CN103584950A - Method for preparing pearl powder adhesive bandage - Google Patents
Method for preparing pearl powder adhesive bandage Download PDFInfo
- Publication number
- CN103584950A CN103584950A CN201310635082.2A CN201310635082A CN103584950A CN 103584950 A CN103584950 A CN 103584950A CN 201310635082 A CN201310635082 A CN 201310635082A CN 103584950 A CN103584950 A CN 103584950A
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- adhesive bandage
- substrate
- margarita powder
- preparation
- medicine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000000853 adhesive Substances 0.000 title claims abstract description 40
- 230000001070 adhesive effect Effects 0.000 title claims abstract description 36
- 239000000843 powder Substances 0.000 title claims abstract description 36
- 238000000034 method Methods 0.000 title abstract description 13
- 239000003814 drug Substances 0.000 claims abstract description 19
- 239000000758 substrate Substances 0.000 claims abstract description 14
- -1 polyethylene Polymers 0.000 claims abstract description 8
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 8
- 239000004745 nonwoven fabric Substances 0.000 claims abstract description 5
- 239000004698 Polyethylene Substances 0.000 claims abstract description 4
- 229920000573 polyethylene Polymers 0.000 claims abstract description 4
- 238000001035 drying Methods 0.000 claims abstract description 3
- 239000002994 raw material Substances 0.000 claims abstract description 3
- 239000002904 solvent Substances 0.000 claims abstract description 3
- 244000293323 Cosmos caudatus Species 0.000 claims description 24
- 235000005956 Cosmos caudatus Nutrition 0.000 claims description 24
- 241000628997 Flos Species 0.000 claims description 12
- 238000002360 preparation method Methods 0.000 claims description 12
- 229920002498 Beta-glucan Polymers 0.000 claims description 10
- FYGDTMLNYKFZSV-URKRLVJHSA-N (2s,3r,4s,5s,6r)-2-[(2r,4r,5r,6s)-4,5-dihydroxy-2-(hydroxymethyl)-6-[(2r,4r,5r,6s)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1[C@@H](CO)O[C@@H](OC2[C@H](O[C@H](O)[C@H](O)[C@H]2O)CO)[C@H](O)[C@H]1O FYGDTMLNYKFZSV-URKRLVJHSA-N 0.000 claims description 9
- 239000003795 chemical substances by application Substances 0.000 claims description 8
- 230000002195 synergetic effect Effects 0.000 claims description 8
- 235000011837 pasties Nutrition 0.000 claims description 7
- 235000008216 herbs Nutrition 0.000 claims description 6
- 239000012153 distilled water Substances 0.000 claims description 5
- 235000014113 dietary fatty acids Nutrition 0.000 claims description 4
- 229930195729 fatty acid Natural products 0.000 claims description 4
- 239000000194 fatty acid Substances 0.000 claims description 4
- 239000011049 pearl Substances 0.000 claims description 4
- 244000025254 Cannabis sativa Species 0.000 claims description 2
- 241000237536 Mytilus edulis Species 0.000 claims description 2
- 229930006000 Sucrose Natural products 0.000 claims description 2
- 244000269722 Thea sinensis Species 0.000 claims description 2
- 239000002671 adjuvant Substances 0.000 claims description 2
- 235000012054 meals Nutrition 0.000 claims description 2
- 235000020638 mussel Nutrition 0.000 claims description 2
- 239000001397 quillaja saponaria molina bark Substances 0.000 claims description 2
- 229930182490 saponin Natural products 0.000 claims description 2
- 150000007949 saponins Chemical class 0.000 claims description 2
- 239000013535 sea water Substances 0.000 claims description 2
- 238000007493 shaping process Methods 0.000 claims description 2
- 239000005720 sucrose Substances 0.000 claims description 2
- 206010061218 Inflammation Diseases 0.000 abstract description 7
- 230000035876 healing Effects 0.000 abstract description 6
- 230000035699 permeability Effects 0.000 abstract description 5
- 239000000203 mixture Substances 0.000 abstract description 4
- 230000000740 bleeding effect Effects 0.000 abstract description 3
- 238000002474 experimental method Methods 0.000 abstract description 2
- 230000004054 inflammatory process Effects 0.000 abstract description 2
- 230000008961 swelling Effects 0.000 abstract description 2
- 229940079593 drug Drugs 0.000 abstract 3
- 230000003467 diminishing effect Effects 0.000 abstract 2
- 241001565331 Margarodes Species 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 230000000694 effects Effects 0.000 description 12
- 206010040943 Skin Ulcer Diseases 0.000 description 7
- 231100000019 skin ulcer Toxicity 0.000 description 7
- 238000005469 granulation Methods 0.000 description 6
- 230000003179 granulation Effects 0.000 description 6
- 230000001737 promoting effect Effects 0.000 description 6
- 208000027418 Wounds and injury Diseases 0.000 description 4
- 230000003110 anti-inflammatory effect Effects 0.000 description 4
- 230000023597 hemostasis Effects 0.000 description 4
- 241000411851 herbal medicine Species 0.000 description 4
- 238000005457 optimization Methods 0.000 description 4
- 238000005520 cutting process Methods 0.000 description 3
- 238000010298 pulverizing process Methods 0.000 description 3
- 208000024891 symptom Diseases 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 2
- 206010007247 Carbuncle Diseases 0.000 description 1
- 201000006082 Chickenpox Diseases 0.000 description 1
- 201000004624 Dermatitis Diseases 0.000 description 1
- 206010017553 Furuncle Diseases 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 206010046980 Varicella Diseases 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 208000010668 atopic eczema Diseases 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 208000003512 furunculosis Diseases 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/02—Adhesive bandages or dressings
- A61F13/0276—Apparatus or processes for manufacturing adhesive dressings or bandages
- A61F13/0289—Apparatus or processes for manufacturing adhesive dressings or bandages manufacturing of adhesive dressings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/44—Medicaments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/02—Adhesive bandages or dressings
- A61F13/0276—Apparatus or processes for manufacturing adhesive dressings or bandages
- A61F2013/0296—Apparatus or processes for manufacturing adhesive dressings or bandages for making transdermal patches (chemical processes excluded)
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Biomedical Technology (AREA)
- Manufacturing & Machinery (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Materials Engineering (AREA)
- Epidemiology (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to a method for preparing a pearl powder adhesive bandage. The method sequentially includes the following steps that (1) pearl powder, auxiliary herb medicines and natural synergists are taken as raw materials, the pearl powder is ground, the auxiliary herb medicines are smashed, then the ground pearl powder and the smashed auxiliary herb medicines are mixed with the natural synergists, and water is added, so that the mixture is pulpy; (2) a porous polyethylene film or a non-woven fabric serves as a substrate, the substrate is cut to be oval, and the central area of the substrate is coated with adhesives; (3) the pulpy medicine obtained in the step (1) is made to be rectangular, solvents are volatilized through drying, then the pulpy medicine is attached to the substrate with the adhesives, and ultimately, release paper or films are placed on the rectangular medicine. The adhesive bandage is soft and smooth in hand feeling, the permeability of the medicine is high, the breathability is good, bleeding stopping and heating are quick to achieve, and as is proved in clinical experiments, the adhesive bandage has ideal functions on diminishing inflammation, stopping bleeding, diminishing swelling, healing sores, engendering flesh and the like.
Description
Technical field
The present invention relates to a kind of Margarita powder adhesive bandage, relate to especially a kind of adhesive bandage with anti-inflammation hemostasia, convergence granulation promoting function and medical value, and the preparation method of this adhesive bandage.
Background technology
Adhesive bandage is a kind of very extensive and convenient curable product that uses in daily life.The kind of adhesive bandage is a lot of in the market, but the effect that skin ulcer is protected in existing most of adhesive bandage hemostasis is also not obvious, can not meet the requirement of the simple and efficient healing of wound of people.As Chinese patent 02117251.X discloses a kind of flexible fabric bandage with Chinese medicine, although have certain anti-inflammatory analgetic effect, effect is unsatisfactory, and it is slow to take effect; Patent 201210583344.0 discloses a kind of Chinese herbal medicine adhesive bandage, though Chinese herbal medicine has certain hemostasia and dissipation blood stasis effect, but it is slow to take effect, and need use for a long time.
Summary of the invention
The object of this invention is to provide a kind of instant effect, permeability good, there is excellent air permeability and adhesion property, and the Margarita powder adhesive bandage simultaneously with functions such as hemostasia and detumescence, eliminating inflammation and expelling toxin, convergence granulation promotings, the wound of skin, eczema chickenpox, injury from falling down, post surgery treatment, carbuncle furunculosis, congestion and swelling pain etc. are all had to significant curative effect, to overcome the defect of the aspects such as existing slow, the function singleness of taking effect of existing adhesive bandage.
The technical solution adopted for the present invention to solve the technical problems is:
The preparation method of Margarita powder adhesive bandage, is characterized in that in turn including the following steps: the (1) preparation of adhesive bandage medicine, the (2) preparation of adhesive bandage substrate, the (3) shaping of adhesive bandage.
As the further optimization to technique scheme, wherein
(1) step comprises: using Margarita powder, auxiliary medicinal herbs and natural synergic agent is raw material, and Margarita powder is ground, and adjuvant grass meal is broken, then mixes with natural synergic agent, adds water furnishing pasty state;
(2) step comprises: adopting polyethylene film or the non-woven fabrics of porous is substrate, substrate is cut into ellipse, and coats adhesive agent in central area;
(3) step comprises: the pasty medicament that (1) step is prepared is made oblong-shaped, and drying vapors away solvent, sticks in the substrate that scribbles adhesive agent, finally on rectangle medicine, puts release paper or film.
As the further optimization to technique scheme, step (1) in, described Margarita powder is micro-nano sea water pearls powder or micro-nano mussel pearl powder, granularity is 100-500nm; Described auxiliary medicinal herbs are a kind of or any multiple combination in Radix Paeoniae Rubra, Herba Portulacae, Flos Lonicerae, Herba Taraxaci, Herba Violae, Flos Chrysanthemi Indici, Radix Angelicae Pubescentis and Ramulus Mori; Described natural synergic agent is a kind of or any multiple combination in beta glucan, sorbitan fatty acid ester, sucrose fatty acid ester and tea saponin.
As the further optimization to technique scheme, step (1) in, described auxiliary medicinal herbs are the combination of Radix Paeoniae Rubra, Flos Lonicerae, Radix Angelicae Pubescentis, described natural synergic agent is beta glucan, each components by weight is: Margarita powder 70%-90%; Radix Paeoniae Rubra 2%-5%; Flos Lonicerae 2%-3%; Radix Angelicae Pubescentis 2%-3%; Beta glucan 2%-10%; Distilled water 2%-9%.
As the further optimization to technique scheme, step (2) in, described substrate is cut into semi-major axis 2.5cm, the ellipse of semi-minor axis 1cm.
Adhesive bandage of the present invention is soft smooth, and the permeability of medicine is strong, and good air permeability, and arresting bleeding and healing the wound is fast, through clinical trial, proves, the effects such as the anti-inflammation hemostasia of this adhesive bandage, detumescence sore, convergence granulation promoting are quite desirable.
Below in conjunction with embodiment, the present invention is further described.
The specific embodiment
In the present invention, Margarita powder, Radix Angelicae Pubescentis, Radix Paeoniae Rubra, Flos Lonicerae are conventional Chinese herbal medicine, and beta glucan can adopt the disclosed method of document (International Journal of Cancer.Infec.Immuno.1985.20,804-810) to be prepared.
The manufacture method of the Chinese herbal medicine that term processed with wine, parch are a kind of routine, the method also has detailed introduction in the quality of < < Chinese medicine and in rationally applying > > (Jiangsu science tech publishing house) book.
Embodiment mono-:
Get 8.5 grams of Margarita powder, 0.2 gram of Radix Paeoniae Rubra processed with wine, 0.25 gram of Radix Angelicae Pubescentis parch, 0.25 gram of Flos Lonicerae, 0.6 gram of beta glucan, adopt the method for stage reduction, above-mentioned each medicine is crushed to granularity 300 order left and right, powder after pulverizing is added to 0.2 gram of distilled water furnishing pasty state, and mix homogeneously, coats on non-woven fabrics, by required size, carry out cutting again, obtain anti-inflammation hemostasia, convergence granulation promoting, detumescence treatment skin ulcer adhesive bandage.
Margarita powder adhesive bandage is to hemostasis, pain relieving, antiinflammatory, the skin ulcer cardinal symptom observation of curative effect result table of healing
Embodiment bis-:
Get 17 grams of Margarita powder, 0.4 gram of Radix Paeoniae Rubra processed with wine, 0.5 gram of Radix Angelicae Pubescentis parch, 0.5 gram of Flos Lonicerae, 1.1 grams of beta glucans, adopt the method for stage reduction, above-mentioned each medicine is crushed to granularity 300 order left and right, powder after pulverizing is added to 0.4 gram of distilled water furnishing pasty state, and mix homogeneously, coats on the polyethylene film of porous, by required size, carry out cutting again, obtain anti-inflammation hemostasia, convergence granulation promoting, detumescence treatment skin ulcer adhesive bandage.
Margarita powder adhesive bandage is to hemostasis, pain relieving, antiinflammatory, the skin ulcer cardinal symptom observation of curative effect result table of healing
Embodiment tri-:
Get 9 grams of Margarita powder, 0.3 gram of Radix Paeoniae Rubra processed with wine, 0.25 gram of Radix Angelicae Pubescentis parch, 0.25 gram of Flos Lonicerae, 0.6 gram of beta glucan, adopt the method for stage reduction, above-mentioned each medicine is crushed to granularity 300 order left and right, powder after pulverizing is added to 0.3 gram of distilled water furnishing pasty state, and mix homogeneously, coats on non-woven fabrics, by required size, carry out cutting again, obtain anti-inflammation hemostasia, convergence granulation promoting, detumescence treatment skin ulcer adhesive bandage.
Margarita powder adhesive bandage is to hemostasis, pain relieving, antiinflammatory, the skin ulcer cardinal symptom observation of curative effect result table of healing
More than describe preferred embodiment of the present invention in detail.Should be appreciated that those of ordinary skill in the art just can design according to the present invention make many modifications and variations without creative work.Therefore, all technical staff in the art on the basis of existing technology by the available technical scheme of logical analysis, reasoning, or a limited experiment, all should fall within the scope of protection of the present invention under this invention's idea.
Claims (5)
1. the preparation method of Margarita powder adhesive bandage, is characterized in that in turn including the following steps: the (1) preparation of adhesive bandage medicine, the (2) preparation of adhesive bandage substrate, the (3) shaping of adhesive bandage.
2. the preparation method of Margarita powder adhesive bandage according to claim 1, is characterized in that wherein
(1) step comprises: using Margarita powder, auxiliary medicinal herbs and natural synergic agent is raw material, and Margarita powder is ground, and adjuvant grass meal is broken, then mixes with natural synergic agent, adds water furnishing pasty state;
(2) step comprises: adopting polyethylene film or the non-woven fabrics of porous is substrate, substrate is cut into ellipse, and coats adhesive agent in central area;
(3) step comprises: the pasty medicament that (1) step is prepared is made oblong-shaped, and drying vapors away solvent, sticks in the substrate that scribbles adhesive agent, finally on rectangle medicine, puts release paper or film.
3. the preparation method of Margarita powder adhesive bandage according to claim 2, is characterized in that step (1), and described Margarita powder is micro-nano sea water pearls powder or micro-nano mussel pearl powder, and granularity is 100-500nm; Described auxiliary medicinal herbs are a kind of or any multiple combination in Radix Paeoniae Rubra, Herba Portulacae, Flos Lonicerae, Herba Taraxaci, Herba Violae, Flos Chrysanthemi Indici, Radix Angelicae Pubescentis and Ramulus Mori; Described natural synergic agent is a kind of or any multiple combination in beta glucan, sorbitan fatty acid ester, sucrose fatty acid ester and tea saponin.
4. the preparation method of Margarita powder adhesive bandage according to claim 3, in it is characterized in that step (1), described auxiliary medicinal herbs are the combination of Radix Paeoniae Rubra, Flos Lonicerae, Radix Angelicae Pubescentis, and described natural synergic agent is beta glucan, and each components by weight is: Margarita powder 70%-90%; Radix Paeoniae Rubra 2%-5%; Flos Lonicerae 2%-3%; Radix Angelicae Pubescentis 2%-3%; Beta glucan 2%-10%; Distilled water 2%-9%.
5. the preparation method of Margarita powder adhesive bandage according to claim 2, is characterized in that step (2), and described substrate is cut into semi-major axis 2.5cm, the ellipse of semi-minor axis 1cm.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN201310635082.2A CN103584950B (en) | 2013-12-02 | 2013-12-02 | Method for preparing pearl powder adhesive bandage |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201310635082.2A CN103584950B (en) | 2013-12-02 | 2013-12-02 | Method for preparing pearl powder adhesive bandage |
Publications (2)
Publication Number | Publication Date |
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CN103584950A true CN103584950A (en) | 2014-02-19 |
CN103584950B CN103584950B (en) | 2015-07-08 |
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CN201310635082.2A Active CN103584950B (en) | 2013-12-02 | 2013-12-02 | Method for preparing pearl powder adhesive bandage |
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Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104027200A (en) * | 2014-03-20 | 2014-09-10 | 周义福 | Preparation method of ginger powder band-aids |
CN104288355A (en) * | 2014-08-30 | 2015-01-21 | 彭殿英 | Traditional Chinese medicine for treating furuncles |
CN105797199A (en) * | 2016-04-07 | 2016-07-27 | 杨兰 | Band-aid containing pu'er tea extract |
CN106692612A (en) * | 2017-01-17 | 2017-05-24 | 韦朝岚 | Medicinal powder formula of seamless woundplast and seamless woundplast producing method |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN2093643U (en) * | 1991-07-17 | 1992-01-22 | 卫玉秀 | Herb-containing medical dressing |
CN1327828A (en) * | 2001-06-12 | 2001-12-26 | 马永明 | Adhesive bandage able to relieve inflammation, astringe and grow muscle and its preparing process |
CN103285421A (en) * | 2012-02-29 | 2013-09-11 | 朱建华 | Transparent waterproof wound paster |
-
2013
- 2013-12-02 CN CN201310635082.2A patent/CN103584950B/en active Active
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN2093643U (en) * | 1991-07-17 | 1992-01-22 | 卫玉秀 | Herb-containing medical dressing |
CN1327828A (en) * | 2001-06-12 | 2001-12-26 | 马永明 | Adhesive bandage able to relieve inflammation, astringe and grow muscle and its preparing process |
CN103285421A (en) * | 2012-02-29 | 2013-09-11 | 朱建华 | Transparent waterproof wound paster |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104027200A (en) * | 2014-03-20 | 2014-09-10 | 周义福 | Preparation method of ginger powder band-aids |
CN104288355A (en) * | 2014-08-30 | 2015-01-21 | 彭殿英 | Traditional Chinese medicine for treating furuncles |
CN105797199A (en) * | 2016-04-07 | 2016-07-27 | 杨兰 | Band-aid containing pu'er tea extract |
CN106692612A (en) * | 2017-01-17 | 2017-05-24 | 韦朝岚 | Medicinal powder formula of seamless woundplast and seamless woundplast producing method |
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CN103584950B (en) | 2015-07-08 |
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