CN1280008A - Strong anti-oxidative composite capsule of grape seed extract OPC and its producing method - Google Patents
Strong anti-oxidative composite capsule of grape seed extract OPC and its producing method Download PDFInfo
- Publication number
- CN1280008A CN1280008A CN00121388A CN00121388A CN1280008A CN 1280008 A CN1280008 A CN 1280008A CN 00121388 A CN00121388 A CN 00121388A CN 00121388 A CN00121388 A CN 00121388A CN 1280008 A CN1280008 A CN 1280008A
- Authority
- CN
- China
- Prior art keywords
- seed extract
- grape seed
- opc
- vitamin
- capsule
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/074—Ganoderma
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/87—Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Alternative & Traditional Medicine (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
A strong antioxidant composite capsule in produced by using the materials including grape seed extract OPC, gynostemma pentaphylla general glycoside, glossy ganoderma spore powder and vitamin C and through the technological process of inspection, disinfection, sieving, stoving, weighing, mixing, capsulizing and other. It contains rich OPC polyphenols, saponins, polysaccharides, etc. and has several effective oxidants and several biological active components. Functional test shows that in has senility delaying, body's immunity regulating and other health-care functions.
Description
The present invention relates to a kind of medicinal preparation that contains the product of raw material or itself and not clear structure, relate in particular to a kind of medicine by plant and vitamin preparation.
Flavone in the medical evidence Semen Vitis viniferae is potent antioxidant; its oxidation resistance is 50 times of VE; 20 times of VC; its Oxidation also shows the attack of protecting the inside and outside biochemical composition of cell to avoid free radical; prolong cell survival, thereby can play the microcirculation improvement of defying age and vessel softening, reach cosmetology function; can also reduce erythrocytic aggregation, reduce the permeability of blood capillary.
Clinical trial has for many years been done in countries in the world, many medical and health-care products have been developed, not only price height of " Lean, Portugal " and Canadian " must precious element " of the U.S. but these products is arranged on the Chinese market now, and health-care effect nutrition face is narrower, only plays the high anti-oxidation effect but can not play many-sided effects such as immunologic function, defying age, cholesterol reducing, blood pressure lowering, blood fat reducing.
The objective of the invention is to: develop a kind of high anti-oxidation, raise immunity, blood pressure lowering, blood fat reducing, improve cardiac function, slow down aging, promotion human body metabolism, suppress a kind of capsule new drug of tumor, stimulating appetite and resistance.
The present invention is achieved in that capsule is made up of following composition by weight percentage:
Grape seed extract OPC 10-20%
Jiaogulanoside 10-30%
Ganoderma spore powder 20-40%
Vitamin C 20-40%
Its best is a Semen Vitis viniferae extract (OPC) 16%, and Herb Gynostemmae Pentaphylli is total 21%, Ganoderma spore powder 31.5%, vitamin C 31.5%.
Its production technology is: ingredient inspection (sample examination detects every index and will reach), and---sterilizing with C0-60 dosage 5GY radiation raw material,------------------------------pack---with C0-60 dosage 5GY radiation sterilization---puts in storage vertical material loading (evenly the back material loading reduces the material double differences) the check uniformity 15-30 minutes three-dimensional total mixing 80-100 orders impurity that sieves in check in packing in capsule fillings in weighing (batching) in oven dry (make water content up to standard).
The present invention adopts the high-quality Semen Vitis viniferae, and through the elite (procyanidolic oligomers OPC) that modern science is extracted, total saponin of Gold Theragran, Ganoderma spore powder, vitamin C are that feed purification forms.Contain abundant OPC Polyphenols, Saponin class, polysaccharide etc., multiple effective antioxidant is arranged, health-care effects such as multiple biological activity functional trial (through a plurality of big mice animal experiments) confirms to have slow down aging, adjusting body's immunity, nontoxic pair of effect.The mechanism of curing the disease of several raw materials of above-mentioned this is as described below:
Semen Vitis viniferae extract among the present invention confirms through France, the U.S., Canada and some European big medical institutions: having one's own knack aspect the canceration of control cellularity, growth of cancer cells is inhibited and is avoiding the complication of various cancers.
Jiaogulanoside is the good medicine of putative punish-old year chronic tracheitis, Herb Gynostemmae Pentaphylli has pharmacologically active widely because of it contains various chemical components, the confirmation that it is anticancer, defying age, resisting fatigue, antiulcer, analgesia, blood fat reducing, increase body hypoxia-bearing, the curative effect of paying aspects such as effect high temperature resistant and that prevent and treat diabetes, 17-hydroxy-11-dehydrocorticosterone have obtained pharmacological testing and clinical research has been widely used in clinical improvements cardiac function, Cure for insomnia, headache, symptom such as nervous to the positive performance myodyamia effect of cardiac muscle and central nervous system's significant inhibitory effect.
Ganoderma spore powder: modern scientific research is found, on the Ganoderma fibre substrate, mycelium can be secreted a large amount of enzymes, wherein mainly contain lipase, maltase, laccase, saccharase, amylase, saccharifying enzyme, Chymosin, cellulase, half cellulase, emulsus enzyme, tannase, urine enzyme, the white egg enzyme of pancreas, lipopeptid enzyme etc., these enzymes participate in human body substance metabolism and energy metabolism widely.Material fully absorbs and conversion, and for energy metabolism provides material base, the energy that redox discharged again for substance metabolism provides energy needed, makes whole metabolism that the balance that can reach new all be arranged.Find also that in addition Ganoderma contains various trace elements, as silver, boron, calcium, ferrum, potassium, phosphorus, sodium, manganese, zinc, germanium, bismuth etc., these trace element play an important role to the immunity and the resistance against diseases of enhancing body.These trace element are again the synthetic essential elements of human endocrine hormone simultaneously, and these endocrine hormones play very important regulatory role to the metabolism of body.
Vitamin c powder: play an important role in Cellular respiration, vitamin C participates in amino acid metabolism, neurotransmitter synthetic, matter is synthetic between collagen protein and histiocyte, can reduce the permeability of blood capillary, strengthen solidifying of blood, stimulate coagulation function, promote that ferrum absorbs at enteral, impel rate and blood-lipid decreased, increase resistance, participate in function of detoxification infecting, the effect that has antfhistamine effect and stop carcinogen (nitrosamine) to generate, clinical being used for: scorbutic prevention and treatment; Suitably replenishing of acute and chronic infectious disease with the enhancing body resistance, promotes sick the recovery and wound healing; Cardiogenic shock when taking place in Keshan disease patient, and available heavy dose is treated; Be used for liver cirrhosis, anxious quick dermatoses, aphtha, promotion wound healing etc., report in recent years: flu, some cancer, hyperlipidemia etc. are all had certain effect.
Vitamin C is for keeping one of indispensable vitamin of human body metabolism.Prevention vitamin C deficiency and treatment cause because of vitamin C is not enough that gingivitis, anemia, inappetence, malnutrition, resistance go down, growths stops and recovery after being ill etc., and are used for oral cavity, nose, kidney, uterus and other organ hemorrhages, various acute infectious disease etc.
Now with the high anti-oxidation of Semen Vitis viniferae extract (OPC) with increase the effect of immunologic function, the blood pressure lowering of Herb Gynostemmae Pentaphylli, blood fat reducing, improve cardiac function, function in delaying senility; The promotion human body metabolism of Ganoderma spore powder increases immunologic function, suppresses tumor; The nontoxic after testing pair effect of capsule of allocating development in one according to human needs is in proportion gathered in the effect of ascorbic appetite strengthening and resistance, the fullsized external product has stronger health-care effect in antioxidation, defying age, there is remarkable result aspects such as raise immunity and cholesterol reducing, blood pressure lowering, blood fat reducing.
In preparation during capsule: 1, get Semen Vitis viniferae extract total saponin of Gold Theragran, Ganoderma spore powder, four kinds of raw material sample examinations of vitamin C (except the mushroom) qualified after, go its outer package to send between buffering with C0-60 dosage 5GY radiation sterilization, disinfection by ultraviolet light takes out (80-100 mesh sieve) sieve that sieves the then oven drying that removes the solid impurity that may exist if moisture content exceeds standard after 6-10 hours.
2, treat that the moisture content fast measuring is qualified after, weigh batching is gone into three-dimensional mixer and is mixed its uniformity of pick test after 15-30 minutes, filled capsules polishing behind the quality certification.
3, capsule subpackage: packing bottle closure film, go its outer package to enter between buffering, after the Burdick lamp irradiation, enter the inner packing operation and use (inner packing is checked before sealing, packing, every bottle capsule quantity difference positive and negative one), seal spiral cover after packing is qualified.
4, packing labeling, vanning, check are got 1-2 bottles of qualified back joint sealings by every case, C0-60 dosage 5GY sterilization finished product warehouse-in.
5, working condition: production site should meet the pertinent regulations of " health food manufacturing enterprise GHP ".
6, process equipment: pulverizer, revolve the sieve that shakes, comminutor, drying bed, pelletizing machine, mixer, capsule filling machine, capsule, plastic bottle, sealing machine.
7, raw material production and quality standard: the blue general glycoside of Semen Vitis viniferae extract thigh glue, Ganoderma spore powder are dry fine powder, vitamin c powder, medicinal raw material, white powder.
| Material name | Kind | Production unit | The standard code |
| Semen Vitis viniferae extract | Natural | Penglai City's marine biochemical industry company limited | Q／PSHO11-98 |
| The blue general glycoside of thigh glue | Natural | The safe and comfortable pharmaceutical factory of Beijing Medical University | Defend medicine Z-03 |
| Ganoderma spore powder | Cultivate | General biotechnology development company of China Science and Technology Exchange Centre Haier of the Department of Science and Technology | Medicine strong (96) 0082 is defended in the capital |
| Vitamin c powder | Synthetic | Hebei Weierkang Pharmaceutical Co., Ltd | Standards of pharmacopoeia |
| Capsule | Suzhou capsule factory | Standards of pharmacopoeia |
The present invention is also available other factories of raw material of the above-mentioned unit of usefulness, but the regulation of essential conformance with standard code.
Embodiment: (claiming by 100g) formed 1 and forms 2 compositions, 3 compositions 4
Grape seed extract OPC 16 10 15 20
Jiaogulanoside 21 10 25 10
Ganoderma spore powder 31.5 40 30 30
Vitamin C 31.5 40 30 40
Claims (3)
1, a kind of strong anti-oxidative composite capsule of grape seed extract OPC is characterized in that: be made up of following composition by weight percentage:
Grape seed extract OPC 10-20%
Jiaogulanoside 10-30%
Ganoderma spore powder 20-40%
Vitamin C 20-40%
2, a kind of strong anti-oxidative composite capsule of grape seed extract OPC is characterized in that: be made up of following composition by weight percentage:
Grape seed extract OPC 16%
Jiaogulanoside 21%
Ganoderma spore powder 31.5%
Vitamin C 31.5%
3, the manufacture method according to claim 1 or 2 strong anti-oxidative composite capsule of grape seed extract OPC is characterized in that its operation is:
Ingredient inspection: take a sample, chemically examine, detect every index-with C0-60 dosage 5GY radiation
The raw material sterilization---sieve: 80-100 orders,---oven dry:---weighing---is three-dimensional total
Mix: 15-30 minutes,---check uniformity---vertical material loading: material loading evenly-
-capsule is filled, and------check: sampling check for quality---packing---is with C0-60 in packing
Dosage 5GY radiation sterilization---warehouse-in.
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN00121388A CN1111068C (en) | 2000-07-27 | 2000-07-27 | Strong anti-oxidative composite capsule of grape seed extract OPC and its producing method |
| AU2002214921A AU2002214921A1 (en) | 2000-07-27 | 2001-07-25 | A strong antioxidant composite capsule containing grape seed extract opc and process for producing the same |
| PCT/CN2001/001203 WO2002011744A1 (en) | 2000-07-27 | 2001-07-25 | A strong antioxidant composite capsule containing grape seed extract opc and process for producing the same |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN00121388A CN1111068C (en) | 2000-07-27 | 2000-07-27 | Strong anti-oxidative composite capsule of grape seed extract OPC and its producing method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1280008A true CN1280008A (en) | 2001-01-17 |
| CN1111068C CN1111068C (en) | 2003-06-11 |
Family
ID=4588769
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN00121388A Expired - Fee Related CN1111068C (en) | 2000-07-27 | 2000-07-27 | Strong anti-oxidative composite capsule of grape seed extract OPC and its producing method |
Country Status (3)
| Country | Link |
|---|---|
| CN (1) | CN1111068C (en) |
| AU (1) | AU2002214921A1 (en) |
| WO (1) | WO2002011744A1 (en) |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7037535B2 (en) | 2002-11-19 | 2006-05-02 | Kimberly-Clark Worldwide, Inc. | Method and composition for neutralizing house dust mite feces |
| CN100420391C (en) * | 2006-12-18 | 2008-09-24 | 东北虎药业股份有限公司 | Health-care food with anti-oxidation and lowering weight functions |
| US7585518B2 (en) | 2002-11-19 | 2009-09-08 | Kimberly-Clark Worldwide, Inc. | Products and methods for maintaining or increasing ceramide levels in skin |
| CN102511826A (en) * | 2011-12-29 | 2012-06-27 | 苏州爱斯欧蒂生物科技有限公司 | Lipid-lowering health care product and preparation method thereof |
| CN103156878A (en) * | 2013-04-11 | 2013-06-19 | 天津市园艺工程研究所 | Phellinus baumii polysaccharide and OPC (Oligomeric Proantho Cyanidins) slow-release micro-capsules |
| US8846116B2 (en) | 2003-07-22 | 2014-09-30 | Kimberly-Clark Worldwide, Inc. | Wipe and methods for improving skin health |
| CN105475999A (en) * | 2015-11-27 | 2016-04-13 | 杭州海王生物工程有限公司 | Composition with effects of resisting oxidation, improving liver damage and improving immunity |
| CN109007833A (en) * | 2018-08-22 | 2018-12-18 | 广州市顺芝堂生物科技有限公司 | It is a kind of to adjust the composition of immune function of human body, capsule and preparation method thereof |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6893641B2 (en) | 1999-10-12 | 2005-05-17 | Chee-Keung Chung | Ganoderma lucidum spores for treatment of autoimmune diseases |
| US6908614B2 (en) * | 1999-10-12 | 2005-06-21 | Chee-Keung Chung | Anti-aging/menopause symptoms relief using ganoderma lucidum spores |
| CN115444894B (en) * | 2022-09-24 | 2024-06-04 | 北京东方红航天生物技术股份有限公司 | Composition for early intervention of liver fibrosis, preparation method and preparation thereof |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61104772A (en) * | 1984-10-27 | 1986-05-23 | Osaka Chem Lab | Tea-like refreshing drink containing 'amachazuru' and its production |
| CN1083387A (en) * | 1993-05-31 | 1994-03-09 | 季永高 | " glossy ganoderma-gynostemma pentaphyllum " oral liquid |
| US5895652A (en) * | 1996-07-29 | 1999-04-20 | Longevity Institute International | Method of metabolic adjuvanation and cellular repair |
| TW542721B (en) * | 1997-08-06 | 2003-07-21 | Melaleuca Inc | Dietary supplements containing natural ingredients |
| EP1047392A4 (en) * | 1997-12-24 | 2004-10-06 | Shaklee Corp | Composition with high efficiency skin protection from damaging effects of ultraviolet light |
| KR20000034037A (en) * | 1998-11-27 | 2000-06-15 | 박인배 | Grape seed extract as tyrosinase inhibitor |
| CN1107110C (en) * | 1999-08-18 | 2003-04-30 | 孙传经 | Supercritical carbon dioxide extraction process of grape seed oil and cyanine oligomer |
-
2000
- 2000-07-27 CN CN00121388A patent/CN1111068C/en not_active Expired - Fee Related
-
2001
- 2001-07-25 WO PCT/CN2001/001203 patent/WO2002011744A1/en active Application Filing
- 2001-07-25 AU AU2002214921A patent/AU2002214921A1/en not_active Abandoned
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7037535B2 (en) | 2002-11-19 | 2006-05-02 | Kimberly-Clark Worldwide, Inc. | Method and composition for neutralizing house dust mite feces |
| US7585518B2 (en) | 2002-11-19 | 2009-09-08 | Kimberly-Clark Worldwide, Inc. | Products and methods for maintaining or increasing ceramide levels in skin |
| US7838025B2 (en) | 2002-11-19 | 2010-11-23 | Kimberly-Clark Worldwide, Inc. | Products and methods for maintaining or increasing ceramide levels in skin |
| US8846116B2 (en) | 2003-07-22 | 2014-09-30 | Kimberly-Clark Worldwide, Inc. | Wipe and methods for improving skin health |
| US10022308B2 (en) | 2003-07-22 | 2018-07-17 | Kimberly-Clark Worldwide, Inc. | Wipe and methods for improving skin health |
| CN100420391C (en) * | 2006-12-18 | 2008-09-24 | 东北虎药业股份有限公司 | Health-care food with anti-oxidation and lowering weight functions |
| CN102511826A (en) * | 2011-12-29 | 2012-06-27 | 苏州爱斯欧蒂生物科技有限公司 | Lipid-lowering health care product and preparation method thereof |
| CN103156878A (en) * | 2013-04-11 | 2013-06-19 | 天津市园艺工程研究所 | Phellinus baumii polysaccharide and OPC (Oligomeric Proantho Cyanidins) slow-release micro-capsules |
| CN105475999A (en) * | 2015-11-27 | 2016-04-13 | 杭州海王生物工程有限公司 | Composition with effects of resisting oxidation, improving liver damage and improving immunity |
| CN109007833A (en) * | 2018-08-22 | 2018-12-18 | 广州市顺芝堂生物科技有限公司 | It is a kind of to adjust the composition of immune function of human body, capsule and preparation method thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2002011744A1 (en) | 2002-02-14 |
| AU2002214921A1 (en) | 2002-02-18 |
| CN1111068C (en) | 2003-06-11 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104257887B (en) | A kind of composition for promoting lead discharging and its application | |
| CN103829238A (en) | Blood lipid lowering health food and preparation method thereof | |
| CN1111068C (en) | Strong anti-oxidative composite capsule of grape seed extract OPC and its producing method | |
| CN104206949A (en) | Composition for improving osteoporosis and increasing bone mineral density, preparation method of same and application of the same in preparation of health-caring product | |
| CN105105116A (en) | Health food with effects of relieving physical fatigue and enhancing immunity and preparation method of health food | |
| CN101991095A (en) | Health care product for improving sleep | |
| CN106578801A (en) | Comprehensive enzyme powder with hypoglycemic effect and preparation method thereof | |
| CN101297704B (en) | Health care food for protecting liver and manufacturing method thereof | |
| CN105053778A (en) | Aloe and xylooligosaccharide soft capsule capable of loosening bowel to relieve constipation and preparation method of aloe and xylooligosaccharide soft capsule | |
| CN1666660A (en) | Health food capable of postponing senility | |
| CN108713746A (en) | A kind of integration of drinking and medicinal herbs composition and its preparation method and application | |
| CN101129441B (en) | Rhodiola rosea capsule and its preparing method | |
| CN101664180A (en) | Health-care nutritional complexing agent with effect of and preparation method thereof | |
| CN105520132B (en) | A kind of composition and preparation method thereof with function of physical fatigue alleviation | |
| CN102430110B (en) | CAlprostadil composite medicament of compound fermented cordyceps sinensis powder and alprostadil composite drug | |
| CN106417817A (en) | Tea bag with effects of helping sleep and soothing nerves and preparation method thereof | |
| CN109010514A (en) | Composition, health care product and the preparation method of altitude sickness prevention | |
| CN104666823B (en) | A kind of regulation immunity, pharmaceutical composition of anti-aging and preparation method thereof | |
| CN101380102A (en) | Selenium rich pine pollen health food and preparation method thereof | |
| CN101015345A (en) | Health-care food with hypoxia-resistant and immunity-enhancing functions and its preparing process | |
| CN102146334A (en) | Donkey-hide gelatin wine | |
| CN103783397A (en) | Selenium enrichment eucommia ulmoides fine dried noodles and preparation technology thereof | |
| CN1057683C (en) | Compound selenic-garlic health medicine and its preparation method | |
| CN100377661C (en) | Process for preparing micrometer sugared shentiandiyinluyi, kidney invigorating and fatigue reducing wine | |
| CN107412283A (en) | A kind of three high drop composition containing Agricus blazei extract and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C06 | Publication | ||
| PB01 | Publication | ||
| ASS | Succession or assignment of patent right |
Owner name: SHANGHAI BEIYIDA BIOLOGY SCIENCE CO., LTD. Free format text: FORMER OWNER: BEIJIDA MEDICAL SCIENCE AND TECHNOLOGY CO., LTD., BEIJING Effective date: 20020327 |
|
| C41 | Transfer of patent application or patent right or utility model | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20020327 Address after: 1009, room 841, No. 200040 middle Yanan Road, Shanghai Applicant after: Beiyida Medical Science and Technology Co., Ltd., Shanghai Address before: 100083 No. 38, Haidian District, Beijing, Xueyuan Road Applicant before: Beijida Medical Science and Technology Co., Ltd., Beijing |
|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C19 | Lapse of patent right due to non-payment of the annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |