CN1291485A - Medicine for quickly treating acne abscess and its preparing process - Google Patents
Medicine for quickly treating acne abscess and its preparing process Download PDFInfo
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- CN1291485A CN1291485A CN 00122855 CN00122855A CN1291485A CN 1291485 A CN1291485 A CN 1291485A CN 00122855 CN00122855 CN 00122855 CN 00122855 A CN00122855 A CN 00122855A CN 1291485 A CN1291485 A CN 1291485A
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Abstract
A medicine for quikly treating acne abscess is prepared from tuckahoe, scutellaria root and poeonol etc through scientifically extracting active components and carefully dispensing. Its advantages include quickly taking its curative effect, short course of treatment (2-7 days) and no residual scar.
Description
The present invention relates to a kind of medicine of quickly treating acne abscess, is the Chinese patent medicine of feedstock production with the Chinese herbal medicine specifically, the invention still further relates to this medicine production technology.
In adolescence, because hormonal abnormal secretion impels a large amount of sebum secreted of sebaceous gland.Propiobacterium is resolved into multiple free property fatty acid with sebum in hair follicle, make pore propagation keratinization and obturation, and it is comedo that the sebum stasis of blood is amassed in the interior acne one that just formed, at this moment, fatty acid penetrates peplos and arrives corium and cause local inflammation, promptly forms cyst, pustule.At this moment, the fibroblast hyperplasia keratinization in affected part has just stayed cicatrix, and the health of skin and attractive in appearance in serious harm.
At present, the primary disease Drug therapy is run into following thorny problem both at home and abroad:
1. to include the gel-like externally-applied liniment of 5% benzoyl peroxide, it only is applicable to the initial stage that acne has just formed, and allergic skin and abscess person are difficult for using.
2. skin has only 10-30% to the absorption rate of external liniment, so Chinese medicine class liniment curative effect is also slow, generally will use continuously 1 to 2 months.
3. contain Radix Et Rhizoma Rhei, the Chinese medicine for oral administration of diarrhea inducing agent such as Aloe: not only injure one's stomach, but also because of content of tannin higher, so behind the diarrhea inducing, often can produce the secondary constipation.If oral (3～9 months) can produce the thyroid tumor change for a long time, hepatocellular degeneration etc. are so should not obey for a long time.
The purpose of this invention is to provide a kind of can quickly treating acne abscess and the medicine of spot.
Another object of the present invention provides the production technology of this disease healing potion.
Solution of the present invention is based on motherland's medical science to pathogenetic understanding of acne and Therapeutic Principle; With reference to modern pharmacological research achievement, from motherland's medicine treasure-house, filter out and have heat-clearing and toxic substances removing, removing heat from blood, the diuretic detumescent, the blood circulation and channel invigorating medicine is apt to homologous natural plant, by the theory of Chinese medical science prescription, skim the cream off milk, make its performance have endocrine in the body of making, nucleic acid, protein lipoid anabolism acts on normally, at this moment, nucleic acid in the Propiobacterium thalline, protein anabolism are suppressed and death.
Medicine of the present invention is made by following component: (consumption is a weight in grams)
Flos Lonicerae 5-40 gram Herba Artemisiae Scopariae 5-40 gram Radix Puerariae 5-30 gram
Poria 5-25 gram Radix Rehmanniae 5-25 gram Rhizoma Alismatis 5-30 gram
Radix Salviae Miltiorrhizae 5-30 gram Cortex Moutan 3-15 gram Radix Scutellariae 3-15 gram
The formula optimization weight proportion scope of preparation medicine of the present invention is:
Flos Lonicerae 15-30 gram Herba Artemisiae Scopariae 20-30 gram Radix Puerariae 10-15 gram
Poria 10-15 gram Radix Rehmanniae 10-15 gram Rhizoma Alismatis 10-20 gram
Radix Salviae Miltiorrhizae 10-15 gram Cortex Moutan 3-10 gram Radix Scutellariae 3-10 gram
The optimum weight proportioning of medicine of the present invention is:
Flos Lonicerae 20 gram Herba Artemisiae Scopariaes 25 gram Radix Puerariaes 15 grams
The Poria 10 gram Radix Rehmanniae 15 gram Rhizoma Alismatis 15 grams
Radix Salviae Miltiorrhizae 15 gram Cortex Moutans 5 gram Radix Scutellariaes 5 grams
Usage and dosage: take at twice 1 dose of every day.
Above-mentioned each component is made medicine production technological process of the present invention is:
(1) protogenic medicinal powder is broken into granule greater than 3um.
(2) when 95 degree water temperatures, adopted dynamic intermittent formula water extraction 2 hours.
(3) adopt equipment for separating liquid from solid, medicinal liquid and medicinal residues are separated.
(4) vacuum concentration proportion to 1.4.
(5) spray drying (containing the dry type one-step palletizing)
(6) packing.
According to above-mentioned production technology, can realize controlling automatization easily, its product meets the requirement of medicine food health legislation, reaches the GMP standard.
An important feature of the present invention is to contain a large amount of chlorogenic acids and analyte caffeic acid thereof in the medicament, anaerobe (Propiobacterium) is had extremely strong inhibitory or killing effect, and can combine with cholesterol, reduces the absorption of intestinal to cholesterol.Also contain abundant Flavonoid substances in this medicament, can blood fat reducing, it is sticking to fall blood, microcirculation improvement, wherein, daidzin also can suppress the HMG-COA reductase activity, and body inner cholesterol synthesis capability is reduced.
Zoopery: cause rabbit periphery microcirculation disturbance with high molecular dextran, after this Drug therapy, observe by microcirculation microscope, can see the stagnant hemocyte of the stasis of blood and begin depolymerization, velocity of blood flow is accelerated, and the fluidised form trend is normal, the open increase of capillary network.
Microcirculation mean flow rate synopsis before and after the administration
| Group | Rabbit number (only) | Before the administration (s/mm) | After the administration (s/mm) | The P value |
| Matched group | 10 | 17．40±7．21 | 15．59±5．70 | ＞0．05 |
| Experimental group | 20 | 13．32±1．14 | 6．49±1．19 | ＜0．01 |
Toxicological experiment: drug extract of the present invention every day was fed rat 40 days with 4g/kg (be according to the weight clinical usual amounts 30 times), removed amount of drinking water, outside the urine amount obviously increases, its body weight appetite activity is normal, do not see toxic reaction, irritate stomach dosage every day and use 10g/kg, do not see death in 72 hours.
As follows through 40 case clinical observation results:
| Group | Case load | Symptom | 3-12 hour | 24 hours | 48 hours | 72 hours | 4 to 7 days |
| The treatment group | 30 | Pustular type | Amount of drinking water urine amount increases | Pustule is dry gradually to disappear | Formed a scab the sebum secretion that flattens of pustule obviously reduces | The bleb crust comes off | Spot disappears |
| Experimental group | 10 | Papular type face flushing | Amount of drinking water urine amount increases | Face becomes normally | Pimple disappears gradually | Pimple, spot disappears | |
Experimental group: by taking sugar continuously.V
B.V
PpAfter three days and the symptom that produces.
The experimental group curative effect is slow as seen from the above table, V in this and the body
B.V
Pp. hormone excessive concentration and influenced drug effect.
Claims (6)
1. the medicine of a quickly treating acne abscess is characterized in that the medicine of being made by the following weight proportion raw material:
Flos Lonicerae 5-40 gram Herba Artemisiae Scopariae 5-40 gram Radix Puerariae 5-30 gram
Poria 5-25 gram Radix Rehmanniae 5-25 gram Rhizoma Alismatis 5-30 gram
Radix Salviae Miltiorrhizae 5-30 gram Cortex Moutan 3-15 gram Radix Scutellariae 3-15 gram
2. medicine according to claim 1, wherein the weight proportion of each raw material is:
Flos Lonicerae 15-30 gram Herba Artemisiae Scopariae 20-30 gram Radix Puerariae 10-15 gram
Poria 10-15 gram Radix Rehmanniae 10-15 gram Rhizoma Alismatis 10-20 gram
Radix Salviae Miltiorrhizae 10-15 gram Cortex Moutan 3-10 gram Radix Scutellariae 3-10 gram
3. medicine according to claim 1, wherein the weight proportion of each raw material is:
Flos Lonicerae 20 gram Herba Artemisiae Scopariaes 25 gram Radix Puerariaes 15 grams
The Poria 10 gram Radix Rehmanniae 15 gram Rhizoma Alismatis 15 grams
Radix Salviae Miltiorrhizae 15 gram Cortex Moutans 5 gram Radix Scutellariaes 5 grams
4. according to the described medicine of claim 1,2 or 3, it is characterized in that said medicament is a said dosage form on any pharmaceutics.
5. medicine according to claim 4 is characterized in that said medicament is an electuary, tablet or capsule.
6. medicine production technological process according to claim 5 is:
(1) protogenic medicinal powder is broken into granule greater than 3um.
(2) when 95 degree water temperatures, adopted dynamic intermittent formula water extraction 2 hours.
(3) adopt equipment for separating liquid from solid, medicinal liquid and medicinal residues are separated.
(4) vacuum concentration proportion to 1.4.
(5) spray drying (containing the dry type one-step palletizing)
(6) packing.
According to above-mentioned production technology, can realize controlling automatization easily, its product meets the requirement of medicine food health legislation, reaches the GMP standard.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB001228552A CN1141954C (en) | 2000-08-30 | 2000-08-30 | Medicine for quickly treating acne abscess and its preparing process |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB001228552A CN1141954C (en) | 2000-08-30 | 2000-08-30 | Medicine for quickly treating acne abscess and its preparing process |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1291485A true CN1291485A (en) | 2001-04-18 |
| CN1141954C CN1141954C (en) | 2004-03-17 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB001228552A Expired - Fee Related CN1141954C (en) | 2000-08-30 | 2000-08-30 | Medicine for quickly treating acne abscess and its preparing process |
Country Status (1)
| Country | Link |
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| CN (1) | CN1141954C (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102885751A (en) * | 2012-10-30 | 2013-01-23 | 董成玉 | Making-up paste with wrinkle repairing function |
| CN104721412A (en) * | 2013-12-24 | 2015-06-24 | 康普药业股份有限公司 | Traditional Chinese medicine preparation for treating acnes and preparation method of traditional Chinese medicine preparation |
-
2000
- 2000-08-30 CN CNB001228552A patent/CN1141954C/en not_active Expired - Fee Related
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102885751A (en) * | 2012-10-30 | 2013-01-23 | 董成玉 | Making-up paste with wrinkle repairing function |
| CN102885751B (en) * | 2012-10-30 | 2014-07-02 | 王玉芝 | Making-up paste with wrinkle repairing function |
| CN104721412A (en) * | 2013-12-24 | 2015-06-24 | 康普药业股份有限公司 | Traditional Chinese medicine preparation for treating acnes and preparation method of traditional Chinese medicine preparation |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1141954C (en) | 2004-03-17 |
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| Date | Code | Title | Description |
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| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20040317 Termination date: 20100830 |