CN1298330C - 自我施用的油性溶液的避孕注射 - Google Patents

自我施用的油性溶液的避孕注射 Download PDF

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Publication number
CN1298330C
CN1298330C CNB038123622A CN03812362A CN1298330C CN 1298330 C CN1298330 C CN 1298330C CN B038123622 A CNB038123622 A CN B038123622A CN 03812362 A CN03812362 A CN 03812362A CN 1298330 C CN1298330 C CN 1298330C
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CN
China
Prior art keywords
etonogestrel
undecanoate
injection
ment
needle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CNB038123622A
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English (en)
Chinese (zh)
Other versions
CN1655847A (zh
Inventor
H·德尼耶斯
H·A·A·范德尔伍尔特
D·雷森
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Organon NV
Akzo Nobel NV
Original Assignee
Organon NV
Akzo Nobel NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Organon NV, Akzo Nobel NV filed Critical Organon NV
Publication of CN1655847A publication Critical patent/CN1655847A/zh
Application granted granted Critical
Publication of CN1298330C publication Critical patent/CN1298330C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021—Intradermal administration, e.g. through microneedle arrays or needleless injectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/569—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/16—Masculine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Reproductive Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
CNB038123622A 2002-05-30 2003-05-23 自我施用的油性溶液的避孕注射 Expired - Fee Related CN1298330C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP02077126.7 2002-05-30
EP02077126 2002-05-30

Publications (2)

Publication Number Publication Date
CN1655847A CN1655847A (zh) 2005-08-17
CN1298330C true CN1298330C (zh) 2007-02-07

Family

ID=29595016

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB038123622A Expired - Fee Related CN1298330C (zh) 2002-05-30 2003-05-23 自我施用的油性溶液的避孕注射

Country Status (23)

Country Link
US (1) US20060094698A1 (enExample)
EP (1) EP1513587A1 (enExample)
JP (1) JP2005533036A (enExample)
KR (1) KR20050010014A (enExample)
CN (1) CN1298330C (enExample)
AR (1) AR040131A1 (enExample)
AU (1) AU2003238084A1 (enExample)
BR (1) BR0311423A (enExample)
CA (1) CA2487639A1 (enExample)
HR (1) HRP20041126A2 (enExample)
IL (1) IL165204A0 (enExample)
IS (1) IS7539A (enExample)
MX (1) MXPA04011928A (enExample)
NO (1) NO20044976L (enExample)
NZ (1) NZ536735A (enExample)
PE (1) PE20040676A1 (enExample)
PL (1) PL373074A1 (enExample)
RS (1) RS100904A (enExample)
RU (1) RU2328289C2 (enExample)
TW (1) TW200404552A (enExample)
UA (1) UA80822C2 (enExample)
WO (1) WO2003101539A1 (enExample)
ZA (1) ZA200409646B (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200727920A (en) * 2005-06-21 2007-08-01 Organon Nv New regimens for oral monophasic contraceptives
KR20150011346A (ko) 2012-04-06 2015-01-30 안타레스 팔마, 인코퍼레이티드 테스토스테론 조성물의 바늘-보조식 젯 주입 투여 장치 및 방법
WO2014093818A2 (en) * 2012-12-14 2014-06-19 Bioject, Inc. Use of a novel subcutaneous needle-free technique to deliver testosterone in hypogonadal men
DK2953667T3 (da) * 2013-02-11 2020-01-27 Antares Pharma Inc Nålestøttet jetinjektionsindretning med reduceret udløserkraft
WO2015023557A1 (en) 2013-08-12 2015-02-19 Nanomedical Systems, Inc. Device and method for sustained release of low water solubility therapeutic agent in solubilizer
CN114026106B (zh) * 2019-03-06 2025-01-21 普洛拉治疗公司 阿比特龙前药
CN111057120B (zh) * 2019-12-27 2021-04-27 苏州翔实医药发展有限公司 一种依托孕烯衍生物a及其制备方法和用途

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001060376A1 (en) * 2000-02-15 2001-08-23 Schering Aktiengesellschaft Male contraceptive formulation comprising norethisterone
WO2002015938A2 (en) * 2000-08-23 2002-02-28 Akzo Nobel N.V. Testosterone ester formulation for human use

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2970153A (en) * 1959-07-27 1961-01-31 Leo Ab Alkoxyphenyl-propionyl esters of 17alpha-hydroxyprogesterone
DE3836862A1 (de) * 1988-10-27 1990-05-03 Schering Ag Mittel zur transdermalen applikation von steroidhormonen
CN1102095A (zh) * 1993-10-30 1995-05-03 浙江医科大学 长效雄激素类制剂——十一酸睾丸注射液
CN1135716A (zh) * 1993-12-27 1996-11-13 阿克佐诺贝尔公司 经皮吸收的药用制剂
US5599302A (en) * 1995-01-09 1997-02-04 Medi-Ject Corporation Medical injection system and method, gas spring thereof and launching device using gas spring
WO1997003709A1 (de) * 1995-07-17 1997-02-06 Schering Aktiengesellschaft Mittel zur transdermalen applikation enthaltend ester des 3-ketodegestrel
TR200003743T2 (tr) * 1998-06-19 2001-07-23 Akzo Nobel N.V. Testosteron türevi.
WO1999067270A1 (en) * 1998-06-19 1999-12-29 Akzo Nobel N.V. Cycloalkyl-carboxylic acid esters of 7.alpha.methyl-estr-4-en-3-one 17.beta.-ol (19-nor 7.alpha.-methyltestosterone)
GB0000313D0 (en) * 2000-01-10 2000-03-01 Astrazeneca Uk Ltd Formulation

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001060376A1 (en) * 2000-02-15 2001-08-23 Schering Aktiengesellschaft Male contraceptive formulation comprising norethisterone
WO2002015938A2 (en) * 2000-08-23 2002-02-28 Akzo Nobel N.V. Testosterone ester formulation for human use

Also Published As

Publication number Publication date
RU2328289C2 (ru) 2008-07-10
CN1655847A (zh) 2005-08-17
PE20040676A1 (es) 2004-09-25
IS7539A (is) 2004-11-18
BR0311423A (pt) 2005-03-15
MXPA04011928A (es) 2005-03-31
IL165204A0 (en) 2005-12-18
US20060094698A1 (en) 2006-05-04
TW200404552A (en) 2004-04-01
KR20050010014A (ko) 2005-01-26
EP1513587A1 (en) 2005-03-16
UA80822C2 (en) 2007-11-12
CA2487639A1 (en) 2003-12-11
RU2004138811A (ru) 2005-06-10
AU2003238084A1 (en) 2003-12-19
AR040131A1 (es) 2005-03-16
HRP20041126A2 (en) 2005-04-30
NO20044976L (no) 2004-12-23
JP2005533036A (ja) 2005-11-04
WO2003101539A1 (en) 2003-12-11
RS100904A (sr) 2006-10-27
NZ536735A (en) 2007-01-26
ZA200409646B (en) 2006-06-28
PL373074A1 (en) 2005-08-08

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