CN1299714C - Method for preparing traditional Chinese compound ointment - Google Patents
Method for preparing traditional Chinese compound ointment Download PDFInfo
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- CN1299714C CN1299714C CNB031097367A CN03109736A CN1299714C CN 1299714 C CN1299714 C CN 1299714C CN B031097367 A CNB031097367 A CN B031097367A CN 03109736 A CN03109736 A CN 03109736A CN 1299714 C CN1299714 C CN 1299714C
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- ointment
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- dermopathic
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Abstract
The present invention relates to Chinese medicinal compound ointment which is mainly composed of coptis root, Chinese gall and other auxiliary materials. The present invention also has a preparation method that the coptis root is pulverized for standby, the Chinese gall is warmly soaked and concentrated into powder by way of spray drying, and ointment is prepared after the two drugs are added into simple ointment substrates. Substances that are prepared with the method can be used for treating dermatosis.
Description
Technical field the present invention relates to a kind of Chinese medicine compound ointment, mainly by Rhizoma Coptidis. and Galla Chinensis and other adjuvant are formed.
Background technology baby's diaper dermatitis is common pediatric disease, and decubital ulcer is the disease that the long-term bed patient easily sees, is perplexing many patients.The Chinese medicine that is used for above-mentioned two kinds of diseases clinically is also few, and in the Chinese medicine, Galla Chinensis has the function that removing dampness is held back skin ulcer, and Rhizoma Coptidis has heat clearing and damp drying, the effect of eliminating fire and detoxication.Ointment can directly act on human body by Transdermal absorption, and preparation method mostly is that medical material directly is used as medicine or make ointment after water extract-alcohol precipitation is made extractum again.Therefore, prepare one and can be used for baby's diaper dermatitis and decubital ulcer, and adopt the medicine of new method of Chinese medicinal preparation can be more selection is provided clinically.
Summary of the invention the objective of the invention is to set up a kind of new Chinese medicine compound ointment formulation method, can be used for treating dermatosis with the medicine of its preparation.
Technical scheme of the present invention is: a kind of ointment, to form by 1 portion of Rhizoma Coptidis and 2～4 parts of Galla Chinensiss, and other is a cream substrate adjuvant.Wherein adjuvant can be: ointment bases such as magnesium stearate, paraffin wax, white oil, lanoline.Its preparation method is:
(1) get Rhizoma Coptidis. sieve after crushed, standby;
(2) get Galla Chinensis, the water warm macerating is collected leachate after crushed, filters, and removes impurity, and filtrate gets concentrated solution through thin film concentration, with gained liquid spray drying, makes powder, and is standby;
(3) preparation simple Ointment substrate.
(4) medical material in the step (1) (2) is handled in the simple Ointment substrate of spares adding (3), and added an amount of essence, stir, make ointment.
Wherein the breaking method described in the step (1) can be micronizing, crosses 100～200 mesh sieves.
Wherein the water temperature described in the step (2) is soaked temperature and can be 40～60 ℃, and the warm macerating time can be 24～72 hours.
The spray drying described in the step (2) wherein, its inlet temperature can be 160～220 ℃, and leaving air temp can be 80～120 ℃, and the feed pump frequency is 30～80HZ.
Wherein the method for preparing simple Ointment substrate described in the step (3) can be: get 5～8 parts of hard ester acid, 1～3 part of paraffin wax, 2～4 parts of white oils, 1～2 part of anhydrous lanolin, heat fused filters, 70～75 ℃ be incubated substance A; Other gets 1～2 part of glycerol, 1～2 part of triethanolamine, and antiseptic and distilled water are an amount of, heating for dissolving, 70～75 ℃ of insulations get substance B; Under stirring .B fully mixes with substance A, makes substrate.
Compared with prior art, the present invention has adopted the compound preparation of Galla Chinensis and Rhizoma Coptidis, and adopts new technology, and the material of its preparation can be used for the treatment of dermatosis.
The present invention is further illustrated below in conjunction with a plurality of specific embodiment for the specific embodiment:
Respectively get Galla Chinensis 100g, with the contrast of different warm macerating time and warm macerating temperature, with leaching rate as index:
| The warm macerating time (hour) | The warm macerating temperature (℃) | Leaching rate |
| 24 24 48 48 | 45 55 45 55 | 36％ 43％ 42％ 45％ |
Get concentrated solution, experimentize, compare with the character and the water content of powder by different out temperatures.
| Inlet temperature | Leaving air temp | Character and water content |
| 180 190 200 215 | 81 87 92 95 | Character is general, and the phenomenon of sticking is arranged, and water content is higher relatively.Character is good, and less sticking arranged, and water content is low relatively.Character is better, has sallow on a small quantity, dry.Character is better, and a small amount of carbonization is arranged. |
Adopted multiple adjuvant to carry out the preparation of single substrate ointment, employing method following (unit is gram):
| Scheme | Substance A | Substance B | ||||
| Magnesium stearate | Paraffin wax | White oil | Anhydrous lanolin | Glycerol | Triethanolamine | |
| 1 2 3 4 | 150 150 200 200 | 60 30 0 30 | 90 80 100 80 | 20 30 20 0 | 50 60 60 50 | 30 30 40 40 |
More than the conventional system of four kinds of schemes utilization ointment methods all be prepared into single substrate ointment.
Claims (8)
1. one kind is used for the treatment of dermopathic ointment, it is characterized in that: it is prepared into through extracting the extract powder and the cream substrate adjuvant that obtain after the processing by the Golden Thread of 1 weight portion and the Galla Chinensis of 2～4 weight portions.
2. be used for the treatment of dermopathic ointment according to claim 1 is described, it is characterized in that: adjuvant is: magnesium stearate, paraffin wax, white oil or lanoline.
3. be used for the treatment of the preparation method of dermopathic ointment as claimed in claim 1 or 2, it is characterized in that:
(1) get Rhizoma Coptidis, sieve after crushed, standby;
(2) get Galla Chinensis, the water warm macerating is collected leachate after crushed, filters, and removes impurity, and filtrate gets concentrated solution through thin film concentration, with gained liquid spray drying, makes powder, and is standby;
(3) preparation simple Ointment substrate;
(4) medical material in step (1), (2) is handled in the simple Ointment substrate of spares adding (3), and
Add an amount of essence, stir, make ointment.
4. according to the described preparation method that is used for the treatment of dermopathic ointment of claim 3, it is characterized in that: the breaking method to Rhizoma Coptidis is a micronizing.
5. according to the described preparation method that is used for the treatment of dermopathic ointment of claim 3, it is characterized in that: it is 40～60 ℃ that the water temperature described in the step (2) is soaked temperature, and the warm macerating time is 24～48 hours.
6. according to the described preparation method that is used for the treatment of dermopathic ointment of claim 3, it is characterized in that: the spray drying described in the step (2), its inlet temperature are 160～220 ℃, and leaving air temp is 80～120 ℃, and the feed pump frequency is 30～80Hz.
7. according to the described preparation method that is used for the treatment of dermopathic ointment of claim 3, it is characterized in that: the method for preparing simple Ointment substrate described in the step (3) is: get hard ester acid 5～8 weight portions, paraffin wax 1～3 weight portion, white oil 2～4 weight portions, anhydrous lanolin 1～2 weight portion, heat fused filters, 70～75 ℃ of insulations get substance A; Other gets glycerol 1～2 weight portion, triethanolamine 1～2 weight portion, and antiseptic and distilled water are an amount of, heating for dissolving, 70～75 ℃ of insulations get substance B; Under stirring, B fully mixes with substance A, makes substrate.
8. be used for the treatment of the application of dermopathic ointment as claimed in claim 1 or 2, it is characterized in that: the application of described ointment in preparation treatment dermatosis medicine.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB031097367A CN1299714C (en) | 2003-04-14 | 2003-04-14 | Method for preparing traditional Chinese compound ointment |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB031097367A CN1299714C (en) | 2003-04-14 | 2003-04-14 | Method for preparing traditional Chinese compound ointment |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1537548A CN1537548A (en) | 2004-10-20 |
| CN1299714C true CN1299714C (en) | 2007-02-14 |
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ID=34319496
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB031097367A Expired - Fee Related CN1299714C (en) | 2003-04-14 | 2003-04-14 | Method for preparing traditional Chinese compound ointment |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1299714C (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103372068A (en) * | 2012-04-16 | 2013-10-30 | 贾庆东 | Formula and preparation method of novel gold paste |
| CN104257786B (en) * | 2014-10-20 | 2018-01-30 | 重庆市中药研究院 | A kind of coptis external preparation, preparation method and applications |
| CN106511410A (en) * | 2017-01-03 | 2017-03-22 | 遵义医学院 | Herba Saxifragae ointment for treating skin diseases and preparation method of Herba Saxifragae ointment for treating skin diseases |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1174064A (en) * | 1997-07-18 | 1998-02-25 | 迟经惠 | Eczema ointment |
| CN1376487A (en) * | 2001-11-15 | 2002-10-30 | 高伯峰 | Detoxicating and skin-growing ointment for treating burn |
-
2003
- 2003-04-14 CN CNB031097367A patent/CN1299714C/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1174064A (en) * | 1997-07-18 | 1998-02-25 | 迟经惠 | Eczema ointment |
| CN1376487A (en) * | 2001-11-15 | 2002-10-30 | 高伯峰 | Detoxicating and skin-growing ointment for treating burn |
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| Publication number | Publication date |
|---|---|
| CN1537548A (en) | 2004-10-20 |
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Granted publication date: 20070214 Termination date: 20140414 |