CN107343948A - It is a kind of effectively to treat pill medicine of hepatitis B and preparation method thereof - Google Patents

It is a kind of effectively to treat pill medicine of hepatitis B and preparation method thereof Download PDF

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CN107343948A
CN107343948A CN201710662080.0A CN201710662080A CN107343948A CN 107343948 A CN107343948 A CN 107343948A CN 201710662080 A CN201710662080 A CN 201710662080A CN 107343948 A CN107343948 A CN 107343948A
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root
medicine
hepatitis
chinese
madder
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罗娟
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Chengdu Feilong Water Treatment Technology Institute
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Chengdu Feilong Water Treatment Technology Institute
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9066Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/233Bupleurum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489Sophora, e.g. necklacepod or mamani
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537Salvia (sage)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/57Magnoliaceae (Magnolia family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/65Paeoniaceae (Peony family), e.g. Chinese peony
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/185Magnoliopsida (dicotyledons)
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
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    • A61K9/2068Compounds of unknown constitution, e.g. material from plants or animals

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Abstract

The invention belongs to field of traditional Chinese, it is therefore an objective to which a kind of pill medicine that can effectively treat hepatitis B provided according to the understanding mechanism of Chinese traditional treatment hepatitis B, each component and its mass parts ratio of the medicine are as follows:90~160g of hypericum japonicum, 30~100g of ginseng, 250~550g of Whitebackleaf Mallotus Root, 80~160g of the red sage root, 30~120g of Morinda officinalis, 150~280g of the Radix Astragali, 30~120g of root tuber of aromatic turmeric, 15~70g of the fruit of Chinese magnoliavine, 100~250g of the root of herbaceous peony, 30~70g of subprostrate sophora, 60~100g of madder, 30~120g of radix bupleuri, 90~160g of giant knotweed;Medicine provided by the invention is a good Chinese prescription.

Description

It is a kind of effectively to treat pill medicine of hepatitis B and preparation method thereof
Technical field
The invention belongs to field of traditional Chinese, and in particular to a kind of pill medicine that can effectively treat hepatitis B, especially It is the field of the pill medicine used for hepatitis B patient and preparation method thereof.
Background technology
Hepatitis B, hepatitis B abbreviation hepatitis B is clinical common transmittable disease, and traditional Chinese medicine thinks empty, heat(Poison), the wet, stasis of blood, The strongly fragrant basic pathology for hepatitis B, so as to cause hepatitis B to have, infectiousness is strong, the incidence of disease is high, the course of disease is long, easy recurrence, liver The features such as functional lesion, hepatitis B have turned into worldwide distribution, popular communicable disease, while are also to seriously endanger the people A kind of common disease, the frequently-occurring disease of health, about 26% patient finally develop into hepatic sclerosis and liver cancer.
So, just how to find a kind of Chinese medicine composition that can effectively treat hepatitis B, be those skilled in the art urgently The problem of to be resolved.
The content of the invention
With the continuous development of China's traditional Chinese medicine, in treatment hepatitis B, people gradually appreciate middle treatment The advantages for the treatment of hepatitis B, and good effect, the advantage such as quick, toxic side effect is small over the course for the treatment of, control for existing doctor trained in Western medicine The present situation of hepatitis B is treated, the purpose of the present invention is to be to provide a kind of pill medicine that can effectively treat hepatitis B, with solution The problem of certainly hepatitis B patient is got well early.The medicine is using common Chinese medicine as raw material, by selecting rational medicine Thing and mass parts ratio, can effectively treat above-mentioned hepatitis B.
To reach the purpose of foregoing invention, the technical solution adopted in the present invention is:Offer one kind can effectively treat B-mode Pill medicine of hepatitis and preparation method thereof, it is characterised in that each component and its mass parts of the medicine are than as follows:
90~160g of hypericum japonicum, 30~100g of ginseng, 250~550g of Whitebackleaf Mallotus Root, 80~160g of the red sage root, 30~120g of Morinda officinalis, 150~280g of the Radix Astragali, 30~120g of root tuber of aromatic turmeric, 15~70g of the fruit of Chinese magnoliavine, 100~250g of the root of herbaceous peony, 30~70g of subprostrate sophora, madder 60~ 100g, 30~120g of radix bupleuri, 90~160g of giant knotweed, appropriate starch.
It is a kind of effectively to treat pill medicine of hepatitis B and preparation method thereof, it is characterised in that the medicine it is each Individual component and its mass parts are than as follows:
100~140g of hypericum japonicum, 36~90g of ginseng, 280~480g of Whitebackleaf Mallotus Root, 90~140g of the red sage root, 38~105g of Morinda officinalis, 180~250g of the Radix Astragali, 36~105g of root tuber of aromatic turmeric, 20~60g of the fruit of Chinese magnoliavine, 115~220g of the root of herbaceous peony, 35~60g of subprostrate sophora, madder 70~ 90g, 36~105g of radix bupleuri, 100~140g of giant knotweed, appropriate starch.
It is a kind of effectively to treat pill medicine of hepatitis B and preparation method thereof, it is characterised in that " the optimal side The each component and its mass parts of the medicine of case " are than as follows:
Hypericum japonicum 120g, ginseng 80g, Whitebackleaf Mallotus Root 420g, red sage root 120g, Morinda officinalis 95g, Radix Astragali 220g, root tuber of aromatic turmeric 95g, the fruit of Chinese magnoliavine 50g, root of herbaceous peony 200g, subprostrate sophora 50g, madder 80g, radix bupleuri 95g, giant knotweed 120g, appropriate starch.
It is a kind of effectively to treat pill medicine of hepatitis B and preparation method thereof, it is characterised in that methods described includes Following steps are prepared:
A, in addition to starch, after above-mentioned raw materials Chinese medicine is picked impurity, dust and dried, it is ground into superfine end according to mass parts ratio and treats With;
B, the method for preparing Chinese kmedicine bolus agent according to tradition, after ground superfine myrrh thing and starch sieving, it is put into medicine device Middle mixing is mixed, is then prepared into water-bindered pill agent(The granularity of its water-bindered pill is:3.9mm~4.0mm), then dry, sterilize, packing is close Envelope.
It is a kind of effectively to treat pill medicine of hepatitis B and preparation method thereof, it is characterised in that the instructions of taking For:By the water pill medicine prepared twice a day to take, once a dose sooner or later, dosage 7g/ times, warm water delivery service.30 It is a course for the treatment of, and 2~5 courses for the treatment of of taking medicine, symptom gradually mitigates or fully recovered.
Each raw material Chinese medicine in prescription of the present invention has detailed note in Chinese Pharmacopoeia, Chinese dictionary and China's book on Chinese herbal medicine Carry.The present invention is raw material from most common of which Chinese medicine, gives full play to the pharmacological effect of each component:
Hypericum japonicum, nature and flavor:It is sweet, bitter, cool, there is the effect of clearing heat and promoting diuresis, removing toxic substances, eliminating stasis to subdue swelling, for treating jaundice with damp-heat pathogen, letting out Rush down, dysentery, acute appendicitis, carbuncle furuncle poison, acute tonsillitis, aphtha, red eye, swell pain, venomous snake bite, traumatic injury;
Ginseng, nature and flavor:It is sweet, slight bitter, flat, have reinforce vital energy, veins takes off admittedly, the effect of reinforcing the spleen to benefit the lung, promote the production of body fluid, calming the nerves, be used for Treat it is physically weak to be taken off, cold weak pulse of limb, spleen eating less, the deficiency syndrome of the lung are breathed with cough, injury thirst, Heat Diabetes, prolonged illness void are thin, insomnia of palpitating with fear, Impotence Gong Leng, heart failure, cardiogenic shock;
Whitebackleaf Mallotus Root, nature and flavor:Slight bitter, puckery, flat, root:It is the effect of with soft liver promoting blood circulation, invigorating the spleen for eliminating dampness, astringing and avoiding visceroptosis, slow for treating Property hepatitis, hepatosplenomegaly, the prolapse of uterus, prolapse of the anus, leukorrhea, cyesedema;Leaf:The effect of with anti-inflammation hemostasia, middle ear are controlled in external application Inflammation, furuncle, traumatic injury, traumatism and bleeding;
The red sage root, nature and flavor:Bitter, cold nature, there is the effect of promoting blood circulation, menstruction regulating and pain relieving, nourishing blood and tranquilization, cool blood to disappear carbuncle, be used for Treat menoxenia, dysmenorrhoea, Amenorrhea, postpartum stasis of blood, trusted subordinate's pain, a lump in the abdomen causing distension and pain, the swelling and pain of hot numbness, traumatic injury, Heat enters ying blood, dysphoria, vexed insomnia, ulcerative carbuncle pyogenic infections;
Morinda officinalis, nature and flavor:Sweet, pungent, tepor, there is the effect of kidney-replenishing, strengthening the bones and muscles, wind-damp dispelling, for treating impotence and seminal emission, palace Cold infertile, irregular menstruation, few abdomen crymodynia, arthralgia pain due to rheumatism, muscles and bones impotence;
The Radix Astragali, nature and flavor:Sweet, tepor, there is the effect of solid table of polishing, torr sore myogenic, for treat physically weak spontaneous perspiration, chronic diarrhea, prolapse of the anus, The prolapse of uterus, chronic nephritis, physically weak edema, chronic ulcer, the long disunion of the open sore part;
Root tuber of aromatic turmeric, nature and flavor:It is acrid flavour, hardship, cold in nature, there is the effect of promoting blood circulation stops energy, promoting qi circulation and removing obstruction in the collateral, the cool blood that clears away heart-fire, soothing liver-gallbladder, be used for Treat all pains of chest and abdomen side of body rib, dysmenorrhes, Amenorrhea, Disorder lumps in the abdomen caking, pyreticosis coma, demented, frightened epilepsy, haematemesis, be defeated in battle standby, blood strangury, sand The diseases such as leaching, jaundice;
The fruit of Chinese magnoliavine, nature and flavor:It is sour, sweet, warm, there is the effect of restraining astringent or styptic treatment for spontaneous sweating, nourishing generate fluid, kidney calming, for treating void of coughing long Asthma, emission, enuresis frequent micturition, endless diarrhea, spontaneous perspiration, night sweat, injury thirst, feeble pulse of losing heart, Heat Diabetes, palpitation and insomnia;
The root of herbaceous peony, nature and flavor:Bitter, acid, it is slightly cold, blood-nourishing and battalion, relieving spasm to stop pain, holds back the effect of high and level tone liver, for treats irregular menstruation, warp The diseases such as row stomachache, uterine bleeding, spontaneous perspiration, night sweat, side of body rib epigastric pain, four limbs contraction pain, headache, dizziness;
Subprostrate sophora, nature and flavor:It is bitter, cold, it is poisonous, there is the effect of clearing heat and detoxicating, detumescence relieving sore-throat, pented up for treating fiery poison, throat Swelling and pain, gingivitis;
Madder, nature and flavor:It is bitter, cold, there is cool blood, hemostasis, dissolving stasis, the effect of stimulating the menstrual flow, for treating haematemesis, bleeding from five sense organs or subcutaneous tissue, uterine bleeding, wound Bleeding, Amenorrhea stasis blocking, joint pain, tumbling and swelling;
Radix bupleuri, nature and flavor:Bitter, pungent, cold nature, there is inducing diaphoresis to bring down a fever, soothing liver-qi stagnation, rise the effect of lifting yang-energy, it is outer for treating Feel heating, fevers and chills alternate, malaria, liver-depressed hypochondrium pain mammary swelling, have a headache a dizzy, irregular menstruation, the prolapse of the anus of collapse from qi deficiency, the prolapse of uterus, The diseases such as gastroptosis;
Giant knotweed, nature and flavor:Slight bitter, be slightly cold, have expelling wind and removing dampness, scattered stasis pain, it is relieving cough and reducing sputum the effect of, for treating joint numbness Bitterly, jaundice with damp-heat pathogen, Amenorrhea, abdominal mass, scald, injury from falling down, carbuncle sore tumefacting virus, coughing with a lot of sputum.
Medicine of the present invention is the principle based on Chinese traditional treatment hepatitis B, from the pathomechanism and pharmacology according to hepatitis B Effect is thought:With regard to hepatitis B, each raw material herbal medicine efficacy in medicine provided by the present invention is played altogether, is had very well to above-mentioned disease Therapeutic effect.
Embodiment
A kind of Chinese medicine preparation that the present invention proposes aiming at the treatment of above-mentioned hepatitis B, prepared using the formula Medicine effect is good, quick, is a Chinese prescription treated both principal and secondary aspect of disease, is particularly suitable for Clinical practice.With reference to the present invention's Embodiment is described in further detail:
Embodiment 1:
A kind of pill medicine that can effectively treat hepatitis B, it is characterised in that each component and its mass parts of the medicine Than as follows:
Hypericum japonicum 120g, ginseng 80g, Whitebackleaf Mallotus Root 420g, red sage root 120g, Morinda officinalis 95g, Radix Astragali 220g, root tuber of aromatic turmeric 95g, the fruit of Chinese magnoliavine 50g, root of herbaceous peony 200g, subprostrate sophora 50g, madder 80g, radix bupleuri 95g, giant knotweed 120g, appropriate starch.
Embodiment 2:
A kind of pill medicine that can effectively treat hepatitis B, it is characterised in that each component and its mass parts of the medicine Than as follows:
Hypericum japonicum 140g, ginseng 90g, Whitebackleaf Mallotus Root 480g, red sage root 140g, Morinda officinalis 105g, Radix Astragali 250g, root tuber of aromatic turmeric 105g, the five tastes Sub- 60g, root of herbaceous peony 220g, subprostrate sophora 60g, madder 90g, radix bupleuri 105g, giant knotweed 140g, appropriate starch.
Embodiment 3:
A kind of pill medicine that can effectively treat hepatitis B, it is characterised in that each component and its mass parts of the medicine Than as follows:
Hypericum japonicum 160g, ginseng 100g, Whitebackleaf Mallotus Root 550g, red sage root 160g, Morinda officinalis 120g, Radix Astragali 280g, root tuber of aromatic turmeric 120g, the five tastes Sub- 70g, root of herbaceous peony 250g, subprostrate sophora 70g, madder 100g, radix bupleuri 120g, giant knotweed 160g, appropriate starch.
Model case
Through clinical conditions hepatitis B patient totally 1280, the age is 750 of more than 27 years old, and only 480 are 27 years old Below.Symptom gradually mitigates or fully recovered in 1280 patients 930, effective 222, invalid 128.Total effective rate reaches 90%。

Claims (3)

1. a kind of pill medicine that can effectively treat hepatitis B, it is characterised in that each component and its quality of the medicine Part is than as follows:
90~160g of hypericum japonicum, 30~100g of ginseng, 250~550g of Whitebackleaf Mallotus Root, 80~160g of the red sage root, 30~120g of Morinda officinalis, 150~280g of the Radix Astragali, 30~120g of root tuber of aromatic turmeric, 15~70g of the fruit of Chinese magnoliavine, 100~250g of the root of herbaceous peony, 30~70g of subprostrate sophora, madder 60~ 100g, 30~120g of radix bupleuri, 90~160g of giant knotweed, appropriate starch.
2. the pill medicine according to claim 1 that can effectively treat hepatitis B, it is characterised in that the medicine it is each Individual component and its mass parts are than as follows:
100~140g of hypericum japonicum, 36~90g of ginseng, 280~480g of Whitebackleaf Mallotus Root, 90~140g of the red sage root, 38~105g of Morinda officinalis, 180~250g of the Radix Astragali, 36~105g of root tuber of aromatic turmeric, 20~60g of the fruit of Chinese magnoliavine, 115~220g of the root of herbaceous peony, 35~60g of subprostrate sophora, madder 70~ 90g, 36~105g of radix bupleuri, 100~140g of giant knotweed, appropriate starch.
3. the pill medicine that can effectively treat hepatitis B according to claim 1 to 2, it is characterised in that the medicine Each component and its mass parts than as follows:
Hypericum japonicum 120g, ginseng 80g, Whitebackleaf Mallotus Root 420g, red sage root 120g, Morinda officinalis 95g, Radix Astragali 220g, root tuber of aromatic turmeric 95g, the fruit of Chinese magnoliavine 50g, root of herbaceous peony 200g, subprostrate sophora 50g, madder 80g, radix bupleuri 95g, giant knotweed 120g, appropriate starch.
CN201710662080.0A 2017-08-04 2017-08-04 It is a kind of effectively to treat pill medicine of hepatitis B and preparation method thereof Withdrawn CN107343948A (en)

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CN1100642A (en) * 1993-09-22 1995-03-29 李彤 Chinese medicine preparation for treating viral hepatitis B
CN1136939A (en) * 1995-10-10 1996-12-04 卢颖 Chinese drugs for curing hepatitis B
CN1167637A (en) * 1997-04-15 1997-12-17 胡安黎 Medicine for removing hepatitis B virus and preparing method thereof
CN1176123A (en) * 1996-02-15 1998-03-18 邵阳县中医院 Medicine for chronic hepatitis B and its preparation
CN1207314A (en) * 1998-04-28 1999-02-10 叶坦 Chinese medicine for treating hepatitis B
CN1211439A (en) * 1997-09-13 1999-03-24 郭子清 Chinese herbal medicine preparation for treating B hepatitis
CN1244405A (en) * 1998-08-11 2000-02-16 张贤贵 Medicine for hepatitis B and its preparation
CN1456227A (en) * 2003-02-12 2003-11-19 朱培田 Medicine for curing hepatitis B
CN103977306A (en) * 2014-05-28 2014-08-13 赵红侠 Medicament for treating hepatitis B and preparation method thereof
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