CN103584950A - Method for preparing pearl powder adhesive bandage - Google Patents

Method for preparing pearl powder adhesive bandage Download PDF

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Publication number
CN103584950A
CN103584950A CN201310635082.2A CN201310635082A CN103584950A CN 103584950 A CN103584950 A CN 103584950A CN 201310635082 A CN201310635082 A CN 201310635082A CN 103584950 A CN103584950 A CN 103584950A
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Prior art keywords
adhesive bandage
substrate
margarita powder
preparation
medicine
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CN201310635082.2A
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CN103584950B (en
Inventor
郭健
王雅颖
宋文东
纪丽丽
韩丝银
王亚宁
应知伟
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Zhejiang Ocean University ZJOU
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Zhejiang Ocean University ZJOU
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00Bandages or dressings; Absorbent pads
    • A61F13/02Adhesive bandages or dressings
    • A61F13/0276Apparatus or processes for manufacturing adhesive dressings or bandages
    • A61F13/0289Apparatus or processes for manufacturing adhesive dressings or bandages manufacturing of adhesive dressings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42Use of materials characterised by their function or physical properties
    • A61L15/44Medicaments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00Bandages or dressings; Absorbent pads
    • A61F13/02Adhesive bandages or dressings
    • A61F13/0276Apparatus or processes for manufacturing adhesive dressings or bandages
    • A61F2013/0296Apparatus or processes for manufacturing adhesive dressings or bandages for making transdermal patches (chemical processes excluded)

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Manufacturing & Machinery (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Materials Engineering (AREA)
  • Epidemiology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention relates to a method for preparing a pearl powder adhesive bandage. The method sequentially includes the following steps that (1) pearl powder, auxiliary herb medicines and natural synergists are taken as raw materials, the pearl powder is ground, the auxiliary herb medicines are smashed, then the ground pearl powder and the smashed auxiliary herb medicines are mixed with the natural synergists, and water is added, so that the mixture is pulpy; (2) a porous polyethylene film or a non-woven fabric serves as a substrate, the substrate is cut to be oval, and the central area of the substrate is coated with adhesives; (3) the pulpy medicine obtained in the step (1) is made to be rectangular, solvents are volatilized through drying, then the pulpy medicine is attached to the substrate with the adhesives, and ultimately, release paper or films are placed on the rectangular medicine. The adhesive bandage is soft and smooth in hand feeling, the permeability of the medicine is high, the breathability is good, bleeding stopping and heating are quick to achieve, and as is proved in clinical experiments, the adhesive bandage has ideal functions on diminishing inflammation, stopping bleeding, diminishing swelling, healing sores, engendering flesh and the like.

Description

The preparation method of Margarita powder adhesive bandage
Technical field
The present invention relates to a kind of Margarita powder adhesive bandage, relate to especially a kind of adhesive bandage with anti-inflammation hemostasia, convergence granulation promoting function and medical value, and the preparation method of this adhesive bandage.
Background technology
Adhesive bandage is a kind of very extensive and convenient curable product that uses in daily life.The kind of adhesive bandage is a lot of in the market, but the effect that skin ulcer is protected in existing most of adhesive bandage hemostasis is also not obvious, can not meet the requirement of the simple and efficient healing of wound of people.As Chinese patent 02117251.X discloses a kind of flexible fabric bandage with Chinese medicine, although have certain anti-inflammatory analgetic effect, effect is unsatisfactory, and it is slow to take effect; Patent 201210583344.0 discloses a kind of Chinese herbal medicine adhesive bandage, though Chinese herbal medicine has certain hemostasia and dissipation blood stasis effect, but it is slow to take effect, and need use for a long time.
Summary of the invention
The object of this invention is to provide a kind of instant effect, permeability good, there is excellent air permeability and adhesion property, and the Margarita powder adhesive bandage simultaneously with functions such as hemostasia and detumescence, eliminating inflammation and expelling toxin, convergence granulation promotings, the wound of skin, eczema chickenpox, injury from falling down, post surgery treatment, carbuncle furunculosis, congestion and swelling pain etc. are all had to significant curative effect, to overcome the defect of the aspects such as existing slow, the function singleness of taking effect of existing adhesive bandage.
The technical solution adopted for the present invention to solve the technical problems is:
The preparation method of Margarita powder adhesive bandage, is characterized in that in turn including the following steps: the (1) preparation of adhesive bandage medicine, the (2) preparation of adhesive bandage substrate, the (3) shaping of adhesive bandage.
As the further optimization to technique scheme, wherein
(1) step comprises: using Margarita powder, auxiliary medicinal herbs and natural synergic agent is raw material, and Margarita powder is ground, and adjuvant grass meal is broken, then mixes with natural synergic agent, adds water furnishing pasty state;
(2) step comprises: adopting polyethylene film or the non-woven fabrics of porous is substrate, substrate is cut into ellipse, and coats adhesive agent in central area;
(3) step comprises: the pasty medicament that (1) step is prepared is made oblong-shaped, and drying vapors away solvent, sticks in the substrate that scribbles adhesive agent, finally on rectangle medicine, puts release paper or film.
As the further optimization to technique scheme, step (1) in, described Margarita powder is micro-nano sea water pearls powder or micro-nano mussel pearl powder, granularity is 100-500nm; Described auxiliary medicinal herbs are a kind of or any multiple combination in Radix Paeoniae Rubra, Herba Portulacae, Flos Lonicerae, Herba Taraxaci, Herba Violae, Flos Chrysanthemi Indici, Radix Angelicae Pubescentis and Ramulus Mori; Described natural synergic agent is a kind of or any multiple combination in beta glucan, sorbitan fatty acid ester, sucrose fatty acid ester and tea saponin.
As the further optimization to technique scheme, step (1) in, described auxiliary medicinal herbs are the combination of Radix Paeoniae Rubra, Flos Lonicerae, Radix Angelicae Pubescentis, described natural synergic agent is beta glucan, each components by weight is: Margarita powder 70%-90%; Radix Paeoniae Rubra 2%-5%; Flos Lonicerae 2%-3%; Radix Angelicae Pubescentis 2%-3%; Beta glucan 2%-10%; Distilled water 2%-9%.
As the further optimization to technique scheme, step (2) in, described substrate is cut into semi-major axis 2.5cm, the ellipse of semi-minor axis 1cm.
Adhesive bandage of the present invention is soft smooth, and the permeability of medicine is strong, and good air permeability, and arresting bleeding and healing the wound is fast, through clinical trial, proves, the effects such as the anti-inflammation hemostasia of this adhesive bandage, detumescence sore, convergence granulation promoting are quite desirable.
Below in conjunction with embodiment, the present invention is further described.
The specific embodiment
In the present invention, Margarita powder, Radix Angelicae Pubescentis, Radix Paeoniae Rubra, Flos Lonicerae are conventional Chinese herbal medicine, and beta glucan can adopt the disclosed method of document (International Journal of Cancer.Infec.Immuno.1985.20,804-810) to be prepared.
The manufacture method of the Chinese herbal medicine that term processed with wine, parch are a kind of routine, the method also has detailed introduction in the quality of < < Chinese medicine and in rationally applying > > (Jiangsu science tech publishing house) book.
Embodiment mono-:
Get 8.5 grams of Margarita powder, 0.2 gram of Radix Paeoniae Rubra processed with wine, 0.25 gram of Radix Angelicae Pubescentis parch, 0.25 gram of Flos Lonicerae, 0.6 gram of beta glucan, adopt the method for stage reduction, above-mentioned each medicine is crushed to granularity 300 order left and right, powder after pulverizing is added to 0.2 gram of distilled water furnishing pasty state, and mix homogeneously, coats on non-woven fabrics, by required size, carry out cutting again, obtain anti-inflammation hemostasia, convergence granulation promoting, detumescence treatment skin ulcer adhesive bandage.
Margarita powder adhesive bandage is to hemostasis, pain relieving, antiinflammatory, the skin ulcer cardinal symptom observation of curative effect result table of healing
Figure BDA0000427716380000031
Embodiment bis-:
Get 17 grams of Margarita powder, 0.4 gram of Radix Paeoniae Rubra processed with wine, 0.5 gram of Radix Angelicae Pubescentis parch, 0.5 gram of Flos Lonicerae, 1.1 grams of beta glucans, adopt the method for stage reduction, above-mentioned each medicine is crushed to granularity 300 order left and right, powder after pulverizing is added to 0.4 gram of distilled water furnishing pasty state, and mix homogeneously, coats on the polyethylene film of porous, by required size, carry out cutting again, obtain anti-inflammation hemostasia, convergence granulation promoting, detumescence treatment skin ulcer adhesive bandage.
Margarita powder adhesive bandage is to hemostasis, pain relieving, antiinflammatory, the skin ulcer cardinal symptom observation of curative effect result table of healing
Figure BDA0000427716380000041
Embodiment tri-:
Get 9 grams of Margarita powder, 0.3 gram of Radix Paeoniae Rubra processed with wine, 0.25 gram of Radix Angelicae Pubescentis parch, 0.25 gram of Flos Lonicerae, 0.6 gram of beta glucan, adopt the method for stage reduction, above-mentioned each medicine is crushed to granularity 300 order left and right, powder after pulverizing is added to 0.3 gram of distilled water furnishing pasty state, and mix homogeneously, coats on non-woven fabrics, by required size, carry out cutting again, obtain anti-inflammation hemostasia, convergence granulation promoting, detumescence treatment skin ulcer adhesive bandage.
Margarita powder adhesive bandage is to hemostasis, pain relieving, antiinflammatory, the skin ulcer cardinal symptom observation of curative effect result table of healing
Figure BDA0000427716380000042
More than describe preferred embodiment of the present invention in detail.Should be appreciated that those of ordinary skill in the art just can design according to the present invention make many modifications and variations without creative work.Therefore, all technical staff in the art on the basis of existing technology by the available technical scheme of logical analysis, reasoning, or a limited experiment, all should fall within the scope of protection of the present invention under this invention's idea.

Claims (5)

1. the preparation method of Margarita powder adhesive bandage, is characterized in that in turn including the following steps: the (1) preparation of adhesive bandage medicine, the (2) preparation of adhesive bandage substrate, the (3) shaping of adhesive bandage.
2. the preparation method of Margarita powder adhesive bandage according to claim 1, is characterized in that wherein
(1) step comprises: using Margarita powder, auxiliary medicinal herbs and natural synergic agent is raw material, and Margarita powder is ground, and adjuvant grass meal is broken, then mixes with natural synergic agent, adds water furnishing pasty state;
(2) step comprises: adopting polyethylene film or the non-woven fabrics of porous is substrate, substrate is cut into ellipse, and coats adhesive agent in central area;
(3) step comprises: the pasty medicament that (1) step is prepared is made oblong-shaped, and drying vapors away solvent, sticks in the substrate that scribbles adhesive agent, finally on rectangle medicine, puts release paper or film.
3. the preparation method of Margarita powder adhesive bandage according to claim 2, is characterized in that step (1), and described Margarita powder is micro-nano sea water pearls powder or micro-nano mussel pearl powder, and granularity is 100-500nm; Described auxiliary medicinal herbs are a kind of or any multiple combination in Radix Paeoniae Rubra, Herba Portulacae, Flos Lonicerae, Herba Taraxaci, Herba Violae, Flos Chrysanthemi Indici, Radix Angelicae Pubescentis and Ramulus Mori; Described natural synergic agent is a kind of or any multiple combination in beta glucan, sorbitan fatty acid ester, sucrose fatty acid ester and tea saponin.
4. the preparation method of Margarita powder adhesive bandage according to claim 3, in it is characterized in that step (1), described auxiliary medicinal herbs are the combination of Radix Paeoniae Rubra, Flos Lonicerae, Radix Angelicae Pubescentis, and described natural synergic agent is beta glucan, and each components by weight is: Margarita powder 70%-90%; Radix Paeoniae Rubra 2%-5%; Flos Lonicerae 2%-3%; Radix Angelicae Pubescentis 2%-3%; Beta glucan 2%-10%; Distilled water 2%-9%.
5. the preparation method of Margarita powder adhesive bandage according to claim 2, is characterized in that step (2), and described substrate is cut into semi-major axis 2.5cm, the ellipse of semi-minor axis 1cm.
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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104027200A (en) * 2014-03-20 2014-09-10 周义福 Preparation method of ginger powder band-aids
CN104288355A (en) * 2014-08-30 2015-01-21 彭殿英 Traditional Chinese medicine for treating furuncles
CN105797199A (en) * 2016-04-07 2016-07-27 杨兰 Band-aid containing pu'er tea extract
CN106692612A (en) * 2017-01-17 2017-05-24 韦朝岚 Medicinal powder formula of seamless woundplast and seamless woundplast producing method

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2093643U (en) * 1991-07-17 1992-01-22 卫玉秀 Herb-containing medical dressing
CN1327828A (en) * 2001-06-12 2001-12-26 马永明 Adhesive bandage able to relieve inflammation, astringe and grow muscle and its preparing process
CN103285421A (en) * 2012-02-29 2013-09-11 朱建华 Transparent waterproof wound paster

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2093643U (en) * 1991-07-17 1992-01-22 卫玉秀 Herb-containing medical dressing
CN1327828A (en) * 2001-06-12 2001-12-26 马永明 Adhesive bandage able to relieve inflammation, astringe and grow muscle and its preparing process
CN103285421A (en) * 2012-02-29 2013-09-11 朱建华 Transparent waterproof wound paster

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104027200A (en) * 2014-03-20 2014-09-10 周义福 Preparation method of ginger powder band-aids
CN104288355A (en) * 2014-08-30 2015-01-21 彭殿英 Traditional Chinese medicine for treating furuncles
CN105797199A (en) * 2016-04-07 2016-07-27 杨兰 Band-aid containing pu'er tea extract
CN106692612A (en) * 2017-01-17 2017-05-24 韦朝岚 Medicinal powder formula of seamless woundplast and seamless woundplast producing method

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