CN1265315A

CN1265315A - Medicine mixture with rhubarb and other herbal medicine material

Info

Publication number: CN1265315A
Application number: CN 00101213
Authority: CN
Inventors: 马骏瑞
Original assignee: Individual
Current assignee: Individual
Priority date: 2000-01-02
Filing date: 2000-01-02
Publication date: 2000-09-06

Abstract

The medicine mixture for treating pulmonary tuberculosis is new Chinese medicine. Twenty-six kinds of Chinese medicinal materials including chaulmoogra, etc. are produced into aerosol and vapor inhalation, which may reach the lesion part of lung directly via respiratory tract medication, and twenty-five kinds of Chinese medcinal materials without chaulmoogra are produced into oral medicine, which is taken orally to raise the medicine concentration insie body and to kill tubercle bacillus. The medicine can reach satisfied cure effect, especially for intractable pulmonary tuberculosis. In addition, the medicine may be also used to treat the infection of upper respiratory tract, bronchitis, pertussis, pneumonia and other diseases of respiratory system.

Description

Medicine mixture with rhubarb and other herbal medicine material

The present invention is a kind of pulmonary's Chinese medicine compound new drug lungy that is used for the treatment of, and belongs to tcm field new Chinese medicine class.

The pulmonary of treatment at present tuberculosis mainly adopts the anti-mycobacterium tuberculosis chemotherapy.Though can treat pulmonary's tuberculosis more effectively, but still it is few to exist the anti-mycobacterium tuberculosis types of drugs, easy drug-fast defective.Particularly control the patient again, lack effective treatment means drug-fast.

The objective of the invention is: a kind of pulmonary's Chinese medicine compound new drug lungy that is used for the treatment of is provided, and it has very strong inhibition and kills the tubercule bacillus effect, also has simultaneously to be difficult for producing chemical sproof advantage.With existing anti-mycobacterium tuberculosis chemicals contract, treatment pulmonary tuberculosis, comparable list shortens the course of treatment greatly with the faster symptom of improving of chemotherapy, reduces relapse rate, makes the faster recovery from illness of patient.Particularly, as main treatment means, can obtain satisfied curative effect with the present invention to the drug resistance that is difficult at present the treat people that cures the disease again.

The present invention is achieved in that and uses through modern pharmacological research, to the tubercule bacillus antibacterial action, than the strong Semen Hydnocarpi more than 100 times of phenol as principal agent.With through modern pharmacological research, tubercule bacillus there are stronger inhibiting Rhizoma Coptidis, the Radix Stemonae, three kinds of medicines of Cordyceps as accessory drugs.With through modern pharmacological research, there are obvious inhibiting Radix Scutellariae, Flos Lonicerae, Fructus Forsythiae, Herba Violae, Flos Chrysanthemi, the Rhizoma Anemarrhenae, Radix Salviae Miltiorrhizae, Fructus Mume, Semen Ginkgo, the Pseudobulbus Bletillae (Rhizoma Bletillae), Rhizoma Polygonati, Radix Glycyrrhizae, 13 kinds of medicines of Radix Polygoni Multiflori to make adjuvant drug to tubercule bacillus.With through modern pharmacological research, the effective Spica Prunellae of tubercule bacillus, Radix Cirsii Japonici, Cacumen Platycladi, Radix Sanguisorbae, the Radix Angelicae Dahuricae, Herba Andrographis, Herba Houttuyniae, Herba Artemisiae Scopariae, nine kinds of medicines of Cortex Magnoliae Officinalis are made messenger drug, form a Chinese medicine compound new drug that tubercule bacillus is had very strong inhibition killing action jointly.Above 26 kinds of medicines are extracted respectively, extract, be refined into aerosol, steam inhalant,, can make the medicine pulmonary lesion position of going directly, treat pulmonary's tuberculosis medicine very effectively through the direct inhalation of respiratory tract.Simultaneously, also, make tablet, capsule, dissolved granule, concentrated oral liquid, fluid extract, cooperate oral administration all the other the 25 kinds of medicines except that unsuitable oral Semen Hydnocarpi, in the intravital valid density of patient, more effectively treat pulmonary's tuberculosis with further raising the present invention.In addition, because the multiple medicine that the present invention adopts all has good broad-spectrum antibacterial action, what have also has different heat-clearing and toxic substances removing, cough-suppressing phlegm-dispelling functions respectively, also can be widely used in respiratory system diseases such as treatment upper respiratory tract infection, bronchitis, pertussis, pneumonia.

Owing to adopt such scheme, overcome that Chinese medicine Semen Hydnocarpi toxicity is big, oral dose is little, be difficult in blood, reaching the difficult problem of higher concentration, kill the Chinese medicine Semen Hydnocarpi that tubercule bacillus acts on having brute force, at first be used for the treatment of pulmonary's tuberculosis.Because Semen Hydnocarpi is stronger more than 100 times than phenol to the antibacterial action of tubercule bacillus, tubercule bacillus is had very intensive direct killing action, through the direct inhalation of respiratory tract, can make the medicine pulmonary lesion position of going directly.Not only can directly kill the tubercule bacillus in the patient respiratory road, but also can absorb the drug, at the higher drug level of the local formation of lung lesion by the about 100 square metres huge area of lung vesicle.Equally, though contained berberine has good inhibitory effect to tubercule bacillus in the Rhizoma Coptidis, concentration can not reach the treatment desired concn in the oral bleeding from anus.By the direct inhalation of respiratory tract, can make also that contained berberine part in lungs reaches higher concentration in the Rhizoma Coptidis, thereby tubercule bacillus is played the good restraining effect.Other 24 kinds auxilliary, assistants, messenger drug have in various degree inhibitory action to tubercule bacillus portion, by the direct administration of respiratory tract, can reach higher effective concentration in the lung lesion part, cooperate principal agent to bring into play better anti-mycobacterium tuberculosis effect jointly.Can kill the tubercule bacillus on pulmonary's tuberculose focus directly, up hill and dale.Pulmonary's tuberculosis is played better therapeutical effect.

Claims

1, a kind of pulmonary's medicine mixture with rhubarb and other herbal medicine material lungy that is used for the treatment of, it is characterized in that: use the tubercule bacillus antibacterial action is made principal agent than the strong Semen Hydnocarpi more than 100 times of phenol, with tubercule bacillus there being stronger inhibiting Rhizoma Coptidis, the Radix Stemonae, three kinds of medicines of Cordyceps are as accessory drugs, with tubercule bacillus there being obvious inhibiting Radix Scutellariae, Flos Lonicerae, Fructus Forsythiae, Herba Violae, Flos Chrysanthemi, the Rhizoma Anemarrhenae, Radix Salviae Miltiorrhizae, Fructus Mume, Semen Ginkgo, the Pseudobulbus Bletillae (Rhizoma Bletillae), Rhizoma Polygonati, Radix Glycyrrhizae, Radix Polygoni Multiflori, 13 kinds of medicines are made adjuvant drug, with through modern pharmacological research, to the effective Spica Prunellae of tubercule bacillus, Radix Cirsii Japonici, Cacumen Platycladi, Radix Sanguisorbae, the Radix Angelicae Dahuricae, Herba Andrographis, Herba Houttuyniae, Herba Artemisiae Scopariae, nine kinds of medicines of Cortex Magnoliae Officinalis are as messenger drug, it is new drug that one of common composition has very strong inhibiting middle recurrence due to taking drug to tubercule bacillus, be mainly used to make aerosol, the steam inhalant, through the direct inhalation of respiratory tract, be used for making tablet simultaneously, capsule, dissolved granule, concentrated oral liquid, fluid extract cooperates oral administration, to assist to improve medicine in the intravital concentration of patient (in the oral agents without Semen Hydnocarpi).

2, medicine mixture with rhubarb and other herbal medicine material according to claim 1 is characterized in that: use the tubercule bacillus antibacterial action Semen Hydnocarpi stronger 100 times than phenol made principal agent, make aerosol, steam inhalant.

3, medicine mixture with rhubarb and other herbal medicine material according to claim 1, its spy is just: with Rhizoma Coptidis, the Radix Stemonae, Cordyceps, Radix Scutellariae, Flos Lonicerae, Fructus Forsythiae, Herba Violae, Flos Chrysanthemi, the Rhizoma Anemarrhenae, Radix Salviae Miltiorrhizae, Fructus Mume, Semen Ginkgo, the Pseudobulbus Bletillae (Rhizoma Bletillae), Rhizoma Polygonati, Radix Glycyrrhizae, Radix Polygoni Multiflori, Spica Prunellae, Radix Cirsii Japonici, Cacumen Platycladi, Radix Sanguisorbae, the Radix Angelicae Dahuricae, Herba Andrographis, Herba Houttuyniae, Artemisia anethoicles Mattf, 25 kinds of medicines of Cortex Magnoliae Officinalis, cooperate the principal agent strong wind in common composition compound recipe, make aerosol, steam inhalant.

4, medicine mixture with rhubarb and other herbal medicine material according to claim 1, it is characterized in that:, make tablet, capsule, dissolved granule, concentrated oral liquid, fluid extract with Rhizoma Coptidis, the Radix Stemonae, Cordyceps, Radix Scutellariae, Flos Lonicerae, Fructus Forsythiae, Herba Violae, Flos Chrysanthemi, the Rhizoma Anemarrhenae, Radix Salviae Miltiorrhizae, Fructus Mume, Semen Ginkgo, the Pseudobulbus Bletillae (Rhizoma Bletillae), Rhizoma Polygonati, Radix Glycyrrhizae, Radix Polygoni Multiflori, Spica Prunellae, Radix Cirsii Japonici, Cacumen Platycladi, Radix Sanguisorbae, the Radix Angelicae Dahuricae, Herba Andrographis, Herba Houttuyniae, Artemisia anethoicles Mattf, 25 kinds of medicines of Cortex Magnoliae Officinalis.