under low shearing flow stirred, second mixture slowly joined in first mixture of first mixing duct, generated to be suitable for preparing the internally coated composition of elastomeric glove.The pH value scope of said composition is between 5.5 to 7.0.Compare with water, the specific gravity range of composition is between 0.85 to 0.89.

A kind of latex composition is coated onto on the mould 50 ℃ the time, forms green emgloves.Still the green emgloves on mould immerses in the composition of the present invention and to form one deck coating, dries in temperature range is 110 to 120 ℃ hot-air channel.Gloves are removed from mould, and medial surface is routed up, and makes present composition composition coated on the inner surface of gloves.

Embodiment 2: glove coating composition (QUATR OGLOVE)

Preparation viscosity is the fluid composition of 800cps, and it comprises following four kinds of active components, represents with percentage by weight:

0.13% Quaternium 12 (scope of application 0.08-0.13%);

2.8% hexadecane trimethyl sal-ammoniac (scope of application 0.80-3.00%);

2.8% docosane trimethyl sal-ammoniac first sulphide and octadecanol (scope of application 2.20-3.00%); With

0.1% certain herbaceous plants with big flowers base pyridinium chloride father-in-law (scope of application 0.08-1.55%); They are mixed in device that embodiment 1 describes and magnetic field.

Said composition also is included in second mixing duct mixes, heating, join then in the aforementioned means mix and the active component of magnetic field processing in following composition:

(1) a kind of thickener comprises:

30.00% ring (two) methyl silicone (scope of application 27.20-33.80%);

0.70% ring (two) methyl silicone dimethiconol (useful scope 0.05-0.90%);

(2) a kind of wetting agent (scope of application 0.09-0.12%) that comprises 0.1% aloe extract;

(3) a kind of composition of removing peculiar smell wherein comprises the sodium salt (scope of application 1.00-2.50%) of at least a 1.0% organic sesquicarbonate; With

(4) a kind of indicator that detects described composition existence, it can be a kind of dyestuff, can be 0.0023% FC﹠amp; The red #28 (scope of application 0.0021-0.0024%) of C; And/or water soluble flavours, can be 0.01% cherry flavor (scope of application 0.01-0.012%).

Embodiment 3: liquid/colloidal compositions (QUATROGUARD)

Prepare a kind of proportion and be 1.01 fluid composition, it draws together water and following four kinds of active components, represents with percentage by weight:

1.2% hexadecane trimethyl sal-ammoniac (scope of application 0.80-1.30%);

Didecyl-alkyl dimethyl ammonium chloride of 0.3% (scope of application 0.15-0.35%);

0.1% Quaternium 22 (scope of application 0.08-1.55%); With

0.08% zephiran chloride (Benzalkonium chloride) (scope of application 0.07-0.13%).With they mixed processing 20 minutes in embodiment 1 described device and magnetic field.Then this mixture was left standstill 30 minutes.Restart to stir with low shearing flow, add following supplementary element again:

(1) thickener, it is 1.0% Natrosool HHR 250 (scope of application 0.002-1.50%); With

(2) a kind of wetting agent, it is 0.1% aloe extract (scope of application 0.09-0.12%).

Composition also is included in second mixing duct and mixes, heating, join then in the aforementioned means mix and the active component of magnetic treatment in:

(1) a kind of composition of removing peculiar smell wherein comprises the sodium salt (scope of application 1.00-2.50%) of at least a 2.50% organic sesquicarbonate; With

(2) a kind of water soluble flavours, it is 0.01% cherry flavor (scope of application 0.01-0.012%).

By changing the quantity of various compositions, especially thickener, said composition can be prepared into liquid or colloid shape, the person skilled in art knows this point.Said composition or any present composition can not make by magnetic treatment, and are used for described purpose.Yet the magnetic treatment of active component has significantly prolonged composition and has used the action time of bringing into play functional activity on the area at acceptors such as the mankind or animals, for example, and antibiotic or antifungal property.

Be appreciated that without departing from the scope and spirit of the present invention many other modifications all allow, those skilled in the art can finish the present invention.Therefore, here be not intended to additional claims are limited in the scope of specification, and wish claims are interpreted as comprising that the present invention has the feature of the new novelty of all patents that those skilled in the art regards these features as all features that belong to equivalent of the present invention.

Claims

1. aqueous composition with at least a antibiotic or antifungal property comprises:

The water of 85 weight % to 90 weight %; At least four kinds of active components comprise:

0.80 hexadecane trimethyl sal-ammoniac to 1.30 weight %;

0.07 at least a zephiran chloride and the grapefruit seed extract of being selected to 0.08 weight %;

0.15 didecyl-alkyl dimethyl ammonium chloride to 0.35 weight %; With

The Quaternium 22 of 0.08% to 1.55 weight %.

2. aqueous composition according to claim 1 further comprises a kind of thickener.

3. aqueous composition according to claim 2, wherein said thickener are to be selected from a kind of NATRASOOL HHR 250 and methylcellulose 40-401 at least, and its amount ranges is 0.09 to 1.20 weight %.

4. aqueous composition according to claim 1 further comprises a kind of wetting agent.

5. aqueous composition according to claim 4, wherein said wetting agent are to be selected from least a aloe extract, vitamin E, and citric acid and glycerine, its amount ranges is 0.09 to 0.12 weight %.

6. aqueous composition according to claim 1 further comprises a kind of active ingredient of regulating smell.

7. aqueous composition according to claim 6, wherein said active ingredient are the sodium salts of at least a organic sesquicarbonate, and its amount ranges is 1.00 to 2.50 weight %.

8. aqueous composition according to claim 1 further comprises at least a dyestuff or spices.

9. one kind is selected from diaper, and the hygiene tissue articles for use of sanitary napkin and paper handkerchief comprise:

A kind of combined fabric; With

A kind of aqueous composition, said composition comprises:

The water of 85 to 90 weight %; With

At least four kinds of active components comprise:

2.20 docosane trimethyl sal-ammoniac first sulphide and octadecanol to 3.00 weight %;

0.15 Quaternium 12 to 0.33 weight %;

0.80 hexadecane trimethyl sal-ammoniac to 3.00 weight %; With

0.08 hexadecylpyridinium chloride father-in-law to 1.55%.

10. hygiene tissue articles for use according to claim 9 further comprise a kind of thickener.

11. hygiene tissue articles for use according to claim 10, wherein said thickener comprises:

0.80 ring (two) methyl silicone to 1.20 weight %; With

0.05 ring (two) methyl silicone dimethiconol to 0.90 weight %.

12. hygiene tissue articles for use according to claim 9 further comprise a kind of wetting agent.

13. hygiene tissue articles for use according to claim 12, wherein said wetting agent are at least a aloe extracts that is selected from, vitamin E and citric acid, and its amount ranges is percentage 0.09 to 0.12 weight %.

14. hygiene tissue articles for use according to claim 9 further comprise a kind of active ingredient of regulating smell.

15. hygiene tissue articles for use according to claim 14, wherein said active ingredient are the sodium salts of at least a organic sesquicarbonate, its amount ranges is 1.00 to about 2.50 weight %.

16. hygiene tissue articles for use according to claim 9 further comprise dyestuff or the spices of at least a 0.0021 to 0.0024 weight %.

17. a sanitary glove comprises:

The gloves that constitute by elastomeric material; With

At least the coating that has in the inner surface portion of gloves, this coating comprise the aqueous composition with at least a antibiotic and antifungal property, and comprise:

The water of 85 to 90 weight %; With

At least four kinds of active components comprise:

0.15 Quaternium 12 to 0.33 weight %;

0.80 hexadecane trimethyl sal-ammoniac to 3.00 weight %; With

0.08 hexadecylpyridinium chloride father-in-law to 1.55 weight %.

18. sanitary glove according to claim 17, wherein said aqueous composition further comprises thickener.

19. sanitary glove according to claim 18, thickener wherein comprises:

0.80 hexadecane trimethyl sal-ammoniac to 1.20 weight %; With

0.05 ring (two) methyl silicone dimethiconol to 0.90 weight %.

20. sanitary glove according to claim 17, wherein said aqueous composition further comprises a kind of wetting agent.

21. sanitary glove according to claim 20, wherein said wetting agent are to be selected from aloe extract and vitamin E at least, its amount ranges is 0.09 to 0.12 weight %.

22. sanitary glove according to claim 17, wherein said aqueous composition further comprise a kind of active ingredient of regulating fragrance.

23. sanitary glove according to claim 22, wherein said active ingredient are the sodium salts of at least a organic sesquicarbonate, its amount ranges is 1.00 to 2.50 weight %.

24. sanitary glove according to claim 17, wherein said aqueous composition further comprise dyestuff or the spices of at least a 0.0021 to 0.0024 weight %.

25. sanitary glove according to claim 17, elastomeric material wherein are a kind of latex or vinyl.

26. the described method for compositions of preparation claim 1 comprises successively:

The mixing duct that comprises tank is provided, is positioned at the agitating device of tank and is positioned at effective field generator for magnetic that influences tank composition magnetic field;

The water that mixing duct is added half;

Heat water to about 50 ℃;

In the water at least four kinds of active components adding mixing ducts;

Slowly stir mixture before producing with low shearing flow;

Preceding mixture is placed the field regions regular hour with magnetic intensity, can make the proportion of precursor increase to 1.018 effectively by 1.015; And

Add the mixture after remaining water generates processing.

27. method according to claim 26, wherein said field generator for magnetic comprise at least two electrodes of rewiring plate around coils tinplate; With at least one current range that is enough to supply with two electrodes more than 20 amperes, the dc source below 40 amperes.

28. method according to claim 26 leaves standstill water before further being included in heating; Successively at least four kinds of active components are added in the water of mixing duct with low shearing flow at leisure.

29. method according to claim 26 further comprises in handling the back mixture adding at least a supplementary element, slowly mixes with low shearing flow.

30. method according to claim 29, wherein at least a composition is selected from thickener, wetting agent, and surfactant is effectively regulated composition, dyestuff and the spices of smell.

31. method according to claim 29, wherein at least two kinds of supplementary elements are joined in the mixture of processing back, this method further is included in before its adding processing back mixture, with at least two kinds of supplementary elements mixed together in pipeline of a separation.

32. method according to claim 26, the time that wherein said preceding mixture is handled in field region is 1 to 60 minute.

33. method according to claim 32, the time that wherein said preceding mixture is handled in field region is 20 to 40 minutes.