CN1252049A - 2-取代的苯甲酰基-环烷基-1-羧酸衍生物 - Google Patents
2-取代的苯甲酰基-环烷基-1-羧酸衍生物 Download PDFInfo
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- CN1252049A CN1252049A CN98804144A CN98804144A CN1252049A CN 1252049 A CN1252049 A CN 1252049A CN 98804144 A CN98804144 A CN 98804144A CN 98804144 A CN98804144 A CN 98804144A CN 1252049 A CN1252049 A CN 1252049A
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- carboxylic acid
- cyclopropane
- hydrogen
- dichloro
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Images
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- C—CHEMISTRY; METALLURGY
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- C07C233/81—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
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- C07C62/18—Saturated compounds containing keto groups
- C07C62/20—Saturated compounds containing keto groups with a saturated six-membered ring
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/46—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C229/48—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups and carboxyl groups bound to carbon atoms of the same non-condensed ring
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- C07C233/00—Carboxylic acid amides
- C07C233/57—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C233/60—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
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- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/70—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/82—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring
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- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/24—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a ring other than a six-membered aromatic ring
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- C07C271/62—Compounds containing any of the groups, X being a hetero atom, Y being any atom, e.g. N-acylcarbamates
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- C07C311/50—Compounds containing any of the groups, X being a hetero atom, Y being any atom
- C07C311/51—Y being a hydrogen or a carbon atom
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- C07C62/30—Unsaturated compounds
- C07C62/38—Unsaturated compounds containing keto groups
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- C07—ORGANIC CHEMISTRY
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- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/74—Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring
- C07C69/757—Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/04—Systems containing only non-condensed rings with a four-membered ring
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
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- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
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- Biomedical Technology (AREA)
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- Psychiatry (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
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- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
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GB9705031.4 | 1997-03-11 | ||
GBGB9705031.4A GB9705031D0 (en) | 1997-03-11 | 1997-03-11 | 2-substituted benzoyl-cycloalkyl-1-carboxylic acid derivatives |
Publications (1)
Publication Number | Publication Date |
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CN1252049A true CN1252049A (zh) | 2000-05-03 |
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ID=10809053
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CN98804144A Pending CN1252049A (zh) | 1997-03-11 | 1998-02-16 | 2-取代的苯甲酰基-环烷基-1-羧酸衍生物 |
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EP (1) | EP0973720A1 (xx) |
JP (1) | JP2001514634A (xx) |
KR (1) | KR20000076096A (xx) |
CN (1) | CN1252049A (xx) |
AU (1) | AU6497998A (xx) |
CA (1) | CA2283184A1 (xx) |
EA (1) | EA199900809A1 (xx) |
GB (1) | GB9705031D0 (xx) |
HU (1) | HUP0001023A3 (xx) |
IL (1) | IL131676A0 (xx) |
NO (1) | NO994386L (xx) |
PL (1) | PL335601A1 (xx) |
TW (1) | TW407146B (xx) |
WO (1) | WO1998040344A1 (xx) |
ZA (1) | ZA981972B (xx) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103373911A (zh) * | 2012-04-27 | 2013-10-30 | 中国科学院上海有机化学研究所 | 单氟代环丙烷类化合物及其制备方法和应用 |
CN104119246A (zh) * | 2013-04-26 | 2014-10-29 | 中国科学院上海有机化学研究所 | 环丙烷衍生物及其制备方法和应用 |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1424333A1 (en) * | 2002-11-28 | 2004-06-02 | Newron Pharmaceuticals S.p.A. | Halothenoyl-cyclopropane-1-carboxylic acid derivatives |
EP1475088A1 (en) * | 2003-05-05 | 2004-11-10 | Newron Pharmaceuticals S.p.A. | Use of kynurenine-3-hydroxylase inhibitors for the preparation of medicaments for the treatment of l-dopa induced movement disorders, dyskinesias, drug addiction, pain and cataract |
EP1475385A1 (en) * | 2003-05-05 | 2004-11-10 | Newron Pharmaceuticals S.p.A. | Glycoside derivatives of 2-(3,4-dichlorobenzoyl)-cycopropane-1-carboxylic acid |
WO2013151707A1 (en) * | 2012-04-05 | 2013-10-10 | Chdi Foundation, Inc. | Kynurenine-3-monooxygenase inhibitors, pharmaceutical compositions, and methods of use thereof |
WO2015047982A2 (en) | 2013-09-26 | 2015-04-02 | Chdi Foundation, Inc. | Kynurenine-3-monooxygenase inhibitors, pharmaceutical compositions, and methods of use thereof |
JP6449893B2 (ja) * | 2013-09-26 | 2019-01-09 | シーエイチディーアイ ファウンデーション,インコーポレーテッド | キヌレニン−3−モノオキシゲナーゼ阻害薬、医薬組成物、及びこれらの使用方法 |
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US3655667A (en) * | 1968-04-04 | 1972-04-11 | Smith Kline French Lab | 1-(2-benzoylcyclopropylmethyl)-4-phenylpiperazines |
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1997
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1998
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1999
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Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103373911A (zh) * | 2012-04-27 | 2013-10-30 | 中国科学院上海有机化学研究所 | 单氟代环丙烷类化合物及其制备方法和应用 |
CN103373911B (zh) * | 2012-04-27 | 2016-12-14 | 中国科学院上海有机化学研究所 | 单氟代环丙烷类化合物及其制备方法和应用 |
CN104119246A (zh) * | 2013-04-26 | 2014-10-29 | 中国科学院上海有机化学研究所 | 环丙烷衍生物及其制备方法和应用 |
Also Published As
Publication number | Publication date |
---|---|
KR20000076096A (ko) | 2000-12-26 |
AU6497998A (en) | 1998-09-29 |
EA199900809A1 (ru) | 2000-08-28 |
WO1998040344A1 (en) | 1998-09-17 |
JP2001514634A (ja) | 2001-09-11 |
IL131676A0 (en) | 2001-03-19 |
NO994386L (no) | 1999-11-02 |
HUP0001023A3 (en) | 2001-03-28 |
CA2283184A1 (en) | 1998-09-17 |
PL335601A1 (en) | 2000-05-08 |
TW407146B (en) | 2000-10-01 |
GB9705031D0 (en) | 1997-04-30 |
ZA981972B (en) | 1998-09-09 |
EP0973720A1 (en) | 2000-01-26 |
HUP0001023A2 (hu) | 2000-09-28 |
NO994386D0 (no) | 1999-09-10 |
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