CN1287795A - Fodder additive contg. zinc hydroxy methionine and the prepn. method therefor - Google Patents
Fodder additive contg. zinc hydroxy methionine and the prepn. method therefor Download PDFInfo
- Publication number
- CN1287795A CN1287795A CN00113617A CN00113617A CN1287795A CN 1287795 A CN1287795 A CN 1287795A CN 00113617 A CN00113617 A CN 00113617A CN 00113617 A CN00113617 A CN 00113617A CN 1287795 A CN1287795 A CN 1287795A
- Authority
- CN
- China
- Prior art keywords
- zinc
- methionine
- hydroxy
- prepn
- hydroxy methionine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000654 additive Substances 0.000 title claims abstract description 14
- 230000000996 additive effect Effects 0.000 title abstract description 7
- LKEZBLSQCJEERD-WCCKRBBISA-N (2S)-2-(hydroxyamino)-4-methylsulfanylbutanoic acid zinc Chemical compound [Zn].ON[C@@H](CCSC)C(=O)O LKEZBLSQCJEERD-WCCKRBBISA-N 0.000 title 1
- 239000011701 zinc Substances 0.000 claims abstract description 22
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 claims abstract description 19
- 229910052725 zinc Inorganic materials 0.000 claims abstract description 19
- 239000007788 liquid Substances 0.000 claims abstract description 4
- 239000012266 salt solution Substances 0.000 claims abstract description 3
- 229930182817 methionine Natural products 0.000 claims description 11
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 claims description 10
- KFSJYZYQSZKRRQ-BYPYZUCNSA-N (2s)-2-(hydroxyamino)-4-methylsulfanylbutanoic acid Chemical compound CSCC[C@H](NO)C(O)=O KFSJYZYQSZKRRQ-BYPYZUCNSA-N 0.000 claims description 9
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims description 9
- 238000002360 preparation method Methods 0.000 claims description 6
- YVZATJAPAZIWIL-UHFFFAOYSA-M [Zn]O Chemical compound [Zn]O YVZATJAPAZIWIL-UHFFFAOYSA-M 0.000 claims description 4
- 229910017053 inorganic salt Inorganic materials 0.000 claims description 4
- 238000005119 centrifugation Methods 0.000 claims description 3
- 238000005406 washing Methods 0.000 claims description 3
- 241001465754 Metazoa Species 0.000 abstract description 13
- 239000003674 animal food additive Substances 0.000 abstract 2
- SDCGIYCBQZSYCZ-UHFFFAOYSA-K S(=O)(=O)([O-])CS(=O)(=O)[O-].O[Zn+2] Chemical compound S(=O)(=O)([O-])CS(=O)(=O)[O-].O[Zn+2] SDCGIYCBQZSYCZ-UHFFFAOYSA-K 0.000 abstract 1
- 230000009920 chelation Effects 0.000 abstract 1
- OWKLRGDFPHZYLS-UHFFFAOYSA-N hydroxymethanedisulfonic acid Chemical compound OS(=O)(=O)C(O)S(O)(=O)=O OWKLRGDFPHZYLS-UHFFFAOYSA-N 0.000 abstract 1
- 150000003751 zinc Chemical class 0.000 abstract 1
- 235000016804 zinc Nutrition 0.000 description 17
- 235000016709 nutrition Nutrition 0.000 description 6
- 230000035764 nutrition Effects 0.000 description 6
- 238000010521 absorption reaction Methods 0.000 description 3
- 239000007787 solid Substances 0.000 description 3
- 235000013619 trace mineral Nutrition 0.000 description 3
- 239000011573 trace mineral Substances 0.000 description 3
- 238000006243 chemical reaction Methods 0.000 description 2
- 230000006378 damage Effects 0.000 description 2
- 230000036039 immunity Effects 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 244000144977 poultry Species 0.000 description 2
- 239000002689 soil Substances 0.000 description 2
- 239000011782 vitamin Substances 0.000 description 2
- 229940088594 vitamin Drugs 0.000 description 2
- 229930003231 vitamin Natural products 0.000 description 2
- 235000013343 vitamin Nutrition 0.000 description 2
- 150000003722 vitamin derivatives Chemical class 0.000 description 2
- 208000035240 Disease Resistance Diseases 0.000 description 1
- 241000287828 Gallus gallus Species 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 230000002180 anti-stress Effects 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 230000037180 bone health Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 210000003746 feather Anatomy 0.000 description 1
- 230000037308 hair color Effects 0.000 description 1
- 230000002607 hemopoietic effect Effects 0.000 description 1
- 244000144980 herd Species 0.000 description 1
- 230000003053 immunization Effects 0.000 description 1
- 244000144972 livestock Species 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 235000015277 pork Nutrition 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 230000004584 weight gain Effects 0.000 description 1
- 235000019786 weight gain Nutrition 0.000 description 1
- 230000003245 working effect Effects 0.000 description 1
- RNZCSKGULNFAMC-UHFFFAOYSA-L zinc;hydrogen sulfate;hydroxide Chemical compound O.[Zn+2].[O-]S([O-])(=O)=O RNZCSKGULNFAMC-UHFFFAOYSA-L 0.000 description 1
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- Fodder In General (AREA)
Abstract
The invented feed additive, hydroxy zinc methionate, is prepared from liquid hydroxy methionic acid and inorganic zinc salt solution in the mole ratio of to 1-2 and through chelation unler 50-100 deg.c, pH 6-8 and normal pressure for 0.8 to 1.2 hr. The invented feed additive is high in biological efficacy can reduce the quantity of additive used, can provide microelement zinc and methinoine to animals.
Description
The present invention relates to a kind of methionine hydroxy zinc fodder additives and preparation method thereof.
Zinc is a kind of humans and animals trace elements necessary, is at present to adopt the inorganic salt of zinc as fodder additives, and animal absorbs must be by the various biological barrier, and its specific absorption is low, and addition is big, and biological value is low; Most of through the ight soil discharge, environment there is pollution; And these inorganic salt have destruction to VITAMIN isoreactivity material in the feed.The solid methionine(Met) of employing and inorganic zinc are also arranged jointly as additive, with the nutrition of additional methionine(Met), but the dissolving of solid methionine(Met) is relatively more difficult.
The object of the present invention is to provide a kind of animal absorption rate height, addition is little, the biological value height; Environmentally safe; Except that satisfying the nutrition of animal, also provide a kind of fodder additives and preparation method thereof of the nutrition of methionine(Met) for animal to trace element zinc.
The object of the present invention is achieved like this: fodder additives of the present invention is hydroxy methionine chelates of zinc (C
5H
8O
3Zn).
Its preparation method is as follows:
1, the inorganic salt solution of liquid hydroxy methionine and zinc is 1: 1～2 with mol ratio, and 50～100 ℃ of temperature, in the presence of sodium hydroxide, control pH value 6～8 reacted under the condition of normal pressure 0.8～1.2 hour, generated the hydroxy methionine chelates of zinc; Its reaction formula is as follows:
2, centrifugation, washing;
3, dry, pulverize, be packaged into finished product.
Because this chelating zinc is to absorb by the amino acid approach in livestock and poultry alimentary tract, speed is fast, specific absorption improves greatly, the biological value height, can reduce the consumption of additive; The micro-element nutrition of improving animal had good promoter action; Except that the nutrition of the trace element zinc that satisfies animal, also provide the nutrition of methionine(Met), so can promote the growth of animal for animal; Can also avoid the destruction of inorganic zinc to VITAMIN isoreactivity material in the feed; Can significantly improve the utilization ratio of feed.This hydroxy methionine inner complex has stable chemical structure, safety non-toxic, nonirritant.And, also can protect environment because the output of inorganic zinc is little in the ight soil.Use the liquid hydroxy methionine to overcome the difficult shortcoming of solid methionine(Met) dissolving.This additive can be widely used in various animals: as pig, fowl, aquatic animal etc.Test shows: add chelating zinc and can improve growth big porker order weightening finish 7.2%, feedstuff-meat ratio reduces by 3.3%, obviously improves carcass quality simultaneously.Add chelating zinc and improve day weight gain 5.8% in the broiler chicken feed, feed efficiency improves 2.1%, and makes bone health.For laying hen, chelating zinc can improve laying rate 9.8%, and zinc content improves more than 10% in the egg, and feedstuff-egg ratio reduces by 5.7%, and shell thickness and intensity all obviously improve, and can obviously strengthen the glossiness of bird hair.
Embodiment 1: methionine hydroxy zinc (C
5H
8O
3Zn) preparation and application:
85kg hydroxy methionine+80.5kg Zinc Sulphate Monohydrate+41kg98% technical pure sodium hydroxide is under 80 ℃ temperature of reaction, and regulating PH is 6.5, reacts 1 hour, obtains 128 kilograms of methionine hydroxy zincs, centrifugation, washing; Dry, pulverize, be finished product.Wherein zinc content is 21.5%, hydroxy methionine content 52.6%.
Feed herd boar with this additive 200～400 gram/tons, can promote growth, disease resistance enhancemen; Prolong boar and breed work-ing life; Feed suckling piglet with this additive 200～400 gram/tons, can help improving hemopoietic function and immunity function, improve anti-stress ability and immunizing power, promote growth, significantly improve the price of deed.The pork pig of engrossing then can promote growth, improves feedstuff-meat ratio, improves yellowish pink, makes the pigskin skin ruddy, the hair color light.Feed poultry the speed of growth is improved, feedstuff-meat ratio descends, and strengthens the feather glossiness, improves its stress ability, reduces mortality ratio.Feed aquatic animal, but strengthening immunity reduces incidence and mortality, promotes growth, reduce disease and take place, improve efficiency of feed utilization.
Claims (2)
1, a kind of fodder additives is characterized in that being hydroxy methionine chelates of zinc (C
5H
8O
3Zn).
2, a kind of preparation method of fodder additives as claimed in claim 1 is characterized in that may further comprise the steps:
(1), the inorganic salt solution of liquid hydroxy methionine and zinc is 1: 1～2 with mol ratio, 50～100 ℃ of temperature, in the presence of sodium hydroxide, pH value 6～8 reacted under the condition of normal pressure 0.8～1.2 hour, obtained methionine hydroxy zinc;
(2), centrifugation, washing;
(3), dry, pulverize, be packaged into finished product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN00113617A CN1112114C (en) | 2000-08-16 | 2000-08-16 | Fodder additive contg. zinc hydroxy methionine and the prepn. method therefor |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN00113617A CN1112114C (en) | 2000-08-16 | 2000-08-16 | Fodder additive contg. zinc hydroxy methionine and the prepn. method therefor |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1287795A true CN1287795A (en) | 2001-03-21 |
| CN1112114C CN1112114C (en) | 2003-06-25 |
Family
ID=4583384
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN00113617A Expired - Lifetime CN1112114C (en) | 2000-08-16 | 2000-08-16 | Fodder additive contg. zinc hydroxy methionine and the prepn. method therefor |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1112114C (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101704774B (en) * | 2009-10-30 | 2013-11-20 | 长沙兴加生物技术有限公司 | Hydroxyl nickel methionine and preparation method and application thereof |
| CN104304798A (en) * | 2014-10-30 | 2015-01-28 | 中国农业科学院北京畜牧兽医研究所 | Novel milk cow forage zinc-source additive adopting super-high chelation strength organic zinc |
| CN107095005A (en) * | 2017-03-25 | 2017-08-29 | 年付柱 | A kind of milk cow in lactation period concentrated feed and preparation method thereof |
| CN113261614A (en) * | 2021-05-21 | 2021-08-17 | 天宝动物营养科技股份有限公司 | Methionine hydroxy analogue-calcium phosphate and its feed preparation and preparation method |
-
2000
- 2000-08-16 CN CN00113617A patent/CN1112114C/en not_active Expired - Lifetime
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101704774B (en) * | 2009-10-30 | 2013-11-20 | 长沙兴加生物技术有限公司 | Hydroxyl nickel methionine and preparation method and application thereof |
| CN104304798A (en) * | 2014-10-30 | 2015-01-28 | 中国农业科学院北京畜牧兽医研究所 | Novel milk cow forage zinc-source additive adopting super-high chelation strength organic zinc |
| CN107095005A (en) * | 2017-03-25 | 2017-08-29 | 年付柱 | A kind of milk cow in lactation period concentrated feed and preparation method thereof |
| CN113261614A (en) * | 2021-05-21 | 2021-08-17 | 天宝动物营养科技股份有限公司 | Methionine hydroxy analogue-calcium phosphate and its feed preparation and preparation method |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1112114C (en) | 2003-06-25 |
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| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| ASS | Succession or assignment of patent right |
Owner name: CHANGSHA XINGJIA BIO-ENGINEERING CO., LTD Free format text: FORMER OWNER: HUANG YIQIANG Effective date: 20090508 |
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| C41 | Transfer of patent application or patent right or utility model | ||
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Effective date of registration: 20090508 Address after: Room 1, building 1017-1025, Xiang Zhong central 235, Wuyi Road, Hunan, Changsha Patentee after: Changsha Xingjia Bio-engineering Co.,Ltd. Address before: Room 708, Chi Chi Building, 340 Yanjiang Avenue, Changsha, Hunan Patentee before: Huang Yiqiang |
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Date of cancellation: 20111201 Granted publication date: 20030625 Pledgee: Bank of Changsha Limited by Share Ltd HSBC branch Pledgor: Changsha Xingjia Bio-engineering Co.,Ltd. Registration number: 2009430000557 |
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Denomination of invention: Fodder additive contg. zinc hydroxy methionine and the prepn. method therefor Effective date of registration: 20140718 Granted publication date: 20030625 Pledgee: Bank of Changsha Limited by Share Ltd HSBC branch Pledgor: Changsha Xingjia Bio-engineering Co.,Ltd. Registration number: 2014430000011 |
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Date of cancellation: 20160614 Granted publication date: 20030625 Pledgee: Bank of Changsha Limited by Share Ltd HSBC branch Pledgor: Changsha Xingjia Bio-engineering Co.,Ltd. Registration number: 2014430000011 |
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Granted publication date: 20030625 |