CN1253733A - Formula of liver-protecting milk powder and its production process - Google Patents
Formula of liver-protecting milk powder and its production process Download PDFInfo
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- CN1253733A CN1253733A CN 99113129 CN99113129A CN1253733A CN 1253733 A CN1253733 A CN 1253733A CN 99113129 CN99113129 CN 99113129 CN 99113129 A CN99113129 A CN 99113129A CN 1253733 A CN1253733 A CN 1253733A
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Abstract
The production process of liver-protecting milk powder is characterized by using common milk powder as carrier, adding the extracts of Chinese medicinal materials of ligustrum fruit, licorice, astragalus root and vitamin C, B1, B2 and cane sugar and adopting the conventional production process of milk powder so as to obtain the invented product. Said dietary health-care milk powder not only can intensify its nutrient function for liver, but also can promote the restoration and regeneration of liver cell, reduce transaminase, and is applicable to various patients with hepatitis, alcoholic hepatitis and fatty liver.
Description
The present invention relates to a kind of Dietotherapy health milk powder.
The incidence of disease of China's hepatopathy is higher, almost account for 20% of total population, discovery along with third liver, viral hepatitis type E, alcoholic liver, fatty liver crowd's increase hepatopathy is the trend of rising, though there is the medicine of a lot of treatment hepatopathys in China, effect is all bad, can not effect a radical cure, and protect liver nutraceutical also good without comparison kind at present, addressing this problem becomes urgent need.
Task of the present invention is: overcome the deficiencies in the prior art, design a kind of liver-protecting milk powder and manufacturing process thereof that liver is had health care.
Task of the present invention realizes as follows:
Its prescription is: get fresh milk (concentration is 11.2%) 2000 grams
Sucrose 60 grams
Isomalto-oligosaccharide 48 grams
Skimmed milk power 40 grams
Desalted whey powder 20 grams
Vitamin C 0.28 gram
Cobastab
10.008 gram
Cobastab
20.008 gram
The Radix Astragali 25 grams
Radix Glycyrrhizae 7.5 grams
The fruit of glossy privet 7.5 grams
Its production technology is: a, the Chinese medicine fruit of glossy privet, Radix Glycyrrhizae, the Radix Astragali are extracted secondary in 1: 1: 4 ratio with 95% alcohol reflux, each 2 hours, then with its filtration, merge extract, filtrate is used the activated carbon decolorizing secondary, destainer is reclaimed ethanol, and to make it to become concentration be 1.20, and temperature is 80 ℃ a liquid extract, and the liquid extract spray-drying is just become dry powder additive; (4 ℃) are stored in b, fresh milk examination → metering → purification → cooling, with vitamin V c, B
1, B
2(three's ratio is 35: 1: 1) all adds the standardization of preparing burden in the fresh milk with the fruit of glossy privet, the Radix Astragali, licorice in sucrose, isomalto-oligosaccharide, skimmed milk power, the desalted whey powder of 1: 13.5 ratio and dissolving respectively; C, preheating (50-60 ℃); D, homogeneous (20-25MPa); E, cooling are stored; F, sterilization, concentrated (sterilization temperature 86-92 ℃ is incubated 24 seconds, concentration 43-48%); G, enter dense milk cold wall tank; H, spray-drying, 160 ℃ of air intakes, 80 ℃ of air drafts; I, vibrated fluidized bed cooling, sieve powder (<15 ℃); Z, conveying, metering, vacuum nitrogen automatic gauge packing; Y, product inspection, the certified products warehouse-in.
The present invention can strengthen the trophism to liver like this owing to strengthened protein and the ratio of sugar in prescription; The maximum that adopts RDA to recommend has strengthened Vc, V
B2, V
B1Ratio, to strengthen nutrition and protective effect, suitably reduced fatty ratio with the formation that alleviates fatty liver and fat burden to liver to liver; The present invention is in conjunction with modern Chinese herbal medicine composition chemistry and pharmacological achievement in research, in prescription, add the Chinese medicine that liver protection effect is arranged, utilize the extractive technique of modern Chinese herbal medicine active ingredient will have the fruit of glossy privet, the Radix Astragali of liver protection effect, the active ingredient of Radix Glycyrrhizae adds in the milk powder, both guaranteed that the liver function of protecting in the milk powder imitated composition, guaranteed again that milk powder had good color and luster and grows smell;
Because the fruit of glossy privet in the prescription of the present invention contains a large amount of oleanolic acids, this composition has the stronger liver effect of reducing enzyme levels that protects, measure alpha-fetoprotein by the content of the triglycerides of glutamic-pyruvic transaminase, hepatic tissue in the determination experiment rat blood serum and with the reverse blood clotting method, liver tissues of rats is done histological observation and histochemistry's observation, find CCL
4Cause that GPT obviously descends in the poisoning rat serum, triglycerides is accumulated minimizing in the liver, and histology and histochemistry show degeneration of liver cells, downright bad obviously alleviating, and glycogen accumulates increase, and the RNA particle recovers in the endochylema, shows that oleanolic acid can be to CCL
4The acute and chronic liver injury that causes has significant protective effect, can prevent the generation of cirrhosis, and is by suppressing or alleviating degeneration of liver cells with downright bad; Promote liver cell regeneration, quicken the reparation of slough; Suppress the reaction of collagen hyperplasia and nonspecific inflammation,, bring into play its hepatoprotective effect so that cirrhosis is difficult to form; Because the Radix Glycyrrhizae in the prescription contains glycyrrhizic acid and enoxolone, this composition has stronger antivirus action and strengthens immunization, for hepatic injury the better protect effect is arranged also.With liquorice beverage decocting liquid treatment hepatitis, it is normal that average icterus index was recovered in 12.9 days in clinical research, and the test of urine courage transferred feminine gender at 9.9 days, and hepatomegaly was significantly dwindled in about 9.2 days, and hepatodynia disappeared in 7.8 days.
Because the Radix Astragali in the prescription of the present invention contains active ingredient such as Astragaloside IV, astragalus polyose and multiple flavones, amino acid etc., experimental study shows that Astragaloside IV has choleretic effect to experimental rat, and its rat small intestine in vitro, bladder are separated the spasm effect, to CCL
4In the mouse liver injury experiment that paracetamol and absolute ethyl alcohol cause, astragalus polyose has stronger protective effect.Another experiment shows, Astragalus Root P.E can make the immune function of mice of immunologic hypofunction recover normal, and LSI obviously increases, and decline is recovered to the old rats immunologic function, strengthen resistance against diseases, thereby can improve the resistance of liver damage.Suppress to experiment showed, that the Radix Astragali has certain inhibitory action through hepatitis a and b virus, HBsAg is turned out cloudy, have the hepatic tissue of alleviating sex change, necrosis and inflammatory cell infiltration simultaneously and alleviate the formation of liver fiber, promote the effect that damaging cells is repaired.
Fig. 1 is for adding the extraction process flow chart of Chinese herbal medicine in the present invention's prescription;
Fig. 2 is a liver-protecting milk powder manufacture craft flow chart of the present invention.
A most preferred embodiment of the present invention, as figure, to make 400g milk powder is example, and Chinese medicine fruit of glossy privet 7.5g, Radix Astragali 25g, Radix Glycyrrhizae 7.5g are extracted secondary, each 2 hours with 95% alcohol reflux, then with its filtration, merge extract, filtrate is used the activated carbon decolorizing secondary, destainer is reclaimed ethanol, and to make it to become the liquid degree be 1.20, temperature is 80 ℃ a liquid extract, and the liquid extract spray-drying is just become dry powder additive; Fresh milk is checked and accepted, and weighs 2000g, purifies cooling and stores (4 ℃), with 0.28gVc, 0.008gB
1, 0.008gB
2With the 40g fruit of glossy privet, Radix Glycyrrhizae, the extract of the Radix Astragali, Rong Xie sucrose respectively, isomalto-oligosaccharide, skimmed milk power, desalted whey powder all adds the standardization of preparing burden in the fresh milk, be preheated to 50-60 ℃ then, homogeneous under the pressure of 20-25MPa, cooling is stored, sterilization, temperature 86-92 ℃, be incubated 24 seconds, concentration is 43-48%, spray-drying (wherein: 160 ℃ of air intakes after entering dense milk cold wall tank then, 80 ℃ of air drafts), the vibrated fluidized bed cooling, carry sieve powder<15 ℃, metering, vacuum nitrogen automatic gauge packing, product inspection, the certified products warehouse-in has just been finished whole technical process.
Claims (2)
1, a kind of prescription of liver-protecting milk powder is characterized in that:
Fresh milk (dry is in 11.2%) 2000 grams
Sucrose 60 grams
Isomalto-oligosaccharide 48 grams
Skimmed milk power 40 grams
Desalted whey powder 20 grams
Vitamin C 0.28 gram
Cobastab
10.008 gram
Cobastab
20.008 gram
The Radix Astragali 25 grams
Radix Glycyrrhizae 7.5 grams
The fruit of glossy privet 7.5 grams
Annotate: the Radix Astragali in the prescription, Radix Glycyrrhizae, the fruit of glossy privet are meant the raw medicinal herbs consumption, need to add in the milk powder (the extract Main Ingredients and Appearance is an oleanolic acid) after extracting.
2, a kind of production technology of liver-protecting milk powder as claimed in claim 1 is characterized in that:
Restrain milk powder in 400:
Get fresh milk (concentration is 11.2%) 2000 grams
Sucrose 60 grams
Isomalto-oligosaccharide 48 grams
Skimmed milk power 40 grams
Desalted whey powder 20 grams
Vitamin C 0.28 gram
Cobastab
10.008 gram
Cobastab
20.008 gram
The Radix Astragali 25 grams
Radix Glycyrrhizae 7.5 grams
The fruit of glossy privet 7.5 grams
Its production technology is: a, the Chinese medicine fruit of glossy privet, Radix Glycyrrhizae, the Radix Astragali are extracted secondary in 1: 1: 4 ratio with 95% alcohol reflux, each 2 hours, then with its filtration, merge extract, filtrate is used the activated carbon decolorizing secondary, destainer is reclaimed ethanol, and to make it to become concentration be 1.20, and temperature is 80 ℃ a liquid extract, and the liquid extract spray-drying is just become dry powder additive; (4 ℃) are stored in b, fresh milk examination → metering → purification → cooling, with vitamin V c, B
1, B
2(three's ratio is 35: 1: 1) all adds the standardization of preparing burden in the fresh milk with the fruit of glossy privet, the Radix Astragali, licorice in sucrose, isomalto-oligosaccharide, skimmed milk power, the desalted whey powder of 1: 13.5 ratio and dissolving respectively; C, preheating (50-60 ℃); D, homogeneous (20-25MPa); E, cooling are stored; F, sterilization, concentrated (sterilization temperature 86-92 ℃ is incubated 24 seconds, concentration 43-48%); G, enter dense milk cold wall tank; H, spray-drying, 160 ℃ of air intakes, 80 ℃ of air drafts; I, vibrated fluidized bed cooling, sieve powder (<15 ℃); Z, conveying, metering, vacuum nitrogen automatic gauge packing; Y, product inspection, the certified products warehouse-in.
Priority Applications (1)
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CN99113129A CN1102025C (en) | 1999-07-23 | 1999-07-23 | Formula of liver-protecting milk powder and its production process |
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CN99113129A CN1102025C (en) | 1999-07-23 | 1999-07-23 | Formula of liver-protecting milk powder and its production process |
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CN1253733A true CN1253733A (en) | 2000-05-24 |
CN1102025C CN1102025C (en) | 2003-02-26 |
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CN99113129A Expired - Fee Related CN1102025C (en) | 1999-07-23 | 1999-07-23 | Formula of liver-protecting milk powder and its production process |
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Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN100358428C (en) * | 2005-03-13 | 2008-01-02 | 杨军 | Dry milk piece with astragalus mongholicus for protecting stomach |
CN101264115B (en) * | 2008-05-13 | 2011-04-13 | 宋艳 | Panax ginseng total saponins and silymarin composition and preparation thereof |
CN102119731A (en) * | 2010-12-30 | 2011-07-13 | 陈慧婷 | Formulation and preparation method of milk powder capable of alleviating dysmenorrheal |
CN102934691A (en) * | 2012-11-29 | 2013-02-20 | 奉红英 | Healthcare camel milk |
CN102940040A (en) * | 2012-11-29 | 2013-02-27 | 奉红英 | Health care deer milk |
CN103262888A (en) * | 2013-04-16 | 2013-08-28 | 蚌埠市金旺食品有限公司 | Pomegranate leaf and radix astragali milk powder |
CN104082737A (en) * | 2014-06-13 | 2014-10-08 | 胡安然 | Instant food for preventing and treating hepatitis |
CN115053929A (en) * | 2022-05-23 | 2022-09-16 | 江西人之初乳品营养有限公司 | Formula milk powder suitable for people with fatty liver and preparation method thereof |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1107656A (en) * | 1994-04-05 | 1995-09-06 | 黑龙江省红光农场乳品厂 | Milk powder simulating breast milk for infants |
CN1129524A (en) * | 1994-09-09 | 1996-08-28 | 哈尔滨松花江第二乳品厂 | Milk powder for babies |
-
1999
- 1999-07-23 CN CN99113129A patent/CN1102025C/en not_active Expired - Fee Related
Cited By (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN100358428C (en) * | 2005-03-13 | 2008-01-02 | 杨军 | Dry milk piece with astragalus mongholicus for protecting stomach |
CN101264115B (en) * | 2008-05-13 | 2011-04-13 | 宋艳 | Panax ginseng total saponins and silymarin composition and preparation thereof |
CN102119731A (en) * | 2010-12-30 | 2011-07-13 | 陈慧婷 | Formulation and preparation method of milk powder capable of alleviating dysmenorrheal |
CN102119731B (en) * | 2010-12-30 | 2012-11-21 | 陈慧婷 | Formulation and preparation method of milk powder capable of alleviating dysmenorrheal |
CN102934691A (en) * | 2012-11-29 | 2013-02-20 | 奉红英 | Healthcare camel milk |
CN102940040A (en) * | 2012-11-29 | 2013-02-27 | 奉红英 | Health care deer milk |
CN103262888A (en) * | 2013-04-16 | 2013-08-28 | 蚌埠市金旺食品有限公司 | Pomegranate leaf and radix astragali milk powder |
CN104082737A (en) * | 2014-06-13 | 2014-10-08 | 胡安然 | Instant food for preventing and treating hepatitis |
CN115053929A (en) * | 2022-05-23 | 2022-09-16 | 江西人之初乳品营养有限公司 | Formula milk powder suitable for people with fatty liver and preparation method thereof |
CN115053929B (en) * | 2022-05-23 | 2024-04-23 | 江西人之初乳品营养有限公司 | Formula milk powder suitable for fatty liver people and preparation thereof |
Also Published As
Publication number | Publication date |
---|---|
CN1102025C (en) | 2003-02-26 |
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