CN104208448A - Lymphoid tuberculosis blood circulation invigorating hardness softening agent and preparation method - Google Patents
Lymphoid tuberculosis blood circulation invigorating hardness softening agent and preparation method Download PDFInfo
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Abstract
The invention discloses a lymphoid tuberculosis blood circulation invigorating hardness softening agent and a preparation method. The lymphoid tuberculosis blood circulation invigorating hardness softening agent is prepared, by weight, by the following raw materials: Chinese honey locust peels 5-12 parts, rhizoma gastrodiae 4-7 parts, cirsium japonicum 3-9 parts, cutworm 5-15 parts, all grass or root of common calanthe 6-10 parts, annual fleabane herb 6-9 parts, polygonum multiflorum 6-15 parts, jenkine dendrobium 18-32 parts, selfheal 15-25 parts, fructus forsythia 6-12 parts, longstipe gynostemma herb 5-10 parts and silkworm larva 3-6 parts. The lymphoid tuberculosis blood circulation invigorating hardness softening agent has the effects of resolving softening hardness to dissipate stagnation and invigorating blood circulation to dissipate stagnation, further has the prevention effect while having treatment effect on lymphoid tuberculosis and is reliable and fixed in treatment effect.
Description
Technical field
The present invention relates to tcm field, particularly relate to a kind of scrofulous movable blood soft hard agent and preparation method thereof for the treatment of.
Background technology
Lymphoid tuberculosis, the traditional Chinese medical science is referred to as scrofula, is the malicious block organization that is embodied in flesh table, is that the scorchingly hot poison cohesion of the expectorant institute by liver lung two aspects is become.Doctor trained in Western medicine refers to, thereby specialize in human body in detoxicating virus killing, protects blood vessel, and the lymphsystem of tissue, meets with outside ex vivo and cannot remove the toadstool of killing, and condenses and assemble the malignant tumor of Yu Ji table organization formation.The name of " scrofula " first appeared in two thousand years before a < < Huang di's Canon of Medicine > > Ling Shu Miraculous Pivot or Divine Axis cold and heat piece of writing: the core piece that " cold and heat scrofula; be neck axil person " can lay one's hand on and differ in size between cervical region skin and flesh, its little person is scrofula, large person is scrofula, because it is contacted mutually, coherent as beading, therefore be referred to as scrofula.Primary disease feature, from the beginning of as bean, feels no pain, and increases gradually, innumerable as beading, and while becoming pus, color of the leather transfers to dark redly, and after bursting, pus is rare clearly, and often this heals, and that is broken, formation sinus tract, and shape is as mouse hole.Therefore among the people, be commonly called as " lymphoid tuberculosis ".Lymphoid tuberculosis with cervical region for the most common, how in cervical region one side or bilateral, to grow pimple, grow up gradually, superficial, push slip, without obvious tenderness, if passive protective physical fitness is low, increase gradually, skin purpling, final ulceration flowing water sample pus is also discharged the cheesy pus of yellow turbid sample, repeatedly fester few, the whole body poisoning symptom such as part patient can have low grade fever, robber, antiperspirant inappetence, become thin.Cervical lymph node core also can merge mediastinum hilus pulumonis portion, axillary region, pars inguinalis lymphoid tuberculosis.Lymphoid tuberculosis pathogenic factor has two kinds: a kind of is that tubercule bacillus infects on oral cavity and the nasopharynx part primary tumor that especially tonsil gland causes by upper respiratory tract or with food.Tailing edge lymphatic vessel arrives the shallow deep layer lymph node of cervical region.Each position mostly is one-sided property lymph node, gets involved pharyngeal.The lymphoid tuberculosis of getting involved after sick above absorption of repeating transmission still continues development formation cold abscess or ulcer.Another kind is that in the rear blood of primary tuberculosis infection, tubercule bacillus enters inside neck lymph node with blood, causes the tuberculosis of cervical lymph nodes; Can also infect from waist and belly lymph, then draw and deep lymph node group secondary infection, comparatively common in tuberculosis of cervical lymph nodes morbidity.
Western medical treatment medicine has isoniazid, sodium aminosalicylate, rifampicin and streptomycin etc.For cold abscess secondary pyogenic infection person, need incision and drainage in advance, after infection control, row curettage more if desired.The traditional Chinese medical science thinks, scrofula incidence is many to be pented up through wind heat gas poison and formed by three warmers, liver, gallbladder etc., and Liver and kidney two is through deficiency of both QI and blood, moving in asthenic fire due to, can be divided into acute, chronic two classes.Acute many because of affection due to external wind and heat, in accumulate expectorant poison and send out; More than chronic, because of the stagnation of QI, void, hinder and send out.The methods that adopt acupuncture and medicine partner treatment more.
Publication number CN 103638157A(application number 201310619281.4) Chinese patent literature discloses a kind of scrofulous Chinese medicine formula for the treatment of, comprising: Semen Ginkgo core 12g, Caulis Cucurbitae 14g, Radix Rubiae 15g, Herba Spilanthis Acmellae 8g, Radix Gentianae Macrophyllae 3g.Publication number CN 103611060A(application number 201310518997.5) Chinese patent literature discloses a kind of scrofulous Chinese medicine composition for the treatment of, the weight portion of constitutive material is: Folium Mahoniae 10-12, Fructus Forsythiae 3-5, Herba Schizonepetae 2-4, Fructus Arctii 5-8, Folium Isatidis 2-4, Herba Taraxaci 1-3, Pollen Typhae 3-5, Herba Violae 1-2, Radix Cirsii Japonici 1-2, Rhizoma Curcumae 6-8, Olibanum (processed) 2-4, Radix Semiaquilegiae 2-3, tetrastigma hemsleyanum 1-2, Rhizoma Smilacis Glabrae 5-7, Herba cynodontis 2-4, Herba Rubi parvifolii 1-3, Folium Ricini 6-8, Herba seu Radix Calanthes 2-3, Radix Et Rhizoma Fagopyri Tatarici 10-12, Radix Tylophorae arenicolae 2-4, pumpkin peel 10-15 and Indigo Naturalis 2-4.Publication number CN 103381229A(application number 201310259621.7) Chinese patent literature discloses scrofulous Chinese medicine for the treatment of and preparation method thereof, and it is comprised of Venenum Bufonis, orange peel, Flos Carthami, Borneolum Syntheticum, Cortex ulmi pumilae, Alumen, Rhizoma Arisaematis, Squama Manis, Myrrha, Periostracum Serpentis, Air Bladder pseudosciaenae seu Acipenser, Herba euphorbiae lunulatae, slug, Semen Ricini, Scorpio, Flos Rosae Rugosae, Herba ixeritis debilis, Radix Calystegiae sepii, Flos edgeworthiae, black pepper, Flos Sophorae and Herba Taraxaci etc.
At present, some traditional Chinese medical science formulas are failed completely in conjunction with lymphoid tuberculosis pathogeny, and disease and Chinese medicine principle are treated this disease, are therefore difficult to reach healing object, have even likely incured loss through delay patient's the optimal treatment phase, make patient's aggravation.
Summary of the invention
For prior art weak point, the object of this invention is to provide a kind of Chinese medicine preparation that treatment lymphoid tuberculosis is had to outstanding curative effect, i.e. lymphoid tuberculosis movable blood soft hard agent.
Technical scheme of the present invention is:
The agent of lymphoid tuberculosis movable blood soft hard, is prepared from by following bulk drugs, is weight portion: Fructus Gleditsia veneer 5-12, Rhizoma Gastrodiae 4-7, Radix Cirsii Japonici 3-9, Stachys geobombycis C. Y. Wu 5-15, Herba seu Radix Calanthes 6-10, Herba Erigerontis Annui 6-9, Radix Polygoni Multiflori 6-15, calls the bright 18-32 of frightening together, Spica Prunellae 15-25, Fructus Forsythiae 6-12, long stalk Herba lysimachiae capillipedis 5-10, Bombyx Batryticatus 3-6.
In preferred scheme, Fructus Gleditsia veneer 7-10, Rhizoma Gastrodiae 5-6, Radix Cirsii Japonici 5-7, Stachys geobombycis C. Y. Wu 8-12, Herba seu Radix Calanthes 7-9, Herba Erigerontis Annui 7-8, Radix Polygoni Multiflori 8-13, calls the bright 23-27 of frightening together, Spica Prunellae 18-22, Fructus Forsythiae 8-10 part, long stalk Herba lysimachiae capillipedis 6-9, Bombyx Batryticatus 4-5.
Be more preferably, Fructus Gleditsia veneer 8.5, Rhizoma Gastrodiae 5.5, Radix Cirsii Japonici 6, Stachys geobombycis C. Y. Wu 10, Herba seu Radix Calanthes 8, Herba Erigerontis Annui 7.5, Radix Polygoni Multiflori 10.5, calls together and brightly frightens 25, Spica Prunellae 20, Fructus Forsythiae 9, long stalk Herba lysimachiae capillipedis 7.5, Bombyx Batryticatus 4.5.
The present invention also provides aforementioned medicament has been made to pharmaceutically acceptable decoction, powder, pill and thick paste agent.
The preparation method of described decoction is as follows:
(1) wheat bran is spread in heat pot, waits cigarette and rise, pour Bombyx Batryticatus into, fry to yellow, take out sieve and remove wheat bran, cool, pulverized 100 order-180 orders (preferably 140 orders) sieve, must fry Bombyx Batryticatus powder, standby;
(2) Radix Cirsii Japonici is wrapped up to three layers with coarse toilet paper by medicine, put into water drenched, put in pot interior-heat sand and simmer to sallow, take out, cool, must simmer Radix Cirsii Japonici, standby;
(3) by Fructus Gleditsia veneer, Rhizoma Gastrodiae, Stachys geobombycis C. Y. Wu, Herba seu Radix Calanthes, Herba Erigerontis Annui, Radix Polygoni Multiflori, call together brightly frighten, Spica Prunellae, Fructus Forsythiae, long stalk Herba lysimachiae capillipedis put into marmite together with simmering Radix Cirsii Japonici with gained in step (2), soak 4-6 hour (preferably 5 hours), the water surface exceeds 3 centimetres of medical materials, then intense fire turns at a simmer after boiling, filter, decoct altogether twice, slow fire boiling 40-80 minute for the first time (preferably 60 minutes), slow fire boiling 40-60 minute for the second time (preferably 50 minutes), merge filtrate twice, heating is concentrated into the amount of Ligularia nelumbifolia(Bur. et Franch.) Hand.-Mazz., obtains medicinal liquid, standby;
(4) step (1) and (3) gained are fried to Bombyx Batryticatus powder and medicinal liquid mix homogeneously, obtain lymphoid tuberculosis movable blood soft hard agent decoction.
The preparation method of described powder is:
(1) wheat bran is spread in heat pot, waits cigarette and rise, pour Bombyx Batryticatus into, fry to yellow, take out sieve and remove wheat bran, cool, must fry Bombyx Batryticatus, standby;
(2) by Fructus Gleditsia veneer, Rhizoma Gastrodiae, Radix Cirsii Japonici, Stachys geobombycis C. Y. Wu, Herba seu Radix Calanthes, Herba Erigerontis Annui, Radix Polygoni Multiflori, call together brightly frighten, Spica Prunellae, Fructus Forsythiae, long stalk Herba lysimachiae capillipedis and fry Bombyx Batryticatus and make super cell grade 380 object micropowders, obtain powder.
The preparation method of described pill is:
(1) wheat bran is spread in heat pot, waits cigarette and rise, pour Bombyx Batryticatus into, fry to yellow, take out sieve and remove wheat bran, cool, must fry Bombyx Batryticatus, standby;
(2) by Fructus Gleditsia veneer, Rhizoma Gastrodiae, Radix Cirsii Japonici, Stachys geobombycis C. Y. Wu, Herba seu Radix Calanthes, Herba Erigerontis Annui, Radix Polygoni Multiflori, call together brightly frighten, Spica Prunellae, Fructus Forsythiae, long stalk Herba lysimachiae capillipedis and fry Bombyx Batryticatus co-grinding and cross 120 mesh sieves, obtain medicated powder, standby;
(3) get it filled powder and Mel is mixed and made into honeyed pill, and the size of ball is 2-3mm.
Described movable blood soft hard agent, the mass ratio of step (3) Chinese medicine powder and Mel is 5:4.
The preparation method of described thick paste agent is:
(1) wheat bran is spread in heat pot, waits cigarette and rise, pour Bombyx Batryticatus into, fry to yellow, take out sieve and remove wheat bran, cool, pulverized 100 order-180 orders (preferably 140 orders) sieve, must fry Bombyx Batryticatus powder, standby;
(2) Radix Cirsii Japonici is wrapped up to three layers with coarse toilet paper by medicine, put into water drenched, put in pot interior-heat sand and simmer to sallow, take out, cool, must simmer Radix Cirsii Japonici, standby;
(3) by Fructus Gleditsia veneer, Rhizoma Gastrodiae, Stachys geobombycis C. Y. Wu, Herba seu Radix Calanthes, Herba Erigerontis Annui, Radix Polygoni Multiflori, call bright frightening together, Spica Prunellae, Fructus Forsythiae, long stalk Herba lysimachiae capillipedis is put into marmite together with simmering Radix Cirsii Japonici with gained in step (2), soak 4-6 hour (preferably 5 hours), the water surface exceeds 3 centimetres of medical materials, then intense fire turns at a simmer after boiling, filter, decoct altogether twice, slow fire boiling 40-80 minute for the first time (preferably 60 minutes), slow fire boiling 40-60 minute for the second time (preferably 50 minutes), merge filtrate twice, it is 1.18-1.22(preferably 1.20 that heating is concentrated into relative density) clear paste of (60 ℃), standby,
(4) step (1) and (3) gained are fried to Bombyx Batryticatus powder and clear paste mix homogeneously, obtain thick paste agent.
The application of movable blood soft hard agent described in the present invention also provides when the medicine of preparation treatment lymphoid tuberculosis and lymphadenectasis.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
Fructus Gleditsia veneer: base is former: be root bark or the peel of stem of the plant Fructus Gleditsia of pulse family Gleditsia.Nature and flavor: pungent, temperature, nontoxic.Effect: the effects such as detoxicating and resolving stagnation of pathogens, wind dispelling insecticide, cure mainly: innominate toxic swelling, scabies, malignant boil, lymphoid tuberculosis, rheumatic ostalgia etc.
Rhizoma Gastrodiae: base is former: the tuber of Wei Tian section Gastrodia plant Rhizoma Gastrodiae.Composition: Rhizoma Gastrodiae contains phenols: Gastrodine claims gastrodine, gastrodioside, 4-ethoxymethyl phenol, hydroxy benzaldehyde, 3,4-4-dihydroxy benzaldehyde; Aromatic compound: 4-acrinyl methyl ether etc.The property of medicine: sweet, pungent, flat.Return Liver Channel.Function cures mainly: relieving spasm by subduing liver-wind, suppressing the hyperactive liver sun, dispelling wind and removing obstruction in the collateral.Cure mainly anxious chronic infantile convulsion, tic contracture, tetanus, dizzy, headache, hemiplegia, limb fiber crops, rheumatic arthralgia.
Radix Cirsii Japonici (preferably cirsii japonici,radix): nature and flavor: sweet cool.Enter liver, spleen channel.Effect: cooling blood for hemostasis, blood stasis dispelling eliminating carbuncle.Cure mainly: the haematemesis due to heat in blood, epistaxis, hematuria, stranguria with blood, metrorrhagia, incised wound are hemorrhage etc., and hemorrhoidal hamorrhage, acute appendicitis, sore swollen toxin, treatment skin ulcer etc.
Stachys geobombycis C. Y. Wu: call native Cordyceps, white Cordyceps, tapeworm grass, pulmonary tuberculosis careless.Base is former: Labiatae betony Stachys geobombycis C. Y. Wu, and sweet with the tuber flavor efficacy that is used as medicine, flat.The lung moistening of function kidney tonifying, nourishing YIN and supplementing blood, clearing heat and relieving fidgetness.Be applicable to pulmonary tuberculosis cough, deficiency of the lung asthma, haematemesis, night sweat, anemia, infantile malnutrition.
Herba seu Radix Calanthes: base is former: be orchid calanthe herb or rhizome.Nature and flavor: pungent; Micro-hardship; Be slightly cold.Gui Jing: liver; Spleen channel function cures mainly: heat-clearing and toxic substances removing; Promoting blood circulation and stopping pain.Main scrofula infections; Carbuncle; Laryngopharynx swelling and pain; Hemorrhoid; Rheumatic arthralgia; Traumatic injury.
Herba Erigerontis Annui: base is former: be the herb of Compositae Herba Erigerontis aceris platymiscium Herba Erigerontis Annui.Composition: herb is containing pyromeconic acid.Flower contains pyrite constituents: Quercetin, apigenin-7-glucuronide, apigenin etc.The property of medicine: sweet, bitter, cold.Function cures mainly: removing toxic substances, hemostasis, helps digestion, preventing the attack (or recurrence) of malaria.Cure mainly lymphadenitis, gingivitis, venom, hematuria, dyspepsia, gastroenteritis, malaria.
Radix Polygoni Multiflori: nature and flavor: bitter, sweet, puckery, tepor.Gui Jing: return liver, the heart, kidney channel.Effect: removing toxic substances, eliminating carbuncle, preventing the attack (or recurrence) of malaria, loosening bowel to relieve constipation.Cure mainly: for carbuncle sore, scrofula, rubella pruritus, chronic malaria body is empty, dryness of the intestine constipation.
Call bright frightening (Dendrobium jenkinsii Wall ex Lindl．) together: base is former: the herb of the poly-Herba Dendrobii of orchid.Nature and flavor: sweet in the mouth, light, cool in nature.Effect: clearing heat and moistening lung, preventing phlegm from forming and stopping coughing, nourishing the lung to arrest cough, tonifying-Yin and nourishing-stomach.Cure mainly: cough due to lung-heat, pulmonary tuberculosis, asthma, dysentery, stomatitis, stomachache, children's's infantile malnutrition.
Spica Prunellae: base is former: be the dry fruit ear of labiate Spica Prunellae.Nature and flavor: pungent, bitter, cold.Gui Jing: return liver, gallbladder meridian.Effect: purging liver-fire, improving eyesight, mass dissipating and swelling eliminating.Cure mainly: for conjunctival congestion and swelling pain, order pearl nyctalgia, has a headache dizzy, scrofula, goiter, acute mastitis, nodules of the breast, distending pain of the breast.
Fructus Forsythiae: nature and flavor: hardship, is slightly cold.Gui Jing: return lung, the heart, small intestine meridian.Effect: heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, dispelling wind and heat pathogens.Cure mainly: for carbuncle, scrofula, acute mastitis, erysipelas, anemopyretic cold, epidemic febrile disease is from the beginning of, warm people battalion, high hot excessive thirst, coma is sent out speckle, the puckery pain of pyretic stranguria
Long stalk Herba lysimachiae capillipedis: base is former: be the herb of the long stalk of Primulaceae Lysimachia plant Lysimachia christinae Hance.Nature and flavor: sweet, flat.Effect: can control infantile convulsion.Hemoptysis of pulmonary tuberculosis, malaria.
Bombyx Batryticatus: base is former: the larva that belongs to animal bombyx mori for Bombycidae silkworm infects ossified Scorpio.Composition: Bombyx Batryticatus is containing protein, ammonium oxalate, and containing lysine, leucine, aminoacid in aspartic acid etc. 17,28 kinds of elements such as magnesium, calcium, zinc, and the composition such as abnormal active stimulin, ecdysone and a kind of pigment 3-hydroxyl cynruin.The property of medicine: pungent, salty, flat.Return liver, lung, stomach warp.Function cures mainly: expellings wind and relieving convulsion, and dissipating phlegm and resolving masses, resolving toxin and disinhibiting the throat.Cure mainly infantile convulsion and twitch, apoplexy facial hemiparalysis, migraine and general headache, laryngopharynx swelling and pain, scrofula, mumps, rubella, sore.Compatibility and incompatibility of drugs: blood deficiency is through the careful clothes of wind person.
The hard agent compounding method of lymphoid tuberculosis Huoxue San " provided by the invention is simple, crude drug wide material sources, and cost is lower.In addition, excellent results of the present invention also shows:
1, prescription of the present invention is with hard masses softening and resolving, and blood circulation and promoting silt is main effect;
2, this prescription not only has good effect to treatment lymphoid tuberculosis, has certain preventive effect simultaneously;
3, this Chinese drugs agentia is verified through clinical efficacy, reliable effect, and curative effect is fixed.
The specific embodiment
Below in conjunction with embodiment and test example, describe technical scheme of the present invention in detail, but protection domain is not limited to this.
embodiment 1the agent of lymphoid tuberculosis movable blood soft hard, is prepared from by following bulk drugs: Fructus Gleditsia veneer 5g, and Rhizoma Gastrodiae 4g, Radix Cirsii Japonici 3g, Stachys geobombycis C. Y. Wu 5g, Herba seu Radix Calanthes 6g, Herba Erigerontis Annui 6g, Radix Polygoni Multiflori 6g, calls the bright 18g of frightening together, Spica Prunellae 15g, Fructus Forsythiae 6g, long stalk Herba lysimachiae capillipedis 5g, Bombyx Batryticatus 3g.
The preparation method of above-mentioned lymphoid tuberculosis movable blood soft hard agent decoction is as follows:
(1) wheat bran is spread in heat pot, waits cigarette and rise, pour Bombyx Batryticatus into, fry to yellow, take out sieve and remove wheat bran, cool, pulverized 140 mesh sieves, must fry Bombyx Batryticatus powder, standby;
(2) Radix Cirsii Japonici is wrapped up to three layers with coarse toilet paper by medicine, put into water drenched, put in pot interior-heat sand and simmer to sallow, take out, cool, must simmer Radix Cirsii Japonici, standby;
(3) by Fructus Gleditsia veneer, Rhizoma Gastrodiae, Stachys geobombycis C. Y. Wu, Herba seu Radix Calanthes, Herba Erigerontis Annui, Radix Polygoni Multiflori, call together brightly frighten, Spica Prunellae, Fructus Forsythiae, long stalk Herba lysimachiae capillipedis put into marmite together with simmering Radix Cirsii Japonici with gained in step (2), soak 5 hours, the water surface exceeds 3 centimetres of medical materials, and then intense fire turns at a simmer after boiling, filter, decoct altogether twice, slow fire boiling for the first time 60 minutes, slow fire boiling for the second time 50 minutes, merge filtrate twice, heating is concentrated into the amount of Ligularia nelumbifolia(Bur. et Franch.) Hand.-Mazz., obtains medicinal liquid, standby;
(4) step (1) and (3) gained are fried to Bombyx Batryticatus powder and medicinal liquid mix homogeneously, obtain lymphoid tuberculosis movable blood soft hard agent decoction.
Model case: xxx, man, 35 years old.The year before, patient both sides cervical region swells and ache, and diabrosis after March is burst by not healing for a long time, follows the diabrosis of swelling and ache of right oxter, has formed ulcer and sinus tract, takes Western medicine, and effect is not remarkable.When medical, patient becomes thin, listless, with low grade fever, night sweat, light red tongue slight of stature, is diagnosed as cervical lymph node core.
Take the present embodiment gained lymphoid tuberculosis movable blood soft hard agent decoction, every day 3 times, each 40-50ml(is warm), within 8 days, be a course for the treatment of.Take after two courses for the treatment of, patient spirit takes a turn for the better, and low grade fever body temperature is normal, and night sweat is alleviated, and diabrosis and sinus tract start healing, and other malaise symptoms disappear, and continue to take two courses for the treatment of, and patient's diabrosis and sinus tract heal substantially, continues to strengthen a course for the treatment of of curative effect, recovery from illness.
embodiment 2the agent of lymphoid tuberculosis movable blood soft hard, is prepared from by following bulk drugs: Fructus Gleditsia veneer 12g, and Rhizoma Gastrodiae 7g, Radix Cirsii Japonici 9g, Stachys geobombycis C. Y. Wu 15g, Herba seu Radix Calanthes 10g, Herba Erigerontis Annui 9g, Radix Polygoni Multiflori 15g, calls the bright 32g of frightening together, Spica Prunellae 25g, Fructus Forsythiae 12g, long stalk Herba lysimachiae capillipedis 10g, Bombyx Batryticatus 6g.
The preparation method of above-mentioned lymphoid tuberculosis movable blood soft hard agent powder is as follows:
(1) wheat bran is spread in heat pot, waits cigarette and rise, pour Bombyx Batryticatus into, fry to yellow, take out sieve and remove wheat bran, cool, must fry Bombyx Batryticatus, standby;
(2) by Fructus Gleditsia veneer, Rhizoma Gastrodiae, Radix Cirsii Japonici, Stachys geobombycis C. Y. Wu, Herba seu Radix Calanthes, Herba Erigerontis Annui, Radix Polygoni Multiflori, call together brightly frighten, Spica Prunellae, Fructus Forsythiae, long stalk Herba lysimachiae capillipedis and fry Bombyx Batryticatus and make super cell grade 380 object micropowders, obtain powder.
Model case: xxx, man, 17 years old.Before three months, find in skin, to have under the ear of cervical region right side several of the swollen knots that Semen Glycines is large, press without pain, after become gradually large, appetite declines, lethargy.When medical, 38.8 ℃ of low grade fever, limbs fatigue, night sweat, pale tongue, white and thin fur, is diagnosed as the tuberculosis of cervical lymph nodes on inspection.
Take the present embodiment gained lymphoid tuberculosis movable blood soft hard agent powder, every day 3 times, each 5-7g, warm water is taken after mixing it with water, and within 8 days, is a course for the treatment of.Take after 9 days, low pyretolysis, spirit takes a turn for the better, and extremity strength strengthens.Continue to take a course for the treatment of, the swollen knot of patient diminishes, and size is Semen phaseoli radiati, continues to take a course for the treatment of, and patient's malaise symptoms disappears completely, and swollen knot also disappears completely, patient's recovery from illness.
embodiment 3the agent of lymphoid tuberculosis movable blood soft hard, is prepared from by following bulk drugs: Fructus Gleditsia veneer 7g, and Rhizoma Gastrodiae 5g, Radix Cirsii Japonici 5g, Stachys geobombycis C. Y. Wu 8g, Herba seu Radix Calanthes 7g, Herba Erigerontis Annui 7g, Radix Polygoni Multiflori 8g, calls the bright 23g of frightening together, Spica Prunellae 18g, Fructus Forsythiae 8g, long stalk Herba lysimachiae capillipedis 6g, Bombyx Batryticatus 4g.
The preparation method of above-mentioned lymphoid tuberculosis movable blood soft hard agent pill is as follows:
(1) wheat bran is spread in heat pot, waits cigarette and rise, pour Bombyx Batryticatus into, fry to yellow, take out sieve and remove wheat bran, cool, must fry Bombyx Batryticatus, standby;
(2) by Fructus Gleditsia veneer, Rhizoma Gastrodiae, Radix Cirsii Japonici, Stachys geobombycis C. Y. Wu, Herba seu Radix Calanthes, Herba Erigerontis Annui, Radix Polygoni Multiflori, call together brightly frighten, Spica Prunellae, Fructus Forsythiae, long stalk Herba lysimachiae capillipedis and fry Bombyx Batryticatus co-grinding and cross 120 mesh sieves, obtain medicated powder, standby;
(3) get it filled powder and Mel be take the ratio that mass ratio is 5:4 and is mixed and made into honeyed pill, and the size of ball is 2-3mm.
Model case: xxx, female, 47 years old.Abdominal part has 2 lymphoid tuberculosiss, and smooth surface is as pearl, and the movement pushing away, by being pressed with obvious pain, is diagnosed as lymphoid tuberculosis, and tuberculosis increases day by day.When medical, color of the leather is more dark red, and patient has low grade fever, Sleep hyperhidrosis, limbs fatigue.
Take gained lymphoid tuberculosis movable blood soft hard agent pill in the present embodiment, every day 3 times, each 3-5, warm water takes, and within 8 days, is a course for the treatment of.Take after 4 days, patient spirit takes a turn for the better, and feeling of fatigue alleviates, and Sleep hyperhidrosis is also alleviated, and continues to take two courses for the treatment of, and patient's malaise symptoms disappears substantially, and abdominal lymph node core diminishes as original 1/2nd, continues to take 5 days, and tuberculosis disappears completely, patient's recovery from illness.
embodiment 4the agent of lymphoid tuberculosis movable blood soft hard, is prepared from by following bulk drugs: Fructus Gleditsia veneer 10g, and Rhizoma Gastrodiae 6g, Radix Cirsii Japonici 7g, Stachys geobombycis C. Y. Wu 12g, Herba seu Radix Calanthes 9g, Herba Erigerontis Annui 8g, Radix Polygoni Multiflori 13g, calls the bright 27g of frightening together, Spica Prunellae 22g, Fructus Forsythiae 10g, long stalk Herba lysimachiae capillipedis 9g, Bombyx Batryticatus 5g.
The preparation method of above-mentioned lymphoid tuberculosis movable blood soft hard agent thick paste agent is as follows:
(1) wheat bran is spread in heat pot, waits cigarette and rise, pour Bombyx Batryticatus into, fry to yellow, take out sieve and remove wheat bran, cool, pulverized 140 mesh sieves, must fry Bombyx Batryticatus powder, standby;
(2) Radix Cirsii Japonici is wrapped up to three layers with coarse toilet paper by medicine, put into water drenched, put in pot interior-heat sand and simmer to sallow, take out, cool, must simmer Radix Cirsii Japonici, standby;
(3) by Fructus Gleditsia veneer, Rhizoma Gastrodiae, Stachys geobombycis C. Y. Wu, Herba seu Radix Calanthes, Herba Erigerontis Annui, Radix Polygoni Multiflori, call together brightly frighten, Spica Prunellae, Fructus Forsythiae, long stalk Herba lysimachiae capillipedis put into marmite together with simmering Radix Cirsii Japonici with gained in step (2), soak 5 hours, the water surface exceeds 3 centimetres of medical materials, and then intense fire turns at a simmer after boiling, and filters, decoct altogether twice, slow fire boiling for the first time 60 minutes, slow fire boiling for the second time 50 minutes, merges twice filtrate, to be concentrated into relative density be 1.20(60 ℃ in heating) clear paste, standby;
(4) step (1) and (3) gained are fried to Bombyx Batryticatus powder and clear paste mix homogeneously, obtain thick paste agent.
Model case: xxx, female, 55 years old.Main suit: have a Semen arachidis hypogaeae size enclosed mass without inducement discovery left side cervical region, quality is hard, and without adhesion, without tenderness, rear enlargement, to pigeon egg size, was once accepted antituberculosis drugs treat, and enclosed mass diminishes, but the decline of health tolerance, harmonization of the stomach liver occurs abnormal, suspends treatment.When medical, enclosed mass has Semen Glycines size, the hard and surrounding tissue part adhesion of quality, and tenderness sense is not obvious.
Take the agent of the present embodiment gained lymphoid tuberculosis movable blood soft hard agent thick paste, every day three times, each 15-20ml, 8 days is a course for the treatment of.Take after two courses for the treatment of, lump dwindles 70%, does not occur abnormal symptom, continues to take two courses for the treatment of, and lump disappears completely, patient's recovery from illness.
embodiment 5the agent of lymphoid tuberculosis movable blood soft hard, is prepared from by following bulk drugs: Fructus Gleditsia veneer 8.5g, Rhizoma Gastrodiae 5.5g, Radix Cirsii Japonici 6g, Stachys geobombycis C. Y. Wu 10g, Herba seu Radix Calanthes 8g, Herba Erigerontis Annui 7.5g, Radix Polygoni Multiflori 10.5g, calls the bright 25g of frightening together, Spica Prunellae 20g, Fructus Forsythiae 9g, long stalk Herba lysimachiae capillipedis 7.5g, Bombyx Batryticatus 4.5g.
The preparation method of above-mentioned lymphoid tuberculosis movable blood soft hard agent powder is as follows:
(1) wheat bran is spread in heat pot, waits cigarette and rise, pour Bombyx Batryticatus into, fry to yellow, take out sieve and remove wheat bran, cool, must fry Bombyx Batryticatus, standby;
(2) by Fructus Gleditsia veneer, Rhizoma Gastrodiae, Radix Cirsii Japonici, Stachys geobombycis C. Y. Wu, Herba seu Radix Calanthes, Herba Erigerontis Annui, Radix Polygoni Multiflori, call together brightly frighten, Spica Prunellae, Fructus Forsythiae, long stalk Herba lysimachiae capillipedis and fry Bombyx Batryticatus and make super cell grade 380 object micropowders, obtain powder.
test example 1the clinical practice of embodiment 5 gained lymphoid tuberculosis movable blood soft hard agent: in June, 2011-2013 year February, screen 376 routine patients in 3 hospitals, MethodsThe cases enrolled is the lymphoid tuberculosis patient who makes a definite diagnosis.Test first 7 days, this crowd is carried out to Continuous Observation, record symptom and variation, be divided at random two groups, experimental group and matched group, two groups of comparing differences are without significance.
Experimental group: 216 patients, male's 84 examples, women's 132 examples, the oldest 64 years old, minimum 12 years old, 34.2 years old mean age.Ill initial stages 143 example wherein, mid-terms 50 example, late periods 23 example.Take embodiment 5 products obtained therefroms, using method is: taken three times a day, each 5-7g(adjusts to some extent depending on concrete condition), warm water takes, and within 8 days, is a course for the treatment of.
Matched group: 160 patients, male's 80 examples, women's 80 examples, the oldest 63 years old, minimum 12 years old, 34.3 years old mean age.Ill initial stages 103 example wherein, mid-terms 47 example, late periods 10 example.Use treatment scrofulous conventional medicine (as isoniazid, ethambutol, rifampicin etc.).
Curative effect judging standard: cure: wound healing, incrustation, lymphoid tuberculosis lump disappears completely; Effective: lymphoid tuberculosis lump diminishes, and the open sore part starts the raw meat that heals, low grade fever disappears; Effective: low grade fever alleviates, the routed liquid of outflow also starts to reduce, and lymphoid tuberculosis lump diminishes gradually; Invalid: with treatment before compare, symptom is without improvement.
Therapeutic outcome is as shown in table 1.
Table 1:
As known from Table 1, use embodiment 5 products obtained therefroms after 25 days, the patient of clinical cure, the state of an illness are clearly better and treat effective patient and always have 212 examples, account for 98.2%, cure invalid 4 examples that only have, account for 1.8%, the total effective rate that is experimental group is 98.2%, the cure rate of matched group, obvious effective rate and effective percentage are respectively 63.8%, 10.6% and 12.5%, and total effective rate is 86.9%, and the clinical therapeutic efficacy of visible experimental group is good compared with matched group.
Fructus Gleditsia veneer and Fructus Forsythiae heat-clearing and toxic substances removing in the present invention's formula, dispersing swelling and dissipating binds; Radix Cirsii Japonici and Herba Erigerontis Annui cooling blood for hemostasis; Herba seu Radix Calanthes and call the bright heat-clearing and toxic substances removing that frightens, promoting blood circulation and stopping pain, moistening the lung and resolving phlegm together; Rhizoma Gastrodiae endogenous wind stopping relieving convulsion, dispelling wind and removing obstruction in the collateral; Stachys geobombycis C. Y. Wu nourishing YIN and supplementing blood, clearing heat and relieving fidgetness; Spica Prunellae purging liver-fire, dispersing swelling and dissipating binds, inducing diuresis for treating stranguria syndrome; Bombyx Batryticatus dissipating phlegm and resolving masses, resolving toxin and disinhibiting the throat.Multiple medical material shares, collaborative performance drug effect, and to reach heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, the effect of hard masses softening and resolving, therefore, has significant curative effect for lymphoid tuberculosis.
It should be pointed out that the specific embodiment is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clearly disclosed or according to undoubted the obtaining of the written description of file, all should think the claimed scope of this patent.
Claims (10)
1. the agent of lymphoid tuberculosis movable blood soft hard, is characterized in that, mainly by following bulk drugs, is prepared from, be weight portion: Fructus Gleditsia veneer 5-12, Rhizoma Gastrodiae 4-7, Radix Cirsii Japonici 3-9, Stachys geobombycis C. Y. Wu 5-15, Herba seu Radix Calanthes 6-10, Herba Erigerontis Annui 6-9, Radix Polygoni Multiflori 6-15, call the bright 18-32 of frightening together, Spica Prunellae 15-25, Fructus Forsythiae 6-12, long stalk Herba lysimachiae capillipedis 5-10, Bombyx Batryticatus 3-6.
2. movable blood soft hard agent as claimed in claim 1, is characterized in that, mainly by following bulk drugs, is prepared from, be weight portion: Fructus Gleditsia veneer 7-10, Rhizoma Gastrodiae 5-6, Radix Cirsii Japonici 5-7, Stachys geobombycis C. Y. Wu 8-12, Herba seu Radix Calanthes 7-9, Herba Erigerontis Annui 7-8, Radix Polygoni Multiflori 8-13, call the bright 23-27 of frightening together, Spica Prunellae 18-22, Fructus Forsythiae 8-10, long stalk Herba lysimachiae capillipedis 6-9, Bombyx Batryticatus 4-5.
3. movable blood soft hard agent as claimed in claim 1, is characterized in that, mainly by following bulk drugs, is prepared from, be weight portion: Fructus Gleditsia veneer 8.5, Rhizoma Gastrodiae 5.5, Radix Cirsii Japonici 6, Stachys geobombycis C. Y. Wu 10, Herba seu Radix Calanthes 8, Herba Erigerontis Annui 7.5, Radix Polygoni Multiflori 10.5, call together and brightly frighten 25, Spica Prunellae 20, Fructus Forsythiae 9, long stalk Herba lysimachiae capillipedis 7.5, Bombyx Batryticatus 4.5.
4. the movable blood soft hard agent as described in as arbitrary in claim 1-3, is characterized in that, this medicament be can be made into pharmaceutically acceptable decoction, powder, pill and thick paste agent.
5. movable blood soft hard agent as claimed in claim 4, is characterized in that, the preparation method of described decoction is as follows:
(1) wheat bran is spread in heat pot, waits cigarette and rise, pour Bombyx Batryticatus into, fry to yellow, take out sieve and remove wheat bran, cool, pulverized 100 order-180 orders (preferably 140 orders) sieve, must fry Bombyx Batryticatus powder, standby;
(2) Radix Cirsii Japonici is wrapped up to three layers with coarse toilet paper by medicine, put into water drenched, put in pot interior-heat sand and simmer to sallow, take out, cool, must simmer Radix Cirsii Japonici, standby;
(3) by Fructus Gleditsia veneer, Rhizoma Gastrodiae, Stachys geobombycis C. Y. Wu, Herba seu Radix Calanthes, Herba Erigerontis Annui, Radix Polygoni Multiflori, call together brightly frighten, Spica Prunellae, Fructus Forsythiae, long stalk Herba lysimachiae capillipedis put into marmite together with simmering Radix Cirsii Japonici with gained in step (2), soak 4-6 hour (preferably 5 hours), the water surface exceeds 3 centimetres of medical materials, then intense fire turns at a simmer after boiling, filter, decoct altogether twice, slow fire boiling 40-80 minute for the first time (preferably 60 minutes), slow fire boiling 40-60 minute for the second time (preferably 50 minutes), merge filtrate twice, heating is concentrated into the amount of Ligularia nelumbifolia(Bur. et Franch.) Hand.-Mazz., obtains medicinal liquid, standby;
(4), by step (1) and (3) gained Bombyx Batryticatus (parched) powder and medicinal liquid mix homogeneously, obtain lymphoid tuberculosis movable blood soft hard agent decoction.
6. movable blood soft hard agent as claimed in claim 4, is characterized in that, the preparation method of described powder is:
(1) wheat bran is spread in heat pot, waits cigarette and rise, pour Bombyx Batryticatus into, fry to yellow, take out sieve and remove wheat bran, cool, must fry Bombyx Batryticatus, standby;
(2) by Fructus Gleditsia veneer, Rhizoma Gastrodiae, Radix Cirsii Japonici, Stachys geobombycis C. Y. Wu, Herba seu Radix Calanthes, Herba Erigerontis Annui, Radix Polygoni Multiflori, call together brightly frighten, Spica Prunellae, Fructus Forsythiae, long stalk Herba lysimachiae capillipedis and fry Bombyx Batryticatus and make super cell grade 380 object micropowders, obtain powder.
7. movable blood soft hard agent as claimed in claim 4, is characterized in that, the preparation method of described pill is:
(1) wheat bran is spread in heat pot, waits cigarette and rise, pour Bombyx Batryticatus into, fry to yellow, take out sieve and remove wheat bran, cool, must fry Bombyx Batryticatus, standby;
(2) by Fructus Gleditsia veneer, Rhizoma Gastrodiae, Radix Cirsii Japonici, Stachys geobombycis C. Y. Wu, Herba seu Radix Calanthes, Herba Erigerontis Annui, Radix Polygoni Multiflori, call together brightly frighten, Spica Prunellae, Fructus Forsythiae, long stalk Herba lysimachiae capillipedis and fry Bombyx Batryticatus co-grinding and cross 120 mesh sieves, obtain medicated powder, standby;
(3) get it filled powder and Mel is mixed and made into honeyed pill, and the size of ball is 2-3mm.
8. movable blood soft hard agent as claimed in claim 7, is characterized in that, the mass ratio of step (3) Chinese medicine powder and Mel is 5:4.
9. movable blood soft hard agent as claimed in claim 4, is characterized in that, the preparation method of described thick paste agent is:
(1) wheat bran is spread in heat pot, waits cigarette and rise, pour Bombyx Batryticatus into, fry to yellow, take out sieve and remove wheat bran, cool, pulverized 100 order-180 orders (preferably 140 orders) sieve, obtain Bombyx Batryticatus (parched) powder, standby;
(2) Radix Cirsii Japonici more than three layers, is put into water drenched with coarse toilet paper by medicine parcel, put in pot interior-heat sand and simmer to sallow, take out, cool, must simmer Radix Cirsii Japonici, standby;
(3) by Fructus Gleditsia veneer, Rhizoma Gastrodiae, Stachys geobombycis C. Y. Wu, Herba seu Radix Calanthes, Herba Erigerontis Annui, Radix Polygoni Multiflori, call bright frightening together, Spica Prunellae, Fructus Forsythiae, long stalk Herba lysimachiae capillipedis is put into marmite together with simmering Radix Cirsii Japonici with gained in step (2), soak 4-6 hour (preferably 5 hours), the water surface exceeds 3 centimetres of medical materials, then intense fire turns at a simmer after boiling, filter, decoct altogether twice, slow fire boiling 40-80 minute for the first time (preferably 60 minutes), slow fire boiling 40-60 minute for the second time (preferably 50 minutes), merge filtrate twice, it is 1.18-1.22(preferably 1.20 that heating is concentrated into relative density) clear paste of (60 ℃), standby,
(4) step (1) and (3) gained are fried to Bombyx Batryticatus powder and clear paste mix homogeneously, obtain thick paste agent.
10. the application of the movable blood soft hard agent as described in as arbitrary in claim 1-3 when the medicine of preparation treatment lymphoid tuberculosis and lymphadenectasis.
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