CN1291103A - Herbal composition for the prophylaxis and treatment of AIDS - Google Patents

Herbal composition for the prophylaxis and treatment of AIDS Download PDF

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Publication number
CN1291103A
CN1291103A CN98813948A CN98813948A CN1291103A CN 1291103 A CN1291103 A CN 1291103A CN 98813948 A CN98813948 A CN 98813948A CN 98813948 A CN98813948 A CN 98813948A CN 1291103 A CN1291103 A CN 1291103A
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radix stephaniae
stephaniae japonicae
aids
shi
compositions
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CN98813948A
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Chinese (zh)
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颂乔克·空皮塔
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Victory Thailand Herb Co Ltd
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Victory Thailand Herb Co Ltd
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Publication of CN1291103A publication Critical patent/CN1291103A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/59Menispermaceae (Moonseed family), e.g. hyperbaena or coralbead
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9066Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9068Zingiber, e.g. garden ginger
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

A therpeutic composition for the prophylaxis and treatment of AIDS comprising a mixture of nontoxic herbs of well recognised medicinal properties. The herbal composition consists of Stephania venosa Spreng (40-60 mg), Stephania suberosa Forman (40-60 mg), Stephania glabra Roxb. Miers. (40-60 mg), Hedychium coronarium Roem (40-60 mg), Zingiber Officinalis Roscoe (30-50 mg) and Curcurma Amada (30-50 mg). The process of making the composition requires the herbs to be washed, cut into small pieces, dried and separated from all extraneous material. Each herb is then weighted according to predetermined proportions and pulverised together into a powder of about 40-100 mesh, and dried again. The herbal composition can then be filled into hard gelatin capsules. It has been found that the herbal composition improves the physical condition of AIDS patients and can alleviate or cease the symptoms of most opportunistic infections.

Description

Prevention and the herbal-composition for the treatment of AIDS
The present invention relates to medical science and pharmaceutical field.Specifically, the present invention relates to the herbal-composition of prevention and treatment human immune deficiency virus (HIV) disease and acquired immunodeficiency syndrome (AIDS AIDS) and AIDS related pathologies syndrome.
Technical field
Acquired immunodeficiency syndrome (AIDS AIDS) is a kind of pandemic immunosuppressive disease, causes life-threatening opportunistic infection and malignant tumor.This disease is killed the immune accessory cell that plays a crucial role in cell mediated immunity.The carrying out property forfeiture of accessory cell causes health to become can not resisting many antibacterials, virus and parasitic infringement stage in the blood, and the AIDS AIDS VICTIMS dies from opportunistic infection as a result.Isolated that a kind of to be called the retrovirus of human immune deficiency virus (HIV-1) and to pick out it be this sick etiology.
Estimate that the whole world in 1997 has 2,000 3 hundred ten thousand HIV infected patients approximately.These patients' 90% live in developing country, and the new infected patient number in Asia is maximum.
Report some and suppressed the medicine of human immune deficiency virus propagation.These medicines comprise that nucleotide intends reverse transcriptase inhibitors (NRTIs), for example zidovudine, remove second thymidine (lamivudine), d4T (trade name) and protease inhibitor, for example indinavir, ritonavir, nelfinavir (trade name).Can drug combination, for example the prescription of three kinds of medicines generally comprises two kinds of nucleotide and intend reverse transcriptase inhibitors and a kind of protease inhibitor, but their complexity and price is expensive.And these chemical compounds seem that toxicity is excessive and are unsuitable for taking for a long time perhaps have only limited minimizing or eliminate the ability that HIV infects from the human body host.
According to currently known, the inverase price is high and potential toxicity is arranged, and also is difficult for obtaining to use for most of HIV infected patients of developing country.So all patients need, and price is low, toxicity is little and effective inverase.
In Thailand and Southeast Asia, medical herbs goods/treatment and herbal medicine have been used centuries treatment various diseases.To the naturopathy interest of disease is feasible chemical constitution, toxicity and the effect aspect of medical herbs are studied in recent years.
The purpose of this invention is to provide a kind of herbal-composition that is used to prevent and treat AIDS, and/or a kind of method of using described herbal-composition prevention and treatment AIDS.
Here, term HIV and AIDS refer to be fallen by the virus and the various strains thereof that formally are called HTLV (human close T lymph virus), LAV (Lymphadenopathy-associated virus) and ARV (HIV (human immunodeficiency virus)), are commonly referred to as the virus series of HIV (human immune deficiency virus).
Of the present invention open
The method of a kind of prevention and treatment AIDS and the relevant syndrome of AIDS is proposed in the form of the present invention, comprise the step to animal or people's administering therapeutic effective dose of medicine thing preparation, described preparation comprises the extract of following a kind of or several plants: vein shape Si Pulinshi Radix Stephaniae Japonicae (Stephania venosa Spreng), cork shape good fortune Man Radix Stephaniae Japonicae (Stephaniasuberosa Forman), right this Fu Shi Radix Stephaniae Japonicae (Stephania glabra RoxbMiers) of sieve that does not have hair, coronule around Mo Shi certificate Hedychium coronarium Koenig (Hedychium coronarium Roem), medicinal Roskell ginger (Zingiber officinalis Roscoe) and Armadal curcuma (CurcurmaAmada).
In another form of the present invention, propose a kind ofly to be used to prevent and the compositions for the treatment of AIDS and the relevant syndrome of AIDS, comprise the extract of following a kind of or several plants: vein shape Si Pulinshi Radix Stephaniae Japonicae, cork shape good fortune Man Radix Stephaniae Japonicae, right this Fu Shi Radix Stephaniae Japonicae of sieve that does not have hair, coronule around Mo Shi certificate Hedychium coronarium Koenig, medicinal Roskell ginger and Armadal curcuma.
In another form more of the present invention, propose the method that the HIV with a kind of T lymphocytes in human body of preparation vitro inhibition infected by HIV and mononuclear phagocyte pedigree cell infects, described preparation contains the extract of one or more following at least plants basically: vein shape Si Pulinshi Radix Stephaniae Japonicae, cork shape good fortune Man Radix Stephaniae Japonicae, this Fu Shi Radix Stephaniae Japonicae of sieve right side that does not have hair, coronule around Mo Shi certificate Hedychium coronarium Koenig, medicinal Roskell ginger and Armadal curcuma.
The compositions of a prevention and treatment AIDS and the relevant syndrome of AIDS is proposed in another form of the present invention, comprise the acceptable herbal ingredients of treatment: respectively account for the 18.0-19.0% of gross weight vein shape Si Pulinshi Radix Stephaniae Japonicae, coronule around Mo Shi certificate Hedychium coronarium Koenig, the cork shape good fortune Man Radix Stephaniae Japonicae of 16.0-17.0%, right this Fu Shi Radix Stephaniae Japonicae of sieve that does not have hair and medicinal Roskell ginger, the Armadal curcuma of 14.5-15.5%.
Propose the herbal-composition of a kind of prevention and treatment AIDS and the relevant syndrome of AIDS in another form of the present invention, comprise the following dried plant material of selecting, the ratio of various raw materials is:
Medical herbs name class minimum weight (milligram)
Vein shape Si Pulinshi Radix Stephaniae Japonicae (Caulis menispermi section) 40
Cork shape good fortune Man Radix Stephaniae Japonicae (Caulis menispermi section) 40
Right this Fu Shi Radix Stephaniae Japonicae of sieve (Caulis menispermi section) 40 that does not have hair
Coronule around Mo Shi certificate Hedychium coronarium Koenig (Zingiberaceae) 40
Medicinal Roskell ginger (Zingiberaceae) 30
Armadal curcuma (Zingiberaceae) 30
The concrete weight that is to be understood that each kind of plant can be determined according to the effectiveness of every kind of plant.
Propose the herbal-composition of a kind of prevention and treatment AIDS and the relevant syndrome of AIDS in another form more of the present invention, contain following dried plant material:
Medical herbs name class weight (milligram)
Vein shape Si Pulinshi Radix Stephaniae Japonicae (Caulis menispermi section) 55
Cork shape good fortune Man Radix Stephaniae Japonicae (Caulis menispermi section) 50
Right this Fu Shi Radix Stephaniae Japonicae of sieve (Caulis menispermi section) 50 that does not have hair
Coronule around Mo Shi certificate Hedychium coronarium Koenig (Zingiberaceae) 55
Medicinal Roskell ginger (Zingiberaceae) 45
Armadal curcuma (Zingiberaceae) 45
Preferably described compositions is a capsule form, and described capsule is preferably gelatine capsule.
Preferably described compositions is and the blended liquid form of syrup.
Propose the method for a kind of prevention of preparation and the herbal-composition of treatment AIDS and the relevant syndrome of AIDS in another form of the present invention, comprising:
(a) the dried plant material of following weight is made powder, dried plant material comprises substantially:
Medical herbs name class weight range (milligram)
Vein shape Si Pulinshi Radix Stephaniae Japonicae (Caulis menispermi section) 40-60
Cork shape good fortune Man Radix Stephaniae Japonicae (Caulis menispermi section) 40-60
Right this Fu Shi Radix Stephaniae Japonicae (Caulis menispermi section) 40-60 of sieve that does not have hair
Coronule around Mo Shi certificate Hedychium coronarium Koenig (Zingiberaceae) 40-60
Medicinal Roskell ginger (Zingiberaceae) 30-50
Armadal curcuma (Zingiberaceae) 30-50
(b) preparation contains in steps the medicine preparation of the powder of (a).
Preferably, vein shape Si Pulinshi Radix Stephaniae Japonicae, cork shape good fortune Man Radix Stephaniae Japonicae, right this Fu Shi Radix Stephaniae Japonicae of sieve that does not have hair, the gross weight around Mo Shi certificate Hedychium coronarium Koenig, medicinal Roskell ginger and Armadal curcuma compositions of coronule are not higher than 300 milligrams.
Preferably, described method comprises the compositions every day twice with above-mentioned amount to the patient (adult) of body weight below 60 kilograms or 60 kilograms, administration ante cibum.
Preferably, described method comprises to the patient of body weight 60-100 kilogram (adult) every day three times, and ante cibum is with described compositions administration.
Best mode of the present invention
Following detailed description is in order to understand principle of the present invention.But do not plan with these explanation restrictions the present invention.
Medical herbs mixture below finding after quite secular test and modification can successfully be treated AIDS patient.
The medical herbs name class
Vein shape Si Pulinshi Radix Stephaniae Japonicae (Caulis menispermi section)
Cork shape good fortune Man Radix Stephaniae Japonicae (Caulis menispermi section)
Right this Fu Shi Radix Stephaniae Japonicae (Caulis menispermi section) of sieve that does not have hair
Coronule around Mo Shi certificate Hedychium coronarium Koenig (Zingiberaceae)
Medicinal Roskell ginger (Zingiberaceae)
Armadal curcuma (Zingiberaceae)
Every kind of all fresh collection of medical herbs, wash, be cut into small pieces, dryly separate with all foreign body then.Pulverize together then into about 40-100 purpose powder, after drying in predetermined ratio each medical herbs of weighing.Should be appreciated that the extract that can adopt each target medical herbs, and prepare with known organic extracting method.
Resulting herbal powder compositions is charged in the hard gelatin capsule.Can adopt the mixture of described herbal-composition and suitable solid carrier, described carrier such as lactose, starch and lubricant (for example, magnesium stearate, calcium stearate) etc.Each capsule contains 300 milligrams the described herbal powder compositions of having an appointment.
The oral dose of test is 60 kilograms of body weight or following patient, every day twice, taking medicine before meal usefulness, whenever next capsule; And the patient of body weight 60-100 kilogram, every day three times, taking medicine before meal usefulness, whenever next capsule.
By the test of carrying out up to now, for general adult, the dose therapeutically effective of compositions is as follows at least:
Medical herbs name class minimum weight (milligram)
Vein shape Si Pulinshi Radix Stephaniae Japonicae (Caulis menispermi section) 40
Cork shape good fortune Man Radix Stephaniae Japonicae (Caulis menispermi section) 40
Right this Fu Shi Radix Stephaniae Japonicae of sieve (Caulis menispermi section) 40 that does not have hair
Coronule around Mo Shi certificate Hedychium coronarium Koenig (Zingiberaceae) 40
Medicinal Roskell ginger (Zingiberaceae) 30
Armadal curcuma (Zingiberaceae) 30
Also find, can increase by 20 milligrams for every kind of above-mentioned minimum weight of medical herbs.
Compositions is composed as follows in one first embodiment:
Medical herbs name class weight (milligram)
Vein shape Si Pulinshi Radix Stephaniae Japonicae (Caulis menispermi section) 55
Cork shape good fortune Man Radix Stephaniae Japonicae (Caulis menispermi section) 50
Right this Fu Shi Radix Stephaniae Japonicae of sieve (Caulis menispermi section) 50 that does not have hair
Coronule around Mo Shi certificate Hedychium coronarium Koenig (Zingiberaceae) 55
Medicinal Roskell ginger (Zingiberaceae) 45
Armadal curcuma (Zingiberaceae) 45
Gross weight 300
Treatment AIDS hospital with combination treatment of the present invention the patient who makes a definite diagnosis AIDS or HIV infection of development fully more than 100.Following chemical examination has all been carried out to all patients in front and back in treatment:
Serum globulin (Hb)
Leukocyte (WBC)
Platelet (Plt)
Polymorphonuclear cell (PMN)
Basophilic leukocyte (Bas)
Lymphocyte (Lymph)
Mononuclear cell (Mono)
CD4, CD8, CD4/CD8 ratio
Also carried out other health check-up.Find that through test most of patients has showed the improvement of health, and the symptom of most opportunistic infection or minimizing or obviously disappearance.Therefore, the medical herbs of about equivalent has provided the treatment advantage in the discovery compositions.

Claims (13)

1. the method for a prevention and treatment AIDS and the relevant syndrome of AIDS, comprise the step to animal or people's administering therapeutic effective dose of medicine thing preparation, described preparation contains the extract of following a kind of or several plants: vein shape Si Pulinshi Radix Stephaniae Japonicae, cork shape good fortune Man Radix Stephaniae Japonicae, right this Fu Shi Radix Stephaniae Japonicae of sieve that does not have hair, coronule around Mo Shi certificate Hedychium coronarium Koenig, medicinal Roskell ginger and Armadal curcuma.
2. the method that infects with the HIV of a kind of T lymphocytes in human body of preparation vitro inhibition infected by HIV and mononuclear phagocyte pedigree cell, described preparation contains the extract from one or more following plants basically: vein shape Si Pulinshi Radix Stephaniae Japonicae, cork shape good fortune Man Radix Stephaniae Japonicae, right this Fu Shi Radix Stephaniae Japonicae of sieve that does not have hair, coronule around Mo Shi certificate Hedychium coronarium Koenig, medicinal Roskell ginger and Armadal curcuma.
3. the compositions of a prevention and treatment AIDS and the relevant syndrome of AIDS, contain extract from one or more following plants: vein shape Si Pulinshi Radix Stephaniae Japonicae, cork shape good fortune Man Radix Stephaniae Japonicae, this Fu Shi Radix Stephaniae Japonicae of sieve right side that does not have hair, coronule around Mo Shi certificate Hedychium coronarium Koenig, medicinal Roskell ginger and Armadal curcuma.
4. the compositions of a prevention and treatment AIDS and the relevant syndrome of AIDS, comprise the acceptable herbal ingredients of treatment: respectively account for the 18.00-19.0% of gross weight vein shape Si Pulinshi Radix Stephaniae Japonicae, coronule around Mo Shi certificate Hedychium coronarium Koenig, the cork shape good fortune Man Radix Stephaniae Japonicae of 16.0-17.0%, right this Fu Shi Radix Stephaniae Japonicae of sieve that does not have hair and medicinal Roskell ginger, the Armadal curcuma of 14.5-15.5%.
5. the compositions of preventing and treating AIDS and the relevant syndrome of AIDS comprises the following dried plant material of selecting, and the selected ratio of various raw materials is:
Medical herbs name class minimum weight (milligram)
Vein shape Si Pulinshi Radix Stephaniae Japonicae (Caulis menispermi section) 40
Cork shape good fortune Man Radix Stephaniae Japonicae (Caulis menispermi section) 40
Right this Fu Shi Radix Stephaniae Japonicae of sieve (Caulis menispermi section) 40 that does not have hair
Coronule around Mo Shi certificate Hedychium coronarium Koenig (Zingiberaceae) 40
Medicinal Roskell ginger (Zingiberaceae) 30
Armadal curcuma (Zingiberaceae) 30
6. the compositions of a prevention and treatment AIDS and the relevant syndrome of AIDS comprises following dried plant material:
Medical herbs name class weight (milligram)
Vein shape Si Pulinshi Radix Stephaniae Japonicae (Caulis menispermi section) 55
Cork shape good fortune Man Radix Stephaniae Japonicae (Caulis menispermi section) 50
Right this Fu Shi Radix Stephaniae Japonicae of sieve (Caulis menispermi section) 50 that does not have hair
Coronule around Mo Shi certificate Hedychium coronarium Koenig (Zingiberaceae) 55
Medicinal Roskell ginger (Zingiberaceae) 45
Armadal curcuma (Zingiberaceae) 45
7. according to any one compositions of claim 3 to 6, it is characterized in that it being a kind of capsular form basically.
8. according to the compositions of claim 7, wherein said capsule is a kind of gelatine capsule.
9. according to any one compositions of claim 3 to 6, wherein said compositions is and the blended liquid form of syrup.
10. according to any one compositions of claim 3 to 9, it is characterized in that vein shape Si Pulinshi Radix Stephaniae Japonicae, cork shape good fortune Man Radix Stephaniae Japonicae, do not have hair right this Fu Shi Radix Stephaniae Japonicae of sieve, coronule around total mixed weight of the extract of Mo Shi certificate Hedychium coronarium Koenig, medicinal Roskell ginger and Armadal curcuma for not being higher than 300 milligrams.
11. the method for a prevention and treatment AIDS and the relevant syndrome of AIDS comprises that for body weight be patient below 60 kilograms or 60 kilograms, every day twice, uses the compositions administration according to any one of claim 3 to 10 ante cibum.
12. the method for a prevention and treatment AIDS and the relevant syndrome of AIDS comprises for body weight being the patient of 60-100 kilogram, every day three times, uses ante cibum according to any one compositions administration of claim 3 to 10.
13. the preparation of compositions method of preventing and treating AIDS and the relevant syndrome of AIDS comprises:
(a) the dried plant material of following weight is made powder, described dried plant material comprises substantially:
Medical herbs name class weight range (milligram)
Vein shape Si Pulinshi Radix Stephaniae Japonicae (Caulis menispermi section) 40-60
Cork shape good fortune Man Radix Stephaniae Japonicae (Caulis menispermi section) 40-60
Right this Fu Shi Radix Stephaniae Japonicae (Caulis menispermi section) 40-60 of sieve that does not have hair
Coronule around Mo Shi certificate Hedychium coronarium Koenig (Zingiberaceae) 40-60
Medicinal Roskell ginger (Zingiberaceae) 30-50
Armadal curcuma (Zingiberaceae) 30-50
(b) preparation contains in steps the pharmaceutical preparation of the powder of (a).
CN98813948A 1998-04-07 1998-04-07 Herbal composition for the prophylaxis and treatment of AIDS Pending CN1291103A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/AU1998/000236 WO1999051249A1 (en) 1998-04-07 1998-04-07 Herbal composition for the prophylaxis and treatment of aids

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Publication Number Publication Date
CN1291103A true CN1291103A (en) 2001-04-11

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KR (1) KR20010034764A (en)
CN (1) CN1291103A (en)
AU (1) AU760967B2 (en)
WO (1) WO1999051249A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002251801A1 (en) * 2001-01-19 2002-07-30 Johnson And Johnson Consumer Companies, Inc. Composition containing hedychium extract and use thereof
US20040052868A1 (en) 2002-09-12 2004-03-18 William Asiedu Composition treating for AIDS and associated conditions
US7160561B2 (en) 2003-05-19 2007-01-09 Amazon Biotech Inc. Herbal composition and method of treating HIV infection
WO2010112966A1 (en) * 2009-03-31 2010-10-07 Gbodossou Erick Vidjin Agnih Water-soluble antiviral product containing aframomum melegueta, for the treatment and prevention of acquired immunodeficiency syndrome (aids)
JP6198427B2 (en) * 2013-03-29 2017-09-20 小林製薬株式会社 Oral composition containing gelatin

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JP3002700B2 (en) * 1990-08-29 2000-01-24 化研生薬株式会社 Anti-AIDS virus agent
US5683698A (en) * 1996-08-02 1997-11-04 New England Deaconess Hospital Formulation for alleviating symptoms associated with arthritis

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KR20010034764A (en) 2001-04-25
WO1999051249A1 (en) 1999-10-14
JP2002510640A (en) 2002-04-09
AU6812598A (en) 1999-10-25

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