CN1327828A - Adhesive bandage able to relieve inflammation, astringe and grow muscle and its preparing process - Google Patents
Adhesive bandage able to relieve inflammation, astringe and grow muscle and its preparing process Download PDFInfo
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- CN1327828A CN1327828A CN 01113421 CN01113421A CN1327828A CN 1327828 A CN1327828 A CN 1327828A CN 01113421 CN01113421 CN 01113421 CN 01113421 A CN01113421 A CN 01113421A CN 1327828 A CN1327828 A CN 1327828A
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- radix
- wound
- radix angelicae
- card
- chinensis
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Abstract
An adhesive bandage for relieving inflammation, astringing and promoting granulation is prepared from beta-glucosan and 9 Chinese-medicinal materials including pubescent angelica root, red peony root, dahurian angelica root, borneol, etc. through coating on substrate. Its advantages include high curative effect and high penetrability, air permeability and adhesion.
Description
The present invention relates to a kind of wound can be obedient, and particularly a kind of wound with multiple efficacies such as antiinflammatory, convergence and granulation promotings can be obedient, and this wound can obedient manufacture method.
Wound can card be a kind of use medical devices very easily.At present, domestic wound is can obedient kind a lot, can card as sticking plaster cloth, " Bandaid " wound etc.But can there be the various remarkable defective in these wounds by card: effect is single, does not possess the effect of antiinflammatory, convergence and granulation promoting simultaneously, though the function that antiinflammatory is arranged that has, can be obedient as " Bandaid " wound, but it is slow to take effect, and sticking card is poor, breathability is poor, simultaneously skin is had certain zest.Chinese patent 91217345.3 disclose a kind of PVP-of having iodine wound can the card, though have certain antiinflammatory and anastalsis, effect is unsatisfactory, and the effect of misconvergence and granulation promoting.
Therefore, providing a kind of wound that has various effects such as antiinflammatory, convergence and granulation promoting simultaneously can card, be that people institute is very expected.
The object of the present invention is to provide that a kind of pollution-free, viscosity is strong, good permeability, instant effect, and can use repeatedly for several times, and have antiinflammatory simultaneously, hold back skin ulcer, the wound of effect such as granulation promoting can card, with overcome the existing in prior technology effect single, take effect that slow, sticking card is poor, breathability difference and to skin defective excitatory.
Another object of the present invention is to provide the manufacture method that above-mentioned wound can card.
The object of the present invention is achieved like this:
The present invention's wound can be made of substrate and the active component of coating on the substrate by card.
Said substrate is a kind of carrier, can adopt multiple material, as macromolecular material, gauze or gummed paper etc.;
The present invention is a starting point with the immune system and the physiological function of transfer and human activin self, the principle that utilization Chinese herbal medicine the monarch and his subjects are auxilliary mutually, adopt Cortex cercis chinensis, Radix Angelicae Pubescentis, Radix Paeoniae Rubra, the Radix Angelicae Dahuricae, Borneolum Syntheticum, the Radix Astragali, Galla Chinensis, Radix Arnebiae (Radix Lithospermi), catechu and beta glucan etc. as active component, both controlled table, effected a permanent cure again.The essence of Cortex cercis chinensis chain timbers can be pursued blood by dispelling the stagnated QI; The essence of Radix Angelicae Pubescentis system soil can rise gas and invigorate blood circulation, and pulls out cold poison in the bone, removes the muscle being attacked by dampness; The essence of Radix Paeoniae Rubra system fire, the energy relieving pain and activating blood circulation, hemopoietic removes wind; The Radix Angelicae Dahuricae is Jin Zhijing, can go insertion tendon pain humorously.Flesh is living, and then meat is not dead, and blood is lived then through ruton.The pain relieving of Borneolum Syntheticum clearing heat for detumescence, Radix Astragali tonifying Qi and lifting yang, expelling pus and promoting granulation; The detumescence of Galla Chinensis Jie poison, removing dampness is held back skin ulcer; Radix Arnebiae (Radix Lithospermi) Jie poison is held back skin ulcer; The catechu removing dampness is held back the skin ulcer hemostasis; Beta glucan all has inhibitory action to various pathogens and fungus, promotes wound healing.
The wound of said medicine preparation can be obedient, not only can bring into play functions peculiar separately, and can have synergism, can have antiinflammatory simultaneously, hold back skin ulcer, function such as granulation promoting, to eczema, zona shingles, skin injury, local trace, tissue necrosis, post surgery treatment, skin furuncle and phyma, the hemorrhoid etc. of bursting all have significant curative effect.
The composition and the parts by weight of said active component comprise:
Cortex cercis chinensis 30～90
Radix Angelicae Pubescentis 20～45
Radix Paeoniae Rubra 15～28
The Radix Angelicae Dahuricae 7.5～12
Borneolum Syntheticum 3～8
The Radix Astragali 15～24
Galla Chinensis 10～25
Beta glucan 13～17
Preferred ratio is:
Cortex cercis chinensis 80～70
Radix Angelicae Pubescentis 30～40
Radix Paeoniae Rubra 19～25
The Radix Angelicae Dahuricae 9～10
Borneolum Syntheticum 5～6.5
The Radix Astragali 18～21
Galla Chinensis 15～20
Beta glucan 14～16
According to the present invention, also can add an amount of Radix Arnebiae (Radix Lithospermi), catechu and an amount of surfactant in the above-mentioned active component, preferred surfactants is non-ionic surface active agent and anion surfactant, as polyethers, Dexol, Tween 80, methylcellulose etc., Action of Surfactant is that various medicines are disperseed, in order to avoid reunite.
In above-mentioned prescription, Cortex cercis chinensis, Radix Angelicae Pubescentis, Radix Paeoniae Rubra, the Radix Angelicae Dahuricae, Borneolum Syntheticum, the Radix Astragali and Galla Chinensis are general Chinese herbal medicine, beta glucan can adopt document, and (International Journal of Cancer.Infec.Immuno.1985.20,804-410) disclosed method is prepared.
Antiinflammatory of the present invention, to hold back skin ulcer, granulation promoting adhesive bandage be to make like this:
Cortex cercis chinensis processed with wine, Radix Angelicae Pubescentis parch, Radix Paeoniae Rubra vinegar system are sneaked into according to dosage the Radix Angelicae Dahuricae, Borneolum Syntheticum, the Radix Astragali, Galla Chinensis, beta glucan, in an amount of Radix Arnebiae (Radix Lithospermi), the catechu.The method that above-mentioned each medicine adopts classification to morcel, its fineness is all about 200～400 orders.Powder after pulverizing is added an amount of surfactant, mix mixedly, adopt the evenly coating on substrate of persons skilled in the art known method, carry by required size again and cut, promptly get antiinflammatory, hold back skin ulcer, granulation promoting is created can be obedient.
Term processed with wine, parch and vinegar are made as a kind of manufacture method of Chinese herbal medicine of routine, and this method is existing detailed introduction in " quality of Chinese medicine and rational Application thereof " (Jiangsu science tech publishing house) book.
Adhesive bandage of the present invention is soft smooth, and property of medicine permeability is strong, and adhesion is strong, good permeability, and can repeatedly use repeatedly, prove through clinical trial, effects such as this adhesive bandage has very good antiinflammatory, holds back skin ulcer, granulation promoting are that a kind of very promising pure natural medical wound can card.
Using method is as follows:
At first affected part is carried out debridement, remove slough and then this adhesive bandage is affixed on the wound surface.At the treatment initial stage, if wound exudate is more, dressing is soaked into by sepage and promptly gives replacing.Sepage promptly obviously reduces after about three days, changes dressings every day once, and wound surface can be grown flat healing gradually after two weeks.
Below will be described in detail preparation of the present invention and curative effect by embodiment.
Embodiment 1
Get 3 gram Cortex cercis chinensis processed with wine, 2 gram Radix Angelicae Pubescentis parches, 1.5 gram Radix Paeoniae Rubra vinegar systems, the 0.75 gram Radix Angelicae Dahuricae, 0.3 gram Borneolum Syntheticum, the 1.5 gram Radixs Astragali, 1 gram Galla Chinensis, 1.3 gram beta glucans, 1.2 gram Radix Arnebiae (Radix Lithospermi) and 0.3 gram catechu, mix homogeneously, the method that adopts classification to morcel, it is about 300 orders that above-mentioned each medicated powder is broken to fineness.Powder after pulverizing is added 0.01 gram methylcellulose, mix mixedly, coat on the porous polyethylene film, carry by required size again and cut, promptly get antiinflammatory, hold back skin ulcer, granulation promoting is created can be obedient.
Embodiment 2
Get 9 gram Cortex cercis chinensis processed with wine, 4.5 gram Radix Angelicae Pubescentis parches, 2.8 gram Radix Paeoniae Rubra vinegar systems, the 1.2 gram Radixs Angelicae Dahuricae, 0.8 gram Borneolum Syntheticum, the 2.4 gram Radixs Astragali, 2.5 gram Galla Chinensiss, 1.7 gram beta glucans, 1.6 gram Radix Arnebiae (Radix Lithospermi) and 0.8 gram catechu, mix homogeneously, the method that adopts classification to morcel, it is about 300 orders that above-mentioned each medicated powder is broken to fineness.Powder after pulverizing is added 0.1 gram Tween 80, mix mixedly, coat on the non-woven fabrics, carry by required size again and cut, promptly get antiinflammatory, hold back skin ulcer, granulation promoting is created can be obedient.
Embodiment 3～9
Adopting the method identical with embodiment 1 to prepare wound of the present invention can be obedient, and the proportioning of various medicines is as follows:
Embodiment 10
| Example 3 | Example 4 | Example 5 | Example 6 | Example 7 | Example 8 | Example 9 | |
| Cortex cercis chinensis | ?3.75 | ?4.5 | ?5.25 | ?6 | ?6.75 | ?7.5 | ?8.25 |
| Radix Angelicae Pubescentis | ?2.4 | ?2.7 | ?3 | ?3.3 | ?3.6 | ?3.9 | ?4.2 |
| Radix Paeoniae Rubra | ?1.65 | ?1.8 | ?1.95 | ?2.1 | ?2.25 | ?2.4 | ?2.6 |
| The Radix Angelicae Dahuricae | ?0.8 | ?0.85 | ?0.9 | ?0.96 | ?1.02 | ?1.08 | ?1.14 |
| Borneolum Syntheticum | ?0.36 | ?0.43 | ?0.5 | ?0.56 | ?0.62 | ?0.68 | ?0.74 |
| The Radix Astragali | ?1.6 | ?1.7 | ?1.8 | ?1.9 | ?2.0 | ?2.15 | ?2.3 |
| Galla Chinensis | ?1.15 | ?1.3 | ?1.5 | ?1.7 | ?1.9 | ?2.1 | ?2.3 |
| Beta glucan | ?1.35 | ?1.4 | ?1.45 | ?1.5 | ?1.55 | ?1.6 | ?1.65 |
| Radix Arnebiae (Radix Lithospermi) | ?1.25 | ?1.3 | ?1.35 | ?1.4 | ?1.45 | ?1.5 | ?1.55 |
| Catechu | ?0.36 | ?0.43 | ?0.5 | ?0.56 | ?0.62 | ?0.68 | ?0.74 |
| Dexol | ?0.03 | ?0.04 | ?0.05 | ?0.06 | ?0.07 | ?0.08 | ?0.09 |
90 years old stroke patients have 10 years bed histories approximately, the right buttocks trace 8cm that bursts, and dark 4cm through debridement, removes slough, and advises families of patients to reduce the compressing trace position of bursting.Adopt the wound of embodiment 4 can card, every day secondary, after the week, routed trace heals gradually, after two weeks, forms new epithelial tissue, scar is recovered normally and not to stay in the back.
Embodiment 11
The lasting routed trace of shank: one 53 years old male patient, shank continues the trace of bursting, and area is 3.8cm * 1.9cm, and through removing slough, the wound of employing embodiment 1 can be obedient, and after 10 days, wound all heals.
Embodiment 12
One athletic injury causes varicosis, and vasculitis causes the patient that bursts, and after the wound of employing embodiment 2 can obediently be treated, wound is i.e. healing in two weeks.
Embodiment 13
Routed trace area reaches 10cm * 9cm to one patient because of traffic accident causes, and causes exposure of lower limb tissue and tissue necrosis, and through clear skin ulcer, the wound of employing embodiment 6 promptly grew new epithelial tissue and granulation in 10 days after can obediently treating, and routed trace heals gradually, and the trace face of bursting is reduced into 8cm * 7cm.
Embodiment 14
Banded cicatrix: treat example surplus the banded cicatrix 30 with the adhesive bandage of embodiment 2,3-4 days alleviation of pain were formed a scab and are healed preventing from scar in 6-7 days.
Embodiment 15
The yellow fluid scar: use the disinfectant washout earlier, remove dense crust, the adhesive bandage with embodiment 7 is affixed on the affected part then, treatment primary disease 13 examples, and fast person two days, slow person was promptly healed in four days.
Claims (7)
1. an antiinflammatory, convergence, granulation promoting wound can cards, are made of substrate and the active component coated on the substrate, it is characterized in that the composition and the parts by weight of said active component comprise:
Cortex cercis chinensis 30～90
Radix Angelicae Pubescentis 20～45
Radix Paeoniae Rubra 15～28
The Radix Angelicae Dahuricae 7.5～12
Borneolum Syntheticum 3～8
The Radix Astragali 15～24
Galla Chinensis 10～25
Beta glucan 13～17
2. wound as claimed in claim 1 can be obedient, it is characterized in that the composition and the parts by weight of active component comprise:
Cortex cercis chinensis 80～70
Radix Angelicae Pubescentis 30～40
Radix Paeoniae Rubra 19～25
The Radix Angelicae Dahuricae 9～10
Borneolum Syntheticum 5～6.5
The Radix Astragali 18～21
Galla Chinensis 15～20
Beta glucan 14～16
3. wound as claimed in claim 1 or 2 can the card, it is characterized in that, also can add an amount of Radix Arnebiae (Radix Lithospermi) in the active component or/and catechu or/and surfactant.
4. wound as claimed in claim 3 can be obedient, it is characterized in that surfactant is non-ionic surface active agent and anion surfactant.
5. wound as claimed in claim 4 can be obedient, it is characterized in that surfactant is polyethers, Dexol, Tween 80 or methylcellulose.
6. wound as claimed in claim 1 or 2 can the card preparation method, it is characterized in that, proportionally, Cortex cercis chinensis processed with wine, Radix Angelicae Pubescentis parch, Radix Paeoniae Rubra vinegar system, the Radix Angelicae Dahuricae, Borneolum Syntheticum, the Radix Astragali, Galla Chinensis and beta glucan are mixed, mix mixed after the pulverizing, coat on the substrate, promptly get antiinflammatory, hold back skin ulcer, the granulation promoting wound can card.
7. wound as claimed in claim 3 can the card preparation method, it is characterized in that, proportionally, with Cortex cercis chinensis processed with wine, Radix Angelicae Pubescentis parch, Radix Paeoniae Rubra vinegar system, the Radix Angelicae Dahuricae, Borneolum Syntheticum, the Radix Astragali, Galla Chinensis, beta glucan, an amount of Radix Arnebiae (Radix Lithospermi) or/and catechu or/and an amount of surfactant, pulverizing is mixed mixed, coat on the substrate, promptly get antiinflammatory, hold back skin ulcer, the granulation promoting wound can card.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 01113421 CN1327828A (en) | 2001-06-12 | 2001-06-12 | Adhesive bandage able to relieve inflammation, astringe and grow muscle and its preparing process |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 01113421 CN1327828A (en) | 2001-06-12 | 2001-06-12 | Adhesive bandage able to relieve inflammation, astringe and grow muscle and its preparing process |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1327828A true CN1327828A (en) | 2001-12-26 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 01113421 Pending CN1327828A (en) | 2001-06-12 | 2001-06-12 | Adhesive bandage able to relieve inflammation, astringe and grow muscle and its preparing process |
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Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101982169A (en) * | 2010-10-21 | 2011-03-02 | 王志钢 | Novel external non-plaster patch |
| CN102273380A (en) * | 2011-06-07 | 2011-12-14 | 汪盛明 | Grafting paste and preparation method thereof |
| CN101584877B (en) * | 2009-06-15 | 2012-11-21 | 于向英 | Packed medicament plaster for laparoscopic surgery |
| CN103181964A (en) * | 2013-03-21 | 2013-07-03 | 姜凤丽 | Traditional Chinese medicine composition for treating animal body surface injuries and preparation method thereof |
| CN103584950A (en) * | 2013-12-02 | 2014-02-19 | 浙江海洋学院 | Method for preparing pearl powder adhesive bandage |
| CN104116871A (en) * | 2014-08-11 | 2014-10-29 | 周盈裕 | Traditional Chinese medicine paste for treating ulcers |
| CN104288829A (en) * | 2014-09-29 | 2015-01-21 | 江苏奇力康皮肤药业有限公司 | Adhesive bandage and preparation method thereof |
| CN106075120A (en) * | 2016-07-01 | 2016-11-09 | 宁波希诺亚海洋生物科技有限公司 | A kind of Eczema Creams agent |
| CN111202821A (en) * | 2020-03-26 | 2020-05-29 | 齐鲁工业大学 | Traditional Chinese medicine extract with allergy-relieving and anti-inflammatory effects as well as preparation method and application thereof |
-
2001
- 2001-06-12 CN CN 01113421 patent/CN1327828A/en active Pending
Cited By (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101584877B (en) * | 2009-06-15 | 2012-11-21 | 于向英 | Packed medicament plaster for laparoscopic surgery |
| CN101982169A (en) * | 2010-10-21 | 2011-03-02 | 王志钢 | Novel external non-plaster patch |
| CN102273380A (en) * | 2011-06-07 | 2011-12-14 | 汪盛明 | Grafting paste and preparation method thereof |
| CN102273380B (en) * | 2011-06-07 | 2012-11-21 | 汪盛明 | Grafting paste and preparation method thereof |
| CN103181964B (en) * | 2013-03-21 | 2014-10-29 | 姜凤丽 | Traditional Chinese medicine composition for treating animal body surface injuries and preparation method thereof |
| CN103181964A (en) * | 2013-03-21 | 2013-07-03 | 姜凤丽 | Traditional Chinese medicine composition for treating animal body surface injuries and preparation method thereof |
| CN103584950B (en) * | 2013-12-02 | 2015-07-08 | 浙江海洋学院 | Method for preparing pearl powder adhesive bandage |
| CN103584950A (en) * | 2013-12-02 | 2014-02-19 | 浙江海洋学院 | Method for preparing pearl powder adhesive bandage |
| CN104116871A (en) * | 2014-08-11 | 2014-10-29 | 周盈裕 | Traditional Chinese medicine paste for treating ulcers |
| CN104288829A (en) * | 2014-09-29 | 2015-01-21 | 江苏奇力康皮肤药业有限公司 | Adhesive bandage and preparation method thereof |
| CN104288829B (en) * | 2014-09-29 | 2016-02-24 | 江苏奇力康皮肤药业有限公司 | A kind of adhesive bandage and preparation method thereof |
| CN106075120A (en) * | 2016-07-01 | 2016-11-09 | 宁波希诺亚海洋生物科技有限公司 | A kind of Eczema Creams agent |
| CN106075120B (en) * | 2016-07-01 | 2019-09-20 | 宁波希诺亚海洋生物科技有限公司 | A kind of Eczema Creams agent |
| CN111202821A (en) * | 2020-03-26 | 2020-05-29 | 齐鲁工业大学 | Traditional Chinese medicine extract with allergy-relieving and anti-inflammatory effects as well as preparation method and application thereof |
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